Year |
Citation |
Score |
2022 |
Thirmanne HN, Wu F, Janssens DH, Swanger J, Diab A, Feldman H, Amezquita RA, Gottardo R, Paddison PJ, Henikoff S, Clurman BE. Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations. Elife. 11. PMID 35225231 DOI: 10.7554/eLife.74338 |
0.356 |
|
2021 |
Khan OM, Almagro J, Nelson JK, Horswell S, Encheva V, Keyan KS, Clurman BE, Snijders AP, Behrens A. Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12. Nature Communications. 12: 2043. PMID 33824312 DOI: 10.1038/s41467-021-22319-5 |
0.374 |
|
2020 |
Chi Y, Carter JH, Swanger J, Mazin AV, Moritz RL, Clurman BE. A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation. Science Advances. 6: eaaz9899. PMID 32494624 DOI: 10.1126/Sciadv.Aaz9899 |
0.466 |
|
2020 |
Diab A, Swanger J, Gem H, Galloway D, Mendez E, Sidorova J, Clurman B. Abstract PR07: WEE1 inhibition triggers premature mitotic entry in HPV16-E6-expressing cells independent of p53 inactivation Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Aacrahns19-Pr07 |
0.363 |
|
2019 |
Loeb KR, Hughes BT, Fissel BM, Osteen NJ, Knoblaugh SE, Grim JE, Drury LJ, Sarver A, Dupuy AJ, Clurman BE. Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice. Scientific Reports. 9: 5488. PMID 30940846 DOI: 10.1038/S41598-019-41805-X |
0.383 |
|
2019 |
Dye KN, Welcker M, Clurman BE, Roman A, Galloway DA. Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP. Plos Pathogens. 15: e1007543. PMID 30689667 DOI: 10.1371/Journal.Ppat.1007543 |
0.316 |
|
2018 |
Davis RJ, Gönen M, Margineantu DH, Handeli S, Swanger J, Hoellerbauer P, Paddison PJ, Gu H, Raftery D, Grim JE, Hockenbery DM, Margolin AA, Clurman BE. Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735700 DOI: 10.1073/Pnas.1718338115 |
0.384 |
|
2018 |
Goyal N, Rossi MJ, Mazina OM, Chi Y, Moritz RL, Clurman BE, Mazin AV. RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions. Nature Communications. 9: 34. PMID 29295984 DOI: 10.1038/S41467-017-02497-X |
0.342 |
|
2017 |
Calses PC, Dhillon KK, Tucker N, Chi Y, Huang JW, Kawasumi M, Nghiem P, Wang Y, Clurman BE, Jacquemont C, Gafken PR, Sugasawa K, Saijo M, Taniguchi T. DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing. Cell Reports. 19: 162-174. PMID 28380355 DOI: 10.1016/J.Celrep.2017.03.021 |
0.307 |
|
2017 |
Davis RJ, Swanger J, Hughes BT, Clurman BE. The PP2A-B56 phosphatase opposes cyclin E autocatalytic degradation via site-specific dephosphorylation. Molecular and Cellular Biology. PMID 28137908 DOI: 10.1128/Mcb.00657-16 |
0.411 |
|
2017 |
Diab A, Chang X, Kao M, Clurman B, Galloway D, Eduardo M. Abstract 58: Therapeutically targeting the cell cycle in head and neck cancer Clinical Cancer Research. 23: 58-58. DOI: 10.1158/1557-3265.Aacrahns17-58 |
0.384 |
|
2017 |
Davis RJ, Swanger J, Clurman BE. Abstract 308: The PP2A-B56 phosphatase opposes cyclin E autocatalytic degradation via site-specific dephosphorylation Cancer Research. 77: 308-308. DOI: 10.1158/1538-7445.Am2017-308 |
0.333 |
|
2017 |
Clurman BE, Chi Y. Abstract 2341:In situlabelling identifies a novel landscape of nuclear CDK2 substrates Cancer Research. 77: 2341-2341. DOI: 10.1158/1538-7445.Am2017-2341 |
0.359 |
|
2016 |
Richards H, Zhao H, Hughes BT, Clurman BE. Abstract IA20: Exploiting CDK2-driven replication stress to repurpose cancer chemotherapy Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Ia20 |
0.387 |
|
2016 |
Toledo C, Yu D, Hoellerbauer P, Davis R, Basom R, Girard E, Corrin P, Bolouri H, Davison J, Zhang Q, Nam D, Lee J, Pollard S, Delrow J, Clurman B, et al. Abstract 4370: Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in patient-derived glioblastoma stem-like cells Cancer Research. 76: 4370-4370. DOI: 10.1158/1538-7445.Am2016-4370 |
0.364 |
|
2015 |
Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, ... ... Clurman BE, et al. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. Cell Reports. PMID 26673326 DOI: 10.1016/J.Celrep.2015.11.021 |
0.371 |
|
2015 |
Park E, Lee B, Clurman B, Lee K. NUP50 is necessary for the survival of primordial germ cells in mouse embryos. Reproduction (Cambridge, England). PMID 26515778 DOI: 10.1530/Rep-14-0649 |
0.325 |
|
2015 |
Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Bolouri H, Davison J, Zhang Q, Nam D, Lee J, Pollard SM, Zhu J, ... ... Clurman BE, et al. Abstract C159: Genome-wide CRISPR-Cas9 screens uncover therapeutic targets and tumor suppressor genes in glioblastoma multiforme Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C159 |
0.39 |
|
2015 |
Toledo C, Ding Y, Hoellerbauer P, Davis R, Basom R, Girard E, Corrin P, Delrow J, Clurman B, Olson J, Paddison P. ATPS-60COMPREHENSIVE IDENTIFICATION OF GLIOBLASTOMA MULTIFORME THERAPEUTIC TARGETS AND GROWTH SUPPRESSOR GENES USING GENE EDITING Neuro-Oncology. 17: v31.3-v31. DOI: 10.1093/Neuonc/Nov204.60 |
0.359 |
|
2014 |
Zhao H, Faltermeier CM, Mendelsohn L, Porter PL, Clurman BE, Roberts JM. Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy. Oncotarget. 5: 12704-14. PMID 25587029 DOI: 10.18632/Oncotarget.2871 |
0.346 |
|
2014 |
Davis RJ, Welcker M, Clurman BE. Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities. Cancer Cell. 26: 455-64. PMID 25314076 DOI: 10.1016/J.Ccell.2014.09.013 |
0.421 |
|
2014 |
Welcker M, Clurman BE. Oncoprotein ubiquitylation: dimers, degrons, and degradation. Cell Cycle (Georgetown, Tex.). 13: 1829-30. PMID 24866825 DOI: 10.4161/Cc.29325 |
0.522 |
|
2013 |
Welcker M, Larimore EA, Swanger J, Bengoechea-Alonso MT, Grim JE, Ericsson J, Zheng N, Clurman BE. Fbw7 dimerization determines the specificity and robustness of substrate degradation. Genes & Development. 27: 2531-6. PMID 24298052 DOI: 10.1101/Gad.229195.113 |
0.729 |
|
2013 |
Sancho R, Blake SM, Tendeng C, Clurman BE, Lewis J, Behrens A. Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions. Plos Biology. 11: e1001586. PMID 23776410 DOI: 10.1371/Journal.Pbio.1001586 |
0.388 |
|
2013 |
Hughes BT, Sidorova J, Swanger J, Monnat RJ, Clurman BE. Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation. Proceedings of the National Academy of Sciences of the United States of America. 110: 8954-9. PMID 23671119 DOI: 10.1073/Pnas.1302927110 |
0.408 |
|
2013 |
Pierce NW, Lee JE, Liu X, Sweredoski MJ, Graham RL, Larimore EA, Rome M, Zheng N, Clurman BE, Hess S, Shan SO, Deshaies RJ. Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins. Cell. 153: 206-15. PMID 23453757 DOI: 10.1016/J.Cell.2013.02.024 |
0.713 |
|
2013 |
Davis MA, Larimore EA, Fissel BM, Swanger J, Taatjes DJ, Clurman BE. The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator. Genes & Development. 27: 151-6. PMID 23322298 DOI: 10.1101/Gad.207720.112 |
0.724 |
|
2013 |
Hizli AA, Chi Y, Swanger J, Carter JH, Liao Y, Welcker M, Ryazanov AG, Clurman BE. Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase. Molecular and Cellular Biology. 33: 596-604. PMID 23184662 DOI: 10.1128/Mcb.01270-12 |
0.39 |
|
2012 |
Loeb KR, Hughes BT, Fissel BM, Choi YE, Pogosov G, Knoblaugh SE, Wood BL, Clurman BE. Sleeping Beauty Transposon Insertional Mutagenesis Identifies Drivers of Erythroid Leukemia in Mice. Blood. 120: 2407-2407. DOI: 10.1182/Blood.V120.21.2407.2407 |
0.401 |
|
2012 |
Larimore EA, Welcker M, Clurman BE. Abstract 2034: The Fbw7 tumor suppressor: Genetic and biochemical approaches to study a dimeric ubiquitin ligase Cancer Research. 72: 2034-2034. DOI: 10.1158/1538-7445.Am2012-2034 |
0.305 |
|
2012 |
Grim JE, Knoblaugh S, Hagar A, Hespelt J, Swanger J, Guthrie K, Small T, Grady WM, Nakayama K, Clurman BE. Abstract 1340: A mouse model of metastatic intestinal cancers associated with Fbw7- and p53-loss Cancer Research. 72: 1340-1340. DOI: 10.1158/1538-7445.Am2012-1340 |
0.337 |
|
2011 |
Sengupta T, Abraham G, Xu Y, Clurman BE, Minella AC. Hypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis. Molecular and Cellular Biology. 31: 3885-95. PMID 21746877 DOI: 10.1128/Mcb.05089-11 |
0.381 |
|
2011 |
Welcker M, Larimore EA, Frappier L, Clurman BE. Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3. Molecular and Cellular Biology. 31: 1214-24. PMID 21220517 DOI: 10.1128/Mcb.01347-10 |
0.746 |
|
2010 |
Chi Y, Clurman BE. Mass spectrometry-based identification of protein kinase substrates utilizing engineered kinases and thiophosphate labeling. Current Protocols in Chemical Biology. 2: 219-34. PMID 23839977 DOI: 10.1002/9780470559277.Ch100151 |
0.384 |
|
2008 |
Chi Y, Welcker M, Hizli AA, Posakony JJ, Aebersold R, Clurman BE. Identification of CDK2 substrates in human cell lysates. Genome Biology. 9: R149. PMID 18847512 DOI: 10.1186/Gb-2008-9-10-R149 |
0.454 |
|
2008 |
Liu H, Huang J, Wang J, Jiang S, Bailey AS, Goldman DC, Welcker M, Bedell V, Slovak ML, Clurman B, Thayer M, Fleming WH, Epner E. Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma. The Journal of Experimental Medicine. 205: 1843-58. PMID 18625744 DOI: 10.1084/Jem.20072102 |
0.355 |
|
2008 |
Grim JE, Gustafson MP, Hirata RK, Hagar AC, Swanger J, Welcker M, Hwang HC, Ericsson J, Russell DW, Clurman BE. Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase. The Journal of Cell Biology. 181: 913-20. PMID 18559665 DOI: 10.1083/Jcb.200802076 |
0.518 |
|
2008 |
Minella AC, Loeb KR, Knecht A, Welcker M, Varnum-Finney BJ, Bernstein ID, Roberts JM, Clurman BE. Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo. Genes & Development. 22: 1677-89. PMID 18559482 DOI: 10.1101/Gad.1650208 |
0.413 |
|
2008 |
Welcker M, Clurman BE. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nature Reviews. Cancer. 8: 83-93. PMID 18094723 DOI: 10.1038/Nrc2290 |
0.45 |
|
2007 |
Garrett-Engele CM, Tasch MA, Hwang HC, Fero ML, Perlmutter RM, Clurman BE, Roberts JM. A mechanism misregulating p27 in tumors discovered in a functional genomic screen. Plos Genetics. 3: e219. PMID 18069898 DOI: 10.1371/Journal.Pgen.0030219 |
0.401 |
|
2007 |
O'Neil J, Grim J, Strack P, Rao S, Tibbitts D, Winter C, Hardwick J, Welcker M, Meijerink JP, Pieters R, Draetta G, Sears R, Clurman BE, Look AT. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors. The Journal of Experimental Medicine. 204: 1813-24. PMID 17646409 DOI: 10.1084/Jem.20070876 |
0.381 |
|
2007 |
Besson A, Hwang HC, Cicero S, Donovan SL, Gurian-West M, Johnson D, Clurman BE, Dyer MA, Roberts JM. Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype. Genes & Development. 21: 1731-46. PMID 17626791 DOI: 10.1101/Gad.1556607 |
0.412 |
|
2007 |
Chen X, Barton LF, Chi Y, Clurman BE, Roberts JM. Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome. Molecular Cell. 26: 843-52. PMID 17588519 DOI: 10.1016/J.Molcel.2007.05.022 |
0.393 |
|
2007 |
Minella AC, Grim JE, Welcker M, Clurman BE. p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability Oncogene. 26: 6948-6953. PMID 17486057 DOI: 10.1038/Sj.Onc.1210518 |
0.39 |
|
2007 |
Welcker M, Clurman BE. Fbw7/hCDC4 dimerization regulates its substrate interactions. Cell Division. 2: 7. PMID 17298674 DOI: 10.1186/1747-1028-2-7 |
0.415 |
|
2007 |
Geng Y, Lee YM, Welcker M, Swanger J, Zagozdzon A, Winer JD, Roberts JM, Kaldis P, Clurman BE, Sicinski P. Kinase-independent function of cyclin E. Molecular Cell. 25: 127-39. PMID 17218276 DOI: 10.1016/J.Molcel.2006.11.029 |
0.383 |
|
2006 |
Gustafson MP, Xu C, Grim JE, Clurman BE, Knudsen BS. Regulation of cell proliferation in a stratified culture system of epithelial cells from prostate tissue. Cell and Tissue Research. 325: 263-76. PMID 16557385 DOI: 10.1007/S00441-005-0093-0 |
0.313 |
|
2006 |
Welcker M, Clurman B. Cell cycle: how cyclin E got its groove back. Current Biology : Cb. 15: R810-2. PMID 16213815 DOI: 10.1016/J.Cub.2005.09.018 |
0.385 |
|
2006 |
Grim JE, Sala O, Chung NG, Radich J, Varnum-Finney BJ, Bernstein ID, Clurman B. Notch Regulation by the Fbw7/hcdc4/Sel-10 Ubiquitin Ligase. Blood. 108: 1420-1420. DOI: 10.1182/Blood.V108.11.1420.1420 |
0.451 |
|
2006 |
Welcker M, Orian A, Jin J, Grim JA, Harper JW, Eisenman RN, Clurman BE. Erratum: The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation (Proceedings of the National Academy of Science of the United States of America (June 15, 2004) 101, 24 (9085-9090) DOI: 10.1073/pnas.0402770101) Proceedings of the National Academy of Sciences of the United States of America. 103. DOI: 10.1073/Pnas.0510298102 |
0.382 |
|
2005 |
Gustafson MP, Welcker M, Hwang HC, Clurman BE. Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins. Biochemical and Biophysical Research Communications. 338: 1359-67. PMID 16263084 DOI: 10.1016/J.Bbrc.2005.10.090 |
0.424 |
|
2005 |
Minella AC, Clurman BE. Mechanisms of tumor suppression by the SCF(Fbw7). Cell Cycle (Georgetown, Tex.). 4: 1356-9. PMID 16131838 DOI: 10.4161/Cc.4.10.2058 |
0.508 |
|
2005 |
Loeb KR, Kostner H, Firpo E, Norwood T, D Tsuchiya K, Clurman BE, Roberts JM. A mouse model for cyclin E-dependent genetic instability and tumorigenesis. Cancer Cell. 8: 35-47. PMID 16023597 DOI: 10.1016/J.Ccr.2005.06.010 |
0.387 |
|
2005 |
Minella AC, Welcker M, Clurman BE. Ras activity regulates cyclin E degradation by the Fbw7 pathway. Proceedings of the National Academy of Sciences of the United States of America. 102: 9649-54. PMID 15980150 DOI: 10.1073/Pnas.0503677102 |
0.39 |
|
2005 |
Hwang HC, Clurman BE. Cyclin E in normal and neoplastic cell cycles. Oncogene. 24: 2776-86. PMID 15838514 DOI: 10.1038/Sj.Onc.1208613 |
0.387 |
|
2005 |
Welcker M, Clurman BE. The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4. The Journal of Biological Chemistry. 280: 7654-8. PMID 15611062 DOI: 10.1074/Jbc.M413377200 |
0.497 |
|
2004 |
Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, Diyagama D, Grim JE, Clurman BE, Bowtell DD, Lee JS, et al. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. The Journal of Cell Biology. 167: 925-34. PMID 15583032 DOI: 10.1083/Jcb.200409187 |
0.402 |
|
2004 |
Chen X, Chi Y, Bloecher A, Aebersold R, Clurman BE, Roberts JM. N-acetylation and ubiquitin-independent proteasomal degradation of p21(Cip1). Molecular Cell. 16: 839-47. PMID 15574338 DOI: 10.1016/J.Molcel.2004.11.011 |
0.346 |
|
2004 |
Welcker M, Orian A, Grim JE, Grim JA, Eisenman RN, Clurman BE. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Current Biology : Cb. 14: 1852-7. PMID 15498494 DOI: 10.1016/J.Cub.2004.09.083 |
0.417 |
|
2004 |
Noseda M, Chang L, McLean G, Grim JE, Clurman BE, Smith LL, Karsan A. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Molecular and Cellular Biology. 24: 8813-22. PMID 15456857 DOI: 10.1128/Mcb.24.20.8813-8822.2004 |
0.367 |
|
2004 |
Ye X, Nalepa G, Welcker M, Kessler BM, Spooner E, Qin J, Elledge SJ, Clurman BE, Harper JW. Recognition of phosphodegron motifs in human cyclin E by the SCF Fbw7 ubiquitin ligase Journal of Biological Chemistry. 279: 50110-50119. PMID 15364936 DOI: 10.1074/Jbc.M409226200 |
0.435 |
|
2004 |
Welcker M, Orian A, Jin J, Grim JE, Grim JA, Harper JW, Eisenman RN, Clurman BE. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proceedings of the National Academy of Sciences of the United States of America. 101: 9085-90. PMID 15150404 DOI: 10.1073/Pnas.0402770101 |
0.412 |
|
2003 |
Welcker M, Singer J, Loeb KR, Grim J, Bloecher A, Gurien-West M, Clurman BE, Roberts JM. Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation. Molecular Cell. 12: 381-92. PMID 14536078 DOI: 10.1016/S1097-2765(03)00287-9 |
0.437 |
|
2003 |
Grim JE, Clurman BE. Cycling without CDK2? Trends in Cell Biology. 13: 396-9. PMID 12888290 DOI: 10.1016/S0962-8924(03)00148-X |
0.419 |
|
2003 |
Grandori C, Wu KJ, Fernandez P, Ngouenet C, Grim J, Clurman BE, Moser MJ, Oshima J, Russell DW, Swisshelm K, Frank S, Amati B, Dalla-Favera R, Monnat RJ. Werner syndrome protein limits MYC-induced cellular senescence Genes and Development. 17: 1569-1574. PMID 12842909 DOI: 10.1101/Gad.1100303 |
0.396 |
|
2002 |
Minella AC, Swanger J, Bryant E, Welcker M, Hwang H, Clurman BE. p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation. Current Biology : Cb. 12: 1817-27. PMID 12419181 DOI: 10.1016/S0960-9822(02)01225-3 |
0.423 |
|
2002 |
Hwang HC, Martins CP, Bronkhorst Y, Randel E, Berns A, Fero M, Clurman BE. Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis Proceedings of the National Academy of Sciences of the United States of America. 99: 11293-11298. PMID 12151601 DOI: 10.1073/Pnas.162356099 |
0.371 |
|
2000 |
Smitherman M, Lee K, Swanger J, Kapur R, Clurman BE. Characterization and targeted disruption of murine Nup50, a p27(Kip1)-interacting component of the nuclear pore complex. Molecular and Cellular Biology. 20: 5631-42. PMID 10891500 DOI: 10.1128/Mcb.20.15.5631-5642.2000 |
0.447 |
|
2000 |
Guan T, Kehlenbach RH, Schirmer EC, Kehlenbach A, Fan F, Clurman BE, Arnheim N, Gerace L. Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export. Molecular and Cellular Biology. 20: 5619-30. PMID 10891499 DOI: 10.1128/Mcb.20.15.5619-5630.2000 |
0.341 |
|
2000 |
Sheaff RJ, Singer JD, Swanger J, Smitherman M, Roberts JM, Clurman BE. Proteasomal turnover of p21(Cip1) does not require p21(Cip1) ubiquitination Molecular Cell. 5: 403-410. PMID 10882081 DOI: 10.1016/S1097-2765(00)80435-9 |
0.368 |
|
1999 |
Singer JD, Gurian-West M, Clurman B, Roberts JM. Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. Genes & Development. 13: 2375-87. PMID 10500095 DOI: 10.1101/Gad.13.18.2375 |
0.458 |
|
1999 |
Stirewalt DL, Clurman B, Appelbaum FR, Willman CL, Radich JP. p73 mutations and expression in adult de novo acute myelogenous leukemia. Leukemia. 13: 985-90. PMID 10400412 DOI: 10.1038/Sj.Leu.2401418 |
0.302 |
|
1998 |
Clurman BE, Porter P. New insights into the tumor suppression function of p27(kip1) Proceedings of the National Academy of Sciences of the United States of America. 95: 15158-15160. PMID 9860936 DOI: 10.1073/Pnas.95.26.15158 |
0.318 |
|
1998 |
Levkau B, Koyama H, Raines EW, Clurman BE, Herren B, Orth K, Roberts JM, Ross R. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of cdk2: Role of a caspase cascade Molecular Cell. 1: 553-563. PMID 9660939 DOI: 10.1016/S1097-2765(00)80055-6 |
0.346 |
|
1998 |
Clurman BE, Groudine M. The CDKN2A tumor-suppressor logus - A tale of two proteins New England Journal of Medicine. 338: 910-912. PMID 9516230 DOI: 10.1056/Nejm199803263381312 |
0.314 |
|
1997 |
Clurman B, Groudine M. Tumour-suppressor genes. Killer in search of a motive? Nature. 389: 122-3. PMID 9296483 DOI: 10.1038/38116 |
0.363 |
|
1997 |
Sheaff RJ, Groudine M, Gordon M, Roberts JM, Clurman BE. Cyclin E-CDK2 is a regulator of p27(Kip1) Genes and Development. 11: 1464-1478. PMID 9192873 DOI: 10.1101/Gad.11.11.1464 |
0.434 |
|
1997 |
Clurman B, Groudine M. Defining tumour-suppressor genes Nature. 389: 123-123. DOI: 10.1038/38119 |
0.32 |
|
1996 |
Clurman BE, Roberts JM, Groudine M. Deregulation of cell cycle control in hematologic malignancies Current Opinion in Hematology. 3: 315-320. PMID 9372094 DOI: 10.1097/00062752-199603040-00011 |
0.383 |
|
1996 |
Clurman BE, Sheaff RJ, Thress K, Groudine M, Roberts JM. Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation Genes and Development. 10: 1979-1990. PMID 8769642 DOI: 10.1101/Gad.10.16.1979 |
0.418 |
|
1995 |
Clurman BE, Roberts JM. Cell cycle and cancer Journal of the National Cancer Institute. 87: 1499-1501. PMID 7563177 DOI: 10.1093/Jnci/87.20.1499 |
0.465 |
|
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