Lee Ratner - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Microbiology Biology

274 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Poondru S, Joseph A, Harding JC, Sundaramoorthi H, Mehta-Shah N, Green P, Hassan A, Rauch DA, Ratner L. Adult T-Cell Leukemia-Lymphoma Presenting Concurrently with Myelopathy. Case Reports in Oncology. 15: 918-926. PMID 36636671 DOI: 10.1159/000525174  0.337
2021 Ratner L. Epigenetic Regulation of Human T-Cell Leukemia Virus Gene Expression. Microorganisms. 10. PMID 35056532 DOI: 10.3390/microorganisms10010084  0.302
2021 Cheng X, Joseph A, Castro V, Chen-Liaw A, Skidmore Z, Payton JE, Ratner L, Edwards JR, Ueno T, Fujisawa JI, Rauch DA, Challen GA, Martinez MP, Green P, Griffith M. Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF. Plos Pathogens. 17: e1009577. PMID 34019588 DOI: 10.1371/journal.ppat.1009577  0.316
2020 Rauch DA, Olson SL, Harding JC, Sundaramoorthi H, Kim Y, Zhou T, MacLeod AR, Challen G, Ratner L. Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma. Retrovirology. 17: 27. PMID 32859220 DOI: 10.1186/S12977-020-00535-Z  0.441
2020 Ratner L. Predicting the future: adult T-cell leukemia. Blood. 135: 2013-2014. PMID 32497221 DOI: 10.1182/Blood.2020005552  0.404
2020 Ramos JC, Sparano JA, Chadburn A, Reid EG, Ambinder RF, Siegel ER, Moore PC, Rubinstein PG, Durand C, Cesarman E, Aboulafia DM, Baiocchi RA, Ratner L, Kaplan LD, Capoferri AA, et al. Impact of Myc in HIV-associated Non-Hodgkin Lymphomas Treated with EPOCH, and Outcomes with Vorinostat (AMC075 Trial). Blood. PMID 32430507 DOI: 10.1182/Blood.2019003959  0.383
2020 Sparano JA, Lee JY, Kaplan LD, Ramos JC, Ambinder RF, Wachsman W, Aboulafia D, Noy A, Henry DH, Ratner L, Cesarman E, Chadburn A, Mitsuyasu R. Response-adapted therapy with infusional EPOCH chemotherapy plus rituximab in HIV- associated, B-cell non-Hodgkin's lymphoma. Haematologica. PMID 32107337 DOI: 10.3324/Haematol.2019.243386  0.331
2019 Martinez MP, Cheng X, Joseph A, Al-Saleem J, Panfil AR, Palettas M, Dirksen WP, Ratner L, Green PL. HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo. Retrovirology. 16: 44. PMID 31864373 DOI: 10.1186/S12977-019-0507-9  0.418
2019 Kisaka JK, Ratner L, Kyei GB. The dual specificity kinase DYRK1A modulates the levels of cyclin L2 to control HIV replication in macrophages. Journal of Virology. PMID 31852782 DOI: 10.1128/Jvi.01583-19  0.399
2019 Ratner L. Biomarkers and Preclinical Models for Adult T-Cell Leukemia-Lymphoma Treatment. Frontiers in Microbiology. 10: 2109. PMID 31620102 DOI: 10.3389/Fmicb.2019.02109  0.34
2019 Xiang J, Rauch DA, Huey DD, Panfil AR, Cheng X, Esser AK, Su X, Harding JC, Xu Y, Fox GC, Fontana F, Kobayashi T, Su J, Sundaramoorthi H, Wong WH, ... ... Ratner L, et al. HTLV-1 viral oncogene HBZ drives bone destruction in adult T cell leukemia. Jci Insight. 4. PMID 31578308 DOI: 10.1172/Jci.Insight.128713  0.371
2019 Rauch DA, Conlon KC, Janakiram M, Brammer JE, Harding JC, Ye BH, Zang X, Ren X, Olson S, Cheng X, Miljkovic MD, Sundaramoorthi H, Joseph A, Skidmore ZL, Griffith O, ... ... Ratner L, et al. . Blood. PMID 31467059 DOI: 10.1182/Blood.2019002038  0.327
2019 Malu A, Hutchison T, Yapindi L, Smith K, Nelson K, Bergeson R, Pope J, Romeo M, Harrod C, Ratner L, Van Lint C, Harrod R. The human T-cell leukemia virus type-1 tax oncoprotein dissociates NF-κB p65-Stathmin complexes and causes catastrophic mitotic spindle damage and genomic instability. Virology. 535: 83-101. PMID 31299491 DOI: 10.1016/J.Virol.2019.07.003  0.384
2019 Ratner L. Molecular biology of human T cell leukemia virus. Seminars in Diagnostic Pathology. PMID 31103249 DOI: 10.1053/J.Semdp.2019.04.003  0.505
2019 Al-Saleem J, Dirksen WP, Martinez MP, Shkriabai N, Kvaratskhelia M, Ratner L, Green PL. HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1. Plos One. 14: e0214059. PMID 30897179 DOI: 10.1371/Journal.Pone.0214059  0.452
2019 Reid E, Suneja G, Ambinder RF, Ard K, Baiocchi R, Barta SK, Carchman E, Cohen A, Crysler OV, Gupta N, Gustafson C, Hall A, Johung KL, Klopp A, LaCasce AS, ... ... Ratner L, et al. AIDS-Related Kaposi Sarcoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : Jnccn. 17: 171-189. PMID 30787130 DOI: 10.6004/Jnccn.2019.0008  0.315
2019 Cook LB, Fuji S, Hermine O, Bazarbachi A, Ramos JC, Ratner L, Horwitz S, Fields P, Tanase A, Bumbea H, Cwynarski K, Taylor G, Waldmann TA, Bittencourt A, Marcais A, et al. Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1800501. PMID 30657736 DOI: 10.1200/Jco.18.00501  0.399
2019 Ramos JC, Sparano J, Moore PC, Siegel E, Lee JY, Reid EG, Ambinder RF, Chadburn A, Rubinstein PG, Durand C, Cesarman E, Ratner L, Baiocchi RA, Aboulafia DM, Kaplan LD, et al. A Randomized Trial of EPOCH-Based Chemotherapy with Vorinostat for Highly Aggressive HIV-Associated Lymphomas: Updated Results Evaluating Impact of Diagnosis-to-Treatment Interval (DTI) and Pre-Protocol Systemic Therapy on Outcomes Blood. 134: 1588-1588. DOI: 10.1182/Blood-2019-129687  0.381
2019 Rubinstein PG, Moore PC, Bimali M, Chadburn A, Cesarman E, Rudek M, Ratner L, Ambinder RF, Henry DH, Barta SK, Ghesquieres H, Coppo P, Delobel P, Boue F, Galicier L, et al. Safety and Efficacy of Brentuximab Vedotin in Combination with AVD in Stage II-IV HIV-Associated Classical Hodgkin Lymphoma: Results of the Phase 2 Study, AMC 085 Blood. 134: 130-130. DOI: 10.1182/Blood-2019-126787  0.38
2018 Kyei GB, Meng S, Ramani R, Niu A, Lagisetti C, Webb TR, Ratner L. Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency. Mbio. 9. PMID 30401776 DOI: 10.1128/Mbio.01423-18  0.465
2018 Shah UA, Chung EY, Giricz O, Pradhan K, Kataoka K, Gordon-Mitchell S, Bhagat TD, Mai Y, Wei Y, Ishida E, Choudhary GS, Joseph A, Rice R, Gitego N, Parrish C, ... ... Ratner L, et al. North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies. Blood. PMID 30104217 DOI: 10.1182/Blood-2018-01-824607  0.314
2018 Hutchison T, Malu A, Yapindi L, Bergeson R, Peck K, Romeo M, Harrod C, Pope J, Smitherman L, Gwinn W, Ratner L, Yates C, Harrod R. The TP53-Induced Glycolysis and Apoptosis Regulator mediates cooperation between HTLV-1 p30 and the retroviral oncoproteins Tax and HBZ and is highly expressed in an in vivo xenograft model of HTLV-1-induced lymphoma. Virology. 520: 39-58. PMID 29777913 DOI: 10.1016/J.Virol.2018.05.007  0.483
2018 Ratner L, Waldmann TA, Janakiram M, Brammer JE. Rapid Progression of Adult T-Cell Leukemia-Lymphoma after PD-1 Inhibitor Therapy. The New England Journal of Medicine. 378: 1947-1948. PMID 29768155 DOI: 10.1056/Nejmc1803181  0.384
2018 Pérès E, Blin J, Ricci EP, Artesi M, Hahaut V, Van den Broeke A, Corbin A, Gazzolo L, Ratner L, Jalinot P, Duc Dodon M. PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice. Plos Pathogens. 14: e1006933. PMID 29566098 DOI: 10.1371/Journal.Ppat.1006933  0.458
2018 Cherian MA, Olson S, Sundaramoorthi H, Cates K, Cheng X, Harding J, Martens A, Challen GA, Tyagi M, Ratner L, Rauch D. An activating mutation of interferon regulatory factor 4 (IRF4) in adult T cell leukemia. The Journal of Biological Chemistry. PMID 29540473 DOI: 10.1074/Jbc.Ra117.000164  0.461
2018 Romeo M, Hutchison T, Malu A, White A, Kim J, Gardner R, Smith K, Nelson K, Bergeson R, McKee R, Harrod C, Ratner L, Lüscher B, Martinez E, Harrod R. The human T-cell leukemia virus type-1 p30protein activates p53 and induces the TIGAR and suppresses oncogene-induced oxidative stress during viral carcinogenesis. Virology. 518: 103-115. PMID 29462755 DOI: 10.1016/J.Virol.2018.02.010  0.413
2018 Huey DD, Bolon B, La Perle KMD, Kannian P, Jacobson S, Ratner L, Green PL, Niewiesk S. Role of Wild-type and Recombinant Human T-cell Leukemia Viruses in Lymphoproliferative Disease in Humanized NSG Mice. Comparative Medicine. 68: 4-14. PMID 29460716  0.387
2018 Ramos JC, Sparano JA, Rudek MA, Moore PC, Cesarman E, Reid EG, Henry D, Ratner L, Aboulafia D, Lee JY, Ambinder RF, Mitsuyasu R, Noy A. Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin's Lymphoma (AMC-075). Clinical Lymphoma, Myeloma & Leukemia. PMID 29426719 DOI: 10.1016/J.Clml.2018.01.004  0.439
2018 Ramos JC, Sparano JA, Moore PC, Cesarman E, Reid EG, Rubinstein PG, Harrington RD, Baiocchi RA, Aboulafia DM, Ratner L, Lawrence K, Durand C, Ambinder R, Lee JY, Mitsuyasu RT, et al. AMC075: A randomized phase II trial of vorinostat with R-EPOCH in aggressive HIV-related NHL. Journal of Clinical Oncology. 36: 7573-7573. DOI: 10.1200/Jco.2018.36.15_Suppl.7573  0.332
2018 Gru A, Barrionuevo C, Pulitzer M, Sanches JA, Miyashiro D, Duenas D, Servitje O, Esteller FC, Ratner L, Zambrano SC, Williams E, Davick J. Clinicopathologic characteristics, prognostic and predictive biomarkers in adult T-cell leukemia/lymphoma (ATLL): A characterization of 79 cases from the Western Hemisphere European Journal of Cancer. 101. DOI: 10.1016/J.Ejca.2018.07.184  0.315
2018 Davick J, Williams E, Barrionuevo C, Pulitzer M, Sanchez JA, Miyashiro D, Casavilca S, Duenas D, Ratner L, Ramos JC, Servitje O, Esteller FC, Gru A. Genomic alterations using OncoScan in adult T-cell leukemia/lymphoma: A characterization of 69 cases from Peru, the United States, Brazil, and Spain European Journal of Cancer. 101. DOI: 10.1016/J.Ejca.2018.07.182  0.318
2017 Rubinstein PG, Moore PC, Rudek MA, Henry DH, Ramos JC, Ratner L, Reid E, Sharon E, Noy A. Brentuximab vedotin with AVD shows safety, in the absence of strong CYP3A4 inhibitors, in newly diagnosed HIV-associated Hodgkin lymphoma. Aids (London, England). PMID 29280762 DOI: 10.1097/Qad.0000000000001729  0.366
2017 Esser AK, Rauch DA, Xiang J, Harding JC, Kohart NA, Ross MH, Su X, Wu K, Huey D, Xu Y, Vij K, Green PL, Rosol TJ, Niewiesk S, Ratner L, et al. HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice. Oncotarget. 8: 69250-69263. PMID 29050201 DOI: 10.18632/Oncotarget.20565  0.345
2017 Mehta-Shah N, Ratner L, Horwitz SM. Adult T-Cell Leukemia/Lymphoma. Journal of Oncology Practice. 13: 487-492. PMID 28796966 DOI: 10.1200/Jop.2017.021907  0.377
2017 Albert BJ, Niu A, Ramani R, Marshall GR, Wender PA, Williams RM, Ratner L, Barnes AB, Kyei GB. Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation. Scientific Reports. 7: 7456. PMID 28785069 DOI: 10.1038/S41598-017-07814-4  0.445
2017 Wagner-Johnston ND, Lensing S, Noy A, Ratner L, Henry D, Lee JY, Silver S, Faham M, Ambinder RF. High frequency of identical clonal immunoglobulin DNA in pre-treatment tumor and plasma from untreated patients with HIV-associated lymphoma: prospective multicenter trial of the AIDS malignancies consortium (AMC 064). Leukemia & Lymphoma. 1-4. PMID 28508728 DOI: 10.1080/10428194.2017.1317095  0.361
2017 Haigentz M, Moore PC, Ratner L, Henry DH, Rubinstein PG, Ramos JC, Rudek MA, Eng Y, Cooley TP, Deeken JF, Little RF, Mitsuyasu RT. Tolerability of paclitaxel/carboplatin (PCb) in solid tumor patients (pts) infected with HIV. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.E14077  0.353
2016 Sparano JA, Lee JY, Palefsky J, Henry DH, Wachsman W, Rajdev L, Aboulafia D, Ratner L, Fitzgerald TJ, Kachnic L, Mitsuyasu R. Cetuximab Plus Chemoradiotherapy for HIV-Associated Anal Carcinoma: A Phase II AIDS Malignancy Consortium Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016691642. PMID 27937092 DOI: 10.1200/Jco.2016.69.1642  0.372
2016 Panfil AR, Martinez MP, Ratner L, Green PL. Human T-cell leukemia virus-associated malignancy. Current Opinion in Virology. 20: 40-46. PMID 27591679 DOI: 10.1016/J.Coviro.2016.08.009  0.444
2016 Zhang J, Gao X, Martin J, Rosa B, Chen Z, Mitreva M, Henrich T, Kuritzkes D, Ratner L. Evolution of coreceptor utilization to escape CCR5 antagonist therapy. Virology. 494: 198-214. PMID 27128349 DOI: 10.1016/J.Virol.2016.04.010  0.367
2016 Murphy J, Hall WW, Ratner L, Sheehy N. Novel interactions between the HTLV antisense proteins HBZ and APH-2 and the NFAR protein family: Implications for the HTLV lifecycles. Virology. 494: 129-142. PMID 27110706 DOI: 10.1016/J.Virol.2016.04.012  0.414
2016 Ratner L, Rauch D, Abel H, Caruso B, Noy A, Barta SK, Parekh S, Ramos JC, Ambinder R, Phillips A, Harding J, Baydoun HH, Cheng X, Jacobson S. Dose-adjusted EPOCH chemotherapy with bortezomib and raltegravir for human T-cell leukemia virus-associated adult T-cell leukemia lymphoma. Blood Cancer Journal. 6: e408. PMID 27015285 DOI: 10.1038/Bcj.2016.21  0.43
2016 Yeh CH, Bai XT, Moles R, Ratner L, Waldmann TA, Watanabe T, Nicot C. Erratum to: 'Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia'. Molecular Cancer. 15: 20. PMID 26936184 DOI: 10.1186/S12943-016-0504-8  0.348
2016 Yeh CH, Bai XT, Moles R, Ratner L, Waldmann TA, Toshiki W, Nicot C. Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia. Molecular Cancer. 15: 15. PMID 26880370 DOI: 10.1186/S12943-016-0500-Z  0.345
2016 Garg M, Zhao F, Lee JY, Sparano JA, Palefsky J, Henry DH, Wachsman W, Rajdev L, Aboulafia DM, Ratner L, Kachnic LA, Mitchell EP, Onitilo AA, Mitsuyasu RT, Benson AB. Phase II trials of cetuximab plus combined modality therapy (CMT) in squamous cell carcinoma of the anal canal (SCCAC) with and without human immunodeficiency virus (HIV) infection. Journal of Clinical Oncology. 34: 3522-3522. DOI: 10.1200/Jco.2016.34.15_Suppl.3522  0.439
2016 Esser A, Rauch D, Xiang J, Harding J, Kohart N, Green P, Niewiesk S, Rosol T, Ratner L, Weilbaecher K. Abstract 3285: HTLV-1 viral oncogene Hbz induces leukemia with osteolytic bone involvement in mice Cancer Research. 76: 3285-3285. DOI: 10.1158/1538-7445.Am2016-3285  0.322
2015 Noy A, Lensing SY, Moore PC, Gupta N, Aboulafia D, Ambinder R, Baiocchi R, Dezube BJ, Henry D, Kaplan L, Levine AM, Mitsuyasu R, Ratner L, Reid E, Remick S, et al. Plasmablastic lymphoma is treatable in the HAART era. A 10 year retrospective by the AIDS Malignancy Consortium. Leukemia & Lymphoma. 1-4. PMID 26674561 DOI: 10.3109/10428194.2015.1113281  0.359
2015 Bangham CR, Ratner L. How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)? Current Opinion in Virology. 14: 93-100. PMID 26414684 DOI: 10.1016/J.Coviro.2015.09.004  0.432
2015 Cherian MA, Baydoun HH, Al-Saleem J, Shkriabai N, Kvaratskhelia M, Green P, Ratner L. Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein. The Journal of Biological Chemistry. 290: 26270-81. PMID 26324707 DOI: 10.1074/Jbc.M115.684746  0.456
2015 Baydoun HH, Cherian MA, Green P, Ratner L. Inducible nitric oxide synthase mediates DNA double strand breaks in Human T-Cell Leukemia Virus Type 1-induced leukemia/lymphoma. Retrovirology. 12: 71. PMID 26265053 DOI: 10.1186/S12977-015-0196-Y  0.425
2015 Noy A, Lee JY, Cesarman E, Ambinder R, Baiocchi R, Reid E, Ratner L, Wagner-Johnston N, Kaplan L. AMC 048: modified CODOX-M/IVAC-rituximab is safe and effective for HIV-associated Burkitt lymphoma. Blood. 126: 160-6. PMID 25957391 DOI: 10.1182/Blood-2015-01-623900  0.338
2015 Pujari R, Hunte R, Thomas R, van der Weyden L, Rauch D, Ratner L, Nyborg JK, Ramos JC, Takai Y, Shembade N. Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling. Plos Pathogens. 11: e1004721. PMID 25774694 DOI: 10.1371/Journal.Ppat.1004721  0.366
2015 Barta SK, Samuel MS, Xue X, Wang D, Lee JY, Mounier N, Ribera JM, Spina M, Tirelli U, Weiss R, Galicier L, Boue F, Little RF, Dunleavy K, Wilson WH, ... ... Ratner L, et al. Changes in the influence of lymphoma- and HIV-specific factors on outcomes in AIDS-related non-Hodgkin lymphoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 958-66. PMID 25632071 DOI: 10.1093/Annonc/Mdv036  0.341
2015 Romeo MM, Ko B, Kim J, Brady R, Heatley HC, He J, Harrod CK, Barnett B, Ratner L, Lairmore MD, Martinez E, Lüscher B, Robson CN, Henriksson M, Harrod R. Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC. Virology. 476: 271-88. PMID 25569455 DOI: 10.1016/J.Virol.2014.12.008  0.34
2015 Kyei GB, Cheng X, Ramani R, Ratner L. Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance. Cell Host & Microbe. 17: 98-106. PMID 25532805 DOI: 10.1016/J.Chom.2014.11.009  0.386
2015 H. Baydoun H, Ratner L. Contribution of Inducible Nitric Oxide Synthase to the Transformation of HTLV-1 Infected CD4+ T-Cells Journal of Leukemia. 3. DOI: 10.4172/2329-6917.1000199  0.412
2015 Cherian M, Baydoun H, Al-Saleem J, Kvaratskhelia M, Green P, Ratner L. Akt activation by human T-cell leukemia virus tax oncoprotein Retrovirology. 12: 54. DOI: 10.1186/1742-4690-12-S1-P54  0.444
2015 Ratner L, Ramos J, Noy A, Barta S, Parikh S, Phillips A, Ambinder R, Rauch D, Harding J, Baydoun H, Cheng X, Caruso B, Jacobson S. Phase I / II trial of dose adjusted EPOCH chemotherapy with bortezomib combined with integrase inhibitor therapy for HTLV-1 associated T-cell leukemia lymphoma Retrovirology. 12. DOI: 10.1186/1742-4690-12-S1-P21  0.336
2015 Rubinstein PG, Moore P, Henry DH, Ratner L, Sharon E, Noy A. AMC-085: A Pilot Trial of AVD and Brentuximab Vedotin in the Upfront Treatment of Stage II-IV HIV-Associated Hodgkin Lymphoma. A Trial of the AIDS Malignancy Consortium Blood. 126: 1526-1526. DOI: 10.1182/Blood.V126.23.1526.1526  0.356
2014 Barbeau B, Hiscott J, Bazarbachi A, Carvalho E, Jones K, Martin F, Matsuoka M, Murphy EL, Ratner L, Switzer WM, Watanabe T. Conference highlights of the 16th International Conference on Human Retrovirology: HTLV and related retroviruses, 26-30 June 2013, Montreal, Canada. Retrovirology. 11: 19. PMID 24558960 DOI: 10.1186/1742-4690-11-19  0.305
2014 Cheng X, Ratner L. HIV-2 Vpx protein interacts with interferon regulatory factor 5 (IRF5) and inhibits its function. The Journal of Biological Chemistry. 289: 9146-57. PMID 24532789 DOI: 10.1074/Jbc.M113.534321  0.398
2014 Rudek MA, Moore PC, Mitsuyasu RT, Dezube BJ, Aboulafia D, Gerecitano J, Sullivan R, Cianfrocca ME, Henry DH, Ratner L, Haigentz M, Dowlati A, Little RF, Ivy SP, Deeken JF. A phase 1/pharmacokinetic study of sunitinib in combination with highly active antiretroviral therapy in human immunodeficiency virus-positive patients with cancer: AIDS Malignancy Consortium trial AMC 061. Cancer. 120: 1194-202. PMID 24474568 DOI: 10.1002/Cncr.28554  0.351
2014 Baydoun HH, Ratner L. Tax inflicts DNA damage through activation of Nitric Oxide production Retrovirology. 11: 107. DOI: 10.1186/1742-4690-11-S1-P107  0.41
2013 Cachat A, Chevalier SA, Alais S, Ko NL, Ratner L, Journo C, Dutartre H, Mahieux R. Alpha interferon restricts human T-lymphotropic virus type 1 and 2 de novo infection through PKR activation. Journal of Virology. 87: 13386-96. PMID 24089560 DOI: 10.1128/Jvi.02758-13  0.432
2013 Barta SK, Xue X, Wang D, Tamari R, Lee JY, Mounier N, Kaplan LD, Ribera JM, Spina M, Tirelli U, Weiss R, Galicier L, Boue F, Wilson WH, Wyen C, ... ... Ratner L, et al. Treatment factors affecting outcomes in HIV-associated non-Hodgkin lymphomas: a pooled analysis of 1546 patients. Blood. 122: 3251-62. PMID 24014242 DOI: 10.1182/Blood-2013-04-498964  0.312
2013 Hood JL, Jallouk AP, Campbell N, Ratner L, Wickline SA. Cytolytic nanoparticles attenuate HIV-1 infectivity. Antiviral Therapy. 18: 95-103. PMID 22954649 DOI: 10.3851/Imp2346  0.369
2013 Baydoun H, Ratner L. Abstract LB-127: HTLV-1 Tax inflicts severe DNA damage through the activation of nitric oxide production: A credible pathway for transformation of HTLV-1 infected cells. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-127  0.389
2012 Zane L, Yasunaga J, Mitagami Y, Yedavalli V, Tang SW, Chen CY, Ratner L, Lu X, Jeang KT. Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis. Retrovirology. 9: 114. PMID 23256545 DOI: 10.1186/1742-4690-9-114  0.487
2012 Belshan M, Kimata JT, Brown C, Cheng X, McCulley A, Larsen A, Thippeshappa R, Hodara V, Giavedoni L, Hirsch V, Ratner L. Vpx is critical for SIVmne infection of pigtail macaques. Retrovirology. 9: 32. PMID 22531456 DOI: 10.1186/1742-4690-9-32  0.362
2012 McCulley A, Ratner L. HIV-2 viral protein X (Vpx) ubiquitination is dispensable for ubiquitin ligase interaction and effects on macrophage infection. Virology. 427: 67-75. PMID 22386056 DOI: 10.1016/J.Virol.2012.02.002  0.434
2012 Barta SK, Xue X, Tamari R, Lee JY, Mounier N, Kaplan LD, Ribera J, Spina M, Weiss R, Galicier L, Boue F, Wilson WH, Wyen C, Navarro J, Dunleavy K, ... ... Ratner L, et al. A pooled analysis of 1,144 patients with HIV-associated lymphoma: Assessment of lymphoma-, HIV-, and treatment-specific factors on clinical outcomes. Journal of Clinical Oncology. 30: 8005-8005. DOI: 10.1200/Jco.2012.30.15_Suppl.8005  0.332
2012 Garg M, Lee JY, Kachnic LA, Catalano PJ, Henry DH, Cooley TP, Ratner L, Wachsman W, Aboulafia DM, Benson AB, Palefsky J, Whittington R, Mitsuyasu RT, Sparano JA. Phase II trials of cetuximab (CX) plus cisplatin (CDDP), 5-fluorouracil (5-FU) and radiation (RT) in immunocompetent (ECOG 3205) and HIV-positive (AMC045) patients with squamous cell carcinoma of the anal canal (SCAC): Safety and preliminary efficacy results. Journal of Clinical Oncology. 30: 4030-4030. DOI: 10.1200/Jco.2012.30.15_Suppl.4030  0.3
2012 Deeken JF, Rudek MA, Moore PC, Aboulafia D, Sullivan R, Gerecitano J, Cianfrocca M, Henry D, Ratner L, Dezube B, Mosby K, Tibbals M, Little RF, Ivy SP, Mitsuyasu RT. A phase 1/PK study of Sunitinib with highly active antiretroviral therapy (HAART) in HIV+ patients with solid tumors: AIDS malignancy consortium study 061 Infectious Agents and Cancer. 7: 1-2. DOI: 10.1186/1750-9378-7-S1-O15  0.344
2012 Barta SK, Xue X, Wang D, Tamari R, Lee JY, Mounier N, Kaplan LD, Ribera J, Spina M, Tirelli U, Weiss R, Galicier L, Boue F, Wilson WH, Wyen C, ... ... Ratner L, et al. A Pooled Analysis of 1,546 Patients with HIV-Associated Lymphoma: Assessment of Lymphoma-, HIV-, and Treatment-Specific Factors On Clinical Outcomes Blood. 120: 3682-3682. DOI: 10.1182/Blood.V120.21.3682.3682  0.353
2011 Deeken JF, Rudek MA, Aboulafia DM, Sullivan RJ, Gerecitano JF, Cianfrocca ME, Henry DH, Ratner L, Dezube BJ, Mosby K, Tibbals M, Little RF, Ivy SP, Moore PC, Mitsuyasu RT. AIDS malignancy consortium (AMC) study 061: A phase I/PK study of sunitinib (S) with highly active antiretroviral therapy (HAART) in HIV+ patients with solid tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2591. PMID 28022235 DOI: 10.1200/Jco.2011.29.15_Suppl.2591  0.351
2011 Lairmore MD, Anupam R, Bowden N, Haines R, Haynes RA, Ratner L, Green PL. Molecular determinants of human T-lymphotropic virus type 1 transmission and spread. Viruses. 3: 1131-65. PMID 21994774 DOI: 10.3390/V3071131  0.487
2011 Rauch DA, Ratner L. Targeting HTLV-1 activation of NFκB in mouse models and ATLL patients. Viruses. 3: 886-900. PMID 21994759 DOI: 10.3390/V3060886  0.434
2011 Seegulam ME, Ratner L. Integrase inhibitors effective against human T-cell leukemia virus type 1. Antimicrobial Agents and Chemotherapy. 55: 2011-7. PMID 21343468 DOI: 10.1128/Aac.01413-10  0.794
2011 Ratner L. JAK blockade and HTLV. Blood. 117: 1771-2. PMID 21310928 DOI: 10.1182/Blood-2010-12-322008  0.325
2011 Choudhary G, Ratner L. The HTLV-1 hbz antisense gene indirectly promotes tax expression via down-regulation of p30(II) mRNA. Virology. 410: 307-15. PMID 21176937 DOI: 10.1016/J.Virol.2010.11.019  0.603
2011 Rauch D, Bokhari S, Harding J, Ratner L. Tet-inducible lymphoma in a new Tax transgenic mouse model Retrovirology. 8: A4. DOI: 10.1186/1742-4690-8-S1-A4  0.326
2011 Choudhary G, Rauch D, Ratner L. The HTLV-1 hbz antisense gene indirectly promotes tax expression via down-regulation of p30-II mRNA Retrovirology. 8: A136. DOI: 10.1186/1742-4690-8-S1-A136  0.604
2010 Harmon B, Campbell N, Ratner L. Role of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion step. Plos Pathogens. 6: e1000956. PMID 20585556 DOI: 10.1371/Journal.Ppat.1000956  0.646
2010 Zhang M, Evans S, Yuan J, Ratner L, Koka PS. HIV-1 determinants of thrombocytopenia at the stage of CD34+ progenitor cell differentiation in vivo lie in the viral envelope gp120 V3 loop region. Virology. 401: 131-6. PMID 20338611 DOI: 10.1016/J.Virol.2010.03.005  0.441
2010 Sparano JA, Lee JY, Kaplan LD, Levine AM, Ramos JC, Ambinder RF, Wachsman W, Aboulafia D, Noy A, Henry DH, Von Roenn J, Dezube BJ, Remick SC, Shah MH, Leichman L, ... Ratner L, et al. Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma. Blood. 115: 3008-16. PMID 20023215 DOI: 10.1182/Blood-2009-08-231613  0.355
2009 Rauch D, Gross S, Harding J, Bokhari S, Niewiesk S, Lairmore M, Piwnica-Worms D, Ratner L. T-cell activation promotes tumorigenesis in inflammation-associated cancer. Retrovirology. 6: 116. PMID 20017942 DOI: 10.1186/1742-4690-6-116  0.379
2009 Mansouri S, Choudhary G, Sarzala PM, Ratner L, Hudak KA. Suppression of human T-cell leukemia virus I gene expression by pokeweed antiviral protein. The Journal of Biological Chemistry. 284: 31453-62. PMID 19748897 DOI: 10.1074/Jbc.M109.046235  0.685
2009 Taylor JM, Brown M, Nejmeddine M, Kim KJ, Ratner L, Lairmore M, Nicot C. Novel role for interleukin-2 receptor-jak signaling in retrovirus transmission Journal of Virology. 83: 11467-11476. PMID 19726513 DOI: 10.1128/Jvi.00952-09  0.458
2009 Ratner L, Harrington W, Feng X, Grant C, Jacobson S, Noy A, Sparano J, Lee J, Ambinder R, Campbell N, Lairmore M. Human T cell leukemia virus reactivation with progression of adult T-cell leukemia-lymphoma. Plos One. 4: e4420. PMID 19204798 DOI: 10.1371/Journal.Pone.0004420  0.447
2009 Lodewick J, Lamsoul I, Polania A, Lebrun S, Burny A, Ratner L, Bex F. Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway. Virology. 386: 68-78. PMID 19200568 DOI: 10.1016/J.Virol.2008.12.043  0.406
2009 Tsukasaki K, Hermine O, Bazarbachi A, Ratner L, Ramos JC, Harrington W, O'Mahony D, Janik JE, Bittencourt AL, Taylor GP, Yamaguchi K, Utsunomiya A, Tobinai K, Watanabe T. Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia-lymphoma: a proposal from an international consensus meeting. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 453-9. PMID 19064971 DOI: 10.1200/Jco.2008.18.2428  0.409
2009 Bhatia AK, Kaushik R, Campbell NA, Pontow SE, Ratner L. Mutation of critical serine residues in HIV-1 matrix result in an envelope incorporation defect which can be rescued by truncation of the gp41 cytoplasmic tail. Virology. 384: 233-41. PMID 19059618 DOI: 10.1016/J.Virol.2008.10.047  0.642
2009 Rauch D, Gross S, Harding J, Niewiesk S, Lairmore M, Piwnica-Worms D, Ratner L. Imaging spontaneous tumorigenesis: inflammation precedes development of peripheral NK tumors. Blood. 113: 1493-500. PMID 18971418 DOI: 10.1182/Blood-2008-07-166462  0.392
2009 Ramachandiran S, Adone A, Guo X, Liao A, Sunay UR, Ratner L, Fu H, Lossos IS, Saavedra H, Bernal-Mizrachi L. Genomic Stability: A Novel Function of NF-Kb in Lymphomas. Blood. 114: 3240-3240. DOI: 10.1182/Blood.V114.22.3240.3240  0.358
2009 Ratner L. Book Review Human Cancer Viruses: Principles of Transformation and Pathogenesis (Translational Research in Biomedicine. Vol. 1.) Edited by John Nicholas, Kuan-Teh Jeang, and T.-C. Wu. 244 pp., illustrated. Basel, Switzerland, Karger, 2008. $212. 978-3-8055-8576-7 (cloth); 978-3-8055-8577-4 (e-book). New England Journal of Medicine. 360: 312-313. DOI: 10.1056/Nejmbkrev0807123  0.313
2008 Harmon B, Ratner L. Induction of the Galpha(q) signaling cascade by the human immunodeficiency virus envelope is required for virus entry. Journal of Virology. 82: 9191-205. PMID 18632858 DOI: 10.1128/Jvi.00424-08  0.628
2008 Salim A, Ratner L. Modulation of beta-catenin and E-cadherin interaction by Vpu increases human immunodeficiency virus type 1 particle release. Journal of Virology. 82: 3932-8. PMID 18256147 DOI: 10.1128/Jvi.00430-07  0.332
2008 Feng X, Ratner L. Human T-cell leukemia virus type 1 blunts signaling by interferon alpha. Virology. 374: 210-6. PMID 18234266 DOI: 10.1016/J.Virol.2007.12.036  0.424
2008 Cheng X, Belshan M, Ratner L. Hsp40 facilitates nuclear import of the human immunodeficiency virus type 2 Vpx-mediated preintegration complex. Journal of Virology. 82: 1229-37. PMID 18032501 DOI: 10.1128/Jvi.00540-07  0.412
2007 Bhatia AK, Campbell N, Panganiban A, Ratner L. Characterization of replication defects induced by mutations in the basic domain and C-terminus of HIV-1 matrix. Virology. 369: 47-54. PMID 17706261 DOI: 10.1016/J.Virol.2007.06.046  0.59
2007 Pontow S, Harmon B, Campbell N, Ratner L. Antiviral activity of a Rac GEF inhibitor characterized with a sensitive HIV/SIV fusion assay. Virology. 368: 1-6. PMID 17640696 DOI: 10.1016/J.Virol.2007.06.022  0.605
2007 Datta A, Silverman L, Phipps AJ, Hiraragi H, Ratner L, Lairmore MD. Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival. Retrovirology. 4: 49. PMID 17634129 DOI: 10.1186/1742-4690-4-49  0.483
2007 Ratner L, Grant C, Zimmerman B, Fritz J, Weil G, Denes A, Suresh R, Campbell N, Jacobson S, Lairmore M. Effect of treatment of Strongyloides infection on HTLV-1 expression in a patient with adult T-cell leukemia. American Journal of Hematology. 82: 929-31. PMID 17617788 DOI: 10.1002/Ajh.20929  0.461
2007 Ramos JC, Ruiz P, Ratner L, Reis IM, Brites C, Pedroso C, Byrne GE, Toomey NL, Andela V, Harhaj EW, Lossos IS, Harrington WJ. IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphoma. Blood. 109: 3060-8. PMID 17138822 DOI: 10.1182/Blood-2006-07-036368  0.355
2006 Michael B, Nair AM, Datta A, Hiraragi H, Ratner L, Lairmore MD. Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activity. Virology. 354: 225-39. PMID 16890266 DOI: 10.1016/J.Virol.2006.07.002  0.425
2006 Grant C, Oh U, Fugo K, Takenouchi N, Griffith C, Yao K, Newhook TE, Ratner L, Jacobson S. Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways. Plos Pathogens. 2: e33. PMID 16652169 DOI: 10.1371/Journal.Ppat.0020033  0.442
2006 Aboulafia DM, Ratner L, Miles SA, Harrington WJ. Antiviral and immunomodulatory treatment for AIDS-related primary central nervous system lymphoma: AIDS Malignancies Consortium pilot study 019. Clinical Lymphoma & Myeloma. 6: 399-402. PMID 16640817 DOI: 10.3816/Clm.2006.N.017  0.362
2006 Hiraragi H, Kim SJ, Phipps AJ, Silic-Benussi M, Ciminale V, Ratner L, Green PL, Lairmore MD. Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo. Journal of Virology. 80: 3469-76. PMID 16537614 DOI: 10.1128/Jvi.80.7.3469-3476.2006  0.45
2006 Mahnke LA, Belshan M, Ratner L. Analysis of HIV-2 Vpx by modeling and insertional mutagenesis. Virology. 348: 165-74. PMID 16457868 DOI: 10.1016/J.Virol.2005.12.023  0.361
2006 Pastore C, Nedellec R, Ramos A, Pontow S, Ratner L, Mosier DE. Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations. Journal of Virology. 80: 750-8. PMID 16378977 DOI: 10.1128/Jvi.80.2.750-758.2006  0.355
2006 Belshan M, Mahnke LA, Ratner L. Conserved amino acids of the human immunodeficiency virus type 2 Vpx nuclear localization signal are critical for nuclear targeting of the viral preintegration complex in non-dividing cells. Virology. 346: 118-26. PMID 16325220 DOI: 10.1016/J.Virol.2005.10.036  0.496
2006 Ramos JC, Ruiz P, Ratner L, Harjaj EW, Lossos I, Harrington WJ. IRF-4 and Interferon Resistance in Adult T-Cell Leukemia/Lymphoma. Blood. 108: 2531-2531. DOI: 10.1182/Blood.V108.11.2531.2531  0.419
2006 Ratner L, Bernal-Mizrachi L, Rauch D, Harding J, Gross S, Piwnica-Worms D. Bioluminescence Imaging of Spontaneous Lymphomas and Contribution of Distinct NFκB Pathways. Blood. 108: 2377-2377. DOI: 10.1182/Blood.V108.11.2377.2377  0.342
2005 Lairmore MD, Silverman L, Ratner L. Animal models for human T-lymphotropic virus type 1 (HTLV-1) infection and transformation. Oncogene. 24: 6005-15. PMID 16155607 DOI: 10.1038/Sj.Onc.1208974  0.442
2005 Gao L, Deng H, Zhao H, Hirbe A, Harding J, Ratner L, Weilbaecher K. HTLV-1 Tax transgenic mice develop spontaneous osteolytic bone metastases prevented by osteoclast inhibition. Blood. 106: 4294-302. PMID 16118323 DOI: 10.1182/Blood-2005-04-1730  0.329
2005 Ratner L. Pathogenesis and treatment of human T-cell leukemia virus infection. Immunologic Research. 32: 217-23. PMID 16106073 DOI: 10.1385/Ir:32:1-3:217  0.505
2005 Ratner L. Human T cell lymphotropic virus-associated leukemia/lymphoma. Current Opinion in Oncology. 17: 469-73. PMID 16093798 DOI: 10.1097/01.Cco.0000174037.84903.Fb  0.456
2005 Silverman LR, Phipps AJ, Montgomery A, Fernandez S, Tsukahara T, Ratner L, Lairmore MD. In vivo analysis of replication and immunogenicity of proviral clones of human T-lymphotropic virus type 1 with selective envelope surface-unit mutations. Blood. 106: 3602-8. PMID 16046523 DOI: 10.1182/Blood-2005-03-1076  0.443
2005 Wielgosz MM, Rauch DA, Jones KS, Ruscetti FW, Ratner L. Cholesterol dependence of HTLV-I infection. Aids Research and Human Retroviruses. 21: 43-50. PMID 15665643 DOI: 10.1089/Aid.2005.21.43  0.38
2004 Tsukahara T, Ratner L. Substitution of HIV Type 1 Nef with HTLV-1 p12. Aids Research and Human Retroviruses. 20: 938-43. PMID 15585081 DOI: 10.1089/Aid.2004.20.938  0.478
2004 Benko Z, Liang D, Agbottah E, Hou J, Chiu K, Yu M, Innis S, Reed P, Kabat W, Elder RT, Di Marzio P, Taricani L, Ratner L, Young PG, Bukrinsky M, et al. Anti-Vpr activity of a yeast chaperone protein. Journal of Virology. 78: 11016-29. PMID 15452222 DOI: 10.1128/Jvi.78.20.11016-11029.2004  0.475
2004 Ratner L. Adult T cell leukemia lymphoma. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2852-9. PMID 15353320 DOI: 10.2741/1442  0.478
2004 Mitra-Kaushik S, Harding J, Hess J, Schreiber R, Ratner L. Enhanced tumorigenesis in HTLV-1 tax-transgenic mice deficient in interferon-gamma. Blood. 104: 3305-11. PMID 15292059 DOI: 10.1182/Blood-2004-01-0266  0.335
2004 Pontow SE, Heyden NV, Wei S, Ratner L. Actin cytoskeletal reorganizations and coreceptor-mediated activation of rac during human immunodeficiency virus-induced cell fusion. Journal of Virology. 78: 7138-47. PMID 15194790 DOI: 10.1128/Jvi.78.13.7138-7147.2004  0.477
2004 Mitra-Kaushik S, Harding JC, Hess JL, Ratner L. Effects of the proteasome inhibitor PS-341 on tumor growth in HTLV-1 Tax transgenic mice and Tax tumor transplants. Blood. 104: 802-9. PMID 15090453 DOI: 10.1182/Blood-2003-11-3967  0.34
2004 Silverman LR, Phipps AJ, Montgomery A, Ratner L, Lairmore MD. Human T-cell lymphotropic virus type 1 open reading frame II-encoded p30II is required for in vivo replication: evidence of in vivo reversion. Journal of Virology. 78: 3837-45. PMID 15047799 DOI: 10.1128/Jvi.78.8.3837-3845.2004  0.431
2004 Kaushik R, Ratner L. Role of human immunodeficiency virus type 1 matrix phosphorylation in an early postentry step of virus replication. Journal of Virology. 78: 2319-26. PMID 14963128 DOI: 10.1128/Jvi.78.5.2319-2326.2004  0.436
2003 Feng X, Heyden NV, Ratner L. Alpha interferon inhibits human T-cell leukemia virus type 1 assembly by preventing Gag interaction with rafts. Journal of Virology. 77: 13389-95. PMID 14645593 DOI: 10.1128/Jvi.77.24.13389-13395.2003  0.482
2003 Belshan M, Ratner L. Identification of the nuclear localization signal of human immunodeficiency virus type 2 Vpx. Virology. 311: 7-15. PMID 12832198 DOI: 10.1016/S0042-6822(03)00093-X  0.44
2002 McGinn TM, Tao B, Cartner S, Schoeb T, Davis I, Ratner L, Fultz PN. Association of primate T-cell lymphotropic virus infection of pig-tailed macaques with high mortality. Virology. 304: 364-78. PMID 12504576 DOI: 10.1006/Viro.2002.1705  0.408
2002 Yang L, Ratner L. Interaction of HIV-1 gag and membranes in a cell-free system. Virology. 302: 164-73. PMID 12429525 DOI: 10.1006/Viro.2002.1532  0.324
2002 Smukler AJ, Ratner L. Hepatitis viruses and hepatocellular carcinoma in HIV-infected patients. Current Opinion in Oncology. 14: 538-42. PMID 12192274 DOI: 10.1097/00001622-200209000-00011  0.352
2002 Liu Y, Dole K, Stanley JR, Richard V, Rosol TJ, Ratner L, Lairmore M, Feuer G. Engraftment and tumorigenesis of HTLV-1 transformed T cell lines in SCID/bg and NOD/SCID mice. Leukemia Research. 26: 561-7. PMID 12007504 DOI: 10.1016/S0145-2126(01)00169-2  0.427
2002 McNearney T, Hornickova Z, Templeton A, Birdwell A, Arens M, Markham R, Saah A, Ratner L. Nef and LTR sequence variation from sequentially derived human immunodeficiency virus type 1 isolates. Virology. 208: 388-98. PMID 11831726 DOI: 10.1006/Viro.1995.1166  0.415
2001 Wang JJ, Sandefur S, Spearman P, Chiou CT, Chiang PH, Ratner L. Tracking the assembly pathway of human immunodeficiency virus type 1 Gag deletion mutants by immunogold labeling. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 9: 371-9. PMID 11759066 DOI: 10.1097/00129039-200112000-00014  0.423
2001 Pontow S, Ratner L. Evidence for common structural determinants of human immunodeficiency virus type 1 coreceptor activity provided through functional analysis of CCR5/CXCR4 chimeric coreceptors Journal of Virology. 75: 11503-11514. PMID 11689632 DOI: 10.1128/Jvi.75.23.11503-11514.2001  0.46
2001 Tsukahara T, Wielgosz MM, Ratner L. Characterization of envelope glycoprotein mutants for human T-cell leukemia virus type 1 infectivity and immortalization. Journal of Virology. 75: 9553-9. PMID 11533220 DOI: 10.1128/Jvi.75.19.9553-9559.2001  0.504
2001 Derdeyn CA, Decker JM, Sfakianos JN, Zhang Z, O'Brien WA, Ratner L, Shaw GM, Hunter E. Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. Journal of Virology. 75: 8605-14. PMID 11507206 DOI: 10.1128/Jvi.75.18.8605-8614.2001  0.435
2001 Zhou Y, Ratner L. A novel inducible expression system to study transdominant mutants of HIV-1 Vpr Virology. 287: 133-142. PMID 11504548 DOI: 10.1006/Viro.2001.1031  0.429
2001 Portis T, Harding JC, Ratner L. The contribution of NF-kappa B activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors. Blood. 98: 1200-8. PMID 11493471 DOI: 10.1182/Blood.V98.4.1200  0.409
2001 Poiesz BJ, Papsidero LD, Ehrlich G, Sherman M, Dube S, Poiesz M, Dillon K, Ruscetti FW, Slamon D, Fang C, Williams A, Duggan D, Glaser J, Gottlieb A, Goldberg J, ... Ratner L, et al. Prevalence of HTLV-I-associated T-cell lymphoma. American Journal of Hematology. 66: 32-8. PMID 11426489 DOI: 10.1002/1096-8652(200101)66:1<32::Aid-Ajh1004>3.0.Co;2-3  0.436
2001 Deora A, Ratner L. Viral protein U (Vpu)-mediated enhancement of human immunodeficiency virus type 1 particle release depends on the rate of cellular proliferation. Journal of Virology. 75: 6714-8. PMID 11413341 DOI: 10.1128/Jvi.75.14.6714-6718.2001  0.689
2001 Ratner L, Lee J, Tang S, Redden D, Hamzeh F, Herndier B, Scadden D, Kaplan L, Ambinder R, Levine A, Harrington W, Grochow L, Flexner C, Tan B, Straus D. Chemotherapy for human immunodeficiency virus-associated non-Hodgkin's lymphoma in combination with highly active antiretroviral therapy Journal of Clinical Oncology. 19: 2171-2178. PMID 11304769 DOI: 10.1200/Jco.2001.19.8.2171  0.385
2001 Wan JJ, Ratner L. Effects of mutant Vpr/Vpx on HIV-2 assembly demonstrated by immunoelectron microscopy Proceedings of the National Science Council, Republic of China. Part B, Life Sciences. 25: 50-58. PMID 11254173  0.384
2001 Jin L, Zhou Y, Ratner L. HIV type 2 Vpx interaction with Gag and incorporation into virus-like particles. Aids Research and Human Retroviruses. 17: 105-11. PMID 11177390 DOI: 10.1089/08892220150217193  0.324
2001 Portis T, Grossman WJ, Harding JC, Hess JL, Ratner L. Analysis of p53 inactivation in a human T-cell leukemia virus type 1 Tax transgenic mouse model. Journal of Virology. 75: 2185-93. PMID 11160722 DOI: 10.1128/Jvi.75.5.2185-2193.2001  0.398
2001 Ratner L, Portis T, Robek M, Harding J, Grossman W. Studies of the immortalizing activity of HTLV type 1 Tax, using an infectious molecular clone and transgenic mice. Aids Research and Human Retroviruses. 16: 1647-51. PMID 11080805 DOI: 10.1089/08892220050193092  0.688
2000 Robek MD, Ratner L. Immortalization of T lymphocytes by human T-cell leukemia virus type 1 is independent of the tax-CBP/p300 interaction. Journal of Virology. 74: 11988-92. PMID 11090202 DOI: 10.1128/Jvi.74.24.11988-11992.2000  0.741
2000 Levine AM, Li P, Cheung T, Tulpule A, Von Roenn J, Nathwani BN, Ratner L. Chemotherapy consisting of doxorubicin, bleomycin, vinblastine, and dacarbazine with granulocyte-colony-stimulating factor in HIV-infected patients with newly diagnosed Hodgkin's disease: A prospective, multi-institutional AIDS Clinical Trials Group Study (ACTG 149) Journal of Acquired Immune Deficiency Syndromes. 24: 444-450. PMID 11035615 DOI: 10.1097/00126334-200008150-00009  0.357
2000 Albrecht B, Collins ND, Burniston MT, Nisbet JW, Ratner L, Green PL, Lairmore MD. Human T-lymphotropic virus type 1 open reading frame I p12(I) is required for efficient viral infectivity in primary lymphocytes. Journal of Virology. 74: 9828-35. PMID 11024109 DOI: 10.1128/Jvi.74.21.9828-9835.2000  0.46
2000 Derdeyn CA, Decker JM, Sfakianos JN, Wu X, O'Brien WA, Ratner L, Kappes JC, Shaw GM, Hunter E. Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. Journal of Virology. 74: 8358-67. PMID 10954535 DOI: 10.1128/Jvi.74.18.8358-8367.2000  0.418
2000 Zhou Y, Ratner L. Phosphorylation of human immunodeficiency virus type 1 Vpr regulates cell cycle arrest Journal of Virology. 74: 6520-6527. PMID 10864665 DOI: 10.1128/Jvi.74.14.6520-6527.2000  0.433
2000 Pancio HA, Vander Heyden N, Kosuri K, Cresswell P, Ratner L. Interaction of human immunodeficiency virus type 2 Vpx and invariant chain. Journal of Virology. 74: 6168-72. PMID 10846101 DOI: 10.1128/Jvi.74.13.6168-6172.2000  0.475
2000 Pancio HA, Vander Heyden N, Ratner L. The C-terminal proline-rich tail of human immunodeficiency virus type 2 Vpx is necessary for nuclear localization of the viral preintegration complex in nondividing cells. Journal of Virology. 74: 6162-7. PMID 10846100 DOI: 10.1128/Jvi.74.13.6162-6167.2000  0.5
2000 Deora A, Spearman P, Ratner L. The N-terminal matrix domain of HIV-1 Gag is sufficient but not necessary for viral protein U-mediated enhancement of particle release through a membrane-targeting mechanism. Virology. 269: 305-12. PMID 10753709 DOI: 10.1006/Viro.1999.0094  0.684
2000 Voulgaropoulou F, Pontow SE, Ratner L. Productive infection of CD34+-cell-derived megakaryocytes by X4 and R5 HIV-1 isolates. Virology. 269: 78-85. PMID 10725200 DOI: 10.1006/Viro.2000.0193  0.405
2000 Pirounaki M, Heyden NA, Arens M, Ratner L. Rapid phenotypic drug susceptibility assay for HIV-1 with a CCR5 expressing indicator cell line. Journal of Virological Methods. 85: 151-61. PMID 10716348 DOI: 10.1016/S0166-0934(99)00163-9  0.432
2000 Trejo SR, Ratner L. The HTLV receptor is a widely expressed protein Virology. 268: 41-48. PMID 10683325 DOI: 10.1006/Viro.2000.0143  0.459
2000 Khanna KV, Yu XF, Ford DH, Ratner L, Hildreth JK, Markham RB. Differences among HIV-1 variants in their ability to elicit secretion of TNF-alpha. Journal of Immunology (Baltimore, Md. : 1950). 164: 1408-15. PMID 10640756 DOI: 10.4049/Jimmunol.164.3.1408  0.359
2000 Bartoe JT, Albrecht B, Collins ND, Robek MD, Ratner L, Green PL, Lairmore MD. Functional role of pX open reading frame II of human T-lymphotropic virus type 1 in maintenance of viral loads in vivo. Journal of Virology. 74: 1094-100. PMID 10627519 DOI: 10.1128/Jvi.74.3.1094-1100.2000  0.686
2000 Hung CS, Pontow S, Ratner L. Relationship between productive HIV-1 infection of macrophages and CCR5 utilization. Virology. 264: 278-88. PMID 10562492 DOI: 10.1006/Viro.1999.0013  0.382
1999 Collins ND, D'Souza C, Albrecht B, Robek MD, Ratner L, Ding W, Green PL, Lairmore MD. Proliferation response to interleukin-2 and Jak/Stat activation of T cells immortalized by human T-cell lymphotropic virus type 1 is independent of open reading frame I expression. Journal of Virology. 73: 9642-9. PMID 10516077 DOI: 10.1128/Jvi.73.11.9642-9649.1999  0.716
1999 Robek MD, Ratner L. Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone. Journal of Virology. 73: 4856-65. PMID 10233947 DOI: 10.1128/Jvi.73.6.4856-4865.1999  0.733
1999 Wang JJ, Horton R, Varthakavi V, Spearman P, Ratner L. Formation and release of virus-like particles by HIV-1 matrix protein [1] Aids. 13: 281-283. PMID 10202836 DOI: 10.1097/00002030-199902040-00018  0.385
1999 Vocero-Akbani AM, Heyden NV, Lissy NA, Ratner L, Dowdy SF. Killing HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein. Nature Medicine. 5: 29-33. PMID 9883836 DOI: 10.1038/4710  0.422
1999 Grossman WJ, Verbsky JW, Yang L, Berg LJ, Fields LE, Chaplin DD, Ratner L. Dysregulated Myelopoiesis in Mice Lacking Jak3 Blood. 94: 932-939. DOI: 10.1182/Blood.V94.3.932.415K30_932_939  0.312
1999 Voulgaropoulou F, Tan B, Soares M, Hahn B, Ratner L. Distinct Human Immunodeficiency Virus Strains in the Bone Marrow Are Associated with the Development of Thrombocytopenia Journal of Virology. 73: 3497-3504. DOI: 10.1128/Jvi.73.4.3497-3504.1999  0.447
1999 Hung C, Vander Heyden N, Ratner L. Analysis of the Critical Domain in the V3 Loop of Human Immunodeficiency Virus Type 1 gp120 Involved in CCR5 Utilization Journal of Virology. 73: 8216-8226. DOI: 10.1128/Jvi.73.10.8216-8226.1999  0.442
1999 Ratner L, Redden D, Hamzeh F, Levine A, Harrington W, Scadden D, Kaplan L, Ambinder R, Grochow L, Flexner C, Tan B, Straus D. CHEMOTHERAPY FOR HIV-ASSOCIATED NON-HODGKIN LYMPHOMA (HIV-NHL) IN COMBINATION WITH HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) IS NOT ASSOCIATED WITH EXCESSIVE TOXICITY. Jaids: Journal of Acquired Immune Deficiency Syndromes. 21: A32. DOI: 10.1097/00126334-199905010-00112  0.359
1999 Robek MD, Ratner L. ROLE OF TAX ACTIVATION OF CELLULAR PROMOTERS IN IMMORTALIZATION OF T-LYMPHOCYTES BY HTLV-I Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 20: A34. DOI: 10.1097/00042560-199904010-00122  0.68
1998 Albrecht B, Collins ND, Newbound GC, Ratner L, Lairmore MD. Quantification of human T-cell lymphotropic virus type 1 proviral load by quantitative competitive polymerase chain reaction. Journal of Virological Methods. 75: 123-40. PMID 9870588 DOI: 10.1016/S0166-0934(98)00087-1  0.445
1998 Collins ND, Newbound GC, Albrecht B, Beard JL, Ratner L, Lairmore MD. Selective ablation of human T-cell lymphotropic virus type 1 p12I reduces viral infectivity in vivo. Blood. 91: 4701-7. PMID 9616168 DOI: 10.1182/Blood.V91.12.4701.412K23_4701_4707  0.46
1998 Popov S, Rexach M, Ratner L, Blobel G, Bukrinsky M. Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex. The Journal of Biological Chemistry. 273: 13347-52. PMID 9582382 DOI: 10.1074/Jbc.273.21.13347  0.407
1998 Pancio HA, Ratner L. Human immunodeficiency virus type 2 Vpx-Gag interaction Journal of Virology. 72: 5271-5275. PMID 9573303 DOI: 10.1128/Jvi.72.6.5271-5275.1998  0.442
1998 Garnier L, Ratner L, Rovinski B, Cao SX, Wills JW. Particle size determinants in the human immunodeficiency virus type 1 Gag protein. Journal of Virology. 72: 4667-77. PMID 9573230 DOI: 10.1128/Jvi.72.6.4667-4677.1998  0.373
1998 Robek MD, Wong FH, Ratner L. Human T-cell leukemia virus type 1 pX-I and pX-II open reading frames are dispensable for the immortalization of primary lymphocytes. Journal of Virology. 72: 4458-62. PMID 9557741 DOI: 10.1128/Jvi.72.5.4458-4462.1998  0.744
1998 Zhou Y, Lu Y, Ratner L. Arginine residues in the C-terminus of HIV-1 Vpr are important for nuclear localization and cell cycle arrest Virology. 242: 414-424. PMID 9514978 DOI: 10.1006/Viro.1998.9028  0.424
1998 Popov S, Rexach M, Zybarth G, Reiling N, Lee MA, Ratner L, Lane CM, Moore MS, Blobel G, Bukrinsky M. Viral protein R regulates nuclear import of the HIV-1 pre-integration complex. The Embo Journal. 17: 909-17. PMID 9463369 DOI: 10.1093/Emboj/17.4.909  0.448
1997 Trejo SR, Fahl WE, Ratner L. The tax protein of human T-cell leukemia virus type 1 mediates the transactivation of the c-sis/platelet-derived growth factor-B promoter through interactions with the zinc finger transcription factors Sp1 and NGFI-A/Egr-1. The Journal of Biological Chemistry. 272: 27411-21. PMID 9341193 DOI: 10.1074/Jbc.272.43.27411  0.379
1997 Tan B, Ratner L. The use of new antiretroviral therapy in combination with chemotherapy Current Opinion in Oncology. 9: 455-464. PMID 9327224 DOI: 10.1097/00001622-199709050-00010  0.391
1997 Spearman P, Horton R, Ratner L, Kuli-Zade I. Membrane binding of human immunodeficiency virus type 1 matrix protein in vivo supports a conformational myristyl switch mechanism Journal of Virology. 71: 6582-6592. PMID 9261380 DOI: 10.1128/Jvi.71.9.6582-6592.1997  0.311
1997 Grossman WJ, Ratner L. Cytokine expression and tumorigenicity of large granular lymphocytic leukemia cells from mice transgenic for the Tax gene of human T-cell leukemia virus type I Blood. 90: 783-794. PMID 9226179 DOI: 10.1182/Blood.V90.2.783.783_783_794  0.422
1996 Spearman P, Ratner L. Human immunodeficiency virus type 1 capsid formation in reticulocyte lysates Journal of Virology. 70: 8187-8194. PMID 8892951 DOI: 10.1128/Jvi.70.11.8187-8194.1996  0.442
1996 Grossman WJ, Ratner L. Transgenic mouse models for HTLV-I infection Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 13. PMID 8797719 DOI: 10.1097/00042560-199600001-00025  0.447
1996 Collins ND, Newbound GC, Ratner L, Lairmore MD. In vitro CD4+ lymphocyte transformation and infection in a rabbit model with a molecular clone of human T-cell lymphotropic virus type 1 Journal of Virology. 70: 7241-7246. PMID 8794375 DOI: 10.1128/Jvi.70.10.7241-7246.1996  0.431
1996 Trejo SR, Fahl WE, Ratner L. c-sis/PDGF-B promoter transactivation by the Yax protein of human T-cell leukemia virus type 1. The Journal of Biological Chemistry. 271: 14584-90. PMID 8662878 DOI: 10.1074/Jbc.271.24.14584  0.408
1996 Carrillo A, Ratner L. Cooperative effects of the human immunodeficiency virus type 1 envelope variable loops V1 and V3 in mediating infectivity for T cells Journal of Virology. 70: 1310-1316. PMID 8551601 DOI: 10.1128/Jvi.70.2.1310-1316.1996  0.466
1996 Carrillo A, Ratner L. Human immunodeficiency virus type 1 tropism for T-lymphoid cell lines: Role of the V3 loop and C4 envelope determinants Journal of Virology. 70: 1301-1309. PMID 8551600 DOI: 10.1128/Jvi.70.2.1301-1309.1996  0.419
1996 Ebenbichler C, McNearney T, Stoiber H, Möst J, Zangerle R, Vogetseder W, Patsch JR, Ratner L, Dierich MP. Sera from HIV-1 infected individuals in all stages of disease preferentially recognize the V3 loop of the prototypic macrophage-tropic glycoprotein gp120 ADA. Molecular Immunology. 32: 1039-45. PMID 8544853 DOI: 10.1016/0161-5890(95)00083-6  0.397
1996 Yahi N, Ratner L, Harouse JM, González-Scarano F, Fantini J. Genetic determinants controlling HIV-1 tropism for CD4−/GalCer+ human intestinal epithelial cells Perspectives in Drug Discovery and Design. 5: 161-168. DOI: 10.1007/Bf02174011  0.453
1995 Bandres JC, Shaw AS, Ratner L. HIV-1 Nef protein downregulation of CD4 surface expression: relevance of the lck binding domain of CD4. Virology. 207: 338-41. PMID 7871751 DOI: 10.1006/Viro.1995.1089  0.309
1995 Grossman WJ, Kimata JT, Wong FH, Zutter M, Ley TJ, Ratner L. Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I Proceedings of the National Academy of Sciences of the United States of America. 92: 1057-1061. PMID 7862633 DOI: 10.1073/Pnas.92.4.1057  0.48
1995 Lu YL, Bennett RP, Wills JW, Gorelick R, Ratner L. A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particles. Journal of Virology. 69: 6873-9. PMID 7474102 DOI: 10.1128/Jvi.69.11.6873-6879.1995  0.453
1994 Murti KG, Brown PS, Ratner L, Garcia JV. Highly localized tracks of human immunodeficiency virus type 1 Nef in the nucleus of cells of a human CD4+ T-cell line. Proceedings of the National Academy of Sciences of the United States of America. 90: 11895-9. PMID 8265644 DOI: 10.1073/Pnas.90.24.11895  0.427
1994 Bandres JC, Luria S, Ratner L. Regulation of Human Immunodeficiency Virus Nef Protein by Phosphorylation Virology. 201: 157-161. PMID 8178481 DOI: 10.1006/Viro.1994.1278  0.429
1994 Bandres JC, Ratner L. Human immunodeficiency virus type 1 nef protein down-regulates transcription factors NF-κB and AP-1 in human T cells in vitro after T-cell receptor stimulation Journal of Virology. 68: 3243-3249. PMID 8151786 DOI: 10.1128/Jvi.68.5.3243-3249.1994  0.449
1994 Spearman P, Wang JJ, Vander Heyden N, Ratner L. Identification of human immunodeficiency virus type 1 gag protein domains essential to membrane binding and particle assembly Journal of Virology. 68: 3232-3242. PMID 8151785 DOI: 10.1128/Jvi.68.5.3232-3242.1994  0.381
1994 Horton R, Spearman P, Ratner L. HIV-2 viral protein X association with the Gag p27 capsid protein Virology. 199: 453-457. PMID 8122374 DOI: 10.1006/Viro.1994.1144  0.447
1994 Paine E, Gu R, Ratner L. Structure and expression of the human T-cell leukemia virus type 1 envelope protein Virology. 199: 331-338. PMID 8122365 DOI: 10.1006/Viro.1994.1131  0.443
1994 Heinzinger NK, Bukrinsky MI, Haggerty SA, Ragland AM, Kewalramani V, Lee MA, Gendelman HE, Ratner L, Stevenson M, Emerman M. The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 7311-5. PMID 8041786 DOI: 10.1073/Pnas.91.15.7311  0.491
1994 Kimata JT, Wong FH, Wang JJ, Ratner L. Construction and characterization of infectious human T-cell leukemia virus type 1 molecular clones. Virology. 204: 656-64. PMID 7941334 DOI: 10.1006/Viro.1994.1581  0.49
1994 Yu X, Mclane MF, Ratner L, O'Brien W, Collman R, Essex M, Lee TH. Killing of primary CD4+ T cells by non-syncytium-inducing macrophage-tropic human immunodeficiency virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 91: 10237-10241. PMID 7937869 DOI: 10.1073/Pnas.91.21.10237  0.465
1994 Wang JJ, Lu LY, Ratner L. Particle assembly and Vpr expression in human immunodeficiency virus type 1-infected cells demonstrated by immunoelectron microscopy Journal of General Virology. 75: 2607-2614. PMID 7931147 DOI: 10.1099/0022-1317-75-10-2607  0.486
1994 Kimata JT, Wong FH, Ratner L. CD3-dependent lymphocyte activation by human T cell leukaemia virus type I-producing T cells Journal of General Virology. 75: 2433-2437. PMID 7915756 DOI: 10.1099/0022-1317-75-9-2433  0.43
1994 Arens M, Joseph T, Nag S, Miller JP, Powderly WG, Ratner L. Alterations in spliced and unspliced HIV-1-specific RNA detection in peripheral blood mononuclear cells of individuals with varying CD4-positive lymphocyte counts. Aids Research and Human Retroviruses. 9: 1257-63. PMID 7908212 DOI: 10.1089/Aid.1993.9.1257  0.396
1994 Lilenbaum RC, Ratner L. Systemic treatment of Kaposi's sarcoma: Current status and future directions Aids. 8: 141-151. PMID 7519018 DOI: 10.1097/00002030-199402000-00001  0.338
1993 Ebenbichler CF, Röder C, Vornhagen R, Ratner L, Dierich MP. Cell surface proteins binding to recombinant soluble HIV-1 and HIV-2 transmembrane proteins. Aids (London, England). 7: 489-95. PMID 8507415 DOI: 10.1097/00002030-199304000-00006  0.382
1993 Niederman TM, Hastings WR, Luria S, Bandres JC, Ratner L. HIV-1 Nef protein inhibits the recruitment of AP-1 DNA-binding activity in human T-cells. Virology. 194: 338-44. PMID 8480425 DOI: 10.1006/Viro.1993.1264  0.482
1993 McNearney T, Hornickova Z, Kloster B, Birdwell A, Storch GA, Polmar SH, Arens M, Ratner L. Evolution of sequence divergence among human immunodeficiency virus type 1 isolates derived from a blood donor and a recipient. Pediatric Research. 33: 36-42. PMID 8433858 DOI: 10.1203/00006450-199301000-00008  0.399
1993 Lu YL, Spearman P, Ratner L. Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions. Journal of Virology. 67: 6542-50. PMID 8411357 DOI: 10.1128/Jvi.67.11.6542-6550.1993  0.482
1993 Ratner L, Vander Heyden N. Mechanism of action of N-butyl deoxynojirimycin in inhibiting HIV-1 infection and activity in combination with nucleoside analogs Aids Research and Human Retroviruses. 9: 291-297. PMID 8390276 DOI: 10.1089/Aid.1993.9.291  0.39
1993 Gu R, Westervelt P, Ratner L. Role of HIV-1 envelope V3 loop cleavage in cell tropism Aids Research and Human Retroviruses. 9: 1007-1015. PMID 8280475 DOI: 10.1089/Aid.1993.9.1007  0.433
1993 Carrillo A, Trowbridge DB, Westervelt P, Ratner L. Identification of HIV1 determinants for T lymphoid cell line infection. Virology. 197: 817-24. PMID 8249306 DOI: 10.1006/Viro.1993.1664  0.479
1993 Niederman TM, Hastings WR, Ratner L. Myristoylation-enhanced binding of the HIV-1 Nef protein to T cell skeletal matrix. Virology. 197: 420-5. PMID 8212577 DOI: 10.1006/Viro.1993.1605  0.389
1993 Kimata JT, Palker TJ, Ratner L. The mitogenic activity of human T-cell leukemia virus type I is T-cell associated and requires the CD2/LFA-3 activation pathway Journal of Virology. 67: 3134-3141. PMID 7684460 DOI: 10.1128/Jvi.67.6.3134-3141.1993  0.483
1993 Ebenbichler C, Westervelt P, Carrillo A, Henkel T, Johnson D, Ratner L. Structure—function relationships of the HIV-1 envelope V3 loop tropism determinant Aids. 7: 639-646. DOI: 10.1097/00002030-199305000-00005  0.429
1993 Ratner L. HIV life cycle and genetic approaches Perspectives in Drug Discovery and Design. 1: 3-22. DOI: 10.1007/Bf02171653  0.465
1993 Ratner L. Molecular biology and pathogenesis of HIV infection Current Opinion in Infectious Diseases. 6: 181-190.  0.359
1992 Dedera D, Gu R, Ratner L. Conserved cysteine residues in the human immunodeficiency virus type 1 transmembrane envelope protein are essential for precursor envelope cleavage Journal of Virology. 66: 1207-1209. PMID 1731099 DOI: 10.1128/Jvi.66.2.1207-1209.1992  0.434
1992 Bryant ML, Ratner L. Biology and molecular biology of human immunodeficiency virus Pediatric Infectious Disease Journal. 11: 390-400. PMID 1630860 DOI: 10.1097/00006454-199205000-00010  0.383
1992 Niederman TMJ, Ratner L. Functional analysis of HIV1 and SIV Nef proteins Research in Virology. 143: 43-46. PMID 1565854 DOI: 10.1016/S0923-2516(06)80077-4  0.357
1992 Westervelt P, Trowbridge DB, Epstein LG, Blumberg BM, Li Y, Hahn BH, Shaw GM, Price RW, Ratner L. Macrophage tropism determinants of human immunodeficiency virus type 1 in vivo Journal of Virology. 66: 2577-2582. PMID 1548783 DOI: 10.1128/Jvi.66.4.2577-2582.1992  0.422
1992 Ratner L. Glucosidase inhibitors for treatment of HIV-1 infection Aids Research and Human Retroviruses. 8: 165-173. PMID 1540404 DOI: 10.1089/Aid.1992.8.165  0.424
1992 Westervelt P, Henkel T, Trowbridge DB, Orenstein J, Heuser J, Gendelman HE, Ratner L. Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants. Journal of Virology. 66: 3925-31. PMID 1533883 DOI: 10.1128/Jvi.66.6.3925-3931.1992  0.446
1992 McNearney T, Hornickova Z, Markham R, Birdwell A, Arens M, Saah A, Ratner L. Relationship of human immunodeficiency virus type 1 sequence heterogeneity to stage of disease. Proceedings of the National Academy of Sciences of the United States of America. 89: 10247-51. PMID 1438212 DOI: 10.1073/Pnas.89.21.10247  0.407
1992 Westervelt P, Henkel T, Trowbridge DB, Orenstein J, Heuser J, Gendelman HE, Ratner L. Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants. Journal of Virology. 66: 3925-3931. DOI: 10.1128/jvi.66.6.3925-3931.1992  0.301
1992 Niederman TM, Garcia JV, Hastings WR, Luria S, Ratner L. Human immunodeficiency virus type 1 Nef protein inhibits NF-kappa B induction in human T cells. Journal of Virology. 66: 6213-6219. DOI: 10.1128/Jvi.66.10.6213-6219.1992  0.454
1992 Dedera DA, Gu R, Ratner L. Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function Virology. 187: 383-387. DOI: 10.1016/0042-6822(92)90331-I  0.479
1991 Kimata JT, Ratner L. Temporal regulation of viral and cellular gene expression during human T-lymphotropic virus type I-mediated lymphocyte immortalization Journal of Virology. 65: 4398-4407. PMID 2072456 DOI: 10.1128/Jvi.65.8.4398-4407.1991  0.411
1991 Niederman TMJ, Hu W, Ratner L. Simian immunodeficiency virus negative factor suppresses the level of viral mRNA in COS cells Journal of Virology. 65: 3538-3546. PMID 2041081 DOI: 10.1128/Jvi.65.7.3538-3546.1991  0.468
1991 Paine E, Garcia J, Philpott TC, Shaw G, Ratner L. Limited sequence variation in human T-lymphotropic virus type 1 isolates from North American and African patients. Virology. 182: 111-23. PMID 2024459 DOI: 10.1016/0042-6822(91)90654-T  0.328
1991 Westervelt P, Gendelman HE, Ratner L. Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes Proceedings of the National Academy of Sciences of the United States of America. 88: 3097-3101. PMID 2014229 DOI: 10.1073/Pnas.88.8.3097  0.406
1991 Bryant ML, Ratner L, Duronio RJ, Kishore NS, Devadas B, Adams SP, Gordon JI. Incorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell line. Proceedings of the National Academy of Sciences of the United States of America. 88: 2055-9. PMID 2006142 DOI: 10.1073/Pnas.88.6.2055  0.462
1991 Ratner L, Vander Heyden N, Garcia J, Polinsky M, Westervelt P, Becich M. Formation of noninfectious HIV-1 virus particles lacking a full-length envelope protein Aids Research and Human Retroviruses. 7: 287-294. PMID 1829617 DOI: 10.1089/Aid.1991.7.287  0.427
1991 Ratner L, Philpott T, Trowbridge DB. Nucleotide sequence analysis of isolates of human T-lymphotropic virus type 1 of diverse geographical origins Aids Research and Human Retroviruses. 7: 923-941. PMID 1760230 DOI: 10.1089/Aid.1991.7.923  0.353
1991 Dedera D, Ratner L. Demonstration of two distinct cytopathic effects with syncytium formation-defective human immunodeficiency virus type 1 mutants Journal of Virology. 65: 6129-6136. PMID 1717715 DOI: 10.1128/Jvi.65.11.6129-6136.1991  0.478
1991 Ratner L, Heyden NV, Dedera D. Inhibition of HIV and SIV infectivity by blockade of α-glucosidase activity Virology. 181: 180-192. PMID 1704656 DOI: 10.1016/0042-6822(91)90483-R  0.457
1990 Bryant M, Ratner L. Myristoylation-dependent replication and assembly of human immunodeficiency virus 1 Proceedings of the National Academy of Sciences of the United States of America. 87: 523-527. PMID 2405382 DOI: 10.1073/Pnas.87.2.523  0.472
1990 Dedera D, Vander Heyden N, Ratner L. Attenuation of HIV-1 infectivity by an inhibitor of oligosaccharide processing Aids Research and Human Retroviruses. 6: 785-794. PMID 2364019 DOI: 10.1089/Aid.1990.6.785  0.433
1990 McNearney T, Westervelt P, Thielan BJ, Trowbridge DB, Garcia J, Whittier R, Ratner L. Limited sequence heterogeneity among biologically distinct human immunodeficiency virus type 1 isolates from individuals involved in a clustered infectious outbreak. Proceedings of the National Academy of Sciences of the United States of America. 87: 1917-21. PMID 2308953 DOI: 10.1073/Pnas.87.5.1917  0.351
1990 Griffith RC, Saha BK, Janney CM, Ratner L, Brunt EM, Gajl-Peczalska KJ, Hanto DW. Immunoblastic lymphoma of T-cell type in a chronically immunosuppressed renal transplant recipient. American Journal of Clinical Pathology. 93: 280-5. PMID 2301290 DOI: 10.1093/Ajcp/93.2.280  0.426
1990 Ratner L, Vander Heyden N, Paine E, Frei-Lahr D, Brown R, Petruska P, Reddy S, Lairmore MD. Familial adult T-cell leukemia/lymphoma American Journal of Hematology. 34: 215-222. PMID 2194393 DOI: 10.1002/Ajh.2830340312  0.452
1989 Bryant ML, Heuckeroth RO, Kimata JT, Ratner L, Gordon JI. Replication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acid Proceedings of the National Academy of Sciences of the United States of America. 86: 8655-8659. PMID 2813417 DOI: 10.1073/Pnas.86.22.8655  0.418
1989 Lee SJ, Hu W, Fisher AG, Looney DJ, Kao VF, Mitsuya H, Ratner L, Wong-Staal F. Role of the carboxy-terminal portion of the HIV-1 transmembrane protein in viral transmission and cytopathogenicity. Aids Research and Human Retroviruses. 5: 441-9. PMID 2788444 DOI: 10.1089/Aid.1989.5.441  0.458
1989 Niederman TM, Thielan BJ, Ratner L. Human immunodeficiency virus type 1 negative factor is a transcriptional silencer. Proceedings of the National Academy of Sciences of the United States of America. 86: 1128-32. PMID 2784001 DOI: 10.1073/Pnas.86.4.1128  0.426
1989 Ratner L. Regulation of expression of the c-sis proto-oncogene Nucleic Acids Research. 17: 4101-4115. PMID 2740212 DOI: 10.1093/Nar/17.11.4101  0.323
1989 Bell J, Ratner L. Specificity of polymerase chain amplification reactions for human immunodeficiency virus type DNA sequences Aids Research and Human Retroviruses. 5: 87-95. PMID 2655672 DOI: 10.1089/Aid.1989.5.87  0.399
1989 Ratner L. Measurement of human immunodeficiency virus load and its relation to disease progression Aids Research and Human Retroviruses. 5: 115-119. PMID 2653388 DOI: 10.1089/Aid.1989.5.115  0.344
1989 Vander Heyden N, Rodi C, Ratner L. Analogs of 3'-amino-3'-deoxyadenosine inhibit HIV-1 replication Aids Research and Human Retroviruses. 5: 647-653. PMID 2611044 DOI: 10.1089/Aid.1989.5.647  0.443
1989 Hu W, Heyden NV, Ratner L. Analysis of the function of viral protein X (VPX) of HIV-2 Virology. 173: 624-630. PMID 2596032 DOI: 10.1016/0042-6822(89)90574-6  0.509
1989 Dedera D, Hu W, Vander Heyden N, Ratner L. Viral protein R of human immunodeficiency virus types 1 and 2 is dispensable for replication and cytopathogenicity in lymphoid cells. Journal of Virology. 63: 3205-3208. DOI: 10.1128/Jvi.63.7.3205-3208.1989  0.467
1989 Ratner L. Human immunodeficiency virus-associated thrombocytopenic purpura. The reply The American Journal of Medicine. 87: 245. DOI: 10.1016/S0002-9343(89)80717-X  0.398
1988 RATNER L, POIESZ BJ. Leukemias Associated with Human T-Cell Lymphotropic Virus Type I in a Non-Endemic Region Medicine. 67: 401. DOI: 10.1097/00005792-198811000-00004  0.445
1987 Thielan BJ, Hunter E, Desrosiers RC, Ratner L. Trans-activation of long terminal repeat sequence-mediated gene expression is not a property of type D retrovirus replication. The Journal of General Virology. 2265-70. PMID 3612091 DOI: 10.1099/0022-1317-68-8-2265  0.416
1987 Ratner L, Polmar SH, Paul N, Ruddle N. Cytotoxic factors secreted by cells infected by human immunodeficiency virus type I. Aids Research and Human Retroviruses. 3: 147-55. PMID 3497655 DOI: 10.1089/Aid.1987.3.147  0.487
1987 Fisher AG, Ensoli B, Ivanoff L, Chamberlain M, Petteway S, Ratner L, Gallo RC, Wong-Staal F. The sor gene of HIV-1 is required for efficient virus transmission in vitro. Science. 237: 888-893. PMID 3497453 DOI: 10.1126/Science.3497453  0.498
1987 Ratner L, Fisher A, Jagodzinski LL, Liou RS, Mitsuya H, Gallo RC, Wong-Staal F. Complete nucleotide sequences of functional clones of the virus associated with the acquired immunodeficiency syndrome, HTLV-III/LAV. Haematology and Blood Transfusion. 31: 404-406. PMID 3443402 DOI: 10.1007/978-3-642-72624-8_86  0.474
1987 Ratner L, Fisher A, Jagodzinski LL, Mitsuya H, Liou RS, Gallo RC, Wong-Staal F. Complete nucleotide sequences of functional clones of the AIDS virus. Aids Research and Human Retroviruses. 3: 57-69. PMID 3040055 DOI: 10.1089/Aid.1987.3.57  0.43
1987 Ratner L, Griffith RC, Marselle L, Hoh M, Wong-Staal F, Saxinger C. A lymphoproliferative disorder caused by human T-lymphotropic virus type I. Demonstration of a continuum between acute and chronic adult T-cell leukemia/lymphoma. The American Journal of Medicine. 83: 953-958. PMID 2890302 DOI: 10.1016/0002-9343(87)90658-9  0.423
1986 Ratner L, Peylan-Ramu N, Wesley R, Poplack DG. Adverse prognostic influence of hepatitis B virus infection in acute lymphoblastic leukemia. Cancer. 58: 1096-1100. PMID 3460683 DOI: 10.1002/1097-0142(19860901)58:5<1096::Aid-Cncr2820580519>3.0.Co;2-B  0.323
1986 Fisher AG, Ratner L, Mitsuya H, Marselle LM, Harper ME, Broder S, Gallo RC, Wong-Staal F. Infectious mutants of HTLV-III with changes in the 3' region and markedly reduced cytopathic effects. Science (New York, N.Y.). 233: 655-9. PMID 3014663 DOI: 10.1126/Science.3014663  0.474
1986 Seigel LJ, Ratner L, Josephs SF, Derse D, Feinberg MB, Reyes GR, O'Brien SJ, Wong-Staal F. Transactivation induced by human T-lymphotropic virus type III (HTLV III) maps to a viral sequence encoding 58 amino acids and lacks tissue specificity. Virology. 148: 226-31. PMID 3002031 DOI: 10.1016/0042-6822(86)90419-8  0.382
1985 Ratner L, Starcich B, Josephs SF, Hahn BH, Reddy EP, Livak KJ, Petteway SR, Pearson ML, Haseltine WA, Arya SK. Polymorphism of the 3' open reading frame of the virus associated with the acquired immune deficiency syndrome, human T-lymphotropic virus type III. Nucleic Acids Research. 13: 8219-29. PMID 2999715 DOI: 10.1093/Nar/13.22.8219  0.409
1985 Ratner L, Josephs SF, Jarrett R, Reitz MS, Wong-Staal F. Nucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factor. Nucleic Acids Research. 13: 5007-18. PMID 2991848 DOI: 10.1093/Nar/13.14.5007  0.337
1985 Ratner L, Gallo RC, Wong-Staal F. HTLV-III, LAV, ARV are variants of same AIDS virus [8] Nature. 313: 636-637. PMID 2983217 DOI: 10.1038/313636C0  0.398
1985 Starcich B, Ratner L, Josephs SF, Okamoto T, Gallo RC, Wong-Staal F. Characterization of long terminal repeat sequences of HTLV-III. Science (New York, N.Y.). 227: 538-40. PMID 2981438 DOI: 10.1126/Science.2981438  0.304
1985 Ratner L, Haseltine W, Patarca R, Livak KJ, Starcich B, Josephs SF, Doran ER, Rafalski JA, Whitehorn EA, Baumeister K. Complete nucleotide sequence of the AIDS virus, HTLV-III. Nature. 313: 277-84. PMID 2578615 DOI: 10.1038/313277A0  0.369
1985 Fisher AG, Collalti E, Ratner L, Gallo RC, Wong-Staal F. A molecular clone of HTLV-III with biological activity. Nature. 316: 262-5. PMID 2410792 DOI: 10.1038/316262A0  0.449
1985 Ratner L, Josephs SF, Starcich B, Hahn B, Shaw GM, Gallo RC, Wong-Staal F. Nucleotide sequence analysis of a variant human T-cell leukemia virus (HTLV-Ib) provirus with a deletion in pX-I. Journal of Virology. 54: 781-790. DOI: 10.1128/Jvi.54.3.781-790.1985  0.453
1985 Wong-Staal F, Ratner L, Shaw G, Hahn B, Harper M, Franchini G, Gallo R. Molecular Biology of Human T-Lymphotropic Retroviruses Cancer Research. 45: 293-304. DOI: 10.1007/978-1-4684-5242-6_24  0.439
1984 Clarke MF, Westin E, Schmidt D, Josephs SF, Ratner L, Wong-Staal F, Gallo RC, Reitz MS. Transformation of NIH 3T3 cells by a human c-sis cDNA clone. Nature. 308: 464-7. PMID 6323994 DOI: 10.1038/308464A0  0.425
1984 Josephs SF, Guo C, Ratner L, Wong-Staal F. Human-proto-oncogene nucleotide sequences corresponding to the transforming region of simian sarcoma virus. Science (New York, N.Y.). 223: 487-91. PMID 6318322 DOI: 10.1126/Science.6318322  0.302
1980 Ratner L, Nordlund JJ, Lengyel P. Interferon as an inhibitor of cell growth: studies with mouse melanoma cells. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 163: 267-72. PMID 7360756 DOI: 10.3181/00379727-163-40760  0.316
1978 Jarvis AP, White C, Ball A, Gupta SL, Ratner L, Sen GC, Colby C. Interferon-associated, dsRNA-dependent enzyme activities in a mutant 3T6 cell engaged in the semiconstitutive synthesis of interferon Cell. 14: 879-887. PMID 688397 DOI: 10.1016/0092-8674(78)90343-4  0.407
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