Tianyan Gao - Publications

Affiliations: 
2000-2006 University of Kentucky, Lexington, KY 

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Li J, Song J, Zaytseva YY, Liu Y, Rychahou P, Jiang K, Starr ME, Kim JT, Harris JW, Yiannikouris FB, Katz WS, Nilsson PM, Orho-Melander M, Chen J, Zhu H, ... ... Gao T, et al. An obligatory role for neurotensin in high-fat-diet-induced obesity. Nature. 533: 411-5. PMID 27193687 DOI: 10.1038/nature17662  0.4
2016 Smith AJ, Wen YA, Stevens PD, Liu J, Wang C, Gao T. PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells. Oncotarget. PMID 26760962 DOI: 10.18632/oncotarget.6848  0.4
2015 Goretsky T, Bradford EM, Ryu H, Tahir M, Moyer MP, Gao T, Li L, Barrett TA. A Cytosolic Multiprotein Complex containing p85α is required for β-catenin Activation in Colitis and Colitis-associated Cancer. The Journal of Biological Chemistry. PMID 26565021 DOI: 10.1074/jbc.M115.669416  0.4
2015 Zaytseva YY, Harris JW, Mitov MI, Kim JT, Butterfield DA, Lee EY, Weiss HL, Gao T, Evers BM. Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration. Oncotarget. PMID 25970773  0.4
2015 Jackson TC, Bayir H, Ikonomovic MD, Janesko-Feldman K, Mi Z, Gao T, Jackson EK, Kochanek PM. Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies. Scientific Reports. 5: 9377. PMID 25827478 DOI: 10.1038/srep09377  0.4
2015 Harris JW, Gao T, Mark Evers B. The role of PI3K signaling pathway in intestinal tumorigenesis Intestinal Tumorigenesis: Mechanisms of Development & Progression. 101-135. DOI: 10.1007/978-3-319-19986-3_4  0.4
2014 Reyes G, Niederst M, Cohen-Katsenelson K, Stender JD, Kunkel MT, Chen M, Brognard J, Sierecki E, Gao T, Nowak DG, Trotman LC, Glass CK, Newton AC. Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output. Proceedings of the National Academy of Sciences of the United States of America. 111: E3957-65. PMID 25201979 DOI: 10.1073/pnas.1404221111  0.4
2014 Zaytseva YY, Elliott VA, Rychahou P, Mustain WC, Kim JT, Valentino J, Gao T, O'Connor KL, Neltner JM, Lee EY, Weiss HL, Evers BM. Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer. Carcinogenesis. 35: 1341-51. PMID 24510238 DOI: 10.1093/carcin/bgu042  0.4
2014 Li X, Gao T. MTORC2 phosphorylates protein kinase Cζ to regulate its stability and activity Embo Reports. 15: 191-198. PMID 24375676 DOI: 10.1002/embr.201338119  0.4
2013 Wen YA, Stevens PD, Gasser ML, Andrei R, Gao T. Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells. Molecular and Cellular Biology. 33: 4594-605. PMID 24061475 DOI: 10.1128/MCB.00695-13  0.4
2012 Li J, Song J, Cassidy MG, Rychahou P, Starr ME, Liu J, Li X, Epperly G, Weiss HL, Townsend CM, Gao T, Evers BM. PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport. Molecular Endocrinology (Baltimore, Md.). 26: 1380-93. PMID 22700584 DOI: 10.1210/me.2012-1024  0.4
2012 Gulhati P, Zaytseva YY, Valentino JD, Stevens PD, Kim JT, Sasazuki T, Shirasawa S, Lee EY, Weiss HL, Dong J, Gao T, Evers BM. Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA. Carcinogenesis. 33: 1782-90. PMID 22696593 DOI: 10.1093/carcin/bgs203  0.4
2011 Liu J, Stevens PD, Li X, Schmidt MD, Gao T. PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth. Molecular and Cellular Biology. 31: 4917-27. PMID 21986499 DOI: 10.1128/MCB.05799-11  0.4
2011 Ojeda L, Gao J, Hooten KG, Wang E, Thonhoff JR, Dunn TJ, Gao T, Wu P. Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF. Plos One. 6: e23414. PMID 21887250 DOI: 10.1371/journal.pone.0023414  0.4
2011 Li X, Yang H, Liu J, Schmidt MD, Gao T. Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt. Embo Reports. 12: 818-24. PMID 21701506 DOI: 10.1038/embor.2011.106  0.4
2011 Li J, Liu J, Song J, Wang X, Weiss HL, Townsend CM, Gao T, Evers BM. mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON. American Journal of Physiology. Cell Physiology. 301: C213-26. PMID 21508335 DOI: 10.1152/ajpcell.00067.2011  0.4
2011 Patterson SJ, Han JM, Garcia R, Assi K, Gao T, O'Neill A, Newton AC, Levings MK. Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 5533-7. PMID 21498666 DOI: 10.4049/jimmunol.1002126  0.4
2011 Gulhati P, Bowen KA, Liu J, Stevens PD, Rychahou PG, Chen M, Lee EY, Weiss HL, O'Connor KL, Gao T, Evers BM. mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways. Cancer Research. 71: 3246-56. PMID 21430067 DOI: 10.1158/0008-5472.CAN-10-4058  0.4
2010 Miyamoto S, Purcell NH, Smith JM, Gao T, Whittaker R, Huang K, Castillo R, Glembotski CC, Sussman MA, Newton AC, Brown JH. PHLPP-1 negatively regulates Akt activity and survival in the heart. Circulation Research. 107: 476-84. PMID 20576936 DOI: 10.1161/CIRCRESAHA.109.215020  0.4
2010 Masubuchi S, Gao T, O'Neill A, Eckel-Mahan K, Newton AC, Sassone-Corsi P. Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 107: 1642-7. PMID 20080691 DOI: 10.1073/pnas.0910292107  0.4
2009 Gulhati P, Cai Q, Li J, Liu J, Rychahou PG, Qiu S, Lee EY, Silva SR, Bowen KA, Gao T, Evers BM. Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 7207-16. PMID 19934294 DOI: 10.1158/1078-0432.CCR-09-1249  0.4
2009 Liu J, Weiss HL, Rychahou P, Jackson LN, Evers BM, Gao T. Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis. Oncogene. 28: 994-1004. PMID 19079341 DOI: 10.1038/onc.2008.450  0.4
2008 Gao T, Brognard J, Newton AC. The phosphatase PHLPP controls the cellular levels of protein kinase C. The Journal of Biological Chemistry. 283: 6300-11. PMID 18162466 DOI: 10.1074/jbc.M707319200  0.4
2007 Chen D, Gould C, Garza R, Gao T, Hampton RY, Newton AC. Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase. The Journal of Biological Chemistry. 282: 33776-87. PMID 17893151 DOI: 10.1074/jbc.M703320200  0.4
2007 Brognard J, Sierecki E, Gao T, Newton AC. PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms. Molecular Cell. 25: 917-31. PMID 17386267 DOI: 10.1016/j.molcel.2007.02.017  0.4
2006 Gao T, Newton AC. Invariant Leu preceding turn motif phosphorylation site controls the interaction of protein kinase C with Hsp70 Journal of Biological Chemistry. 281: 32461-32468. PMID 16954220 DOI: 10.1074/jbc.M604076200  0.4
2005 Gao T, Furnari F, Newton AC. PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Molecular Cell. 18: 13-24. PMID 15808505 DOI: 10.1016/j.molcel.2005.03.008  0.4
2002 Gao T, Newton AC. The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C Journal of Biological Chemistry. 277: 31585-31592. PMID 12080070 DOI: 10.1074/jbc.M204335200  0.4
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