Winfried Edelmann - Publications

Yeshiva University, New York, NY, United States 
Genetics, Cell Biology, Molecular Biology, Oncology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Milano CR, Holloway JK, Zhang Y, Jin B, Smith C, Bergman A, Edelmann W, Cohen PE. Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis. G3 (Bethesda, Md.). PMID 30944090 DOI: 10.1534/g3.119.400074  0.48
2018 Zhao X, Zhang Y, Wilkins K, Edelmann W, Usdin K. MutLγ promotes repeat expansion in a Fragile X mouse model while EXO1 is protective. Plos Genetics. 14: e1007719. PMID 30312299 DOI: 10.1371/journal.pgen.1007719  0.48
2017 Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM. Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair. Oncotarget. 8: 71574-71586. PMID 29069730 DOI: 10.18632/oncotarget.17776  0.48
2017 Chen CC, Avdievich E, Zhang Y, Zhang Y, Wei K, Lee K, Edelmann W, Jasin M, LaRocque JR. EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells. Dna Repair. 57: 98-106. PMID 28711786 DOI: 10.1016/j.dnarep.2017.07.003  0.52
2017 Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM. Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair. Oncotarget. PMID 28548965 DOI: 10.18632/oncotarget.17776  0.48
2016 Zhang Y, Fox JT, Park YU, Elliott G, Rai G, Cai M, Sakamuru S, Huang R, Xia M, Lee K, Jeon MH, Mathew BP, Park HD, Edelmann W, Park CY, et al. A novel chemotherapeutic agent to treat tumors with DNA mismatch repair deficiencies. Cancer Research. PMID 27262172 DOI: 10.1158/0008-5472.CAN-15-2974  0.36
2016 Eso Y, Takai A, Matsumoto T, Inuzuka T, Horie T, Ono K, Uemoto S, Lee K, Edelmann W, Chiba T, Marusawa H. MSH2 dysregulation is triggered by proinflammatory cytokine stimulation and is associated with liver cancer development. Cancer Research. PMID 27261510 DOI: 10.1158/0008-5472.CAN-15-2926  0.48
2016 He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, et al. Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development (Cambridge, England). 143: 1937-47. PMID 27246713 DOI: 10.1242/dev.135285  0.4
2016 Borras E, San Lucas FA, Chang K, Zhou R, Masand G, Fowler J, Mork ME, You YN, Taggart MW, McAllister F, Jones DA, Davies GE, Edelmann W, Ehli EA, Lynch PM, et al. Genomic Landscape of Colorectal Mucosa and Adenomas. Cancer Prevention Research (Philadelphia, Pa.). PMID 27221540 DOI: 10.1158/1940-6207.CAPR-16-0081  0.4
2015 Lee K, Tosti E, Edelmann W. Mouse models of DNA mismatch repair in cancer research. Dna Repair. PMID 26708047 DOI: 10.1016/j.dnarep.2015.11.015  0.4
2015 Rein K, Yanez DA, Terré B, Palenzuela L, Aivio S, Wei K, Edelmann W, Stark JM, Stracker TH. EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele. Nucleic Acids Research. PMID 26160886 DOI: 10.1093/nar/gkv691  0.4
2015 Chen HJ, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, Joe DJ, Choi J, Gadamsetty P, Milsom J, Nandakumar G, Longman R, Zhou XK, Edwards R, Chen J, ... ... Edelmann W, et al. Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. Nature Biotechnology. 33: 656-60. PMID 26006007 DOI: 10.1038/nbt.3239  0.4
2014 Tosti E, Katakowski JA, Schaetzlein S, Kim HS, Ryan CJ, Shales M, Roguev A, Krogan NJ, Palliser D, Keogh MC, Edelmann W. Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells. Genome Medicine. 6: 68. PMID 25302077 DOI: 10.1186/s13073-014-0068-4  0.4
2014 Woerner SM, Tosti E, Yuan YP, Kloor M, Bork P, Edelmann W, Gebert J. Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors. Molecular Carcinogenesis. PMID 25213383 DOI: 10.1002/mc.22213  0.4
2014 Belcheva A, Irrazabal T, Robertson SJ, Streutker C, Maughan H, Rubino S, Moriyama EH, Copeland JK, Kumar S, Green B, Geddes K, Pezo RC, Navarre WW, Milosevic M, Wilson BC, ... ... Edelmann W, et al. Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells. Cell. 158: 288-99. PMID 25036629 DOI: 10.1016/j.cell.2014.04.051  0.4
2014 Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, ... ... Edelmann W, et al. Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function. Cell Reports. 6: 892-905. PMID 24565511 DOI: 10.1016/j.celrep.2014.01.029  0.4
2014 Zhang Y, Werling U, Edelmann W. Seamless Ligation Cloning Extract (SLiCE) cloning method. Methods in Molecular Biology (Clifton, N.J.). 1116: 235-44. PMID 24395368 DOI: 10.1007/978-1-62703-764-8_16  0.48
2014 van Oers JM, Edwards Y, Chahwan R, Zhang W, Smith C, Pechuan X, Schaetzlein S, Jin B, Wang Y, Bergman A, Scharff MD, Edelmann W. The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair. Oncogene. 33: 3939-46. PMID 24013230 DOI: 10.1038/onc.2013.365  0.4
2013 Schaetzlein S, Chahwan R, Avdievich E, Roa S, Wei K, Eoff RL, Sellers RS, Clark AB, Kunkel TA, Scharff MD, Edelmann W. Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes. Proceedings of the National Academy of Sciences of the United States of America. 110: E2470-9. PMID 23754438 DOI: 10.1073/pnas.1308512110  0.4
2013 Ene AC, Park S, Edelmann W, Taketo T. Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Developmental Biology. 377: 213-23. PMID 23384561 DOI: 10.1016/j.ydbio.2013.01.027  0.44
2013 Bothmer A, Rommel PC, Gazumyan A, Polato F, Reczek CR, Muellenbeck MF, Schaetzlein S, Edelmann W, Chen PL, Brosh RM, Casellas R, Ludwig T, Baer R, Nussenzweig A, Nussenzweig MC, et al. Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching. The Journal of Experimental Medicine. 210: 115-23. PMID 23254285 DOI: 10.1084/jem.20121975  0.4
2012 Chahwan R, Edelmann W, Scharff MD, Roa S. AIDing antibody diversity by error-prone mismatch repair. Seminars in Immunology. 24: 293-300. PMID 22703640 DOI: 10.1016/j.smim.2012.05.005  0.4
2012 Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, ... Edelmann W, et al. Hierarchical modularity and the evolution of genetic interactomes across species. Molecular Cell. 46: 691-704. PMID 22681890 DOI: 10.1016/j.molcel.2012.05.028  0.4
2012 Chahwan R, van Oers JM, Avdievich E, Zhao C, Edelmann W, Scharff MD, Roa S. The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination. The Journal of Experimental Medicine. 209: 671-8. PMID 22451719 DOI: 10.1084/jem.20111531  0.4
2012 Zhang Y, Werling U, Edelmann W. SLiCE: a novel bacterial cell extract-based DNA cloning method. Nucleic Acids Research. 40: e55. PMID 22241772 DOI: 10.1093/nar/gkr1288  0.48
2011 Chahwan R, Edelmann W, Scharff MD, Roa S. Mismatch-mediated error prone repair at the immunoglobulin genes. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 65: 529-36. PMID 22100214 DOI: 10.1016/j.biopha.2011.09.001  0.4
2011 McIlhatton MA, Tyler J, Kerepesi LA, Bocker-Edmonston T, Kucherlapati MH, Edelmann W, Kucherlapati R, Kopelovich L, Fishel R. Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model. Cancer Prevention Research (Philadelphia, Pa.). 4: 684-93. PMID 21436383 DOI: 10.1158/1940-6207.CAPR-10-0319  0.4
2010 Peled JU, Sellers RS, Iglesias-Ussel MD, Shin DM, Montagna C, Zhao C, Li Z, Edelmann W, Morse HC, Scharff MD. Msh6 protects mature B cells from lymphoma by preserving genomic stability. The American Journal of Pathology. 177: 2597-608. PMID 20934970 DOI: 10.2353/ajpath.2010.100234  0.4
2010 Reiss C, Haneke T, Völker HU, Spahn M, Rosenwald A, Edelmann W, Kneitz B. Conditional inactivation of MLH1 in thymic and naive T-cells in mice leads to a limited incidence of lymphoblastic T-cell lymphomas. Leukemia & Lymphoma. 51: 1875-86. PMID 20858091 DOI: 10.3109/10428194.2010.510360  0.4
2010 Wang Y, Huang B, Edelmann L, Kolodner RD, Edelmann W. Genes essential for cell viability that are linked to tumor suppressor genes play a role in cancer susceptibility Cell Cycle. 9: 3144-3145. PMID 20703099 DOI: 10.4161/cc.9.16.12956  0.4
2010 van Oers JM, Roa S, Werling U, Liu Y, Genschel J, Hou H, Sellers RS, Modrich P, Scharff MD, Edelmann W. PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance. Proceedings of the National Academy of Sciences of the United States of America. 107: 13384-9. PMID 20624957 DOI: 10.1073/pnas.1008589107  0.4
2010 Roa S, Li Z, Peled JU, Zhao C, Edelmann W, Scharff MD. MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites. Plos One. 5: e11182. PMID 20567595 DOI: 10.1371/journal.pone.0011182  0.4
2010 Wang Y, Zhang W, Edelmann L, Kolodner RD, Kucherlapati R, Edelmann W. Cis lethal genetic interactions attenuate and alter p53 tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 5511-5. PMID 20212136 DOI: 10.1073/pnas.1001223107  0.4
2010 Kucherlapati MH, Lee K, Nguyen AA, Clark AB, Hou H, Rosulek A, Li H, Yang K, Fan K, Lipkin M, Bronson RT, Jelicks L, Kunkel TA, Kucherlapati R, Edelmann W. An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents. Gastroenterology. 138: 993-1002.e1. PMID 19931261 DOI: 10.1053/j.gastro.2009.11.009  0.4
2009 Itano O, Yang K, Fan K, Kurihara N, Shinozaki H, Abe S, Jin B, Gravaghi C, Edelmann W, Augenlicht L, Kopelovich L, Kucherlapati R, Lamprecht S, Lipkin M. Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations. Carcinogenesis. 30: 1923-6. PMID 19755659 DOI: 10.1093/carcin/bgp200  0.4
2009 Tomé S, Holt I, Edelmann W, Morris GE, Munnich A, Pearson CE, Gourdon G. MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice. Plos Genetics. 5: e1000482. PMID 19436705 DOI: 10.1371/journal.pgen.1000482  0.4
2009 Kadyrov FA, Genschel J, Fang Y, Penland E, Edelmann W, Modrich P. A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair. Proceedings of the National Academy of Sciences of the United States of America. 106: 8495-500. PMID 19420220 DOI: 10.1073/pnas.0903654106  0.4
2009 Bolderson E, Richard DJ, Edelmann W, Khanna KK. Involvement of Exo1b in DNA damage-induced apoptosis. Nucleic Acids Research. 37: 3452-63. PMID 19339515 DOI: 10.1093/nar/gkp194  0.4
2009 Klapacz J, Meira LB, Luchetti DG, Calvo JA, Bronson RT, Edelmann W, Samson LD. O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 576-81. PMID 19124772 DOI: 10.1073/pnas.0811991106  0.4
2009 Dragileva E, Hendricks A, Teed A, Gillis T, Lopez ET, Friedberg EC, Kucherlapati R, Edelmann W, Lunetta KL, MacDonald ME, Wheeler VC. Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes. Neurobiology of Disease. 33: 37-47. PMID 18930147 DOI: 10.1016/j.nbd.2008.09.014  0.4
2008 Roa S, Avdievich E, Peled JU, Maccarthy T, Werling U, Kuang FL, Kan R, Zhao C, Bergman A, Cohen PE, Edelmann W, Scharff MD. Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression. Proceedings of the National Academy of Sciences of the United States of America. 105: 16248-53. PMID 18854411 DOI: 10.1073/pnas.0808182105  0.4
2008 Yang K, Kurihara N, Fan K, Newmark H, Rigas B, Bancroft L, Corner G, Livote E, Lesser M, Edelmann W, Velcich A, Lipkin M, Augenlicht L. Dietary induction of colonic tumors in a mouse model of sporadic colon cancer. Cancer Research. 68: 7803-10. PMID 18829535 DOI: 10.1158/0008-5472.CAN-08-1209  0.4
2008 Yang K, Popova NV, Yang WC, Lozonschi I, Tadesse S, Kent S, Bancroft L, Matise I, Cormier RT, Scherer SJ, Edelmann W, Lipkin M, Augenlicht L, Velcich A. Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation. Cancer Research. 68: 7313-22. PMID 18794118 DOI: 10.1158/0008-5472.CAN-08-0598  0.4
2008 Marinovic-Terzic I, Yoshioka-Yamashita A, Shimodaira H, Avdievich E, Hunton IC, Kolodner RD, Edelmann W, Wang JYJ. Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q Proceedings of the National Academy of Sciences of the United States of America. 105: 13993-13998. PMID 18768816 DOI: 10.1073/pnas.0806435105  0.4
2008 Yang K, Lamprecht SA, Shinozaki H, Fan K, Yang W, Newmark HL, Kopelovich L, Edelmann W, Jin B, Gravaghi C, Augenlicht L, Kucherlapati R, Lipkin M. Dietary calcium and cholecalciferol modulate cyclin D1 expression, apoptosis, and tumorigenesis in intestine of adenomatous polyposis coli1638N/+ mice. The Journal of Nutrition. 138: 1658-63. PMID 18716166  0.4
2008 Chen PC, Kuraguchi M, Velasquez J, Wang Y, Yang K, Edwards R, Gillen D, Edelmann W, Kucherlapati R, Lipkin SM. Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression. Plos Genetics. 4: e1000092. PMID 18551179 DOI: 10.1371/journal.pgen.1000092  0.4
2008 Avdievich E, Reiss C, Scherer SJ, Zhang Y, Maier SM, Jin B, Hou H, Rosenwald A, Riedmiller H, Kucherlapati R, Cohen PE, Edelmann W, Kneitz B. Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4247-52. PMID 18337503 DOI: 10.1073/pnas.0800276105  0.4
2008 Kan R, Sun X, Kolas NK, Avdievich E, Kneitz B, Edelmann W, Cohen PE. Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway. Biology of Reproduction. 78: 462-71. PMID 18057311 DOI: 10.1095/biolreprod.107.065771  0.52
2007 Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepczynska A, Lilli DR, Clark AB, Rudolph C, Kuhnel F, Wei K, Schlegelberger B, Schirmacher P, Kunkel TA, Greenberg RA, Edelmann W, et al. Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice. Cell. 130: 863-77. PMID 17803909 DOI: 10.1016/j.cell.2007.08.029  0.4
2006 Hegan DC, Narayanan L, Jirik FR, Edelmann W, Liskay RM, Glazer PM. Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6. Carcinogenesis. 27: 2402-8. PMID 16728433 DOI: 10.1093/carcin/bgl079  0.4
2006 Li Z, Zhao C, Iglesias-Ussel MD, Polonskaya Z, Zhuang M, Yang G, Luo Z, Edelmann W, Scharff MD. The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus. Immunity. 24: 393-403. PMID 16618598 DOI: 10.1016/j.immuni.2006.02.011  0.4
2005 Zervas M, Opitz T, Edelmann W, Wainer B, Kucherlapati R, Stanton PK. Impaired hippocampal long-term potentiation in microtubule-associated protein 1B-deficient mice. Journal of Neuroscience Research. 82: 83-92. PMID 16118800 DOI: 10.1002/jnr.20624  0.4
2005 Scherer SJ, Avdievich E, Edelmann W. Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition. Biochemical Society Transactions. 33: 689-93. PMID 16042575 DOI: 10.1042/BST0330689  0.52
2005 Owen BA, Yang Z, Lai M, Gajec M, Gajek M, Badger JD, Hayes JJ, Edelmann W, Kucherlapati R, Wilson TM, McMurray CT. (CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition. Nature Structural & Molecular Biology. 12: 663-70. PMID 16025128 DOI: 10.1038/nsmb965  0.4
2005 Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, Edelmann W. Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice. Nature Genetics. 37: 750-5. PMID 15965476 DOI: 10.1038/ng1587  0.4
2005 Yang K, Fan KH, Lamprecht SA, Edelmann W, Kopelovich L, Kucherlapati R, Lipkin M. Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice. International Journal of Cancer. Journal International Du Cancer. 116: 495-9. PMID 15818612 DOI: 10.1002/ijc.21018  0.4
2005 Di Giacomo M, Barchi M, Baudat F, Edelmann W, Keeney S, Jasin M. Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. Proceedings of the National Academy of Sciences of the United States of America. 102: 737-42. PMID 15640358 DOI: 10.1073/pnas.0406212102  0.48
2004 Yang G, Scherer SJ, Shell SS, Yang K, Kim M, Lipkin M, Kucherlapati R, Kolodner RD, Edelmann W. Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. Cancer Cell. 6: 139-50. PMID 15324697 DOI: 10.1016/j.ccr.2004.06.024  0.4
2004 Li Z, Scherer SJ, Ronai D, Iglesias-Ussel MD, Peled JU, Bardwell PD, Zhuang M, Lee K, Martin A, Edelmann W, Scharff MD. Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification. The Journal of Experimental Medicine. 200: 47-59. PMID 15238604 DOI: 10.1084/jem.20040355  0.4
2004 Lin DP, Wang Y, Scherer SJ, Clark AB, Yang K, Avdievich E, Jin B, Werling U, Parris T, Kurihara N, Umar A, Kucherlapati R, Lipkin M, Kunkel TA, Edelmann W. An Msh2 point mutation uncouples DNA mismatch repair and apoptosis. Cancer Research. 64: 517-22. PMID 14744764 DOI: 10.1158/0008-5472.CAN-03-2957  0.4
2004 Bardwell PD, Woo CJ, Wei K, Li Z, Martin A, Sack SZ, Parris T, Edelmann W, Scharff MD. Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. Nature Immunology. 5: 224-9. PMID 14716311 DOI: 10.1038/ni1031  0.4
2003 Kabbarah O, Mallon MA, Pfeifer JD, Edelmann W, Kucherlapati R, Goodfellow PJ. A panel of repeat markers for detection of microsatellite instability in murine tumors. Molecular Carcinogenesis. 38: 155-9. PMID 14639654 DOI: 10.1002/mc.10157  0.4
2003 Young LC, Peters AC, Maeda T, Edelmann W, Kucherlapati R, Andrew SE, Tron VA. DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts. The Journal of Investigative Dermatology. 121: 876-80. PMID 14632208 DOI: 10.1046/j.1523-1747.2003.12486.x  0.4
2003 Pretlow TP, Edelmann W, Kucherlapati R, Pretlow TG, Augenlicht LH. Spontaneous aberrant crypt foci in Apc1638N mice with a mutant Apc allele. The American Journal of Pathology. 163: 1757-63. PMID 14578176 DOI: 10.1016/S0002-9440(10)63535-3  0.4
2003 Martin A, Li Z, Lin DP, Bardwell PD, Iglesias-Ussel MD, Edelmann W, Scharff MD. Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination. The Journal of Experimental Medicine. 198: 1171-8. PMID 14568978 DOI: 10.1084/jem.20030880  0.4
2003 Shinozaki H, Yang K, Fan K, Edelmann W, Kucherlapati R, Weinstein IB, Lipkin M. Cyclin D1 expression in the intestinal mucosa and tumors of Apc1638N mice. Anticancer Research. 23: 2217-26. PMID 12894495  0.4
2003 Yang K, Fan K, Kurihara N, Shinozaki H, Rigas B, Augenlicht L, Kopelovich L, Edelmann W, Kucherlapati R, Lipkin M. Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations. Carcinogenesis. 24: 605-11. PMID 12663524 DOI: 10.1093/carcin/24.3.605  0.4
2003 Wei K, Clark AB, Wong E, Kane MF, Mazur DJ, Parris T, Kolas NK, Russell R, Hou H, Kneitz B, Yang G, Kunkel TA, Kolodner RD, Cohen PE, Edelmann W. Inactivation of exonuclease I in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility Genes and Development. 17: 603-614. PMID 12629043 DOI: 10.1101/gad.1060603  0.4
2003 Bardwell PD, Martin A, Wong E, Li Z, Edelmann W, Scharff MD. Cutting edge: the G-U mismatch glycosylase methyl-CpG binding domain 4 is dispensable for somatic hypermutation and class switch recombination. Journal of Immunology (Baltimore, Md. : 1950). 170: 1620-4. PMID 12574322  0.4
2002 Wong E, Yang K, Kuraguchi M, Werling U, Avdievich E, Fan K, Fazzari M, Jin B, Brown AM, Lipkin M, Edelmann W. Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 14937-42. PMID 12417741 DOI: 10.1073/pnas.232579299  0.52
2002 Mark SC, Sandercock LE, Luchman HA, Baross A, Edelmann W, Jirik FR. Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium. Oncogene. 21: 7126-30. PMID 12370835 DOI: 10.1038/sj.onc.1205861  0.4
2002 Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, Kucherlapati R, Gonzalez FJ, Spiegelman BM. APC-dependent suppression of colon carcinogenesis by PPARgamma. Proceedings of the National Academy of Sciences of the United States of America. 99: 13771-6. PMID 12370429 DOI: 10.1073/pnas.162480299  0.4
2002 Kucherlapati M, Yang K, Kuraguchi M, Zhao J, Lia M, Heyer J, Kane MF, Fan K, Russell R, Brown AM, Kneitz B, Edelmann W, Kolodner RD, Lipkin M, Kucherlapati R. Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 99: 9924-9. PMID 12119409 DOI: 10.1073/pnas.152321699  0.4
2002 Wei K, Kucherlapati R, Edelmann W. Mouse models for human DNA mismatch-repair gene defects. Trends in Molecular Medicine. 8: 346-53. PMID 12114115 DOI: 10.1016/S1471-4914(02)02359-6  0.4
2002 Wang H, Douglas W, Lia M, Edelmann W, Kucherlapati R, Podsypanina K, Parsons R, Ellenson LH. DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice. The American Journal of Pathology. 160: 1481-6. PMID 11943731 DOI: 10.1016/S0002-9440(10)62573-4  0.4
2002 Razani B, Wang XB, Engelman JA, Battista M, Lagaud G, Zhang XL, Kneitz B, Hou H, Christ GJ, Edelmann W, Lisanti MP. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Molecular and Cellular Biology. 22: 2329-44. PMID 11884617 DOI: 10.1128/MCB.22.7.2329-2344.2002  0.4
2001 Kuraguchi M, Yang K, Wong E, Avdievich E, Fan K, Kolodner RD, Lipkin M, Brown AM, Kucherlapati R, Edelmann W. The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Research. 61: 7934-42. PMID 11691815  0.4
2000 Kneitz B, Cohen PE, Avdievich E, Zhu L, Kane MF, Hou H, Kolodner RD, Kucherlapati R, Pollard JW, Edelmann W. MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes & Development. 14: 1085-97. PMID 10809667  0.4
2000 Edelmann W, Umar A, Yang K, Heyer J, Kucherlapati M, Lia M, Kneitz B, Avdievich E, Fan K, Wong E, Crouse G, Kunkel T, Lipkin M, Kolodner RD, Kucherlapati R. The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Research. 60: 803-7. PMID 10706084  0.4
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