| Year |
Citation |
Score |
| 2022 |
Kulkarni AS, Aleksic S, Berger DM, Sierra F, Kuchel GA, Barzilai N. Geroscience-guided repurposing of FDA-approved drugs to target aging: A proposed process and prioritization. Aging Cell. e13596. PMID 35343051 DOI: 10.1111/acel.13596 |
0.663 |
|
| 2020 |
Kulkarni AS, Peck BD, Walton RG, Kern PA, Mar JC, Windham ST, Bamman MM, Barzilai N, Peterson CA. Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults. Aging. 12. PMID 33071237 DOI: 10.18632/aging.104096 |
0.658 |
|
| 2020 |
Justice JN, Gubbi S, Kulkarni AS, Bartley JM, Kuchel GA, Barzilai N. A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin. Geroscience. PMID 32902818 DOI: 10.1007/s11357-020-00261-6 |
0.649 |
|
| 2020 |
Barzilai N, Appleby JC, Austad SN, Cuervo AM, Kaeberlein M, Gonzalez-Billault C, Lederman S, Stambler I, Sierra F. Geroscience in the Age of COVID-19. Aging and Disease. 11: 725-729. PMID 32765937 DOI: 10.14336/Ad.2020.0629 |
0.31 |
|
| 2020 |
Sathyan S, Ayers E, Gao T, Milman S, Barzilai N, Verghese J. Plasma proteomic profile of frailty. Aging Cell. e13193. PMID 32762010 DOI: 10.1111/Acel.13193 |
0.301 |
|
| 2020 |
Zhang WB, Aleksic S, Gao T, Weiss EF, Demetriou E, Verghese J, Holtzer R, Barzilai N, Milman S. Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults. Cells. 9. PMID 32492897 DOI: 10.3390/Cells9061368 |
0.351 |
|
| 2020 |
Kulkarni AS, Gubbi S, Barzilai N. Benefits of Metformin in Attenuating the Hallmarks of Aging. Cell Metabolism. PMID 32333835 DOI: 10.1016/J.Cmet.2020.04.001 |
0.689 |
|
| 2020 |
Rozanov L, Ravichandran M, Grigolon G, Zanellati MC, Mansfeld J, Zarse K, Barzilai N, Atzmon G, Fischer F, Ristow M. Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A. Redox Biology. 32: 101448. PMID 32203922 DOI: 10.1016/J.Redox.2020.101448 |
0.368 |
|
| 2019 |
Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T. Undulating changes in human plasma proteome profiles across the lifespan. Nature Medicine. 25: 1843-1850. PMID 31806903 DOI: 10.1038/S41591-019-0673-2 |
0.367 |
|
| 2019 |
Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB, Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, et al. Latest advances in aging research and drug discovery. Aging. 11. PMID 31770722 DOI: 10.18632/Aging.102487 |
0.33 |
|
| 2019 |
Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, ... ... Barzilai N, et al. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature Communications. 10: 3669. PMID 31413261 DOI: 10.1038/S41467-019-11558-2 |
0.33 |
|
| 2019 |
Newman JC, Sokoloski JL, Robbins PD, Niedernhofer LJ, Reed MJ, Wei J, Austad SN, Barzilai N, Cohen HJ, Kuchel GA, Kirkland JL, Pignolo RJ. Creating the Next Generation of Translational Geroscientists. Journal of the American Geriatrics Society. PMID 31287934 DOI: 10.1111/Jgs.16055 |
0.303 |
|
| 2019 |
Hurria A, Carpenter CR, McFarland F, Lundebjerg NE, de Cabo R, Ferrucci L, Studenski SA, Barzilai N, Briggs JP, Ix JH, Kitzman DW, Kuchel GA, Musi N, Newman JC, Rando TA, et al. Models and Studies of Aging: Executive Summary of a Report from the U13 Conference Series. Journal of the American Geriatrics Society. PMID 30693953 DOI: 10.1111/Jgs.15788 |
0.341 |
|
| 2019 |
Fleming GA, Zhao JH, Seoh TC, Barzilai N. A Regulatory Pathway for Medicines That Target Aging Public Policy & Aging Report. 29: 128-133. DOI: 10.1093/Ppar/Prz018 |
0.309 |
|
| 2019 |
Justice JN, Kuchel GA, Barzilai N, Kritchevsky S. BIOMARKER STRATEGIES FOR GEROSCIENCE-GUIDED CLINICAL TRIALS Innovation in Aging. 3: S745-S746. DOI: 10.1093/Geroni/Igz038.2731 |
0.331 |
|
| 2019 |
Kulkarni AS, Mar JC, Barzilai N. INVESTIGATING DYNAMICS OF AGE-ASSOCIATED TRANSCRIPTIONAL NETWORKS WITH INTERVENTIONS TARGETING AGING Innovation in Aging. 3: S559-S559. DOI: 10.1093/Geroni/Igz038.2066 |
0.69 |
|
| 2018 |
Walters RO, Arias E, Diaz A, Burgos ES, Guan F, Tiano S, Mao K, Green CL, Qiu Y, Shah H, Wang D, Hudgins AD, Tabrizian T, Tosti V, Shechter D, ... ... Barzilai N, et al. Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans. Cell Reports. 25: 663-676.e6. PMID 30332646 DOI: 10.1016/J.Celrep.2018.09.065 |
0.373 |
|
| 2018 |
Sebastiani P, Gurinovich A, Nygaard M, Sasaki T, Sweigart B, Bae H, Andersen SL, Villa F, Atzmon G, Christensen K, Arai Y, Barzilai N, Puca A, Christiansen L, Hirose N, et al. APOE Alleles and Extreme Human Longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30060062 DOI: 10.1093/Gerona/Gly174 |
0.34 |
|
| 2018 |
Mao K, Quipildor GF, Tabrizian T, Novaj A, Guan F, Walters RO, Delahaye F, Hubbard GB, Ikeno Y, Ejima K, Li P, Allison DB, Salimi-Moosavi H, Beltran PJ, Cohen P, ... Barzilai N, et al. Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice. Nature Communications. 9: 2394. PMID 29921922 DOI: 10.1038/S41467-018-04805-5 |
0.35 |
|
| 2018 |
Sathyan S, Barzilai N, Atzmon G, Milman S, Ayers E, Verghese J. Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty. Frontiers in Medicine. 5: 105. PMID 29765957 DOI: 10.3389/Fmed.2018.00105 |
0.323 |
|
| 2018 |
Gubbi S, Quipildor GF, Barzilai N, Huffman DM, Milman S. IGF-1: The Jekyll & Hyde of the aging brain. Journal of Molecular Endocrinology. PMID 29739805 DOI: 10.1530/Jme-18-0093 |
0.356 |
|
| 2018 |
Kulkarni AS, Brutsaert EF, Anghel V, Zhang K, Bloomgarden N, Pollak M, Mar JC, Hawkins M, Crandall JP, Barzilai N. Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. Aging Cell. PMID 29383869 DOI: 10.1111/Acel.12723 |
0.782 |
|
| 2018 |
Barzilai N. HOW TO PROVE THAT AGING CAN BE TAMED AND THAT APPROPRIATE REGULATION CAN BE FOLLOWED? Innovation in Aging. 2: 544-544. DOI: 10.1093/Geroni/Igy023.2008 |
0.326 |
|
| 2017 |
Knight CM, Gutierrez-Juarez R, Lam TKT, Arrieta-Cruz I, Huang L, Schwartz G, Barzilai N, Rossetti L. Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700. Diabetes. 66: 3143-3144. PMID 29162736 DOI: 10.2337/Db17-Er12C |
0.327 |
|
| 2017 |
Martinez-Lopez N, Tarabra E, Toledo M, Garcia-Macia M, Sahu S, Coletto L, Batista-Gonzalez A, Barzilai N, Pessin JE, Schwartz GJ, Kersten S, Singh R. System-wide Benefits of Intermeal Fasting by Autophagy. Cell Metabolism. PMID 29107505 DOI: 10.1016/J.Cmet.2017.09.020 |
0.357 |
|
| 2017 |
Ben-Avraham D, Govindaraju DR, Budagov T, Fradin D, Durda P, Liu B, Ott S, Gutman D, Sharvit L, Kaplan R, Bougnères P, Reiner A, Shuldiner AR, Cohen P, Barzilai N, et al. The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. Science Advances. 3: e1602025. PMID 28630896 DOI: 10.1126/Sciadv.1602025 |
0.332 |
|
| 2017 |
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, ... ... Barzilai N, et al. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. PMID 28341696 DOI: 10.2337/Db16-1329 |
0.4 |
|
| 2017 |
Pollack RM, Barzilai N, Anghel V, Kulkarni AS, Golden A, O'Broin P, Sinclair DA, Bonkowski MS, Coleville AJ, Powell D, Kim S, Moaddel R, Stein D, Zhang K, Hawkins M, et al. Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28329397 DOI: 10.1093/Gerona/Glx041 |
0.754 |
|
| 2016 |
Hodes RJ, Sierra F, Austad SN, Epel E, Neigh GN, Erlandson KM, Schafer MJ, LeBrasseur NK, Wiley C, Campisi J, Sehl ME, Scalia R, Eguchi S, Kasinath BS, Halter JB, ... ... Barzilai N, et al. Disease drivers of aging. Annals of the New York Academy of Sciences. 1386: 45-68. PMID 27943360 DOI: 10.1111/Nyas.13299 |
0.323 |
|
| 2016 |
Huffman DM, Justice JN, Stout MB, Kirkland JL, Barzilai N, Austad SN. Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27535967 DOI: 10.1093/Gerona/Glw106 |
0.316 |
|
| 2016 |
Justice J, Miller JD, Newman JC, Hashmi SK, Halter J, Austad SN, Barzilai N, Kirkland JL. Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27535966 DOI: 10.1093/Gerona/Glw126 |
0.31 |
|
| 2016 |
Heo HJ, Tozour JN, Delahaye F, Zhao Y, Cui L, Barzilai N, Einstein FH. Advanced aging phenotype is revealed by epigenetic modifications in rat liver after in utero malnutrition. Aging Cell. PMID 27470058 DOI: 10.1111/Acel.12505 |
0.369 |
|
| 2016 |
Barzilai N, Crandall JP, Kritchevsky SB, Espeland MA. Metformin as a Tool to Target Aging. Cell Metabolism. 23: 1060-5. PMID 27304507 DOI: 10.1016/J.Cmet.2016.05.011 |
0.34 |
|
| 2016 |
Milman S, Huffman DM, Barzilai N. The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research. Cell Metabolism. 23: 980-9. PMID 27304500 DOI: 10.1016/J.Cmet.2016.05.014 |
0.396 |
|
| 2016 |
Marzec M, Hawkes CP, Eletto D, Boyle S, Rosenfeld R, Hwa V, Wit JM, van Duyvenvoorde HA, Oostdijk W, Losekoot M, Pedersen O, Beng Yeap B, Flicker L, Barzilai N, Atzmon G, et al. A human variant of Glucose-regulated protein 94 that inefficiently supports IGF production. Endocrinology. en20152058. PMID 26982636 DOI: 10.1210/En.2015-2058 |
0.359 |
|
| 2016 |
Milman S, Barzilai N. Dissecting the Mechanisms Underlying Unusually Successful Human Health Span and Life Span. Cold Spring Harbor Perspectives in Medicine. 6: a025098. PMID 26637439 DOI: 10.1101/Cshperspect.A025098 |
0.373 |
|
| 2015 |
Fortney K, Dobriban E, Garagnani P, Pirazzini C, Monti D, Mari D, Atzmon G, Barzilai N, Franceschi C, Owen AB, Kim SK. Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity. Plos Genetics. 11: e1005728. PMID 26677855 DOI: 10.1371/Journal.Pgen.1005728 |
0.319 |
|
| 2015 |
Huffman DM, Farias Quipildor G, Mao K, Zhang X, Wan J, Apontes P, Cohen P, Barzilai N. Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline. Aging Cell. PMID 26534869 DOI: 10.1111/Acel.12415 |
0.458 |
|
| 2015 |
Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, et al. Interventions to Slow Aging in Humans: Are We Ready? Aging Cell. 14: 497-510. PMID 25902704 DOI: 10.1111/Acel.12338 |
0.337 |
|
| 2015 |
Han J, Atzmon G, Barzilai N, Suh Y. Genetic variation in Sirtuin 1 (SIRT1) is associated with lipid profiles but not with longevity in Ashkenazi Jews. Translational Research : the Journal of Laboratory and Clinical Medicine. 165: 480-1. PMID 25305471 DOI: 10.1016/J.Trsl.2014.09.008 |
0.328 |
|
| 2014 |
Ayers E, Barzilai N, Crandall JP, Milman S, Verghese J. Association of exceptional parental longevity and physical function in aging. Age (Dordrecht, Netherlands). 36: 9677. PMID 24997018 DOI: 10.1007/S11357-014-9677-5 |
0.303 |
|
| 2014 |
Eny KM, Lutgers HL, Maynard J, Klein BE, Lee KE, Atzmon G, Monnier VM, van Vliet-Ostaptchouk JV, Graaff R, van der Harst P, Snieder H, van der Klauw MM, Sell DR, Hosseini SM, Cleary PA, ... ... Barzilai N, et al. GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence. Diabetologia. 57: 1623-34. PMID 24934506 DOI: 10.1007/S00125-014-3286-9 |
0.318 |
|
| 2014 |
Milman S, Atzmon G, Huffman DM, Wan J, Crandall JP, Cohen P, Barzilai N. Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity. Aging Cell. 13: 769-71. PMID 24618355 DOI: 10.1111/Acel.12213 |
0.314 |
|
| 2014 |
Kolovou G, Barzilai N, Caruso C, Sikora E, Capri M, Tzanetakou IP, Bilianou H, Avery P, Katsiki N, Panotopoulos G, Franceschi C, Benetos A, Mikhailidis DP. The challenges in moving from ageing to successful longevity. Current Vascular Pharmacology. 12: 662-73. PMID 24350930 DOI: 10.2174/1570161111666131219095114 |
0.344 |
|
| 2014 |
Avery P, Barzilai N, Benetos A, Bilianou H, Capri M, Caruso C, Franceschi C, Katsiki N, Mikhailidis DP, Panotopoulos G, Sikora E, Tzanetakou IP, Kolovou G. Ageing, longevity, exceptional longevity and related genetic and non genetics markers: panel statement. Current Vascular Pharmacology. 12: 659-61. PMID 24350929 DOI: 10.2174/1570161111666131219101226 |
0.338 |
|
| 2014 |
Milman S, Atzmon G, Crandall J, Barzilai N. Phenotypes and genotypes of high density lipoprotein cholesterol in exceptional longevity. Current Vascular Pharmacology. 12: 690-7. PMID 24350928 DOI: 10.2174/1570161111666131219101551 |
0.34 |
|
| 2014 |
Chang AL, Atzmon G, Bergman A, Brugmann S, Atwood SX, Chang HY, Barzilai N. Identification of genes promoting skin youthfulness by genome-wide association study. The Journal of Investigative Dermatology. 134: 651-7. PMID 24037343 DOI: 10.1038/Jid.2013.381 |
0.304 |
|
| 2013 |
Kuliawat R, Klein L, Gong Z, Nicoletta-Gentile M, Nemkal A, Cui L, Bastie C, Su K, Huffman D, Surana M, Barzilai N, Fleischer N, Muzumdar R. Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4890-8. PMID 23995290 DOI: 10.1096/Fj.13-231092 |
0.421 |
|
| 2013 |
Verghese J, Holtzer R, Wang C, Katz MJ, Barzilai N, Lipton RB. Role of APOE genotype in gait decline and disability in aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 1395-401. PMID 23902934 DOI: 10.1093/Gerona/Glt115 |
0.32 |
|
| 2013 |
Crandall JP, Barzilai N. Exploring the promise of resveratrol: where do we go from here? Diabetes. 62: 1022-3. PMID 23520278 DOI: 10.2337/Db12-1788 |
0.425 |
|
| 2013 |
Han J, Ryu S, Moskowitz DM, Rothenberg D, Leahy DJ, Atzmon G, Barzilai N, Suh Y. Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing. Mechanisms of Ageing and Development. 134: 478-85. PMID 23376243 DOI: 10.1016/J.Mad.2013.01.005 |
0.317 |
|
| 2013 |
Heo H, Huffman D, Delahaye F, Karakash S, Zhao Y, Barzilai N, Einstein F. 51: Moderate voluntary running protects against hepatic insulin resistance and restores the placenta-pup glucose uptake gradient in diet-induced obese pregnant rats American Journal of Obstetrics and Gynecology. 208: S30-S31. DOI: 10.1016/J.Ajog.2012.10.225 |
0.393 |
|
| 2012 |
Esterson YB, Kishore P, Koppaka S, Li W, Zhang K, Tonelli J, Lee DE, Kehlenbrink S, Lawrence S, Crandall J, Barzilai N, Hawkins M. Fatty acid-induced production of plasminogen activator inhibitor-1 by adipose macrophages is greater in middle-aged versus younger adult participants. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 1321-8. PMID 23089338 DOI: 10.1093/Gerona/Gls200 |
0.655 |
|
| 2012 |
Barzilai N, Ferrucci L. Insulin resistance and aging: a cause or a protective response? The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 1329-31. PMID 22859390 DOI: 10.1093/Gerona/Gls145 |
0.415 |
|
| 2012 |
Barzilai N, Guarente L, Kirkwood TB, Partridge L, Rando TA, Slagboom PE. The place of genetics in ageing research. Nature Reviews. Genetics. 13: 589-94. PMID 22777128 DOI: 10.1038/Nrg3290 |
0.336 |
|
| 2012 |
Barzilai N, Huffman DM, Muzumdar RH, Bartke A. The critical role of metabolic pathways in aging. Diabetes. 61: 1315-22. PMID 22618766 DOI: 10.2337/Db11-1300 |
0.434 |
|
| 2012 |
Huffman DM, Deelen J, Ye K, Bergman A, Slagboom EP, Barzilai N, Atzmon G. Distinguishing between longevity and buffered-deleterious genotypes for exceptional human longevity: the case of the MTP gene. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 1153-60. PMID 22496539 DOI: 10.1093/Gerona/Gls103 |
0.312 |
|
| 2012 |
Conneely KN, Capell BC, Erdos MR, Sebastiani P, Solovieff N, Swift AJ, Baldwin CT, Budagov T, Barzilai N, Atzmon G, Puca AA, Perls TT, Geesaman BJ, Boehnke M, Collins FS. Human longevity and common variations in the LMNA gene: a meta-analysis. Aging Cell. 11: 475-81. PMID 22340368 DOI: 10.1111/J.1474-9726.2012.00808.X |
0.312 |
|
| 2012 |
Crandall JP, Oram V, Trandafirescu G, Reid M, Kishore P, Hawkins M, Cohen HW, Barzilai N. Pilot study of resveratrol in older adults with impaired glucose tolerance. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 1307-12. PMID 22219517 DOI: 10.1093/Gerona/Glr235 |
0.651 |
|
| 2012 |
Ben-Shlomo S, Einstein FH, Zvibel I, Atias D, Shlomai A, Halpern Z, Barzilai N, Fishman S. Perinephric and epididymal fat affect hepatic metabolism in rats. Obesity (Silver Spring, Md.). 20: 151-6. PMID 21818154 DOI: 10.1038/Oby.2011.261 |
0.405 |
|
| 2012 |
Heo H, Karakash S, Huffman D, Delahaye F, Zhao Y, Barzilai N, Einstein F. 205: Sedentary behavior during pregnancy does not alter maternal fat distribution or insulin action American Journal of Obstetrics and Gynecology. 206: S103-S104. DOI: 10.1016/J.Ajog.2011.10.223 |
0.323 |
|
| 2012 |
Heo H, Slomko H, Karakash S, Delahaye F, Zhao Y, Huffman D, Barzilai N, Einstein F. 204: Impact of maternal diet on peripheral vs hepatic insulin resistance in young female offspring American Journal of Obstetrics and Gynecology. 206: S103. DOI: 10.1016/J.Ajog.2011.10.222 |
0.396 |
|
| 2011 |
Knight CM, Gutierrez-Juarez R, Lam TK, Arrieta-Cruz I, Huang L, Schwartz G, Barzilai N, Rossetti L. Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats. Diabetes. 60: 2691-700. PMID 21896928 DOI: 10.2337/Db10-0987 |
0.372 |
|
| 2011 |
Tazearslan C, Huang J, Barzilai N, Suh Y. Impaired IGF1R signaling in cells expressing longevity-associated human IGF1R alleles. Aging Cell. 10: 551-4. PMID 21388493 DOI: 10.1111/J.1474-9726.2011.00697.X |
0.34 |
|
| 2011 |
Ben-Shlomo S, Zvibel I, Shnell M, Shlomai A, Chepurko E, Halpern Z, Barzilai N, Oren R, Fishman S. Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase. Journal of Hepatology. 54: 1214-23. PMID 21145820 DOI: 10.1016/J.Jhep.2010.09.032 |
0.336 |
|
| 2011 |
Heo H, Hou L, Karakash S, Zhao Y, Atzmon G, Barzilai N, Einstein F. 212: Metabolic alterations in visceral fat and liver contribute to persistent insulin resistance early postpartum American Journal of Obstetrics and Gynecology. 204: S93. DOI: 10.1016/J.Ajog.2010.10.228 |
0.387 |
|
| 2010 |
Barzilai N, Gabriely I, Atzmon G, Suh Y, Rothenberg D, Bergman A. Genetic studies reveal the role of the endocrine and metabolic systems in aging. The Journal of Clinical Endocrinology and Metabolism. 95: 4493-500. PMID 20926537 DOI: 10.1210/Jc.2010-0859 |
0.378 |
|
| 2010 |
Einstein FH, Huffman DM, Fishman S, Jerschow E, Heo HJ, Atzmon G, Schechter C, Barzilai N, Muzumdar RH. Aging per se increases the susceptibility to free fatty acid-induced insulin resistance. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 65: 800-8. PMID 20504893 DOI: 10.1093/Gerona/Glq078 |
0.427 |
|
| 2010 |
Thompson RF, Atzmon G, Gheorghe C, Liang HQ, Lowes C, Greally JM, Barzilai N. Tissue-specific dysregulation of DNA methylation in aging. Aging Cell. 9: 506-18. PMID 20497131 DOI: 10.1111/J.1474-9726.2010.00577.X |
0.698 |
|
| 2010 |
Thompson RF, Fazzari MJ, Niu H, Barzilai N, Simmons RA, Greally JM. Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats. The Journal of Biological Chemistry. 285: 15111-8. PMID 20194508 DOI: 10.1074/Jbc.M109.095133 |
0.711 |
|
| 2010 |
Einstein F, Thompson RF, Bhagat TD, Fazzari MJ, Verma A, Barzilai N, Greally JM. Cytosine methylation dysregulation in neonates following intrauterine growth restriction. Plos One. 5: e8887. PMID 20126273 DOI: 10.1371/Journal.Pone.0008887 |
0.672 |
|
| 2010 |
Atzmon G, Cho M, Cawthon RM, Budagov T, Katz M, Yang X, Siegel G, Bergman A, Huffman DM, Schechter CB, Wright WE, Shay JW, Barzilai N, Govindaraju DR, Suh Y. Evolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians. Proceedings of the National Academy of Sciences of the United States of America. 107: 1710-7. PMID 19915151 DOI: 10.1073/Pnas.0906191106 |
0.351 |
|
| 2010 |
Barzilai N. Genetic and Epigenetic Contributions to Longevity Blood. 116. DOI: 10.1182/Blood.V116.21.Sci-1.Sci-1 |
0.374 |
|
| 2009 |
Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, et al. RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans. Plos One. 4: e8210. PMID 20011587 DOI: 10.1371/Journal.Pone.0008210 |
0.356 |
|
| 2009 |
Muniyappa R, Chen H, Muzumdar RH, Einstein FH, Yan X, Yue LQ, Barzilai N, Quon MJ. Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats. American Journal of Physiology. Endocrinology and Metabolism. 297: E1023-9. PMID 19706785 DOI: 10.1152/Ajpendo.00397.2009 |
0.422 |
|
| 2009 |
Muzumdar RH, Huffman DM, Atzmon G, Buettner C, Cobb LJ, Fishman S, Budagov T, Cui L, Einstein FH, Poduval A, Hwang D, Barzilai N, Cohen P. Humanin: a novel central regulator of peripheral insulin action. Plos One. 4: e6334. PMID 19623253 DOI: 10.1371/Journal.Pone.0006334 |
0.427 |
|
| 2009 |
Pawlikowska L, Hu D, Huntsman S, Sung A, Chu C, Chen J, Joyner AH, Schork NJ, Hsueh WC, Reiner AP, Psaty BM, Atzmon G, Barzilai N, Cummings SR, Browner WS, et al. Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell. 8: 460-72. PMID 19489743 DOI: 10.1111/J.1474-9726.2009.00493.X |
0.381 |
|
| 2009 |
Huffman DM, Barzilai N. Role of visceral adipose tissue in aging. Biochimica Et Biophysica Acta. 1790: 1117-23. PMID 19364483 DOI: 10.1016/J.Bbagen.2009.01.008 |
0.404 |
|
| 2009 |
Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR, Kooperberg C, LaCroix A, Tracy RP, Atzmon G, Lange EM, et al. Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults. Experimental Gerontology. 44: 350-5. PMID 19249341 DOI: 10.1016/J.Exger.2009.02.004 |
0.302 |
|
| 2009 |
Barzilai N, Bartke A. Biological approaches to mechanistically understand the healthy life span extension achieved by calorie restriction and modulation of hormones. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 187-91. PMID 19228789 DOI: 10.1093/Gerona/Gln061 |
0.314 |
|
| 2009 |
Barzilai N, Muzumdar R, Cohen P. Central regulation of peripheral insulin action Experimental Gerontology. 44: 123. DOI: 10.1016/J.Exger.2008.08.010 |
0.389 |
|
| 2009 |
Heo H, Donepudi R, Madankumar R, Huffman DM, Muzumdar R, Barzilai N, Einstein FH. 233: Hexosamine biosynthetic pathway: does it contribute to insulin resistance of pregnancy? American Journal of Obstetrics and Gynecology. 201: S97. DOI: 10.1016/J.Ajog.2009.10.248 |
0.357 |
|
| 2008 |
Einstein FH, Fishman S, Bauman J, Thompson RF, Huffman DM, Atzmon G, Barzilai N, Muzumdar RH. Enhanced activation of a "nutrient-sensing" pathway with age contributes to insulin resistance. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3450-7. PMID 18566293 DOI: 10.1096/Fj.08-109041 |
0.699 |
|
| 2008 |
Atzmon G, Pollin TI, Crandall J, Tanner K, Schechter CB, Scherer PE, Rincon M, Siegel G, Katz M, Lipton RB, Shuldiner AR, Barzilai N. Adiponectin levels and genotype: a potential regulator of life span in humans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 63: 447-53. PMID 18511746 DOI: 10.1093/Gerona/63.5.447 |
0.351 |
|
| 2008 |
Muzumdar R, Allison DB, Huffman DM, Ma X, Atzmon G, Einstein FH, Fishman S, Poduval AD, McVei T, Keith SW, Barzilai N. Visceral adipose tissue modulates mammalian longevity. Aging Cell. 7: 438-40. PMID 18363902 DOI: 10.1111/J.1474-9726.2008.00391.X |
0.364 |
|
| 2008 |
Suh Y, Atzmon G, Cho MO, Hwang D, Liu B, Leahy DJ, Barzilai N, Cohen P. Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proceedings of the National Academy of Sciences of the United States of America. 105: 3438-42. PMID 18316725 DOI: 10.1073/Pnas.0705467105 |
0.396 |
|
| 2008 |
Einstein FH, Fishman S, Muzumdar RH, Yang XM, Atzmon G, Barzilai N. Accretion of visceral fat and hepatic insulin resistance in pregnant rats. American Journal of Physiology. Endocrinology and Metabolism. 294: E451-5. PMID 18073320 DOI: 10.1152/Ajpendo.00570.2007 |
0.397 |
|
| 2008 |
Barzilai N. Abstract ED04-02: The role of genes in protecting against age-related disease in cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Ed04-02 |
0.383 |
|
| 2008 |
Einstein F, Heo H, Cui L, Huffman DM, Muzumdar RH, Barzilai N. 717: Physiological insulin resistance of pregnancy leads to increased glucose uptake rat pups American Journal of Obstetrics and Gynecology. 199: S205. DOI: 10.1016/J.Ajog.2008.09.748 |
0.398 |
|
| 2008 |
Einstein F, Thompson RF, Heo H, Budagov T, Atzmon G, Goffman D, Barzilai N, Montagna C, Greally JM. 600: Abnormal intrauterine growth induces global epigenetic changes in human stem cells American Journal of Obstetrics and Gynecology. 199: S173. DOI: 10.1016/J.Ajog.2008.09.630 |
0.649 |
|
| 2008 |
Heo H, Cui L, Muzumdar RH, Huffman DM, Barzilai N, Einstein F. 539: Hepatic and peripheral insulin resistance of pregnancy are not reversed in early postpartum rats American Journal of Obstetrics and Gynecology. 199: S158. DOI: 10.1016/J.Ajog.2008.09.569 |
0.349 |
|
| 2007 |
Hwang JH, Stein DT, Barzilai N, Cui MH, Tonelli J, Kishore P, Hawkins M. Increased intrahepatic triglyceride is associated with peripheral insulin resistance: in vivo MR imaging and spectroscopy studies. American Journal of Physiology. Endocrinology and Metabolism. 293: E1663-9. PMID 17911339 DOI: 10.1152/Ajpendo.00590.2006 |
0.65 |
|
| 2007 |
Bergman A, Atzmon G, Ye K, MacCarthy T, Barzilai N. Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging. Plos Computational Biology. 3: e170. PMID 17784782 DOI: 10.1371/Journal.Pcbi.0030170 |
0.366 |
|
| 2007 |
Martin GM, Bergman A, Barzilai N. Genetic determinants of human health span and life span: progress and new opportunities. Plos Genetics. 3: e125. PMID 17677003 DOI: 10.1371/Journal.Pgen.0030125 |
0.331 |
|
| 2007 |
Kim HS, Ali O, Shim M, Lee KW, Vuguin P, Muzumdar R, Barzilai N, Cohen P. Insulin-like growth factor binding protein-3 induces insulin resistance in adipocytes in vitro and in rats in vivo. Pediatric Research. 61: 159-64. PMID 17237715 DOI: 10.1203/Pdr.0B013E31802D8A30 |
0.424 |
|
| 2007 |
Fishman S, Muzumdar RH, Atzmon G, Ma X, Yang X, Einstein FH, Barzilai N. Resistance to leptin action is the major determinant of hepatic triglyceride accumulation in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 53-60. PMID 17099068 DOI: 10.1096/Fj.06-6557Com |
0.404 |
|
| 2007 |
Einstein FH, Lo LW, Muzumdar RH, Fishman S, Atzmon G, Barzilai N. 43: Recurrent pregnancy is associated with visceral adiposity and insulin resistance, but not beta-cell dysfunction in a rodent model American Journal of Obstetrics and Gynecology. 197: S19. DOI: 10.1016/J.Ajog.2007.10.048 |
0.338 |
|
| 2006 |
Muzumdar RH, Ma X, Fishman S, Yang X, Atzmon G, Vuguin P, Einstein FH, Hwang D, Cohen P, Barzilai N. Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action. Diabetes. 55: 2788-96. PMID 17003344 DOI: 10.2337/Db06-0318 |
0.419 |
|
| 2006 |
Atzmon G, Rincon M, Schechter CB, Shuldiner AR, Lipton RB, Bergman A, Barzilai N. Lipoprotein genotype and conserved pathway for exceptional longevity in humans. Plos Biology. 4: e113. PMID 16602826 DOI: 10.1371/Journal.Pbio.0040113 |
0.393 |
|
| 2006 |
Muzumdar RH, Ma X, Yang X, Atzmon G, Barzilai N. Central resistance to the inhibitory effects of leptin on stimulated insulin secretion with aging. Neurobiology of Aging. 27: 1308-14. PMID 16122839 DOI: 10.1016/J.Neurobiolaging.2005.07.007 |
0.443 |
|
| 2006 |
Muzumdar R, Ma X, Yang X, Atzmon G, Cohen P, Barzilai N. OR13-4 DIRECT, CENTRAL, AND OPPOSING EFFECTS OF IGF-1 AND IGFBP-3 ON SYSTEMIC INSULIN ACTION Growth Hormone & Igf Research. 16: S25. DOI: 10.1016/S1096-6374(07)70260-5 |
0.363 |
|
| 2006 |
Einstein F, Fishman S, Muzumdar R, Yang XM, Atzmon G, Merkatz I, Barzilai N. Pregnancy alters adipose biology and its conribution to thrombosis, insulin action and inflammation American Journal of Obstetrics and Gynecology. 195: S152. DOI: 10.1016/J.Ajog.2006.10.537 |
0.368 |
|
| 2006 |
Einstein F, Fishman S, Muzumdar R, Yang XM, Atzmon G, Merkatz I, Barzilai N. Increased hepatic insulin resistance is detemined by visceral fat accretion and accumulation of hepatic triglycerides during pregnancy American Journal of Obstetrics and Gynecology. 195: S152. DOI: 10.1016/J.Ajog.2006.10.536 |
0.356 |
|
| 2005 |
Rincon M, Rudin E, Barzilai N. The insulin/IGF-1 signaling in mammals and its relevance to human longevity. Experimental Gerontology. 40: 873-7. PMID 16168602 DOI: 10.1016/J.Exger.2005.06.014 |
0.411 |
|
| 2005 |
Einstein FH, Atzmon G, Yang XM, Ma XH, Rincon M, Rudin E, Muzumdar R, Barzilai N. Differential responses of visceral and subcutaneous fat depots to nutrients. Diabetes. 54: 672-8. PMID 15734842 DOI: 10.2337/Diabetes.54.3.672 |
0.37 |
|
| 2005 |
Rudin E, Barzilai N. Inflammatory peptides derived from adipose tissue. Immunity & Ageing : I & A. 2: 1. PMID 15679897 DOI: 10.1186/1742-4933-2-1 |
0.339 |
|
| 2005 |
Arking DE, Atzmon G, Arking A, Barzilai N, Dietz HC. Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity. Circulation Research. 96: 412-8. PMID 15677572 DOI: 10.1161/01.Res.0000157171.04054.30 |
0.305 |
|
| 2005 |
Atzmon G, Rincon M, Rabizadeh P, Barzilai N. Biological evidence for inheritance of exceptional longevity. Mechanisms of Ageing and Development. 126: 341-5. PMID 15621216 DOI: 10.1016/J.Mad.2004.08.026 |
0.348 |
|
| 2005 |
Globerson A, Barzilai N. The voyage to healthy longevity: from experimental models to the ultimate goal. Mechanisms of Ageing and Development. 126: 225-9. PMID 15621200 DOI: 10.1016/J.Mad.2004.08.013 |
0.309 |
|
| 2005 |
Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B, Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, et al. The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. The Journal of Biological Chemistry. 280: 4617-26. PMID 15536073 DOI: 10.1074/Jbc.M411863200 |
0.652 |
|
| 2005 |
Rincon M, Muzumdar R, Atzmon G, Barzilai N. The paradox of the insulin/IGF-1 signaling pathway in longevity. Mechanisms of Ageing and Development. 125: 397-403. PMID 15272501 DOI: 10.1016/J.Mad.2004.03.006 |
0.418 |
|
| 2005 |
Einstein FH, Ma XH, Yang XM, Eric R, Muzumdar R, Merkatz IR, Barzilai N. Role of visceral fat in insulin resistance of pregnancy American Journal of Obstetrics and Gynecology. 193: S9. DOI: 10.1016/J.Ajog.2005.10.022 |
0.356 |
|
| 2004 |
Vuguin P, Raab E, Liu B, Barzilai N, Simmons R. Hepatic insulin resistance precedes the development of diabetes in a model of intrauterine growth retardation. Diabetes. 53: 2617-22. PMID 15448092 DOI: 10.2337/Diabetes.53.10.2617 |
0.45 |
|
| 2004 |
Barzilai N, Rossetti L, Lipton RB. Einstein's Institute for Aging Research: collaborative and programmatic approaches in the search for successful aging. Experimental Gerontology. 39: 151-7. PMID 15036407 DOI: 10.1016/J.Exger.2003.10.009 |
0.314 |
|
| 2004 |
Das M, Gabriely I, Barzilai N. Caloric restriction, body fat and ageing in experimental models. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 5: 13-9. PMID 14969503 DOI: 10.1111/J.1467-789X.2004.00115.X |
0.401 |
|
| 2004 |
Muzumdar R, Ma X, Atzmon G, Vuguin P, Yang X, Barzilai N. Decrease in glucose-stimulated insulin secretion with aging is independent of insulin action. Diabetes. 53: 441-6. PMID 14747296 DOI: 10.2337/Diabetes.53.2.441 |
0.469 |
|
| 2004 |
Atzmon G, Schechter C, Greiner W, Davidson D, Rennert G, Barzilai N. Clinical phenotype of families with longevity. Journal of the American Geriatrics Society. 52: 274-7. PMID 14728640 DOI: 10.1111/J.1532-5415.2004.52068.X |
0.314 |
|
| 2003 |
Atwood CS, Barzilai N, Bowen RL, Brown-Borg HM, Jarrard DF, Fu VX, Heilbronn LK, Ingram DK, Ravussin E, Schwartz RS, Weindruch R. Pennington scientific symposium on mechanisms and retardation of aging. Experimental Gerontology. 38: 1217-26. PMID 14580876 DOI: 10.1016/J.Exger.2003.08.005 |
0.353 |
|
| 2003 |
Barzilai N, Atzmon G, Schechter C, Schaefer EJ, Cupples AL, Lipton R, Cheng S, Shuldiner AR. Unique lipoprotein phenotype and genotype associated with exceptional longevity. Jama. 290: 2030-40. PMID 14559957 DOI: 10.1016/J.Accreview.2003.12.029 |
0.328 |
|
| 2003 |
Gabriely I, Barzilai N. Surgical removal of visceral adipose tissue: effects on insulin action. Current Diabetes Reports. 3: 201-6. PMID 12762966 DOI: 10.1007/S11892-003-0064-3 |
0.435 |
|
| 2003 |
Muzumdar R, Ma X, Yang X, Atzmon G, Bernstein J, Karkanias G, Barzilai N. Physiologic effect of leptin on insulin secretion is mediated mainly through central mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1130-2. PMID 12709405 DOI: 10.1096/Fj.02-0991Fje |
0.423 |
|
| 2003 |
Ma X, Muzumdar R, Gabriely I, Atzmon G, Barzilai N. Does the brain lead the metabolic decline in aging? Clinical Neuroscience Research. 2: 339-344. DOI: 10.1016/S1566-2772(03)00011-2 |
0.433 |
|
| 2002 |
Gabriely I, Ma XH, Yang XM, Atzmon G, Rajala MW, Berg AH, Scherer P, Rossetti L, Barzilai N. Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process? Diabetes. 51: 2951-8. PMID 12351432 DOI: 10.2337/Diabetes.51.10.2951 |
0.466 |
|
| 2002 |
Rajala MW, Lin Y, Ranalletta M, Yang XM, Qian H, Gingerich R, Barzilai N, Scherer PE. Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-alpha in adipose tissue. Molecular Endocrinology (Baltimore, Md.). 16: 1920-30. PMID 12145345 DOI: 10.1210/Me.2002-0048 |
0.338 |
|
| 2002 |
Ma XH, Muzumdar R, Yang XM, Gabriely I, Berger R, Barzilai N. Aging is associated with resistance to effects of leptin on fat distribution and insulin action. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 57: B225-31. PMID 12023258 DOI: 10.1093/Gerona/57.6.B225 |
0.445 |
|
| 2002 |
Gabriely I, Ma XH, Yang XM, Rossetti L, Barzilai N. Leptin resistance during aging is independent of fat mass. Diabetes. 51: 1016-21. PMID 11916920 DOI: 10.2337/Diabetes.51.4.1016 |
0.41 |
|
| 2002 |
Gabriely I, Yang XM, Cases JA, Ma XH, Rossetti L, Barzilai N. Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway. Atherosclerosis. 160: 115-22. PMID 11755928 DOI: 10.1016/S0021-9150(01)00574-3 |
0.386 |
|
| 2001 |
Wang J, Obici S, Morgan K, Barzilai N, Feng Z, Rossetti L. Overfeeding rapidly induces leptin and insulin resistance. Diabetes. 50: 2786-91. PMID 11723062 DOI: 10.2337/Diabetes.50.12.2786 |
0.426 |
|
| 2001 |
Lin Y, Rajala MW, Berger JP, Moller DE, Barzilai N, Scherer PE. Hyperglycemia-induced production of acute phase reactants in adipose tissue. The Journal of Biological Chemistry. 276: 42077-83. PMID 11546817 DOI: 10.1074/Jbc.M107101200 |
0.314 |
|
| 2001 |
Gabriely I, Barzilai N. The role of fat cell derived peptides in age-related metabolic alterations. Mechanisms of Ageing and Development. 122: 1565-76. PMID 11511397 DOI: 10.1016/S0047-6374(01)00287-1 |
0.353 |
|
| 2001 |
Gabriely I, Yang XM, Cases JA, Ma XH, Rossetti L, Barzilai N. Hyperglycemia modulates angiotensinogen gene expression. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 281: R795-802. PMID 11506994 DOI: 10.1152/Ajpregu.2001.281.3.R795 |
0.413 |
|
| 2001 |
Cases JA, Gabriely I, Ma XH, Yang XM, Michaeli T, Fleischer N, Rossetti L, Barzilai N. Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo. Diabetes. 50: 348-52. PMID 11272146 DOI: 10.2337/Diabetes.50.2.348 |
0.429 |
|
| 2001 |
Vuguin P, Ma X, Yang X, Surana M, Liu B, Barzilai N. Food deprivation limits insulin secretory capacity in postpubertal rats. Pediatric Research. 49: 468-73. PMID 11264428 DOI: 10.1203/00006450-200104000-00006 |
0.418 |
|
| 2001 |
Barzilai N, Gabriely I. The role of fat depletion in the biological benefits of caloric restriction. The Journal of Nutrition. 131: 903S-906S. PMID 11238783 DOI: 10.1093/Jn/131.3.903S |
0.339 |
|
| 2001 |
Barzilai N, Shuldiner AR. Searching for human longevity genes: the future history of gerontology in the post-genomic era. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 56: M83-7. PMID 11213281 DOI: 10.1093/Gerona/56.2.M83 |
0.31 |
|
| 2001 |
Cases JA, Barzilai N. The regulation of body fat distribution and the modulation of insulin action. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. S63-6. PMID 11126245 DOI: 10.1038/Sj.Ijo.0801508 |
0.423 |
|
| 2000 |
Barzilai N, Gupta G. Interaction between aging and syndrome X: new insights on the pathophysiology of fat distribution. Annals of the New York Academy of Sciences. 892: 58-72. PMID 10842652 DOI: 10.1111/J.1749-6632.1999.Tb07785.X |
0.465 |
|
| 2000 |
Gupta G, Cases JA, She L, Ma XH, Yang XM, Hu M, Wu J, Rossetti L, Barzilai N. Ability of insulin to modulate hepatic glucose production in aging rats is impaired by fat accumulation. American Journal of Physiology. Endocrinology and Metabolism. 278: E985-91. PMID 10826999 DOI: 10.1152/Ajpendo.2000.278.6.E985 |
0.42 |
|
| 2000 |
Gupta G, She L, Ma XH, Yang XM, Hu M, Cases JA, Vuguin P, Rossetti L, Barzilai N. Aging does not contribute to the decline in insulin action on storage of muscle glycogen in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R111-7. PMID 10644628 DOI: 10.1152/Ajpregu.2000.278.1.R111 |
0.416 |
|
| 1999 |
Hawkins M, Hu M, Yu J, Eder H, Vuguin P, She L, Barzilai N, Leiser M, Backer JM, Rossetti L. Discordant effects of glucosamine on insulin-stimulated glucose metabolism and phosphatidylinositol 3-kinase activity Journal of Biological Chemistry. 274: 31312-31319. PMID 10531330 DOI: 10.1074/Jbc.274.44.31312 |
0.673 |
|
| 1999 |
Barzilai N, She L, Liu L, Wang J, Hu M, Vuguin P, Rossetti L. Decreased visceral adiposity accounts for leptin effect on hepatic but not peripheral insulin action. The American Journal of Physiology. 277: E291-8. PMID 10444425 DOI: 10.1152/Ajpendo.1999.277.2.E291 |
0.405 |
|
| 1999 |
Wang J, Liu R, Liu L, Chowdhury R, Barzilai N, Tan J, Rossetti L. The effect of leptin on Lep expression is tissue-specific and nutritionally regulated. Nature Medicine. 5: 895-9. PMID 10426312 DOI: 10.1038/11335 |
0.315 |
|
| 1999 |
Barzilai N, Gupta G. Revisiting the role of fat mass in the life extension induced by caloric restriction. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 54: B89-96; discussion B. PMID 10191831 DOI: 10.1093/Gerona/54.3.B89 |
0.388 |
|
| 1999 |
Barzilai N, She L, Liu BQ, Vuguin P, Cohen P, Wang J, Rossetti L. Surgical removal of visceral fat reverses hepatic insulin resistance. Diabetes. 48: 94-8. PMID 9892227 DOI: 10.2337/Diabetes.48.1.94 |
0.447 |
|
| 1999 |
Vuguin P, She L, Surana N, Liu B, Saenger P, Barzilai N. Marked Increase in the Ability of the β-Cells to Secrete Insulin in Response to Glucose and FFA Occurs Post-Puberty Pediatric Research. 45: 99A-99A. DOI: 10.1203/00006450-199904020-00593 |
0.39 |
|
| 1999 |
Barzilai N. Author's Repsonse to Commentary on "Revisiting the Role of Fat Mass in the Life Extension Induced by Caloric Restriction" The Journals of Gerontology Series a: Biological Sciences and Medical Sciences. 54: B98-B98. DOI: 10.1093/Gerona/54.3.B98 |
0.375 |
|
| 1998 |
Liu L, Karkanias GB, Morales JC, Hawkins M, Barzilai N, Wang J, Rossetti L. Intracerebroventricular leptin regulates hepatic but not peripheral glucose fluxes. The Journal of Biological Chemistry. 273: 31160-7. PMID 9813020 DOI: 10.1074/Jbc.273.47.31160 |
0.666 |
|
| 1998 |
Wang J, Liu R, Hawkins M, Barzilai N, Rossetti L. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature. 393: 684-8. PMID 9641678 DOI: 10.1038/31474 |
0.625 |
|
| 1998 |
Barzilai N, Banerjee S, Hawkins M, Chen W, Rossetti L. Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. The Journal of Clinical Investigation. 101: 1353-61. PMID 9525977 DOI: 10.1172/Jci485 |
0.683 |
|
| 1998 |
Barzilai N, Banerjee S, Hawkins M, Chang CJ, Chen W, Rossetti L. The effect of age-dependent increase in fat mass on peripheral insulin action is saturable. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 53: B141-6. PMID 9520910 DOI: 10.1093/Gerona/53A.2.B141 |
0.694 |
|
| 1998 |
Massillon D, Chen W, Barzilai N, Prus-Wertheimer D, Hawkins M, Liu R, Taub R, Rossetti L. Carbon flux via the pentose phosphate pathway regulates the hepatic expression of the glucose-6-phosphatase and phosphoenolpyruvate carboxykinase genes in conscious rats. The Journal of Biological Chemistry. 273: 228-34. PMID 9417069 DOI: 10.1074/Jbc.273.1.228 |
0.613 |
|
| 1998 |
Barzilai N, Wang J, Massilon D, Vuguin P, Hawkins M, Rossetti L. Leptin selectively decreases visceral adiposity and enhances insulin action. The Journal of Clinical Investigation. 100: 3105-10. PMID 9399957 DOI: 10.1172/Jci119865 |
0.682 |
|
| 1997 |
Banerjee S, Saenger P, Hu M, Chen W, Barzilai N. Fat accretion and the regulation of insulin-mediated glycogen synthesis after puberty in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 273: R1534-R1539. PMID 29586743 DOI: 10.1152/Ajpregu.1997.273.4.R1534 |
0.412 |
|
| 1997 |
Rossetti L, Chen W, Hu M, Hawkins M, Barzilai N, Efrat S. Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele. American Journal of Physiology. Endocrinology and Metabolism. 273: E743-E750. PMID 29585232 DOI: 10.1152/Ajpendo.1997.273.4.E743 |
0.653 |
|
| 1997 |
Rossetti L, Massillon D, Barzilai N, Vuguin P, Chen W, Hawkins M, Wu J, Wang J. Short term effects of leptin on hepatic gluconeogenesis and in vivo insulin action. The Journal of Biological Chemistry. 272: 27758-63. PMID 9346919 DOI: 10.1074/Jbc.272.44.27758 |
0.681 |
|
| 1997 |
Rossetti L, Stenbit AE, Chen W, Hu M, Barzilai N, Katz EB, Charron MJ. Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene Journal of Clinical Investigation. 100: 1831-1839. PMID 9312184 DOI: 10.1172/Jci119711 |
0.419 |
|
| 1997 |
Hawkins M, Barzilai N, Liu R, Hu M, Chen W, Rossetti L. Role of the glucosamine pathway in fat-induced insulin resistance. The Journal of Clinical Investigation. 99: 2173-82. PMID 9151789 DOI: 10.1172/Jci119390 |
0.667 |
|
| 1997 |
Raghavan S, Saenger P, Hu M, Barzilai N. Intracellular pathways of insulin-mediated glucose uptake before and after puberty in conscious rats. Pediatric Research. 41: 340-5. PMID 9078532 DOI: 10.1203/00006450-199703000-00006 |
0.438 |
|
| 1997 |
Hawkins M, Angelov I, Liu R, Barzilai N, Rossetti L. The tissue concentration of UDP-N-acetylglucosamine modulates the stimulatory effect of insulin on skeletal muscle glucose uptake. The Journal of Biological Chemistry. 272: 4889-95. PMID 9030547 DOI: 10.1074/Jbc.272.8.4889 |
0.661 |
|
| 1997 |
Massillon D, Barzilai N, Hawkins M, Prus-Wertheimer D, Rossetti L. Induction of hepatic glucose-6-phosphatase gene expression by lipid infusion. Diabetes. 46: 153-7. PMID 8971097 DOI: 10.2337/Diab.46.1.153 |
0.665 |
|
| 1997 |
Banerjee S, Saenger P, Chen W, Rossetti L, Barzilai N. Prevention of Fat Accretion through Puberty restores Insulin Action on Glycogen Synthesis to Prepubertal Levels in Conscious Rats. † 373 Pediatric Research. 41: 65-65. DOI: 10.1203/00006450-199704001-00393 |
0.386 |
|
| 1996 |
Hawkins M, Barzilai N, Chen W, Angelov I, Hu M, Cohen P, Rossetti L. Increased hexosamine availability similarly impairs the action of insulin and IGF-1 on glucose disposal. Diabetes. 45: 1734-43. PMID 8922359 DOI: 10.2337/Diab.45.12.1734 |
0.669 |
|
| 1996 |
Barzilai N, Hawkins M, Angelov I, Hu M, Rossetti L. Glucosamine-induced inhibition of liver glucokinase impairs the ability of hyperglycemia to suppress endogenous glucose production. Diabetes. 45: 1329-35. PMID 8826967 DOI: 10.2337/Diab.45.10.1329 |
0.654 |
|
| 1996 |
Barzilai N, Rossetti L. Age-related changes in body composition are associated with hepatic insulin resistance in conscious rats. The American Journal of Physiology. 270: E930-6. PMID 8764175 DOI: 10.1152/Ajpendo.1996.270.6.E930 |
0.462 |
|
| 1996 |
Barzilai N, Groop PH, Groop L, DeFronzo RA. A novel mechanism of glipizide sulfonylurea action: decreased metabolic clearance rate of insulin. Acta Diabetologica. 32: 273-8. PMID 8750768 DOI: 10.1007/Bf00576262 |
0.421 |
|
| 1996 |
Massillon D, Barzilai N, Chen W, Hu M, Rossetti L. Glucose regulates in vivo glucose-6-phosphatase gene expression in the liver of diabetic rats. The Journal of Biological Chemistry. 271: 9871-4. PMID 8626617 DOI: 10.1074/Jbc.271.17.9871 |
0.408 |
|
| 1996 |
Massillon D, Chen W, Hawkins M, Liu R, Barzilai N, Rossetti L. Quantitation of hepatic glucose fluxes and pathways of hepatic glycogen synthesis in conscious mice. The American Journal of Physiology. 269: E1037-43. PMID 8572194 DOI: 10.1152/Ajpendo.1995.269.6.E1037 |
0.636 |
|
| 1996 |
Rossetti L, Barzilai N, Chen W, Harris T, Yang D, Rogler CE. Hepatic overexpression of insulin-like growth factor-II in adulthood increases basal and insulin-stimulated glucose disposal in conscious mice. The Journal of Biological Chemistry. 271: 203-8. PMID 8550560 DOI: 10.1074/Jbc.271.1.203 |
0.417 |
|
| 1995 |
Bali D, Svetlanov A, Lee HW, Fusco-DeMane D, Leiser M, Li B, Barzilai N, Surana M, Hou H, Fleischer N, DePinho R, Rossetti L, Efrat S. Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene Journal of Biological Chemistry. 270: 21464-21467. PMID 7665557 DOI: 10.1074/Jbc.270.37.21464 |
0.423 |
|
| 1995 |
Rossetti L, Hawkins M, Chen W, Gindi J, Barzilai N. In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats. The Journal of Clinical Investigation. 96: 132-40. PMID 7615783 DOI: 10.1172/Jci118013 |
0.667 |
|
| 1995 |
Barzilai N, Massillon D, Rossetti L. Effects of fasting on hepatic and peripheral glucose metabolism in conscious rats with near-total fat depletion. The Biochemical Journal. 819-26. PMID 7575414 DOI: 10.1042/Bj3100819 |
0.416 |
|
| 1995 |
Barzilai N, Rossetti L. Relationship between changes in body composition and insulin responsiveness in models of the aging rat. The American Journal of Physiology. 269: E591-7. PMID 7573438 DOI: 10.1152/Ajpendo.1995.269.3.E591 |
0.455 |
|
| 1993 |
Rossetti L, Giaccari A, Barzilai N, Howard K, Sebel G, Hu M. Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes. The Journal of Clinical Investigation. 92: 1126-34. PMID 8397219 DOI: 10.1172/Jci116681 |
0.387 |
|
| 1992 |
DeFronzo RA, Barzilai N, Simonson DC. Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects. The Journal of Clinical Endocrinology and Metabolism. 73: 1294-301. PMID 1955512 DOI: 10.1210/jcem-73-6-1294 |
0.301 |
|
| 1992 |
Barzilai N, Cohen P, Karnieli E, Enat R, Epstein O, Owen J, McIntyre N. In vivo insulin action in hepatocellular and cholestatic liver cirrhosis. Journal of Endocrinological Investigation. 14: 727-35. PMID 1761807 DOI: 10.1007/BF03347904 |
0.321 |
|
| 1991 |
Groop LC, Barzilai N, Ratheiser K, Luzi L, Wåhlin-Boll E, Melander A, DeFronzo RA. Dose-dependent effects of glyburide on insulin secretion and glucose uptake in humans. Diabetes Care. 14: 724-7. PMID 1954808 DOI: 10.2337/Diacare.14.8.724 |
0.411 |
|
| 1991 |
Barzilai N, Cohen P, Bar-Illan R, McIntyre N, Karnieli E. Case report: increased insulin sensitivity in tumor hypoglycemia in a diabetic patient: glucose metabolism in tumor hypoglycemia. The American Journal of the Medical Sciences. 302: 229-34. PMID 1656753 DOI: 10.1097/00000441-199110000-00007 |
0.313 |
|
| 1990 |
Cohen P, Harel C, Bergman R, Daoud D, Pam Z, Barzilai N, Armoni M, Karnieli E. Insulin resistance and acanthosis nigricans: evidence for a postbinding defect in vivo. Metabolism: Clinical and Experimental. 39: 1006-11. PMID 2215248 DOI: 10.1016/0026-0495(90)90158-9 |
0.315 |
|
| 1989 |
Barzilai N, Stessman J, Cohen P, Morali G, Barzilai D, Karnieli E. Glucoregulatory hormone influence on hepatic glucose production in the elderly Age. 12: 13-17. DOI: 10.1007/Bf02432513 |
0.341 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2016 |
Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF, Chasman DI, Nolte IM, Tragante V, van der Laan SW, Perry JR, Kong A, ... ... Barzilai N, et al. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nature Genetics. PMID 27798627 DOI: 10.1038/Ng.3698 |
0.299 |
|
| 2009 |
Lipton RB, Sanders AE, Ozelius L, Katz M, Derby CA, Atzmon G, Wang C, Barzilai N. P4-134: Longevity genotype is associated with a reduced rate of memory decline and reduced incidence of dementia: Results from the Einstein Aging Study Alzheimer's & Dementia. 5: P471-P471. DOI: 10.1016/J.Jalz.2009.04.802 |
0.299 |
|
| 1986 |
Cohen P, Barzilai N, Barzilai D, Karnieli E. Correlation between insulin clearance and insulin responsiveness: studies in normal, obese, hyperthyroid, and Cushing's syndrome patients. Metabolism: Clinical and Experimental. 35: 744-9. PMID 3526086 DOI: 10.1016/0026-0495(86)90242-8 |
0.299 |
|
| 2016 |
Burd CE, Gill MS, Niedernhofer LJ, Robbins PD, Austad SN, Barzilai N, Kirkland JL. Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27535964 DOI: 10.1093/Gerona/Glw112 |
0.298 |
|
| 2017 |
Raz Y, Guerrero-Ros I, Maier A, Slagboom PE, Atzmon G, Barzilai N, Macian F. Activation-Induced Autophagy Is Preserved in CD4+ T-Cells in Familial Longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28486590 DOI: 10.1093/Gerona/Glx020 |
0.297 |
|
| 2017 |
Bae H, Gurinovich A, Malovini A, Atzmon G, Andersen SL, Villa F, Barzilai N, Puca A, Perls TT, Sebastiani P. Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28977569 DOI: 10.1093/Gerona/Glx124 |
0.296 |
|
| 1985 |
Karnieli E, Cohen P, Barzilai N, Ish-Shalom Z, Armoni M, Rafaelov R, Barzilai D. Insulin resistance in Cushing's syndrome. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 17: 518-21. PMID 3905556 DOI: 10.1055/s-2007-1013593 |
0.296 |
|
| 2012 |
Barzilai N, Rennert G. The rationale for delaying aging and the prevention of age-related diseases. Rambam Maimonides Medical Journal. 3: e0020. PMID 23908844 DOI: 10.5041/Rmmj.10087 |
0.292 |
|
| 1999 |
Barzilai N. The Pathophysiology of Diabetes in Aging Journal of Geriatric Drug Therapy. 12: 5-19. DOI: 10.1300/J089V12N02_04 |
0.292 |
|
| 2017 |
Espeland MA, Crimmins EM, Grossardt BR, Crandall JP, Gelfond JA, Harris TB, Kritchevsky SB, Manson JE, Robinson JG, Rocca WA, Temprosa M, Thomas F, Wallace R, Barzilai N. Clinical Trials Targeting Aging and Age-Related Multimorbidity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 72: 355-361. PMID 28364543 DOI: 10.1093/Gerona/Glw220 |
0.292 |
|
| 1986 |
Cohen P, Barzilai N, Bar-Ilan R, Yassin K, Karnieli E. Lack of suppression of insulin secretion by hyperinsulinemia in a patient with an insulinoma. The Journal of Clinical Endocrinology and Metabolism. 63: 1411-3. PMID 3023422 DOI: 10.1210/jcem-63-6-1411 |
0.291 |
|
| 1991 |
Cohen P, Barzilai N, Lerman A, Harel H, Szylman P, Karnieli E. Insulin effects on glucose and potassium metabolism in vivo: evidence for selective insulin resistance in humans. The Journal of Clinical Endocrinology and Metabolism. 73: 564-8. PMID 1874934 DOI: 10.1210/jcem-73-3-564 |
0.29 |
|
| 2016 |
Ismail K, Nussbaum L, Sebastiani P, Andersen S, Perls T, Barzilai N, Milman S. Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity. Journal of the American Geriatrics Society. PMID 27377170 DOI: 10.1111/Jgs.14222 |
0.29 |
|
| 2016 |
Newman JC, Milman S, Hashmi SK, Austad SN, Kirkland JL, Halter JB, Barzilai N. Strategies and Challenges in Clinical Trials Targeting Human Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27535968 DOI: 10.1093/Gerona/Glw149 |
0.289 |
|
| 2021 |
Quipildor GF, Mao K, Beltran PJ, Barzilai N, Huffman DM. Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons. Diabetes. PMID 34285117 DOI: 10.2337/db21-0028 |
0.289 |
|
| 2012 |
Lipton R, Wang C, Katz M, Zimmerman M, Derby C, Verghese J, Sanders A, Ozelius L, Barzilai N. P4-081: Genetic variability in the cholesteryl ester transfer protein (CETP) gene may buffer the effect of APOE-ε4 on incidence of amnestic mild cognitive impairment (aMCI): Results for the Einstein Aging Study (EAS) Alzheimer's & Dementia. 8: P662-P662. DOI: 10.1016/J.Jalz.2012.05.1783 |
0.288 |
|
| 2017 |
Sebastiani P, Gurinovich A, Bae H, Andersen S, Malovini A, Atzmon G, Villa F, Kraja AT, Ben-Avraham D, Barzilai N, Puca A, Perls TT. Four Genome-Wide Association Studies Identify New Extreme Longevity Variants. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28329165 DOI: 10.1093/Gerona/Glx027 |
0.284 |
|
| 2009 |
Atzmon G, Barzilai N, Hollowell JG, Surks MI, Gabriely I. Extreme longevity is associated with increased serum thyrotropin. The Journal of Clinical Endocrinology and Metabolism. 94: 1251-4. PMID 19158193 DOI: 10.1210/Jc.2008-2325 |
0.283 |
|
| 2017 |
Ayers E, Barzilai N, Crandall JP, Milman S, Verghese J. Association of Family History of Exceptional Longevity With Decline in Physical Function in Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28379407 DOI: 10.1093/Gerona/Glx053 |
0.281 |
|
| 2012 |
Gombar S, Jung HJ, Dong F, Calder B, Atzmon G, Barzilai N, Tian XL, Pothof J, Hoeijmakers JH, Campisi J, Vijg J, Suh Y. Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing. Bmc Genomics. 13: 353. PMID 22846614 DOI: 10.1186/1471-2164-13-353 |
0.279 |
|
| 2018 |
Barzilai N, Cuervo AM, Austad S. Aging as a Biological Target for Prevention and Therapy. Jama. PMID 30242337 DOI: 10.1001/Jama.2018.9562 |
0.278 |
|
| 2001 |
Barzilai N, Gabriely I, Gabriely M, Iankowitz N, Sorkin JD. Offspring of centenarians have a favorable lipid profile. Journal of the American Geriatrics Society. 49: 76-9. PMID 11207846 DOI: 10.1046/J.1532-5415.2001.49013.X |
0.278 |
|
| 2009 |
Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SEJ, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, et al. Correction: RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans Plos One. 4. DOI: 10.1371/Annotation/387F8074-5F80-4Bdd-Bb0B-B36D49A16Ac0 |
0.277 |
|
| 2010 |
Neuman RJ, Wasson J, Atzmon G, Wainstein J, Yerushalmi Y, Cohen J, Barzilai N, Blech I, Glaser B, Permutt MA. Gene-gene interactions lead to higher risk for development of type 2 diabetes in an Ashkenazi Jewish population. Plos One. 5: e9903. PMID 20361036 DOI: 10.1371/Journal.Pone.0009903 |
0.277 |
|
| 2016 |
Freudenberg-Hua Y, Li W, Abhyankar A, Vacic V, Cortes V, Ben-Avraham D, Koppel J, Greenwald B, Germer S, Darnell RB, Barzilai N, Freudenberg J, Atzmon G, Davies P. Differential Burden of Rare Protein Truncating Variants in Alzheimer's Disease Patients Compared to Centenarians. Human Molecular Genetics. PMID 27260402 DOI: 10.1093/Hmg/Ddw150 |
0.276 |
|
| 2021 |
Zhang WB, Ye K, Barzilai N, Milman S. The antagonistic pleiotropy of insulin-like growth factor 1. Aging Cell. e13443. PMID 34363732 DOI: 10.1111/acel.13443 |
0.276 |
|
| 2018 |
Rivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, et al. Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population. Plos Genetics. 14: e1007329. PMID 29795570 DOI: 10.1371/Journal.Pgen.1007329 |
0.273 |
|
| 2016 |
Roshandel D, Klein R, Klein BE, Wolffenbuttel BH, van der Klauw MM, van Vliet-Ostaptchouk JV, Atzmon G, Ben-Avraham D, Crandall JP, Barzilai N, Bull SB, Canty AJ, Hosseini SM, Hiraki LT, Maynard J, et al. A New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes also Associated with Blood and Skin Glycated Proteins. Diabetes. PMID 27207532 DOI: 10.2337/Db15-1484 |
0.273 |
|
| 2003 |
Barzilai N. Discovering the secrets of successful longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 58: 225-6. PMID 12634287 DOI: 10.1093/Gerona/58.3.M225 |
0.273 |
|
| 2003 |
Atzmon G, Yang XM, Muzumdar R, Ma XH, Gabriely I, Barzilai N. Differential gene expression between visceral and subcutaneous fat depots. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 34: 622-8. PMID 12660871 DOI: 10.1055/S-2002-38250 |
0.271 |
|
| 2016 |
Brodaty H, Woolf C, Andersen S, Barzilai N, Brayne C, Cheung KS, Corrada MM, Crawford JD, Daly C, Gondo Y, Hagberg B, Hirose N, Holstege H, Kawas C, Kaye J, et al. ICC-dementia (International Centenarian Consortium - dementia): an international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups. Bmc Neurology. 16: 52. PMID 27098177 DOI: 10.1186/S12883-016-0569-4 |
0.27 |
|
| 2015 |
Govindaraju D, Atzmon G, Barzilai N. Genetics, lifestyle and longevity: Lessons from centenarians. Applied & Translational Genomics. 4: 23-32. PMID 26937346 DOI: 10.1016/J.Atg.2015.01.001 |
0.27 |
|
| 2018 |
Barzilai N. An Update On Anti-Aging Drug Trials Innovation in Aging. 2: 544-544. DOI: 10.1093/Geroni/Igy023.2007 |
0.269 |
|
| 2008 |
Atzmon G, Hwang D, Muzumdar R, Budagov T, Cohen P, Barzilai N. OR6,1 Telomere length is associated with exceptional longevity and is modulated by the IGF system Growth Hormone & Igf Research. 18: S12. DOI: 10.1016/S1096-6374(08)70038-8 |
0.268 |
|
| 2016 |
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, ... ... Barzilai N, et al. The genetic architecture of type 2 diabetes. Nature. PMID 27398621 DOI: 10.1038/Nature18642 |
0.267 |
|
| 2009 |
Crandall JP, Shamoon H, Cohen HW, Reid M, Gajavelli S, Trandafirescu G, Tabatabaie V, Barzilai N. Post-challenge hyperglycemia in older adults is associated with increased cardiovascular risk profile. The Journal of Clinical Endocrinology and Metabolism. 94: 1595-601. PMID 19208733 DOI: 10.1210/Jc.2008-1829 |
0.267 |
|
| 2020 |
Gutman D, Lidzbarsky G, Milman S, Gao T, Sin-Chan P, Gonzaga-Jauregui C, Deelen J, Shuldiner AR, Barzilai N, Atzmon G. Similar burden of pathogenic coding variants in exceptionally long-lived individuals and individuals without exceptional longevity. Aging Cell. e13216. PMID 32860726 DOI: 10.1111/Acel.13216 |
0.267 |
|
| 2019 |
Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW, Fasano A, Miller GW, Miller AH, Mantovani A, Weyand CM, Barzilai N, Goronzy JJ, et al. Chronic inflammation in the etiology of disease across the life span. Nature Medicine. 25: 1822-1832. PMID 31806905 DOI: 10.1038/S41591-019-0675-0 |
0.266 |
|
| 2017 |
Gubbi S, Schwartz E, Crandall J, Verghese J, Holtzer R, Atzmon G, Braunstein R, Barzilai N, Milman S. Effect of Exceptional Parental Longevity and Lifestyle Factors on Prevalence of Cardiovascular Disease in Offspring. The American Journal of Cardiology. PMID 29050682 DOI: 10.1016/J.Amjcard.2017.08.040 |
0.266 |
|
| 2016 |
Ryu S, Atzmon G, Barzilai N, Raghavachari N, Suh Y. Genetic landscape of APOE in human longevity revealed by high-throughput sequencing. Mechanisms of Ageing and Development. PMID 26930295 DOI: 10.1016/J.Mad.2016.02.010 |
0.264 |
|
| 2002 |
Atzmon G, Gabriely I, Greiner W, Davidson D, Schechter C, Barzilai N. Plasma HDL levels highly correlate with cognitive function in exceptional longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 57: M712-5. PMID 12403798 DOI: 10.1093/Gerona/57.11.M712 |
0.264 |
|
| 2017 |
Sathyan S, Barzilai N, Atzmon G, Milman S, Ayers E, Verghese J. Association of anti-inflammatory cytokine IL10 polymorphisms with motoric cognitive risk syndrome in an Ashkenazi Jewish population. Neurobiology of Aging. PMID 28705468 DOI: 10.1016/J.Neurobiolaging.2017.06.006 |
0.262 |
|
| 1993 |
Barzilai N, Karnieli E, Barzilai D, Cohen P. Correlation between glucose disposal and amino acids levels in hyperthyroidism. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 25: 382-5. PMID 8406325 DOI: 10.1055/s-2007-1002124 |
0.261 |
|
| 2012 |
Kenny EE, Pe'er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant SR, Bressman S, Burns ER, et al. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. Plos Genetics. 8: e1002559. PMID 22412388 DOI: 10.1371/Journal.Pgen.1002559 |
0.26 |
|
| 2019 |
Gurinovich A, Andersen SL, Puca A, Atzmon G, Barzilai N, Sebastiani P. Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 74: S45-S51. PMID 31724059 DOI: 10.1093/Gerona/Glz179 |
0.26 |
|
| 2011 |
Karakash S, Heo H, Dar P, Koba W, Fine E, Barzilai N, Einstein F. 377: MicroPET Imaging in pregnancy: a novel way to visualize and quantify in vivo glucose uptake in pregnancy American Journal of Obstetrics and Gynecology. 204: S152-S153. DOI: 10.1016/J.Ajog.2010.10.395 |
0.257 |
|
| 2007 |
Iwata N, Zhang J, Atzmon G, Leanza S, Cho J, Chomyn A, Burk RD, Barzilai N, Attardi G. Aging-related occurrence in Ashkenazi Jews of leukocyte heteroplasmic mtDNA mutation adjacent to replication origin frequently remodeled in Italian centenarians. Mitochondrion. 7: 267-72. PMID 17452024 DOI: 10.1016/J.Mito.2007.03.001 |
0.256 |
|
| 2009 |
Rajpathak SN, Kumbhani DJ, Crandall J, Barzilai N, Alderman M, Ridker PM. Statin therapy and risk of developing type 2 diabetes: a meta-analysis. Diabetes Care. 32: 1924-9. PMID 19794004 DOI: 10.2337/Dc09-0738 |
0.256 |
|
| 2010 |
Sanders AE, Wang C, Katz M, Derby CA, Barzilai N, Ozelius L, Lipton RB. Association of a functional polymorphism in the cholesteryl ester transfer protein (CETP) gene with memory decline and incidence of dementia. Jama. 303: 150-8. PMID 20068209 DOI: 10.1001/Jama.2009.1988 |
0.254 |
|
| 2018 |
Stambler I, Jin K, Lederman S, Barzilai N, Olshansky SJ, Omokaro E, Barratt J, Anisimov VN, Rattan S, Yang S, Forster M, Byles J. Aging Health and R&D for Healthy Longevity Must Be Included into the WHO Work Program. Aging and Disease. 9: 331-333. PMID 29896422 DOI: 10.14336/Ad.2017.1120 |
0.253 |
|
| 2014 |
Freudenberg-Hua Y, Freudenberg J, Vacic V, Abhyankar A, Emde AK, Ben-Avraham D, Barzilai N, Oschwald D, Christen E, Koppel J, Greenwald B, Darnell RB, Germer S, Atzmon G, Davies P. Disease variants in genomes of 44 centenarians. Molecular Genetics & Genomic Medicine. 2: 438-50. PMID 25333069 DOI: 10.1002/Mgg3.86 |
0.252 |
|
| 2014 |
Vacic V, Ozelius LJ, Clark LN, Bar-Shira A, Gana-Weisz M, Gurevich T, Gusev A, Kedmi M, Kenny EE, Liu X, Mejia-Santana H, Mirelman A, Raymond D, Saunders-Pullman R, Desnick RJ, ... ... Barzilai N, et al. Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes. Human Molecular Genetics. 23: 4693-702. PMID 24842889 DOI: 10.1093/Hmg/Ddu158 |
0.252 |
|
| 2017 |
Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Barzilai N, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/Sdata.2017.179 |
0.25 |
|
| 2019 |
Gurinovich A, Bae H, Farrell JJ, Andersen SL, Monti S, Puca A, Atzmon G, Barzilai N, Perls TT, Sebastiani P. PopCluster: an algorithm to identify genetic variants with ethnicity-dependent effects. Bioinformatics (Oxford, England). PMID 30624692 DOI: 10.1093/Bioinformatics/Btz017 |
0.246 |
|
| 2014 |
Gershoni M, Levin L, Ovadia O, Toiw Y, Shani N, Dadon S, Barzilai N, Bergman A, Atzmon G, Wainstein J, Tsur A, Nijtmans L, Glaser B, Mishmar D. Disrupting mitochondrial-nuclear coevolution affects OXPHOS complex I integrity and impacts human health. Genome Biology and Evolution. 6: 2665-80. PMID 25245408 DOI: 10.1093/Gbe/Evu208 |
0.246 |
|
| 2017 |
Freudenberg-Hua Y, Li W, Ben-Avraham D, Koppel J, Germer S, Darnell R, Barzilai N, Freudenberg J, Atzmon G, Davies P. [P3-118]: INCREASED BURDEN OF RARE LOSS-OF-FUNCTION VARIANTS IN ALZHEIMER's DISEASE PATIENTS COMPARED TO CENTENARIANS Alzheimer's & Dementia. 13: P980-P980. DOI: 10.1016/J.Jalz.2017.06.1329 |
0.245 |
|
| 2009 |
Atzmon G, Barzilai N, Surks MI, Gabriely I. Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity. The Journal of Clinical Endocrinology and Metabolism. 94: 4768-75. PMID 19837933 DOI: 10.1210/Jc.2009-0808 |
0.245 |
|
| 2018 |
Hui KY, Fernandez-Hernandez H, Hu J, Schaffner A, Pankratz N, Hsu NY, Chuang LS, Carmi S, Villaverde N, Li X, Rivas M, Levine AP, Bao X, Labrias PR, Haritunians T, ... ... Barzilai N, et al. Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease. Science Translational Medicine. 10. PMID 29321258 DOI: 10.1126/Scitranslmed.Aai7795 |
0.244 |
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| 2011 |
Rajpathak SN, Liu Y, Ben-David O, Reddy S, Atzmon G, Crandall J, Barzilai N. Lifestyle factors of people with exceptional longevity. Journal of the American Geriatrics Society. 59: 1509-12. PMID 21812767 DOI: 10.1111/J.1532-5415.2011.03498.X |
0.242 |
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| 2012 |
Hall C, Derby C, Katz M, Sanders A, Barzilai N, Lipton R. P3-124: HDL cholesterol levels mediate association of CETP genotype with mortality Alzheimer's & Dementia. 8: P495-P495. DOI: 10.1016/J.Jalz.2012.05.1344 |
0.241 |
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| 2007 |
Barzilai N, Atzmon G, Derby CA, Bauman JM, Lipton RB. A genotype of exceptional longevity is associated with preservation of cognitive function. Neurology. 67: 2170-5. PMID 17190939 DOI: 10.1212/01.Wnl.0000249116.50854.65 |
0.238 |
|
| 2006 |
Terry DF, Wyszynski DF, Nolan VG, Atzmon G, Schoenhofen EA, Pennington JY, Andersen SL, Wilcox MA, Farrer LA, Barzilai N, Baldwin CT, Asea A. Serum heat shock protein 70 level as a biomarker of exceptional longevity. Mechanisms of Ageing and Development. 127: 862-8. PMID 17027907 DOI: 10.1016/J.Mad.2006.08.007 |
0.238 |
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| 2016 |
Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, ... ... Barzilai N, et al. A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF. Gastroenterology. PMID 27377463 DOI: 10.1053/J.Gastro.2016.06.045 |
0.237 |
|
| 2018 |
Lencz T, Yu J, Palmer C, Carmi S, Ben-Avraham D, Barzilai N, Bressman S, Darvasi A, Cho JH, Clark LN, Gümüş ZH, Joseph V, Klein R, Lipkin S, Offit K, et al. High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation. Human Genetics. PMID 29705978 DOI: 10.1007/S00439-018-1886-Z |
0.235 |
|
| 2014 |
Barzilai N, Atzmon G. Genes for Exceptional Longevity Annual Review of Gerontology and Geriatrics. 34: 171-188. DOI: 10.1891/0198-8794.34.171 |
0.235 |
|
| 2014 |
Carmi S, Hui KY, Kochav E, Liu X, Xue J, Grady F, Guha S, Upadhyay K, Ben-Avraham D, Mukherjee S, Bowen BM, Thomas T, Vijai J, Cruts M, Froyen G, ... ... Barzilai N, et al. Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins. Nature Communications. 5: 4835. PMID 25203624 DOI: 10.1038/Ncomms5835 |
0.235 |
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| 2003 |
Crandall J, Barzilai N. Treatment of diabetes mellitus in older people: oral therapy options. Journal of the American Geriatrics Society. 51: 272-4. PMID 12558728 DOI: 10.1046/J.1532-5415.2003.51070.X |
0.234 |
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| 2017 |
Knight CM, Gutierrez-Juarez R, Lam TKT, Arrieta-Cruz I, Huang L, Schwartz G, Barzilai N, Rossetti L. Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700. Diabetes. PMID 28982655 DOI: 10.2337/db17-er12C |
0.232 |
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| 2016 |
Cobb LJ, Lee C, Xiao J, Yen K, Wong RG, Nakamura HK, Mehta HH, Gao Q, Ashur C, Huffman DM, Wan J, Muzumdar R, Barzilai N, Cohen P. Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers. Aging. PMID 27070352 |
0.231 |
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| 2010 |
Schechter CB, Barzilai N, Crandall JP, Atzmon G. Cholesteryl ester transfer protein (CETP) genotype and reduced CETP levels associated with decreased prevalence of hypertension. Mayo Clinic Proceedings. 85: 522-6. PMID 20511482 DOI: 10.4065/Mcp.2009.0594 |
0.229 |
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| 2003 |
Butler RN, Austad SN, Barzilai N, Braun A, Helfand S, Larsen PL, McCormick AM, Perls TT, Shuldiner AR, Sprott RL, Warner HR. Longevity genes: from primitive organisms to humans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 58: 581-4. PMID 12865472 DOI: 10.1093/Gerona/58.7.B581 |
0.228 |
|
| 2018 |
Gurinovich A, Bae H, Andersen S, Puca A, Atzmon G, Barzilai N, Perls T, Sebastiani P. ETHNIC-SPECIFIC EFFECT OF APOE ALLELES ON EXTREME LONGEVITY Innovation in Aging. 2: 99-100. DOI: 10.1093/Geroni/Igy023.373 |
0.227 |
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| 2023 |
Milman S, Barzilai N. Discovering Biological Mechanisms of Exceptional Human Health Span and Life Span. Cold Spring Harbor Perspectives in Medicine. PMID 37137499 DOI: 10.1101/cshperspect.a041204 |
0.226 |
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| 2019 |
Karavani E, Zuk O, Zeevi D, Barzilai N, Stefanis NC, Hatzimanolis A, Smyrnis N, Avramopoulos D, Kruglyak L, Atzmon G, Lam M, Lencz T, Carmi S. Screening Human Embryos for Polygenic Traits Has Limited Utility. Cell. PMID 31761530 DOI: 10.1016/J.Cell.2019.10.033 |
0.226 |
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| 2013 |
Arjona Ferreira JC, Marre M, Barzilai N, Guo H, Golm GT, Sisk CM, Kaufman KD, Goldstein BJ. Efficacy and safety of sitagliptin versus glipizide in patients with type 2 diabetes and moderate-to-severe chronic renal insufficiency. Diabetes Care. 36: 1067-73. PMID 23248197 DOI: 10.2337/Dc12-1365 |
0.226 |
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| 2017 |
Ayers E, Shapiro M, Holtzer R, Barzilai N, Milman S, Verghese J. Symptoms of Apathy Independently Predict Incident Frailty and Disability in Community-Dwelling Older Adults. The Journal of Clinical Psychiatry. PMID 28406265 DOI: 10.4088/Jcp.15M10113 |
0.225 |
|
| 2008 |
Shlush LI, Atzmon G, Weisshof R, Behar D, Yudkovsky G, Barzilai N, Skorecki K. Ashkenazi Jewish centenarians do not demonstrate enrichment in mitochondrial haplogroup J. Plos One. 3: e3425. PMID 18923645 DOI: 10.1371/Journal.Pone.0003425 |
0.225 |
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| 2020 |
Sathyan S, Ayers E, Gao T, Weiss EF, Milman S, Verghese J, Barzilai N. Plasma proteomic profile of age, health span, and all-cause mortality in older adults. Aging Cell. e13250. PMID 33089916 DOI: 10.1111/acel.13250 |
0.224 |
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| 2019 |
Sathyan S, Ayers E, Gao T, Milman S, Barzilai N, Rockwood K, Verghese J. Frailty and Risk of Incident Motoric Cognitive Risk Syndrome. Journal of Alzheimer's Disease : Jad. PMID 31450502 DOI: 10.3233/Jad-190517 |
0.224 |
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| 2012 |
Lai JY, Atzmon G, Melamed ML, Hostetter TH, Crandall JP, Barzilai N, Bitzer M. Family history of exceptional longevity is associated with lower serum uric acid levels in Ashkenazi Jews. Journal of the American Geriatrics Society. 60: 745-50. PMID 22429185 DOI: 10.1111/J.1532-5415.2012.03902.X |
0.223 |
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| 2016 |
Kato K, Zweig R, Schechter CB, Barzilai N, Atzmon G. Positive attitude toward life, emotional expression, self-rated health, and depressive symptoms among centenarians and near-centenarians. Aging & Mental Health. 20: 930-9. PMID 26114814 DOI: 10.1080/13607863.2015.1056770 |
0.223 |
|
| 2012 |
Cai G, Atzmon G, Naj AC, Beecham GW, Barzilai N, Haines JL, Sano M, Pericak-Vance M, Buxbaum JD. Evidence against a role for rare ADAM10 mutations in sporadic Alzheimer disease. Neurobiology of Aging. 33: 416-417.e3. PMID 20381196 DOI: 10.1016/J.Neurobiolaging.2010.03.003 |
0.221 |
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| 2021 |
DeVito LM, Barzilai N, Cuervo AM, Niedernhofer LJ, Milman S, Levine M, Promislow D, Ferrucci L, Kuchel GA, Mannick J, Justice J, Gonzales MM, Kirkland JL, Cohen P, Campisi J. Extending human healthspan and longevity: a symposium report. Annals of the New York Academy of Sciences. PMID 34498278 DOI: 10.1111/nyas.14681 |
0.22 |
|
| 2006 |
Atzmon G, Muzumdar R, Budagov T, Barzilai N, Cohen P. OR05-1 THE GROWTH HORMONE RECEPTOR EXON-3 DELETION IS A MARKER FOR EXCEPTIONAL LONGEVITY Growth Hormone & Igf Research. 16: S9-S10. DOI: 10.1016/S1096-6374(07)70210-1 |
0.22 |
|
| 2010 |
Lipton RB, Hirsch J, Katz MJ, Wang C, Sanders AE, Verghese J, Barzilai N, Derby CA. Exceptional parental longevity associated with lower risk of Alzheimer's disease and memory decline. Journal of the American Geriatrics Society. 58: 1043-9. PMID 20487085 DOI: 10.1111/J.1532-5415.2010.02868.X |
0.216 |
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| 2021 |
Lin JR, Sin-Chan P, Napolioni V, Torres GG, Mitra J, Zhang Q, Jabalameli MR, Wang Z, Nguyen N, Gao T, Laudes M, Görg S, Franke A, Nebel A, Greicius MD, ... ... Barzilai N, et al. Rare genetic coding variants associated with human longevity and protection against age-related diseases. Nature Aging. 1: 783-794. PMID 37117627 DOI: 10.1038/s43587-021-00108-5 |
0.216 |
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| 2011 |
Perls T, Barzilai N. *100 Semi-supercentenarians and older as a proposed sample set for the Archon Genomics X PRIZE Validation Protocol* Nature Precedings. 6: 1-1. DOI: 10.1038/Npre.2011.5756.1 |
0.215 |
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| 2018 |
Justice JN, Ferrucci L, Newman AB, Aroda VR, Bahnson JL, Divers J, Espeland MA, Marcovina S, Pollak MN, Kritchevsky SB, Barzilai N, Kuchel GA. A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup. Geroscience. PMID 30151729 DOI: 10.1007/s11357-018-0042-y |
0.214 |
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| 2014 |
Heo H, Tozour J, Delahaye F, Zhao Y, Barzilai N, Einstein F. 810: Differentially methylated Regions as targets of adverse intrauterine environment American Journal of Obstetrics and Gynecology. 210: S394. DOI: 10.1016/J.Ajog.2013.10.843 |
0.212 |
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| 2010 |
Huffman DM, Barzilai N. Contribution of adipose tissue to health span and longevity. Interdisciplinary Topics in Gerontology. 37: 1-19. PMID 20703052 DOI: 10.1159/000319991 |
0.212 |
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| 2014 |
Milman S, Schulder-Katz M, Deluty J, Zimmerman ME, Crandall JP, Barzilai N, Melamed ML, Atzmon G. Individuals with exceptional longevity manifest a delayed association between vitamin D insufficiency and cognitive impairment. Journal of the American Geriatrics Society. 62: 153-8. PMID 24383816 DOI: 10.1111/Jgs.12601 |
0.211 |
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| 2014 |
Verghese J, Annweiler C, Ayers E, Barzilai N, Beauchet O, Bennett DA, Bridenbaugh SA, Buchman AS, Callisaya ML, Camicioli R, Capistrant B, Chatterji S, De Cock AM, Ferrucci L, Giladi N, et al. Motoric cognitive risk syndrome: multicountry prevalence and dementia risk. Neurology. 83: 718-26. PMID 25031288 DOI: 10.1212/Wnl.0000000000000717 |
0.211 |
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| 2024 |
Jabalameli MR, Lin JR, Zhang Q, Wang Z, Mitra J, Nguyen N, Gao T, Khusidman M, Sathyan S, Atzmon G, Milman S, Vijg J, Barzilai N, Zhang ZD. Polygenic prediction of human longevity on the supposition of pervasive pleiotropy. Scientific Reports. 14: 19981. PMID 39198552 DOI: 10.1038/s41598-024-69069-0 |
0.209 |
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| 2023 |
Jabalameli MR, Lin JR, Zhang Q, Wang Z, Mitra J, Nguyen N, Gao T, Khusidman M, Atzmon G, Milman S, Vijg J, Barzilai N, Zhang ZD. Polygenic prediction of human longevity on the supposition of pervasive pleiotropy. Medrxiv : the Preprint Server For Health Sciences. PMID 38168353 DOI: 10.1101/2023.12.10.23299795 |
0.209 |
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| 2014 |
Verghese J, Ayers E, Barzilai N, Bennett DA, Buchman AS, Holtzer R, Katz MJ, Lipton RB, Wang C. Motoric cognitive risk syndrome: Multicenter incidence study. Neurology. 83: 2278-84. PMID 25361778 DOI: 10.1212/Wnl.0000000000001084 |
0.207 |
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| 2015 |
Baskovich B, Hiraki S, Upadhyay K, Meyer P, Carmi S, Barzilai N, Darvasi A, Ozelius L, Peter I, Cho JH, Atzmon G, Clark L, Yu J, Lencz T, Pe'er I, et al. Expanded genetic screening panel for the Ashkenazi Jewish population. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 26334176 DOI: 10.1038/Gim.2015.123 |
0.207 |
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| 2017 |
Klein L, Gao T, Barzilai N, Milman S. Association between Sleep Patterns and Health in Families with Exceptional Longevity. Frontiers in Medicine. 4: 214. PMID 29276708 DOI: 10.3389/Fmed.2017.00214 |
0.207 |
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| 2020 |
Zhang ZD, Milman S, Lin JR, Wierbowski S, Yu H, Barzilai N, Gorbunova V, Ladiges WC, Niedernhofer LJ, Suh Y, Robbins PD, Vijg J. Genetics of extreme human longevity to guide drug discovery for healthy ageing. Nature Metabolism. PMID 32719537 DOI: 10.1038/s42255-020-0247-0 |
0.207 |
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| 2004 |
Barzilai N, Atzmon G, Schechter C, Lipton R, Shuldiner AR. Genetic Factors in Exceptional Longevity—Reply Jama. 291: 941-943. DOI: 10.1001/Jama.291.8.942 |
0.206 |
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| 2024 |
Aleksic S, Fleysher R, Weiss EF, Tal N, Darby T, Blumen HM, Vazquez J, Ye KQ, Gao T, Siegel SM, Barzilai N, Lipton ML, Milman S. Hypothalamic MRI-derived microstructure is associated with neurocognitive aging in humans. Neurobiology of Aging. 141: 102-112. PMID 38850591 DOI: 10.1016/j.neurobiolaging.2024.05.018 |
0.206 |
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| 2024 |
Ali A, Zhang Z, Gao T, Aleksic S, Gavathiotis E, Barzilai N, Milman S. Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity. Biorxiv : the Preprint Server For Biology. PMID 39416202 DOI: 10.1101/2024.10.11.617885 |
0.205 |
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| 2020 |
Yen K, Mehta HH, Kim SJ, Lue Y, Hoang J, Guerrero N, Port J, Bi Q, Navarrete G, Brandhorst S, Lewis KN, Wan J, Swerdloff R, Mattison JA, Buffenstein R, ... ... Barzilai N, et al. The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan. Aging. 12. PMID 32575074 DOI: 10.18632/aging.103534 |
0.205 |
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| 2016 |
Callisaya ML, Ayers E, Barzilai N, Ferrucci L, Guralnik JM, Lipton RB, Otahal P, Srikanth VK, Verghese J. Motoric Cognitive Risk Syndrome and Falls Risk: A Multi-Center Study. Journal of Alzheimer's Disease : Jad. PMID 27340851 DOI: 10.3233/Jad-160230 |
0.202 |
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| 2018 |
Justice JN, Niedernhofer L, Robbins PD, Aroda VR, Espeland MA, Kritchevsky SB, Kuchel GA, Barzilai N. Development of Clinical Trials to Extend Healthy Lifespan. Cardiovascular Endocrinology & Metabolism. 7: 80-83. PMID 30906924 DOI: 10.1097/XCE.0000000000000159 |
0.2 |
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| 2025 |
Ali A, Zhang ZD, Gao T, Aleksic S, Gavathiotis E, Barzilai N, Milman S. Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity. Scientific Reports. 15: 10199. PMID 40133344 DOI: 10.1038/s41598-025-94094-y |
0.2 |
|
| 2023 |
Oh HS, Rutledge J, Nachun D, Pálovics R, Abiose O, Moran-Losada P, Channappa D, Urey DY, Kim K, Sung YJ, Wang L, Timsina J, Western D, Liu M, Kohlfeld P, ... ... Barzilai N, et al. Organ aging signatures in the plasma proteome track health and disease. Nature. 624: 164-172. PMID 38057571 DOI: 10.1038/s41586-023-06802-1 |
0.199 |
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| 2000 |
Barzilai N. Body-mass index and mortality in a prospective cohort: Commentary Journal of the American Geriatrics Society. 48: 235-236. DOI: 10.1111/J.1532-5415.2000.Tb03925.X |
0.199 |
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| 2023 |
Saavedra D, Añé-Kourí AL, Barzilai N, Caruso C, Cho KH, Fontana L, Franceschi C, Frasca D, Ledón N, Niedernhofer LJ, Pereira K, Robbins PD, Silva A, Suarez GM, Berghe WV, et al. Aging and chronic inflammation: highlights from a multidisciplinary workshop. Immunity & Ageing : I & A. 20: 25. PMID 37291596 DOI: 10.1186/s12979-023-00352-w |
0.197 |
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| 2022 |
Couteur DGL, Barzilai N. New horizons in life extension, healthspan extension and exceptional longevity. Age and Ageing. 51. PMID 35932241 DOI: 10.1093/ageing/afac156 |
0.195 |
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| 2019 |
Lencz T, Karavani E, Lam M, Barzilai N, Stefanis N, Hatzimanolis A, Atzmon G, Carmi S. Sa51The Limits Of Polygenic Embryo Selection For Cognitive Ability European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.08.273 |
0.192 |
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| 2016 |
Perice L, Barzilai N, Verghese J, Weiss EF, Holtzer R, Cohen P, Milman S. Lower circulating insulin-like growth factor-I is associated with better cognition in females with exceptional longevity without compromise to muscle mass and function. Aging. PMID 27744417 DOI: 10.18632/aging.101063 |
0.189 |
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| 2020 |
Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, et al. ARDD 2020: from aging mechanisms to interventions. Aging. 12. PMID 33378272 DOI: 10.18632/aging.202454 |
0.186 |
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| 2020 |
Fulton-Howard B, Goate AM, Adelson RP, Koppel J, Gordon ML, Barzilai N, Atzmon G, Davies P, Freudenberg-Hua Y. Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers. Neurobiology of Aging. PMID 33164815 DOI: 10.1016/j.neurobiolaging.2020.09.014 |
0.185 |
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| 2025 |
Herzog C, Poganik JR, Barzilai N, Basisty N, Beerman I, Belsky DW, de Cabo R, Candia J, Faghri F, Horvath S, Maier AB, Perez V, Sen P, Moqri M, Gladyshev VN, et al. Biomarkers of Aging-NIA Joint Symposium 2024: New Insights Into Aging Biomarkers. Aging Cell. e70124. PMID 40525821 DOI: 10.1111/acel.70124 |
0.184 |
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| 2020 |
Dou Y, Darvas M, Sharma K, Mathieu J, Morton J, Tan H, Soto-Palma C, Angelini LA, McGowan SJ, Niedernhofer LJ, Suh Y, Robbins PD, Barzilai N, Ladiges WC. Development of an IGF1R longevity variant mouse line using CRISPR/Cas9 genome editing. Trends in Biomedical Research. 3. PMID 37113577 DOI: 10.15761/jtbr.1000121 |
0.183 |
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| 2021 |
Gurinovich A, Song Z, Zhang W, Federico A, Monti S, Andersen SL, Jennings LL, Glass DJ, Barzilai N, Millman S, Perls TT, Sebastiani P. Effect of longevity genetic variants on the molecular aging rate. Geroscience. PMID 33948810 DOI: 10.1007/s11357-021-00376-4 |
0.183 |
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| 2023 |
Forman DE, Kuchel GA, Newman JC, Kirkland JL, Volpi E, Taffet GE, Barzilai N, Pandey A, Kitzman DW, Libby P, Ferrucci L. Impact of Geroscience on Therapeutic Strategies for Older Adults With Cardiovascular Disease: JACC Scientific Statement. Journal of the American College of Cardiology. PMID 37389519 DOI: 10.1016/j.jacc.2023.05.038 |
0.183 |
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| 2023 |
Zhang X, Sanders JL, Boudreau RM, Arnold AM, Justice JN, Espeland MA, Kuchel GA, Barzilai N, Kuller LH, Lopez OL, Kritchevsky SB, Newman AB. Association of a blood-based aging biomarker index with death and chronic disease: Cardiovascular Health Study. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 37464278 DOI: 10.1093/gerona/glad172 |
0.181 |
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| 2024 |
Ying K, Castro JP, Shindyapina AV, Tyshkovskiy A, Moqri M, Goeminne LJE, Milman S, Zhang ZD, Barzilai N, Gladyshev VN. Depletion of loss-of-function germline mutations in centenarians reveals longevity genes. Nature Communications. 15: 9030. PMID 39424787 DOI: 10.1038/s41467-024-52967-2 |
0.179 |
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| 2023 |
Rolland Y, Sierra F, Ferrucci L, Barzilai N, De Cabo R, Mannick J, Oliva A, Evans W, Angioni D, De Souto Barreto P, Raffin J, Vellas B, Kirkland JL. Challenges in developing Geroscience trials. Nature Communications. 14: 5038. PMID 37598227 DOI: 10.1038/s41467-023-39786-7 |
0.178 |
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| 2021 |
Verghese J, Ayers E, Sathyan S, Lipton RB, Milman S, Barzilai N, Wang C. Trajectories of frailty in aging: Prospective cohort study. Plos One. 16: e0253976. PMID 34252094 DOI: 10.1371/journal.pone.0253976 |
0.178 |
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| 2022 |
Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, et al. Meeting Report: Aging Research and Drug Discovery. Aging. 14. PMID 35089871 DOI: 10.18632/aging.203859 |
0.178 |
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| 2024 |
Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, ... ... Barzilai N, et al. Validation of biomarkers of aging. Nature Medicine. 30: 360-372. PMID 38355974 DOI: 10.1038/s41591-023-02784-9 |
0.178 |
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| 2022 |
Gonzalez B, Tare A, Ryu S, Johnson SC, Atzmon G, Barzilai N, Kaeberlein M, Suh Y. High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity. Geroscience. PMID 35948858 DOI: 10.1007/s11357-022-00634-z |
0.177 |
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| 2021 |
Kim SS, Hudgins AD, Gonzalez B, Milman S, Barzilai N, Vijg J, Tu Z, Suh Y. A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations. Frontiers in Genetics. 12: 680560. PMID 34140970 DOI: 10.3389/fgene.2021.680560 |
0.177 |
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| 2023 |
Wang X, Jung HJ, Milholland B, Cui J, Tazearslan C, Atzmon G, Wang X, Yang J, Guo Q, Barzilai N, Robbins PD, Suh Y. The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity. Biorxiv : the Preprint Server For Biology. PMID 37292828 DOI: 10.1101/2023.05.19.541542 |
0.176 |
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| 2025 |
Bae H, Song Z, Ali A, Sasaki T, Tesi N, Lords H, Leshchyk A, Abe Y, Hirose N, Arai Y, Barzilai N, Weiss EF, Hulsman M, van der Lee S, van Schoor NM, et al. Increased Genetic Protection Against Alzheimer's Disease in Centenarians. Biorxiv : the Preprint Server For Biology. PMID 40501936 DOI: 10.1101/2025.06.02.657442 |
0.172 |
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| 2017 |
Barzilai N. TARGETING AGING WITH METFORMIN (TAME) Innovation in Aging. 1: 743-743. DOI: 10.1093/GERONI/IGX004.2682 |
0.171 |
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| 2024 |
Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, ... ... Barzilai N, et al. Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging. 16. PMID 39418098 DOI: 10.18632/aging.206135 |
0.171 |
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| 2007 |
Jerschow E, Anwar S, Barzilai N, Rosenstreich D. Macrophages Accumulation in Visceral and Subcutaneous Adipose Tissue Correlates with Age Journal of Allergy and Clinical Immunology. 119: S179. DOI: 10.1016/J.JACI.2006.12.066 |
0.17 |
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| 2024 |
Lin JR, Sin-Chan P, Napolioni V, Torres GG, Mitra J, Zhang Q, Jabalameli MR, Wang Z, Nguyen N, Gao T, Laudes M, Görg S, Franke A, Nebel A, Greicius MD, ... ... Barzilai N, et al. Author Correction: Rare genetic coding variants associated with human longevity and protection against age-related diseases. Nature Aging. PMID 39198704 DOI: 10.1038/s43587-024-00708-x |
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| 2025 |
Ferrucci L, Barzilai N, Belsky DW, Gladyshev VN. How to measure biological aging in humans. Nature Medicine. PMID 40011691 DOI: 10.1038/s41591-025-03550-9 |
0.168 |
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| 2019 |
Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, ... ... Barzilai N, et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. PMID 31118516 DOI: 10.1038/s41586-019-1231-2 |
0.165 |
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| 2012 |
Anisimov VN, Bartke A, Barzilai N, Batin MA, Blagosklonny MV, Brown-Borg H, Budovskaya Y, Campisi J, Friguet B, Fraifeld V, Franceschi C, Gems D, Gladyshev V, Gorbunova V, Gudkov AV, et al. The second international conference "genetics of aging and longevity". Aging. 4: 305-17. PMID 22661237 |
0.165 |
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| 2023 |
Moqri M, Herzog C, Poganik JR, Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, ... ... Barzilai N, et al. Biomarkers of aging for the identification and evaluation of longevity interventions. Cell. 186: 3758-3775. PMID 37657418 DOI: 10.1016/j.cell.2023.08.003 |
0.165 |
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| 2021 |
Cuervo AM, Huffman DM, Vijg J, Milman S, Singh R, Barzilai N. Einstein-Nathan Shock Center: translating the hallmarks of aging to extend human health span. Geroscience. PMID 34463901 DOI: 10.1007/s11357-021-00428-9 |
0.161 |
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| 2022 |
Aleksic S, Desai D, Ye K, Duran S, Gao T, Crandall J, Atzmon G, Barzilai N, Milman S. Integrity of hypothalamic-pituitary-testicular axis in exceptional longevity. Aging Cell. e13656. PMID 35770332 DOI: 10.1111/acel.13656 |
0.161 |
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| 2023 |
Zhu Y, Ryu S, Tare A, Barzilai N, Atzmon G, Suh Y. Targeted sequencing of the 9p21.3 region reveals association with reduced disease risks in Ashkenazi Jewish centenarians. Aging Cell. e13962. PMID 37605876 DOI: 10.1111/acel.13962 |
0.16 |
|
| 2022 |
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, ... ... Barzilai N, et al. A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A. The Embo Journal. e110393. PMID 36215696 DOI: 10.15252/embj.2021110393 |
0.16 |
|
| 2017 |
Gubbi S, Barzilai N, Crandall J, Verghese J, Milman S. The role of dietary patterns and exceptional parental longevity in healthy aging. Nutrition and Healthy Aging. 4: 247-254. PMID 29276794 DOI: 10.3233/NHA-170028 |
0.157 |
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| 2023 |
Milman S, Lerman B, Ayers E, Zhang Z, Sathyan S, Levine M, Ye K, Gao T, Higgins-Chen A, Barzilai N, Verghese J. Frailty Resilience Score: A Novel Measure of Frailty Resilience Associated with Protection from Frailty and Survival. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 37246648 DOI: 10.1093/gerona/glad138 |
0.156 |
|
| 2023 |
Sathyan S, Ayers E, Adhikari D, Gao T, Milman S, Barzilai N, Verghese J. Biological Age Acceleration and Motoric Cognitive Risk Syndrome. Annals of Neurology. PMID 36843279 DOI: 10.1002/ana.26624 |
0.154 |
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| 2021 |
Goodrich JK, Singer-Berk M, Son R, Sveden A, Wood J, England E, Cole JB, Weisburd B, Watts N, Caulkins L, Dornbos P, Koesterer R, Zappala Z, Zhang H, Maloney KA, ... ... Barzilai N, et al. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. Nature Communications. 12: 3505. PMID 34108472 DOI: 10.1038/s41467-021-23556-4 |
0.154 |
|
| 2021 |
Gurinovich A, Song Z, Zhang W, Federico A, Monti S, Andersen SL, Jennings LL, Glass DJ, Barzilai N, Millman S, Perls TT, Sebastiani P. Correction to: Effect of longevity genetic variants on the molecular aging rate. Geroscience. PMID 34143375 DOI: 10.1007/s11357-021-00400-7 |
0.153 |
|
| 2022 |
Sebastiani P, Song Z, Ellis D, Tian Q, Schwaiger-Haber M, Stancliffe E, Lustgarten MS, Funk CC, Baloni P, Yao CH, Joshi S, Marron MM, Gurinovich A, Li M, Leshchyk A, ... ... Barzilai N, et al. A metabolomic signature of the APOE2 allele. Geroscience. PMID 35997888 DOI: 10.1007/s11357-022-00646-9 |
0.153 |
|
| 2024 |
Herzog CMS, Goeminne LJE, Poganik JR, Barzilai N, Belsky DW, Betts-LaCroix J, Chen BH, Chen M, Cohen AA, Cummings SR, Fedichev PO, Ferrucci L, Fleming A, Fortney K, Furman D, et al. Challenges and recommendations for the translation of biomarkers of aging. Nature Aging. PMID 39285015 DOI: 10.1038/s43587-024-00683-3 |
0.149 |
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| 2025 |
Jacques E, Herzog C, Ying K, Tomusiak A, Kasamoto J, Sehgal R, Paulson S, Reinhard J, Träuble J, Hastings WJ, Tyshkovskiy A, Hägg S, Earls JC, Behrens CE, Lasky-Su J, ... ... Barzilai N, et al. Invigorating discovery and clinical translation of aging biomarkers. Nature Aging. PMID 40164770 DOI: 10.1038/s43587-025-00838-w |
0.148 |
|
| 2021 |
Ryu S, Han J, Norden-Krichmar TM, Zhang Q, Lee S, Zhang Z, Atzmon G, Niedernhofer LJ, Robbins PD, Barzilai N, Schork NJ, Suh Y. Genetic signature of human longevity in PKC and NF-κB signaling. Aging Cell. e13362. PMID 34197020 DOI: 10.1111/acel.13362 |
0.147 |
|
| 2024 |
Andrawus M, David GB, Terziyska I, Sharvit L, Bergman A, Barzilai N, Raj SM, Govindaraju DR, Atzmon G. Genome integrity as a potential index of longevity in Ashkenazi Centenarian's families. Geroscience. PMID 38724875 DOI: 10.1007/s11357-024-01178-0 |
0.147 |
|
| 2025 |
Milman S, Montgomery A, Barzilai N, Gao T, Wilson KA, Perls T, Leahy AMG, Burgis E, Ruxton M, Jain P, Shuldiner AR. Tailored Approach to Designing a Digital Research Platform for Adults Aged 95 and older: SuperAgers Family Study. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 39905661 DOI: 10.1093/gerona/glaf016 |
0.144 |
|
| 2011 |
Tabatabaie V, Atzmon G, Rajpathak SN, Freeman R, Barzilai N, Crandall J. Exceptional longevity is associated with decreased reproduction. Aging. 3: 1202-5. PMID 22199025 |
0.144 |
|
| 2024 |
Miller B, Kim SJ, Cao K, Mehta HH, Thumaty N, Kumagai H, Iida T, McGill C, Pike CJ, Nurmakova K, Levine ZA, Sullivan PM, Yen K, Ertekin-Taner N, Atzmon G, ... Barzilai N, et al. Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology. Aging Cell. e14153. PMID 38520065 DOI: 10.1111/acel.14153 |
0.143 |
|
| 2024 |
Vazquez JP, Verghese J, Barzilai N, Milman S, Blumen HM. White Matter Hyperintensities Are Associated with Slower Gait Speed in Older Adults without Dementia. Neuro-Degenerative Diseases. 1-9. PMID 39025052 DOI: 10.1159/000538944 |
0.139 |
|
| 2021 |
Hindy G, Dornbos P, Chaffin MD, Liu DJ, Wang M, Selvaraj MS, Zhang D, Park J, Aguilar-Salinas CA, Antonacci-Fulton L, Ardissino D, Arnett DK, Aslibekyan S, Atzmon G, Ballantyne CM, ... ... Barzilai N, et al. Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. American Journal of Human Genetics. PMID 34932938 DOI: 10.1016/j.ajhg.2021.11.021 |
0.134 |
|
| 2024 |
Blumen HM, Jayakody O, Ayers E, Barzilai N, Habeck C, Milman S, Stern Y, Weiss EF, Verghese J. Cognitive reserve proxies are associated with age-related cognitive decline - Not age-related gait speed decline. Neurobiology of Aging. 141: 46-54. PMID 38820770 DOI: 10.1016/j.neurobiolaging.2024.05.012 |
0.13 |
|
| 2022 |
Bae H, Gurinovich A, Karagiannis TT, Song Z, Leshchyk A, Li M, Andersen SL, Arbeev K, Yashin A, Zmuda J, An P, Feitosa M, Giuliani C, Franceschi C, Garagnani P, ... ... Barzilai N, et al. A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants. International Journal of Molecular Sciences. 24. PMID 36613555 DOI: 10.3390/ijms24010116 |
0.13 |
|
| 2021 |
Jayakody O, Breslin M, Ayers E, Verghese J, Barzilai N, Milman S, Weiss E, Blumen HM. Relative Trajectories of Gait and Cognitive Decline in Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 34791239 DOI: 10.1093/gerona/glab346 |
0.129 |
|
| 2025 |
Woods T, Palmarini N, Corner L, Barzilai N, Maier AB, Sagner M, Bensz J, Strygin A, Yadala N, Kern C, Ward P, Ferrucci L, Bischof EY, Barker R, Shiels PG, et al. Cities, communities and clinics can be testbeds for human exposome and aging research. Nature Medicine. PMID 40075229 DOI: 10.1038/s41591-025-03519-8 |
0.122 |
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| 2025 |
Delpratt N, Barzilai N, Milman S, Aleksic S, Weiss E, Verghese J, Blumen HM. Gray Matter Covariance Networks Associated with Parental Longevity - Results from the LonGenity Study. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 40292561 DOI: 10.1093/gerona/glaf066 |
0.116 |
|
| 2022 |
Sazonovs A, Stevens CR, Venkataraman GR, Yuan K, Avila B, Abreu MT, Ahmad T, Allez M, Ananthakrishnan AN, Atzmon G, Baras A, Barrett JC, Barzilai N, Beaugerie L, Beecham A, et al. Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility. Nature Genetics. PMID 36038634 DOI: 10.1038/s41588-022-01156-2 |
0.113 |
|
| 2022 |
Jayakody O, Breslin M, Ayers E, Verghese J, Barzilai N, Weiss E, Milman S, Blumen HM. Age-related changes in gait domains: Results from the LonGenity study. Gait & Posture. 100: 8-13. PMID 36463714 DOI: 10.1016/j.gaitpost.2022.11.009 |
0.111 |
|
| 2011 |
Barzilai N, Guo H, Mahoney EM, Caporossi S, Golm GT, Langdon RB, Williams-Herman D, Kaufman KD, Amatruda JM, Goldstein BJ, Steinberg H. Efficacy and tolerability of sitagliptin monotherapy in elderly patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Current Medical Research and Opinion. 27: 1049-58. PMID 21428727 DOI: 10.1185/03007995.2011.568059 |
0.109 |
|
| 2015 |
Deluty JA, Atzmon G, Crandall J, Barzilai N, Milman S. The influence of gender on inheritance of exceptional longevity. Aging. 7: 412-8. PMID 26142631 DOI: 10.18632/aging.100763 |
0.104 |
|
| 2024 |
Ali A, Milman S, Weiss EF, Gao T, Napolioni V, Barzilai N, Zhang ZD, Lin JR. Rare genetic coding variants associated with age-related episodic memory decline implicate distinct memory pathologies in the hippocampus. Medrxiv : the Preprint Server For Health Sciences. PMID 38826255 DOI: 10.1101/2024.05.21.24307692 |
0.103 |
|
| 2021 |
Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, ... ... Barzilai N, et al. Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature Communications. 12: 2463. PMID 33893282 DOI: 10.1038/s41467-021-22613-2 |
0.1 |
|
| 1992 |
Schadlow VC, Barzilai N, Deutsch PJ. Regulation of gene expression in PC12 cells via an activator of dual second messengers: pituitary adenylate cyclase activating polypeptide. Molecular Biology of the Cell. 3: 941-51. PMID 1392081 DOI: 10.1091/mbc.3.8.941 |
0.099 |
|
| 2024 |
Ali A, Milman S, Weiss EF, Gao T, Napolioni V, Barzilai N, Zhang ZD, Lin JR. Genetic variants associated with age-related episodic memory decline implicate distinct memory pathologies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39559945 DOI: 10.1002/alz.14379 |
0.098 |
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| 2022 |
Waldman S, Backenroth D, Harney É, Flohr S, Neff NC, Buckley GM, Fridman H, Akbari A, Rohland N, Mallick S, Olalde I, Cooper L, Lomes A, Lipson J, Cano Nistal J, ... ... Barzilai N, et al. Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14 century. Cell. 185: 4703-4716.e16. PMID 36455558 DOI: 10.1016/j.cell.2022.11.002 |
0.095 |
|
| 2024 |
Sathyan S, Milman S, Ayers E, Gao T, Verghese J, Barzilai N. Plasma proteomic profile of abdominal obesity in older adults. Obesity (Silver Spring, Md.). PMID 38439214 DOI: 10.1002/oby.24000 |
0.095 |
|
| 2015 |
Han J, Atzmon G, Barzilai N, Suh Y. Genetic variation in Sirtuin 1 (SIRT1) is associated with lipid profiles but not with longevity in Ashkenazi Jews Translational Research. 165: 480-481. DOI: 10.1016/j.trsl.2014.09.008 |
0.093 |
|
| 2013 |
Kato K, Zweig R, Schechter CB, Verghese J, Barzilai N, Atzmon G. Personality, self-rated health, and cognition in centenarians: do personality and self-rated health relate to cognitive function in advanced age? Aging. 5: 183-91. PMID 23524310 DOI: 10.18632/aging.100545 |
0.089 |
|
| 2019 |
Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, ... ... Barzilai N, et al. Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. The American Journal of Psychiatry. 176: 217-227. PMID 30818990 DOI: 10.1176/Appi.Ajp.2018.18070857 |
0.086 |
|
| 2012 |
Kato K, Zweig R, Barzilai N, Atzmon G. Positive attitude towards life and emotional expression as personality phenotypes for centenarians. Aging. 4: 359-67. PMID 22626632 DOI: 10.18632/aging.100456 |
0.084 |
|
| 1993 |
Deutsch PJ, Schadlow VC, Barzilai N. 38-Amino acid form of pituitary adenylate cyclase activating peptide induces process outgrowth in human neuroblastoma cells. Journal of Neuroscience Research. 35: 312-20. PMID 8102409 DOI: 10.1002/jnr.490350311 |
0.082 |
|
| 2021 |
Lencz T, Yu J, Khan RR, Flaherty E, Carmi S, Lam M, Ben-Avraham D, Barzilai N, Bressman S, Darvasi A, Cho JH, Clark LN, Gümüş ZH, Vijai J, Klein RJ, et al. Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia. Neuron. PMID 33756103 DOI: 10.1016/j.neuron.2021.03.004 |
0.082 |
|
| 1985 |
Handzel ZT, Galili-Weisstub E, Burstein R, Berner Y, Pecht M, Netzer L, Trainin N, Barzilai N, Levin S, Bentwich Z. Immune derangements in asymptomatic male homosexuals in Israel: a pre-AIDS condition? Annals of the New York Academy of Sciences. 437: 549-53. PMID 6242007 DOI: 10.1111/J.1749-6632.1984.Tb37183.X |
0.081 |
|
| 2023 |
Erickson SM, Fenno SL, Barzilai N, Kuchel G, Bartley JM, Justice JN, Buse JB, Bramante CT. Metformin for Treatment of Acute COVID-19: Systematic Review of Clinical Trial Data Against SARS-CoV-2. Diabetes Care. 46: 1432-1442. PMID 37339345 DOI: 10.2337/dc22-2539 |
0.079 |
|
| 2019 |
Adelson RP, Renton AE, Li W, Barzilai N, Atzmon G, Goate AM, Davies P, Freudenberg-Hua Y. Empirical design of a variant quality control pipeline for whole genome sequencing data using replicate discordance. Scientific Reports. 9: 16156. PMID 31695094 DOI: 10.1038/S41598-019-52614-7 |
0.078 |
|
| 1982 |
Ashkenazi A, Levin S, Idar D, Handzel ZT, Altman Y, Or A, Barzilai N. Cellular immunity in children with coeliac disease. European Journal of Pediatrics. 138: 250-3. PMID 6749506 DOI: 10.1007/BF00441211 |
0.07 |
|
| 2023 |
Milman S, Barzilai N, Wilson KA, Van der Willik O, Lederman S, Perls T, Gao T, Leahy AM, Jain P, Montgomery A, Shuldiner AR. SuperAger Initiative: unlocking the genetic potential of exceptional longevity. Nature Aging. PMID 37202472 DOI: 10.1038/s43587-023-00429-7 |
0.067 |
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| 2018 |
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Barzilai N, et al. Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 5: 180002. PMID 29360107 DOI: 10.1038/sdata.2018.2 |
0.067 |
|
| 2023 |
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, ... ... Barzilai N, et al. A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A. The Embo Journal. 42: e113326. PMID 36722290 DOI: 10.15252/embj.2022113326 |
0.065 |
|
| 2019 |
Rivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, et al. Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population. Plos Genetics. 15: e1008190. PMID 31145742 DOI: 10.1371/journal.pgen.1008190 |
0.06 |
|
| 2022 |
Groeger JL, Ayers E, Barzilai N, Beauchet O, Callisaya M, Torossian MR, Derby C, Doi T, Lipton RB, Milman S, Nakakubo S, Shimada H, Srikanth V, Wang C, Verghese J. Inflammatory biomarkers and motoric cognitive risk syndrome: Multicohort survey. Cerebral Circulation - Cognition and Behavior. 3: 100151. PMID 36324399 DOI: 10.1016/j.cccb.2022.100151 |
0.06 |
|
| 2024 |
Nagamalla V, Verghese J, Ayers E, Barzilai N, Beauchet O, Lipton RB, Shimada H, Srikanth VK, Blumen HM. Distinct Patterns of Brain Atrophy in amnestic Mild Cognitive Impairment and Motoric Cognitive Risk Syndromes. Neuro-Degenerative Diseases. PMID 39102797 DOI: 10.1159/000540512 |
0.057 |
|
| 2022 |
Leung Y, Barzilai N, Batko-Szwaczka A, Beker N, Boerner K, Brayne C, Brodaty H, Cheung KS, Corrada MM, Crawford JD, Galbussera AA, Gondo Y, Holstege H, Hulsman M, Ishioka YL, et al. Cognition, function, and prevalent dementia in centenarians and near-centenarians: An individual participant data (IPD) meta-analysis of 18 studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36453627 DOI: 10.1002/alz.12828 |
0.056 |
|
| 2025 |
Gomez GT, Sathyan S, Chen J, Fornage M, Schlosser P, Peng Z, Cordon J, Palta P, Sullivan KJ, Tin A, Windham BG, Gottesman RF, Barzilai N, Milman S, Verghese J, et al. Plasma proteomic characterization of motoric cognitive risk and mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. e14429. PMID 39887533 DOI: 10.1002/alz.14429 |
0.053 |
|
| 2024 |
Andrawus M, David GB, Terziyska I, Sharvit L, Bergman A, Barzilai N, Raj SM, Govindaraju DR, Atzmon G. Correction to: Genome integrity as a potential index of longevity in Ashkenazi Centenarian's families. Geroscience. PMID 38888877 DOI: 10.1007/s11357-024-01253-6 |
0.047 |
|
| 1992 |
Deutsch P, Sun Y, Schadlow V, Johnson C, Espinoza K, Barzilai N. PACAP38, more potently than PACAP 27, stimulates dual signaling cascades and neurite outgrowth in PC12 cells Regulatory Peptides. 37: 318. DOI: 10.1016/0167-0115(92)90633-6 |
0.046 |
|
| 2025 |
Barzilai N, Starr R, Verdin E, Niedernhofer LJ, Bertram A, Lithgow GJ, Maier AB. Accelerating the promise of geroscience through The Academy of Health & Lifespan Research. Nature Aging. PMID 40055476 DOI: 10.1038/s43587-025-00832-2 |
0.042 |
|
| 2022 |
Woods T, Palmarini N, Corner L, Barzilai N, Bethell LJ, Cox LS, Eyre H, Ferrucci L, Fried L, Furman D, Kennedy B, Roddam A, Scott A, Siow RC. Quantum Healthy Longevity for healthy people, planet, and growth. The Lancet. Healthy Longevity. PMID 36384162 DOI: 10.1016/S2666-7568(22)00267-7 |
0.04 |
|
| 2018 |
Serrano M, Barzilai N. Targeting senescence. Nature Medicine. PMID 30082861 DOI: 10.1038/s41591-018-0141-4 |
0.039 |
|
| 2023 |
Boekstein N, Barzilai N, Bertram A, Betts-LaCroix J, Fortney K, Helliwell SB, Hufford M, Mannick J, McLaughlin J, Mellon J, Morgen E, Regge N, Robinton DA, Sinclair DA, Young S, et al. Defining a longevity biotechnology company. Nature Biotechnology. PMID 37365260 DOI: 10.1038/s41587-023-01854-0 |
0.03 |
|
| 1994 |
Kagan A, Sinay-Trieman L, Czernobilsky B, Barzilai N, Bar-Khayim Y. Is the association between crescentic glomerulonephritis and renal cell carcinoma coincidental? Nephron. 65: 642-3. PMID 8302427 DOI: 10.1159/000187581 |
0.026 |
|
| 1995 |
Guy M, Singer D, Barzilai N, Eisenkraft S. Primary classic Kaposi's sarcoma of glans penis--appearance on magnetic resonance imaging. British Journal of Urology. 74: 521-2. PMID 7820438 DOI: 10.1111/j.1464-410X.1994.tb00439.x |
0.012 |
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