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Jun Seita, M.D., Ph.D. - Publications

Affiliations: 
2016- MIH RIKEN 
Area:
Deep Learning, Systems Biology
Website:
http://www.riken.jp/en/research/labs/mih/deep_learning/
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhao L, Lee AS, Sasagawa K, Sokol J, Wang Y, Ransom RC, Zhao X, Ma C, Steininger HM, Koepke LS, Borrelli MR, Brewer RE, Lee LLY, Huang X, Ambrosi TH, ... ... Seita J, et al. Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 37051932 DOI: 10.1161/ATVBAHA.122.317943  0.477
2023 Kobayashi M, Wei H, Yamanashi T, Azevedo Portilho N, Cornelius S, Valiente N, Nishida C, Cheng H, Latorre A, Zheng WJ, Kang J, Seita J, Shih DJ, Wu JQ, Yoshimoto M. HSC-independent definitive hematopoiesis persists into adult life. Cell Reports. 42: 112239. PMID 36906851 DOI: 10.1016/j.celrep.2023.112239  0.743
2022 Andrew TW, Koepke LS, Wang Y, Lopez M, Steininger H, Struck D, Boyko T, Ambrosi TH, Tong X, Sun Y, Gulati GS, Murphy MP, Marecic O, Telvin R, Schallmoser K, ... ... Seita J, et al. Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration. Nature Communications. 13: 6491. PMID 36310174 DOI: 10.1038/s41467-022-34063-5  0.641
2021 Sato Y, Oguchi A, Fukushima Y, Masuda K, Toriu N, Taniguchi K, Yoshikawa T, Cui X, Kondo M, Hosoi T, Komidori S, Shimizu Y, Fujita H, Jiang L, Kong Y, ... ... Seita J, et al. CD153-CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury. The Journal of Clinical Investigation. PMID 34813503 DOI: 10.1172/JCI146071  0.692
2021 Ambrosi TH, Marecic O, McArdle A, Sinha R, Gulati GS, Tong X, Wang Y, Steininger HM, Hoover MY, Koepke LS, Murphy MP, Sokol J, Seo EY, Tevlin R, Lopez M, ... ... Seita J, et al. Aged skeletal stem cells generate an inflammatory degenerative niche. Nature. PMID 34381212 DOI: 10.1038/s41586-021-03795-7  0.788
2020 Travaglini KJ, Nabhan AN, Penland L, Sinha R, Gillich A, Sit RV, Chang S, Conley SD, Mori Y, Seita J, Berry GJ, Shrager JB, Metzger RJ, Kuo CS, Neff N, et al. A molecular cell atlas of the human lung from single-cell RNA sequencing. Nature. PMID 33208946 DOI: 10.1038/s41586-020-2922-4  0.577
2019 Hirano T, Nishide M, Nonaka N, Seita J, Ebina K, Sakurada K, Kumanogoh A. Development and validation of a deep-learning model for scoring of radiographic finger joint destruction in rheumatoid arthritis. Rheumatology Advances in Practice. 3: rkz047. PMID 31872173 DOI: 10.1093/Rap/Rkz047  0.723
2019 Tsai JM, Shoham M, Fernhoff NB, George BM, Marjon KD, McCracken MN, Kao KS, Sinha R, Volkmer AK, Miyanishi M, Seita J, Rinkevich Y, Weissman IL. Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation. Blood Advances. 3: 2713-2721. PMID 31519647 DOI: 10.1182/Bloodadvances.2018024026  0.752
2019 Zhu F, Feng M, Sinha R, Murphy MP, Luo F, Kao KS, Szade K, Seita J, Weissman IL. The GABA receptor GABRR1 is expressed on and functional in hematopoietic stem cells and megakaryocyte progenitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31451629 DOI: 10.1073/Pnas.1906251116  0.757
2019 Lu R, Czechowicz A, Seita J, Jiang D, Weissman IL. Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 30622181 DOI: 10.1073/Pnas.1801480116  0.809
2018 Rosental B, Kowarsky M, Seita J, Corey DM, Ishizuka KJ, Palmeri KJ, Chen SY, Sinha R, Okamoto J, Mantalas G, Manni L, Raveh T, Clarke DN, Tsai JM, Newman AM, et al. Complex mammalian-like haematopoietic system found in a colonial chordate. Nature. PMID 30518860 DOI: 10.1038/S41586-018-0783-X  0.798
2018 Tsai JM, Sinha R, Seita J, Fernhoff N, Christ S, Koopmans T, Krampitz GW, McKenna KM, Xing L, Sandholzer M, Sales JH, Shoham M, McCracken M, Joubert LM, Gordon SR, et al. Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers. Science Translational Medicine. 10. PMID 30487249 DOI: 10.1126/Scitranslmed.Aan6735  0.76
2018 Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, ... ... Seita J, et al. Identification of the Human Skeletal Stem Cell. Cell. 175: 43-56.e21. PMID 30241615 DOI: 10.1016/J.Cell.2018.07.029  0.839
2018 Zhu F, Feng M, Sinha R, Seita J, Mori Y, Weissman IL. Screening for genes that regulate the differentiation of human megakaryocytic lineage cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150396 DOI: 10.1073/Pnas.1805434115  0.771
2017 Seita J, Weissman I, Kitano H. Identification of functional CMP in phenotypical CMP by in vivo, in vitro, and in silico experiments Experimental Hematology. 53: S67. DOI: 10.1016/j.exphem.2017.06.127  0.445
2016 Weiskopf K, Schnorr PJ, Pang WW, Chao MP, Chhabra A, Seita J, Feng M, Weissman IL. Myeloid Cell Origins, Differentiation, and Clinical Implications. Microbiology Spectrum. 4. PMID 27763252 DOI: 10.1128/Microbiolspec.Mchd-0031-2016  0.838
2016 Chen JY, Miyanishi M, Wang SK, Yamazaki S, Sinha R, Kao KS, Seita J, Sahoo D, Nakauchi H, Weissman IL. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche. Nature. 530: 223-7. PMID 26863982 DOI: 10.1038/Nature16943  0.801
2015 Mori Y, Chen JY, Pluvinage JV, Seita J, Weissman IL. Prospective isolation of human erythroid lineage-committed progenitors. Proceedings of the National Academy of Sciences of the United States of America. 112: 9638-43. PMID 26195758 DOI: 10.1182/Blood.V122.21.3418.3418  0.653
2015 Chan CK, Seo EY, Chen JY, Lo D, McArdle A, Sinha R, Tevlin R, Seita J, Vincent-Tompkins J, Wearda T, Lu WJ, Senarath-Yapa K, Chung MT, Marecic O, Tran M, et al. Identification and specification of the mouse skeletal stem cell. Cell. 160: 285-98. PMID 25594184 DOI: 10.1016/J.Cell.2014.12.002  0.832
2015 Mori Y, Chen JY, Pluvinage JV, Seita J, Weissman IL. Prospective isolation of human erythroid lineage-committed progenitors Proceedings of the National Academy of Sciences of the United States of America. 112: 9638-9643. DOI: 10.1073/pnas.1512076112  0.495
2014 McArdle A, Chan C, Seita J, Senarath-Yapa K, Hu M, Walmsley GG, Zielins E, Atashroo D, Tevlin R, Weissman I, Longaker MT. Abstract 161: identification of cell-intrinsic mechanisms and differentially regulated genetic pathways responsible for the age-related functional decline in aged skeletal stem cells. Plastic and Reconstructive Surgery. 133: 178. PMID 25942271 DOI: 10.1097/01.Prs.0000444990.75431.F1  0.717
2014 Fathman JW, Fernhoff NB, Seita J, Chao C, Scarfone VM, Weissman IL, Inlay MA. Upregulation of CD11A on hematopoietic stem cells denotes the loss of long-term reconstitution potential. Stem Cell Reports. 3: 707-15. PMID 25418718 DOI: 10.1016/J.Stemcr.2014.09.007  0.81
2014 Ki S, Park D, Selden HJ, Seita J, Chung H, Kim J, Iyer VR, Ehrlich LI. Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution. Cell Reports. 9: 402-15. PMID 25284794 DOI: 10.1016/J.Celrep.2014.08.070  0.752
2014 Beerman I, Seita J, Inlay MA, Weissman IL, Rossi DJ. Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle. Cell Stem Cell. 15: 37-50. PMID 24813857 DOI: 10.1016/J.Stem.2014.04.016  0.803
2014 Inlay MA, Serwold T, Mosley A, Fathman JW, Dimov IK, Seita J, Weissman IL. Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development. Stem Cell Reports. 2: 457-72. PMID 24749071 DOI: 10.1016/J.Stemcr.2014.02.001  0.826
2014 Dimov IK, Lu R, Lee EP, Seita J, Sahoo D, Park SM, Weissman IL, Lee LP. Discriminating cellular heterogeneity using microwell-based RNA cytometry. Nature Communications. 5: 3451. PMID 24667995 DOI: 10.1038/Ncomms4451  0.745
2014 Ahn GO, Seita J, Hong BJ, Kim YE, Bok S, Lee CJ, Kim KS, Lee JC, Leeper NJ, Cooke JP, Kim HJ, Kim IH, Weissman IL, Brown JM. Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8. Proceedings of the National Academy of Sciences of the United States of America. 111: 2698-703. PMID 24497508 DOI: 10.1073/pnas.1320243111  0.514
2014 Li Y, Seita J, Felsher DW, Dill D. Leukemia Cell Differentiation upon Targeted Therapy Revealed By a Systems Biology Approach Blood. 124: 5202-5202. DOI: 10.1182/Blood.V124.21.5202.5202  0.388
2014 Beerman I, Seita J, Inlay M, Weissman I, Rossi D. Hematopoietic stem cell quiescence attenuates DNA damage repair and response contributing to age-dependent DNA damage accumulation Experimental Hematology. 42: S24. DOI: 10.1016/J.Exphem.2014.07.083  0.793
2013 Miyanishi M, Mori Y, Seita J, Chen JY, Karten S, Chan CK, Nakauchi H, Weissman IL. Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? Stem Cell Reports. 1: 198-208. PMID 24052953 DOI: 10.1016/J.Stemcr.2013.07.001  0.81
2013 Chan CK, Lindau P, Jiang W, Chen JY, Zhang LF, Chen CC, Seita J, Sahoo D, Kim JB, Lee A, Park S, Nag D, Gong Y, Kulkarni S, Luppen CA, et al. Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12643-8. PMID 23858471 DOI: 10.1073/Pnas.1310212110  0.839
2013 Tseng D, Volkmer JP, Willingham SB, Contreras-Trujillo H, Fathman JW, Fernhoff NB, Seita J, Inlay MA, Weiskopf K, Miyanishi M, Weissman IL. Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response. Proceedings of the National Academy of Sciences of the United States of America. 110: 11103-8. PMID 23690610 DOI: 10.1073/Pnas.1305569110  0.757
2012 Seita J, Sahoo D, Rossi DJ, Bhattacharya D, Serwold T, Inlay MA, Ehrlich LI, Fathman JW, Dill DL, Weissman IL. Gene Expression Commons: an open platform for absolute gene expression profiling. Plos One. 7: e40321. PMID 22815738 DOI: 10.1371/Journal.Pone.0040321  0.744
2012 Drukker M, Tang C, Ardehali R, Rinkevich Y, Seita J, Lee AS, Mosley AR, Weissman IL, Soen Y. Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nature Biotechnology. 30: 531-42. PMID 22634564 DOI: 10.1038/Nbt.2239  0.843
2012 Lu R, Czechowicz A, Seita J, Weissman IL. Clonal Level Lineage Commitment of Mouse Hematopoietic Stem Cells in Vivo Blood. 120: 27-27. DOI: 10.1182/Blood.V120.21.27.27  0.814
2011 Fathman JW, Bhattacharya D, Inlay MA, Seita J, Karsunky H, Weissman IL. Identification of the earliest natural killer cell-committed progenitor in murine bone marrow. Blood. 118: 5439-47. PMID 21931117 DOI: 10.1182/Blood-2011-04-348912  0.798
2011 Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ. Nature Immunology. 12: 144-50. PMID 21170027 DOI: 10.1038/Ni.1976  0.457
2010 Seita J, Weissman IL. Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 640-53. PMID 20890962 DOI: 10.1002/wsbm.86  0.609
2010 Ji H, Ehrlich LI, Seita J, Murakami P, Doi A, Lindau P, Lee H, Aryee MJ, Irizarry RA, Kim K, Rossi DJ, Inlay MA, Serwold T, Karsunky H, Ho L, et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 467: 338-42. PMID 20720541 DOI: 10.1038/Nature09367  0.788
2010 Seita J, Rossi DJ, Weissman IL. Differential DNA damage response in stem and progenitor cells. Cell Stem Cell. 7: 145-7. PMID 20682442 DOI: 10.1016/J.Stem.2010.07.006  0.742
2010 Sahoo D, Seita J, Bhattacharya D, Inlay MA, Weissman IL, Plevritis SK, Dill DL. MiDReG: a method of mining developmentally regulated genes using Boolean implications. Proceedings of the National Academy of Sciences of the United States of America. 107: 5732-7. PMID 20231483 DOI: 10.1073/Pnas.0913635107  0.804
2010 Fathman J, Bhattacharya D, Inlay M, Seita J, Weissman I. Identification of the Earliest Committed Natural Killer Cell Progenitor in Murine Bone Marrow Clinical Immunology. 135: S133. DOI: 10.1016/J.Clim.2010.03.401  0.792
2009 Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes & Development. 23: 2376-81. PMID 19833765 DOI: 10.1101/Gad.1836009  0.811
2008 Chao MP, Seita J, Weissman IL. Establishment of a normal hematopoietic and leukemia stem cell hierarchy Cold Spring Harbor Symposia On Quantitative Biology. 73: 439-449. PMID 19022770 DOI: 10.1101/sqb.2008.73.031  0.638
2007 Rossi DJ, Seita J, Czechowicz A, Bhattacharya D, Bryder D, Weissman IL. Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle (Georgetown, Tex.). 6: 2371-6. PMID 17700071 DOI: 10.4161/Cc.6.19.4759  0.81
2007 Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 447: 725-9. PMID 17554309 DOI: 10.1038/Nature05862  0.805
2007 Seita J, Ema H, Ooehara J, Yamazaki S, Tadokoro Y, Yamasaki A, Eto K, Takaki S, Takatsu K, Nakauchi H. Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 104: 2349-54. PMID 17284614 DOI: 10.1073/Pnas.0606238104  0.386
2006 Ema H, Morita Y, Yamazaki S, Matsubara A, Seita J, Tadokoro Y, Kondo H, Takano H, Nakauchi H. Adult mouse hematopoietic stem cells: purification and single-cell assays. Nature Protocols. 1: 2979-87. PMID 17406558 DOI: 10.1038/Nprot.2006.447  0.43
2006 Ema H, Seita J, Ooehara J, Iseki A, Takano H, Nakauchi H. Adaptor Protein Lnk Negatively Controls the Likelihood of Self-Renewal in Hematopoietic Stem Cells. Blood. 108: 1316-1316. DOI: 10.1182/Blood.V108.11.1316.1316  0.388
2005 Ema H, Sudo K, Seita J, Matsubara A, Morita Y, Osawa M, Takatsu K, Takaki S, Nakauchi H. Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice. Developmental Cell. 8: 907-14. PMID 15935779 DOI: 10.1016/J.Devcel.2005.03.019  0.301
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