Jun Seita, M.D., Ph.D. - Publications

2016- MIH RIKEN 
Deep Learning, Systems Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ambrosi TH, Marecic O, McArdle A, Sinha R, Gulati GS, Tong X, Wang Y, Steininger HM, Hoover MY, Koepke LS, Murphy MP, Sokol J, Seo EY, Tevlin R, Lopez M, ... ... Seita J, et al. Aged skeletal stem cells generate an inflammatory degenerative niche. Nature. PMID 34381212 DOI: 10.1038/s41586-021-03795-7  1
2020 Travaglini KJ, Nabhan AN, Penland L, Sinha R, Gillich A, Sit RV, Chang S, Conley SD, Mori Y, Seita J, Berry GJ, Shrager JB, Metzger RJ, Kuo CS, Neff N, et al. A molecular cell atlas of the human lung from single-cell RNA sequencing. Nature. PMID 33208946 DOI: 10.1038/s41586-020-2922-4  1
2020 Ambrosi TH, Goodnough LH, Steininger HM, Hoover MY, Kim E, Koepke LS, Marecic O, Zhao L, Seita J, Bishop JA, Gardner MJ, Chan CKF. Geriatric fragility fractures are associated with a human skeletal stem cell defect. Aging Cell. e13164. PMID 32537886 DOI: 10.1111/Acel.13164  1
2019 Hirano T, Nishide M, Nonaka N, Seita J, Ebina K, Sakurada K, Kumanogoh A. Development and validation of a deep-learning model for scoring of radiographic finger joint destruction in rheumatoid arthritis. Rheumatology Advances in Practice. 3: rkz047. PMID 31872173 DOI: 10.1093/Rap/Rkz047  0.2
2019 Tsai JM, Shoham M, Fernhoff NB, George BM, Marjon KD, McCracken MN, Kao KS, Sinha R, Volkmer AK, Miyanishi M, Seita J, Rinkevich Y, Weissman IL. Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation. Blood Advances. 3: 2713-2721. PMID 31519647 DOI: 10.1182/Bloodadvances.2018024026  1
2019 Zhu F, Feng M, Sinha R, Murphy MP, Luo F, Kao KS, Szade K, Seita J, Weissman IL. The GABA receptor GABRR1 is expressed on and functional in hematopoietic stem cells and megakaryocyte progenitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31451629 DOI: 10.1073/Pnas.1906251116  1
2019 Lu R, Czechowicz A, Seita J, Jiang D, Weissman IL. Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 30622181 DOI: 10.1073/Pnas.1801480116  1
2018 Rosental B, Kowarsky M, Seita J, Corey DM, Ishizuka KJ, Palmeri KJ, Chen SY, Sinha R, Okamoto J, Mantalas G, Manni L, Raveh T, Clarke DN, Tsai JM, Newman AM, et al. Complex mammalian-like haematopoietic system found in a colonial chordate. Nature. PMID 30518860 DOI: 10.1038/S41586-018-0783-X  1
2018 Tsai JM, Sinha R, Seita J, Fernhoff N, Christ S, Koopmans T, Krampitz GW, McKenna KM, Xing L, Sandholzer M, Sales JH, Shoham M, McCracken M, Joubert LM, Gordon SR, et al. Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers. Science Translational Medicine. 10. PMID 30487249 DOI: 10.1126/Scitranslmed.Aan6735  1
2018 Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, ... ... Seita J, et al. Identification of the Human Skeletal Stem Cell. Cell. 175: 43-56.e21. PMID 30241615 DOI: 10.1016/J.Cell.2018.07.029  1
2018 Zhu F, Feng M, Sinha R, Seita J, Mori Y, Weissman IL. Screening for genes that regulate the differentiation of human megakaryocytic lineage cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150396 DOI: 10.1073/Pnas.1805434115  1
2016 Weiskopf K, Schnorr PJ, Pang WW, Chao MP, Chhabra A, Seita J, Feng M, Weissman IL. Myeloid Cell Origins, Differentiation, and Clinical Implications. Microbiology Spectrum. 4. PMID 27763252 DOI: 10.1128/Microbiolspec.Mchd-0031-2016  1
2016 Chen JY, Miyanishi M, Wang SK, Yamazaki S, Sinha R, Kao KS, Seita J, Sahoo D, Nakauchi H, Weissman IL. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche. Nature. 530: 223-7. PMID 26863982 DOI: 10.1038/Nature16943  1
2015 Mori Y, Chen JY, Pluvinage JV, Seita J, Weissman IL. Prospective isolation of human erythroid lineage-committed progenitors. Proceedings of the National Academy of Sciences of the United States of America. 112: 9638-43. PMID 26195758 DOI: 10.1182/Blood.V122.21.3418.3418  1
2015 Chan CK, Seo EY, Chen JY, Lo D, McArdle A, Sinha R, Tevlin R, Seita J, Vincent-Tompkins J, Wearda T, Lu WJ, Senarath-Yapa K, Chung MT, Marecic O, Tran M, et al. Identification and specification of the mouse skeletal stem cell. Cell. 160: 285-98. PMID 25594184 DOI: 10.1016/J.Cell.2014.12.002  1
2015 Mori Y, Chen JY, Pluvinage JV, Seita J, Weissman IL. Prospective isolation of human erythroid lineage-committed progenitors Proceedings of the National Academy of Sciences of the United States of America. 112: 9638-9643. DOI: 10.1073/pnas.1512076112  1
2014 McArdle A, Chan C, Seita J, Senarath-Yapa K, Hu M, Walmsley GG, Zielins E, Atashroo D, Tevlin R, Weissman I, Longaker MT. Abstract 161: identification of cell-intrinsic mechanisms and differentially regulated genetic pathways responsible for the age-related functional decline in aged skeletal stem cells. Plastic and Reconstructive Surgery. 133: 178. PMID 25942271 DOI: 10.1097/01.Prs.0000444990.75431.F1  1
2014 Fathman JW, Fernhoff NB, Seita J, Chao C, Scarfone VM, Weissman IL, Inlay MA. Upregulation of CD11A on hematopoietic stem cells denotes the loss of long-term reconstitution potential. Stem Cell Reports. 3: 707-15. PMID 25418718 DOI: 10.1016/J.Stemcr.2014.09.007  1
2014 Ki S, Park D, Selden HJ, Seita J, Chung H, Kim J, Iyer VR, Ehrlich LI. Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution. Cell Reports. 9: 402-15. PMID 25284794 DOI: 10.1016/J.Celrep.2014.08.070  1
2014 Beerman I, Seita J, Inlay MA, Weissman IL, Rossi DJ. Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle. Cell Stem Cell. 15: 37-50. PMID 24813857 DOI: 10.1016/J.Stem.2014.04.016  1
2014 Inlay MA, Serwold T, Mosley A, Fathman JW, Dimov IK, Seita J, Weissman IL. Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development. Stem Cell Reports. 2: 457-72. PMID 24749071 DOI: 10.1016/J.Stemcr.2014.02.001  1
2014 Dimov IK, Lu R, Lee EP, Seita J, Sahoo D, Park SM, Weissman IL, Lee LP. Discriminating cellular heterogeneity using microwell-based RNA cytometry. Nature Communications. 5: 3451. PMID 24667995 DOI: 10.1038/Ncomms4451  1
2014 Ahn GO, Seita J, Hong BJ, Kim YE, Bok S, Lee CJ, Kim KS, Lee JC, Leeper NJ, Cooke JP, Kim HJ, Kim IH, Weissman IL, Brown JM. Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8. Proceedings of the National Academy of Sciences of the United States of America. 111: 2698-703. PMID 24497508 DOI: 10.1073/pnas.1320243111  1
2013 Miyanishi M, Mori Y, Seita J, Chen JY, Karten S, Chan CK, Nakauchi H, Weissman IL. Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? Stem Cell Reports. 1: 198-208. PMID 24052953 DOI: 10.1016/J.Stemcr.2013.07.001  1
2013 Chan CK, Lindau P, Jiang W, Chen JY, Zhang LF, Chen CC, Seita J, Sahoo D, Kim JB, Lee A, Park S, Nag D, Gong Y, Kulkarni S, Luppen CA, et al. Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12643-8. PMID 23858471 DOI: 10.1073/Pnas.1310212110  1
2013 Tseng D, Volkmer JP, Willingham SB, Contreras-Trujillo H, Fathman JW, Fernhoff NB, Seita J, Inlay MA, Weiskopf K, Miyanishi M, Weissman IL. Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response. Proceedings of the National Academy of Sciences of the United States of America. 110: 11103-8. PMID 23690610 DOI: 10.1073/Pnas.1305569110  1
2012 Seita J, Sahoo D, Rossi DJ, Bhattacharya D, Serwold T, Inlay MA, Ehrlich LI, Fathman JW, Dill DL, Weissman IL. Gene Expression Commons: an open platform for absolute gene expression profiling. Plos One. 7: e40321. PMID 22815738 DOI: 10.1371/Journal.Pone.0040321  1
2012 Drukker M, Tang C, Ardehali R, Rinkevich Y, Seita J, Lee AS, Mosley AR, Weissman IL, Soen Y. Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nature Biotechnology. 30: 531-42. PMID 22634564 DOI: 10.1038/Nbt.2239  1
2011 Fathman JW, Bhattacharya D, Inlay MA, Seita J, Karsunky H, Weissman IL. Identification of the earliest natural killer cell-committed progenitor in murine bone marrow. Blood. 118: 5439-47. PMID 21931117 DOI: 10.1182/Blood-2011-04-348912  1
2011 Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ. Nature Immunology. 12: 144-50. PMID 21170027 DOI: 10.1038/Ni.1976  1
2010 Seita J, Weissman IL. Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 640-53. PMID 20890962 DOI: 10.1002/wsbm.86  1
2010 Ji H, Ehrlich LI, Seita J, Murakami P, Doi A, Lindau P, Lee H, Aryee MJ, Irizarry RA, Kim K, Rossi DJ, Inlay MA, Serwold T, Karsunky H, Ho L, et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 467: 338-42. PMID 20720541 DOI: 10.1038/Nature09367  1
2010 Seita J, Rossi DJ, Weissman IL. Differential DNA damage response in stem and progenitor cells. Cell Stem Cell. 7: 145-7. PMID 20682442 DOI: 10.1016/J.Stem.2010.07.006  1
2010 Sahoo D, Seita J, Bhattacharya D, Inlay MA, Weissman IL, Plevritis SK, Dill DL. MiDReG: a method of mining developmentally regulated genes using Boolean implications. Proceedings of the National Academy of Sciences of the United States of America. 107: 5732-7. PMID 20231483 DOI: 10.1073/Pnas.0913635107  1
2009 Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes & Development. 23: 2376-81. PMID 19833765 DOI: 10.1101/Gad.1836009  1
2008 Chao MP, Seita J, Weissman IL. Establishment of a normal hematopoietic and leukemia stem cell hierarchy Cold Spring Harbor Symposia On Quantitative Biology. 73: 439-449. PMID 19022770 DOI: 10.1101/sqb.2008.73.031  1
2008 Seita J, Asakawa M, Ooehara J, Takayanagi S, Morita Y, Watanabe N, Fujita K, Kudo M, Mizuguchi J, Ema H, Nakauchi H, Yoshimoto T. Interleukin-27 directly induces differentiation in hematopoietic stem cells. Blood. 111: 1903-12. PMID 18042804 DOI: 10.1182/Blood-2007-06-093328  1
2007 Rossi DJ, Seita J, Czechowicz A, Bhattacharya D, Bryder D, Weissman IL. Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle (Georgetown, Tex.). 6: 2371-6. PMID 17700071 DOI: 10.4161/Cc.6.19.4759  1
2007 Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 447: 725-9. PMID 17554309 DOI: 10.1038/Nature05862  1
2007 Seita J, Ema H, Ooehara J, Yamazaki S, Tadokoro Y, Yamasaki A, Eto K, Takaki S, Takatsu K, Nakauchi H. Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 104: 2349-54. PMID 17284614 DOI: 10.1073/Pnas.0606238104  1
2006 Ema H, Morita Y, Yamazaki S, Matsubara A, Seita J, Tadokoro Y, Kondo H, Takano H, Nakauchi H. Adult mouse hematopoietic stem cells: purification and single-cell assays. Nature Protocols. 1: 2979-87. PMID 17406558 DOI: 10.1038/Nprot.2006.447  1
2005 Ema H, Sudo K, Seita J, Matsubara A, Morita Y, Osawa M, Takatsu K, Takaki S, Nakauchi H. Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice. Developmental Cell. 8: 907-14. PMID 15935779 DOI: 10.1016/J.Devcel.2005.03.019  1
1993 Carvalho L, Seita J. 13C Nmr Assignments Of D:B-Friedoolean-5-En-3β-Ol Natural Product Letters. 2: 57-60. DOI: 10.1080/10575639308043455  1
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