Thomas J. Begley - Publications

Affiliations: 
Biomedical Sciences State University of New York, Albany, Albany, NY, United States 
Area:
Molecular Biology, Cell Biology, Genetics, Oncology

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mitchener MM, Begley TJ, Dedon PC. Molecular Coping Mechanisms: Reprogramming tRNAs To Regulate Codon-Biased Translation of Stress Response Proteins. Accounts of Chemical Research. 56: 3504-3514. PMID 37992267 DOI: 10.1021/acs.accounts.3c00572  0.387
2022 Dedon PC, Begley TJ. Dysfunctional tRNA reprogramming and codon-biased translation in cancer. Trends in Molecular Medicine. 28: 964-978. PMID 36241532 DOI: 10.1016/j.molmed.2022.09.007  0.335
2022 Huber SM, Begley U, Sarkar A, Gasperi W, Davis ET, Surampudi V, Lee M, Melendez JA, Dedon PC, Begley TJ. Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123529119. PMID 36095201 DOI: 10.1073/pnas.2123529119  0.363
2022 Evke S, Lin Q, Melendez JA, Begley TJ. Epitranscriptomic Reprogramming Is Required to Prevent Stress and Damage from Acetaminophen. Genes. 13. PMID 35327975 DOI: 10.3390/genes13030421  0.337
2020 St John N, Freedland J, Baldino H, Doyle F, Cera C, Begley T, Fasullo M. Genome Profiling for Aflatoxin B Resistance in Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B-Associated DNA Damage. G3 (Bethesda, Md.). PMID 32994210 DOI: 10.1534/g3.120.401723  0.35
2020 Leonardi A, Kovalchuk N, Yin L, Endres L, Evke S, Nevins S, Martin S, Dedon PC, Melendez JA, Van Winkle L, Zhang QY, Ding X, Begley TJ. The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene. Epigenetics. 1-18. PMID 32303148 DOI: 10.1080/15592294.2020.1750213  0.345
2020 Pollo-Oliveira L, Klassen R, Davis N, Ciftci A, Bacusmo JM, Martinelli M, DeMott MS, Begley TJ, Dedon PC, Schaffrath R, de Crécy-Lagard V. Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast. Biomolecules. 10. PMID 32085421 DOI: 10.3390/biom10020322  0.331
2019 Lee MY, Leonardi A, Begley TJ, Melendez JA. Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming. Redox Biology. 28: 101375. PMID 31765888 DOI: 10.1016/J.Redox.2019.101375  0.428
2019 Leonardi A, Evke S, Lee M, Melendez JA, Begley TJ. Epitranscriptomic systems regulate the translation of reactive oxygen species detoxifying and disease linked selenoproteins. Free Radical Biology & Medicine. PMID 31476365 DOI: 10.1016/J.Freeradbiomed.2019.08.030  0.428
2019 Huber SM, Leonardi A, Dedon PC, Begley TJ. The Versatile Roles of the tRNA Epitranscriptome during Cellular Responses to Toxic Exposures and Environmental Stress. Toxics. 7. PMID 30934574 DOI: 10.3390/Toxics7010017  0.464
2018 Chan C, Pham P, Dedon PC, Begley TJ. Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses. Genome Biology. 19: 228. PMID 30587213 DOI: 10.1186/S13059-018-1611-1  0.4
2018 Rothenberg DA, Taliaferro JM, Huber SM, Begley TJ, Dedon PC, White FM. A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth. Iscience. 9: 367-381. PMID 30466063 DOI: 10.1016/J.Isci.2018.11.004  0.404
2018 Gu C, Ramos J, Begley U, Dedon PC, Fu D, Begley TJ. Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression. Science Advances. 4: eaas9184. PMID 30009260 DOI: 10.1126/Sciadv.Aas9184  0.331
2018 Lee M, Leonardi A, Evke S, Criscione C, Begley T, Melendez A. Selenoprotein loss resulting from Alkbh8 deficiency engages senescence and metabolic programming and predicts poor clear cell renal cancer cell survival Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.147  0.374
2017 Nagel ZD, Engelward BP, Brenner DJ, Begley TJ, Sobol RW, Bielas JH, Stambrook PJ, Wei Q, Hu JJ, Terry MB, Dilworth C, McAllister KA, Reinlib L, Worth L, Shaughnessy DT. Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease. Mutation Research. 800: 14-28. PMID 28458064 DOI: 10.1016/J.Mrfmmm.2017.03.007  0.333
2017 Idelchik MDPS, Begley U, Begley TJ, Melendez JA. Mitochondrial ROS Control of Cancer. Seminars in Cancer Biology. PMID 28445781 DOI: 10.1016/J.Semcancer.2017.04.005  0.343
2017 Hseih Y, Begley U, Endres L, Keith J, Hansen AF, Kaminsky L, McCandless B, Begley TJ. Activation of DNA Damage Signaling Components by Diagnostic Computed Tomography (CT) Scans Detected in Patient Samples Using an Electrochemiluminescence-Based Assay Platform Advances in Bioscience and Biotechnology. 8: 228-247. DOI: 10.4236/Abb.2017.87017  0.351
2017 Lee MY, Leonardi A, Shapiro R, Boivin BA, Begley TJ, Melendez JA. Loss of Epitranscriptomic Control of Seleno-cysteine Utilization Engages Senescence and Metabolic Reprogramming through mTOR Activation and Predicts Poor Survival in Clear Cell Renal Cell Cancer Patients Free Radical Biology and Medicine. 112: 94. DOI: 10.1016/J.Freeradbiomed.2017.10.139  0.36
2016 Chionh YH, McBee M, Babu IR, Hia F, Lin W, Zhao W, Cao J, Dziergowska A, Malkiewicz A, Begley TJ, Alonso S, Dedon PC. tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence. Nature Communications. 7: 13302. PMID 27834374 DOI: 10.1038/Ncomms13302  0.446
2016 Doyle F, Leonardi A, Endres L, Tenenbaum SA, Dedon PC, Begley TJ. Gene- and Genome-Based Analysis of Significant Codon Patterns in Yeast, Rat and Mice Genomes with the CUT Codon Utilization Tool. Methods (San Diego, Calif.). PMID 27245397 DOI: 10.1016/J.Ymeth.2016.05.010  0.447
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Begley TJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.348
2016 Onanuga K, Begley U, Begley TJ. Understanding the Role of Selenium in Reactive Oxygen Species Management in Colorectal Cancers Free Radical Biology and Medicine. 100. DOI: 10.1016/J.Freeradbiomed.2016.10.333  0.372
2016 Lee M, Criscione C, Leonardi A, Chandrasekaran A, Begley TJ, Andres Melendez J. Epitranscriptomic Control of Selenoprotein Synthesis, Senescence, Mitochondrial Bioenergetics and Clear Cell Renal Cell Carcinoma Free Radical Biology and Medicine. 100: S124-S125. DOI: 10.1016/J.Freeradbiomed.2016.10.324  0.473
2015 Deng W, Babu IR, Su D, Yin S, Begley TJ, Dedon PC. Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation. Plos Genetics. 11: e1005706. PMID 26670883 DOI: 10.1371/Journal.Pgen.1005706  0.474
2015 Cai WM, Chionh YH, Hia F, Gu C, Kellner S, McBee ME, Ng CS, Pang YL, Prestwich EG, Lim KS, Ramesh Babu I, Begley TJ, Dedon PC. A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications. Methods in Enzymology. 560: 29-71. PMID 26253965 DOI: 10.1016/Bs.Mie.2015.03.004  0.341
2015 Endres L, Begley U, Clark R, Gu C, Dziergowska A, Ma?kiewicz A, Melendez JA, Dedon PC, Begley TJ. Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage. Plos One. 10: e0131335. PMID 26147969 DOI: 10.1371/Journal.Pone.0131335  0.498
2015 Endres L, Dedon PC, Begley TJ. Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses. Rna Biology. 12: 603-14. PMID 25892531 DOI: 10.1080/15476286.2015.1031947  0.477
2015 Chan CT, Deng W, Li F, DeMott MS, Babu IR, Begley TJ, Dedon PC. Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes. Chemical Research in Toxicology. 28: 978-88. PMID 25772370 DOI: 10.1021/Acs.Chemrestox.5B00004  0.469
2015 Gaupel AC, Begley TJ, Tenniswood M. Gcn5 Modulates the Cellular Response to Oxidative Stress and Histone Deacetylase Inhibition. Journal of Cellular Biochemistry. 116: 1982-92. PMID 25755069 DOI: 10.1002/Jcb.25153  0.384
2015 Kovvuru P, Mancilla PE, Shirode AB, Murray TM, Begley TJ, Reliene R. Oral ingestion of silver nanoparticles induces genomic instability and DNA damage in multiple tissues. Nanotoxicology. 9: 162-71. PMID 24713076 DOI: 10.3109/17435390.2014.902520  0.434
2015 Lee MY, Leonardi A, Chandrasekaran A, Begley TJ, Melendez JA. Alkbh8-Dependent Translational Control of Selenoprotein Synthesis and the Senescence Associated Secretory Phenotype (SASP) Free Radical Biology and Medicine. 87: S103. DOI: 10.1016/J.Freeradbiomed.2015.10.271  0.306
2014 Gu C, Begley TJ, Dedon PC. tRNA modifications regulate translation during cellular stress. Febs Letters. 588: 4287-96. PMID 25304425 DOI: 10.1016/J.Febslet.2014.09.038  0.439
2014 Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, et al. Mitochondria, energetics, epigenetics, and cellular responses to stress. Environmental Health Perspectives. 122: 1271-8. PMID 25127496 DOI: 10.1289/Ehp.1408418  0.412
2014 Gaupel AC, Begley T, Tenniswood M. High throughput screening identifies modulators of histone deacetylase inhibitors. Bmc Genomics. 15: 528. PMID 24968945 DOI: 10.1186/1471-2164-15-528  0.336
2014 Su D, Chan CT, Gu C, Lim KS, Chionh YH, McBee ME, Russell BS, Babu IR, Begley TJ, Dedon PC. Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry. Nature Protocols. 9: 828-41. PMID 24625781 DOI: 10.1038/Nprot.2014.047  0.339
2014 Dedon PC, Begley TJ. A system of RNA modifications and biased codon use controls cellular stress response at the level of translation. Chemical Research in Toxicology. 27: 330-7. PMID 24422464 DOI: 10.1021/Tx400438D  0.514
2014 Gaupel A, Begley TJ, Tenniswood MP. Abstract 5535: Gcn5 modulates the cellular response to oxidative stress induced by histone deacetylase inhibitors Cancer Research. 74: 5535-5535. DOI: 10.1158/1538-7445.Am2014-5535  0.388
2013 Lamichhane TN, Blewett NH, Crawford AK, Cherkasova VA, Iben JR, Begley TJ, Farabaugh PJ, Maraia RJ. Lack of tRNA modification isopentenyl-A37 alters mRNA decoding and causes metabolic deficiencies in fission yeast. Molecular and Cellular Biology. 33: 2918-29. PMID 23716598 DOI: 10.1128/Mcb.00278-13  0.402
2013 Begley U, Sosa MS, Avivar-Valderas A, Patil A, Endres L, Estrada Y, Chan CT, Su D, Dedon PC, Aguirre-Ghiso JA, Begley T. A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α. Embo Molecular Medicine. 5: 366-83. PMID 23381944 DOI: 10.1002/Emmm.201201161  0.662
2013 Gaupel A, Begley TJ, Tenniswood MP. Abstract 1002: Deletion of GCN5 confers sensitivity to the histone deacetylase inhibitor CG-1521. Cancer Research. 73: 1002-1002. DOI: 10.1158/1538-7445.Am2013-1002  0.366
2012 Svilar D, Dyavaiah M, Brown AR, Tang JB, Li J, McDonald PR, Shun TY, Braganza A, Wang XH, Maniar S, St Croix CM, Lazo JS, Pollack IF, Begley TJ, Sobol RW. Alkylation sensitivity screens reveal a conserved cross-species functionome. Molecular Cancer Research : McR. 10: 1580-96. PMID 23038810 DOI: 10.1158/1541-7786.Mcr-12-0168  0.457
2012 Patil A, Dyavaiah M, Joseph F, Rooney JP, Chan CT, Dedon PC, Begley TJ. Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response. Cell Cycle (Georgetown, Tex.). 11: 3656-65. PMID 22935709 DOI: 10.4161/Cc.21919  0.711
2012 Patil A, Chan CT, Dyavaiah M, Rooney JP, Dedon PC, Begley TJ. Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications. Rna Biology. 9: 990-1001. PMID 22832247 DOI: 10.4161/Rna.20531  0.702
2012 Chan CT, Pang YL, Deng W, Babu IR, Dyavaiah M, Begley TJ, Dedon PC. Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Nature Communications. 3: 937. PMID 22760636 DOI: 10.1038/Ncomms1938  0.422
2012 Tumu S, Patil A, Towns W, Dyavaiah M, Begley TJ. The gene-specific codon counting database: a genome-based catalog of one-, two-, three-, four- and five-codon combinations present in Saccharomyces cerevisiae genes. Database : the Journal of Biological Databases and Curation. 2012: bas002. PMID 22323063 DOI: 10.1093/Database/Bas002  0.655
2012 Towns WL, Begley TJ. Transfer RNA methytransferases and their corresponding modifications in budding yeast and humans: activities, predications, and potential roles in human health. Dna and Cell Biology. 31: 434-54. PMID 22191691 DOI: 10.1089/Dna.2011.1437  0.398
2011 Dyavaiah M, Rooney JP, Chittur SV, Lin Q, Begley TJ. Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1. Molecular Cancer Research : McR. 9: 462-75. PMID 21343333 DOI: 10.1158/1541-7786.Mcr-10-0473  0.525
2011 Rooney JP, Patil A, Joseph F, Endres L, Begley U, Zappala MR, Cunningham RP, Begley TJ. Cross-species Functionome analysis identifies proteins associated with DNA repair, translation and aerobic respiration as conserved modulators of UV-toxicity Genomics. 97: 133-147. PMID 21195161 DOI: 10.1016/J.Ygeno.2010.12.005  0.718
2010 Chan CT, Dyavaiah M, DeMott MS, Taghizadeh K, Dedon PC, Begley TJ. A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress. Plos Genetics. 6: e1001247. PMID 21187895 DOI: 10.1371/Journal.Pgen.1001247  0.413
2010 Sander M, Begley TJ, Desaintes C, Gavin AC, Pelroy R, Pothof J, Shiloh Y, van Gent D, Van Houten B, Yaffe M, Mullenders L. 3rd US-EU Workshop: Systems level understanding of DNA damage responses Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 692: 53-60. PMID 20727903 DOI: 10.1016/J.Mrfmmm.2010.07.012  0.391
2010 Fu D, Brophy JA, Chan CT, Atmore KA, Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD. Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival. Molecular and Cellular Biology. 30: 2449-59. PMID 20308323 DOI: 10.1128/Mcb.01604-09  0.507
2009 Arita A, Zhou X, Ellen TP, Liu X, Bai J, Rooney JP, Kurtz A, Klein CB, Dai W, Begley TJ, Costa M. A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae. Bmc Genomics. 10: 524. PMID 19917080 DOI: 10.1186/1471-2164-10-524  0.381
2009 Zhou X, Arita A, Ellen TP, Liu X, Bai J, Rooney JP, Kurtz AD, Klein CB, Dai W, Begley TJ, Costa M. A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity. Genomics. 94: 294-307. PMID 19631266 DOI: 10.1016/J.Ygeno.2009.07.003  0.425
2009 Rooney JP, George AD, Patil A, Begley U, Bessette E, Zappala MR, Huang X, Conklin DS, Cunningham RP, Begley TJ. Systems based mapping demonstrates that recovery from alkylation damage requires DNA repair, RNA processing, and translation associated networks. Genomics. 93: 42-51. PMID 18824089 DOI: 10.1016/J.Ygeno.2008.09.001  0.719
2008 Erlich RL, Fry RC, Begley TJ, Daee DL, Lahue RS, Samson LD. Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae. Plos One. 3: e3717. PMID 19005567 DOI: 10.1371/Journal.Pone.0003717  0.439
2008 Rooney JP, Patil A, Zappala MR, Conklin DS, Cunningham RP, Begley TJ. A molecular bar-coded DNA repair resource for pooled toxicogenomic screens Dna Repair. 7: 1855-1868. PMID 18723126 DOI: 10.1016/J.Dnarep.2008.07.013  0.703
2007 Begley U, Dyavaiah M, Patil A, Rooney JP, DiRenzo D, Young CM, Conklin DS, Zitomer RS, Begley TJ. Trm9-catalyzed tRNA modifications link translation to the DNA damage response. Molecular Cell. 28: 860-70. PMID 18082610 DOI: 10.1016/J.Molcel.2007.09.021  0.734
2007 Rusyn I, Fry RC, Begley TJ, Klapacz J, Svensson JP, Ambrose M, Samson LD. Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates. Plos One. 2: e1252. PMID 18043759 DOI: 10.1371/Journal.Pone.0001252  0.51
2006 Fry RC, DeMott MS, Cosgrove JP, Begley TJ, Samson LD, Dedon PC. The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA. Bmc Genomics. 7: 313. PMID 17163986 DOI: 10.1186/1471-2164-7-313  0.513
2006 Workman CT, Mak HC, McCuine S, Tagne JB, Agarwal M, Ozier O, Begley TJ, Samson LD, Ideker T. A systems approach to mapping DNA damage response pathways. Science (New York, N.Y.). 312: 1054-9. PMID 16709784 DOI: 10.1126/Science.1122088  0.46
2005 Fry RC, Begley TJ, Samson LD. Genome-wide responses to DNA-damaging agents. Annual Review of Microbiology. 59: 357-77. PMID 16153173 DOI: 10.1146/Annurev.Micro.59.031805.133658  0.49
2004 Said MR, Begley TJ, Oppenheim AV, Lauffenburger DA, Samson LD. Global network analysis of phenotypic effects: protein networks and toxicity modulation in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 101: 18006-11. PMID 15608068 DOI: 10.1073/Pnas.0405996101  0.436
2004 Begley TJ, Rosenbach AS, Ideker T, Samson LD. Hot spots for modulating toxicity identified by genomic phenotyping and localization mapping. Molecular Cell. 16: 117-25. PMID 15469827 DOI: 10.1016/J.Molcel.2004.09.005  0.432
2004 Begley TJ, Samson LD. Reversing DNA damage with a directional bias. Nature Structural & Molecular Biology. 11: 688-90. PMID 15280878 DOI: 10.1038/Nsmb0804-688  0.402
2004 Begley TJ, Samson LD. Network responses to DNA damaging agents. Dna Repair. 3: 1123-32. PMID 15279801 DOI: 10.1016/J.Dnarep.2004.03.013  0.471
2003 Begley TJ, Samson LD. Molecular biology: A fix for RNA. Nature. 421: 795-6. PMID 12594492 DOI: 10.1038/421795A  0.386
2003 Begley TJ, Samson LD. AlkB mystery solved: oxidative demethylation of N1-methyladenine and N3-methylcytosine adducts by a direct reversal mechanism. Trends in Biochemical Sciences. 28: 2-5. PMID 12517444 DOI: 10.1016/S0968-0004(02)00010-5  0.415
2003 Begley TJ, Haas BJ, Morales JC, Kool ET, Cunningham RP. Kinetics and binding of the thymine-DNA mismatch glycosylase, Mig-Mth, with mismatch-containing DNA substrates Dna Repair. 2: 107-120. PMID 12509271 DOI: 10.1016/S1568-7864(02)00190-8  0.379
2002 Begley TJ, Rosenbach AS, Ideker T, Samson LD. Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping Molecular Cancer Research. 1: 103-112. PMID 12496357  0.387
2002 Mol CD, Arvai AS, Begley TJ, Cunningham RP, Tainer JA. Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases. Journal of Molecular Biology. 315: 373-84. PMID 11786018 DOI: 10.1006/Jmbi.2001.5264  0.425
1999 Begley TJ, Haas BJ, Noel J, Shekhtman A, Williams WA, Cunningham RP. A new member of the endonuclease III family of DNA repair enzymes that removes methylated purines from DNA. Current Biology : Cb. 9: 653-6. PMID 10375529 DOI: 10.1016/S0960-9822(99)80288-7  0.441
1999 Begley TJ, Cunningham RP. Methanobacterium thermoformicicum thymine DNA mismatch glycosylase: Conversion of an n-glycosylase to an AP lyase Protein Engineering. 12: 333-340. PMID 10325404 DOI: 10.1093/Protein/12.4.333  0.362
1998 Fetrow JS, Spitzer JS, Gilden BM, Mellender SJ, Begley TJ, Haas BJ, Boose TL. Structure, function, and temperature sensitivity of directed, random mutants at proline 76 and glycine 77 in omega-loop D of yeast iso-1-cytochrome c. Biochemistry. 37: 2477-87. PMID 9485396 DOI: 10.1021/Bi972279A  0.348
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