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Johannes Graumann, Ph.D. - Publications

Affiliations: 
2000-2006 Biology Devision California Institute of Technology, Pasadena, CA 
 2011-2016 Biochemistry Weill Cornell Medical College in Qatar 
 2016-2021 Biomolecular Mass Spectrometry Max Planck Institute for Heart and Lung Research 
 2021- Institute of Translational Proteomics, Department of Medicine Philipps-Universität Marburg, Marburg, Hessen, Germany 
Area:
Proteomics, data analysis
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89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kudryashova TV, Dabral S, Nayakanti S, Ray A, Goncharov DA, Avolio T, Shen Y, Rode A, Pena A, Jiang L, Lin D, Baust J, Bachman TN, Graumann J, Ruppert C, et al. Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival. Circulation Research. CIRCRESAHA121319100. PMID 35124974 DOI: 10.1161/CIRCRESAHA.121.319100  0.223
2022 Gadd DA, Hillary RF, McCartney DL, Zaghlool SB, Stevenson AJ, Cheng Y, Fawns-Ritchie C, Nangle C, Campbell A, Flaig R, Harris SE, Walker RM, Shi L, Tucker-Drob EM, Gieger C, ... ... Graumann J, et al. Epigenetic scores for the circulating proteome as tools for disease prediction. Elife. 11. PMID 35023833 DOI: 10.7554/eLife.71802  0.338
2021 Sommerfeld L, Finkernagel F, Jansen JM, Wagner U, Nist A, Stiewe T, Müller-Brüsselbach S, Sokol AM, Graumann J, Reinartz S, Müller R. The multicellular signalling network of ovarian cancer metastases. Clinical and Translational Medicine. 11: e633. PMID 34841720 DOI: 10.1002/ctm2.633  0.247
2021 Jin YJ, Chennupati R, Li R, Liang G, Wang S, Iring A, Graumann J, Wettschureck N, Offermanns S. Protein kinase N2 mediates flow-induced eNOS activation and vascular tone regulation. The Journal of Clinical Investigation. PMID 34499618 DOI: 10.1172/JCI145734  0.285
2021 Sarvari P, Rasouli SJ, Allanki S, Stone OA, Sokol A, Graumann J, Stainier DYR. The E3 ubiquitin-protein ligase Rbx1 regulates cardiac wall morphogenesis in zebrafish. Developmental Biology. PMID 34363825 DOI: 10.1016/j.ydbio.2021.07.019  0.266
2021 Matías-García P, Wilson R, Guo Q, Zaghlool S, Eales J, Xu X, Charchar F, Dormer J, Maalmi H, Schlosser P, Elhadad M, Nano J, Sharma S, Peters A, Fornoni A, ... ... Graumann J, et al. Plasma Proteomics of Renal Function: A Trans-ethnic Meta-analysis and Mendelian Randomization Study. Journal of the American Society of Nephrology : Jasn. PMID 34135082 DOI: 10.1681/ASN.2020071070  0.275
2021 Elhadad MA, Wilson R, Zaghlool SB, Huth C, Gieger C, Grallert H, Graumann J, Rathmann W, Koenig W, Sinner MF, Hveem K, Suhre K, Thorand B, Jonasson C, Waldenberger M, et al. Metabolic syndrome and the plasma proteome: from association to causation. Cardiovascular Diabetology. 20: 111. PMID 34016094 DOI: 10.1186/s12933-021-01299-2  0.254
2021 Majeed Y, Halabi N, Madani AY, Engelke R, Bhagwat AM, Abdesselem H, Agha MV, Vakayil M, Courjaret R, Goswami N, Hamidane HB, Elrayess MA, Rafii A, Graumann J, Schmidt F, et al. SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways. Scientific Reports. 11: 8177. PMID 33854178 DOI: 10.1038/s41598-021-87759-x  0.346
2021 Tan DS, Chen Y, Gao Y, Bednarz A, Wei Y, Malik V, Ho DH, Weng M, Ho SY, Srivastava Y, Velychko S, Yang X, Fan L, Kim J, Graumann J, et al. Directed evolution of an enhanced POU reprogramming factor for cell fate engineering. Molecular Biology and Evolution. PMID 33720298 DOI: 10.1093/molbev/msab075  0.35
2021 Zaghlool SB, Sharma S, Molnar M, Matías-García PR, Elhadad MA, Waldenberger M, Peters A, Rathmann W, Graumann J, Gieger C, Grallert H, Suhre K. Revealing the role of the human blood plasma proteome in obesity using genetic drivers. Nature Communications. 12: 1279. PMID 33627659 DOI: 10.1038/s41467-021-21542-4  0.367
2021 Dobersch S, Rubio K, Singh I, Günther S, Graumann J, Cordero J, Castillo-Negrete R, Huynh MB, Mehta A, Braubach P, Cabrera-Fuentes H, Bernhagen J, Chao CM, Bellusci S, Günther A, et al. Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation. Nature Communications. 12: 1072. PMID 33594057 DOI: 10.1038/s41467-021-21227-y  0.291
2021 Verchère A, Cowton A, Jenni A, Rauch M, Häner R, Graumann J, Bütikofer P, Menon AK. Complexity of the eukaryotic dolichol-linked oligosaccharide scramblase suggested by activity correlation profiling mass spectrometry. Scientific Reports. 11: 1411. PMID 33446867 DOI: 10.1038/s41598-020-80956-0  0.334
2021 Dietze R, Hammoud MK, Gómez-Serrano M, Unger A, Bieringer T, Finkernagel F, Sokol AM, Nist A, Stiewe T, Reinartz S, Ponath V, Preußer C, von Strandmann EP, Müller-Brüsselbach S, Graumann J, et al. Phosphoproteomics identify arachidonic-acid-regulated signal transduction pathways modulating macrophage functions with implications for ovarian cancer. Theranostics. 11: 1377-1395. PMID 33391540 DOI: 10.7150/thno.52442  0.345
2020 Serricchio M, Hierro-Yap C, Schädeli D, Ben Hamidane H, Hemphill A, Graumann J, Zíková A, Bütikofer P. Depletion of cardiolipin induces major changes in energy metabolism in Trypanosoma brucei bloodstream forms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 33184899 DOI: 10.1096/fj.202001579RR  0.286
2020 Brumfield A, Chaudhary N, Molle D, Wen J, Graumann J, McGraw TE. Insulin promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10. Molecular Biology of the Cell. mbcE20060356. PMID 33175605 DOI: 10.1091/mbc.E20-06-0356  0.256
2020 Schutt C, Hallmann A, Hachim S, Klockner I, Valussi M, Atzberger A, Graumann J, Braun T, Boettger T. Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy. The Embo Journal. e105098. PMID 32960481 DOI: 10.15252/Embj.2020105098  0.41
2020 Elhadad MA, Jonasson C, Huth C, Wilson R, Gieger C, Matias P, Grallert H, Graumann J, Gailus-Durner V, Rathmann W, von Toerne C, Hauck SM, Koenig W, Sinner MF, Oprea TI, et al. Deciphering the Plasma Proteome of Type 2 Diabetes. Diabetes. PMID 32928870 DOI: 10.2337/Db20-0296  0.378
2020 Bhagwat AM, Graumann J, Wiegandt R, Bentsen M, Welker J, Kuenne C, Preussner J, Braun T, Looso M. multicrispr: gRNA design for prime editing and parallel targeting of thousands of targets. Life Science Alliance. 3. PMID 32907859 DOI: 10.26508/lsa.202000757  0.259
2020 Fukuda R, Marín-Juez R, El-Sammak H, Beisaw A, Ramadass R, Kuenne C, Guenther S, Konzer A, Bhagwat AM, Graumann J, Stainier DY. Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish. Embo Reports. e49752. PMID 32648304 DOI: 10.15252/Embr.201949752  0.384
2020 Wu CC, Jeratsch S, Graumann J, Stainier D. Modulation of Mammalian Cardiomyocyte Cytokinesis by the Extracellular Matrix. Circulation Research. PMID 32564729 DOI: 10.1161/Circresaha.119.316303  0.393
2020 Kahal H, Halama A, Aburima A, Bhagwat AM, Butler AE, Graumann J, Suhre K, Sathyapalan T, Atkin SL. Author Correction: Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects. Scientific Reports. 10: 10233. PMID 32561766 DOI: 10.1038/S41598-020-66189-1  0.317
2020 Steitz AM, Steffes A, Finkernagel F, Unger A, Sommerfeld L, Jansen JM, Wagner U, Graumann J, Müller R, Reinartz S. Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C. Cell Death & Disease. 11: 249. PMID 32312959 DOI: 10.1038/S41419-020-2438-8  0.434
2020 Li M, Nishio SY, Naruse C, Riddell M, Sapski S, Katsuno T, Hikita T, Mizapourshafiyi F, Smith FM, Cooper LT, Lee MG, Asano M, Boettger T, Krueger M, Wietelmann A, ... Graumann J, et al. Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome. Nature Communications. 11: 1343. PMID 32165640 DOI: 10.1038/S41467-020-15198-9  0.353
2020 Zaghlool SB, Kühnel B, Elhadad MA, Kader S, Halama A, Thareja G, Engelke R, Sarwath H, Al-Dous EK, Mohamoud YA, Meitinger T, Wilson R, Strauch K, Peters A, Mook-Kanamori DO, ... Graumann J, et al. Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits. Nature Communications. 11: 15. PMID 31900413 DOI: 10.1038/S41467-019-13831-W  0.432
2020 Elhadad MA, Jonasson C, Huth C, Wilson R, Thorand B, Grallert H, Graumann J, Rathmann W, Koenig W, Sinner MF, Gieger C, Suhre K, Hveem K, Peters A, Waldenberger M. Abstract 21: Deciphering the Plasma Proteome of Type 2 Diabetes Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.21  0.458
2019 Deutschmeyer V, Breuer J, Walesch SK, Sokol AM, Graumann J, Bartkuhn M, Boettger T, Rossbach O, Richter AM. Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function. Clinical Epigenetics. 11: 182. PMID 31801617 DOI: 10.1186/S13148-019-0774-2  0.348
2019 Chauhan N, Sere YY, Sokol AM, Graumann J, Menon AK. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol binding proteins in Saccharomyces cerevisiae. Yeast (Chichester, England). PMID 31758572 DOI: 10.1002/Yea.3448  0.481
2019 Graumann J, Finkernagel F, Reinartz S, Stief T, Brödje D, Renz H, Jansen JM, Wagner U, Worzfeld T, Pogge von Strandmann E, Müller R. Multi-platform Affinity Proteomics Identify Proteins Linked to Metastasis and Immune Suppression in Ovarian Cancer Plasma. Frontiers in Oncology. 9: 1150. PMID 31737572 DOI: 10.3389/Fonc.2019.01150  0.443
2019 Finkernagel F, Reinartz S, Schuldner M, Malz A, Jansen JM, Wagner U, Worzfeld T, Graumann J, von Strandmann EP, Müller R. Dual-platform affinity proteomics identifies links between the recurrence of ovarian carcinoma and proteins released into the tumor microenvironment. Theranostics. 9: 6601-6617. PMID 31588238 DOI: 10.7150/Thno.37549  0.461
2019 Schädeli D, Serricchio M, Ben Hamidane H, Loffreda A, Hemphill A, Beneke T, Gluenz E, Graumann J, Bütikofer P. Cardiolipin depletion-induced changes in the proteome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901184RR. PMID 31536395 DOI: 10.1096/Fj.201901184Rr  0.453
2019 Fukuda R, Gunawan F, Ramadass R, Beisaw A, Konzer A, Mullapudi ST, Gentile A, Maischein HM, Graumann J, Stainier DYR. Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis. Developmental Cell. PMID 31495694 DOI: 10.1016/J.Devcel.2019.08.006  0.388
2019 Kesireddy VS, Chillappagari S, Ahuja S, Knudsen L, Henneke I, Graumann J, Meiners S, Ochs M, Ruppert C, Korfei M, Seeger W, Mahavadi P. Susceptibility of microtubuleassociated protein 1 light chain 3β (MAP1LC3B/ LC3B) knockout mice to lung injury and fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900854R. PMID 31431059 DOI: 10.1096/Fj.201900854R  0.382
2019 Billing AM, Dib SS, Bhagwat AM, da Silva IT, Drummond RD, Hayat S, Al-Mismar R, Ben Hamidane H, Goswami N, Engholm-Keller K, Larsen MR, Suhre K, Rafii A, Graumann J. A Systems-Level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells. Molecular & Cellular Proteomics : McP. PMID 31332097 DOI: 10.1074/Mcp.Ra119.001356  0.745
2019 Suhre K, Trbojević-Akmačić I, Ugrina I, Mook-Kanamori DO, Spector T, Graumann J, Lauc G, Falchi M. Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome. Metabolites. 9. PMID 31247951 DOI: 10.3390/Metabo9070122  0.43
2019 Iring A, Jin YJ, Albarrán-Juárez J, Siragusa M, Wang S, Dancs PT, Nakayama A, Tonack S, Chen M, Künne C, Sokol AM, Günther S, Martínez A, Fleming I, Wettschureck N, ... Graumann J, et al. Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure. The Journal of Clinical Investigation. 130. PMID 31205027 DOI: 10.1172/Jci123825  0.354
2019 Adams V, Bowen TS, Werner S, Barthel P, Amberger C, Konzer A, Graumann J, Sehr P, Lewis J, Provaznik J, Benes V, Büttner P, Gasch A, Mangner N, Witt CC, et al. Small-molecule-mediated chemical knock-down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure. Journal of Cachexia, Sarcopenia and Muscle. PMID 31140761 DOI: 10.1002/Jcsm.12448  0.324
2019 Kiweler M, Looso M, Graumann J. MARMoSET - Extracting Publication-Ready Mass Spectrometry Metadata from RAW Files. Molecular & Cellular Proteomics : McP. PMID 31097673 DOI: 10.1074/Mcp.Tir119.001505  0.354
2019 Yu F, Hubrack SZ, Chakraborty S, Sun L, Alcantara-Adap E, Kulkarni R, Billing AM, Graumann J, Taylor CW, Machaca K. Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca influx in mitosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31064875 DOI: 10.1073/Pnas.1821399116  0.72
2019 Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A. Correction: Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish. Plos Genetics. 15: e1007972. PMID 30703099 DOI: 10.1371/Journal.Pgen.1007972  0.312
2019 Elsemüller AK, Tomalla V, Gärtner U, Troidl K, Jeratsch S, Graumann J, Baal N, Hackstein H, Lasch M, Deindl E, Preissner KT, Fischer S. Characterization of mast cell-derived rRNA-containing microvesicles and their inflammatory impact on endothelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201801853RR. PMID 30702929 DOI: 10.1096/Fj.201801853Rr  0.401
2018 Halama A, Kahal H, Bhagwat AM, Zierer J, Sathyapalan T, Graumann J, Suhre K, Atkin SL. Metabolic and proteomic signatures of hypoglycaemia in type 2 diabetes. Diabetes, Obesity & Metabolism. PMID 30525282 DOI: 10.1111/Dom.13602  0.334
2018 Mullapudi ST, Helker CS, Boezio GL, Maischein HM, Sokol AM, Guenther S, Matsuda H, Kubicek S, Graumann J, Yang YHC, Stainier DY. Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists. Elife. 7. PMID 30520733 DOI: 10.7554/Elife.42209  0.342
2018 Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A. Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish. Plos Genetics. 14: e1007743. PMID 30457989 DOI: 10.1371/Journal.Pgen.1007743  0.387
2018 Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, et al. Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease. Nature Communications. 9: 4600. PMID 30389913 DOI: 10.1038/S41467-018-06833-7  0.372
2018 Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, et al. Cell-type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment. Molecular Oncology. PMID 30353652 DOI: 10.1002/1878-0261.12396  0.421
2018 Hodeify R, Nandakumar M, Own M, Courjaret RJ, Graumann J, Hubrack SZ, Machaca K. The CCT chaperonin is a novel regulator of Ca signaling through modulation of Orai1 trafficking. Science Advances. 4: eaau1935. PMID 30263962 DOI: 10.1126/Sciadv.Aau1935  0.402
2018 Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, ... Graumann J, et al. Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nature Communications. 9: 3853. PMID 30228274 DOI: 10.1038/S41467-018-06231-Z  0.632
2018 Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, ... Graumann J, et al. Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nature Communications. 9: 3268. PMID 30111768 DOI: 10.1038/S41467-018-05512-X  0.667
2018 Singh I, Contreras A, Cordero J, Rubio K, Dobersch S, Günther S, Jeratsch S, Mehta A, Krüger M, Graumann J, Seeger W, Dobreva G, Braun T, Barreto G. MiCEE is a ncRNA-protein complex that mediates epigenetic silencing and nucleolar organization. Nature Genetics. PMID 29867223 DOI: 10.1038/S41588-018-0139-3  0.418
2018 Nader N, Dib M, Courjaret R, Hodeify R, Machaca R, Graumann J, Machaca K. VLDL receptor regulates membrane progesterone receptor trafficking and non-genomic signaling. Journal of Cell Science. PMID 29685893 DOI: 10.1242/Jcs.212522  0.376
2018 Choi S, Bhagwat AM, Al Mismar R, Goswami N, Ben Hamidane H, Sun L, Graumann J. Proteomic profiling of human cancer pseudopodia for the identification of anti-metastatic drug candidates. Scientific Reports. 8: 5858. PMID 29643415 DOI: 10.1038/S41598-018-24256-8  0.671
2018 Zaghlool SB, Mook-Kanamori DO, Kader S, Stephan N, Halama A, Engelke R, Sarwath H, Al-Dous EK, Mohamoud YA, Roemisch-Margl W, Adamski J, Kastenmüller G, Friedrich N, Visconti A, Tsai PC, ... ... Graumann J, et al. Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation. Human Molecular Genetics. PMID 29325019 DOI: 10.1093/Hmg/Ddy006  0.413
2018 Mullapudi ST, Helker CS, Boezio GL, Maischein H, Sokol AM, Guenther S, Matsuda H, Kubicek S, Graumann J, Yang YHC, Stainier DY. Author response: Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists Elife. DOI: 10.7554/Elife.42209.021  0.333
2018 Graumann J, Cotton R. multipanelfigure: Simple Assembly of Multiple Plots and Images into a Compound Figure Journal of Statistical Software. 84. DOI: 10.18637/Jss.V084.C03  0.318
2018 Elhadad MA, Wilson R, Zaghlool S, Huth C, Kriebel J, Grallert H, Rathmann W, Graumann J, Suhre K, Peters A, Gieger C, Waldenberger M. P4769Using the plasma proteome to decipher metabolic syndrome pathophysiology and discover a diagnostic biomarker panel European Heart Journal. 39. DOI: 10.1093/Eurheartj/Ehy563.P4769  0.362
2017 Worzfeld T, Finkernagel F, Reinartz S, Konzer A, Adhikary T, Nist A, Stiewe T, Wagner U, Looso M, Graumann J, Müller R. Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment. Molecular & Cellular Proteomics : McP. PMID 29141914 DOI: 10.1074/Mcp.Ra117.000400  0.41
2017 Guo M, Zhang T, Dong X, Xiang JZ, Lei M, Evans T, Graumann J, Chen S. Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E. Cell Reports. 19: 1512-1521. PMID 28538172 DOI: 10.1016/J.Celrep.2017.04.070  0.423
2017 Cotton RJ, Ploier B, Goren MA, Menon AK, Graumann J. flippant-An R package for the automated analysis of fluorescence-based scramblase assays. Bmc Bioinformatics. 18: 146. PMID 28253836 DOI: 10.1186/S12859-017-1542-Y  0.382
2017 Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MA, Mook-Kanamori DO, ... ... Graumann J, et al. Connecting genetic risk to disease end points through the human blood plasma proteome. Nature Communications. 8: 14357. PMID 28240269 DOI: 10.1038/Ncomms14357  0.425
2016 Askenazi M, Ben Hamidane H, Graumann J. The arc of Mass Spectrometry Exchange Formats is long, but it bends toward HDF5. Mass Spectrometry Reviews. PMID 27741559 DOI: 10.1002/Mas.21522  0.345
2016 Ploier B, Caro LN, Morizumi T, Pandey K, Pearring JN, Goren MA, Finnemann SC, Graumann J, Arshavsky VY, Dittman JS, Ernst OP, Menon AK. Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants. Nature Communications. 7: 12832. PMID 27694816 DOI: 10.1038/Ncomms12832  0.366
2016 Billing AM, Hamidane HB, Bhagwat AM, Cotton RJ, Dib SS, Kumar P, Hayat S, Goswami N, Suhre K, Rafii A, Graumann J. Complementarity of SOMAscan to LC-MS/MS and RNA-seq for quantitative profiling of human embryonic and mesenchymal stem cells. Journal of Proteomics. PMID 27613379 DOI: 10.1016/J.Jprot.2016.08.023  0.757
2016 Zeng H, Guo M, Zhou T, Tan L, Chong CN, Zhang T, Dong X, Xiang JZ, Yu AS, Yue L, Qi Q, Evans T, Graumann J, Chen S. An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery. Cell Stem Cell. PMID 27524441 DOI: 10.1016/J.Stem.2016.07.002  0.411
2016 Graham B, Marcais A, Dharmalingam G, Carroll T, Kanellopoulou C, Graumann J, Nesterova TB, Bermange A, Brazauskas P, Xella B, Kriaucionis S, Higgs DR, Brockdorff N, Mann M, Fisher AG, et al. MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells. Stem Cell Reports. 6: 635-642. PMID 27150236 DOI: 10.1016/J.Stemcr.2016.03.005  0.489
2016 Cotton RJ, Graumann J. readat: An R package for reading and working with SomaLogic ADAT files. Bmc Bioinformatics. 17: 201. PMID 27146037 DOI: 10.1186/S12859-016-1007-8  0.379
2016 Billing AM, Ben Hamidane H, Dib SS, Cotton RJ, Bhagwat AM, Kumar P, Hayat S, Yousri NA, Goswami N, Suhre K, Rafii A, Graumann J. Comprehensive transcriptomic and proteomic characterization of human mesenchymal stem cells reveals source specific cellular markers. Scientific Reports. 6: 21507. PMID 26857143 DOI: 10.1038/Srep21507  0.74
2016 Abdesselem H, Madani A, Hani A, Al-Noubi M, Goswami N, Ben Hamidane H, Billing AM, Pasquier J, Bonkowski MS, Halabi N, Dalloul R, Sheriff MZ, Mesaeli N, ElRayess M, Sinclair DA, ... Graumann J, et al. SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition. The Journal of Biological Chemistry. 291: 2119-35. PMID 26655722 DOI: 10.1074/Jbc.M115.675645  0.74
2016 Abdesselem H, Madani A, Hani A, Al-Noubi M, Goswami N, Ben Hamidane H, Billing AM, Pasquier J, Bonkowski MS, Halabi N, Dalloul R, Sheriff MZ, Mesaeli N, ElRayess M, Sinclair DA, ... Graumann J, et al. SIRT1 limits adipocyte hyperplasia through c-Myc inhibition Journal of Biological Chemistry. 291: 2119-2135. DOI: 10.1074/jbc.M115.675645  0.229
2015 Billing AM, Ben Hamidane H, Graumann J. Quantitative proteomic approaches in mouse: stable isotope incorporation by metabolic (SILAC) or chemical labeling (reductive dimethylation) combined with high-resolution mass spectrometry. Current Protocols in Mouse Biology. 5: 1-20. PMID 25727197 DOI: 10.1002/9780470942390.Mo140156  0.747
2015 Graham B, Marcais A, Dharmalingam G, Carroll T, Kanellopoulou C, Graumann J, Nesterova TB, Bermange A, Brazauskas P, Xella B, Kriaucionis S, Higgs DR, Brockdorff N, Mann M, Fisher AG, et al. MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells Stem Cell Reports. DOI: 10.1016/j.stemcr.2016.03.005  0.429
2014 Marcais A, Blevins R, Graumann J, Feytout A, Dharmalingam G, Carroll T, Amado IF, Bruno L, Lee K, Walzer T, Mann M, Freitas AA, Boothby M, Fisher AG, Merkenschlager M. microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells. The Journal of Experimental Medicine. 211: 2281-95. PMID 25311506 DOI: 10.1084/Jem.20132059  0.479
2014 Blanc V, Park E, Schaefer S, Miller M, Lin Y, Kennedy S, Billing AM, Ben Hamidane H, Graumann J, Mortazavi A, Nadeau JH, Davidson NO. Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver. Genome Biology. 15: R79. PMID 24946870 DOI: 10.1186/Gb-2014-15-6-R79  0.718
2013 Liberski AR, Al-Noubi MN, Rahman ZH, Halabi NM, Dib SS, Al-Mismar R, Billing AM, Krishnankutty R, Ahmad FS, Raynaud CM, Rafii A, Engholm-Keller K, Graumann J. Adaptation of a commonly used, chemically defined medium for human embryonic stem cells to stable isotope labeling with amino acids in cell culture Journal of Proteome Research. 12: 3233-3245. PMID 23734825 DOI: 10.1021/Pr400099J  0.736
2013 Stoehr G, Schaab C, Graumann J, Mann M. A SILAC-based approach identifies substrates of caspase-dependent cleavage upon TRAIL-induced apoptosis. Molecular & Cellular Proteomics : McP. 12: 1436-50. PMID 23319142 DOI: 10.1074/Mcp.M112.024679  0.517
2012 O'Loghlen A, Muñoz-Cabello AM, Gaspar-Maia A, Wu HA, Banito A, Kunowska N, Racek T, Pemberton HN, Beolchi P, Lavial F, Masui O, Vermeulen M, Carroll T, Graumann J, Heard E, et al. MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell. 10: 33-46. PMID 22226354 DOI: 10.1016/J.Stem.2011.12.004  0.412
2012 Graumann J, Scheltema RA, Zhang Y, Cox J, Mann M. A framework for intelligent data acquisition and real-time database searching for shotgun proteomics. Molecular & Cellular Proteomics : McP. 11: M111.013185. PMID 22171319 DOI: 10.1074/Mcp.M111.013185  0.471
2010 Singhal N, Graumann J, Wu G, Araúzo-Bravo MJ, Han DW, Greber B, Gentile L, Mann M, Schöler HR. Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming. Cell. 141: 943-55. PMID 20550931 DOI: 10.1016/J.Cell.2010.04.037  0.52
2008 Alexandru G, Graumann J, Smith GT, Kolawa NJ, Fang R, Deshaies RJ. UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. Cell. 134: 804-16. PMID 18775313 DOI: 10.1016/J.Cell.2008.06.048  0.731
2008 Graumann J, Hubner NC, Kim JB, Ko K, Moser M, Kumar C, Cox J, Schöler H, Mann M. Stable isotope labeling by amino acids in cell culture (SILAC) and proteome quantitation of mouse embryonic stem cells to a depth of 5,111 proteins. Molecular & Cellular Proteomics : McP. 7: 672-83. PMID 18045802 DOI: 10.1074/Mcp.M700460-Mcp200  0.566
2007 Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ. Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway. Molecular & Cellular Proteomics : McP. 6: 1885-95. PMID 17644757 DOI: 10.1074/Mcp.M700264-Mcp200  0.633
2007 Dieterich DC, Lee JJ, Link AJ, Graumann J, Tirrell DA, Schuman EM. Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging. Nature Protocols. 2: 532-40. PMID 17406607 DOI: 10.1038/Nprot.2007.52  0.597
2006 Dieterich DC, Link AJ, Graumann J, Tirrell DA, Schuman EM. Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proceedings of the National Academy of Sciences of the United States of America. 103: 9482-7. PMID 16769897 DOI: 10.1073/Pnas.0601637103  0.612
2005 Griffin EE, Graumann J, Chan DC. The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria. The Journal of Cell Biology. 170: 237-48. PMID 16009724 DOI: 10.1083/Jcb.200503148  0.383
2005 Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ. Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets. Molecular & Cellular Proteomics : McP. 4: 741-51. PMID 15699485 DOI: 10.1074/Mcp.M400220-Mcp200  0.651
2004 McDonald WH, Tabb DL, Sadygov RG, MacCoss MJ, Venable J, Graumann J, Johnson JR, Cociorva D, Yates JR. MS1, MS2, and SQT-three unified, compact, and easily parsed file formats for the storage of shotgun proteomic spectra and identifications. Rapid Communications in Mass Spectrometry : Rcm. 18: 2162-8. PMID 15317041 DOI: 10.1002/Rcm.1603  0.368
2004 Verma R, Oania R, Graumann J, Deshaies RJ. Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system. Cell. 118: 99-110. PMID 15242647 DOI: 10.1016/J.Cell.2004.06.014  0.603
2004 Graumann J, Dunipace LA, Seol JH, McDonald WH, Yates JR, Wold BJ, Deshaies RJ. Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast. Molecular & Cellular Proteomics : McP. 3: 226-37. PMID 14660704 DOI: 10.1074/Mcp.M300099-Mcp200  0.649
2001 Graumann J, Lilie H, Tang X, Tucker KA, Hoffmann JH, Vijayalakshmi J, Saper M, Bardwell JC, Jakob U. Activation of the redox-regulated molecular chaperone Hsp33--a two-step mechanism. Structure (London, England : 1993). 9: 377-87. PMID 11377198 DOI: 10.1016/S0969-2126(01)00599-8  0.354
2001 Vijayalakshmi J, Mukhergee MK, Graumann J, Jakob U, Saper MA. The 2.2 Å crystal structure of Hsp33: A heat shock protein with redox-regulated chaperone activity Structure. 9: 367-375. PMID 11377197 DOI: 10.1016/S0969-2126(01)00597-4  0.391
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