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Richard Fishel - Publications

Affiliations: 
Biophysics Ohio State University, Columbus, Columbus, OH 
Area:
General Biophysics
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141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Senavirathne G, London J, Gardner A, Fishel R, Yoder KE. DNA strand breaks and gaps target retroviral intasome binding and integration. Nature Communications. 14: 7072. PMID 37923737 DOI: 10.1038/s41467-023-42641-4  0.798
2022 Yang XW, Han XP, Han C, London J, Fishel R, Liu J. MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair. Nature Communications. 13: 5808. PMID 36192430 DOI: 10.1038/s41467-022-33479-3  0.852
2022 Britton BM, London JA, Martin-Lopez J, Jones ND, Liu J, Lee JB, Fishel R. Exploiting the Distinctive Properties of the Bacterial and Human MutS Homolog Sliding Clamps on Mismatched DNA. The Journal of Biological Chemistry. 102505. PMID 36126773 DOI: 10.1016/j.jbc.2022.102505  0.823
2021 Crocker K, London J, Medina A, Fishel R, Bundschuh R. Evolutionary advantage of a dissociative search mechanism in DNA mismatch repair. Physical Review. E. 103: 052404. PMID 34134264 DOI: 10.1103/PhysRevE.103.052404  0.775
2021 Fishel R. Mismatch repair: Choreographing accurate strand excision. Current Biology : Cb. 31: R293-R296. PMID 33756142 DOI: 10.1016/j.cub.2021.02.001  0.355
2021 London J, Martín-López J, Yang I, Liu J, Lee JB, Fishel R. Linker domain function predicts pathogenic MLH1 missense variants. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33619096 DOI: 10.1073/pnas.2019215118  0.787
2019 Liu J, Lee R, Britton BM, London JA, Yang K, Hanne J, Lee JB, Fishel R. MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair. Nature Communications. 10: 5294. PMID 31757945 DOI: 10.1038/S41467-019-13191-5  0.842
2019 Mackler RM, Jones ND, Gardner AM, Lopez MA, Howard CJ, Fishel R, Yoder KE. Nucleosome DNA unwrapping does not affect prototype foamy virus integration efficiency or site selection. Plos One. 14: e0212764. PMID 30865665 DOI: 10.1371/Journal.Pone.0212764  0.528
2019 Liu J, Lee R, Britton B, London J, Hanne J, Lee J, Fishel R. DNA Mismatch Repair Relies Entirely on Stochastic Transactions Biophysical Journal. 116: 73a-74a. DOI: 10.1016/J.Bpj.2018.11.439  0.84
2018 Hanne J, Britton BM, Park J, Liu J, Martin-Lopez J, Jones N, Schoffner M, Klajner P, Bundschuh R, Lee JB, Fishel R. MutS homolog sliding clamps shield the DNA from binding proteins. The Journal of Biological Chemistry. PMID 30072380 DOI: 10.1016/J.Bpj.2018.11.447  0.844
2018 Liu J, Lee JB, Fishel R. Stochastic Processes and Component Placticity Governing DNA Mismatch Repair. Journal of Molecular Biology. PMID 29864444 DOI: 10.1016/J.Jmb.2018.05.039  0.766
2018 Kim D, Fishel R, Lee JB. Coordinating Multi-Protein Mismatch Repair by Managing Diffusion Mechanics on the DNA. Journal of Molecular Biology. PMID 29792877 DOI: 10.1016/J.Jmb.2018.05.032  0.568
2018 Kar A, Jones N, Arat NÖ, Fishel R, Griffith J. Long repeating (TTAGGG)n single stranded DNA self-condenses into compact beaded filaments stabilized by G-quadruplex formation. The Journal of Biological Chemistry. PMID 29674319 DOI: 10.1074/Jbc.Ra118.002158  0.439
2018 Martín-López J, Gasparini P, Coombes K, Croce CM, Boivin GP, Fishel R. Mutation of TGFβ-RII eliminates NSAID cancer chemoprevention. Oncotarget. 9: 12554-12561. PMID 29560090 DOI: 10.18632/Oncotarget.23792  0.77
2016 Liu J, Hanne J, Britton BM, Bennett J, Kim D, Lee JB, Fishel R. Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair. Nature. PMID 27851738 DOI: 10.1038/Nature20562  0.782
2016 Senavirathne G, Mahto SK, Hanne J, O'Brian D, Fishel R. Dynamic unwrapping of nucleosomes by HsRAD51 that includes sliding and rotational motion of histone octamers. Nucleic Acids Research. PMID 27738136 DOI: 10.1093/Nar/Gkw920  0.803
2016 Xu B, Soukup RJ, Jones CJ, Fishel R, Wozniak DJ. Pseudomonas aeruginosa AmrZ binds to four sites in the algD promoter, inducing DNA-AmrZ complex formation and transcriptional activation. Journal of Bacteriology. PMID 27185826 DOI: 10.1128/Jb.00259-16  0.387
2016 Jones ND, Lopez MA, Hanne J, Peake MB, Lee JB, Fishel R, Yoder KE. Retroviral intasomes search for a target DNA by 1D diffusion which rarely results in integration. Nature Communications. 7: 11409. PMID 27108531 DOI: 10.1038/Ncomms11409  0.493
2016 Fishel R, Heinen CD. Enhanced gene targeting to evaluate Lynch syndrome alterations. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035997 DOI: 10.1073/Pnas.1602650113  0.401
2016 Jeon Y, Kim D, Martín-López JV, Lee R, Oh J, Hanne J, Fishel R, Lee JB. Dynamic control of strand excision during human DNA mismatch repair. Proceedings of the National Academy of Sciences of the United States of America. PMID 26951673 DOI: 10.1073/Pnas.1523748113  0.844
2016 Jeon Y, Kim D, Martín-López J, Lee R, Oh J, Hanne J, Fishel R, Lee J. Single-Molecule Studies on EXOI Excision during DNA Mismatch Repair Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.408  0.843
2016 Fishel R, Lee JB. Mismatch repair Dna Replication, Recombination, and Repair: Molecular Mechanisms and Pathology. 305-339. DOI: 10.1007/978-4-431-55873-6_12  0.314
2015 Liu J, Hanne J, Britton BM, Shoffner M, Albers AE, Bennett J, Zatezalo R, Barfield R, Rabuka D, Lee JB, Fishel R. An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore. Scientific Reports. 5: 16883. PMID 26582263 DOI: 10.1038/Srep16883  0.641
2015 Xu B, Ju Y, Soukup RJ, Ramsey DM, Fishel R, Wysocki VH, Wozniak DJ. The Pseudomonas aeruginosa AmrZ C-terminal domain mediates tetramerization and is required for its activator and repressor functions. Environmental Microbiology Reports. PMID 26549743 DOI: 10.1111/1758-2229.12354  0.341
2015 Senavirathne G, Liu J, Lopez MA, Hanne J, Martin-Lopez J, Lee JB, Yoder KE, Fishel R. Widespread nuclease contamination in commonly used oxygen-scavenging systems. Nature Methods. 12: 901-902. PMID 26418762 DOI: 10.1038/Nmeth.3588  0.728
2015 Fishel R. Mismatch repair. The Journal of Biological Chemistry. 290: 26395-403. PMID 26354434 DOI: 10.1074/jbc.R115.660142  0.314
2015 Spies M, Fishel R. Mismatch repair during homologous and homeologous recombination. Cold Spring Harbor Perspectives in Biology. 7: a022657. PMID 25731766 DOI: 10.1101/Cshperspect.A022657  0.557
2015 Oh J, Kim D, Cho W, Liu J, Jergic S, Dixon N, Fishel R, Lee J. Interplay MutS with β Clamp on Mismatched DNA Biophysical Journal. 108: 69a. DOI: 10.1016/J.Bpj.2014.11.409  0.759
2014 Bennett GR, Peters R, Wang XH, Hanne J, Sobol RW, Bundschuh R, Fishel R, Yoder KE. Repair of oxidative DNA base damage in the host genome influences the HIV integration site sequence preference. Plos One. 9: e103164. PMID 25051054 DOI: 10.1371/Journal.Pone.0103164  0.406
2014 Lee JB, Cho WK, Park J, Jeon Y, Kim D, Lee SH, Fishel R. Single-molecule views of MutS on mismatched DNA. Dna Repair. 20: 82-93. PMID 24629484 DOI: 10.1016/J.Dnarep.2014.02.014  0.551
2014 Honda M, Okuno Y, Hengel SR, Martín-López JV, Cook CP, Amunugama R, Soukup RJ, Subramanyam S, Fishel R, Spies M. Mismatch repair protein hMSH2-hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediate. Proceedings of the National Academy of Sciences of the United States of America. 111: E316-25. PMID 24395779 DOI: 10.1073/Pnas.1312988111  0.818
2013 Amunugama R, Groden J, Fishel R. The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filament. Dna Repair. 12: 723-32. PMID 23810717 DOI: 10.1016/J.Dnarep.2013.05.005  0.812
2013 North JA, Amunugama R, Klajner M, Bruns AN, Poirier MG, Fishel R. ATP-dependent nucleosome unwrapping catalyzed by human RAD51. Nucleic Acids Research. 41: 7302-12. PMID 23757189 DOI: 10.1093/Nar/Gkt411  0.849
2013 Martín-López JV, Fishel R. The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome. Familial Cancer. 12: 159-68. PMID 23572416 DOI: 10.1007/S10689-013-9635-X  0.813
2012 North JA, Shimko JC, Javaid S, Mooney AM, Shoffner MA, Rose SD, Bundschuh R, Fishel R, Ottesen JJ, Poirier MG. Regulation of the nucleosome unwrapping rate controls DNA accessibility. Nucleic Acids Research. 40: 10215-27. PMID 22965129 DOI: 10.1093/Nar/Gks747  0.518
2012 Amunugama R, Fishel R. Homologous recombination in eukaryotes. Progress in Molecular Biology and Translational Science. 110: 155-206. PMID 22749146 DOI: 10.1016/B978-0-12-387665-2.00007-9  0.816
2012 Martín-López JV, Barrios Y, Medina-Arana V, Andújar M, Lee S, Gu L, Li GM, Rüschoff J, Salido E, Fishel R. The hMSH2(M688R) Lynch syndrome mutation may function as a dominant negative. Carcinogenesis. 33: 1647-54. PMID 22739024 DOI: 10.1093/Carcin/Bgs199  0.778
2012 Cho WK, Jeong C, Kim D, Chang M, Song KM, Hanne J, Ban C, Fishel R, Lee JB. ATP alters the diffusion mechanics of MutS on mismatched DNA. Structure (London, England : 1993). 20: 1264-74. PMID 22682745 DOI: 10.1016/J.Str.2012.04.017  0.513
2012 Amunugama R, He Y, Willcox S, Forties RA, Shim KS, Bundschuh R, Luo Y, Griffith J, Fishel R. RAD51 protein ATP cap regulates nucleoprotein filament stability. The Journal of Biological Chemistry. 287: 8724-36. PMID 22275364 DOI: 10.1074/Jbc.M111.239426  0.797
2011 Heinen CD, Cyr JL, Cook C, Punja N, Sakato M, Forties RA, Lopez JM, Hingorani MM, Fishel R. Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6. The Journal of Biological Chemistry. 286: 40287-95. PMID 21937421 DOI: 10.1074/Jbc.M111.297523  0.395
2011 Amunugama R, Fishel R. Subunit interface residues F129 and H294 of human RAD51 are essential for recombinase function. Plos One. 6: e23071. PMID 21857994 DOI: 10.1371/Journal.Pone.0023071  0.813
2011 Simon M, North JA, Shimko JC, Forties RA, Ferdinand MB, Manohar M, Zhang M, Fishel R, Ottesen JJ, Poirier MG. Histone fold modifications control nucleosome unwrapping and disassembly. Proceedings of the National Academy of Sciences of the United States of America. 108: 12711-6. PMID 21768347 DOI: 10.1073/Pnas.1106264108  0.427
2011 Forties RA, North JA, Javaid S, Tabbaa OP, Fishel R, Poirier MG, Bundschuh R. A quantitative model of nucleosome dynamics. Nucleic Acids Research. 39: 8306-13. PMID 21764779 DOI: 10.1093/Nar/Gkr422  0.471
2011 North JA, Javaid S, Ferdinand MB, Chatterjee N, Picking JW, Shoffner M, Nakkula RJ, Bartholomew B, Ottesen JJ, Fishel R, Poirier MG. Phosphorylation of histone H3(T118) alters nucleosome dynamics and remodeling. Nucleic Acids Research. 39: 6465-74. PMID 21576235 DOI: 10.1093/Nar/Gkr304  0.414
2011 Yoder KE, Espeseth A, Wang XH, Fang Q, Russo MT, Lloyd RS, Hazuda D, Sobol RW, Fishel R. The base excision repair pathway is required for efficient lentivirus integration. Plos One. 6: e17862. PMID 21448280 DOI: 10.1371/Journal.Pone.0017862  0.36
2011 Espeseth AS, Fishel R, Hazuda D, Huang Q, Xu M, Yoder K, Zhou H. siRNA screening of a targeted library of DNA repair factors in HIV infection reveals a role for base excision repair in HIV integration. Plos One. 6: e17612. PMID 21448273 DOI: 10.1371/Journal.Pone.0017612  0.389
2011 Pabla N, Ma Z, McIlhatton MA, Fishel R, Dong Z. hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis. The Journal of Biological Chemistry. 286: 10411-8. PMID 21285353 DOI: 10.1074/Jbc.M110.210989  0.533
2011 Jeong C, Cho WK, Song KM, Cook C, Yoon TY, Ban C, Fishel R, Lee JB. MutS switches between two fundamentally distinct clamps during mismatch repair. Nature Structural & Molecular Biology. 18: 379-85. PMID 21278758 DOI: 10.1038/Nsmb.2009  0.587
2011 Yoder KE, Roddick W, Hoellerbauer P, Fishel R. XPB mediated retroviral cDNA degradation coincides with entry to the nucleus. Virology. 410: 291-8. PMID 21167544 DOI: 10.1016/J.Virol.2010.11.016  0.344
2011 Lee J, Jeong C, Cho W, Ban C, Fishel R. Distinct Conformational Changes of MutS during DNA Mismatch Repair Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.1527  0.601
2010 Park J, Jeon Y, In D, Fishel R, Ban C, Lee JB. Single-molecule analysis reveals the kinetics and physiological relevance of MutL-ssDNA binding. Plos One. 5: e15496. PMID 21103398 DOI: 10.1371/Journal.Pone.0015496  0.516
2010 Valeri N, Gasparini P, Braconi C, Paone A, Lovat F, Fabbri M, Sumani KM, Alder H, Amadori D, Patel T, Nuovo GJ, Fishel R, Croce CM. MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2). Proceedings of the National Academy of Sciences of the United States of America. 107: 21098-103. PMID 21078976 DOI: 10.1073/Pnas.1015541107  0.305
2010 Simon M, Javaid S, Mooney A, Manohar M, Fishel R, Ottesen JJ, Poirier MG. Histone Post-Translational Modifications Buried within the Nucleosome DNA-Histone Interface Facilitate Nucleosome Disassembly Biophysical Journal. 98: 477a. DOI: 10.1016/J.Bpj.2009.12.2599  0.504
2009 Javaid S, Manohar M, Punja N, Mooney A, Ottesen JJ, Poirier MG, Fishel R. Nucleosome remodeling by hMSH2-hMSH6. Molecular Cell. 36: 1086-94. PMID 20064472 DOI: 10.1016/J.Molcel.2009.12.010  0.523
2009 Wang J, Jacob NK, Ladner KJ, Beg A, Perko JD, Tanner SM, Liyanarachchi S, Fishel R, Guttridge DC. RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair. Embo Reports. 10: 1272-8. PMID 19779484 DOI: 10.1038/Embor.2009.197  0.441
2009 Li LS, Morales JC, Veigl M, Sedwick D, Greer S, Meyers M, Wagner M, Fishel R, Boothman DA. DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets. British Journal of Pharmacology. 158: 679-92. PMID 19775280 DOI: 10.1111/J.1476-5381.2009.00423.X  0.499
2009 Manohar M, Mooney AM, North JA, Nakkula RJ, Picking JW, Edon A, Fishel R, Poirier MG, Ottesen JJ. Acetylation of histone H3 at the nucleosome dyad alters DNA-histone binding. The Journal of Biological Chemistry. 284: 23312-21. PMID 19520870 DOI: 10.1074/Jbc.M109.003202  0.378
2009 Charbonneau N, Amunugama R, Schmutte C, Yoder K, Fishel R. Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair. Cancer Biology & Therapy. 8: 1411-20. PMID 19483466 DOI: 10.4161/Cbt.8.14.8886  0.772
2009 Su X, Jacob NK, Amunugama R, Hsu PH, Fishel R, Freitas MA. Enrichment and characterization of histones by two-dimensional hydroxyapatite/reversed-phase liquid chromatography-mass spectrometry. Analytical Biochemistry. 388: 47-55. PMID 19454230 DOI: 10.1016/J.Ab.2009.01.033  0.753
2009 Mazurek A, Johnson CN, Germann MW, Fishel R. Sequence context effect for hMSH2-hMSH6 mismatch-dependent activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 4177-82. PMID 19237577 DOI: 10.1073/Pnas.0808572106  0.448
2008 Fishel R, Groden J. Harnessing mismatch repair to model sporadic cancers. Nature Methods. 5: 225-6. PMID 18309309 DOI: 10.1038/Nmeth0308-225  0.304
2008 Snowden T, Shim KS, Schmutte C, Acharya S, Fishel R. hMSH4-hMSH5 adenosine nucleotide processing and interactions with homologous recombination machinery. The Journal of Biological Chemistry. 283: 145-54. PMID 17977839 DOI: 10.1074/Jbc.M704060200  0.456
2007 McIlhatton MA, Tyler J, Burkholder S, Ruschoff J, Rigas B, Kopelovich L, Fishel R. Nitric oxide-donating aspirin derivatives suppress microsatellite instability in mismatch repair-deficient and hereditary nonpolyposis colorectal cancer cells. Cancer Research. 67: 10966-75. PMID 18006842 DOI: 10.1158/0008-5472.Can-07-2562  0.302
2007 Ikura T, Tashiro S, Kakino A, Shima H, Jacob N, Amunugama R, Yoder K, Izumi S, Kuraoka I, Tanaka K, Kimura H, Ikura M, Nishikubo S, Ito T, Muto A, ... ... Fishel R, et al. DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Molecular and Cellular Biology. 27: 7028-40. PMID 17709392 DOI: 10.1128/Mcb.00579-07  0.824
2007 Su X, Jacob NK, Amunugama R, Lucas DM, Knapp AR, Ren C, Davis ME, Marcucci G, Parthun MR, Byrd JC, Fishel R, Freitas MA. Liquid chromatography mass spectrometry profiling of histones. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 850: 440-54. PMID 17254850 DOI: 10.1016/J.Jchromb.2006.12.037  0.729
2006 Shim KS, Schmutte C, Yoder K, Fishel R. Defining the salt effect on human RAD51 activities. Dna Repair. 5: 718-30. PMID 16644292 DOI: 10.1016/J.Dnarep.2006.03.006  0.46
2006 Shim KS, Tombline G, Heinen CD, Charbonneau N, Schmutte C, Fishel R. Magnesium influences the discrimination and release of ADP by human RAD51. Dna Repair. 5: 704-17. PMID 16624636 DOI: 10.1016/J.Dnarep.2006.03.004  0.319
2006 Yoder K, Sarasin A, Kraemer K, McIlhatton M, Bushman F, Fishel R. The DNA repair genes XPB and XPD defend cells from retroviral infection. Proceedings of the National Academy of Sciences of the United States of America. 103: 4622-7. PMID 16537383 DOI: 10.1073/Pnas.0509828103  0.454
2005 Meyers M, Wagner MW, Mazurek A, Schmutte C, Fishel R, Boothman DA. DNA mismatch repair-dependent response to fluoropyrimidine-generated damage. The Journal of Biological Chemistry. 280: 5516-26. PMID 15611052 DOI: 10.1074/Jbc.M412105200  0.543
2005 Lenzi ML, Smith J, Snowden T, Kim M, Fishel R, Poulos BK, Cohen PE. Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes. American Journal of Human Genetics. 76: 112-27. PMID 15558497 DOI: 10.1086/427268  0.307
2004 Snowden T, Acharya S, Butz C, Berardini M, Fishel R. hMSH4-hMSH5 recognizes Holliday Junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomes. Molecular Cell. 15: 437-51. PMID 15304223 DOI: 10.1016/J.Molcel.2004.06.040  0.505
2004 Xie Y, Yang H, Cunanan C, Okamoto K, Shibata D, Pan J, Barnes DE, Lindahl T, McIlhatton M, Fishel R, Miller JH. Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Research. 64: 3096-102. PMID 15126346 DOI: 10.1158/0008-5472.Can-03-3834  0.418
2004 Shim KS, Schmutte C, Tombline G, Heinen CD, Fishel R. hXRCC2 enhances ADP/ATP processing and strand exchange by hRAD51. The Journal of Biological Chemistry. 279: 30385-94. PMID 15123651 DOI: 10.1074/Jbc.M306066200  0.499
2003 Acharya S, Foster PL, Brooks P, Fishel R. The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair. Molecular Cell. 12: 233-46. PMID 12887908 DOI: 10.1016/S1097-2765(03)00219-3  0.465
2003 Hansen LT, Thykjaer T, Ørntoft TF, Rasmussen LJ, Keller P, Spang-Thomsen M, Edmonston TB, Schmutte C, Fishel R, Petersen LN. The role of mismatch repair in small-cell lung cancer cells. European Journal of Cancer (Oxford, England : 1990). 39: 1456-67. PMID 12826050 DOI: 10.1016/S0959-8049(03)00306-X  0.334
2003 Fishel R, Acharya S, Berardini M, Bocker T, Charbonneau N, Cranston A, Gradia S, Guerrette S, Heinen CD, Mazurek A, Snowden T, Schmutte C, Shim KS, Tombline G, Wilson T. Signaling mismatch repair: the mechanics of an adenosine-nucleotide molecular switch. Cold Spring Harbor Symposia On Quantitative Biology. 65: 217-24. PMID 12760035 DOI: 10.1101/Sqb.2000.65.217  0.336
2002 Heinen CD, Schmutte C, Fishel R. DNA repair and tumorigenesis: lessons from hereditary cancer syndromes. Cancer Biology & Therapy. 1: 477-85. PMID 12496472 DOI: 10.4161/Cbt.1.5.160  0.539
2002 Heinen CD, Wilson T, Mazurek A, Berardini M, Butz C, Fishel R. HNPCC mutations in hMSH2 result in reduced hMSH2-hMSH6 molecular switch functions. Cancer Cell. 1: 469-78. PMID 12124176 DOI: 10.1016/S1535-6108(02)00073-9  0.372
2002 Slupianek A, Hoser G, Majsterek I, Bronisz A, Malecki M, Blasiak J, Fishel R, Skorski T. Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis. Molecular and Cellular Biology. 22: 4189-201. PMID 12024032 DOI: 10.1128/Mcb.22.12.4189-4201.2002  0.34
2002 Müller A, Fishel R. Mismatch repair and the hereditary non-polyposis colorectal cancer syndrome (HNPCC). Cancer Investigation. 20: 102-9. PMID 11852992 DOI: 10.1081/Cnv-120000371  0.354
2002 Tombline G, Heinen CD, Shim KS, Fishel R. Biochemical characterization of the human RAD51 protein. III. Modulation of DNA binding by adenosine nucleotides. The Journal of Biological Chemistry. 277: 14434-42. PMID 11839741 DOI: 10.1074/Jbc.M109917200  0.487
2002 Tombline G, Shim KS, Fishel R. Biochemical characterization of the human RAD51 protein. II. Adenosine nucleotide binding and competition. The Journal of Biological Chemistry. 277: 14426-33. PMID 11839740 DOI: 10.1074/Jbc.M109916200  0.341
2002 Tombline G, Fishel R. Biochemical characterization of the human RAD51 protein. I. ATP hydrolysis. The Journal of Biological Chemistry. 277: 14417-25. PMID 11839739 DOI: 10.1074/Jbc.M109915200  0.554
2002 Mazurek A, Berardini M, Fishel R. Activation of human MutS homologs by 8-oxo-guanine DNA damage. The Journal of Biological Chemistry. 277: 8260-6. PMID 11756455 DOI: 10.1074/Jbc.M111269200  0.426
2001 Slupianek A, Schmutte C, Tombline G, Nieborowska-Skorska M, Hoser G, Nowicki MO, Pierce AJ, Fishel R, Skorski T. BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance Molecular Cell. 8: 795-806. PMID 11684015 DOI: 10.1016/S1097-2765(01)00357-4  0.445
2001 Wang Q, Zhang H, Guerrette S, Chen J, Mazurek A, Wilson T, Slupianek A, Skorski T, Fishel R, Greene MI. Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1 Oncogene. 20: 4640-4649. PMID 11498787 DOI: 10.1038/Sj.Onc.1204625  0.422
2001 Murakumo Y, Ogura Y, Ishii H, Numata SI, Ichihara M, Croce CM, Fishel R, Takahashi M. Interactions in the Error-prone Postreplication Repair Proteins hREV1, hREV3, and hREV7 Journal of Biological Chemistry. 276: 35644-35651. PMID 11485998 DOI: 10.1074/Jbc.M102051200  0.512
2001 Schmutte C, Sadoff MM, Shim KS, Acharya S, Fishel R. The Interaction of DNA Mismatch Repair Proteins with Human Exonuclease I Journal of Biological Chemistry. 276: 33011-33018. PMID 11427529 DOI: 10.1074/Jbc.M102670200  0.574
2000 Wang Q, Zhang H, Fishel R, Greene MI. BRCA1 and cell signaling Oncogene. 19: 6152-6158. PMID 11156529 DOI: 10.1038/Sj.Onc.1203974  0.464
2000 Edmonston TB, Cuesta KH, Burkholder S, Barusevicius A, Rose D, Kovatich AJ, Boman B, Fry R, Fishel R, Palazzo JP. Colorectal carcinomas with high microsatellite instability: Defining a distinct immunologic and molecular entity with respect to prognostic markers Human Pathology. 31: 1506-1514. PMID 11150376 DOI: 10.1053/Hupa.2000.20383  0.329
2000 Berardini M, Mazurek A, Fishel R. The effect of O6-methylguanine DNA adducts on the adenosine nucleotide switch functions of hMSH2-hMSH6 and hMSH2-hMSH3 Journal of Biological Chemistry. 275: 27851-27857. PMID 10878012 DOI: 10.1074/Jbc.M003589200  0.536
2000 Jass JR, Iino H, Ruszkiewicz A, Painter D, Solomon MJ, Koorey DJ, Cohn D, Furlong KL, Walsh MD, Palazzo J, Edmonston TB, Fishel R, Young J, Leggett BA. Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum. Gut. 47: 43-9. PMID 10861263 DOI: 10.1136/Gut.47.1.43  0.408
2000 Kallal L, Fishel R. The GTP hydrolysis defect of the Saccharomyces cerevisiae mutant G-protein Gpa1(G50V) Yeast. 16: 387-400. PMID 10705368 DOI: 10.1002/(Sici)1097-0061(20000330)16:5<387::Aid-Yea525>3.0.Co;2-U  0.328
2000 Plaschke J, Kruppa C, Tischler R, Bocker T, Pistorius S, Dralle H, Rüschoff J, Saeger HD, Fishel R, Schackert HK. Sequence analysis of the mismatch repair gene hMSH6 in the germline of patients with familial and sporadic colorectal cancer International Journal of Cancer. 85: 606-613. PMID 10699937 DOI: 10.1002/(Sici)1097-0215(20000301)85:5<606::Aid-Ijc2>3.0.Co;2-B  0.341
2000 Murakumo Y, Roth T, Ishii H, Rasio D, Numata SI, Croce CM, Fishel R. A human REV7 homolog that interacts with the polymerase ζ catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2 Journal of Biological Chemistry. 275: 4391-4397. PMID 10660610 DOI: 10.1074/Jbc.275.6.4391  0.523
2000 Gradia S, Acharya S, Fishel R. The role of mismatched nucleotides in activating the hMSH2-hMSH6 molecular switch Journal of Biological Chemistry. 275: 3922-3930. PMID 10660545 DOI: 10.1074/Jbc.275.6.3922  0.463
1999 Schmutte C, Fishel R. Genomic instability: First step to carcinogenesis Anticancer Research. 19: 4665-4696. PMID 10697585  0.39
1999 Fishel R. Signaling mismatch repair in cancer Nature Medicine. 5: 1239-1241. PMID 10545986 DOI: 10.1038/15191  0.409
1999 Schmutte C, Tombline G, Rhiem K, Sadoff MM, Schmutzler R, Von Deimling A, Fishel R. Characterization of the human Rad51 genomic locus and examination of tumors with 15q14-15 loss of heterozygosity (LOH) Cancer Research. 59: 4564-4569. PMID 10493508  0.301
1999 Wilson T, Guerrette S, Fishel R. Dissociation of mismatch recognition and ATPase activity by hMSH2-hMSH3 Journal of Biological Chemistry. 274: 21659-21664. PMID 10419475 DOI: 10.1074/Jbc.274.31.21659  0.429
1999 Bocker T, Rüschoff J, Fishel R. Molecular diagnostics of cancer predisposition: Hereditary non-polyposis colorectal carcinoma and mismatch repair defects Biochimica Et Biophysica Acta - Reviews On Cancer. 1423. PMID 10382540 DOI: 10.1016/S0304-419X(99)00008-6  0.356
1999 Gradia S, Subramanian D, Wilson T, Acharya S, Makhov A, Griffith J, Fishel R. hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA Molecular Cell. 3: 255-261. PMID 10078208 DOI: 10.1016/S1097-2765(00)80316-0  0.582
1999 Simpkins SB, Bocker T, Swisher EM, Mutch DG, Gersell DJ, Kovatich AJ, Palazzo JP, Fishel R, Goodfellow PJ. MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers Human Molecular Genetics. 8: 661-666. PMID 10072435 DOI: 10.1093/Hmg/8.4.661  0.346
1999 Guerrette S, Acharya S, Fishel R. The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer Journal of Biological Chemistry. 274: 6336-6341. PMID 10037723 DOI: 10.1074/Jbc.274.10.6336  0.348
1999 Vora KA, Tumas-Brundage KM, Lentz VM, Cranston A, Fishel R, Manser T. Severe attenuation of the B cell immune response in Msh2-deficient mice Journal of Experimental Medicine. 189: 471-481. PMID 9927509 DOI: 10.1084/Jem.189.3.471  0.31
1998 Schmutte C, Marinescu RC, Sadoff MM, Guerrette S, Overhauser J, Fishel R. Human exonuclease I interacts with the mismatch repair protein hMSH2 Cancer Research. 58: 4537-4442. PMID 9788596  0.405
1998 Guerrette S, Wilson T, Gradia S, Fishel R. Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: Examination of mutations found in hereditary nonpolyposis colorectal cancer Molecular and Cellular Biology. 18: 6616-6623. PMID 9774676 DOI: 10.1128/Mcb.18.11.6616  0.339
1998 Rüschoff J, Wallinger S, Dietmaier W, Bocker T, Brockhoff G, Hofstädter F, Fishel R. Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection Proceedings of the National Academy of Sciences of the United States of America. 95: 11301-11306. PMID 9736731 DOI: 10.1073/Pnas.95.19.11301  0.302
1998 Fishel R. Mismatch repair, molecular switches, and signal transduction Genes and Development. 12: 2096-2101. PMID 9679053 DOI: 10.1101/Gad.12.14.2096  0.438
1997 Gradia S, Acharya S, Fishel R. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch Cell. 91: 995-1005. PMID 9428522 DOI: 10.1016/S0092-8674(00)80490-0  0.508
1997 Cranston A, Bocker T, Reitmair A, Palazzo J, Wilson T, Mak T, Fishel R. Female embryonic lethality in mice nullizygous for both Msh2 and p53 Nature Genetics. 17: 114-118. PMID 9288110 DOI: 10.1038/Ng0997-114  0.369
1997 Schmutte C, Baffa R, Veronese LM, Murakumo Y, Fishel R. Human thymine-DNA glycosylase maps at chromosome 12q22-q24.1: A region of high loss of heterozygosity in gastric cancer Cancer Research. 57: 3010-3015. PMID 9230216  0.37
1997 Pearson CE, Ewel A, Acharya S, Fishel RA, Sinden RR. Human MSH2 binds to trinucleotide repeat DNA structures associated with neurodegenerative diseases Human Molecular Genetics. 6: 1117-1123. PMID 9215683 DOI: 10.1093/Hmg/6.7.1117  0.411
1997 Rasio D, Murakumo Y, Robbins D, Roth T, Silver A, Negrini M, Schmidt C, Burczak J, Fishel R, Croce CM. Characterization of the human homologue of RAD54: a gene located on chromosome 1p32 at a region of high loss of heterozygosity in breast tumors. Cancer Research. 57: 2378-83. PMID 9192813  0.305
1997 Fishel R, Wilson T. MutS homologs in mammalian cells Current Opinion in Genetics and Development. 7: 105-113. PMID 9024626 DOI: 10.1016/S0959-437X(97)80117-7  0.412
1996 Fried LM, Koumenis C, Peterson SR, Green SL, van Zijl P, Allalunis-Turner J, Chen DJ, Fishel R, Giaccia AJ, Brown JM, Kirchgessner CU. The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction. Proceedings of the National Academy of Sciences of the United States of America. 93: 13825-30. PMID 8943020 DOI: 10.1073/Pnas.93.24.13825  0.547
1996 Acharya S, Wilson T, Gradia S, Kane MF, Guerrette S, Marsischky GT, Kolodner R, Fishel R. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6 Proceedings of the National Academy of Sciences of the United States of America. 93: 13629-13634. PMID 8942985 DOI: 10.1073/Pnas.93.24.13629  0.57
1996 Mello JA, Acharya S, Fishel R, Essigmann JM. The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin. Chemistry & Biology. 3: 579-89. PMID 8807890 DOI: 10.1016/S1074-5521(96)90149-0  0.555
1996 Mulrooney SB, Fishel RA, Hejna JA, Warner RC. Preparation of figure 8 and cruciform DNAs and their use in studies of the kinetics of branch migration. The Journal of Biological Chemistry. 271: 9648-59. PMID 8621640 DOI: 10.1074/Jbc.271.16.9648  0.363
1995 Fishel R, Kolodner RD. Identification of mismatch repair genes and their role in the development of cancer Current Opinion in Genetics and Development. 5: 382-395. PMID 7549435 DOI: 10.1016/0959-437X(95)80055-7  0.7
1994 Derbyshire MK, Epstein LH, Young CSH, Munz PL, Fishel R. Nonhomologous recombination in human cells Molecular and Cellular Biology. 14: 156-169. PMID 8264583 DOI: 10.1128/Mcb.14.1.156  0.547
1994 Sweezy MA, Fishel R. Multiple pathways leading to genomic instability and tumorigenesis Annals of the New York Academy of Sciences. 726: 165-177. PMID 8092674 DOI: 10.1111/J.1749-6632.1994.Tb52810.X  0.319
1994 Bigger CA, Cheh A, Latif F, Fishel R, Canella KA, Stafford GA, Yagi H, Jerina DM, Dipple A. DNA strand breaks induced by configurationally isomeric hydrocarbon diol epoxides. Drug Metabolism Reviews. 26: 287-99. PMID 8082571 DOI: 10.3109/03602539409029798  0.451
1994 Fishel R, Ewel A, Lee S, Lescoe MK, Griffith J. Binding of mismatched microsatellite DNA sequences by the human MSH2 protein Science. 266: 1403-1405. PMID 7973733 DOI: 10.1126/Science.7973733  0.594
1994 Fishel R, Ewel A, Lescoe MK. Purified Human MSH2 Protein Binds to DNA Containing Mismatched Nucleotides Cancer Research. 54: 5539-5542. PMID 7923193  0.447
1993 Fishel R, Lescoe MK, Rao MRS, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer Cell. 75: 1027-1038. PMID 8252616 DOI: 10.1016/0092-8674(93)90546-3  0.562
1991 Perkins AS, Fishel R, Jenkins NA, Copeland NG. Evi-1, a Murine Zinc Finger Proto-Oncogene, Encodes a Sequence-Specific DNA-Binding Protein Molecular and Cellular Biology. 11: 2665-2674. PMID 2017172 DOI: 10.1128/Mcb.11.5.2665  0.377
1991 Moore SP, Erdile L, Kelly T, Fishel R. The human homologous pairing protein HPP-1 is specifically stimulated by the cognate single-stranded binding protein hRP-A Proceedings of the National Academy of Sciences of the United States of America. 88: 9067-9071. PMID 1924369 DOI: 10.1073/Pnas.88.20.9067  0.476
1991 Fishel R, Derbyshire MK, Moore SP, Young CSH. Biochemical studies of homologous and nonhomologous recombination in human cells Biochimie. 73: 257-267. PMID 1653033 DOI: 10.1016/0300-9084(91)90211-I  0.397
1990 Krakzkiewicz-Dowjat A, Fishel R. recB recC-Dependent processing of heteroduplex DNA stimulates recombination of an adjacent gene in Escherichia coli Journal of Bacteriology. 172: 172-178. PMID 2403538  0.397
1990 Moore SP, Fishel R. Purification and characterization of a protein from human cells which promotes homologous pairing of DNA Journal of Biological Chemistry. 265: 11108-11117. PMID 2358453  0.465
1990 Fishel R, Anziano P, Rich A. [35] Z-DNA affinity chromatography Methods in Enzymology. 184: 319-327. DOI: 10.1016/0076-6879(90)84289-S  0.425
1989 Fishel R, Kolodner R. Gene conversion in Escherichia coli: The recF pathway for resolution of heteroduplex DNA Journal of Bacteriology. 171: 3046-3052. PMID 2656639 DOI: 10.1128/Jb.171.6.3046-3052.1989  0.625
1989 Moore SP, Rich A, Fishel R. The human recombination strand exchange process Genome. 31: 45-52. PMID 2591739 DOI: 10.1139/G89-012  0.56
1988 Fishel RA, Detmer K, Rich A. Identification of homologous pairing and strand-exchange activity from a human tumor cell line based on Z-DNA affinity chromatography Proceedings of the National Academy of Sciences of the United States of America. 85: 36-40. PMID 2963327 DOI: 10.1073/PNAS.85.1.36  0.467
1986 Fishel RA, Siegel EC, Kolodner R. Gene conversion in Escherichia coli. Resolution of heteroallelic mismatched nucleotides by co-repair Journal of Molecular Biology. 188: 147-157. PMID 3522919 DOI: 10.1016/0022-2836(86)90300-1  0.665
1985 Kolodner R, Fishel RA, Howard M. Genetic recombination of bacterial plasmid DNA: Effect of RecF pathway mutations on plasmid recombination in Escherichia coli Journal of Bacteriology. 163: 1060-1066. PMID 2993230 DOI: 10.1128/Jb.163.3.1060-1066.1985  0.505
1984 Fishel RA, Kolodner R. An Escherichia coli cell-free system that catalyzes the repair of symmetrically methylated heteroduplex DNA Cold Spring Harbor Symposia On Quantitative Biology. 603-609. PMID 6397315 DOI: 10.1101/Sqb.1984.049.01.068  0.615
1984 Fishel RA, Kolodner R. Escherichia coli strains containing mutations in the structural gene for topoisomerase I are recombination deficient Journal of Bacteriology. 160: 1168-1170. PMID 6094504 DOI: 10.1128/Jb.160.3.1168-1170.1984  0.467
1981 Fishel RA, James AA, Kolodner R. RecA-independent general genetic recombination of plasmids Nature. 294: 184-186. PMID 7029308 DOI: 10.1038/294184A0  0.642
1977 Wheeler FC, Fishel RA, Warner RC. Agarose gel electrophoresis of circular DNA of replicative form of bacteriophage G4. Analytical Biochemistry. 78: 260-75. PMID 848747 DOI: 10.1016/0003-2697(77)90031-8  0.39
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