| Year |
Citation |
Score |
| 2023 |
Waldron C, Eifert J, O'Keefe S, Williams R, Le T. Delmopinol hydrochloride inhibits Campylobacter jejuni on skinless poultry meat, stainless steel and high-density polyethylene food contact surfaces. Letters in Applied Microbiology. PMID 37019823 DOI: 10.1093/lambio/ovad042 |
0.324 |
|
| 2023 |
Cummins TL, Doré V, Feizpour A, Krishnadas N, Bourgeat P, Elias A, Lamb F, Williams R, Hopwood MJ, Landau S, Villemagne V, Weiner M, Rowe CC. Tau, β-amyloid, and glucose metabolism following service-related Traumatic Brain Injury in Vietnam war veterans: The AIBL-VETS study. Journal of Neurotrauma. PMID 36855333 DOI: 10.1089/neu.2022.0172 |
0.32 |
|
| 2022 |
Madadi Y, Sun J, Chen H, Williams R, Yousefi S. Detecting Retinal Neural and Stromal Cell Classes and Ganglion Cell Subtypes Based on Transcriptome Data with Deep Transfer Learning. Bioinformatics (Oxford, England). PMID 35876552 DOI: 10.1093/bioinformatics/btac514 |
0.315 |
|
| 2022 |
Delanerolle G, Williams R, Stipancic A, Byford R, Forbes A, Anand S, Bradley D, Tsang R, Murphy S, Akbari A, Bedston S, Lyons R, Owen R, Beggs J, Chuter A, et al. Methodological issues for using a common data model (CDM) of COVID-19 vaccine uptake and important adverse events of interest (AEIs): the Data and Connectivity COVID-19 Vaccines Pharmacovigilance (DaC-VaP) United Kingdom feasibility study. Jmir Formative Research. PMID 35786634 DOI: 10.2196/37821 |
0.32 |
|
| 2021 |
Rex MR, Williams R, Birsoy K, Ta Llman MS, Stahl M. Targeting mitochondrial metabolism in acute myeloid leukemia. Leukemia & Lymphoma. 1-8. PMID 34704521 DOI: 10.1080/10428194.2021.1992759 |
0.342 |
|
| 2021 |
El-Desoky AHH, Inada N, Maeyama Y, Kato H, Hitora Y, Sebe M, Nagaki M, Kai A, Eguchi K, Inazumi T, Sugimoto Y, Frisvad JC, Williams RM, Tsukamoto S. Taichunins E-T, Isopimarane Diterpenes and a 20--Isopimarane, from (IBT 19404): Structures and Inhibitory Effects on RANKL-Induced Formation of Multinuclear Osteoclasts. Journal of Natural Products. PMID 34464116 DOI: 10.1021/acs.jnatprod.1c00486 |
0.38 |
|
| 2021 |
Mintoff SJL, Nguyen TV, Kelly C, Cullen S, Hearnden M, Williams R, Daniells JW, Tran-Nguyen LTT. Banana Cultivar Field Screening for Resistance to f.sp. Tropical Race 4 in the Northern Territory. Journal of Fungi (Basel, Switzerland). 7. PMID 34436166 DOI: 10.3390/jof7080627 |
0.343 |
|
| 2021 |
Tao J, Montgomery MC, Williams R, Patil P, Rogers BG, Sosnowy C, Murphy M, Zanowick-Marr A, Maynard M, Napoleon SC, Chu C, Almonte A, Nunn AS, Chan PA. Loss to Follow-Up and Re-Engagement in HIV Pre-Exposure Prophylaxis Care in the United States, 2013-2019. Aids Patient Care and Stds. 35: 271-277. PMID 34242092 DOI: 10.1089/apc.2021.0074 |
0.334 |
|
| 2020 |
Al Mortadi N, Alzoubi KH, Williams R. A Scoping Review on the Accuracy of Fit of Removable Partial Dentures in a Developing Digital Context. Clinical, Cosmetic and Investigational Dentistry. 12: 551-562. PMID 33244275 DOI: 10.2147/CCIDE.S282300 |
0.325 |
|
| 2020 |
Ye Y, Du L, Zhang X, Newmister SA, McCauley M, Alegre-Requena JV, Zhang W, Mu S, Minami A, Fraley AE, Adrover-Castellano ML, Carney NA, Shende VV, Qi F, Oikawa H, ... ... Williams RM, et al. Fungal-derived brevianamide assembly by a stereoselective semipinacolase. Nature Catalysis. 3: 497-506. PMID 32923978 DOI: 10.1038/s41929-020-0454-9 |
0.403 |
|
| 2020 |
Sadahiro Y, Kato H, Williams RM, Tsukamoto S. Irpexine, an Isoindolinone Alkaloid Produced by Coculture of Endophytic Fungi, and . Journal of Natural Products. PMID 32301614 DOI: 10.1021/Acs.Jnatprod.0C00047 |
0.385 |
|
| 2020 |
Fraley AE, Tran HT, Kelly SP, Newmister SA, Tripathi A, Kato H, Tsukamoto S, Du L, Li S, Williams RM, Sherman DH. Flavin-Dependent Monooxygenases NotI and NotI' Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides. Chembiochem : a European Journal of Chemical Biology. PMID 32246875 DOI: 10.1002/Cbic.202000004 |
0.399 |
|
| 2020 |
Li S, Newmister SA, Lowell AN, Zi J, Chappell CR, Yu F, Hohlman RM, Orjala J, Williams RM, Sherman DH. Control of stereoselectivity in diverse hapalindole metabolites is mediated by cofactor induced combinatorial pairing of Stig cyclases. Angewandte Chemie (International Ed. in English). PMID 32052896 DOI: 10.1002/Anie.201913686 |
0.374 |
|
| 2020 |
Thielman JR, Sherman DH, Williams RM. Stereoselective Synthesis of Baulamycin A. The Journal of Organic Chemistry. PMID 31970985 DOI: 10.1021/Acs.Joc.9B03443 |
0.405 |
|
| 2020 |
Maiorana A, Kegeles SM, Brown S, Williams R, Arnold EA. Substance use, intimate partner violence, history of incarceration and vulnerability to HIV among young Black men who have sex with men in a Southern US city. Culture, Health & Sexuality. 1-15. PMID 31944158 DOI: 10.1080/13691058.2019.1688395 |
0.325 |
|
| 2020 |
Fraley A, Caddell Haatveit K, Ye Y, Kelly SP, Newmister SA, Yu F, Williams RM, Smith JL, Houk KN, Sherman DH. Molecular basis for spirocycle formation in the paraherquamide biosynthetic pathway. Journal of the American Chemical Society. PMID 31904957 DOI: 10.2210/Pdb6Pvi/Pdb |
0.388 |
|
| 2019 |
Brierley RC, Gaunt D, Metcalfe C, Blazeby JM, Blencowe NS, Jepson M, Berrisford RG, Avery KNL, Hollingworth W, Rice CT, Moure-Fernandez A, Wong N, Nicklin J, Skilton A, Boddy A, ... ... Williams R, et al. Laparoscopically assisted versus open oesophagectomy for patients with oesophageal cancer-the Randomised Oesophagectomy: Minimally Invasive or Open (ROMIO) study: protocol for a randomised controlled trial (RCT). Bmj Open. 9: e030907. PMID 31748296 DOI: 10.1136/bmjopen-2019-030907 |
0.333 |
|
| 2019 |
Dan Q, Newmister SA, Klas KR, Fraley AE, McAfoos TJ, Somoza AD, Sunderhaus JD, Ye Y, Shende VV, Yu F, Sanders JN, Brown WC, Zhao L, Paton RS, Houk KN, ... ... Williams RM, et al. Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase. Nature Chemistry. PMID 31548667 DOI: 10.1038/S41557-019-0326-6 |
0.405 |
|
| 2019 |
de Almeida L, Williams R, Soares DM, Nesbitt H, Wright G, Erskine W. Aflatoxin levels in maize and peanut and blood in women and children: The case of Timor-Leste. Scientific Reports. 9: 13158. PMID 31511633 DOI: 10.1038/s41598-019-49584-1 |
0.323 |
|
| 2019 |
Mayer J, Williams R, Kleine S, He B, Meichner T, Gogal RM. Immunomodulatory effects of dietary IMUNO-2865 in mice, pre-and post-vaccine challenge with parainfluenza virus 5. International Immunopharmacology. 76: 105846. PMID 31470267 DOI: 10.1016/j.intimp.2019.105846 |
0.318 |
|
| 2019 |
Beyett TS, Fraley AE, Labudde E, Patra D, Coleman RC, Eguchi A, Glukhova A, Chen Q, Williams RM, Koch WJ, Sherman DH, Tesmer JJG. Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe. Proceedings of the National Academy of Sciences of the United States of America. PMID 31337679 DOI: 10.1073/Pnas.1818547116 |
0.348 |
|
| 2019 |
Williams R, Jupiter DC, Maassen NH. The Incidence and Risk Factors of Scaphoid Fracture Associated With Radial Head and Neck Fracture in Trauma Patients. Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews. 3: e055. PMID 31321373 DOI: 10.5435/JAAOSGlobal-D-19-00055 |
0.321 |
|
| 2019 |
Chaabane M, Williams RM, Stephens AT, Park JW. circDeep: Deep learning approach for circular RNA classification from other long non-coding RNA. Bioinformatics (Oxford, England). PMID 31268128 DOI: 10.1093/Bioinformatics/Btz537 |
0.307 |
|
| 2019 |
Kato H, Sebe M, Nagaki M, Eguchi K, Kagiyama I, Hitora Y, Frisvad JC, Williams RM, Tsukamoto S. Taichunins A-D, Norditerpenes from Aspergillus taichungensis (IBT 19404). Journal of Natural Products. PMID 30995043 DOI: 10.1021/acs.jnatprod.8b01032 |
0.352 |
|
| 2018 |
Kai A, Kato H, Sherman DH, Williams RM, Tsukamoto S. Isolation of a new indoxyl alkaloid, Amoenamide B, from NRRL 35600: biosynthetic implications and correction of the structure of Speramide B. Tetrahedron Letters. 50: 4236-4240. PMID 30765898 DOI: 10.1016/J.Tetlet.2018.10.034 |
0.371 |
|
| 2018 |
Button B, Goodell HP, Atieh E, Chen YC, Williams R, Shenoy S, Lackey E, Shenkute NT, Cai LH, Dennis RG, Boucher RC, Rubinstein M. Roles of mucus adhesion and cohesion in cough clearance. Proceedings of the National Academy of Sciences of the United States of America. PMID 30420506 DOI: 10.1073/Pnas.1811787115 |
0.326 |
|
| 2018 |
Elias A, Cummins T, Tyrrell R, Lamb F, Dore V, Williams R, Rosenfeld J, Hopwood M, Villemagne VL, Rowe CC. Risk of Alzheimer's Disease in Obstructive Sleep Apnea Syndrome: Amyloid-β and Tau Imaging. Journal of Alzheimer's Disease : Jad. PMID 30320587 DOI: 10.3233/JAD-180640 |
0.305 |
|
| 2018 |
Newmister SA, Romminger S, Schmidt JJ, Williams RM, Smith JL, Berlinck RGS, Sherman DH. Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. Organic & Biomolecular Chemistry. PMID 30141817 DOI: 10.1039/C8Ob01565A |
0.378 |
|
| 2018 |
Sanders J, Williams R. The Relationship Between Video Gaming, Gambling, and Problematic Levels of Video Gaming and Gambling. Journal of Gambling Studies. PMID 30121839 DOI: 10.1007/s10899-018-9798-3 |
0.304 |
|
| 2018 |
Kato H, Kai A, Kawabata T, Sunderhaus JD, McAfoos TJ, Finefield JM, Sugimoto Y, Williams RM, Tsukamoto S. Corrigendum to "Enantioselective inhibitory abilities of enantiomers of notoamides against RANKL-induced formation of multinuclear osteoclasts" [Bioorg. Med. Chem. Lett. 27 (22) (2017) 4975-4978]. Bioorganic & Medicinal Chemistry Letters. PMID 29903661 DOI: 10.1016/J.Bmcl.2018.06.013 |
0.351 |
|
| 2018 |
Klas KR, Kato H, Frisvad JC, Yu F, Newmister SA, Fraley AE, Sherman DH, Tsukamoto S, Williams RM. Structural and stereochemical diversity in prenylated indole alkaloids containing the bicyclo[2.2.2]diazaoctane ring system from marine and terrestrial fungi. Natural Product Reports. PMID 29632911 DOI: 10.1039/C7Np00042A |
0.396 |
|
| 2018 |
Newmister SA, Li S, Garcia-Borràs M, Sanders JN, Yang S, Lowell AN, Yu F, Smith JL, Williams RM, Houk KN, Sherman DH. Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis. Nature Chemical Biology. PMID 29531360 DOI: 10.1038/S41589-018-0003-X |
0.392 |
|
| 2017 |
Zhao L, Dunne CE, Clausen DJ, Roberts JM, Paulk J, Liu H, Wiest OG, Bradner JE, Williams RM. Synthesis and Biochemical Evaluation of Biotinylated Conjugates of Largazole Analogues: Selective Class I Histone Deacetylase Inhibitors. Israel Journal of Chemistry. 57: 319-330. PMID 30760938 DOI: 10.1002/Ijch.201600130 |
0.374 |
|
| 2017 |
Sugimoto K, Sadahiro Y, Kagiyama I, Kato H, Sherman DH, Williams RM, Tsukamoto S. Isolation of amoenamide A and five antipodal prenylated alkaloids fromNRRL 35600. Tetrahedron Letters. 58: 2797-2800. PMID 29622844 DOI: 10.1016/J.Tetlet.2017.05.057 |
0.374 |
|
| 2017 |
Kato H, Nakahara T, Sugimoto K, Matsuo K, Kagiyama I, Frisvad JC, Sherman DH, Williams RM, Tsukamoto S. Correction to "Isolation of Notoamide S and Enantiomeric 6-epi-Stephacidin A from the Terrestrial Fungus Aspergillus amoenus: Biogenetic Implications". Organic Letters. PMID 29235872 DOI: 10.1021/Acs.Orglett.7B03781 |
0.344 |
|
| 2017 |
Kato H, Kai A, Kawabata T, Sunderhaus JD, McAfoos TJ, Finefield JM, Sugimoto Y, Williams RM, Tsukamoto S. Enantioselective inhibitory abilities of enantiomers of notoamides against RANKL-induced formation of multinuclear osteoclasts. Bioorganic & Medicinal Chemistry Letters. PMID 29037945 DOI: 10.1016/J.Bmcl.2017.10.017 |
0.374 |
|
| 2017 |
Bueno JAH, Arias L, Yu CR, Williams R, Komm BS. Efficacy and safety of bazedoxifene in postmenopausal Latino women with osteoporosis. Menopause (New York, N.Y.). 24: 1033-1039. PMID 28837504 DOI: 10.1097/Gme.0000000000000889 |
0.336 |
|
| 2017 |
Albert BJ, Niu A, Ramani R, Marshall GR, Wender PA, Williams RM, Ratner L, Barnes AB, Kyei GB. Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation. Scientific Reports. 7: 7456. PMID 28785069 DOI: 10.1038/S41598-017-07814-4 |
0.349 |
|
| 2017 |
Fraley AE, Garcia-Borràs M, Tripathi A, Khare D, Mercado-Marin EV, Tran H, Dan Q, Webb G, Watts K, Crews P, Sarpong R, Williams RM, Smith JL, Houk KN, Sherman DH. Function and structure of MalA/MalA', iterative halogenases for late-stage C-H functionalization of indole alkaloids. Journal of the American Chemical Society. PMID 28777910 DOI: 10.1021/Jacs.7B06773 |
0.401 |
|
| 2017 |
Bacon K, Boyer R, Denbow C, O'Keefe S, Neilson A, Williams R. Antibacterial activity of jalapeño pepper (Capsicum annuum var. annuum) extract fractions against select foodborne pathogens. Food Science & Nutrition. 5: 730-738. PMID 28572963 DOI: 10.1002/fsn3.453 |
0.368 |
|
| 2017 |
Bacon K, Boyer R, Denbow C, O'Keefe S, Neilson A, Williams R. Evaluation of different solvents to extract antibacterial compounds from jalapeño peppers. Food Science & Nutrition. 5: 497-503. PMID 28572934 DOI: 10.1002/fsn3.423 |
0.339 |
|
| 2017 |
Newman R, Ahlfors H, Saveliev A, Galloway A, Hodson DJ, Williams R, Besra GS, Cook CN, Cunningham AF, Bell SE, Turner M. Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1. Nature Immunology. PMID 28394372 DOI: 10.1038/Ni.3724 |
0.335 |
|
| 2017 |
Li S, Lowell AN, Newmister SA, Yu F, Williams RM, Sherman DH. Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids. Nature Chemical Biology. PMID 28288107 DOI: 10.1038/Nchembio.2327 |
0.38 |
|
| 2017 |
Cheruiyot C, Pataki Z, Williams R, Ramratnam B, Li M. SILAC Based Proteomic Characterization of Exosomes from HIV-1 Infected Cells. Journal of Visualized Experiments : Jove. PMID 28287540 DOI: 10.3791/54799 |
0.34 |
|
| 2017 |
Payne C, Batouli A, Stabingas K, Alcindor D, Abdel Aziz K, Pu C, Tyler-Kabara E, Williams R, Yu A. A Pediatric Tumor Found Frequently in the Adult Population: A Case of Anaplastic Astroblastoma in an Elderly Patient and Review of the Literature. Case Reports in Neurological Medicine. 2017: 1607915. PMID 28239500 DOI: 10.1155/2017/1607915 |
0.309 |
|
| 2016 |
Loignon C, Gottin T, Valois C, Couturier F, Williams R, Roy PM. Reflective practice and social responsibility in family medicine: Effect of performing an international rotation in a developing country. Canadian Family Physician Medecin De Famille Canadien. 62: e699-e704. PMID 28661890 |
0.321 |
|
| 2016 |
Loignon C, Gottin T, Valois C, Couturier F, Williams R, Roy PM. Canadian Family Physician Medecin De Famille Canadien. 62: 912-918. PMID 28661873 |
0.372 |
|
| 2016 |
Williams R, Snowden C, Frank RD, Thiel DD. Has Sliding-Clip Renorrhaphy Eliminated the Need for Collecting System Repair During Robot-Assisted Partial Nephrectomy? Journal of Endourology. PMID 27960537 DOI: 10.1089/end.2016.0562 |
0.305 |
|
| 2016 |
Comfort P, Williams R, Suchomel TJ, Lake JP. A comparison of catch phase force-time characteristics during clean derivatives from the knee. Journal of Strength and Conditioning Research. PMID 27749730 DOI: 10.1519/JSC.0000000000001660 |
0.313 |
|
| 2016 |
Newmister SA, Gober CM, Romminger S, Yu F, Tripathi A, Parra LL, Williams RM, Berlinck RG, Joullié MM, Sherman DH. OxaD, a versatile indolic nitrone synthase from the marine-derived fungus Penicillium oxalicum F30. Journal of the American Chemical Society. PMID 27505044 DOI: 10.1021/Jacs.6B04915 |
0.392 |
|
| 2016 |
Palacios S, Williams R, Mirkin S, Pan K, Arias L, Komm BS. Efficacy and tolerability of bazedoxifene in Mexican women with osteoporosis: a subgroup analysis of a randomized phase 3 trial. Menopause (New York, N.Y.). PMID 27116464 DOI: 10.1097/GME.0000000000000610 |
0.337 |
|
| 2016 |
Atcheson CL, Spivack J, Williams R, Bryson EO. Preventable drug waste among anesthesia providers: opportunities for efficiency. Journal of Clinical Anesthesia. 30: 24-32. PMID 27041259 DOI: 10.1016/J.Jclinane.2015.12.005 |
0.336 |
|
| 2016 |
Yokoya M, Toyoshima R, Suzuki T, Le VH, Williams RM, Saito N. Stereoselective Total Synthesis of (-)-Renieramycin T. The Journal of Organic Chemistry. PMID 27019081 DOI: 10.1021/Acs.Joc.6B00327 |
0.362 |
|
| 2016 |
Williams R, Pernetta AP, Horrocks JA. Outcompeted by an invader? Interference and exploitative competition between tropical house gecko (Hemidactylus mabouia) and Barbados leaf-toed gecko (Phyllodactylus pulcher) for diurnal refuges in anthropogenic coastal habitats. Integrative Zoology. 11: 229-38. PMID 26923791 DOI: 10.1111/1749-4877.12194 |
0.334 |
|
| 2015 |
Kagiyama I, Kato H, Nehira T, Frisvad JC, Sherman DH, Williams RM, Tsukamoto S. Taichunamides: Prenylated Indole Alkaloids from Aspergillus taichungensis (IBT 19404). Angewandte Chemie (International Ed. in English). PMID 26644336 DOI: 10.1002/Anie.201509462 |
0.39 |
|
| 2015 |
Li S, Lowell AN, Yu F, Raveh A, Newmister SA, Bair N, Schaub JM, Williams RM, Sherman DH. Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C-C Bond-Forming Cascade. Journal of the American Chemical Society. PMID 26629885 DOI: 10.1021/Jacs.5B10136 |
0.371 |
|
| 2015 |
Campbell-Voytal K, Daly JM, Nagykaldi ZJ, Aspy CB, Dolor RJ, Fagnan LJ, Levy BT, Palac HL, Michaels L, Patterson VB, Kano M, Smith PD, Sussman AL, Williams R, Sterling P, et al. Team Science Approach to Developing Consensus on Research Good Practices for Practice-Based Research Networks: A Case Study. Clinical and Translational Science. PMID 26602516 DOI: 10.1111/Cts.12363 |
0.334 |
|
| 2015 |
Klas K, Tsukamoto S, Sherman DH, Williams RM. Natural Diels-Alderases: Elusive and Irresistable. The Journal of Organic Chemistry. PMID 26495876 DOI: 10.1021/Acs.Joc.5B01951 |
0.35 |
|
| 2015 |
Carreras-Sospedra M, Williams R, Dabdub D. Assessment of the Emissions and Air quality Impacts of Biomass and Biogas Use in California. Journal of the Air & Waste Management Association (1995). PMID 26378722 DOI: 10.1080/10962247.2015.1087892 |
0.321 |
|
| 2015 |
Dolor RJ, Campbell-Voytal K, Daly J, Nagykaldi ZJ, O'Beirne M, Sterling P, Fagnan LJ, Levy B, Michaels L, Louks HA, Smith P, Aspy CB, Patterson VB, Kano M, Sussman AL, ... Williams R, et al. Practice-based Research Network Research Good Practices (PRGPs): Summary of Recommendations. Clinical and Translational Science. PMID 26296309 DOI: 10.1111/Cts.12317 |
0.311 |
|
| 2015 |
Shi J, Habben JE, Archilbald RL, Drummond B, Chamberlin MA, Williams R, Lafitte R, Weers B. Over-expression of ARGOS genes modifies plant sensitivity to ethylene, leading to improved drought tolerance in both Arabidopsis and maize. Plant Physiology. PMID 26220950 DOI: 10.1104/pp.15.00780 |
0.332 |
|
| 2015 |
Sherman DH, Tsukamoto S, Williams RM. ORGANIC SYNTHESIS. Comment on "Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence". Science (New York, N.Y.). 349: 149. PMID 26160938 DOI: 10.1126/Science.Aaa9349 |
0.361 |
|
| 2015 |
McDonald FB, Williams R, Sheehan D, O'Halloran KD. Early life exposure to chronic intermittent hypoxia causes upper airway dilator muscle weakness, which persists into young adulthood. Experimental Physiology. PMID 26096367 DOI: 10.1113/Ep085003 |
0.321 |
|
| 2015 |
Clausen DJ, Smith WB, Haines BE, Wiest O, Bradner JE, Williams RM. Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole. Bioorganic & Medicinal Chemistry. 23: 5061-74. PMID 26054247 DOI: 10.1016/J.Bmc.2015.03.063 |
0.386 |
|
| 2015 |
Ellis AJ, Hendrick VM, Williams R, Komm BS. Selective estrogen receptor modulators in clinical practice: a safety overview. Expert Opinion On Drug Safety. 14: 921-34. PMID 25936229 DOI: 10.1517/14740338.2015.1014799 |
0.336 |
|
| 2015 |
Beck TJ, Fuerst T, Gaither KW, Sutradhar S, Levine AB, Hines T, Yu CR, Williams R, Mirkin S, Chines AA. The effects of bazedoxifene on bone structural strength evaluated by hip structure analysis. Bone. 77: 115-9. PMID 25917574 DOI: 10.1016/j.bone.2015.04.027 |
0.352 |
|
| 2015 |
Decroos C, Clausen DJ, Haines BE, Wiest O, Williams RM, Christianson DW. Variable active site loop conformations accommodate the binding of macrocyclic largazole analogues to HDAC8. Biochemistry. 54: 2126-35. PMID 25793284 DOI: 10.1021/Acs.Biochem.5B00010 |
0.373 |
|
| 2015 |
Kato H, Nakahara T, Yamaguchi M, Kagiyama I, Finefield JM, Sunderhaus JD, Sherman DH, Williams RM, Tsukamoto S. Bioconversion of 6-epi-Notoamide T Produces Metabolites of Unprecedented Structures in a Marine-derived Aspergillus sp. Tetrahedron Letters. 56: 247-251. PMID 25767298 DOI: 10.1016/J.Tetlet.2014.11.083 |
0.371 |
|
| 2015 |
Williams R, Lemaire P, Lewis P, McDonald FB, Lucking E, Hogan S, Sheehan D, Healy V, O'Halloran KD. Chronic intermittent hypoxia increases rat sternohyoid muscle NADPH oxidase expression with attendant modest oxidative stress. Frontiers in Physiology. 6: 15. PMID 25688214 DOI: 10.3389/Fphys.2015.00015 |
0.334 |
|
| 2015 |
Palacios S, Silverman SL, de Villiers TJ, Levine AB, Goemaere S, Brown JP, De Cicco Nardone F, Williams R, Hines TL, Mirkin S, Chines AA. A 7-year randomized, placebo-controlled trial assessing the long-term efficacy and safety of bazedoxifene in postmenopausal women with osteoporosis: effects on bone density and fracture. Menopause (New York, N.Y.). PMID 25668306 DOI: 10.1097/GME.0000000000000419 |
0.346 |
|
| 2015 |
Pilon JL, Clausen DJ, Hansen RJ, Lunghofer PJ, Charles B, Rose BJ, Thamm DH, Gustafson DL, Bradner JE, Williams RM. Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere. Cancer Chemotherapy and Pharmacology. 75: 671-82. PMID 25616967 DOI: 10.1007/S00280-015-2675-1 |
0.386 |
|
| 2015 |
Kato H, Nakahara T, Sugimoto K, Matsuo K, Kagiyama I, Frisvad JC, Sherman DH, Williams RM, Tsukamoto S. Isolation of notoamide S and enantiomeric 6-epi-stephacidin A from the fungus Aspergillus amoenus: biogenetic implications. Organic Letters. 17: 700-3. PMID 25615822 DOI: 10.1021/Ol5037198 |
0.357 |
|
| 2014 |
Krist AH, Aycock RA, Etz RS, Devoe JE, Sabo RT, Williams R, Stein KL, Iwamoto G, Puro J, Deshazo J, Kashiri PL, Arkind J, Romney C, Kano M, Nelson C, et al. MyPreventiveCare: implementation and dissemination of an interactive preventive health record in three practice-based research networks serving disadvantaged patients--a randomized cluster trial. Implementation Science : Is. 9: 181. PMID 25500097 DOI: 10.1186/S13012-014-0181-1 |
0.331 |
|
| 2014 |
Beyene D, Daremipouran M, Apprey V, Williams R, Ricks-Santi L, Kassim OO, Naab TJ, Kanaan YM, Copeland RL. Use of tanning potential as a predictor for prostate cancer risk in African-American men. In Vivo (Athens, Greece). 28: 1181-7. PMID 25398820 |
0.321 |
|
| 2014 |
Williams R. Discontinued in 2013: oncology drugs. Expert Opinion On Investigational Drugs. 24: 95-110. PMID 25315907 DOI: 10.1517/13543784.2015.971154 |
0.353 |
|
| 2014 |
Pearson AD, Williams RM. Synthetic studies towards Zetekitoxin AB: preparation of 4,5-epi-11-hydroxy-saxitoxinol. Tetrahedron. 70: 7942-7949. PMID 25313264 DOI: 10.1016/J.Tet.2014.08.058 |
0.363 |
|
| 2014 |
Dheensa S, Metcalfe PA, Williams R. What do men want from antenatal screening? Findings from an interview study in England. Midwifery. 31: 208-14. PMID 25242107 DOI: 10.1016/j.midw.2014.08.011 |
0.328 |
|
| 2014 |
Williams R, Pfister R, Black I. The neonatologist's role in pediatric anesthesia neurotoxicity. Jama Pediatrics. 168: 701-3. PMID 24934400 DOI: 10.1001/jamapediatrics.2014.469 |
0.315 |
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| 2014 |
Satcher RL, Bogler O, Hyle L, Lee A, Simmons A, Williams R, Hawk E, Matin S, Brewster AM. Telemedicine and telesurgery in cancer care: inaugural conference at MD Anderson Cancer Center. Journal of Surgical Oncology. 110: 353-9. PMID 24889208 DOI: 10.1002/Jso.23652 |
0.314 |
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| 2014 |
O'Byrne PM, Williams R, Walsh JJ, Gilmer JF. Part Two: Evaluation of N-methylbupropion as a Potential Bupropion Prodrug. Pharmaceuticals (Basel, Switzerland). 7: 676-94. PMID 24878537 DOI: 10.3390/ph7060676 |
0.318 |
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| 2014 |
O'Byrne PM, Williams R, Walsh JJ, Gilmer JF. Synthesis, screening and pharmacokinetic evaluation of potential prodrugs of bupropion. Part one: in vitro development. Pharmaceuticals (Basel, Switzerland). 7: 595-620. PMID 24830986 DOI: 10.3390/ph7050595 |
0.353 |
|
| 2014 |
Welch TR, Williams RM. Epidithiodioxopiperazines. occurrence, synthesis and biogenesis. Natural Product Reports. 31: 1376-404. PMID 24816491 DOI: 10.1039/C3Np70097F |
0.4 |
|
| 2014 |
Concha-Meyer A, Eifert J, Williams R, Marcy J, Welbaum G. Survival of Listeria monocytogenes on fresh blueberries (Vaccinium corymbosum) stored under controlled atmosphere and ozone. Journal of Food Protection. 77: 832-6. PMID 24780341 DOI: 10.4315/0362-028X.Jfp-13-441 |
0.332 |
|
| 2014 |
Ellis AG, Reginster JY, Luo X, Bushmakin AG, Williams R, Sutradhar S, Mirkin S, Jansen JP. Indirect comparison of bazedoxifene vs oral bisphosphonates for the prevention of vertebral fractures in postmenopausal osteoporotic women. Current Medical Research and Opinion. 30: 1617-26. PMID 24773456 DOI: 10.1185/03007995.2014.908279 |
0.338 |
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| 2014 |
Pan G, Williams RM. Efficient Synthesis of the Cyclopentanone Fragrances (Z)-3-(2-oxopropyl)-2-(pent-2-en-1-yl)cyclopentanone and Magnolione. Tetrahedron. 70: 276-279. PMID 24729640 DOI: 10.1016/J.Tet.2013.11.066 |
0.332 |
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| 2014 |
Chen Z, Forman LW, Williams RM, Faller DV. Protein kinase C-δ inactivation inhibits the proliferation and survival of cancer stem cells in culture and in vivo. Bmc Cancer. 14: 90. PMID 24528676 DOI: 10.1186/1471-2407-14-90 |
0.356 |
|
| 2014 |
Takashima A, English B, Chen Z, Cao J, Cui R, Williams RM, Faller DV. Protein kinase Cδ is a therapeutic target in malignant melanoma with NRAS mutation. Acs Chemical Biology. 9: 1003-14. PMID 24506253 DOI: 10.1021/Cb400837T |
0.356 |
|
| 2014 |
Shortt CM, Fredsted A, Chow HB, Williams R, Skelly JR, Edge D, Bradford A, O'Halloran KD. Reactive oxygen species mediated diaphragm fatigue in a rat model of chronic intermittent hypoxia. Experimental Physiology. 99: 688-700. PMID 24443349 DOI: 10.1113/Expphysiol.2013.076828 |
0.337 |
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| 2014 |
Thompson MG, Black CC, Pavlicek RL, Honnold CL, Wise MC, Alamneh YA, Moon JK, Kessler JL, Si Y, Williams R, Yildirim S, Kirkup BC, Green RK, Hall ER, Palys TJ, et al. Validation of a novel murine wound model of Acinetobacter baumannii infection. Antimicrobial Agents and Chemotherapy. 58: 1332-42. PMID 24342634 DOI: 10.1128/Aac.01944-13 |
0.338 |
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| 2013 |
Jiménez-Somarribas A, Williams RM. Synthetic studies on lemonomycin: construction of the tetracyclic core. Tetrahedron. 69: 7505-7512. PMID 25083002 DOI: 10.1016/J.Tet.2013.05.009 |
0.368 |
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| 2013 |
Welch TR, Williams RM. Studies on the Biosynthesis of Chetomin: Enantiospecific Synthesis of a Putative, Late-Stage Biosynthetic Intermediate. Tetrahedron. 69: 770-773. PMID 24489414 DOI: 10.1016/J.Tet.2012.10.075 |
0.375 |
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| 2013 |
Williams RM. What are the true costs of emergency department services? Annals of Emergency Medicine. 62: 552-3. PMID 24161119 DOI: 10.1016/j.annemergmed.2013.05.016 |
0.3 |
|
| 2013 |
Williams R. Discontinued drugs in 2012: oncology drugs. Expert Opinion On Investigational Drugs. 22: 1627-44. PMID 24102323 DOI: 10.1517/13543784.2013.847088 |
0.333 |
|
| 2013 |
McClure MC, Sonstegard TS, Wiggans GR, Van Eenennaam AL, Weber KL, Penedo CT, Berry DP, Flynn J, Garcia JF, Carmo AS, Regitano LC, Albuquerque M, Silva MV, Machado MA, Coffey M, ... ... Williams R, et al. Imputation of microsatellite alleles from dense SNP genotypes for parentage verification across multiple Bos taurus and Bos indicus breeds. Frontiers in Genetics. 4: 176. PMID 24065982 DOI: 10.3389/Fgene.2013.00176 |
0.306 |
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| 2013 |
Guerra-Bubb JM, Bowers AA, Smith WB, Paranal R, Estiu G, Wiest O, Bradner JE, Williams RM. Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs. Bioorganic & Medicinal Chemistry Letters. 23: 6025-8. PMID 24035339 DOI: 10.1016/J.Bmcl.2013.06.012 |
0.373 |
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| 2013 |
Palacios S, de Villiers TJ, Nardone Fde C, Levine AB, Williams R, Hines T, Mirkin S, Chines AA. Assessment of the safety of long-term bazedoxifene treatment on the reproductive tract in postmenopausal women with osteoporosis: results of a 7-year, randomized, placebo-controlled, phase 3 study. Maturitas. 76: 81-7. PMID 23871271 DOI: 10.1016/j.maturitas.2013.06.008 |
0.337 |
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| 2013 |
Bass PD, Gubler DA, Judd TC, Williams RM. Mitomycinoid alkaloids: mechanism of action, biosynthesis, total syntheses, and synthetic approaches. Chemical Reviews. 113: 6816-63. PMID 23654296 DOI: 10.1021/Cr3001059 |
0.377 |
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| 2013 |
Batchelder AJ, Williams R, Sutton C, Khanna A. The evolution of minimally invasive bariatric surgery. The Journal of Surgical Research. 183: 559-66. PMID 23522984 DOI: 10.1016/j.jss.2013.02.036 |
0.318 |
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| 2013 |
Aviles B, Klotz C, Eifert J, Williams R, Ponder M. Biofilms promote survival and virulence of Salmonella enterica sv. Tennessee during prolonged dry storage and after passage through an in vitro digestion system International Journal of Food Microbiology. 162: 252-259. PMID 23454816 DOI: 10.1016/J.Ijfoodmicro.2013.01.026 |
0.34 |
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| 2013 |
Aviles B, Klotz C, Smith T, Williams R, Ponder M. Survival of salmonella enterica serotype tennessee during simulated gastric passage is improved by low water activity and high fat content Journal of Food Protection. 76: 333-337. PMID 23433384 DOI: 10.4315/0362-028X.Jfp-12-280 |
0.322 |
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| 2013 |
Sunderhaus JD, McAfoos TJ, Finefield JM, Kato H, Li S, Tsukamoto S, Sherman DH, Williams RM. Synthesis and bioconversions of notoamide T: a biosynthetic precursor to stephacidin A and notoamide B. Organic Letters. 15: 22-5. PMID 23249380 DOI: 10.1021/Ol302901P |
0.368 |
|
| 2012 |
Rafferty RJ, Williams RM. FORMAL SYNTHESIS OF HAPALINDOLE O AND SYNTHETIC EFFORTS TOWARDS HAPALINDOLE K AND AMBIGUINE A. Heterocycles. 86: 219-231. PMID 24808627 DOI: 10.3987/Com-12-S(N)3 |
0.404 |
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| 2012 |
Schuber PT, Williams RM. SYNTHETIC STUDIES ON MPC1001: A DIPOLAR CYCLOADDITION APPROACH TO THE PYRROLIDINE RING SYSTEM. Heterocycles. 84: 1193-1207. PMID 23667292 DOI: 10.3987/Com-11-S(P)101 |
0.393 |
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| 2012 |
Li S, Anand K, Tran H, Yu F, Finefield JM, Sunderhaus JD, McAfoos TJ, Tsukamoto S, Williams RM, Sherman DH. Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(-)-notoamide, paraherquamide and malbrancheamide pathways. Medchemcomm. 3: 987-996. PMID 23213353 DOI: 10.1039/C2Md20029E |
0.397 |
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| 2012 |
Williams R. Discontinued drugs in 2011: oncology drugs. Expert Opinion On Investigational Drugs. 22: 9-34. PMID 23127145 DOI: 10.1517/13543784.2013.739605 |
0.343 |
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| 2012 |
Walldén K, Williams R, Yan J, Lian PW, Wang L, Thalassinos K, Orlova EV, Waksman G. Structure of the VirB4 ATPase, alone and bound to the core complex of a type IV secretion system. Proceedings of the National Academy of Sciences of the United States of America. 109: 11348-53. PMID 22745169 DOI: 10.1073/Pnas.1201428109 |
0.344 |
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| 2012 |
Wu S, Jiang Z, Kempinski C, Eric Nybo S, Husodo S, Williams R, Chappell J. Engineering triterpene metabolism in tobacco. Planta. 236: 867-77. PMID 22729821 DOI: 10.1007/S00425-012-1680-4 |
0.363 |
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| 2012 |
Finefield JM, Sherman DH, Kreitman M, Williams RM. Enantiomeric natural products: occurrence and biogenesis. Angewandte Chemie (International Ed. in English). 51: 4802-36. PMID 22555867 DOI: 10.1002/Anie.201107204 |
0.367 |
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| 2012 |
Guerra-Bubb J, Croteau R, Williams RM. The early stages of taxol biosynthesis: an interim report on the synthesis and identification of early pathway metabolites. Natural Product Reports. 29: 683-96. PMID 22547034 DOI: 10.1039/C2Np20021J |
0.396 |
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| 2012 |
Pan G, Williams RM. Unified total syntheses of fawcettimine class alkaloids: fawcettimine, fawcettidine, lycoflexine, and lycoposerramine B. The Journal of Organic Chemistry. 77: 4801-11. PMID 22519642 DOI: 10.1021/Jo3006045 |
0.411 |
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| 2012 |
Williams R, Austin J. Cardiac rehabilitation supports a heterogeneous population of patients. Heart (British Cardiac Society). 98: 673; author reply 67. PMID 22505468 DOI: 10.1136/heartjnl-2012-301769 |
0.304 |
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| 2012 |
Finefield JM, Frisvad JC, Sherman DH, Williams RM. Fungal origins of the bicyclo[2.2.2]diazaoctane ring system of prenylated indole alkaloids. Journal of Natural Products. 75: 812-33. PMID 22502590 DOI: 10.1021/Np200954V |
0.401 |
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| 2012 |
Huff K, Boyer R, Denbow C, O'Keefe S, Williams R. Effect of storage temperature on survival and growth of foodborne pathogens on whole, damaged, and internally inoculated jalapeños (Capsicum annuum var. annuum). Journal of Food Protection. 75: 382-8. PMID 22289602 DOI: 10.4315/0362-028X.JFP-11-304 |
0.307 |
|
| 2012 |
Schuber PT, Williams RM. Synthetic Studies Towards MPC1001: Preparation of a β-hydroxyl-Tyrosine Derivative. Tetrahedron Letters. 53: 380-382. PMID 22287813 DOI: 10.1016/J.Tetlet.2011.11.069 |
0.39 |
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| 2012 |
Williams R, Hewison A, Wagstaff C, Randall D. 'Walk with your head high': African and African-Caribbean fatherhood, children's mental well-being and social capital. Ethnicity & Health. 17: 89-103. PMID 22236078 DOI: 10.1080/13557858.2011.645155 |
0.325 |
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| 2012 |
Li S, Finefield JM, Sunderhaus JD, McAfoos TJ, Williams RM, Sherman DH. Biochemical characterization of NotB as an FAD-dependent oxidase in the biosynthesis of notoamide indole alkaloids. Journal of the American Chemical Society. 134: 788-91. PMID 22188465 DOI: 10.1021/Ja2093212 |
0.416 |
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| 2012 |
Ghosh SK, Perrine SP, Williams RM, Faller DV. Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents. Blood. 119: 1008-17. PMID 22160379 DOI: 10.1182/Blood-2011-06-362434 |
0.359 |
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| 2012 |
Rafferty RJ, Williams RM. Total synthesis of hapalindoles J and U. The Journal of Organic Chemistry. 77: 519-24. PMID 22126131 DOI: 10.1021/Jo202139K |
0.407 |
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| 2012 |
Williams R, Hewison A, Stewart M, Liles C, Wildman S. 'We are doing our best': African and African-Caribbean fatherhood, health and preventive primary care services, in England. Health & Social Care in the Community. 20: 216-23. PMID 22074262 DOI: 10.1111/j.1365-2524.2011.01037.x |
0.34 |
|
| 2011 |
Kato H, Nakamura Y, Finefield JM, Umaoka H, Nakahara T, Williams RM, Tsukamoto S. Study on the biosynthesis of the notoamides: Pinacol-type rearrangement of the isoprenyl unit in deoxybrevianamide E and 6-hydroxydeoxybrevianamide E. Tetrahedron Letters. 52: 6923-6926. PMID 22140281 DOI: 10.1016/J.Tetlet.2011.10.065 |
0.355 |
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| 2011 |
Finefield JM, Greshock TJ, Sherman DH, Tsukamoto S, Williams RM. Notoamide E: Biosynthetic incorporation into notoamides C and D in cultures of Aspergillus versicolor NRRL 35600. Tetrahedron Letters. 52: 1987-1989. PMID 22140279 DOI: 10.1016/J.Tetlet.2011.02.078 |
0.37 |
|
| 2011 |
Vasdev N, Moir J, Dosani MT, Williams R, Soomro N, Talbot D, Rix D. Endourological Management of Urolithiasis in Donor Kidneys prior to Renal Transplant. Isrn Urology. 2011: 242690. PMID 22084792 DOI: 10.5402/2011/242690 |
0.313 |
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| 2011 |
Jannetta PJ, Whiting DM, Fletcher LH, Hobbs JK, Brillman J, Quigley M, Fukui M, Williams R. Parkinson's disease: an inquiry into the etiology and treatment. Neurology International. 3: e7. PMID 22053261 DOI: 10.4081/ni.2011.e7 |
0.319 |
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| 2011 |
Chen Z, Forman LW, Miller KA, English B, Takashima A, Bohacek RA, Williams RM, Faller DV. Protein kinase Cδ inactivation inhibits cellular proliferation and decreases survival in human neuroendocrine tumors. Endocrine-Related Cancer. 18: 759-71. PMID 21990324 DOI: 10.1530/Erc-10-0224 |
0.333 |
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| 2011 |
Williams RM, Stille J, Echavarren A, Hendrix J, Albrecht B, Williams R. Discussion Addendum for: 4-Methoxy-4'-nitrophenyl. Recent Advances in the Stille Biaryl Coupling Reaction and Applications in Complex Natural Products Synthesis. Organic Syntheses; An Annual Publication of Satisfactory Methods For the Preparation of Organic Chemicals. 88: 197-201. PMID 21960729 DOI: 10.1002/0471264229.Os088.18 |
0.38 |
|
| 2011 |
Williams R. Discontinued drugs in 2010: oncology drugs. Expert Opinion On Investigational Drugs. 20: 1479-96. PMID 21955127 DOI: 10.1517/13543784.2011.623697 |
0.34 |
|
| 2011 |
Rath CM, Janto B, Earl J, Ahmed A, Hu FZ, Hiller L, Dahlgren M, Kreft R, Yu F, Wolff JJ, Kweon HK, Christiansen MA, Håkansson K, Williams RM, Ehrlich GD, et al. Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743. Acs Chemical Biology. 6: 1244-56. PMID 21875091 DOI: 10.1021/Cb200244T |
0.397 |
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| 2011 |
Sunderhaus JD, Sherman DH, Williams RM. Studies on the Biosynthesis of the Stephacidin and Notoamide Natural Products: A Stereochemical and Genetic Conundrum. Israel Journal of Chemistry. 51: 442-452. PMID 21818159 DOI: 10.1002/Ijch.201100016 |
0.413 |
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| 2011 |
Finefield JM, Kato H, Greshock TJ, Sherman DH, Tsukamoto S, Williams RM. Biosynthetic studies of the notoamides: isotopic synthesis of stephacidin A and incorporation into notoamide B and sclerotiamide. Organic Letters. 13: 3802-5. PMID 21714564 DOI: 10.1021/Ol201284Y |
0.385 |
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| 2011 |
Rafferty RJ, Williams RM. Synthetic Studies on the Ambiguine Family of Alkaloids: Construction of the ABCD Ring System. Tetrahedron Letters. 52: 2037-2040. PMID 21516192 DOI: 10.1016/J.Tetlet.2010.09.086 |
0.397 |
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| 2011 |
Finefield JM, Sherman DH, Tsukamoto S, Williams RM. Studies on the biosynthesis of the notoamides: synthesis of an isotopomer of 6-hydroxydeoxybrevianamide E and biosynthetic incorporation into notoamide J. The Journal of Organic Chemistry. 76: 5954-8. PMID 21504234 DOI: 10.1021/Jo200218A |
0.403 |
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| 2011 |
Williams RM. Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism. The Journal of Organic Chemistry. 76: 4221-59. PMID 21438619 DOI: 10.1021/Jo2003693 |
0.418 |
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| 2011 |
Bhatia S, Sekula RF, Quigley MR, Williams R, Ku A. Role of calcification in the outcomes of treated, unruptured, intracerebral aneurysms. Acta Neurochirurgica. 153: 905-11. PMID 21286763 DOI: 10.1007/s00701-010-0846-8 |
0.307 |
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| 2010 |
McAfoos TJ, Li S, Tsukamoto S, Sherman DH, Williams RM. STUDIES ON THE BIOSYNTHESIS OF THE STEPHACIDINS AND NOTOAMIDES. TOTAL SYNTHESIS OF NOTOAMIDE S. Heterocycles. 82: 461-472. PMID 21796227 DOI: 10.3987/Com-10-S(E)19 |
0.411 |
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| 2010 |
Namba K, Inai M, Sundermeier U, Greshock TJ, Williams RM. Synthetic Studies on Palau'amine. Construction of the Cyclopentane Core via an Asymmetric 1,3-Dipolar Cycloaddition. Tetrahedron Letters. 51: 6557-6559. PMID 21286237 DOI: 10.1016/J.Tetlet.2010.10.037 |
0.372 |
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| 2010 |
English BJ, Williams RM. A divergent strategy for the synthesis of secologanin derived natural products. The Journal of Organic Chemistry. 75: 7869-76. PMID 20964396 DOI: 10.1021/Jo101775N |
0.336 |
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| 2010 |
Samuel SM, Tonelli MA, Foster BJ, Nettel-Aguirre A, Na Y, Williams R, Soo A, Hemmelgarn BR. Overview of the Canadian pediatric end-stage renal disease database. Bmc Nephrology. 11: 21. PMID 20796306 DOI: 10.1186/1471-2369-11-21 |
0.308 |
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| 2010 |
Taguchi VY, Nieckarz RJ, Clement RE, Krolik S, Williams R. Dioxin analysis by gas chromatography-Fourier transform ion cyclotron resonance mass spectrometry (GC-FTICRMS). Journal of the American Society For Mass Spectrometry. 21: 1918-21. PMID 20727785 DOI: 10.1016/j.jasms.2010.07.010 |
0.318 |
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| 2010 |
Ding Y, de Wet JR, Cavalcoli J, Li S, Greshock TJ, Miller KA, Finefield JM, Sunderhaus JD, McAfoos TJ, Tsukamoto S, Williams RM, Sherman DH. Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus sp. Journal of the American Chemical Society. 132: 12733-40. PMID 20722388 DOI: 10.1021/Ja1049302 |
0.413 |
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| 2010 |
Dalal H, Austin J, Davis R, Jolly K, Green C, Lewin B, Taylor R, Thompson D, Williams R, Wingham J. Congestive heart failure. Don't forget rehabilitation. Bmj (Clinical Research Ed.). 341: c4286. PMID 20699311 |
0.304 |
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| 2010 |
Mickus TJ, Mueller J, Williams R. An uncommon cause of Ortner syndrome. Journal of Thoracic Imaging. 25: W82-4. PMID 20463611 DOI: 10.1097/RTI.0b013e3181bc060d |
0.32 |
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| 2010 |
Finefield JM, Williams RM. Synthesis of notoamide J: a potentially pivotal intermediate in the biosynthesis of several prenylated indole alkaloids. The Journal of Organic Chemistry. 75: 2785-9. PMID 20359229 DOI: 10.1021/Jo100332C |
0.422 |
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| 2010 |
Subramanian V, Williams RM, Boger DL, Luger K. Methods to characterize the effect of DNA-modifying compounds on nucleosomal DNA. Methods in Molecular Biology (Clifton, N.J.). 613: 173-92. PMID 19997884 DOI: 10.1007/978-1-60327-418-0_11 |
0.329 |
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| 2010 |
Williams R. Discontinued drugs in 2008: oncology drugs. Expert Opinion On Investigational Drugs. 18: 1581-94. PMID 19663760 DOI: 10.1517/13543780903151806 |
0.338 |
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| 2009 |
Artman GD, Rafferty RJ, Williams RM, Aaron GL, Davis MM, Brummond KM. (3R,7aS)-3-(TRICHLOROMETHYL)TETRAHYDROPYRROLO[1,2-C]OXAZOL-1(3H)-ONE: AN AIR AND MOISTURE STABLE REAGENT FOR THE SYNTHESIS OF OPTICALLY ACTIVE α-BRANCHED PROLINES. Organic Syntheses; An Annual Publication of Satisfactory Methods For the Preparation of Organic Chemicals. 86: 262. PMID 21331348 |
0.356 |
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| 2009 |
Williams RM, Burnett CM. New Tricks in Amino Acid Synthesis: Applications to Complex Natural Products. Acs Symposium Series. American Chemical Society. 1009: 420-442. PMID 20563264 DOI: 10.1021/bk-2009-1009.ch026 |
0.404 |
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| 2009 |
Miller KA, Tsukamoto S, Williams RM. Asymmetric total syntheses of (+)- and (-)-versicolamide B and biosynthetic implications. Nature Chemistry. 1: 63-8. PMID 20300443 DOI: 10.1038/Nchem.110 |
0.405 |
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| 2009 |
Burnett CM, Williams RM. Asymmetric Synthesis of the Core of AMPTD, the Key Amino Acid of Microsclerodermins F-I. Tetrahedron Letters. 50: 5449-5451. PMID 20191096 DOI: 10.1016/J.Tetlet.2009.06.144 |
0.403 |
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| 2009 |
English BJ, Williams RM. Synthesis of (+/-)-Oleocanthal via a Tandem Intramolecular Michael Cyclization-HWE Olefination. Tetrahedron Letters. 50: 2713. PMID 20161637 DOI: 10.1016/J.Tetlet.2009.03.145 |
0.416 |
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| 2009 |
Sommer K, Williams RM. Studies on Paraherquamide Biosynthesis: Synthesis of Deuterium-Labeled 7-Hydroxy-Pre-Paraherquamide, a Putative Precursor of Paraherquamides A, E & F. Tetrahedron. 65: 3246-3260. PMID 20161298 DOI: 10.1016/J.Tet.2008.08.102 |
0.403 |
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| 2009 |
Gubler DA, Williams RM. Synthetic Studies Towards the Mitomycins: Construction of the Tetracyclic Core via a Reductive Aminocyclization Reaction. Tetrahedron Letters. 50: 4265-4267. PMID 20161278 DOI: 10.1016/J.Tetlet.2009.05.004 |
0.394 |
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| 2009 |
Hodgins DC, Williams R, Munro G. Workplace responsibility, stress, alcohol availability and norms as predictors of alcohol consumption-related problems among employed workers. Substance Use & Misuse. 44: 2062-9. PMID 20001695 DOI: 10.3109/10826080902855173 |
0.308 |
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| 2009 |
Miller KA, Williams RM. Synthetic approaches to the bicyclo[2.2.2]diazaoctane ring system common to the paraherquamides, stephacidins and related prenylated indole alkaloids. Chemical Society Reviews. 38: 3160-74. PMID 19847349 DOI: 10.1039/B816705M |
0.417 |
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| 2009 |
Newkirk TL, Bowers AA, Williams RM. Discovery, biological activity, synthesis and potential therapeutic utility of naturally occurring histone deacetylase inhibitors. Natural Product Reports. 26: 1293-320. PMID 19779641 DOI: 10.1039/B817886K |
0.375 |
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| 2009 |
Gnanasegaran G, Williams R, Mclean E, O' Connell R, Nunan TO, O'Doherty MJ. Lung mass appearing as a dilated left ventricle on Tc-99m tetrofosmin myocardial perfusion scintigraphy. Clinical Nuclear Medicine. 34: 620-1. PMID 19692829 DOI: 10.1097/RLU.0b013e3181b06a6b |
0.309 |
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| 2009 |
Tilman D, Socolow R, Foley JA, Hill J, Larson E, Lynd L, Pacala S, Reilly J, Searchinger T, Somerville C, Williams R. Energy. Beneficial biofuels--the food, energy, and environment trilemma. Science (New York, N.Y.). 325: 270-1. PMID 19608900 DOI: 10.1126/Science.1177970 |
0.311 |
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| 2009 |
Henshall DC, Dürmüller N, White HS, Williams R, Moser P, Dunleavy M, Silverstone PH. Electroencephalographic and behavioral convulsant effects of hydrobromide and hydrochloride salts of bupropion in conscious rodents. Neuropsychiatric Disease and Treatment. 5: 189-206. PMID 19557114 DOI: 10.2147/Ndt.S4714 |
0.324 |
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| 2009 |
Namba K, Kaihara Y, Yamamoto H, Imagawa H, Tanino K, Williams RM, Nishizawa M. Toward Palau'amine: Hg(OTf)2-Catalyzed synthesis of the cyclopentane core Chemistry - a European Journal. 15: 6560-6563. PMID 19492366 DOI: 10.1002/Chem.200900622 |
0.436 |
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| 2009 |
Robertson S, Williams R. Men: showing willing. Community Practitioner : the Journal of the Community Practitioners' & Health Visitors' Association. 82: 34-5. PMID 19397083 |
0.302 |
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| 2009 |
Neustein SM, Williams R. Infection control practices by the anesthesiologist. Anesthesiology. 110: 1191; author reply 1. PMID 19387188 DOI: 10.1097/ALN.0b013e31819facce |
0.303 |
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| 2009 |
Tsukamoto S, Kato H, Greshock TJ, Hirota H, Ohta T, Williams RM. Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp. Journal of the American Chemical Society. 131: 3834-5. PMID 19292484 DOI: 10.1021/Ja810029B |
0.382 |
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| 2009 |
Tsukamoto S, Kawabata T, Kato H, Greshock TJ, Hirota H, Ohta T, Williams RM. Isolation of antipodal (-)-versicolamide B and notoamides L-N from a marine-derived Aspergillus sp. Organic Letters. 11: 1297-300. PMID 19281134 DOI: 10.1021/Ol900071C |
0.372 |
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| 2009 |
Neustein SM, Williams R. An unusual failure of a laryngoscope handle. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. 56: 176-7. PMID 19247769 DOI: 10.1007/s12630-008-9028-z |
0.304 |
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| 2009 |
Bowers AA, West N, Newkirk TL, Troutman-Youngman AE, Schreiber SL, Wiest O, Bradner JE, Williams RM. Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold. Organic Letters. 11: 1301-4. PMID 19239241 DOI: 10.1021/Ol900078K |
0.372 |
|
| 2009 |
Williams R. 'Having a laugh': masculinities, health and humour. Nursing Inquiry. 16: 74-81. PMID 19228306 DOI: 10.1111/j.1440-1800.2009.00437.x |
0.33 |
|
| 2009 |
Bowers AA, Greshock TJ, West N, Estiu G, Schreiber SL, Wiest O, Williams RM, Bradner JE. Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole. Journal of the American Chemical Society. 131: 2900-5. PMID 19193120 DOI: 10.1021/Ja807772W |
0.352 |
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| 2009 |
Chamberland S, Grüschow S, Sherman DH, Williams RM. Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C. Organic Letters. 11: 791-4. PMID 19161340 DOI: 10.1021/Ol802631C |
0.391 |
|
| 2009 |
Ara R, Pandor A, Tumur I, Paisley S, Duenas A, Williams R, Rees A, Wilkinson A, Durrington P, Chilcott J. Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: a Markov model. American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions. 8: 419-27. PMID 19159125 DOI: 10.2165/0129784-200808060-00005 |
0.313 |
|
| 2009 |
Williams R. Discontinued drugs in 2007: oncology drugs. Expert Opinion On Investigational Drugs. 17: 1791-816. PMID 19012497 DOI: 10.1517/13543780802465737 |
0.338 |
|
| 2008 |
Sommer K, Williams RM. Studies Towards Paraherquamides E & F and Related C-labeled Putative Biosynthetic Intermediates: Stereocontrolled Synthesis of the α-Alkyl-β-Methylproline Ring System. Tetrahedron. 64: 7106-7111. PMID 20336192 DOI: 10.1016/J.Tet.2008.05.068 |
0.398 |
|
| 2008 |
Horiguchi T, Rithner CD, Croteau R, Williams RM. Studies on Taxol® Biosynthesis. Preparation and Tritium Labeling of Biosynthetic intermediates by Deoxygenation of a Taxadiene Tetra-acetate Obtained from Japanese Yew. Journal of Labelled Compounds & Radiopharmaceuticals. 51: 325-328. PMID 20221307 DOI: 10.1002/Jlcr.1529 |
0.368 |
|
| 2008 |
Jia X, Williams RM. A Diastereoselective Intramolecular Pauson-Khand Approach to the Construction of the BC Ring System in Tuberostemoninol. Tetrahedron, Asymmetry. 19: 2901-2906. PMID 19779590 DOI: 10.1016/J.Tetasy.2008.11.022 |
0.392 |
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| 2008 |
Li H, Horiguchi T, Croteau R, Williams RM. Studies on Taxol Biosynthesis: Preparation of Taxadiene-diol- and triol-Derivatives by Deoxygenation of Taxusin. Tetrahedron. 64: 6561-6567. PMID 19122848 DOI: 10.1016/J.Tet.2008.04.008 |
0.352 |
|
| 2008 |
Karnon J, Holmes MW, Williams R, Bakhai A, Brennan A. A cost-utility analysis of clopidogrel in patients with ST elevation acute coronary syndromes in the UK. International Journal of Cardiology. 140: 315-22. PMID 19106007 DOI: 10.1016/j.ijcard.2008.11.105 |
0.31 |
|
| 2008 |
Silverstone PH, Williams R, McMahon L, Fleming R, Fogarty S. Effect of increasing intraperitoneal infusion rates on bupropion hydrochloride-induced seizures in mice. Annals of General Psychiatry. 7: 27. PMID 19105845 DOI: 10.1186/1744-859X-7-27 |
0.316 |
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| 2008 |
Miller KA, Figueroa M, Valente MW, Greshock TJ, Mata R, Williams RM. Calmodulin inhibitory activity of the malbrancheamides and various analogs. Bioorganic & Medicinal Chemistry Letters. 18: 6479-81. PMID 18986806 DOI: 10.1016/J.Bmcl.2008.10.057 |
0.381 |
|
| 2008 |
Silverstone PH, Williams R, McMahon L, Fleming R, Fogarty S. Convulsive liability of bupropion hydrochloride metabolites in Swiss albino mice. Annals of General Psychiatry. 7: 19. PMID 18922171 DOI: 10.1186/1744-859X-7-19 |
0.34 |
|
| 2008 |
Ding Y, Greshock TJ, Miller KA, Sherman DH, Williams RM. Premalbrancheamide: synthesis, isotopic labeling, biosynthetic incorporation, and detection in cultures of Malbranchea aurantiaca. Organic Letters. 10: 4863-6. PMID 18844365 DOI: 10.1021/Ol8019633 |
0.373 |
|
| 2008 |
Ara R, Pandor A, Tumur I, Paisley S, Duenas A, Williams R, Wilkinson A, Durrington P, Chilcott J. Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs using data registries. Clinical Therapeutics. 30: 1508-23. PMID 18803993 DOI: 10.1016/j.clinthera.2008.08.002 |
0.322 |
|
| 2008 |
Ding Y, Gruschow S, Greshock TJ, Finefield JM, Sherman DH, Williams RM. Detection of VM55599 and preparaherquamide from Aspergillus japonicus and Penicillium fellutanum: biosynthetic implications. Journal of Natural Products. 71: 1574-8. PMID 18754595 DOI: 10.1021/Np800292N |
0.341 |
|
| 2008 |
Silverstone PH, Williams R, McMahon L, Fleming R, Fogarty S. Alcohol significantly lowers the seizure threshold in mice when co-administered with bupropion hydrochloride. Annals of General Psychiatry. 7: 11. PMID 18706108 DOI: 10.1186/1744-859X-7-11 |
0.311 |
|
| 2008 |
Fishlock D, Williams RM. Synthetic studies on Et-743. Assembly of the pentacyclic core and a formal total synthesis. The Journal of Organic Chemistry. 73: 9594-600. PMID 18687003 DOI: 10.1021/Jo801159K |
0.396 |
|
| 2008 |
Marchan EM, Sekula RF, Ku A, Williams R, O'Neill BR, Wilberger JE, Quigley MR. Hydrogel coil-related delayed hydrocephalus in patients with unruptured aneurysms. Journal of Neurosurgery. 109: 186-90. PMID 18671628 DOI: 10.3171/JNS/2008/109/8/0186 |
0.308 |
|
| 2008 |
Bowers A, West N, Taunton J, Schreiber SL, Bradner JE, Williams RM. Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor. Journal of the American Chemical Society. 130: 11219-22. PMID 18642817 DOI: 10.1021/Ja8033763 |
0.411 |
|
| 2008 |
Ding Y, Williams RM, Sherman DH. Molecular analysis of a 4-dimethylallyltryptophan synthase from Malbranchea aurantiaca. The Journal of Biological Chemistry. 283: 16068-76. PMID 18390548 DOI: 10.1074/Jbc.M801991200 |
0.396 |
|
| 2008 |
Greshock TJ, Grubbs AW, Jiao P, Wicklow DT, Gloer JB, Williams RM. Isolation, structure elucidation, and biomimetic total synthesis of versicolamide B, and the isolation of antipodal (-)-stephacidin A and (+)-notoamide B from Aspergillus versicolor NRRL 35600. Angewandte Chemie (International Ed. in English). 47: 3573-7. PMID 18389509 DOI: 10.1002/Anie.200800106 |
0.416 |
|
| 2008 |
Miller KA, Welch TR, Greshock TJ, Ding Y, Sherman DH, Williams RM. Biomimetic total synthesis of malbrancheamide and malbrancheamide B. The Journal of Organic Chemistry. 73: 3116-9. PMID 18345688 DOI: 10.1021/Jo800116Y |
0.4 |
|
| 2008 |
Williams R. Discontinued drugs in 2006: oncology drugs. Expert Opinion On Investigational Drugs. 17: 269-83. PMID 18321227 DOI: 10.1517/13543784.17.3.269 |
0.339 |
|
| 2008 |
Smith AC, Williams RM. Rabe rest in peace: confirmation of the rabe-kindler conversion of D-quinotoxine into quinine: experimental affirmation of the Woodward-Doering formal total synthesis of quinine. Angewandte Chemie (International Ed. in English). 47: 1736-40. PMID 18236503 DOI: 10.1002/Anie.200705421 |
0.37 |
|
| 2008 |
Greshock TJ, Johns DM, Noguchi Y, Williams RM. Improved total synthesis of the potent HDAC inhibitor FK228 (FR-901228). Organic Letters. 10: 613-6. PMID 18205373 DOI: 10.1021/Ol702957Z |
0.403 |
|
| 2007 |
Vincent G, Lane JW, Williams RM. Regioselectivity of Pictet-Spengler Cyclization Reactions to Construct the Pentacyclic Frameworks of the Ecteinascidin-Saframycin Class of Tetrahydroisoquinoline Antitumor Antibiotics. Tetrahedron Letters. 48: 3719-3722. PMID 19578531 DOI: 10.1016/J.Tetlet.2007.03.113 |
0.383 |
|
| 2007 |
Greshock TJ, Grubbs AW, Williams RM. Concise, Biomimetic Total Synthesis of d,l-Marcfortine C. Tetrahedron. 63: 6124-6130. PMID 18596842 DOI: 10.1016/J.Tet.2007.03.016 |
0.418 |
|
| 2007 |
Jones DT, Artman GD, Williams RM. Coupling of activated esters to gramines in the presence of ethyl propiolate under mild conditions. Tetrahedron Letters. 48: 1291-1294. PMID 18438458 DOI: 10.1016/J.Tetlet.2006.12.016 |
0.374 |
|
| 2007 |
Namiki H, Chamberland S, Gubler DA, Williams RM. Synthetic and biosynthetic studies on FR900482 and mitomycin C: an efficient and stereoselective hydroxymethylation of an advanced benzazocane intermediate. Organic Letters. 9: 5341-4. PMID 18047354 DOI: 10.1021/Ol701960V |
0.414 |
|
| 2007 |
Hare S, Fischer W, Williams R, Terradot L, Bayliss R, Haas R, Waksman G. Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase. The Embo Journal. 26: 4926-34. PMID 17972918 DOI: 10.1038/Sj.Emboj.7601904 |
0.358 |
|
| 2007 |
Greshock TJ, Williams RM. Improved biomimetic total synthesis of D,L-stephacidin A. Organic Letters. 9: 4255-8. PMID 17854197 DOI: 10.1021/Ol701845T |
0.354 |
|
| 2007 |
Jeffrey P, Warne P, Williams R. Addressing the innovation gap. Drug News & Perspectives. 20: 265-9. PMID 17637940 |
0.334 |
|
| 2007 |
Williams R, Delaney T, Nelson E, Gratton J, Laurent J, Heath B. Speeds associated with skiing and snowboarding. Wilderness & Environmental Medicine. 18: 102-5. PMID 17590072 DOI: 10.1580/06-WEME-OR-037R1.1 |
0.322 |
|
| 2007 |
Subramanian V, Ducept P, Williams RM, Luger K. Effects of photochemically activated alkylating agents of the FR900482 family on chromatin. Chemistry & Biology. 14: 553-63. PMID 17524986 DOI: 10.1016/J.Chembiol.2007.04.004 |
0.365 |
|
| 2007 |
Artman GD, Grubbs AW, Williams RM. Concise, asymmetric, stereocontrolled total synthesis of stephacidins A, B and notoamide B. Journal of the American Chemical Society. 129: 6336-42. PMID 17455936 DOI: 10.1021/Ja070259I |
0.416 |
|
| 2007 |
Vincent G, Williams RM. Asymmetric total synthesis of (-)-cribrostatin 4 (renieramycin H). Angewandte Chemie (International Ed. in English). 46: 1517-20. PMID 17387658 DOI: 10.1002/Anie.200604126 |
0.363 |
|
| 2007 |
Kato H, Yoshida T, Tokue T, Nojiri Y, Hirota H, Ohta T, Williams RM, Tsukamoto S. Notoamides A-D: prenylated indole alkaloids isolated from a marine-derived fungus, Aspergillus sp. Angewandte Chemie (International Ed. in English). 46: 2254-6. PMID 17304611 DOI: 10.1002/Anie.200604381 |
0.364 |
|
| 2007 |
Greshock TJ, Grubbs AW, Tsukamoto S, Williams RM. A concise, biomimetic total synthesis of stephacidin A and notoamide B. Angewandte Chemie (International Ed. in English). 46: 2262-5. PMID 17304610 DOI: 10.1002/Anie.200604378 |
0.376 |
|
| 2007 |
Grubbs AW, Artman GD, Tsukamoto S, Williams RM. A concise total synthesis of the notoamides C and D. Angewandte Chemie (International Ed. in English). 46: 2257-61. PMID 17304609 DOI: 10.1002/Anie.200604377 |
0.372 |
|
| 2007 |
Molina-Holgado F, Hider RC, Gaeta A, Williams R, Francis P. Metals ions and neurodegeneration. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 20: 639-54. PMID 17294125 DOI: 10.1007/S10534-006-9033-Z |
0.332 |
|
| 2007 |
Binns HJ, Lanier D, Pace WD, Galliher JM, Ganiats TG, Grey M, Ariza AJ, Williams R. Describing primary care encounters: the Primary Care Network Survey and the National Ambulatory Medical Care Survey. Annals of Family Medicine. 5: 39-47. PMID 17261863 DOI: 10.1370/afm.620 |
0.312 |
|
| 2007 |
Ketchum RE, Horiguchi T, Qiu D, Williams RM, Croteau RB. Administering cultured Taxus cells with early precursors reveals bifurcations in the taxoid biosynthetic pathway. Phytochemistry. 68: 335-41. PMID 17157336 DOI: 10.1016/J.Phytochem.2006.10.019 |
0.332 |
|
| 2006 |
Chen S, Williams RM. Syntheses of Highly Functionalized δ,γ-Unsaturated-α-Amino Acids. Tetrahedron. 62: 11572-11579. PMID 18438461 DOI: 10.1016/J.Tet.2006.09.069 |
0.374 |
|
| 2006 |
Williams RM. Ambulance diversion: economic and policy considerations. Annals of Emergency Medicine. 48: 711-2. PMID 17112934 DOI: 10.1016/j.annemergmed.2006.06.009 |
0.301 |
|
| 2006 |
Johns DM, Mori M, Williams RM. Synthetic studies on quinine: quinuclidine construction via a ketone enolate regio- and diastereoselective Pd-mediated allylic alkylation. Organic Letters. 8: 4051-4. PMID 16928071 DOI: 10.1021/Ol061524S |
0.397 |
|
| 2006 |
Fishlock D, Williams RM. Synthetic studies on Et-743. Asymmetric, stereocontrolled construction of the tetrahydroisoquinoline core via radical cyclization on a glyoxalimine. Organic Letters. 8: 3299-301. PMID 16836390 DOI: 10.1021/Ol061192R |
0.4 |
|
| 2006 |
Alikhan MA, Williams R, Udaya K, Shaefer RF, Viswamitra SC, Kohli M. Evaluation of an adrenal mass in a patient with progressive prostate cancer reveals pheochromocytoma. International Journal of Urology : Official Journal of the Japanese Urological Association. 13: 798-800. PMID 16834663 DOI: 10.1111/j.1442-2042.2006.01405.x |
0.313 |
|
| 2006 |
Williams R, Searcey M, Potter B. Cancer treatments for the new millennium. Drug News & Perspectives. 19: 229-32. PMID 16823498 |
0.334 |
|
| 2006 |
Lane JW, Estevez A, Mortara K, Callan O, Spencer JR, Williams RM. Antitumor activity of tetrahydroisoquinoline analogues 3-epi-jorumycin and 3-epi-renieramycin G. Bioorganic & Medicinal Chemistry Letters. 16: 3180-3. PMID 16632360 DOI: 10.1016/J.Bmcl.2006.03.042 |
0.352 |
|
| 2006 |
Harvey DJ, Williams R, Hill K. A flying start to health promotion in remote north Queensland, Australia: the development of Royal Flying Doctor Service field days Rural and Remote Health. 6: 485. PMID 16524344 |
0.337 |
|
| 2005 |
Williams RM. The costs of visits to emergency departments--revisited. Annals of Emergency Medicine. 46: 471-2; author reply . PMID 16271681 DOI: 10.1016/j.annemergmed.2005.05.037 |
0.303 |
|
| 2005 |
Hak DJ, Wiater PJ, Williams RM, Pierson CL. The effectiveness of standard povidone iodine surgical preparation in decontaminating external fixator components. Injury. 36: 1449-52. PMID 16243337 DOI: 10.1016/j.injury.2005.05.006 |
0.324 |
|
| 2005 |
Lane JW, Chen Y, Williams RM. Asymmetric total syntheses of (-)-jorumycin, (-)-renieramycin G, 3-epi-jorumycin, and 3-epi-renieramycin G. Journal of the American Chemical Society. 127: 12684-90. PMID 16144418 DOI: 10.1002/CHIN.200604202 |
0.412 |
|
| 2005 |
Suzuki T, Honda Y, Izawa K, Williams RM. Remarkable diastereomeric rearrangement of an alpha-acyloxy beta-ketosulfide to an alpha-acyloxy thioester: a novel approach to the synthesis of optically active (2S,3S) beta-amino alpha-hydroxy acids. The Journal of Organic Chemistry. 70: 7317-23. PMID 16122253 DOI: 10.1021/Jo0509915 |
0.383 |
|
| 2005 |
Craven ER, Walters TR, Williams R, Chou C, Cheetham JK, Schiffman R. Brimonidine and timolol fixed-combination therapy versus monotherapy: a 3-month randomized trial in patients with glaucoma or ocular hypertension. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 21: 337-48. PMID 16117698 DOI: 10.1089/jop.2005.21.337 |
0.326 |
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| 2005 |
Williams R, Brown K. Chemical genetics and genomics and drug discovery. Highlights from the Society for Medicines Research symposium held Thursday March 10, 2005, in London, United Kingdom. Drug News & Perspectives. 18: 285-8. PMID 16034486 |
0.339 |
|
| 2005 |
Armstrong-Esther C, Hagen B, Sandilands M, Williams R, Smith C. A longitudinal study of home care clients and their informal carers. British Journal of Community Nursing. 10: 284-91. PMID 15944514 DOI: 10.12968/bjcn.2005.10.6.18169 |
0.326 |
|
| 2005 |
Looper RE, Runnegar MT, Williams RM. Synthesis of the putative structure of 7-deoxycylindrospermopsin: C7 oxygenation is not required for the inhibition of protein synthesis. Angewandte Chemie (International Ed. in English). 44: 3879-81. PMID 15900531 DOI: 10.1002/Anie.200500520 |
0.384 |
|
| 2005 |
Williams R. A project in Pennsylvania Health Progress (Saint Louis, Mo.). 86: 35-37. PMID 15807067 |
0.324 |
|
| 2005 |
Austin J, Williams R, Ross L, Moseley L, Hutchison S. Randomised controlled trial of cardiac rehabilitation in elderly patients with heart failure European Journal of Heart Failure. 7: 411-417. PMID 15718182 DOI: 10.1016/j.ejheart.2004.10.004 |
0.315 |
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| 2005 |
Williams R, Hardcastle N. Best evidence topic report. Humeral fractures and non-accidental injury in children. Emergency Medicine Journal : Emj. 22: 124-5. PMID 15662068 DOI: 10.1136/emj.2004.022061 |
0.329 |
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| 2004 |
Williams R, Morris I. Meeting the needs of type 2 diabetes patients Drug News and Perspectives. 17: 539-542. PMID 15605114 |
0.321 |
|
| 2004 |
Ahrendt KA, Williams RM. A concise asymmetric synthesis of the ADE fragment of nakadomarin A. Organic Letters. 6: 4539-41. PMID 15548070 DOI: 10.1021/Ol048126E |
0.366 |
|
| 2004 |
Looper RE, Williams RM. A concise asymmetric synthesis of the marine hepatotoxin 7-epicylindrospermopsin. Angewandte Chemie (International Ed. in English). 43: 2930-3. PMID 15170307 DOI: 10.1002/Anie.200454208 |
0.407 |
|
| 2004 |
Albrecht BK, Williams RM. A concise, total synthesis of the TMC-95A/B proteasome inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 101: 11949-54. PMID 15163792 DOI: 10.1073/Pnas.0308432101 |
0.403 |
|
| 2004 |
Jennewein S, Long RM, Williams RM, Croteau R. Cytochrome p450 taxadiene 5alpha-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis. Chemistry & Biology. 11: 379-87. PMID 15123267 DOI: 10.1016/J.Chembiol.2004.02.022 |
0.37 |
|
| 2004 |
Judd TC, Williams RM. A concise total synthesis of (+)-FR900482 and (+)-FR66979. The Journal of Organic Chemistry. 69: 2825-30. PMID 15074934 DOI: 10.1021/Jo035828T |
0.427 |
|
| 2004 |
Shaaban H, Giakas G, Bolton M, Williams R, Scheker LR, Lees VC. The distal radioulnar joint as a load-bearing mechanism--a biomechanical study. The Journal of Hand Surgery. 29: 85-95. PMID 14751110 DOI: 10.1016/j.jhsa.2003.10.020 |
0.304 |
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| 2003 |
Williams RM, Ducept P. Interstrand cross-linking of DNA by FK317 and its deacetylated metabolites FR70496 and FR157471. Biochemistry. 42: 14696-701. PMID 14661983 DOI: 10.1021/Bi035202X |
0.366 |
|
| 2003 |
Gray CR, Sanz-Cervera JF, Silks LA, Williams RM. Studies on the biosynthesis of asperparaline A: origin of the spirosuccinimde ring system. Journal of the American Chemical Society. 125: 14692-3. PMID 14640629 DOI: 10.1021/Ja037687I |
0.388 |
|
| 2003 |
Williams RM, Cao J, Tsujishima H, Cox RJ. Asymmetric, stereocontrolled total synthesis of paraherquamide A. Journal of the American Chemical Society. 125: 12172-8. PMID 14519003 DOI: 10.1021/Ja036713+ |
0.429 |
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| 2003 |
Aoyagi Y, Saitoh Y, Ueno T, Horiguchi M, Takeya K, Williams RM. Lipase TL-mediated kinetic tesolution of 5-benzyloxy-1-tert-butyldimethylsilyloxy-2-pentanol at low temperature: concise asymmetric synthesis of both enantiomers of a piperazic acid derivative. The Journal of Organic Chemistry. 68: 6899-904. PMID 12946129 DOI: 10.1021/Jo034441N |
0.367 |
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| 2003 |
Onishi T, Sebahar PR, Williams RM. Concise, asymmetric total synthesis of spirotryprostatin A. Organic Letters. 5: 3135-7. PMID 12917000 DOI: 10.1021/Ol0351910 |
0.418 |
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| 2003 |
Stocking EM, Williams RM. Chemistry and biology of biosynthetic Diels-Alder reactions. Angewandte Chemie (International Ed. in English). 42: 3078-115. PMID 12866094 DOI: 10.1002/Anie.200200534 |
0.387 |
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| 2003 |
DeMong DE, Williams RM. Asymmetric synthesis of (2S,3R)-capreomycidine and the total synthesis of capreomycin IB. Journal of the American Chemical Society. 125: 8561-5. PMID 12848564 DOI: 10.1021/Ja0351241 |
0.394 |
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| 2003 |
Jin W, Metobo S, Williams RM. Synthetic studies on ecteinascidin-743: constructing a versatile pentacyclic intermediate for the synthesis of ecteinascidins and saframycins. Organic Letters. 5: 2095-8. PMID 12790537 DOI: 10.1021/Ol034575N |
0.411 |
|
| 2003 |
Jennewein S, Rithner CD, Williams RM, Croteau R. Taxoid metabolism: Taxoid 14beta-hydroxylase is a cytochrome P450-dependent monooxygenase. Archives of Biochemistry and Biophysics. 413: 262-70. PMID 12729625 DOI: 10.1016/S0003-9861(03)00090-0 |
0.348 |
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| 2003 |
Coyle CM, Vogel KM, Rush TS, Kozlowski PM, Williams R, Spiro TG, Dou Y, Ikeda-Saito M, Olson JS, Zgierski MZ. FeNO structure in distal pocket mutants of myoglobin based on resonance Raman spectroscopy. Biochemistry. 42: 4896-903. PMID 12718530 DOI: 10.1021/Bi026395B |
0.328 |
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| 2003 |
Pain DJ, Meharg A, Sinclair G, Powell N, Finnie J, Williams R, Hilton G. Levels of cadmium and zinc in soil and plants following the toxic spill from a pyrite mine, Aznalcollar, Spain. Ambio. 32: 52-7. PMID 12691492 DOI: 10.1579/0044-7447-32.1.52 |
0.324 |
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| 2003 |
Allan G, Campen C, Hodgen G, Williams R, Charnock-Jones DS, Wan J, Erlander M, Palmer S. Identification of genes with differential regulation in primate endometrium during the proliferative and secretory phases of the cycle. Endocrine Research. 29: 53-65. PMID 12665318 DOI: 10.1081/erc-120018676 |
0.322 |
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| 2003 |
Domingo LR, Zaragozá RJ, Williams RM. Studies on the biosynthesis of paraherquamide A and VM99955. A theoretical study of intramolecular Diels-Alder cycloaddition. The Journal of Organic Chemistry. 68: 2895-902. PMID 12662067 DOI: 10.1021/Jo020564G |
0.396 |
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| 2003 |
Mundorf T, Williams R, Whitcup S, Felix C, Batoosingh A. A 3-month comparison of efficacy and safety of brimonidine-purite 0.15% and brimonidine 0.2% in patients with glaucoma or ocular hypertension. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 19: 37-44. PMID 12648302 DOI: 10.1089/108076803762718097 |
0.313 |
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| 2003 |
Ketchum RE, Rithner CD, Qiu D, Kim YS, Williams RM, Croteau RB. Taxus metabolomics: methyl jasmonate preferentially induces production of taxoids oxygenated at C-13 in Taxus x media cell cultures. Phytochemistry. 62: 901-9. PMID 12590117 DOI: 10.1016/S0031-9422(02)00711-2 |
0.347 |
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| 2003 |
Williams RM, Cox RJ. Paraherquamides, brevianamides, and asperparalines: laboratory synthesis and biosynthesis. An interim report. Accounts of Chemical Research. 36: 127-39. PMID 12589698 DOI: 10.1021/Ar020229E |
0.42 |
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| 2003 |
Albrecht BK, Williams RM. A concise formal total synthesis of TMC-95A/B proteasome inhibitors. Organic Letters. 5: 197-200. PMID 12529139 DOI: 10.1021/Ol0272545 |
0.394 |
|
| 2003 |
Griffith DC, Harford L, Williams R, Lee VJ, Dudley MN. In vivo antibacterial activity of RWJ-54428, a new cephalosporin with activity against gram-positive bacteria. Antimicrobial Agents and Chemotherapy. 47: 43-7. PMID 12499167 DOI: 10.1128/AAC.47.1.43-47.2003 |
0.33 |
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| 2002 |
Morris I, Williams R. Research Strategies for Orphan G-Protein-Coupled Receptors. Drug News & Perspectives. 15: 249-252. PMID 12677209 |
0.329 |
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| 2002 |
Judd TC, Williams RM. Concise enantioselective synthesis of (+)-FR66979 and (+)-FR900482: dimethyldioxirane-mediated construction of the hydroxylamine hemiketal. Angewandte Chemie (International Ed. in English). 41: 4683-5. PMID 12481325 DOI: 10.1002/Anie.200290015 |
0.397 |
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| 2002 |
Eckman RE, Williams R, Nagoshi C. Marital assortment for genetic similarity. Journal of Biosocial Science. 34: 511-23. PMID 12395866 DOI: 10.1017/S0021932002005114 |
0.325 |
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| 2002 |
Davies PD, Lado A, Northway R, Bennett G, Williams R, Moseley L, Mead D. An evaluation of student nurses experiences of being a researcher in a mental health research project. Nurse Education Today. 22: 518-26. PMID 12384032 |
0.323 |
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| 2002 |
Judd TC, Williams RM. Synthesis and DNA cross-linking of a phototriggered FR900482 mitosene progenitor. Organic Letters. 4: 3711-4. PMID 12375925 DOI: 10.1021/Ol0266774 |
0.368 |
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| 2002 |
Williams R, Mackway-Jones K. Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. White cell count and diagnosing appendicitis in adults. Emergency Medicine Journal : Emj. 19: 429-30. PMID 12204994 DOI: 10.1136/emj.19.5.429 |
0.338 |
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| 2002 |
Williams R, Mackway-Jones K. Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. White cell count and diagnosing appendicitis in children. Emergency Medicine Journal : Emj. 19: 428-9. PMID 12204992 DOI: 10.1136/emj.19.5.428 |
0.336 |
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| 2002 |
Jain RP, Williams RM. Asymmetric synthesis of (+)-negamycin. The Journal of Organic Chemistry. 67: 6361-5. PMID 12201754 DOI: 10.1021/Jo025636I |
0.407 |
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| 2002 |
Hainer JW, Sherrard DJ, Swan SK, Barrett JS, Assaid CA, Fossler MJ, Cox DS, Williams RM, Pittenger AL, Stephenson CA, Hua TA. Intravenous and subcutaneous weight-based dosing of the low molecular weight heparin tinzaparin (Innohep) in end-stage renal disease patients undergoing chronic hemodialysis. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 40: 531-8. PMID 12200805 DOI: 10.1053/Ajkd.2002.34911 |
0.313 |
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| 2002 |
Williams R. Drug reps are marketers, period Health Affairs. 21: 297-298; discussion . PMID 12117147 |
0.311 |
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| 2002 |
Horiguchi T, Rithner CD, Croteau R, Williams RM. Studies on taxol biosynthesis. Preparation of taxa-4(20),11(12)-dien-5 alpha-acetoxy-10 beta-ol by deoxygenation of a taxadiene tetraacetate obtained from Japanese yew. The Journal of Organic Chemistry. 67: 4901-3. PMID 12098303 DOI: 10.1021/Jo025679Z |
0.373 |
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| 2002 |
Shea B, Belmont C, Williams R. Communication, standards, and technology. HCA creates a new system to reduce medical errors. Health Forum Journal. 45: 34-5. PMID 12055908 |
0.307 |
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| 2002 |
Williams RM. Total synthesis and biosynthesis of the paraherquamides: An intriguing story of the biological Diels-Alder construction Chemical and Pharmaceutical Bulletin. 50: 711-740. PMID 12045324 DOI: 10.1248/Cpb.50.711 |
0.399 |
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| 2002 |
Scott JD, Williams RM. Chemistry and biology of the tetrahydroisoquinoline antitumor antibiotics. Chemical Reviews. 102: 1669-730. PMID 11996547 DOI: 10.1021/Cr010212U |
0.338 |
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| 2002 |
Beckerbauer L, Tepe JJ, Eastman RA, Mixter PF, Williams RM, Reeves R. Differential effects of FR900482 and FK317 on apoptosis, IL-2 gene expression, and induction of vascular leak syndrome. Chemistry & Biology. 9: 427-41. PMID 11983332 DOI: 10.1016/S1074-5521(02)00122-9 |
0.346 |
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| 2002 |
Scott JD, Williams RM. Total synthesis of (-)-tetrazomine. Determination of the stereochemistry of tetrazomine and the synthesis and biological activity of tetrazomine analogues. Journal of the American Chemical Society. 124: 2951-6. PMID 11902886 DOI: 10.1021/Ja0174027 |
0.426 |
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| 2002 |
Rehme PA, Williams R, Grabenstein J. Ambulatory medical visits among anthrax-vaccinated and unvaccinated personnel after return from southwest Asia. Military Medicine. 167: 205-10. PMID 11901567 |
0.316 |
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| 2002 |
Sanz-Cervera JF, Williams RM. Asymmetric total synthesis of (-)-VM55599: establishment of the absolute stereochemistry and biogenetic implications. Journal of the American Chemical Society. 124: 2556-9. PMID 11890806 DOI: 10.1021/Ja017425L |
0.422 |
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| 2002 |
Schnorr J, Oehninger S, Toner J, Hsiu J, Lanzendorf S, Williams R, Hodgen G. Functional studies of subcutaneous ovarian transplants in non-human primates: Steroidogenesis, endometrial development, ovulation, menstrual patterns and gamete morphology Human Reproduction. 17: 612-619. PMID 11870112 DOI: 10.1093/Humrep/17.3.612 |
0.305 |
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| 2002 |
Gable K, Han G, Monaghan E, Bacikova D, Natarajan M, Williams R, Dunn TM. Mutations in the yeast LCB1 and LCB2 genes, including those corresponding to the hereditary sensory neuropathy type I mutations, dominantly inactivate serine palmitoyltransferase. The Journal of Biological Chemistry. 277: 10194-200. PMID 11781309 DOI: 10.1074/jbc.M107873200 |
0.329 |
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| 2001 |
Scott JD, Williams RM. Total Synthesis of (-)-Tetrazomine and Determination of Its Stereochemistry. Angewandte Chemie (International Ed. in English). 40: 1463-1465. PMID 29712345 DOI: 10.1002/1521-3773(20010417)40:8<1463::Aid-Anie1463>3.0.Co;2-8 |
0.418 |
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| 2001 |
Scott JD, Williams RM. Total Synthesis of (-)-Tetrazomine and Determination of Its Stereochemistry This work was supported by the National Institutes of Health (Grant CA85419). We are grateful to Yamanouchi Pharmaceutical Co. for providing a generous gift of natural tetrazomine. Angewandte Chemie (International Ed. in English). 40: 1463-1465. PMID 11317303 DOI: 10.1002/1521-3773(20010417)40:8<1463::AID-ANIE1463>3.0.CO;2-8 |
0.357 |
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| 2001 |
Stocking EM, Sanz-Cervera JF, Williams RM. Studies on the Biosynthesis of Paraherquamide: Synthesis and Incorporation of a Hexacyclic Indole Derivative as an Advanced Metabolite This work was supported by the National Institutes of Health (Grant no. CA70375 to R.M.W.). We wish to acknowledge the American Chemical Society Division of Organic Chemistry Fellowship (sponsored by SmithKline Beecham) and the Pharmacia-Upjohn Company for financial support (to E.M.S.). Mass spectra were obtained on instruments supported by the National Institutes of Health Shared Instrumentation Grant (No. GM49631). We also wish to thank Professor Dean Crick of the Department of Microbiology at Colorado State University for helpful discussions. J.F.S.-C. thanks the DGICYT of Spain for a research grant (project no. PB98-1438). Angewandte Chemie (International Ed. in English). 40: 1296-1298. PMID 11301457 DOI: 10.1002/1521-3773(20010401)40:7<1296::Aid-Anie1296>3.0.Co;2-G |
0.355 |
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| 1999 |
Stocking EM, Sanz-Cervera JF, Williams RM. Reverse versus Normal Prenyl Transferases in Paraherquamide Biosynthesis Exhibit Distinct Facial Selectivities. Angewandte Chemie (International Ed. in English). 38: 786-789. PMID 29711799 DOI: 10.1002/(Sici)1521-3773(19990315)38:6<786::Aid-Anie786>3.0.Co;2-7 |
0.356 |
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| 1998 |
Rajski SR, Williams RM. DNA Cross-Linking Agents as Antitumor Drugs. Chemical Reviews. 98: 2723-2796. PMID 11848977 DOI: 10.1021/Cr9800199 |
0.328 |
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