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123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Wang Y, Su L, Morin MD, Jones BT, Whitby LR, Surakattula MM, Huang H, Shi H, Choi JH, Wang KW, Moresco EM, Berger M, Zhan X, Zhang H, Boger DL, ... Beutler B, et al. TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831104 DOI: 10.1073/Pnas.1525639113  1
2015 Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, Su L, Pratt D, Bu CH, Hildebrand S, Lyon S, Scott L, Quan J, Sun Q, Russell J, ... ... Beutler B, et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. Nature Immunology. PMID 26642356 DOI: 10.1038/Ni.3333  1
2015 Simon MM, Moresco EM, Bull KR, Kumar S, Mallon AM, Beutler B, Potter PK. Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencing. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 26449678 DOI: 10.1007/S00335-015-9603-X  1
2015 Siggs OM, Popkin DL, Krebs P, Li X, Tang M, Zhan X, Zeng M, Lin P, Xia Y, Oldstone MB, Cornall RJ, Beutler B. Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438836 DOI: 10.1073/Pnas.1515619112  1
2015 Mager LF, Riether C, Schürch CM, Banz Y, Wasmer MH, Stuber R, Theocharides AP, Li X, Xia Y, Saito H, Nakae S, Baerlocher GM, Manz MG, McCoy KD, Macpherson AJ, ... ... Beutler B, et al. IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms. The Journal of Clinical Investigation. 125: 2579-91. PMID 26011644 DOI: 10.1172/Jci77347  1
2015 von Hertzen L, Beutler B, Bienenstock J, Blaser M, Cani PD, Eriksson J, Färkkilä M, Haahtela T, Hanski I, Jenmalm MC, Kere J, Knip M, Kontula K, Koskenvuo M, Ling C, et al. Helsinki alert of biodiversity and health. Annals of Medicine. 47: 218-25. PMID 25904094 DOI: 10.3109/07853890.2015.1010226  1
2015 Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T, Wang Y, ... ... Beutler B, et al. Real-time resolution of point mutations that cause phenovariance in mice. Proceedings of the National Academy of Sciences of the United States of America. 112: E440-9. PMID 25605905 DOI: 10.1073/Pnas.1423216112  1
2015 Jiménez-Dalmaroni MJ, Radcliffe CM, Harvey DJ, Wormald MR, Verdino P, Ainge GD, Larsen DS, Painter GF, Ulevitch R, Beutler B, Rudd PM, Dwek RA, Wilson IA. Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids. Innate Immunity. 21: 175-93. PMID 24591200 DOI: 10.1177/1753425914524077  1
2014 Zeng M, Hu Z, Shi X, Li X, Zhan X, Li XD, Wang J, Choi JH, Wang KW, Purrington T, Tang M, Fina M, DeBerardinis RJ, Moresco EM, Pedersen G, ... ... Beutler B, et al. MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses. Science (New York, N.Y.). 346: 1486-92. PMID 25525240 DOI: 10.1126/Science.346.6216.1486  1
2014 Rommelaere S, Millet V, Vu Manh TP, Gensollen T, Andreoletti P, Cherkaoui-Malki M, Bourges C, Escalière B, Du X, Xia Y, Imbert J, Beutler B, Kanai Y, Malissen B, Malissen M, et al. Sox17 regulates liver lipid metabolism and adaptation to fasting. Plos One. 9: e104925. PMID 25141153 DOI: 10.1371/Journal.Pone.0104925  1
2014 Chen Z, Holland W, Shelton JM, Ali A, Zhan X, Won S, Tomisato W, Liu C, Li X, Moresco EM, Beutler B. Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 7367-72. PMID 24799716 DOI: 10.1073/Pnas.1406511111  1
2014 Garrison SR, Weyer AD, Barabas ME, Beutler BA, Stucky CL. A gain-of-function voltage-gated sodium channel 1.8 mutation drives intense hyperexcitability of A- and C-fiber neurons. Pain. 155: 896-905. PMID 24447515 DOI: 10.1016/J.Pain.2014.01.012  1
2014 Pedersen GK, Àdori M, Khoenkhoen S, Dosenovic P, Beutler B, Karlsson Hedestam GB. B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS Proceedings of the National Academy of Sciences of the United States of America. 111: E4119-E4126. DOI: 10.1073/Pnas.1415866111  1
2013 Tabeta K, Hoebe K, Janssen EM, Xia Y, Beutler B. Respond to "No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice". Nature Immunology. 14: 1102-3. PMID 24145779 DOI: 10.1038/Ni.2734  1
2013 Beutler B. The central answer. Interview by Kristie Nybo Biotechniques. 54: 241. PMID 23805428  1
2013 Moresco EM, Li X, Beutler B. Going forward with genetics: recent technological advances and forward genetics in mice. The American Journal of Pathology. 182: 1462-73. PMID 23608223 DOI: 10.1016/J.Ajpath.2013.02.002  1
2013 Koh YT, Scatizzi JC, Gahan JD, Lawson BR, Baccala R, Pollard KM, Beutler BA, Theofilopoulos AN, Kono DH. Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 4982-90. PMID 23589617 DOI: 10.4049/Jimmunol.1202986  1
2013 Teh CE, Horikawa K, Arnold CN, Beutler B, Kucharska EM, Vinuesa CG, Bertram EM, Goodnow CC, Enders A. Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation Genes and Immunity. 14: 223-233. PMID 23552399 DOI: 10.1038/Gene.2013.11  1
2013 Beutler B. Bruce Beutler wins the 2013 ASCI/Stanley J. Korsmeyer Award. Interview by Kathryn Claiborn The Journal of Clinical Investigation. 123: 1403-1404. PMID 23543061  1
2013 Beutler B. Bruce Beutler: the persistent prospector. Interview by Ruth Williams Circulation Research. 112: 751-754. PMID 23449544 DOI: 10.1161/CIRCRESAHA.113.301093  1
2013 Bull KR, Rimmer AJ, Siggs OM, Miosge LA, Roots CM, Enders A, Bertram EM, Crockford TL, Whittle B, Potter PK, Simon MM, Mallon AM, Brown SD, Beutler B, Goodnow CC, et al. Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations. Plos Genetics. 9: e1003219. PMID 23382690 DOI: 10.1371/Journal.Pgen.1003219  1
2013 Baccala R, Gonzalez-Quintial R, Blasius AL, Rimann I, Ozato K, Kono DH, Beutler B, Theofilopoulos AN. Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus. Proceedings of the National Academy of Sciences of the United States of America. 110: 2940-5. PMID 23382217 DOI: 10.1073/Pnas.1222798110  1
2013 Beutler B. The central answer Biotechniques. 54: 241. DOI: 10.2144/000114023  1
2012 Brandl K, Beutler B. Creating diseases to understand what prevents them: Genetic analysis of inflammation in the gastrointestinal tract Current Opinion in Immunology. 24: 678-685. PMID 23123276 DOI: 10.1016/J.Coi.2012.10.005  1
2012 Arnold CN, Barnes MJ, Berger M, Blasius AL, Brandl K, Croker B, Crozat K, Du X, Eidenschenk C, Georgel P, Hoebe K, Huang H, Jiang Z, Krebs P, La Vine D, ... ... Beutler B, et al. ENU-induced phenovariance in mice: inferences from 587 mutations. Bmc Research Notes. 5: 577. PMID 23095377 DOI: 10.1186/1756-0500-5-577  1
2012 Siggs OM, Beutler B. The BTB-ZF transcription factors Cell Cycle. 11: 3358-3369. PMID 22894929 DOI: 10.4161/Cc.21277  1
2012 Siggs OM, Cruite JT, Du X, Rutschmann S, Masliah E, Beutler B, Oldstone MB. Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 13733-8. PMID 22869751 DOI: 10.1073/Pnas.1211499109  1
2012 Brandl K, Tomisato W, Li X, Neppl C, Pirie E, Falk W, Xia Y, Moresco EM, Baccala R, Theofilopoulos AN, Schnabl B, Beutler B. Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 12650-5. PMID 22802641 DOI: 10.1073/Pnas.1210366109  1
2012 Arnold CN, Pirie E, Dosenovic P, McInerney GM, Xia Y, Wang N, Li X, Siggs OM, Karlsson Hedestam GB, Beutler B. A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proceedings of the National Academy of Sciences of the United States of America. 109: 12286-93. PMID 22761313 DOI: 10.1073/Pnas.1209134109  1
2012 Andrews TD, Whittle B, Field MA, Balakishnan B, Zhang Y, Shao Y, Cho V, Kirk M, Singh M, Xia Y, Hager J, Winslade S, Sjollema G, Beutler B, Enders A, et al. Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: An immediate source for thousands of new mouse models Open Biology. 2. PMID 22724066 DOI: 10.1098/Rsob.120061  1
2012 Siggs OM, Xiao N, Wang Y, Shi H, Tomisato W, Li X, Xia Y, Beutler B. iRhom2 is required for the secretion of mouse TNFα Blood. 119: 5769-5771. PMID 22550345 DOI: 10.1182/Blood-2012-03-417949  1
2012 Rutschmann S, Crozat K, Li X, Du X, Hanselman JC, Shigeoka AA, Brandl K, Popkin DL, McKay DB, Xia Y, Moresco EM, Beutler B. Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice. G3 (Bethesda, Md.). 2: 499-504. PMID 22540041 DOI: 10.1534/G3.112.002196  1
2012 Narni-Mancinelli E, Jaeger BN, Bernat C, Fenis A, Kung S, De Gassart A, Mahmood S, Gut M, Heath SC, Estellé J, Bertosio E, Vely F, Gastinel LN, Beutler B, Malissen B, et al. Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science (New York, N.Y.). 335: 344-8. PMID 22267813 DOI: 10.1126/Science.1215621  1
2012 Brandl K, Tomisato W, Beutler B. Inflammatory bowel disease and ADAM17 deletion New England Journal of Medicine. 366: 190. PMID 22236242 DOI: 10.1056/Nejmc1113859  1
2012 Won S, Eidenschenk C, Arnold CN, Siggs OM, Sun L, Brandl K, Mullen TM, Nemerow GR, Moresco EM, Beutler B. Increased susceptibility to DNA virus infection in mice with a GCN2 mutation. Journal of Virology. 86: 1802-8. PMID 22114338 DOI: 10.1128/Jvi.05660-11  1
2011 Moresco EM, Beutler B. Resisting viral infection: the gene by gene approach. Current Opinion in Virology. 1: 513-8. PMID 22440911 DOI: 10.1016/J.Coviro.2011.10.005  1
2011 Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, ... ... Beutler B, et al. Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proceedings of the National Academy of Sciences of the United States of America. 108: 19678-82. PMID 22106289 DOI: 10.1073/Pnas.1117835108  1
2011 Blasius AL, Dubin AE, Petrus MJ, Lim BK, Narezkina A, Criado JR, Wills DN, Xia Y, Moresco EM, Ehlers C, Knowlton KU, Patapoutian A, Beutler B. Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype. Proceedings of the National Academy of Sciences of the United States of America. 108: 19413-8. PMID 22087007 DOI: 10.1073/Pnas.1117020108  1
2011 Theofilopoulos AN, Kono DH, Beutler B, Baccala R. Intracellular nucleic acid sensors and autoimmunity Journal of Interferon and Cytokine Research. 31: 867-886. PMID 22029446 DOI: 10.1089/Jir.2011.0092  1
2011 Krieg L, Milstein O, Krebs P, Xia Y, Beutler B, Du X. Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron-deficiency anemia in mice Blood. 118: 6418-6425. PMID 21976678 DOI: 10.1182/Blood-2011-04-350082  1
2011 Moresco EM, Vine DL, Beutler B. Prion-like behavior of MAVS in RIG-I signaling. Cell Research. 21: 1643-5. PMID 21931357 DOI: 10.1038/Cr.2011.155  1
2011 Xia CH, Lu E, Liu H, Du X, Beutler B, Gong X. The role of Vldlr in intraretinal angiogenesis in mice. Investigative Ophthalmology & Visual Science. 52: 6572-9. PMID 21757581 DOI: 10.1167/Iovs.10-7082  1
2011 Moresco EM, LaVine D, Beutler B. Toll-like receptors. Current Biology : Cb. 21: R488-93. PMID 21741580 DOI: 10.1016/J.Cub.2011.05.039  1
2011 Eleftherianos I, Won S, Chtarbanova S, Squiban B, Ocorr K, Bodmer R, Beutler B, Hoffmann JA, Imler JL. ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections. Proceedings of the National Academy of Sciences of the United States of America. 108: 12024-9. PMID 21719711 DOI: 10.1073/Pnas.1108926108  1
2011 Zak DE, Schmitz F, Gold ES, Diercks AH, Peschon JJ, Valvo JS, Niemistö A, Podolsky I, Fallen SG, Suen R, Stolyar T, Johnson CD, Kennedy KA, Hamilton MK, Siggs OM, ... Beutler B, et al. Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses. Proceedings of the National Academy of Sciences of the United States of America. 108: 11536-41. PMID 21709223 DOI: 10.1073/Pnas.1107577108  1
2011 Krebs P, Crozat K, Popkin D, Oldstone MB, Beutler B. Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice. Blood. 117: 6582-8. PMID 21551232 DOI: 10.1182/Blood-2011-01-329607  1
2011 Siggs OM, Schnabl B, Webb B, Beutler B. X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C Proceedings of the National Academy of Sciences of the United States of America. 108: 7890-7895. PMID 21518881 DOI: 10.1073/Pnas.1104631108  1
2011 Moresco EM, Beutler B. Special delivery: granulin brings CpG DNA to Toll-like receptor 9. Immunity. 34: 453-5. PMID 21511177 DOI: 10.1016/J.Immuni.2011.04.001  1
2011 Siggs OM, Arnold CN, Huber C, Pirie E, Xia Y, Lin P, Nemazee D, Beutler B. The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow. Nature Immunology. 12: 434-40. PMID 21423172 DOI: 10.1038/Ni.2012  1
2011 Popkin DL, Teijaro JR, Sullivan BM, Urata S, Rutschmann S, de la Torre JC, Kunz S, Beutler B, Oldstone M. Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner. Cell Host & Microbe. 9: 212-22. PMID 21402360 DOI: 10.1016/J.Chom.2011.02.006  1
2011 Iavarone C, Ramsauer K, Kubarenko AV, Debasitis JC, Leykin I, Weber AN, Siggs OM, Beutler B, Zhang P, Otten G, D'Oro U, Valiante NM, Mbow ML, Visintin A. A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding. Journal of Immunology (Baltimore, Md. : 1950). 186: 4213-22. PMID 21383246 DOI: 10.4049/Jimmunol.1003585  1
2011 Beutler S, Beutler B. Ernest Beutler: His life and contribution to medical science British Journal of Haematology. 152: 543-550. PMID 21241280 DOI: 10.1111/J.1365-2141.2010.08542.X  1
2011 Crozat K, Eidenschenk C, Jaeger BN, Krebs P, Guia S, Beutler B, Vivier E, Ugolini S. Impact of β2 integrin deficiency on mouse natural killer cell development and function Blood. 117: 2874-2882. PMID 21239699 DOI: 10.1182/Blood-2010-10-315457  1
2011 Arnold CN, Xia Y, Lin P, Ross C, Schwander M, Smart NG, Müller U, Beutler B. Rapid identification of a disease allele in mouse through whole genome sequencing and bulk segregation analysis. Genetics. 187: 633-41. PMID 21196518 DOI: 10.1534/Genetics.110.124586  1
2011 Beutler B, Goodnow CC. How host defense is encoded in the mammalian genome Mammalian Genome. 22: 1-5. PMID 21184083 DOI: 10.1007/S00335-010-9312-4  1
2010 Guma M, Kashiwakura J, Crain B, Kawakami Y, Beutler B, Firestein GS, Kawakami T, Karin M, Corr M. JNK1 controls mast cell degranulation and IL-1{beta} production in inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America. 107: 22122-7. PMID 21135226 DOI: 10.1073/Pnas.1016401107  1
2010 Ronald PC, Beutler B. Plant and animal sensors of conserved microbial signatures Science. 330: 1061-1064. PMID 21097929 DOI: 10.1126/Science.1189468  1
2010 Blasius AL, Arnold CN, Georgel P, Rutschmann S, Xia Y, Lin P, Ross C, Li X, Smart NG, Beutler B. Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 19973-8. PMID 21045126 DOI: 10.1073/Pnas.1014051107  1
2010 Brandl K, Sun L, Neppl C, Siggs OM, Le Gall SM, Tomisato W, Li X, Du X, Maennel DN, Blobel CP, Beutler B. MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands Proceedings of the National Academy of Sciences of the United States of America. 107: 19967-19972. PMID 21041656 DOI: 10.1073/Pnas.1014669107  1
2010 Xia Y, Won S, Du X, Lin P, Ross C, La Vine D, Wiltshire S, Leiva G, Vidal SM, Whittle B, Goodnow CC, Koziol J, Moresco EMY, Beutler B. Bulk segregation mapping of mutations in closely related strains of mice Genetics. 186: 1139-1145. PMID 20923982 DOI: 10.1534/Genetics.110.121160  1
2010 Melo MB, Kasperkovitz P, Cerny A, Könen-Waisman S, Kurt-Jones EA, Lien E, Beutler B, Howard JC, Golenbock DT, Gazzinelli RT. UNC93B1 mediates host resistance to infection with toxoplasma gondii Plos Pathogens. 6: 83-84. PMID 20865117 DOI: 10.1371/Journal.Ppat.1001071  1
2010 Wingender G, Krebs P, Beutler B, Kronenberg M. Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency Journal of Immunology. 185: 2721-2729. PMID 20660713 DOI: 10.4049/Jimmunol.1001018  1
2010 Orinska Z, Föger N, Huber M, Marschall J, Mirghomizadeh F, Du X, Scheller M, Rosenstiel P, Goldmann T, Bollinger A, Beutler BA, Bulfone-Paus S. I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development. Blood. 116: 2665-75. PMID 20595514 DOI: 10.1182/Blood-2009-06-228460  1
2010 Eidenschenk C, Crozat K, Krebs P, Arens R, Popkin D, Arnold CN, Blasius AL, Benedict CA, Moresco EM, Xia Y, Beutler B. Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 9759-64. PMID 20457904 DOI: 10.1073/Pnas.1005186107  1
2010 Blasius AL, Beutler B. Intracellular Toll-like Receptors Immunity. 32: 305-315. PMID 20346772 DOI: 10.1016/J.Immuni.2010.03.012  1
2010 Berger M, Krebs P, Crozat K, Li X, Croker BA, Siggs OM, Popkin D, Du X, Lawson BR, Theofilopoulos AN, Xia Y, Khovananth K, Moresco EM, Satoh T, Takeuchi O, ... ... Beutler B, et al. An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence. Nature Immunology. 11: 335-43. PMID 20190759 DOI: 10.1038/Ni.1847  1
2010 Barnes MJ, Aksoylar H, Krebs P, Bourdeau T, Arnold CN, Xia Y, Khovananth K, Engel I, Sovath S, Lampe K, Laws E, Saunders A, Butcher GW, Kronenberg M, Steinbrecher K, ... ... Beutler B, et al. Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 3743-54. PMID 20190135 DOI: 10.4049/Jimmunol.0903164  1
2010 Theofilopoulos AN, Gonzalez-Quintial R, Lawson BR, Koh YT, Stern ME, Kono DH, Beutler B, Baccala R. Sensors of the innate immune system: their link to rheumatic diseases. Nature Reviews. Rheumatology. 6: 146-56. PMID 20142813 DOI: 10.1038/Nrrheum.2009.278  1
2010 Moresco EM, Beutler B. LGP2: positive about viral sensing. Proceedings of the National Academy of Sciences of the United States of America. 107: 1261-2. PMID 20133887 DOI: 10.1073/Pnas.0914011107  1
2010 Siggs OM, Berger M, Krebs P, Arnold CN, Eidenschenk C, Huber C, Pirie E, Smart NG, Khovananth K, Xia Y, McInerney G, Karlsson Hedestam GB, Nemazee D, Beutler B. A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha. Proceedings of the National Academy of Sciences of the United States of America. 107: 3046-51. PMID 20133626 DOI: 10.1073/Pnas.0915098107  1
2010 Liu H, Wang M, Xia CH, Du X, Flannery JG, Ridge KD, Beutler B, Gong X. Severe retinal degeneration caused by a novel rhodopsin mutation. Investigative Ophthalmology & Visual Science. 51: 1059-65. PMID 19741247 DOI: 10.1167/Iovs.09-3585  1
2010 Osborn O, Sanchez-Alavez M, Brownell SE, Ross B, Klaus J, Dubins J, Beutler B, Conti B, Bartfai T. Metabolic characterization of a mouse deficient in all known leptin receptor isoforms. Cellular and Molecular Neurobiology. 30: 23-33. PMID 19582570 DOI: 10.1007/S10571-009-9427-X  1
2009 Xiao N, Eidenschenk C, Krebs P, Brandl K, Blasius AL, Xia Y, Khovananth K, Smart NG, Beutler B. The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease Journal of Immunology. 183: 7975-7983. PMID 19923465 DOI: 10.4049/Jimmunol.0902718  1
2009 Flür K, Allam R, Zecher D, Kulkarni OP, Lichtnekert J, Schwarz M, Beutler B, Vielhauer V, Anders HJ. Viral RNA induces type i interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene-5: Implications for viral infection-associated glomerulonephritis American Journal of Pathology. 175: 2014-2022. PMID 19850889 DOI: 10.2353/Ajpath.2009.080585  1
2009 Jimenez-Dalmaroni MJ, Xiao N, Corper AL, Verdino P, Ainge GD, Larsen DS, Painter GF, Rudd PM, Dwek RA, Hoebe K, Beutler B, Wilson IA. Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2. Plos One. 4: e7411. PMID 19847289 DOI: 10.1371/Journal.Pone.0007411  1
2009 Truksa J, Gelbart T, Peng H, Beutler E, Beutler B, Lee P. Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6 British Journal of Haematology. 147: 571-581. PMID 19751239 DOI: 10.1111/J.1365-2141.2009.07873.X  1
2009 Slack E, Hapfelmeier S, Stecher B, Velykoredko Y, Stoel M, Lawson MA, Geuking MB, Beutler B, Tedder TF, Hardt WD, Bercik P, Verdu EF, McCoy KD, Macpherson AJ. Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science (New York, N.Y.). 325: 617-20. PMID 19644121 DOI: 10.1126/Science.1172747  1
2009 Baccala R, Gonzalez-Quintial R, Lawson BR, Stern ME, Kono DH, Beutler B, Theofilopoulos AN. Sensors of the innate immune system: their mode of action. Nature Reviews. Rheumatology. 5: 448-56. PMID 19597511 DOI: 10.1038/Nrrheum.2009.136  1
2009 Kono DH, Haraldsson MK, Lawson BR, Pollard KM, Koh YT, Du X, Arnold CN, Baccala R, Silverman GJ, Beutler BA, Theofilopoulos AN. Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus. Proceedings of the National Academy of Sciences of the United States of America. 106: 12061-6. PMID 19574451 DOI: 10.1073/Pnas.0905441106  1
2009 Fukui R, Saitoh SI, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing Journal of Experimental Medicine. 206: 1339-1350. PMID 19451267 DOI: 10.1084/Jem.20082316  1
2009 Krebs P, Barnes MJ, Lampe K, Whitley K, Bahjat KS, Beutler B, Janssen E, Hoebe K. NK cell-mediated killing of target cells triggers robust antigen-specific T cell-mediated and humoral responses Blood. 113: 6593-6602. PMID 19406986 DOI: 10.1182/Blood-2009-01-201467  1
2009 Pflugfelder SC, Stern ME, Beutler BA, Burns AR, Calonge M, Chodosh J, Dana MR, De Paiva CS, Fleiszig S, Hazlett LD, Huang AJ, Jones DB, Liu YJ, McDermott AM, Mircheff AK, et al. Immunoregulation on the ocular surface: 2nd cullen symposium Ocular Surface. 7: 67-77. PMID 19383275 DOI: 10.1016/S1542-0124(12)70297-5  1
2009 Barnes MJ, Krebs P, Harris N, Eidenschenk C, Gonzalez-Quintial R, Arnold CN, Crozat K, Sovath S, Moresco EM, Theofilopoulos AN, Beutler B, Hoebe K. Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery. Plos Biology. 7: e51. PMID 19260764 DOI: 10.1371/Journal.Pbio.1000051  1
2009 Brandl K, Rutschmann S, Li X, Du X, Xiao N, Schnabl B, Brenner DA, Beutler B. Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response Proceedings of the National Academy of Sciences of the United States of America. 106: 3300-3305. PMID 19202076 DOI: 10.1073/Pnas.0813036106  1
2009 Blasius AL, Brandl K, Crozat K, Xia Y, Khovananth K, Krebs P, Smart NG, Zampolli A, Ruggeri ZM, Beutler BA. Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function. Proceedings of the National Academy of Sciences of the United States of America. 106: 2706-11. PMID 19202056 DOI: 10.1073/Pnas.0813208106  1
2009 Lichtnekert J, Vielhauer V, Zecher D, Kulkarni OP, Clauss S, Segerer S, Hornung V, Mayadas TN, Beutler B, Akira S, Anders HJ. Trif is not required for immune complex glomerulonephritis: Dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif American Journal of Physiology - Renal Physiology. 296: F867-F874. PMID 19158348 DOI: 10.1152/Ajprenal.90213.2008  1
2009 Beutler B. Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases Immunological Reviews. 227: 248-263. PMID 19120489 DOI: 10.1111/J.1600-065X.2008.00733.X  1
2009 Beutler B. Obituary: Ernest Beutler (1928-2008) Haematologica. 94: 154-156. PMID 19118377 DOI: 10.3324/Haematol.13863  1
2009 Beutler BA. TLRs and innate immunity. Blood. 113: 1399-407. PMID 18757776 DOI: 10.1182/Blood-2008-07-019307  1
2008 Brzezinska AA, Johnson JL, Munafo DB, Crozat K, Beutler B, Kiosses WB, Ellis BA, Catz SD. The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules. Traffic (Copenhagen, Denmark). 9: 2151-64. PMID 18939952 DOI: 10.1111/J.1600-0854.2008.00838.X  1
2008 Croker BA, Lawson BR, Rutschmann S, Berger M, Eidenschenk C, Blasius AL, Moresco EM, Sovath S, Cengia L, Shultz LD, Theofilopoulos AN, Pettersson S, Beutler BA. Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger. Proceedings of the National Academy of Sciences of the United States of America. 105: 15028-33. PMID 18806225 DOI: 10.1073/Pnas.0806619105  1
2008 Beutler B, Moresco EM. The forward genetic dissection of afferent innate immunity. Current Topics in Microbiology and Immunology. 321: 3-26. PMID 18727485 DOI: 10.1007/978-3-540-75203-5_1  1
2008 Beutler B, Milsark IW, Cerami AC. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science, 1985, 229(4716):869-871. Classical article. Journal of Immunology (Baltimore, Md. : 1950). 181: 7-9. PMID 18566363  1
2008 Xia CH, Liu H, Cheung D, Wang M, Cheng C, Du X, Chang B, Beutler B, Gong X. A model for familial exudative vitreoretinopathy caused by LPR5 mutations. Human Molecular Genetics. 17: 1605-12. PMID 18263894 DOI: 10.1093/Hmg/Ddn047  1
2008 Croker BA, Lawson BR, Rutschmann S, Berger M, Eidenschenk C, Blasius AL, Moresco EMY, Sovath S, Cengia L, Shultz LD, Theofilopoulos AN, Pettersson S, Beutler BA. Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 39, (15028-15033) DOI:10.1073/pnas.0806619105) Proceedings of the National Academy of Sciences of the United States of America. 105: 19561. DOI: 10.1073/Pnas.0810917105  1
2008 Beutler B. Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunology - Preface Current Topics in Microbiology and Immunology. 321: v-viii. DOI: 10.1007/978-3-540-75203-5  1
2006 Xia CH, Liu H, Wang M, Cheung D, Park A, Yang Y, Du X, Chang B, Beutler B, Gong X. Characterization of mouse mutants with abnormal RPE cells. Advances in Experimental Medicine and Biology. 572: 95-100. PMID 17249561 DOI: 10.1007/0-387-32442-9_15  1
2006 Xia CH, Liu H, Cheung D, Cheng C, Wang E, Du X, Beutler B, Lo WK, Gong X. Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis. Development (Cambridge, England). 133: 2033-40. PMID 16611690 DOI: 10.1242/Dev.02361  1
2005 Beutler B, Cerami A. Cachectin--Tumour necrosis factor: a cytokine that mediates injury initiated by invasive parasites. Parasitology Today (Personal Ed.). 3: 345-6. PMID 15462882 DOI: 10.1016/0169-4758(87)90119-0  0.44
2000 Beutler B. Tlr4: central component of the sole mammalian LPS sensor. Current Opinion in Immunology. 12: 20-6. PMID 10679411 DOI: 10.1016/S0952-7915(99)00046-1  0.36
1999 Beutler BA. The role of tumor necrosis factor in health and disease. The Journal of Rheumatology. Supplement. 57: 16-21. PMID 10328138  1
1989 Cerami A, Beutler B. The role of cachectin/TNF in endotoxic shock and cachexia. Immunology Today. 9: 28-31. PMID 3076757 DOI: 10.1016/0167-5699(88)91353-9  0.48
1989 Beutler B, Cerami A. The history, properties, and biological effects of cachectin. Biochemistry. 27: 7575-82. PMID 3061461 DOI: 10.1021/Bi00420A001  0.48
1989 Mustafa MM, Ramilo O, Olsen KD, Franklin PS, Hansen EJ, Beutler B, McCracken GH. Tumor necrosis factor in mediating experimental Haemophilus influenzae type B meningitis Journal of Clinical Investigation. 84: 1253-1259. PMID 2794062 DOI: 10.1172/Jci114292  1
1989 Mustafa MM, Lebel MH, Ramilo O, Olsen KD, Reisch JS, Beutler B, McCracken GH. Correlation of interleukin-1β and cachectin concentrations in cerebrospinal fluid and outcome from bacterial meningitis The Journal of Pediatrics. 115: 208-213. PMID 2787856 DOI: 10.1016/S0022-3476(89)80067-8  1
1989 Beutler BA. Orchestration of septic shock by cytokines: the role of cachectin (tumor necrosis factor). Progress in Clinical and Biological Research. 286: 219-35. PMID 2648412  1
1989 Rettori V, Milenkovic L, Beutler BA, McCann SM. Hypothalamic action of cachectin to alter pituitary hormone release. Brain Research Bulletin. 23: 471-5. PMID 2611689 DOI: 10.1016/0361-9230(89)90192-5  1
1988 Beutler B, Thompson P, Keyes J, Hagerty K, Crawford D. Assay of a ribonuclease that preferentially hydrolyses mRNAs containing cytokine-derived UA-rich instability sequences Biochemical and Biophysical Research Communications. 152: 973-980. PMID 3288201 DOI: 10.1016/S0006-291X(88)80379-6  1
1988 Beutler B, Cerami A. Tumor necrosis, cachexia, shock, and inflammation: a common mediator. Annual Review of Biochemistry. 57: 505-18. PMID 3052281 DOI: 10.1146/Annurev.Bi.57.070188.002445  0.44
1988 Beutler B, Cerami A. The common mediator of shock, cachexia, and tumor necrosis. Advances in Immunology. 42: 213-31. PMID 2834923 DOI: 10.1016/S0065-2776(08)60846-9  0.48
1988 BEUTLER B, CERAMI A. Cachectin (Tumor Necrosis Factor): A Macrophage Hormone Governing Cellular Metabolism and Inflammatory Response Endocrine Reviews. 9: 57-66. DOI: 10.1210/Edrv-9-1-57  0.72
1988 Beutler B. Tumour necrosis factor and related cytokines (CIBA foundation symposium 131) Immunology Today. 9: 183. DOI: 10.1016/0167-5699(88)91296-0  0.4
1987 Beutler B, Cerami A. Cachectin: more than a tumor necrosis factor. The New England Journal of Medicine. 316: 379-85. PMID 3543677 DOI: 10.1056/Nejm198702123160705  0.52
1987 Cerami A, Beutler B. Cachectin: the dark side of tumor necrosis factor. Cold Spring Harbor Symposia On Quantitative Biology. 625-9. PMID 3472741 DOI: 10.1101/Sqb.1986.051.01.074  0.56
1987 Beutler B, Cerami A. Cachectin/tumor necrosis factor: an endogenous mediator of shock and inflammation. Immunologic Research. 5: 281-93. PMID 3036973 DOI: 10.1007/Bf02935501  0.4
1986 Dayer JM, Beutler B, Cerami A. Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. The Journal of Experimental Medicine. 162: 2163-8. PMID 2999289 DOI: 10.1084/Jem.162.6.2163  0.32
1985 Mahoney JR, Beutler BA, Le Trang N, Vine W, Ikeda Y, Kawakami M, Cerami A. Lipopolysaccharide-treated RAW 264.7 cells produce a mediator that inhibits lipoprotein lipase in 3T3-L1 cells. Journal of Immunology (Baltimore, Md. : 1950). 134: 1673-5. PMID 3968430  1
1985 Beutler B, Milsark IW, Cerami AC. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science (New York, N.Y.). 229: 869-71. PMID 3895437 DOI: 10.1126/Science.3895437  0.76
1985 Beutler B, Mahoney J, Le Trang N, Pekala P, Cerami A. Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells. The Journal of Experimental Medicine. 161: 984-95. PMID 3872925 DOI: 10.1084/Jem.161.5.984  0.4
1985 Beutler BA, Milsark IW, Cerami A. Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo. Journal of Immunology (Baltimore, Md. : 1950). 135: 3972-7. PMID 2999236  1
1985 Beutler BA, Cerami A. Recombinant interleukin 1 suppresses lipoprotein lipase activity in 3T3-L1 cells. Journal of Immunology (Baltimore, Md. : 1950). 135: 3969-71. PMID 2999235  1
1982 Beutler BA, Stefansson K, Arnason BG. A biochemically distinct sub-population of neurons in the human substantia gelatinosa. Study with G-6-PD histochemistry. Journal of the Neurological Sciences. 55: 175-83. PMID 6182274 DOI: 10.1016/0022-510X(82)90099-5  1
1981 Beutler BA, Noronha AB, Poon MM, Arnason BG. The absence of unique kainic acid-like molecules in urine, serum, and CSF from Huntington's disease patients. Journal of the Neurological Sciences. 51: 355-60. PMID 6115893 DOI: 10.1016/0022-510X(81)90113-1  1
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