Stephen Nimer - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Pharmacology, Oncology, Cell Biology

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ge G, Zhang P, Sui P, Chen S, Yang H, Guo Y, Rubalcava IP, Noor A, Delma CR, Agosto-Peña J, Geng H, Medina EA, Liang Y, Nimer SD, Mesa R, et al. Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in preclinical models. The Journal of Clinical Investigation. PMID 37917239 DOI: 10.1172/JCI163964  0.302
2023 Yang H, Sui P, Guo Y, Chen S, Maloof ME, Ge G, Nihozeko F, Delma CR, Zhu G, Zhang P, Ye Z, Medina EA, Ayad NG, Mesa R, Nimer SD, et al. Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping. Embo Reports. e57032. PMID 37650863 DOI: 10.15252/embr.202357032  0.304
2021 Man N, Mas G, Karl DL, Sun J, Liu F, Yang Q, Torres-Martin M, Itonaga H, Martinez C, Chen S, Xu Y, Duffort S, Hamard PJ, Chen C, Zucconi BE, ... ... Nimer SD, et al. p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia. Jci Insight. 6. PMID 34622806 DOI: 10.1172/jci.insight.138478  0.4
2021 Su H, Jiang M, Senevirathne C, Aluri S, Zhang T, Guo H, Xavier-Ferrucio J, Jin S, Tran NT, Liu SM, Sun CW, Zhu Y, Zhao Q, Chen Y, Cable L, ... ... Nimer SD, et al. Methylation of dual-specificity phosphatase 4 controls cell differentiation. Cell Reports. 36: 109421. PMID 34320342 DOI: 10.1016/j.celrep.2021.109421  0.358
2020 Wesely J, Kotini AG, Izzo F, Luo H, Yuan H, Sun J, Georgomanoli M, Zviran A, Deslauriers AG, Dusaj N, Nimer SD, Leslie C, Landau DA, Kharas MG, Papapetrou EP. Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells. Cell Reports. 31: 107688. PMID 32492433 DOI: 10.1016/J.Celrep.2020.107688  0.348
2020 Chen BY, Song J, Hu CL, Chen SB, Zhang Q, Xu CH, Wu JC, Hou D, Sun M, Zhang YL, Liu N, Yu PC, Liu P, Zong LJ, Zhang JY, ... ... Nimer SD, et al. SETD2 deficiency predicts poor prognosis in MDS and accelerated MDS-associated leukemogenesis via S100a9. Blood. PMID 32202636 DOI: 10.1182/blood.2019001963  0.324
2019 Man N, Mas Martin G, Karl D, Sun J, Liu F, Torres-Martin M, Itonaga H, Martinez C, Chen S, Duffort S, Hamard P, Xu Y, Cimmino L, Yang F, Cole PA, ... ... Nimer S, et al. EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression Blood. 134: 561-561. DOI: 10.1182/Blood-2019-130507  0.439
2018 Greenblatt SM, Man N, Hamard PJ, Asai T, Karl D, Martinez C, Bilbao D, Stathais V, McGrew-Jermacowicz A, Duffort S, Tadi M, Blumenthal E, Newman S, Vu L, Xu Y, ... ... Nimer SD, et al. CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis. Cancer Cell. 33: 1111-1127.e5. PMID 29894694 DOI: 10.1016/j.ccell.2018.05.007  0.304
2018 Mookhtiar AK, Greenblatt S, Man N, Karl D, Stathias V, Schurer S, Nimer SD. CARM1 Inhibition: Evaluation of Response and Efficacy in Acute Myeloid Leukemia Blood. 132: 2719-2719. DOI: 10.1182/BLOOD-2018-99-114981  0.327
2018 Zhu G, Luo H, Chen S, Lai Q, Guo Y, Guryanova OA, Qiu Y, Yang F, Li W, Nimer SD, Huang S, Xu M. Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis Blood. 132: 886-886. DOI: 10.1182/Blood-2018-99-112232  0.338
2017 Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, ... ... Nimer SD, et al. Gain-of-function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies. Blood. PMID 29113963 DOI: 10.1182/Blood-2017-06-789669  0.303
2017 Kaushik S, Liu F, Veazey K, Gao G, Das P, Neves L, Li K, Zhong Y, Lu Y, Giuliani V, Bedford MT, Nimer SD, Santos MA. Genetic deletion or small molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML. Leukemia. PMID 28663579 DOI: 10.1038/Leu.2017.206  0.301
2017 Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Guo Y, Yang H, Man N, Greenblatt S, Li Z, Guo Z, Zhou Y, Wang L, Morey L, ... ... Nimer SD, et al. Loss of Asxl2 leads to myeloid malignancies in mice. Nature Communications. 8: 15456. PMID 28593990 DOI: 10.1038/Ncomms15456  0.348
2016 Cheng G, Liu F, Asai T, Lai F, Man N, Xu H, Chen S, Greenblatt S, Hamard PJ, Ando K, Martinez C, Tadi M, Wang L, Xu M, Yang FC, ... ... Nimer SD, et al. Loss of p300 accelerates MDS-associated leukemogenesis. Leukemia. PMID 27881875 DOI: 10.1038/Leu.2016.347  0.404
2016 Man N, Sun XJ, Tan Y, Garcia-Cao M, Liu F, Cheng G, Hatlen M, Xu H, Shah R, Chastain N, Liu N, Huang G, Zhou Y, Sheng M, Song J, ... ... Nimer SD, et al. Differential role of Id1 in MLL-AF9-driven leukemia based on cell of origin. Blood. PMID 26944543 DOI: 10.1182/Blood-2015-11-677708  0.345
2016 Taggart J, Ho TC, Amin E, Xu H, Barlowe TS, Perez AR, Durham BH, Tivnan P, Okabe R, Chow A, Vu L, Park SM, Prieto C, Famulare C, Patel M, ... ... Nimer SD, et al. MSI2 is required for maintaining activated myelodysplastic syndrome stem cells. Nature Communications. 7: 10739. PMID 26898884 DOI: 10.1038/Ncomms10739  0.343
2016 Man N, Tan Y, Liu F, Cheng G, Greenblatt SM, Martinez C, Sun X, Nimer SD, Wang L. Caspase-3 Can Promote Acute Myeloid Leukemia Development By Regulation of Autophagy Blood. 128: 2714-2714. DOI: 10.1182/Blood.V128.22.2714.2714  0.321
2016 Ando K, Hamard P, Liu F, Martinez C, Ban Y, Chen X, Nimer SD. The AML-Associated FLT3-ITD Kinase Regulates Histone Modifications and Cytokine Signaling, Via Effects on PRMT5 Blood. 128: 2696-2696. DOI: 10.1182/Blood.V128.22.2696.2696  0.327
2016 Xu Y, Man N, Martinez C, Martinez C, Beckedorf F, Cheng G, Greenblatt SM, Wang L, Shiekhattar R, Nimer SD. TAFII250 Is Critical in AML1-ETO Mediated Leukemogenesis Blood. 128: 1520-1520. DOI: 10.1182/Blood.V128.22.1520.1520  0.362
2016 Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Ying G, Yang H, Nimer SD, Wang Q, Xu M, Yang F. ASXL2 Is Required for Normal Hematopoiesis and Loss of asxl2 Leads to Myeloid Malignancies in Mice Blood. 128: 1509-1509. DOI: 10.1182/blood.v128.22.1509.1509  0.36
2015 Liu F, Cheng G, Hamard PJ, Greenblatt S, Wang L, Man N, Perna F, Xu H, Tadi M, Luciani L, Nimer SD. Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis. The Journal of Clinical Investigation. PMID 26258414 DOI: 10.1172/Jci81749  0.352
2015 Perna F, Vu LP, Themeli M, Kriks S, Hoya-Arias R, Khanin R, Hricik T, Mansilla-Soto J, Papapetrou EP, Levine RL, Studer L, Sadelain M, Nimer SD. The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells. Stem Cell Reports. 4: 658-69. PMID 25754204 DOI: 10.1016/J.Stemcr.2015.02.003  0.332
2015 Ho T, Taggart J, Amin E, Xu H, Barlowe T, Perez AR, Tivnan P, Okabe R, Lengner C, Verma A, Roboz GJ, Guzman ML, Leslie CS, Nimer SD, Kharas MG. MSI2 Is Required for Maintaining the Activated Myelodysplastic Syndrome Stem Cell Blood. 126: 714-714. DOI: 10.1182/Blood.V126.23.714.714  0.346
2015 Hatlen MA, Arora K, Vacic V, Grabowska EA, Liao W, Riley-Gillis B, Oschwald DM, Wang L, Joergens JE, Shih AH, Rapaport F, Gu S, Voza F, Asai T, Neel B, ... ... Nimer SD, et al. Integrative Analysis of the Mutational Landscape of Mouse and Human AML Identifies Functionally Relevant Leukemia Disease Alleles Blood. 126: 1247-1247. DOI: 10.1182/blood.v126.23.1247.1247  0.305
2015 Hamard P, Luciani L, Liu F, Cheng G, Hatlen MA, Guryanova OA, Zhao X, Levine RL, Nimer SD. Prmt5 Negatively Regulates Erythropoiesis By Multiple Mechanisms, Including Controlling DNA Methyltransferase 3A Protein Levels Blood. 126: 1181-1181. DOI: 10.1182/Blood.V126.23.1181.1181  0.318
2014 Greenblatt SM, Nimer SD. Chromatin modifiers and the promise of epigenetic therapy in acute leukemia. Leukemia. 28: 1396-406. PMID 24609046 DOI: 10.1038/leu.2014.94  0.334
2014 Xu H, Deblassio TR, Armstrong SA, Nimer S. Role of p21 in a Mouse Model of NUP98-HOXD13 Fusion Driven Myelodysplastic Syndromes (MDS) Blood. 124: 4616-4616. DOI: 10.1182/Blood.V124.21.4616.4616  0.345
2014 LIU F, Cheng G, Perna F, Haiming X, Hamard P, Luciani L, Nimer S. PRMT5 Methyltransferase Activity Is Required to Sustain Adult Hematopoiesis Blood. 124: 4335-4335. DOI: 10.1182/Blood.V124.21.4335.4335  0.384
2014 Yan X, Hayashi Y, Zhao X, Chen A, Zhang Y, He F, Dong Y, Rao Y, Li B, Conway R, Maiques-Díaz A, Huang N, Elf SE, Zuber J, Xiao Z, ... ... Nimer SD, et al. RUNX1/CBFβ Dosage Is Critical for MLL Leukemias Development Blood. 124: 2187-2187. DOI: 10.1182/Blood.V124.21.2187.2187  0.303
2013 Asai T, Liu Y, Nimer SD. Necdin, a p53 target gene, in stem cells. Oncotarget. 4: 806-7. PMID 23867447 DOI: 10.18632/oncotarget.997  0.324
2013 Ando K, Tsushima H, Matsuo E, Horio K, Tominaga-Sato S, Imanishi D, Imaizumi Y, Iwanaga M, Itonaga H, Yoshida S, Hata T, Moriuchi R, Kiyoi H, Nimer S, Mano H, et al. Mutations in the nucleolar phosphoprotein, nucleophosmin, promote the expression of the oncogenic transcription factor MEF/ELF4 in leukemia cells and potentiates transformation. The Journal of Biological Chemistry. 288: 9457-67. PMID 23393136 DOI: 10.1074/Jbc.M112.415703  0.395
2012 Bazzoli E, Pulvirenti T, Oberstadt MC, Perna F, Wee B, Schultz N, Huse JT, Fomchenko EI, Voza F, Tabar V, Brennan CW, DeAngelis LM, Nimer SD, Holland EC, Squatrito M. MEF promotes stemness in the pathogenesis of gliomas. Cell Stem Cell. 11: 836-44. PMID 23217424 DOI: 10.1016/J.Stem.2012.09.012  0.31
2012 Liu Y, Liu F, Yu H, Zhao X, Sashida G, Deblasio A, Harr M, She QB, Chen Z, Lin HK, Di Giandomenico S, Elf SE, Yang Y, Miyata Y, Huang G, ... ... Nimer SD, et al. Akt phosphorylates the transcriptional repressor Bmi1 to block its effects on the tumor-suppressing Ink4a-Arf locus Science Signaling. 5. PMID 23092893 DOI: 10.1126/Scisignal.2003199  0.333
2012 Xu H, Menendez S, Schlegelberger B, Bae N, Aplan PD, Göhring G, Deblasio TR, Nimer SD. Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model. Blood. 120: 3089-97. PMID 22927245 DOI: 10.1182/Blood-2012-01-405332  0.71
2012 Asai T, Liu Y, Di Giandomenico S, Bae N, Ndiaye-Lobry D, Deblasio A, Menendez S, Antipin Y, Reva B, Wevrick R, Nimer SD. Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells. Blood. 120: 1601-12. PMID 22776820 DOI: 10.1182/Blood-2011-11-393983  0.727
2012 Landau HJ, McNeely SC, Nair JS, Comenzo RL, Asai T, Friedman H, Jhanwar SC, Nimer SD, Schwartz GK. The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells. Molecular Cancer Therapeutics. 11: 1781-8. PMID 22653969 DOI: 10.1158/1535-7163.MCT-11-0949  0.335
2012 Klimek VM, Dolezal EK, Jurcic JG, Devlin S, Zikaras K, Park JH, Rosenblat TL, Nimer S. Phase 2 Study of Decitabine in Combination with Tretinoin in Myelodysplastic Syndromes and Acute Myelogenous Leukemia: Interim Results Blood. 120: 3815-3815. DOI: 10.1182/Blood.V120.21.3815.3815  0.307
2012 Perna F, Vu LP, Themeli M, Hoya-Arias R, Liu F, Wang L, Gurvich N, Hricik T, Papapetrou EP, Moore MAA, Levine RL, Sadelain M, Nimer S. L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis. Blood. 120: 2296-2296. DOI: 10.1182/Blood.V120.21.2296.2296  0.441
2012 Rodina A, Moulick K, Ahn J, Zong H, Cerchietti L, DaGama EG, Caldas-Lopes E, Beebe K, Perna F, Hatzi K, Vu L, Zhao X, Zatorska D, Taldone T, Smith-Jones P, ... ... Nimer S, et al. Abstract 3029: Biochemical evidence towards the existence of an oncogenic Hsp90 complex Cancer Research. 72: 3029-3029. DOI: 10.1158/1538-7445.Am2012-3029  0.361
2011 Wang L, Gural A, Sun XJ, Zhao X, Perna F, Huang G, Hatlen MA, Vu L, Liu F, Xu H, Asai T, Xu H, Deblasio T, Menendez S, Voza F, ... ... Nimer SD, et al. The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Science (New York, N.Y.). 333: 765-9. PMID 21764752 DOI: 10.1126/Science.1201662  0.304
2011 Asai T, Liu Y, Bae N, Nimer SD. The p53 tumor suppressor protein regulates hematopoietic stem cell fate. Journal of Cellular Physiology. 226: 2215-21. PMID 21660944 DOI: 10.1002/Jcp.22561  0.728
2011 Sashida G, Bae N, Di Giandomenico S, Asai T, Gurvich N, Bazzoli E, Liu Y, Huang G, Zhao X, Menendez S, Nimer SD. The mef/elf4 transcription factor fine tunes the DNA damage response. Cancer Research. 71: 4857-65. PMID 21616937 DOI: 10.1158/0008-5472.Can-11-0455  0.678
2011 Gruber TA, Gedman AL, Ta HQ, Zhang J, Koss C, Chen S, Su X, Gupta V, Ogden S, Andersson AK, Easton J, Wang J, Rusch M, Ding L, Cazzaniga G, ... ... Nimer SD, et al. Transcriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases: A Report From the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project Blood. 118: 757-757. DOI: 10.1182/Blood.V118.21.757.757  0.307
2011 Abdel-Wahab O, Adli M, Saunders L, Gao J, Shih AH, Pandey S, Jaffe J, Zhao X, Perna F, Carroll M, Melnick A, Nimer SD, Aifantis I, Bernstein B, Levine RL. ASXL1 Mutations Promote Myeloid Transformation Through Inhibition of PRC2-Mediated Gene Repression Blood. 118: 405-405. DOI: 10.1182/Blood.V118.21.405.405  0.306
2011 Perna F, Vu LP, Themeli M, Hoya-Arias R, Zhao X, Papapetrou EP, Sadelain M, Nimer SD. Targeting a Novel Epigenetic Silencing Mechanism to Efficiently Upregulate Fetal Globin Gene Expression Blood. 118: 352-352. DOI: 10.1182/Blood.V118.21.352.352  0.303
2011 Zhao X, Vu LP, Perna F, Liu F, Xu H, Nimer S. Methylation of RUNX1 by the Nuclear PRMT5/COPR5 Complex Regulates Its Cellular Location in Leukemia Cells, Blood. 118: 3403-3403. DOI: 10.1182/Blood.V118.21.3403.3403  0.345
2011 Harr MW, Zhao X, Klein M, Liu F, Hatlen M, Nimer S. JAK2 V617F, PRMT5, and GATA-1 Form a Regulatory Loop That Controls Autophagy Via Effects on ATG3 Gene Expression Blood. 118: 2822-2822. DOI: 10.1182/Blood.V118.21.2822.2822  0.398
2010 Perna F, Gurvich N, Hoya-Arias R, Abdel-Wahab O, Levine RL, Asai T, Voza F, Menendez S, Wang L, Liu F, Zhao X, Nimer SD. Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera. Blood. 116: 2812-21. PMID 20585043 DOI: 10.1182/blood-2010-02-270611  0.31
2010 Landau H, Hassoun H, Rosenzweig MA, Bello C, Hoover E, Riedel E, Lesokhin A, Lendvai N, Cohen A, Nimer S, Comenzo RL. Maintained Hematologic and Organ Responses at Two Years Following Stem Cell Transplant In Systemic Light-Chain Amyloidosis (AL) Using Short-Course Bortezomib and Dexamethasone Consolidation Therapy Blood. 116: 2391-2391. DOI: 10.1182/Blood.V116.21.2391.2391  0.361
2010 Lopes EC, Gozman A, Taldone T, Ahn J, Marubayashi S, Rudin C, Levine RL, Nimer S, Chiosis G. Determinants of Apoptotic Sensitivity to HSP90 Inhibition In Acute Myeloid Leukemia Blood. 116: 2159-2159. DOI: 10.1182/Blood.V116.21.2159.2159  0.382
2010 Wang L, Gural A, Perna F, Sun X, Zhao X, Xu H, Hatlen MA, Huang G, Liu F, Xu H, Deblasio T, Menendez S, Voza F, Roeder R, Nimer S. The Acetylation of AML1-ETO Is Required for Leukemogenesis. Blood. 116: 1588-1588. DOI: 10.1182/Blood.V116.21.1588.1588  0.474
2010 Fein DE, Hassoun H, Comenzo RL, Lesokhin A, Lendvai N, Chung D, Cohen A, Rosenzweig MA, Chimento D, Jia X, Nimer S, Giralt S, Landau H. Outcomes Following Salvage Autologous Stem Cell Transplant for Multiple Myeloma Blood. 116: 1353-1353. DOI: 10.1182/Blood.V116.21.1353.1353  0.368
2009 Liu Y, Hoya-Arias R, Nimer SD. The role of p53 in limiting somatic cell reprogramming. Cell Research. 19: 1227-8. PMID 19881523 DOI: 10.1038/Cr.2009.121  0.326
2009 Liu Y, Elf SE, Asai T, Miyata Y, Liu Y, Sashida G, Huang G, Di Giandomenico S, Koff A, Nimer SD. The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior. Cell Cycle (Georgetown, Tex.). 8: 3120-4. PMID 19755852 DOI: 10.4161/Cc.8.19.9627  0.423
2009 Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL, Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nature Cell Biology. 11: 420-32. PMID 19270694 DOI: 10.1038/Ncb1849  0.358
2009 Liu Y, Elf SE, Miyata Y, Sashida G, Liu Y, Huang G, Di Giandomenico S, Lee JM, Deblasio A, Menendez S, Antipin J, Reva B, Koff A, Nimer SD. p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell. 4: 37-48. PMID 19128791 DOI: 10.1016/J.Stem.2008.11.006  0.438
2009 Asai T, Liu Y, Giandomenico SD, Deblasio A, Menendez S, Antipin J, Reva B, Wevrick R, Nimer SD. Necdin Regulates Hematopoietic Stem Cell Quiescence and Sensitivity to Genotoxic Stress. Blood. 114: 379-379. DOI: 10.1182/Blood.V114.22.379.379  0.383
2009 Gurvich N, Voza F, Menendez S, Nimer S. Loss of L3MBTL1, a Candidate 20q12 Tumor Suppressor Gene, Leads to DNA Damage. Blood. 114: 1974-1974. DOI: 10.1182/Blood.V114.22.1974.1974  0.441
2008 Thompson BJ, Jankovic V, Gao J, Buonamici S, Vest A, Lee JM, Zavadil J, Nimer SD, Aifantis I. Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7. The Journal of Experimental Medicine. 205: 1395-408. PMID 18474632 DOI: 10.1084/Jem.20080277  0.316
2008 Morales M, Liu Y, Laiakis EC, Morgan WF, Nimer SD, Petrini JH. DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions. Cancer Research. 68: 2186-93. PMID 18381424 DOI: 10.1158/0008-5472.Can-07-2355  0.307
2008 Zhou P, Boruchov AM, Hoffman JE, Mo Q, Olshen A, Glasner E, Bonvini E, Koenig S, Drieghe E, Fleisher M, Maslak P, Hassoun H, Cohen AD, Landau H, Young JW, ... ... Nimer SD, et al. CD32B Expression Reflects Phenotypic and Functional Heterogeneity in Multiple Myeloma (MM) Blood. 112: 842-842. DOI: 10.1182/Blood.V112.11.842.842  0.312
2008 Cohen AD, Lu P, Gnjatic S, Hoffman J, Ritter E, Zhou P, Teruya-Feldstein J, Tassello J, Hanson N, Frosina D, Jungbluth A, Koehne G, Hassoun H, Jhanwar S, Landau H, ... Nimer S, et al. MAGE-A3 or NY-ESO1 Expression and Spontaneous Antibody Responses to NY-ESO1 in Newly Diagnosed Multiple Myeloma Patients Are Associated with Worse Overall Survival Blood. 112: 5110-5110. DOI: 10.1182/Blood.V112.11.5110.5110  0.344
2008 Perna F, Gurvich N, Hoya-Arias R, Voza F, Jankovic V, Kalakonda N, Nimer SD. Depletion of L3MBTL1, a PcG Gene Deleted in Patients with 20q-Associated with Hematologic Malignancies, Accelerates Erythroid Differentiation of Hematopoietic Progenitor Cells Blood. 112: 3740-3740. DOI: 10.1182/BLOOD.V112.11.3740.3740  0.308
2008 Hoffman JE, Hassoun H, Landau H, Hoover E, Cohen A, Nimer S, Comenzo R. Early Adjuvant Treatment after Risk-Adapted Autologous Stem Cell Transplant for Systemic Light-Chain Amyloidosis: Increased Hospitalizations and Impaired Immune Recovery but Improved Responses and Overall Survival. Blood. 112: 3329-3329. DOI: 10.1182/Blood.V112.11.3329.3329  0.39
2008 Huang G, Elf S, Yan X, Wang L, Liu Y, Sashida G, Gural A, Menendez S, Lee J, Yang Y, Zhao X, Nimer SD. Previously Unknown Interactions Between AML1 and MLL Provide Epigenetic Regulation of Gene Expression in Normal Hematopoiesis and in Leukemia Blood. 112: 282-282. DOI: 10.1182/Blood.V112.11.282.282  0.306
2007 Ciarrocchi A, Jankovic V, Shaked Y, Nolan DJ, Mittal V, Kerbel RS, Nimer SD, Benezra R. Id1 restrains p21 expression to control endothelial progenitor cell formation. Plos One. 2: e1338. PMID 18092003 DOI: 10.1371/Journal.Pone.0001338  0.321
2007 Liu Y, Elf SE, Miyata Y, Sashida G, Deblasio AD, Liu Y, Koff A, Nimer SD. Regulation of Hematopoietic Stem Cell Quiescence - A Novel Role for p53. Blood. 110: 92-92. DOI: 10.1182/Blood.V110.11.92.92  0.358
2007 Spielberger R, Territo M, Durrant S, Nimer S, McCarty J, Hurd D, Berger D, Aycock J, Chen M, Stiff P. No Difference in Survival or Long-Term Disease Outcomes in Palifermin-Treated Patients with Hematologic Malignancies Undergoing Hematopoietic Stem Cell Transplantation. Blood. 110: 1664-1664. DOI: 10.1182/Blood.V110.11.1664.1664  0.343
2006 Pabst T, Stillner E, Neuberg D, Nimer S, Willman CL, List AF, Melo JV, Tenen DG, Mueller BU. Mutations of the myeloid transcription factor CEBPA are not associated with the blast crisis of chronic myeloid leukaemia. British Journal of Haematology. 133: 400-2. PMID 16643447 DOI: 10.1111/J.1365-2141.2006.06057.X  0.329
2006 Lacorazza HD, Yamada T, Liu Y, Miyata Y, Sivina M, Nunes J, Nimer SD. The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells. Cancer Cell. 9: 175-87. PMID 16530702 DOI: 10.1016/J.Ccr.2006.02.017  0.343
2006 Maslak P, Chanel S, Camacho LH, Soignet S, Pandolfi PP, Guernah I, Warrell R, Nimer S. Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome. Leukemia. 20: 212-7. PMID 16357841 DOI: 10.1038/Sj.Leu.2404050  0.377
2006 Miyata Y, Lie Y, Sashida G, Nimer S. The Role of Cyclin C on Hematopoietic Cells. Blood. 108: 4238-4238. DOI: 10.1182/Blood.V108.11.4238.4238  0.405
2006 Gural A, Jankovic V, Zhang J, Roeder RG, Nimer SD. The Deletion of NHR1 Region of the AML1-ETO Protein Significantly Decreases Its Ability To Promote Proliferation and Self-Renewal of Early Hematopoietic Cells in Culture. Blood. 108: 2550-2550. DOI: 10.1182/Blood.V108.11.2550.2550  0.324
2006 Liu Y, Miyata Y, Sashida G, Debalsio A, Liu Y, Koff A, Nimer SD. Genetic Uncoupling of the Regulation of Hematopoietic Stem Cell Quiescence and Self-Renewal. Blood. 108: 1347-1347. DOI: 10.1182/Blood.V108.11.1347.1347  0.365
2006 Jankovic V, Ciarrocchi A, DeBlasio T, Benezra R, Nimer SD. Identification of Key Cellular Regulators That Interact with Id1 To Control Hematopoietic Stem Cell Behavior. Blood. 108: 1319-1319. DOI: 10.1182/Blood.V108.11.1319.1319  0.397
2005 Moskowitz CH, Zelenetz AD, Kewalramani T, Hamlin P, Lessac-Chenen S, Houldsworth JD, Olshen A, Chaganti R, Nimer S, Teruya-Feldstein J. Cell of origin, germinal center versus nongerminal center, determined by immunohistochemistry on tissue microarray, does not correlate with outcome in patients with relapsed and refractory DLBCL Blood. 106: 3383-3385. PMID 16091454 DOI: 10.1182/Blood-2005-04-1603  0.369
2005 Zhu H, Traver D, Davidson AJ, Dibiase A, Thisse C, Thisse B, Nimer S, Zon LI. Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Developmental Biology. 281: 256-69. PMID 15893977 DOI: 10.1016/J.Ydbio.2005.01.034  0.381
2005 Jankovic V, Ciarrocchi A, Boccuni P, Benezra R, Nimer SD. Id1 Regulates the Choice of Hematopoietic Stem Cells to Self-Renew or Commit to Differentiation. Blood. 106: 270-270. DOI: 10.1182/Blood.V106.11.270.270  0.338
2005 Horwitz S, Moskowitz C, Kewalramani T, Hamlin P, Straus D, O’Connor O, Noy A, Portlock C, Nimer S, Palomba ML, Zelenetz A. Second-Line Therapy with ICE Followed by High Dose Therapy and Autologous Stem Cell Transplantation for Relapsed/Refractory Peripheral T-Cell Lymphomas: Minimal Benefit When Analyzed by Intent To Treat. Blood. 106: 2679-2679. DOI: 10.1182/Blood.V106.11.2679.2679  0.328
2005 Persky D, Teruya-Feldstein J, Kewalramani T, Bonner PD, Iasonos A, Rice D, Yahalom J, Nimer SD, Zelenetz AD, Moskowitz CH. High Dose Chemoradiotherapy and ASCT Can Overcome the Prognostic Importance of Bcl-2, Bim, and p53 in Relapsed/Refractory Hodgkin’s Lymphoma. Blood. 106: 2073-2073. DOI: 10.1182/BLOOD.V106.11.2073.2073  0.325
2005 Klimek V, Fircanis S, Maslak P, Pandolfi P, Guernah I, Baum M, DeBlasio T, Wright J, Sognet S, Nimer S. P-118 Pilot trial of the histone deacetylase inhibitor depsipeptide in patients with acute myelogenous leukemia (AML) and myelodysplastic syndromes (MDS) Leukemia Research. 29: S69. DOI: 10.1016/S0145-2126(05)80182-1  0.351
2004 Scandura JM, Boccuni P, Massagué J, Nimer SD. Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation. Proceedings of the National Academy of Sciences of the United States of America. 101: 15231-6. PMID 15477587 DOI: 10.1073/Pnas.0406771101  0.396
2004 Nimer SD, Moore MA. Effects of the leukemia-associated AML1-ETO protein on hematopoietic stem and progenitor cells. Oncogene. 23: 4249-54. PMID 15156180 DOI: 10.1038/sj.onc.1207673  0.32
2004 Heidel F, Breitenbuecher F, Kindler T, Solem FK, Carius B, Thiede H-, Cohen PS, Roesel J, Estey EH, Feldman E, Ehninger G, Schiller GJ, Klimek V, Nimer S, DeAngelo D, et al. Mechanisms of Resistance to the FLT3-Tyrosine Kinase Inhibitor PKC412 in Patients with AML. Blood. 104: 454-454. DOI: 10.1182/Blood.V104.11.454.454  0.343
2004 Zhao X, Parkanani A, Zhang J, Dunne R, Xiao A, Allis CD, Nimer S. Arginine Methylation of Runx1 Regulates Its Biological and Transcriptional Activities. Blood. 104: 2041-2041. DOI: 10.1182/Blood.V104.11.2041.2041  0.39
2003 Zelenetz AD, Hamlin P, Kewalramani T, Yahalom J, Nimer S, Moskowitz CH. Ifosfamide, carboplatin, etoposide (ICE)-based second-line chemotherapy for the management of relapsed and refractory aggressive non-Hodgkin's lymphoma Annals of Oncology. 14. PMID 12736224 DOI: 10.1093/Annonc/Mdg702  0.352
2002 Mulloy JC, Cammenga J, MacKenzie KL, Berguido FJ, Moore MA, Nimer SD. The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells. Blood. 99: 15-23. PMID 11756147 DOI: 10.1182/Blood.V99.1.15  0.353
1999 Gajewski JL, Nimer S, Saliba RM, Thomas M, Przepiorka D, Giralt S, von Besien K, Mehra R, Andersson B, Chan KW, Ippoliti C, Warkinten D, Feigs S, Territo M, Schiller G, et al. Long-term outcome of a phase II study of BM transplants, partially depleted ex-vivo of CD5-positive and CD8-positive T-lymphocytes in unrelated and related donor 1 antigen mismatched recipients. Cytotherapy. 1: 401-7. PMID 20426540 DOI: 10.1080/0032472031000141284  0.308
1996 Nimer S, Zhang J, Avraham H, Miyazaki Y. Transcriptional regulation of interleukin-3 expression in megakaryocytes Blood. 88: 66-74. DOI: 10.1182/Blood.V88.1.66.Bloodjournal88166  0.33
1996 Nimer S, Zhang W, Kwan K, Whang Y, Zhang J, Wang Y [corrected to Whang Y. Adjacent, cooperative elements form a strong, constitutive enhancer in the human granulocyte-macrophage colony-stimulating factor gene [published erratum appears in Blood 1996 Oct 1;88(7):2818] Blood. 87: 3694-3703. DOI: 10.1182/Blood.V87.9.3694.Bloodjournal8793694  0.315
1992 Schiller G, Gajewski J, Territo M, Nimer S, Lee M, Belin T, Champlin R. Long-term outcome of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia Blood. 80: 2977-2982. DOI: 10.1182/Blood.V80.12.2977.Bloodjournal80122977  0.336
1992 Nichols J, Nimer S. Transcription factors, translocations, and leukemia Blood. 80: 2953-2963. DOI: 10.1182/BLOOD.V80.12.2953.BLOODJOURNAL80122953  0.319
1992 Nichols J, Nimer S. Transcription factors, translocations, and leukemia Blood. 80: 2953-2963. DOI: 10.1182/blood.v80.12.2953.2953  0.319
1990 Champlin R, Gajewski J, Nimer S, Vollset S, Landaw E, Winston D, Schiller G, Ho W. Postremission chemotherapy for adults with acute myelogenous leukemia: improved survival with high-dose cytarabine and daunorubicin consolidation treatment Journal of Clinical Oncology. 8: 1199-1206. PMID 1694236 DOI: 10.1200/Jco.1990.8.7.1199  0.357
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