| Year |
Citation |
Score |
| 2023 |
Puchner KP, Bottazzi ME, Periago V, Grobusch M, Maizels R, McCarthy J, Lee B, Gaspari E, Diemert D, Hotez P. Vaccine value profile for Hookworm. Vaccine. PMID 37863671 DOI: 10.1016/j.vaccine.2023.05.013 |
0.387 |
|
| 2023 |
Diemert DJ, Correa-Oliveira R, Fraga CG, Talles F, Silva MR, Patel SM, Galbiati S, Kennedy JK, Lundeen JS, Gazzinelli MF, Li G, Hoeweler L, Deye GA, Bottazzi ME, Hotez PJ, et al. A randomized, controlled Phase 1b trial of the Sm-TSP-2 Vaccine for intestinal schistosomiasis in healthy Brazilian adults living in an endemic area. Plos Neglected Tropical Diseases. 17: e0011236. PMID 36996185 DOI: 10.1371/journal.pntd.0011236 |
0.312 |
|
| 2022 |
Betouke Ongwe ME, Mouwenda YD, Stam KA, Kremsner PG, Lell B, Diemert D, Bethony J, Bottazzi ME, Hotez PJ, Leeuwen RV, Grobusch MP, Adegnika AA, Mayboroda OA, Yazdanbakhsh M. Investigation of urinary metabolomics in a phase I hookworm vaccine trial in Gabon. Plos One. 17: e0275013. PMID 36155987 DOI: 10.1371/journal.pone.0275013 |
0.35 |
|
| 2022 |
Diemert DJ, Zumer M, Campbell D, Grahek S, Li G, Peng J, Elena Bottazzi M, Hotez P, Bethony J. Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-naïve adults. Vaccine. 40: 6084-6092. PMID 36114129 DOI: 10.1016/j.vaccine.2022.09.017 |
0.34 |
|
| 2022 |
Zhan B, Bottazzi ME, Hotez PJ, Lustigman S. Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With . Frontiers in Cellular and Infection Microbiology. 12: 869039. PMID 35444961 DOI: 10.3389/fcimb.2022.869039 |
0.376 |
|
| 2021 |
Gazzinelli-Guimarães AC, Nogueira DS, Amorim CCO, Oliveira FMS, Coqueiro-Dos-Santos A, Carvalho SAP, Kraemer L, Barbosa FS, Fraga VG, Santos FV, de Castro JC, Russo RC, Akamatsu MA, Ho PL, Bottazzi ME, ... Hotez PJ, et al. ASCVac-1, a Multi-Peptide Chimeric Vaccine, Protects Mice Against Infection. Frontiers in Immunology. 12: 788185. PMID 34992603 DOI: 10.3389/fimmu.2021.788185 |
0.332 |
|
| 2021 |
Loukas A, Maizels RM, Hotez PJ. The yin and yang of human soil-transmitted helminth infections. International Journal For Parasitology. 51: 1243-1253. PMID 34774540 DOI: 10.1016/j.ijpara.2021.11.001 |
0.342 |
|
| 2021 |
Mouwenda YD, Betouke Ongwe ME, Sonnet F, Stam KA, Labuda LA, De Vries S, Grobusch MP, Zinsou FJ, Honkpehedji YJ, Dejon Agobe JC, Diemert DJ, van Leeuwen R, Bottazzi ME, Hotez PJ, Kremsner PG, et al. Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon. Plos Neglected Tropical Diseases. 15: e0009732. PMID 34597297 DOI: 10.1371/journal.pntd.0009732 |
0.33 |
|
| 2020 |
de Castro JC, de Almeida LV, Cardoso MS, Oliveira FMS, Nogueira DS, Reis-Cunha JL, Magalhaes LMD, Zhan B, Bottazzi ME, Hotez PJ, Bueno LL, Bartholomeu DC, Fujiwara RT. Vaccination with chimeric protein induces protection in murine model against ascariasis. Vaccine. PMID 33248854 DOI: 10.1016/j.vaccine.2020.11.046 |
0.345 |
|
| 2020 |
Adegnika AA, de Vries SG, Zinsou FJ, Honkepehedji YJ, Dejon Agobé JC, Vodonou KG, Bikangui R, Bouyoukou Hounkpatin A, Bache EB, Massinga Loembe M, van Leeuwen R, Molemans M, Kremsner PG, Yazdanbakhsh M, Hotez PJ, et al. Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial. The Lancet. Infectious Diseases. PMID 32926834 DOI: 10.1016/S1473-3099(20)30288-7 |
0.393 |
|
| 2020 |
Mejia R, Hotez P, Bottazzi ME. Global COVID-19 Efforts as the Platform to Achieving the Sustainable Development Goals. Current Tropical Medicine Reports. 1-5. PMID 32844081 DOI: 10.1007/S40475-020-00209-Y |
0.316 |
|
| 2020 |
Ness TE, Agrawal V, Bedard K, Ouellette L, Erickson TA, Hotez P, Weatherhead JE. Maternal Hookworm Infection and Its Effects on Maternal Health: A Systematic Review and Meta-Analysis. The American Journal of Tropical Medicine and Hygiene. PMID 32840198 DOI: 10.4269/Ajtmh.20-0503 |
0.305 |
|
| 2020 |
Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, ... ... Hotez P, et al. Correction: Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults. Plos Neglected Tropical Diseases. 14: e0008670. PMID 32804987 DOI: 10.1371/Journal.Pntd.0008670 |
0.314 |
|
| 2020 |
Franco-Paredes C, Jankousky K, Schultz J, Bernfeld J, Cullen K, Quan NG, Kon S, Hotez P, Henao-Martínez AF, Krsak M. COVID-19 in jails and prisons: A neglected infection in a marginalized population. Plos Neglected Tropical Diseases. 14: e0008409. PMID 32569274 DOI: 10.1371/Journal.Pntd.0008409 |
0.348 |
|
| 2020 |
Versteeg L, Wei J, Liu Z, Keegan B, Fujiwara RT, Jones KM, Asojo O, Strych U, Bottazzi ME, Hotez PJ, Zhan B. Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection. Plos Neglected Tropical Diseases. 14: e0008057. PMID 32053593 DOI: 10.1371/Journal.Pntd.0008057 |
0.387 |
|
| 2019 |
Gostin LO, Hodge JG, Bloom BR, El-Mohandes A, Fielding J, Hotez P, Kurth A, Larson HJ, Orenstein WA, Rabin K, Ratzan SC, Salmon D. The public health crisis of underimmunisation: a global plan of action. The Lancet. Infectious Diseases. PMID 31706795 DOI: 10.1016/S1473-3099(19)30558-4 |
0.352 |
|
| 2019 |
Versteeg L, Almutairi MM, Hotez PJ, Pollet J. Enlisting the mRNA Vaccine Platform to Combat Parasitic Infections. Vaccines. 7. PMID 31547081 DOI: 10.3390/vaccines7040122 |
0.339 |
|
| 2019 |
P JG, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans. Plos Neglected Tropical Diseases. 13: e0007730. PMID 31525197 DOI: 10.1371/Journal.Pntd.0007730 |
0.32 |
|
| 2019 |
Ratzan SC, Bloom BR, El-Mohandes A, Fielding J, Gostin LO, Hodge JG, Hotez P, Kurth A, Larson HJ, Nurse J, Omer SB, Orenstein WA, Salmon D, Rabin K. The Salzburg Statement on Vaccination Acceptance. Journal of Health Communication. 1-3. PMID 31262227 DOI: 10.1080/10810730.2019.1622611 |
0.33 |
|
| 2019 |
Barry MA, Versteeg L, Wang Q, Pollet J, Zhan B, Gusovsky F, Bottazzi ME, Hotez PJ, Jones KM. A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection. Plos Neglected Tropical Diseases. 13: e0007413. PMID 31145733 DOI: 10.1371/journal.pntd.0007413 |
0.305 |
|
| 2019 |
Hotez P. The physician-scientist: defending vaccines and combating antiscience. The Journal of Clinical Investigation. 130. PMID 31033486 DOI: 10.1172/Jci129121 |
0.33 |
|
| 2019 |
Hotez P. America and Europe's new normal: the return of vaccine-preventable diseases. Pediatric Research. PMID 30812027 DOI: 10.1038/S41390-019-0354-3 |
0.336 |
|
| 2019 |
Zinsou JF, Honpkehedji J, Agobe Jean Claude D, Adegbite BR, Ronald Edoa J, Van Leeuwen R, Diemert D, Elena Botazzi M, Kremsner PG, Yazdanbakhsh M, Hotez P, P Grobusch M, Akim Adegnika A, De Vries S. OC 8521 PRELIMINARY REPORT ON SAFETY OF CO-ADMINISTERED HUMAN HOOKWORM VACCINE CANDIDATES NA-APR-1 (M74)/ALHYDROGEL® AND NA-GST-1/ALHYDROGEL® IN GABONESE CHILDREN Bmj Global Health. 4: A12.1-A12. DOI: 10.1136/Bmjgh-2019-Edc.28 |
0.343 |
|
| 2018 |
Zhan B, Arumugam S, Kennedy MW, Tricoche N, Lian LY, Asojo OA, Bennuru S, Bottazzi ME, Hotez PJ, Lustigman S, Klei TR. Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils. Plos Neglected Tropical Diseases. 12: e0006772. PMID 30296268 DOI: 10.1371/Journal.Pntd.0006772 |
0.32 |
|
| 2018 |
Briggs N, Wei J, Versteeg L, Zhan B, Keegan B, Damania A, Pollet J, Hayes KS, Beaumier C, Seid CA, Leong J, Grencis RK, Bottazzi ME, Sastry KJ, Hotez PJ. Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm. Plos Pathogens. 14: e1007273. PMID 30153307 DOI: 10.1371/journal.ppat.1007273 |
0.323 |
|
| 2018 |
Bouchery T, Filbey K, Shepherd A, Chandler J, Patel D, Schmidt A, Camberis M, Peignier A, Smith AAT, Johnston K, Painter G, Pearson M, Giacomin P, Loukas A, Bottazzi ME, ... Hotez P, et al. A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. Plos Pathogens. 14: e1006931. PMID 29566094 DOI: 10.1371/Journal.Ppat.1006931 |
0.391 |
|
| 2018 |
Villanueva-Lizama LE, Cruz-Chan JV, Aguilar-Cetina ADC, Herrera-Sanchez LF, Rodriguez-Perez JM, Rosado-Vallado ME, Ramirez-Sierra MJ, Ortega-Lopez J, Jones K, Hotez P, Bottazzi ME, Dumonteil E. Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico. Plos Neglected Tropical Diseases. 12: e0006240. PMID 29377898 DOI: 10.1371/Journal.Pntd.0006240 |
0.335 |
|
| 2017 |
Lustigman S, Makepeace BL, Klei TR, Babayan SA, Hotez P, Abraham D, Bottazzi ME. Onchocerca volvulus: The Road from Basic Biology to a Vaccine. Trends in Parasitology. PMID 28958602 DOI: 10.1016/J.Pt.2017.08.011 |
0.352 |
|
| 2017 |
Wei J, Versteeg L, Liu Z, Keegan B, Gazzinelli-Guimarães AC, Fujiwara RT, Briggs N, Jones KM, Strych U, Beaumier CM, Bottazzi ME, Hotez PJ, Zhan B. Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response. Plos Neglected Tropical Diseases. 11: e0005769. PMID 28708895 DOI: 10.1371/journal.pntd.0005769 |
0.33 |
|
| 2017 |
Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, ... ... Hotez P, et al. Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults. Plos Neglected Tropical Diseases. 11: e0005574. PMID 28464026 DOI: 10.1371/Journal.Pntd.0005574 |
0.313 |
|
| 2017 |
Asojo OA, Kelleher A, Liu Z, Pollet J, Hudspeth EM, Rezende WC, Groen MJ, Seid CA, Abdeladhim M, Townsend S, de Castro W, Mendes-Sousa A, Bartholomeu DC, Fujiwara RT, Bottazzi ME, ... Hotez PJ, et al. Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis. Plos Neglected Tropical Diseases. 11: e0005374. PMID 28278244 DOI: 10.1371/Journal.Pntd.0005374 |
0.318 |
|
| 2017 |
Brelsford JB, Plieskatt JL, Yakovleva A, Jariwala A, Keegan BP, Peng J, Xia P, Li G, Campbell D, Periago MV, Correa-Oliveira R, Bottazzi ME, Hotez PJ, Diemert D, Bethony JM. Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine. Plos Neglected Tropical Diseases. 11: e0005385. PMID 28192438 DOI: 10.1371/Journal.Pntd.0005385 |
0.383 |
|
| 2017 |
Eppes C, Rac M, Dunn J, Versalovic J, Murray KO, Suter MA, Sanz Cortes M, Espinoza J, Seferovic MD, Lee W, Hotez P, Mastrobattista J, Clark SL, Belfort MA, Aagaard KM. Testing for Zika Virus (ZIKV) Infection in Pregnancy: Key Concepts to Deal with an Emerging Epidemic. American Journal of Obstetrics and Gynecology. PMID 28126366 DOI: 10.1016/J.Ajog.2017.01.020 |
0.356 |
|
| 2017 |
Adegnika A, Vries SD, Zinsou FJ, Honkpehedji J, Dejon JC, Loembe MM, Bache B, Pakker N, Leeuwen RV, Hounkpatin AB, Kremsner P, Yazdanbakhsh M, Lell B, Bethony J, Hotez P, et al. SAFETY AND IMMUNOGENICITY OF CO-ADMINISTERED HOOKWORM VACCINE CANDIDATES NA-GST-1 AND NA-APR-1 WITH ALHYDROGEL® AND GLUCOPYRANOSYL-LIPID A IN GABONESE ADULTS: INTERIM RESULTS Bmj Global Health. 2: A12.3-A13. DOI: 10.1136/Bmjgh-2016-000260.29 |
0.359 |
|
| 2016 |
Loukas A, Hotez PJ, Diemert D, Yazdanbakhsh M, McCarthy JS, Correa-Oliveira R, Croese J, Bethony JM. Hookworm infection. Nature Reviews. Disease Primers. 2: 16088. PMID 27929101 DOI: 10.1038/nrdp.2016.88 |
0.322 |
|
| 2016 |
Navarro S, Pickering DA, Ferreira IB, Jones L, Ryan S, Troy S, Leech A, Hotez PJ, Zhan B, Laha T, Prentice R, Sparwasser T, Croese J, Engwerda CR, Upham JW, et al. Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine. 8: 362ra143. PMID 27797959 DOI: 10.1126/Scitranslmed.Aaf8807 |
0.331 |
|
| 2016 |
Wei J, Damania A, Gao X, Liu Z, Mejia R, Mitreva M, Strych U, Bottazzi ME, Hotez PJ, Zhan B. The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates. Parasites & Vectors. 9: 518. PMID 27677574 DOI: 10.1186/s13071-016-1795-8 |
0.394 |
|
| 2016 |
Bartsch SM, Hotez PJ, Asti L, Zapf KM, Bottazzi ME, Diemert DJ, Lee BY. The Global Economic and Health Burden of Human Hookworm Infection. Plos Neglected Tropical Diseases. 10: e0004922. PMID 27607360 DOI: 10.1371/journal.pntd.0004922 |
0.322 |
|
| 2016 |
Hotez PJ, Strych U, Lustigman S, Bottazzi ME. Human anthelminthic vaccines: Rationale and challenges. Vaccine. PMID 27171753 DOI: 10.1016/J.Vaccine.2016.03.112 |
0.317 |
|
| 2016 |
Hotez PJ, Beaumier CM, Gillespie PM, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent hookworm disease and anemia. Vaccine. PMID 27040400 DOI: 10.1016/j.vaccine.2016.03.078 |
0.33 |
|
| 2016 |
Bartsch SM, Hotez PJ, Hertenstein DL, Diemert DJ, Zapf KM, Bottazzi ME, Bethony JM, Brown ST, Lee BY. Modeling the economic and epidemiologic impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting. Vaccine. PMID 27002501 DOI: 10.1016/J.Vaccine.2016.03.018 |
0.41 |
|
| 2015 |
Zhan B, Ajmera R, Geiger S, Gonçalves MT, Liu Z, Wei J, Wilkins PP, Fujiwara R, Gazzinelli-Guimaraes PH, Bottazzi ME, Hotez P. Identification of Immunodominant Antigens for the Laboratory Diagnosis of Toxocariasis. Tropical Medicine & International Health : Tm & Ih. PMID 26426162 DOI: 10.1111/Tmi.12607 |
0.384 |
|
| 2015 |
Hotez PJ, Bottazzi ME, Strych U. New Vaccines for the World's Poorest People. Annual Review of Medicine. PMID 26356803 DOI: 10.1146/annurev-med-051214-024241 |
0.303 |
|
| 2015 |
Pearson MS, Jariwala AR, Abbenante G, Plieskatt J, Wilson D, Bottazzi ME, Hotez PJ, Keegan B, Bethony JM, Loukas A. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74. Human Vaccines & Immunotherapeutics. 11: 1251-7. PMID 26018444 DOI: 10.4161/21645515.2014.980199 |
0.339 |
|
| 2015 |
Seid CA, Curti E, Jones RM, Hudspeth E, Rezende W, Pollet J, Center L, Versteeg L, Pritchard S, Musiychuk K, Yusibov V, Hotez PJ, Bottazzi ME. Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine. Human Vaccines & Immunotherapeutics. 11: 1474-88. PMID 25905574 DOI: 10.1080/21645515.2015.1036207 |
0.366 |
|
| 2015 |
Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YA, Goodenow MM, AbuBakar S. Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): overview and update. Plos Neglected Tropical Diseases. 9: e0003575. PMID 25880767 DOI: 10.1371/journal.pntd.0003575 |
0.31 |
|
| 2014 |
Hotez P. Tropical Medicine in the Horse Latitudes. Current Tropical Medicine Reports. 1: 3-5. PMID 32226713 DOI: 10.1007/S40475-013-0003-6 |
0.336 |
|
| 2014 |
Curti E, Seid CA, Hudspeth E, Center L, Rezende W, Pollet J, Kwityn C, Hammond M, Matsunami RK, Engler DA, Hotez PJ, Elena Bottazzi M. Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate. Human Vaccines & Immunotherapeutics. 10: 1914-25. PMID 25424799 DOI: 10.4161/hv.28872 |
0.411 |
|
| 2014 |
Ndeffo Mbah ML, Skrip L, Greenhalgh S, Hotez P, Galvani AP. Impact of Schistosoma mansoni on malaria transmission in Sub-Saharan Africa. Plos Neglected Tropical Diseases. 8: e3234. PMID 25329403 DOI: 10.1371/Journal.Pntd.0003234 |
0.376 |
|
| 2014 |
Knight JM, Zingales B, Bottazzi ME, Hotez P, Zhan B. Limited antigenic variation in the Trypanosoma cruzi candidate vaccine antigen TSA-1. Parasite Immunology. 36: 708-12. PMID 25040249 DOI: 10.1111/Pim.12130 |
0.365 |
|
| 2014 |
Hotez P, Whitham M. Helminth infections: a new global women's health agenda. Obstetrics and Gynecology. 123: 155-60. PMID 24463676 DOI: 10.1097/Aog.0000000000000025 |
0.313 |
|
| 2014 |
Tang YT, Gao X, Rosa BA, Abubucker S, Hallsworth-Pepin K, Martin J, Tyagi R, Heizer E, Zhang X, Bhonagiri-Palsikar V, Minx P, Warren WC, Wang Q, Zhan B, Hotez PJ, et al. Genome of the human hookworm Necator americanus. Nature Genetics. 46: 261-269. PMID 24441737 DOI: 10.1038/ng.2875 |
0.667 |
|
| 2014 |
Zhan B, Beaumier CM, Briggs N, Jones KM, Keegan BP, Bottazzi ME, Hotez PJ. Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections. Expert Review of Vaccines. 13: 321-31. PMID 24392641 DOI: 10.1586/14760584.2014.872035 |
0.337 |
|
| 2013 |
Hotez PJ, Diemert D, Bacon KM, Beaumier C, Bethony JM, Bottazzi ME, Brooker S, Couto AR, Freire Mda S, Homma A, Lee BY, Loukas A, Loblack M, Morel CM, Oliveira RC, et al. The Human Hookworm Vaccine. Vaccine. 31: B227-32. PMID 23598487 DOI: 10.1016/J.Vaccine.2012.11.034 |
0.313 |
|
| 2012 |
Pearson MS, Tribolet L, Cantacessi C, Periago MV, Valero MA, Valerio MA, Jariwala AR, Hotez P, Diemert D, Loukas A, Bethony J. Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. The Journal of Allergy and Clinical Immunology. 130: 13-21. PMID 22742835 DOI: 10.1016/J.Jaci.2012.05.029 |
0.37 |
|
| 2012 |
Diemert DJ, Pinto AG, Freire J, Jariwala A, Santiago H, Hamilton RG, Periago MV, Loukas A, Tribolet L, Mulvenna J, Correa-Oliveira R, Hotez PJ, Bethony JM. Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. The Journal of Allergy and Clinical Immunology. 130: 169-76.e6. PMID 22633322 DOI: 10.1016/J.Jaci.2012.04.027 |
0.364 |
|
| 2012 |
Goud GN, Deumic V, Gupta R, Brelsford J, Zhan B, Gillespie P, Plieskatt JL, Tsao EI, Hotez PJ, Bottazzi ME. Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expression and Purification. 83: 145-51. PMID 22503665 DOI: 10.1016/j.pep.2012.03.013 |
0.376 |
|
| 2012 |
Plieskatt JL, Rezende WC, Olsen CM, Trefethen JM, Joshi SB, Middaugh CR, Hotez PJ, Bottazzi ME. Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies. Human Vaccines & Immunotherapeutics. 8: 765-76. PMID 22495115 DOI: 10.4161/hv.19726 |
0.367 |
|
| 2012 |
Mathias DK, Plieskatt JL, Armistead JS, Bethony JM, Abdul-Majid KB, McMillan A, Angov E, Aryee MJ, Zhan B, Gillespie P, Keegan B, Jariwala AR, Rezende W, Bottazzi ME, Scorpio DG, ... Hotez PJ, et al. Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine. Infection and Immunity. 80: 1606-14. PMID 22311924 DOI: 10.1128/Iai.06212-11 |
0.322 |
|
| 2012 |
Xue J, Zhan B, Guo J, He N, Qiang HQ, Hotez P, Xiao SH. Acquired hookworm immunity in the golden hamster (Mesocricetus auratus) elicited by living Necator americanus third-stage infective larvae. Experimental Parasitology. 130: 6-12. PMID 22024448 DOI: 10.1016/J.Exppara.2011.10.007 |
0.397 |
|
| 2012 |
Hotez PJ, Gilman RH. Hookworm and Strongyloides Infections Hunter's Tropical Medicine and Emerging Infectious Disease: Ninth Edition. 808-813. DOI: 10.1016/B978-1-4160-4390-4.00109-0 |
0.399 |
|
| 2011 |
Hotez P. Enlarging the "Audacious Goal": elimination of the world's high prevalence neglected tropical diseases. Vaccine. 29: D104-10. PMID 22188933 DOI: 10.1016/J.Vaccine.2011.06.024 |
0.335 |
|
| 2011 |
Schneider B, Jariwala AR, Periago MV, Gazzinelli MF, Bose SN, Hotez PJ, Diemert DJ, Bethony JM. A history of hookworm vaccine development. Human Vaccines. 7: 1234-44. PMID 22064562 DOI: 10.4161/Hv.7.11.18443 |
0.371 |
|
| 2011 |
Loukas A, Gaze S, Mulvenna JP, Gasser RB, Brindley PJ, Doolan DL, Bethony JM, Jones MK, Gobert GN, Driguez P, McManus DP, Hotez PJ. Vaccinomics for the major blood feeding helminths of humans. Omics : a Journal of Integrative Biology. 15: 567-77. PMID 21679087 DOI: 10.1089/Omi.2010.0150 |
0.312 |
|
| 2011 |
Hotez P. A handful of 'antipoverty' vaccines exist for neglected diseases, but the world's poorest billion people need more. Health Affairs (Project Hope). 30: 1080-7. PMID 21653960 DOI: 10.1377/Hlthaff.2011.0317 |
0.39 |
|
| 2011 |
Alexander N, Cundill B, Sabatelli L, Bethony JM, Diemert D, Hotez P, Smith PG, Rodrigues LC, Brooker S. Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths. Vaccine. 29: 3686-94. PMID 21435404 DOI: 10.1016/J.Vaccine.2011.03.026 |
0.397 |
|
| 2011 |
Jiang D, Zhan B, Mayor RS, Gillespie P, Keegan B, Bottazzi ME, Hotez P. Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 177: 42-8. PMID 21251931 DOI: 10.1016/J.Molbiopara.2011.01.008 |
0.325 |
|
| 2011 |
Hotez PJ. Hookworm Infections Tropical Infectious Diseases. 799-804. DOI: 10.1016/B978-0-7020-3935-5.00116-6 |
0.398 |
|
| 2010 |
Hotez PJ, Bethony JM, Diemert DJ, Pearson M, Loukas A. Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nature Reviews. Microbiology. 8: 814-26. PMID 20948553 DOI: 10.1038/Nrmicro2438 |
0.346 |
|
| 2010 |
Jariwala AR, Oliveira LM, Diemert DJ, Keegan B, Plieskatt JL, Periago MV, Bottazzi ME, Hotez PJ, Bethony JM. Potency testing for the experimental Na-GST-1 hookworm vaccine. Expert Review of Vaccines. 9: 1219-30. PMID 20923271 DOI: 10.1586/Erv.10.107 |
0.41 |
|
| 2010 |
Hotez P, Stillwaggon E, McDonald M, Todman L, DiGrazia L. National summit on neglected infections of poverty in the United States. Emerging Infectious Diseases. 16: e1. PMID 20409362 DOI: 10.3201/Eid1605.091863 |
0.407 |
|
| 2010 |
Pearson MS, Pickering DA, Tribolet L, Cooper L, Mulvenna J, Oliveira LM, Bethony JM, Hotez PJ, Loukas A. Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis. The Journal of Infectious Diseases. 201: 1561-9. PMID 20367477 DOI: 10.1086/651953 |
0.378 |
|
| 2010 |
Zhan B, Perally S, Brophy PM, Xue J, Goud G, Liu S, Deumic V, de Oliveira LM, Bethony J, Bottazzi ME, Jiang D, Gillespie P, Xiao SH, Gupta R, Loukas A, ... ... Hotez P, et al. Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infection and Immunity. 78: 1552-63. PMID 20145100 DOI: 10.1128/Iai.00848-09 |
0.389 |
|
| 2010 |
Asojo OA, Goud GN, Zhan B, Ordonez K, Sedlacek M, Homma K, Deumic V, Gupta R, Brelsford J, Price MK, Ngamelue MN, Hotez PJ. Crystallization and preliminary X-ray analysis of Na-SAA-2 from the human hookworm parasite Necator americanus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 172-6. PMID 20124715 DOI: 10.1107/S1744309109051616 |
0.373 |
|
| 2010 |
Basavaraju SV, Zhan B, Kennedy MW, Liu Y, Hawdon J, Hotez PJ. Corrigendum to “Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: Gene transcription pattern, ligand binding properties and structural characterization” [Mol. Biochem. Parasitol. 126 (1) (2003) 63–71] Molecular and Biochemical Parasitology. 173: 175. DOI: 10.1016/J.Molbiopara.2010.06.001 |
0.644 |
|
| 2009 |
Hotez P. Neglected diseases amid wealth in the United States and Europe. Health Affairs (Project Hope). 28: 1720-5. PMID 19887412 DOI: 10.1377/Hlthaff.28.6.1720 |
0.335 |
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| 2009 |
Andrus JK, de Quadros C, Matus CR, Luciani S, Hotez P. New vaccines for developing countries: will it be feast or famine? American Journal of Law & Medicine. 35: 311-22. PMID 19697751 DOI: 10.1177/009885880903500204 |
0.38 |
|
| 2009 |
Ranjit N, Zhan B, Hamilton B, Stenzel D, Lowther J, Pearson M, Gorman J, Hotez P, Loukas A. Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus. The Journal of Infectious Diseases. 199: 904-12. PMID 19434933 DOI: 10.1086/597048 |
0.344 |
|
| 2009 |
Pearson MS, Bethony JM, Pickering DA, de Oliveira LM, Jariwala A, Santiago H, Miles AP, Zhan B, Jiang D, Ranjit N, Mulvenna J, Tribolet L, Plieskatt J, Smith T, Bottazzi ME, ... ... Hotez PJ, et al. An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3007-19. PMID 19380510 DOI: 10.1096/Fj.09-131433 |
0.319 |
|
| 2008 |
Brooker S, Hotez PJ, Bundy DA. Hookworm-related anaemia among pregnant women: a systematic review. Plos Neglected Tropical Diseases. 2: e291. PMID 18820740 DOI: 10.1371/journal.pntd.0000291 |
0.278 |
|
| 2008 |
Zhan B, Gupta R, Wong SP, Bier S, Jiang D, Goud G, Hotez P. Molecular cloning and characterization of Ac-TMP-2, a tissue inhibitor of metalloproteinase secreted by adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 162: 142-8. PMID 18804124 DOI: 10.1016/J.Molbiopara.2008.08.008 |
0.394 |
|
| 2008 |
Hotez PJ, Bethony JM, Oliveira SC, Brindley PJ, Loukas A. Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Review of Vaccines. 7: 745-52. PMID 18665774 DOI: 10.1586/14760584.7.6.745 |
0.371 |
|
| 2008 |
Ranjit N, Zhan B, Stenzel DJ, Mulvenna J, Fujiwara R, Hotez PJ, Loukas A. A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Molecular and Biochemical Parasitology. 160: 90-9. PMID 18501979 DOI: 10.1016/j.molbiopara.2008.04.008 |
0.359 |
|
| 2008 |
Bethony JM, Simon G, Diemert DJ, Parenti D, Desrosiers A, Schuck S, Fujiwara R, Santiago H, Hotez PJ. Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine. 26: 2408-17. PMID 18396361 DOI: 10.1016/J.Vaccine.2008.02.049 |
0.382 |
|
| 2008 |
Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the great neglected tropical diseases. The Journal of Clinical Investigation. 118: 1311-21. PMID 18382743 DOI: 10.1172/Jci34261 |
0.316 |
|
| 2008 |
Sabatelli L, Ghani AC, Rodrigues LC, Hotez PJ, Brooker S. Modelling heterogeneity and the impact of chemotherapy and vaccination against human hookworm. Journal of the Royal Society, Interface / the Royal Society. 5: 1329-41. PMID 18331978 DOI: 10.1098/rsif.2007.1255 |
0.409 |
|
| 2008 |
Diemert DJ, Bethony JM, Hotez PJ. Hookworm vaccines. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 46: 282-8. PMID 18171264 DOI: 10.1086/524070 |
0.367 |
|
| 2008 |
Mendez S, D' Samuel A, Antoine AD, Ahn S, Hotez P. Use of the air pouch model to investigate immune responses to a hookworm vaccine containing the Na-ASP-2 protein in rats. Parasite Immunology. 30: 53-6. PMID 18086017 DOI: 10.1111/J.1365-3024.2007.00994.X |
0.367 |
|
| 2008 |
Hotez P. Hookworm and poverty. Annals of the New York Academy of Sciences. 1136: 38-44. PMID 17954674 DOI: 10.1196/Annals.1425.000 |
0.392 |
|
| 2008 |
Xiao S, Zhan B, Xue J, Goud GN, Loukas A, Liu Y, Williamson A, Liu S, Deumic V, Hotez P. The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus. Experimental Parasitology. 118: 32-40. PMID 17645877 DOI: 10.1016/J.Exppara.2007.05.010 |
0.435 |
|
| 2007 |
Hotez P. A new voice for the poor. Plos Neglected Tropical Diseases. 1: e77. PMID 17989790 DOI: 10.1371/Journal.Pntd.0000077 |
0.308 |
|
| 2007 |
Inan M, Fanders SA, Zhang W, Hotez PJ, Zhan B, Meagher MM. Saturation of the secretory pathway by overexpression of a hookworm (Necator americanus) Protein (Na-ASP1). Methods in Molecular Biology (Clifton, N.J.). 389: 65-76. PMID 17951635 DOI: 10.1007/978-1-59745-456-8_5 |
0.405 |
|
| 2007 |
Asojo OA, Homma K, Sedlacek M, Ngamelue M, Goud GN, Zhan B, Deumic V, Asojo O, Hotez PJ. X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus. Bmc Structural Biology. 7: 42. PMID 17594497 DOI: 10.1186/1472-6807-7-42 |
0.364 |
|
| 2007 |
Feng J, Zhan B, Liu Y, Liu S, Williamson A, Goud G, Loukas A, Hotez P. Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 152: 132-8. PMID 17280728 DOI: 10.1016/J.Molbiopara.2007.01.001 |
0.338 |
|
| 2007 |
Fujiwara RT, Zhan B, Mendez S, Loukas A, Bueno LL, Wang Y, Plieskatt J, Oksov Y, Lustigman S, Bottazzi ME, Hotez P, Bethony JM. Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16. Clinical and Vaccine Immunology : Cvi. 14: 281-7. PMID 17267592 DOI: 10.1128/Cvi.00404-06 |
0.487 |
|
| 2007 |
Brooker S, Jardim-Botelho A, Quinnell RJ, Geiger SM, Caldas IR, Fleming F, Hotez PJ, Correa-Oliveira R, Rodrigues LC, Bethony JM. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene. 101: 146-54. PMID 17027054 DOI: 10.1016/J.Trstmh.2006.05.012 |
0.318 |
|
| 2007 |
Patel J, Hotez P, Dharajiya N, Sur S. Hookworm Protein Necator Americanus-Ancyclostoma Secreted Protein 2 (Na-Asp-2) Inhibits Allergic Airway Inflammation Journal of Allergy and Clinical Immunology. 119: S133. DOI: 10.1016/j.jaci.2006.11.649 |
0.271 |
|
| 2006 |
Jian X, Jun-Min Y, Hai-Chou X, Hui-Qing Q, Hai-Nan R, Hotez P, Bin Z, Shu-Hua X. Protective immunity elicited by ultraviolet-irradiated third-stage infective hookworm (Necator americanus and Ancylostoma caninum) larvae in mice and hamsters. The Southeast Asian Journal of Tropical Medicine and Public Health. 37: 885-95. PMID 17333729 |
0.366 |
|
| 2006 |
Bethony JM, Loukas A, Hotez PJ, Knox DP. Vaccines against blood-feeding nematodes of humans and livestock. Parasitology. 133: S63-79. PMID 17274849 DOI: 10.1017/S0031182006001818 |
0.331 |
|
| 2006 |
Brooker S, Clements AC, Hotez PJ, Hay SI, Tatem AJ, Bundy DA, Snow RW. The co-distribution of Plasmodium falciparum and hookworm among African schoolchildren. Malaria Journal. 5: 99. PMID 17083720 DOI: 10.1186/1475-2875-5-99 |
0.396 |
|
| 2006 |
Loukas A, Bethony J, Brooker S, Hotez P. Hookworm vaccines: past, present, and future. The Lancet. Infectious Diseases. 6: 733-41. PMID 17067922 DOI: 10.1016/S1473-3099(06)70630-2 |
0.45 |
|
| 2006 |
Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Diemert D, Loukas A. New technologies for the control of human hookworm infection. Trends in Parasitology. 22: 327-31. PMID 16709466 DOI: 10.1016/J.Pt.2006.05.004 |
0.36 |
|
| 2006 |
Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, Hotez PJ. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 367: 1521-32. PMID 16679166 DOI: 10.1016/S0140-6736(06)68653-4 |
0.342 |
|
| 2006 |
Williamson AL, Lustigman S, Oksov Y, Deumic V, Plieskatt J, Mendez S, Zhan B, Bottazzi ME, Hotez PJ, Loukas A. Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration. Infection and Immunity. 74: 961-7. PMID 16428741 DOI: 10.1128/Iai.74.2.961-967.2006 |
0.397 |
|
| 2006 |
Ghosh K, Wu W, Antoine AD, Bottazzi ME, Valenzuela JG, Hotez PJ, Mendez S. The impact of concurrent and treated Ancylostoma ceylanicum hookworm infections on the immunogenicity of a recombinant hookworm vaccine in hamsters. The Journal of Infectious Diseases. 193: 155-62. PMID 16323144 DOI: 10.1086/498528 |
0.359 |
|
| 2005 |
Fujiwara RT, Bethony J, Bueno LL, Wang Y, Ahn SY, Samuel A, Bottazzi ME, Hotez P, Mendez S. Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat. Human Vaccines. 1: 123-8. PMID 17012856 DOI: 10.4161/Hv.1.3.1924 |
0.377 |
|
| 2005 |
Asojo OA, Loukas A, Inan M, Barent R, Huang J, Plantz B, Swanson A, Gouthro M, Meagher MM, Hotez PJ. Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 391-4. PMID 16511050 DOI: 10.1107/S1744309105007748 |
0.31 |
|
| 2005 |
Loukas A, Bethony JM, Mendez S, Fujiwara RT, Goud GN, Ranjit N, Zhan B, Jones K, Bottazzi ME, Hotez PJ. Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. Plos Medicine. 2: e295. PMID 16231975 DOI: 10.1371/Journal.Pmed.0020295 |
0.409 |
|
| 2005 |
Xue J, Hui-Qing Q, Jun-Ming Y, Fujiwara R, Zhan B, Hotez P, Shu-Hua X. Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs. Experimental Parasitology. 111: 219-23. PMID 16198341 DOI: 10.1016/J.Exppara.2005.08.002 |
0.363 |
|
| 2005 |
Zhan B, Liu S, Perally S, Xue J, Fujiwara R, Brophy P, Xiao S, Liu Y, Feng J, Williamson A, Wang Y, Bueno LL, Mendez S, Goud G, Bethony JM, ... ... Hotez PJ, et al. Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infection and Immunity. 73: 6903-11. PMID 16177370 DOI: 10.1128/IAI.73.10.6903-6911.2005 |
0.731 |
|
| 2005 |
Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, ... ... Hotez PJ, et al. Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine. 23: 4754-64. PMID 16054275 DOI: 10.1016/J.Vaccine.2005.04.040 |
0.401 |
|
| 2005 |
Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ. Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1743-5. PMID 16037096 DOI: 10.1096/Fj.05-3936Fje |
0.366 |
|
| 2005 |
Mendez S, Zhan B, Goud G, Ghosh K, Dobardzic A, Wu W, Liu S, Deumic V, Dobardzic R, Liu Y, Bethony J, Hotez PJ. Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine. 23: 3123-30. PMID 15837211 DOI: 10.1016/J.Vaccine.2004.12.022 |
0.309 |
|
| 2005 |
Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Buss P. Hookworm: "the great infection of mankind". Plos Medicine. 2: e67. PMID 15783256 DOI: 10.1371/Journal.Pmed.0020067 |
0.413 |
|
| 2005 |
Asojo OA, Goud G, Dhar K, Loukas A, Zhan B, Deumic V, Liu S, Borgstahl GE, Hotez PJ. X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. Journal of Molecular Biology. 346: 801-14. PMID 15713464 DOI: 10.1016/j.jmb.2004.12.023 |
0.366 |
|
| 2005 |
Brooker S, Bethony JM, Rodrigues LC, Alexander N, Geiger SM, Hotez PJ. Epidemiologic, immunologic and practical considerations in developing and evaluating a human hookworm vaccine Expert Review of Vaccines. 4: 35-50. DOI: 10.1586/14760584.4.1.35 |
0.403 |
|
| 2004 |
Brooker S, Bethony J, Hotez PJ. Human hookworm infection in the 21st century. Advances in Parasitology. 58: 197-288. PMID 15603764 DOI: 10.1016/S0065-308X(04)58004-1 |
0.333 |
|
| 2004 |
Hotez PJ, Brooker S, Bethony JM, Bottazzi ME, Loukas A, Xiao S. Hookworm infection. The New England Journal of Medicine. 351: 799-807. PMID 15317893 DOI: 10.1056/NEJMra032492 |
0.398 |
|
| 2004 |
Zhan B, Wang Y, Liu Y, Williamson A, Loukas A, Hawdon JM, Xue HC, Xiao SH, Hotez PJ. Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum. International Journal For Parasitology. 34: 1037-45. PMID 15313130 DOI: 10.1016/j.ijpara.2004.04.015 |
0.704 |
|
| 2004 |
Don TA, Jones MK, Smyth D, O'Donoghue P, Hotez P, Loukas A. A pore-forming haemolysin from the hookworm, Ancylostoma caninum. International Journal For Parasitology. 34: 1029-35. PMID 15313129 DOI: 10.1016/J.Ijpara.2004.04.013 |
0.301 |
|
| 2004 |
Hsieh GC, Loukas A, Wahl AM, Bhatia M, Wang Y, Williamson AL, Kehn KW, Maruyama H, Hotez PJ, Leitenberg D, Bethony J, Constant SL. A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. Journal of Immunology (Baltimore, Md. : 1950). 173: 2699-704. PMID 15294988 DOI: 10.4049/Jimmunol.173.4.2699 |
0.343 |
|
| 2004 |
Williamson AL, Lecchi P, Turk BE, Choe Y, Hotez PJ, McKerrow JH, Cantley LC, Sajid M, Craik CS, Loukas A. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. The Journal of Biological Chemistry. 279: 35950-7. PMID 15199048 DOI: 10.1074/Jbc.M405842200 |
0.352 |
|
| 2004 |
Loukas A, Bethony JM, Williamson AL, Goud GN, Mendez S, Zhan B, Hawdon JM, Elena Bottazzi M, Brindley PJ, Hotez PJ. Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms. The Journal of Infectious Diseases. 189: 1952-61. PMID 15122534 DOI: 10.1086/386346 |
0.714 |
|
| 2004 |
Goud GN, Zhan B, Ghosh K, Loukas A, Hawdon J, Dobardzic A, Deumic V, Liu S, Dobardzic R, Zook BC, Jin Q, Liu Y, Hoffman L, Chung-Debose S, Patel R, ... ... Hotez PJ, et al. Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum. The Journal of Infectious Diseases. 189: 919-29. PMID 14976610 DOI: 10.1086/381901 |
0.715 |
|
| 2003 |
Jian X, Shu-Hua X, Hui-Qing Q, Sen L, Hotez P, Bing-Gui S, Hai-Chou X, Tie-Hua L, Bin Z. Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). II. Morphological development of the adult and its comparison with humans. Experimental Parasitology. 105: 192-200. PMID 14990312 DOI: 10.1016/J.Exppara.2003.12.016 |
0.418 |
|
| 2003 |
Hotez PJ, Ashcom J, Zhan B, Bethony J, Loukas A, Hawdon J, Wang Y, Jin Q, Jones KC, Dobardzic A, Dobardzic R, Bolden J, Essiet I, Brandt W, Russell PK, et al. Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae. The Journal of Parasitology. 89: 853-5. PMID 14533704 DOI: 10.1645/Ge-46R |
0.729 |
|
| 2003 |
Hotez PJ, Zhan B, Bethony JM, Loukas A, Williamson A, Goud GN, Hawdon JM, Dobardzic A, Dobardzic R, Ghosh K, Bottazzi ME, Mendez S, Zook B, Wang Y, Liu S, et al. Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative. International Journal For Parasitology. 33: 1245-58. PMID 13678639 DOI: 10.1016/s0020-7519(03)00158-9 |
0.75 |
|
| 2003 |
Jian X, Sen L, Hui-Qin Q, Hai-Nan R, Tie-Hua L, Hai-Chou X, Hotez PJ, Shu-Hua X. Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). I. Host sex-associated differences in hookworm burden and fecundity. Experimental Parasitology. 104: 62-6. PMID 12932761 |
0.315 |
|
| 2003 |
Zhan B, Liu Y, Badamchian M, Williamson A, Feng J, Loukas A, Hawdon JM, Hotez PJ. Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum. International Journal For Parasitology. 33: 897-907. PMID 12906874 DOI: 10.1016/s0020-7519(03)00111-5 |
0.683 |
|
| 2003 |
Dalton JP, Brindley PJ, Knox DP, Brady CP, Hotez PJ, Donnelly S, O'Neill SM, Mulcahy G, Loukas A. Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression. International Journal For Parasitology. 33: 621-40. PMID 12782060 DOI: 10.1016/S0020-7519(03)00057-2 |
0.314 |
|
| 2003 |
Basavaraju SV, Basavaraju S, Zhan B, Kennedy MW, Liu Y, Hawdon J, Hotez PJ. Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation. Molecular and Biochemical Parasitology. 126: 63-71. PMID 12554085 DOI: 10.1016/S0166-6851(02)00253-0 |
0.685 |
|
| 2003 |
Williamson AL, Brindley PJ, Abbenante G, Datu BJ, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Zhan B, Loukas A. Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. The Journal of Infectious Diseases. 187: 484-94. PMID 12552433 DOI: 10.1086/367708 |
0.339 |
|
| 2002 |
Bethony J, Chen J, Lin S, Xiao S, Zhan B, Li S, Xue H, Xing F, Humphries D, Yan W, Chen G, Foster V, Hawdon JM, Hotez PJ. Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 35: 1336-44. PMID 12439796 DOI: 10.1086/344268 |
0.687 |
|
| 2002 |
Williamson AL, Brindley PJ, Abbenante G, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Dalton JP, Loukas A. Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1458-60. PMID 12205047 DOI: 10.1096/Fj.02-0181Fje |
0.328 |
|
| 2002 |
Hotez PJ, Ashcom J, Bin Z, Bethony J, Williamson A, Hawdon JM, Jianjun F, Dobardzic A, Rizo I, Bolden J, Jin Q, Yan W, Dobardzic R, Chung-Debose S, Crowell M, et al. Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine. The Journal of Parasitology. 88: 684-90. PMID 12197114 DOI: 10.1645/0022-3395(2002)088[0684:EOVWRF]2.0.CO;2 |
0.721 |
|
| 2002 |
Zhan B, Badamchian M, Meihua B, Ashcom J, Feng J, Hawdon J, Shuhua X, Hotez PJ. Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms. The American Journal of Tropical Medicine and Hygiene. 66: 238-44. PMID 12139214 DOI: 10.4269/Ajtmh.2002.66.238 |
0.682 |
|
| 2002 |
Zhan B, Hotez PJ, Wang Y, Hawdon JM. A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases. Molecular and Biochemical Parasitology. 120: 291-6. PMID 11897134 DOI: 10.1016/s0166-6851(01)00453-4 |
0.691 |
|
| 2002 |
Jones BF, Hotez PJ. Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Molecular and Biochemical Parasitology. 119: 107-16. PMID 11755191 DOI: 10.1016/S0166-6851(01)00409-1 |
0.35 |
|
| 2002 |
Hotez PJ, Bin Z, Bethony J, Jin Q, Hawdon JM, Young HA, Simmens S, Hitzelberg R, Zook BC. Natural History of Primary Canine Hookworm Infections After Three Different Oral Doses of Third-Stage Infective Larvae of Ancylostoma caninum Comparative Parasitology. 69: 72-80. DOI: 10.1654/1525-2647(2002)069[0072:NHOPCH]2.0.CO;2 |
0.706 |
|
| 2002 |
Hotez PJ. China's Hookworms The China Quarterly. 172: 1029-1041. DOI: 10.1017/S0009443902000608 |
0.359 |
|
| 2001 |
Shuhua X, Hotez PJ, Binggui S, Sen L, Huiqing Q, Haichou X, Bin Z, Zheng F. Electron and light microscopy of neutrophil responses in mice vaccinated and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Parasitology International. 50: 241-8. PMID 11719110 |
0.366 |
|
| 2001 |
Gandhi NS, Jizhang C, Khoshnood K, Fuying X, Shanwen L, Yaoruo L, Bin Z, Haechou X, Chongjin T, Yan W, Wensen W, Dungxing H, Chong C, Shuhua X, Hawdon JM, ... Hotez PJ, et al. Epidemiology of Necator americanus hookworm infections in Xiulongkan Village, Hainan Province, China: high prevalence and intensity among middle-aged and elderly residents. The Journal of Parasitology. 87: 739-43. PMID 11534635 DOI: 10.1645/0022-3395(2001)087[0739:Eonahi]2.0.Co;2 |
0.704 |
|
| 2000 |
Zhan B, Hawdon J, Shan Q, Ren H, Qiang H, Xiao SH, Li TH, Feng Z, Hotez P. Construction and analysis of cDNA library of Necator americanus third stage larvae. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 18: 26-8. PMID 12567467 |
0.64 |
|
| 2000 |
Lili Z, Bingxiang Z, Hong T, Shuhua X, Hotez P, Bing Z, Yangzhong L, Ying L, Haichou X, Hawdon J, Hui Y, Huizhen W, Zhen F. Epidemiology of human geohelminth infections (ascariasis, trichuriasis and necatoriasis) in Lushui and Puer Counties, Yunnan Province, China. The Southeast Asian Journal of Tropical Medicine and Public Health. 31: 448-53. PMID 11288999 |
0.717 |
|
| 2000 |
Qiang S, Bin Z, Shu-hua X, Zheng F, Hotez P, Hawdon JM. Variation between ASP-1 molecules from Ancylostoma caninum in China and the United States. The Journal of Parasitology. 86: 181-5. PMID 10701589 DOI: 10.1645/0022-3395(2000)086[0181:Vbamfa]2.0.Co;2 |
0.726 |
|
| 2000 |
Tissenbaum HA, Hawdon J, Perregaux M, Hotez P, Guarente L, Ruvkun G. A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum. Proceedings of the National Academy of Sciences of the United States of America. 97: 460-5. PMID 10618440 DOI: 10.1073/Pnas.97.1.460 |
0.675 |
|
| 2000 |
Sen L, Ghosh K, Bin Z, Qiang S, Thompson MG, Hawdon JM, Koski RA, Shuhua X, Hotez PJ. Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus. Vaccine. 18: 1096-102. PMID 10590331 DOI: 10.1016/S0264-410X(99)00371-0 |
0.721 |
|
| 2000 |
Hotez PJ. Pediatric geohelminth infections: Trichuriasis, ascariasis, and hookworm infections Seminars in Pediatric Infectious Diseases. 11: 236-244. DOI: 10.1053/spid.2000.9637 |
0.398 |
|
| 2000 |
Hotez P. The other intestinal protozoa: Enteric infections caused by Blastocystis hominis, Entamoeba coli, and Dientamoeba fragilis Seminars in Pediatric Infectious Diseases. 11: 178-181. DOI: 10.1053/Pi.2000.6228 |
0.355 |
|
| 1999 |
Li T, Zhan B, Hawdon JM, Gong X, Xiao S, Shan Q, Feng Z, Hotez PJ. [Sequencing of cytochrome C oxidase 1 gene of Ancylostoma duodenale and Necator americanus]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 17: 81-3. PMID 12563786 |
0.633 |
|
| 1999 |
Yang Y, Xiao S, Ren H, Wu J, Feng Z, Hotez PJ. Cutaneous and subcutaneous mast cell and eosinophil responses after challenge in mice vaccinated with living infective third-stage hookworm larvae. Chinese Medical Journal. 112: 1020-3. PMID 11721464 |
0.418 |
|
| 1999 |
Xiao S, Ren H, Yang Y, Liu S, Qiang H, Xue H, Feng Z, Hotez PJ. Length of protection by murine vaccination with living infective third-stage hookworm larvae. Chinese Medical Journal. 112: 1129-32. PMID 11721454 |
0.425 |
|
| 1999 |
Xue H, Liu S, Ren H, Qiang H, Xiao S, Feng Z, Hotez P. Enzyme-linked immunoelectrotransfer blotting analysis of human serologic responses to infective hookworm larval antigen. Chinese Medical Journal. 112: 249-50. PMID 11593560 |
0.396 |
|
| 1999 |
Yong W, Guangjin S, Weitu W, Shuhua X, Hotez PJ, Qiyang L, Haichou X, Xiaomei Y, Xiaoming L, Bin Z, Hawdon JM, Li C, Hong J, Chunmei H, Zheng F. Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou village), Anhui Province, China: age-associated prevalence, intensity and hookworm species identification. The Southeast Asian Journal of Tropical Medicine and Public Health. 30: 692-7. PMID 10928362 |
0.726 |
|
| 1999 |
Yuanqing Y, Shuhua X, Hotez PJ, Jiadong W. Histochemical alterations of infective third-stage hookworm larvae (L3) in vaccinated mice. The Southeast Asian Journal of Tropical Medicine and Public Health. 30: 356-64. PMID 10774709 |
0.369 |
|
| 1999 |
Hotez PJ, Ghosh K, Hawdon JM, Narasimhan S, Jones B, Shuhua X, Sen L, Bin Z, Haechou X, Hainan R, Heng W, Koski RA. Experimental approaches to the development of a recombinant hookworm vaccine. Immunological Reviews. 171: 163-71. PMID 10582170 DOI: 10.1111/j.1600-065X.1999.tb01347.x |
0.774 |
|
| 1999 |
Changhua L, Xiaorong Z, Dongchuan Q, Shuhua X, Hotez PJ, Defu Z, Hulian Z, Mingden L, Hainan R, Bing Z, Haichou X, Hawdon J, Zheng F. Epidemiology of human hookworm infections among adult villagers in Hejiang and Santai Counties, Sichuan Province, China. Acta Tropica. 73: 243-9. PMID 10546842 DOI: 10.1016/S0001-706X(99)00035-2 |
0.74 |
|
| 1999 |
Ghosh K, Hotez PJ. Antibody-dependent reductions in mouse hookworm burden after vaccination with Ancylostoma caninum secreted protein 1. The Journal of Infectious Diseases. 180: 1674-81. PMID 10515831 DOI: 10.1086/315059 |
0.42 |
|
| 1999 |
Labiano-Abello N, Canese J, Velazquez ME, Hawdon JM, Wilson ML, Hotez PJ. Epidemiology of hookworm infection in Itagua, Paraguay: a cross sectional study. Memã³Rias Do Instituto Oswaldo Cruz. 94: 583-6. PMID 10464397 DOI: 10.1590/S0074-02761999000500003 |
0.732 |
|
| 1999 |
Hawdon JM, Narasimhan S, Hotez PJ. Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum. Molecular and Biochemical Parasitology. 99: 149-65. PMID 10340481 DOI: 10.1016/S0166-6851(99)00011-0 |
0.72 |
|
| 1999 |
Bin Z, Hawdon J, Qiang S, Hainan R, Huiqing Q, Wei H, Shu-Hua X, Tiehua L, Xing G, Zheng F, Hotez P. Ancylostoma secreted protein 1 (ASP-1) homologues in human hookworms. Molecular and Biochemical Parasitology. 98: 143-9. PMID 10029316 DOI: 10.1016/S0166-6851(98)00157-1 |
0.702 |
|
| 1998 |
Fenghua S, Zhongxing W, Yixing Q, Hangqun C, Haichou X, Hainan R, Shuhua X, Bin Z, Hawdon JM, Zheng F, Hotez PJ. Epidemiology of human intestinal nematode infections in Wujiang and Pizhou counties, Jiangsu Province, China. The Southeast Asian Journal of Tropical Medicine and Public Health. 29: 605-10. PMID 10437966 |
0.727 |
|
| 1998 |
Xiao S, Ren H, Yang Y, Xue H, Qiang H, Liu S, Feng Z, Hotez PJ. Protective immunity in mice elicited by living infective third-stage hookworm larvae (Shanghai strain of Ancylostoma caninum). Chinese Medical Journal. 111: 43-8. PMID 10322652 |
0.372 |
|
| 1998 |
Shuhua X, Hotez PJ, Binggui S, Sen L, Hainan R, Haichou X, Huiqing Q, Zheng F. Electron and light microscopy of peritoneal cellular immune responses in mice vaccinated and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Acta Tropica. 71: 155-67. PMID 9821464 |
0.311 |
|
| 1998 |
Yang Y, Xiau S, Ren H, Wu J, Hotez PJ. Cutaneous and subcutaneous granulomata formation in mice immunized and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Acta Tropica. 69: 229-38. PMID 9638275 |
0.324 |
|
| 1998 |
Zhan B, Hawdon J, Shan Q, Ren H, Qiang H, Gong X, Xiao S, Hotez P. Screening and sequential comparison of Ancylostoma-secreted protein 1 and 2 (ASP1, ASP2) genes from different species of hookworm Parasitology International. 47: 213. DOI: 10.1016/S1383-5769(98)80563-1 |
0.368 |
|
| 1997 |
Hotez PJ, Ghosh K, Hawdon J, Narasimhan S, Jones B, Bethony J. Vaccines for hookworm infection. The Pediatric Infectious Disease Journal. 16: 935-40. PMID 9380467 DOI: 10.1097/00006454-199710000-00006 |
0.746 |
|
| 1996 |
Ghosh K, Hawdon J, Hotez P. Vaccination with alum-precipitated recombinant Ancylostoma-secreted protein 1 protects mice against challenge infections with infective hookworm (Ancylostoma caninum) larvae. The Journal of Infectious Diseases. 174: 1380-3. PMID 8940240 DOI: 10.1093/Infdis/174.6.1380 |
0.764 |
|
| 1996 |
Hawdon JM, Hotez PJ. Hookworm: developmental biology of the infectious process. Current Opinion in Genetics & Development. 6: 618-23. PMID 8939719 DOI: 10.1016/S0959-437X(96)80092-X |
0.724 |
|
| 1996 |
Hotez PJ, Hawdon JM, Cappello M, Jones BF, Ghosh K, Volvovitz F, Xiao SH. Molecular approaches to vaccinating against hookworm disease. Pediatric Research. 40: 515-21. PMID 8888276 DOI: 10.1203/00006450-199610000-00001 |
0.745 |
|
| 1996 |
Cappello M, Hawdon JM, Jones BF, Kennedy WP, Hotez PJ. Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli. Molecular and Biochemical Parasitology. 80: 113-7. PMID 8885227 DOI: 10.1016/0166-6851(96)02658-8 |
0.674 |
|
| 1996 |
Stanssens P, Bergum PW, Gansemans Y, Jespers L, Laroche Y, Huang S, Maki S, Messens J, Lauwereys M, Cappello M, Hotez PJ, Lasters I, Vlasuk GP. Anticoagulant repertoire of the hookworm Ancylostoma caninum Proceedings of the National Academy of Sciences of the United States of America. 93: 2149-2154. PMID 8700900 DOI: 10.1073/pnas.93.5.2149 |
0.333 |
|
| 1996 |
Hawdon JM, Jones BF, Hoffman DR, Hotez PJ. Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae. The Journal of Biological Chemistry. 271: 6672-8. PMID 8636085 DOI: 10.1074/Jbc.271.12.6672 |
0.733 |
|
| 1996 |
HOFFMAN D, HAWDON J, JONES B, HOTEZ P. 126 Helminth secretory proteins are related to wasp antigen 5 by both sequence and immunologic cross-reactivity Journal of Allergy and Clinical Immunology. 97: 214-214. DOI: 10.1016/S0091-6749(96)80344-7 |
0.667 |
|
| 1995 |
Hawdon JM, Jones BF, Perregaux MA, Hotez PJ. Ancylostoma caninum: metalloprotease release coincides with activation of infective larvae in vitro. Experimental Parasitology. 80: 205-11. PMID 7895832 DOI: 10.1006/Expr.1995.1025 |
0.703 |
|
| 1995 |
Hawdon JM, Jones BF, Hotez PJ. Cloning and characterization of a cDNA encoding the catalytic subunit of a cAMP-dependent protein kinase from Ancylostoma caninum third-stage infective larvae. Molecular and Biochemical Parasitology. 69: 127-30. PMID 7723782 DOI: 10.1016/0166-6851(94)00203-Y |
0.699 |
|
| 1995 |
Hotez PJ, Hawdon JM, Cappello M, Jones BF, Pritchard DI. Molecular pathobiology of hookworm infection. Infectious Agents and Disease. 4: 71-5. PMID 7613730 |
0.731 |
|
| 1995 |
Cappello M, Vlasuk GP, Bergum PW, Huang S, Hotez PJ. Ancylostoma caninum anticoagulant peptide: A hookworm-derived inhibitor of human coagulation factor Xa Proceedings of the National Academy of Sciences of the United States of America. 92: 6152-6156. PMID 7597095 DOI: 10.1073/pnas.92.13.6152 |
0.313 |
|
| 1994 |
Hotez P, Cappello M, Hawdon J, Beckers C, Sakanari J. Hyaluronidases of the gastrointestinal invasive nematodes Ancylostoma caninum and Anisakis simplex: Possible functions in the pathogenesis of human zoonoses Journal of Infectious Diseases. 170: 918-926. PMID 7930737 DOI: 10.1093/Infdis/170.4.918 |
0.689 |
|
| 1993 |
Hotez P, Hawdon J, Schad GA. Hookworm larval infectivity, arrest and amphiparatenesis: the Caenorhabditis elegans Daf-c paradigm. Parasitology Today (Personal Ed.). 9: 23-6. PMID 15463660 DOI: 10.1016/0169-4758(93)90159-D |
0.784 |
|
| 1993 |
Cappello M, Clyne LP, McPhedran P, Hotez PJ. Ancylostoma Factor Xa Inhibitor: Partial Purification and Its Identification as a Major Hookworm-Derived Anticoagulant In Vitro Journal of Infectious Diseases. 167: 1474-1477. PMID 8501344 DOI: 10.1093/infdis/167.6.1474 |
0.267 |
|
| 1992 |
Hotez PJ, Narasimhan S, Haggerty J, Milstone L, Bhopale V, Schad GA, Richards FF. Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans. Infection and Immunity. 60: 1018-23. PMID 1541516 DOI: 10.1128/Iai.60.3.1018-1023.1992 |
0.608 |
|
| 1990 |
Hotez P, Haggerty J, Hawdon J, Milstone L, Gamble HR, Schad G, Richards F. Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis Infection and Immunity. 58: 3883-3892. PMID 2254016 DOI: 10.1128/Iai.58.12.3883-3892.1990 |
0.772 |
|
| 1990 |
Hotez P, Haggerty J, Hawdon J, Milstone L, Gamble HR, Schad G, Richards F. Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis. Infection and Immunity. 58: 3883-3892. DOI: 10.1128/iai.58.12.3883-3892.1990 |
0.766 |
|
| 1987 |
Hotez PJ, Le Trang N, Cerami A. Hookworm antigens: the potential for vaccination. Parasitology Today (Personal Ed.). 3: 247-9. PMID 15462967 DOI: 10.1016/0169-4758(87)90148-7 |
0.613 |
|
| 1985 |
Cerami A, Ikeda Y, Le Trang N, Hotez PJ, Beutler B. Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: the role of cachectin (tumor necrosis factor). Immunology Letters. 11: 173-7. PMID 3910566 DOI: 10.1016/0165-2478(85)90165-8 |
0.562 |
|
| 1985 |
Hotez PJ, Trang NL, McKerrow JH, Cerami A. Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum. The Journal of Biological Chemistry. 260: 7343-8. PMID 3888998 |
0.517 |
|
| 1984 |
Hotez PJ, Le Trang N, Fairlamb AH, Cerami A. Lipoprotein lipase suppression in 3T3-L1 cells by a haematoprotozoan-induced mediator from peritoneal exudate cells. Parasite Immunology. 6: 203-9. PMID 6377200 DOI: 10.1111/J.1365-3024.1984.Tb00793.X |
0.492 |
|
| 1983 |
Hotez PJ, Cerami A. Secretion of a proteolytic anticoagulant by Ancylostoma hookworms. The Journal of Experimental Medicine. 157: 1594-603. PMID 6343546 DOI: 10.1084/Jem.157.5.1594 |
0.478 |
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