Mark Alan Sussman - Publications

Affiliations: 
1995-2003 Molecular Cardiovascular Biology University of Cincinnati College of Medicine, Cincinnati, OH, United States 
 2003- Biology California State University, Los Angeles, CA, United States 
Area:
myocardial research
Website:
http://heart.sdsu.edu/lab/meet-dr-sussman/

197 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cho J, Kim S, Lee H, Rah W, Cho HC, Kim NK, Bae S, Shin DH, Lee MG, Park IH, Tanaka Y, Shin E, Yi H, Han JW, Hwang PTJ, ... ... Sussman MA, et al. Regeneration of infarcted mouse hearts by cardiovascular tissue formed via the direct reprogramming of mouse fibroblasts. Nature Biomedical Engineering. 5: 880-896. PMID 34426676 DOI: 10.1038/s41551-021-00783-0  0.332
2020 Ebeid DE, Firouzi F, Esquer CY, Navarrete JM, Wang BJ, Gude NA, Sussman MA. PIM1 Promotes Survival of Cardiomyocytes by Upregulating c-Kit Protein Expression. Cells. 9. PMID 32878131 DOI: 10.3390/Cells9092001  0.399
2020 Monsanto MM, Wang BJ, Ehrenberg ZR, Echeagaray O, White KS, Alvarez R, Fisher K, Sengphanith S, Muliono A, Gude NA, Sussman MA. Enhancing myocardial repair with CardioClusters. Nature Communications. 11: 3955. PMID 32769998 DOI: 10.1038/S41467-020-17742-Z  0.472
2020 Monsanto MM, Firouzi F, Sussman MA. Hiding in plain sight: an encapsulated approach to cardiac cell therapy. Cardiovascular Research. PMID 32750104 DOI: 10.1093/Cvr/Cvaa242  0.385
2020 Sussman MA. Atrial myxoma: the cardiac chameleon. European Heart Journal. PMID 32330936 DOI: 10.1093/Eurheartj/Ehaa208  0.372
2020 Ebeid DE, Khalafalla FG, Broughton KM, Monsanto MM, Esquer CY, Sacchi V, Hariharan N, Korski KI, Moshref M, Emathinger J, Cottage CT, Quijada PJ, Nguyen JH, Alvarez R, Völkers M, ... ... Sussman MA, et al. Pim1 Maintains Telomere Length in Mouse Cardiomyocytes by Inhibiting TGFβ Signaling. Cardiovascular Research. PMID 32176281 DOI: 10.1093/Cvr/Cvaa066  0.331
2020 Firouzi F, Sinha Choudhury S, Broughton K, Salazar A, Bailey B, Sussman MA. Human CardioChimeras: Creation of a Novel "Next-Generation" Cardiac Cell. Journal of the American Heart Association. 9: e013452. PMID 31902324 DOI: 10.1161/Jaha.119.013452  0.413
2020 Kayani W, Wang B, Korski K, Stavropoulos A, Sussman M, Khalafalla F. P2X5 purinergic receptor: A novel regulator of human cardiac progenitor cell proliferation and survival Journal of Molecular and Cellular Cardiology. 140: 13. DOI: 10.1016/J.Yjmcc.2019.11.028  0.408
2019 Broughton KM, Khieu T, Nguyen N, Rosa M, Mohsin S, Quijada P, Wang BJ, Echeagaray OH, Kubli DA, Kim T, Firouzi F, Monsanto MM, Gude NA, Adamson RM, Dembitsky WP, ... ... Sussman MA, et al. Cardiac interstitial tetraploid cells can escape replicative senescence in rodents but not large mammals. Communications Biology. 2: 205. PMID 31925014 DOI: 10.1038/s42003-019-0453-z  0.339
2019 Wang BJ, Alvarez R, Muliono A, Sengphanith S, Monsanto MM, Weeks J, Sacripanti R, Sussman MA. Adaptation within embryonic and neonatal heart environment reveals alternative fates for adult c-kit cardiac interstitial cells. Stem Cells Translational Medicine. PMID 31891237 DOI: 10.1002/Sctm.19-0277  0.433
2019 Broughton KM, Sussman MA. Cardiac tissue engineering therapeutic products to enhance myocardial contractility. Journal of Muscle Research and Cell Motility. PMID 31863324 DOI: 10.1007/S10974-019-09570-6  0.361
2019 Murphy JF, Mayourian J, Stillitano F, Munawar S, Broughton KM, Agullo-Pascual E, Sussman MA, Hajjar RJ, Costa KD, Turnbull IC. Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues. Stem Cell Research & Therapy. 10: 373. PMID 31801634 DOI: 10.1186/S13287-019-1486-4  0.418
2019 Gude NA, Sussman MA. Cardiac regenerative therapy: Many paths to repair. Trends in Cardiovascular Medicine. PMID 31515053 DOI: 10.1016/J.Tcm.2019.08.009  0.466
2019 Echeagaray O, Sussman MA. Transcribing the heart: faithfully interpreting cardiac transcriptional insights. Regenerative Medicine. PMID 31464566 DOI: 10.2217/Rme-2019-0063  0.411
2019 Broughton KM, Sussman MA. Adult Cardiomyocyte Cell Cycle Detour: Off-ramp to Quiescent Destinations. Trends in Endocrinology and Metabolism: Tem. PMID 31262545 DOI: 10.1016/J.Tem.2019.05.006  0.361
2019 Broughton K, Korski K, Echeagaray O, Adamson R, Dembitsky W, Lu Z, Schaefer E, Sussman MA. Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells. Gene Therapy. PMID 31239537 DOI: 10.1038/S41434-019-0084-5  0.427
2019 Broughton KM, Khieu T, Nguyen N, Rosa M, Mohsin S, Quijada P, Wang BJ, Echeagaray OH, Kubli DA, Kim T, Firouzi F, Monsanto MM, Gude NA, Adamson RM, Dembitsky WP, ... ... Sussman MA, et al. Cardiac interstitial tetraploid cells can escape replicative senescence in rodents but not large mammals. Communications Biology. 2: 205. PMID 31231694 DOI: 10.1038/s42003-019-0453-z  0.339
2019 Sussman MA. Cardiac nonmyocyte subpopulations: a secular congregation. Regenerative Medicine. PMID 31115258 DOI: 10.2217/Rme-2019-0053  0.393
2019 Lampert MA, Orogo AM, Najor RH, Hammerling BC, Leon LJ, Wang BJ, Kim T, Sussman MA, Gustafsson ÅB. BNIP3L/NIX and FUNDC1-Mediated Mitophagy is Required for Mitochondrial Network Remodeling during Cardiac Progenitor Cell Differentiation. Autophagy. PMID 30741592 DOI: 10.1080/15548627.2019.1580095  0.413
2019 Korski KI, Kubli DA, Wang BJ, Khalafalla FG, Monsanto MM, Firouzi F, Echeagaray OH, Kim T, Adamson RM, Dembitsky WP, Gustafsson ÅB, Sussman MA. Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human c-Kit+ Cardiac Progenitor Cells. Stem Cells (Dayton, Ohio). PMID 30629785 DOI: 10.1002/Stem.2970  0.336
2019 Broughton KM, Ebeid D, Esquer C, Wang B, Moshref M, Sussman M. Abstract 401: Polyploidy Increases in Murine Cardiomyocytes Following Myocardial Infarction Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.401  0.323
2018 Jr RA, Wang BJ, Quijada PJ, Avitabile D, Ho T, Shaitrit M, Chavarria M, Firouzi F, Ebeid D, Monsanto MM, Navarrette N, Moshref M, Siddiqui S, Broughton KM, Bailey BA, ... ... Sussman MA, et al. Cardiomyocyte cell cycle dynamics and proliferation revealed through cardiac-specific transgenesis of fluorescent ubiquitinated cell cycle indicator (FUCCI). Journal of Molecular and Cellular Cardiology. PMID 30571978 DOI: 10.1016/J.Yjmcc.2018.12.007  0.412
2018 Kim T, Echeagaray OH, Wang BJ, Casillas A, Broughton KM, Kim BH, Sussman MA. In situ transcriptome characteristics are lost following culture adaptation of adult cardiac stem cells. Scientific Reports. 8: 12060. PMID 30104715 DOI: 10.1038/S41598-018-30551-1  0.378
2018 Gude NA, Broughton KM, Firouzi F, Sussman MA. Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence. Nature Reviews. Cardiology. PMID 30054574 DOI: 10.1038/S41569-018-0061-5  0.403
2018 Broughton KM, Sussman MA. Enhancement Strategies for Cardiac Regenerative Cell Therapy: Focus on Adult Stem Cells. Circulation Research. 123: 177-187. PMID 29976686 DOI: 10.1161/Circresaha.118.311207  0.38
2018 Khalafalla FG, Sussman MA. Cardiac progenitor cell ion currents: Revealing a little more on the lesser known. The Journal of Physiology. PMID 29676466 DOI: 10.1113/Jp276132  0.379
2018 Broughton KM, Wang BJ, Firouzi F, Khalafalla F, Dimmeler S, Fernandez-Aviles F, Sussman MA. Mechanisms of Cardiac Repair and Regeneration. Circulation Research. 122: 1151-1163. PMID 29650632 DOI: 10.1161/Circresaha.117.312586  0.365
2018 Gude NA, Firouzi F, Broughton KM, Ilves K, Nguyen KP, Payne CR, Sacchi V, Monsanto MM, Casillas AR, Khalafalla FG, Wang BJ, Ebeid D, Alvarez R, Dembitsky WP, Bailey BA, ... ... Sussman MA, et al. Cardiac c-Kit Biology Revealed by Inducible Transgenesis. Circulation Research. PMID 29636378 DOI: 10.1161/Circresaha.117.311828  0.396
2018 Matsumoto C, Jiang Y, Emathinger J, Quijada P, Nguyen N, De La Torre A, Moshref M, Nguyen J, Levinson AB, Shin M, Sussman MA, Hariharan N. Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate. Stem Cells (Dayton, Ohio). PMID 29441645 DOI: 10.1002/Stem.2793  0.401
2018 Kubli DA, Korski KI, Sussman MA. Abstract 468: Mitochondrial Dysfunction and Senescence of Human Cardiac Progenitor Cells Are Prevented by Hypoxic Culture Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.468  0.388
2018 Matsumoto C, Hua T, Sussman M, Hariharan N. Abstract 353: Nucleolar Enlargement and Perturbed Ribosome Biogenesis Are Cellular Hallmarks of Cardiac Aging Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.353  0.365
2018 Hariharan N, Matsumoto C, Jiang Y, Sussman M. Abstract 203: Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.203  0.391
2018 Broughton KM, Yaareb D, Esquer CY, Pompilio G, Sussman MA. Abstract 200: Engineering Evolution: Tetraploidization of Human Cardiac Stem Cells to Enhance Functional Activity Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.200  0.393
2018 Matsumoto C, Grayda J, Hua T, Sussman M, Hariharan N. Nucleolar Enlargement and Perturbed Ribosome Biogenesis Are Cellular Hallmarks of Cardiac Aging Journal of Molecular and Cellular Cardiology. 124: 114-115. DOI: 10.1016/J.Yjmcc.2018.07.094  0.368
2018 Kubli D, Korski K, Sussman M. Mitochondrial Dysfunction and Senescence of Human Cardiac Progenitor Cells Are Prevented by Hypoxic Culture Journal of Molecular and Cellular Cardiology. 124: 103-104. DOI: 10.1016/J.Yjmcc.2018.07.065  0.389
2018 Monsanto M, Wang B, Ehrenberg Z, Alvarez R, Sussman M. CardioClusters: Enhancing Stem Cell Engraftment and Myocardial Repair Journal of Molecular and Cellular Cardiology. 124: 85. DOI: 10.1016/J.Yjmcc.2018.07.014  0.354
2018 Alvarez R, Quijada P, Wang B, Shaitrit M, Ho T, Gude N, Sussman M. Cardiomyocyte Biology Revealed by Fluorescence Ubiquitination-based Cell Cycle Indicators (FUCCI) Journal of Molecular and Cellular Cardiology. 124: 84. DOI: 10.1016/J.Yjmcc.2018.07.011  0.307
2018 Wang B, Muliono A, Alvarez R, Sacripanti R, Sussman M. Cardiac Progenitor Cell Fate in Embryonic and Neonatal Environments Journal of Molecular and Cellular Cardiology. 124: 83. DOI: 10.1016/J.Yjmcc.2018.07.010  0.435
2017 Kubli DA, Sussman MA. Editorial commentary: Mitochondrial autophagy in cardiac aging is all fluxed up. Trends in Cardiovascular Medicine. PMID 29277287 DOI: 10.1016/J.Tcm.2017.12.008  0.331
2017 Sacchi V, Wang BJ, Kubli D, Martinez AS, Jin JK, Alvarez R, Hariharan N, Glembotski C, Uchida T, Malter JS, Yang Y, Gross P, Zhang C, Houser S, Rota M, ... Sussman MA, et al. Peptidyl-Prolyl Isomerase 1 Regulates Ca(2+) Handling by Modulating Sarco(Endo)Plasmic Reticulum Calcium ATPase and Na(2+)/Ca(2+) Exchanger 1 Protein Levels and Function. Journal of the American Heart Association. 6. PMID 29018025 DOI: 10.1161/Jaha.117.006837  0.346
2017 Khalafalla FG, Kayani W, Kassab A, Ilves K, Monsanto MM, Alvarez R, Chavarria M, Norman B, Dembitsky WP, Sussman MA. Empowering human cardiac progenitor cells by P2Y14 nucleotide receptor overexpression. The Journal of Physiology. PMID 28980705 DOI: 10.1113/Jp274980  0.379
2017 Khalafalla FG, Greene SR, Khan H, Ilves K, Monsanto MM, Alvarez R, Chavarria M, Nguyen JH, Norman B, Dembitsky WP, Sussman MA. P2Y2 Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling. Circulation Research. PMID 28923792 DOI: 10.1161/Circresaha.117.310812  0.432
2017 Sussman MA. Cardiac Stem Cells: Working Independently Together. Journal of the American College of Cardiology. 70: 742-744. PMID 28774380 DOI: 10.1016/J.Jacc.2017.06.044  0.414
2017 Eschenhagen T, Bolli R, Braun T, Field LJ, Fleischmann BK, Frisén J, Giacca M, Hare JM, Houser SR, Lee RT, Marbán E, Martin JF, Molkentin JD, Murry CE, Riley PR, ... ... Sussman MA, et al. Cardiomyocyte Regeneration: A Consensus Statement. Circulation. PMID 28684531 DOI: 10.1161/Circulationaha.117.029343  0.378
2017 Gude NA, Sussman MA. Chasing c-Kit through the heart: Taking a broader view. Pharmacological Research. PMID 28627370 DOI: 10.1016/J.Phrs.2017.06.007  0.461
2017 Monsanto MM, Wang BJ, Sussman MA. Synthetic MSC? Nothing Beats the Real Thing. Circulation Research. 120: 1694-1695. PMID 28546347 DOI: 10.1161/Circresaha.117.310986  0.41
2017 Monsanto MM, White KS, Kim T, Wang BJ, Fisher K, Ilves K, Khalafalla FG, Casillas A, Broughton K, Mohsin S, Dembitsky WP, Sussman MA. Concurrent Isolation of Three Distinct Cardiac Stem Cell Populations from a Single Human Heart Biopsy. Circulation Research. PMID 28446444 DOI: 10.1161/Circresaha.116.310494  0.424
2017 Kubli DA, Sussman MA. Eat, Breathe, ROS: Controlling Stem Cell Fate Through Metabolism. Expert Review of Cardiovascular Therapy. PMID 28406333 DOI: 10.1080/14779072.2017.1319278  0.365
2017 Liu N, Wang BJ, Broughton KM, Alvarez R, Siddiqi S, Loaiza R, Nguyen N, Quijada P, Gude N, Sussman MA. PIM1-minicircle as a therapeutic treatment for myocardial infarction. Plos One. 12: e0173963. PMID 28323876 DOI: 10.1371/Journal.Pone.0173963  0.412
2017 Khalafalla F, Kayani W, Kassab A, Ilves K, Alvarez R, Chavarria M, Norman B, Sussman M. P2Y 14 nucleotide receptor overexpression: Letting blind cardiac progenitor cells 'see' again Journal of Molecular and Cellular Cardiology. 112: 139. DOI: 10.1016/J.Yjmcc.2017.07.029  0.396
2017 Wang B, Muliono A, Alvarez R, Sussman M. Cardiac Progenitor Cell Lineage Tracing During Embryonic Cardiomyogenesis Journal of Molecular and Cellular Cardiology. 112: 138. DOI: 10.1016/J.Yjmcc.2017.07.027  0.445
2016 Broughton KM, Sussman MA. Myocardial Regeneration for Humans - Modifying Biology and Manipulating Evolution. Circulation Journal : Official Journal of the Japanese Circulation Society. PMID 28025465 DOI: 10.1253/Circj.Cj-16-1228  0.384
2016 Kulandavelu S, Karantalis V, Fritsch J, Hatzistergos KE, Loescher VY, McCall F, Wang B, Bagno L, Golpanian S, Wolf A, Grenet J, Williams A, Kupin A, Rosenfeld A, Mohsin S, ... Sussman MA, et al. Pim1 Kinase Overexpression Enhances ckit(+) Cardiac Stem Cell Cardiac Repair Following Myocardial Infarction in Swine. Journal of the American College of Cardiology. 68: 2454-2464. PMID 27908351 DOI: 10.1016/J.Jacc.2016.09.925  0.464
2016 Doroudgar S, Quijada P, Konstandin M, Ilves K, Broughton K, Khalafalla FG, Casillas A, Nguyen K, Gude N, Toko H, Ornelas L, Thuerauf DJ, Glembotski CC, Sussman MA, Völkers M. S100A4 protects the myocardium against ischemic stress. Journal of Molecular and Cellular Cardiology. PMID 27721024 DOI: 10.1016/J.Yjmcc.2016.10.001  0.386
2016 Sussman MA. Inject Me Once and Inject Me Twice. Then Inject Me Once Again. Circulation Research. 119: 580-1. PMID 27539968 DOI: 10.1161/Circresaha.116.309445  0.373
2016 Castaldi A, Chesini GP, Taylor AE, Sussman MA, Brown JH, Purcell NH. Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs. Cellular Signalling. PMID 27094722 DOI: 10.1016/J.Cellsig.2016.04.006  0.358
2016 Broughton KM, Sussman MA. Empowering Adult Stem Cells for Myocardial Regeneration V2.0: Success in Small Steps. Circulation Research. 118: 867-80. PMID 26941423 DOI: 10.1161/Circresaha.115.305227  0.352
2015 Samse K, Hariharan N, Sussman MA. Personalizing cardiac regenerative therapy: at the heart of Pim1 kinase. Pharmacological Research. PMID 26563999 DOI: 10.1016/J.Phrs.2015.11.001  0.446
2015 Quijada P, Hariharan N, Cubillo JD, Bala KM, Emathinger JM, Wang BJ, Ormachea L, Bers DM, Sussman MA, Poizat C. Nuclear Calcium/Calmodulin-Dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment. The Journal of Biological Chemistry. PMID 26324717 DOI: 10.1074/Jbc.M115.657775  0.49
2015 Quijada P, Salunga HT, Hariharan N, Cubillo J, El-Sayed F, Moshref M, Bala KM, Emathinger JM, De La Torre A, Ormachea L, Alvarez R, Gude NA, Sussman MA. Cardiac Stem Cell Hybrids Enhance Myocardial Repair. Circulation Research. PMID 26228030 DOI: 10.1161/Circresaha.115.306838  0.425
2015 Wade F, Quijada P, Al-Haffar KM, Awad SM, Kunhi M, Toko H, Marashly Q, Belhaj K, Zahid I, Al-Mohanna F, Stanford SM, Alvarez R, Liu Y, Colak D, Jordan MC, ... ... Sussman M, et al. Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy. The Journal of Pathology. PMID 26213100 DOI: 10.1002/Path.4594  0.433
2015 Orogo AM, Gonzalez ER, Kubli DA, Baptista IL, Ong SB, Prolla TA, Sussman MA, Murphy AN, Gustafsson ÅB. Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival. The Journal of Biological Chemistry. PMID 26183775 DOI: 10.1074/Jbc.M115.649657  0.363
2015 Doroudgar S, Völkers M, Thuerauf DJ, Khan M, Mohsin S, Respress JL, Wang W, Gude N, Müller OJ, Wehrens XH, Sussman MA, Glembotski CC. Hrd1 and ER-Associated Protein Degradation, ERAD, Are Critical Elements of the Adaptive ER Stress Response in Cardiac Myocytes. Circulation Research. 117: 536-46. PMID 26137860 DOI: 10.1161/Circresaha.115.306993  0.333
2015 Monsanto M, Sussman MA. Myocardial Infarct Scar: Hunting Down the Responsible Cells, But Then What? Journal of the American College of Cardiology. 65: 2067-9. PMID 25975468 DOI: 10.1016/J.Jacc.2015.03.519  0.395
2015 Gude N, Joyo E, Toko H, Quijada P, Villanueva M, Hariharan N, Sacchi V, Truffa S, Joyo A, Voelkers M, Alvarez R, Sussman MA. Notch activation enhances lineage commitment and protective signaling in cardiac progenitor cells. Basic Research in Cardiology. 110: 29. PMID 25893875 DOI: 10.1007/S00395-015-0488-3  0.478
2015 Hariharan N, Sussman MA. Cardiac aging - Getting to the stem of the problem. Journal of Molecular and Cellular Cardiology. 83: 32-6. PMID 25886698 DOI: 10.1016/J.Yjmcc.2015.04.008  0.377
2015 Samse K, Emathinger J, Hariharan N, Quijada P, Ilves K, Völkers M, Ormachea L, De La Torre A, Orogo AM, Alvarez R, Din S, Mohsin S, Monsanto M, Fischer KM, Dembitsky WP, ... ... Sussman MA, et al. Functional Effect of Pim1 Depends upon Intracellular Localization in Human Cardiac Progenitor Cells. The Journal of Biological Chemistry. 290: 13935-47. PMID 25882843 DOI: 10.1074/Jbc.M114.617431  0.455
2015 Nguyen N, Sussman MA. Rejuvenating the senescent heart. Current Opinion in Cardiology. 30: 235-9. PMID 25760821 DOI: 10.1097/Hco.0000000000000161  0.42
2015 Quijada P, Sussman MA. Circulating around the tissue: hematopoietic cell-based fusion versus transdifferentiation. Circulation Research. 116: 563-5. PMID 25677514 DOI: 10.1161/Circresaha.115.305820  0.349
2015 Hariharan N, Quijada P, Mohsin S, Joyo A, Samse K, Monsanto M, De La Torre A, Avitabile D, Ormachea L, McGregor MJ, Tsai EJ, Sussman MA. Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging. Journal of the American College of Cardiology. 65: 133-47. PMID 25593054 DOI: 10.1016/J.Jacc.2014.09.086  0.426
2015 Awad S, Al-Haffar KM, Marashly Q, Quijada P, Kunhi M, Al-Yacoub N, Wade FS, Mohammed SF, Al-Dayel F, Sutherland G, Assiri A, Sussman M, Bers D, Al-Habeeb W, Poizat C. Control of histone H3 phosphorylation by CaMKIIδ in response to haemodynamic cardiac stress. The Journal of Pathology. 235: 606-18. PMID 25421395 DOI: 10.1002/Path.4489  0.434
2014 Siddiqi S, Sussman MA. The heart: mostly postmitotic or mostly premitotic? Myocyte cell cycle, senescence, and quiescence. The Canadian Journal of Cardiology. 30: 1270-8. PMID 25442430 DOI: 10.1016/J.Cjca.2014.08.014  0.402
2014 Sussman MA, Puceat M. Response to letter regarding article, "Embryonic stem cell-derived cardiac myocytes are not ready for human trials". Circulation Research. 115: e30-1. PMID 25342772 DOI: 10.1161/Circresaha.114.305341  0.332
2014 Quijada P, Sussman MA. Making it stick: chasing the optimal stem cells for cardiac regeneration. Expert Review of Cardiovascular Therapy. 12: 1275-88. PMID 25340282 DOI: 10.1586/14779072.2014.972941  0.41
2014 Gaetani R, Feyen DA, Doevendans PA, Gremmels H, Forte E, Fledderus JO, Ramjankhan FZ, Messina E, Sussman MA, Giacomello A, Sluijter JP. Different types of cultured human adult cardiac progenitor cells have a high degree of transcriptome similarity. Journal of Cellular and Molecular Medicine. 18: 2147-51. PMID 25311343 DOI: 10.1111/Jcmm.12458  0.402
2014 Panopoulos A, Pacios-Bras C, Choi J, Yenjerla M, Sussman MA, Fotedar R, Margolis RL. Failure of cell cleavage induces senescence in tetraploid primary cells. Molecular Biology of the Cell. 25: 3105-18. PMID 25143403 DOI: 10.1091/Mbc.E14-03-0844  0.373
2014 Sin J, Puccini JM, Huang C, Konstandin MH, Gilbert PE, Sussman MA, Gottlieb RA, Feuer R. The impact of juvenile coxsackievirus infection on cardiac progenitor cells and postnatal heart development. Plos Pathogens. 10: e1004249. PMID 25079373 DOI: 10.1371/Journal.Ppat.1004249  0.397
2014 Hariharan N, Sussman MA. Pin1: a molecular orchestrator in the heart. Trends in Cardiovascular Medicine. 24: 256-62. PMID 25070718 DOI: 10.1016/J.Tcm.2014.05.010  0.382
2014 Anderson ME, Goldhaber J, Houser SR, Puceat M, Sussman MA. Embryonic stem cell-derived cardiac myocytes are not ready for human trials. Circulation Research. 115: 335-8. PMID 24935962 DOI: 10.1161/Circresaha.114.304616  0.425
2014 Din S, Konstandin MH, Johnson B, Emathinger J, Völkers M, Toko H, Collins B, Ormachea L, Samse K, Kubli DA, De La Torre A, Kraft AS, Gustafsson AB, Kelly DP, Sussman MA. Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases. Circulation Research. 115: 376-87. PMID 24916111 DOI: 10.1161/Circresaha.115.304441  0.351
2014 Hariharan N, Sussman MA. Stressing on the nucleolus in cardiovascular disease. Biochimica Et Biophysica Acta. 1842: 798-801. PMID 24514103 DOI: 10.1016/J.Bbadis.2013.09.016  0.325
2014 Toko H, Hariharan N, Konstandin MH, Ormachea L, McGregor M, Gude NA, Sundararaman B, Joyo E, Joyo AY, Collins B, Din S, Mohsin S, Uchida T, Sussman MA. Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells. The Journal of Biological Chemistry. 289: 5348-56. PMID 24375406 DOI: 10.1074/Jbc.M113.526442  0.456
2014 McGregor M, Hariharan N, Joyo AY, Margolis RL, Sussman MA. CENP-A is essential for cardiac progenitor cell proliferation. Cell Cycle (Georgetown, Tex.). 13: 739-48. PMID 24362315 DOI: 10.4161/Cc.27549  0.437
2014 Mohsin S, Wu JC, Sussman MA. Predicting the future with stem cells. Circulation. 129: 136-8. PMID 24249719 DOI: 10.1161/Circulationaha.113.007045  0.372
2014 Khan M, Mohsin S, Toko H, Alkatib M, Nguyen J, Truffa S, Gude N, Chuprun K, Tilley DG, Koch WJ, Sussman MA. Cardiac progenitor cells engineered with βARKct have enhanced β-adrenergic tolerance. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 178-85. PMID 24002692 DOI: 10.1038/Mt.2013.200  0.409
2013 Siddiqi S, Sussman MA. Cardiac Hegemony of Senescence. Current Translational Geriatrics and Experimental Gerontology Reports. 2. PMID 24349878 DOI: 10.1007/S13670-013-0064-3  0.444
2013 Völkers M, Sussman M. mTOR/PRAS40 interaction: hypertrophy or proliferation. Cell Cycle (Georgetown, Tex.). 12: 3579-80. PMID 24131922 DOI: 10.4161/Cc.26822  0.441
2013 Mohsin S, Khan M, Nguyen J, Alkatib M, Siddiqi S, Hariharan N, Wallach K, Monsanto M, Gude N, Dembitsky W, Sussman MA. Rejuvenation of human cardiac progenitor cells with Pim-1 kinase. Circulation Research. 113: 1169-79. PMID 24044948 DOI: 10.1161/Circresaha.113.302302  0.461
2013 Völkers M, Konstandin MH, Doroudgar S, Toko H, Quijada P, Din S, Joyo A, Ornelas L, Samse K, Thuerauf DJ, Gude N, Glembotski CC, Sussman MA. Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage. Circulation. 128: 2132-44. PMID 24008870 DOI: 10.1161/Circulationaha.113.003638  0.324
2013 Siddiqi S, Sussman MA. Cell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase. Expert Review of Cardiovascular Therapy. 11: 949-57. PMID 23984924 DOI: 10.1586/14779072.2013.814830  0.429
2013 Konstandin MH, Völkers M, Collins B, Quijada P, Quintana M, De La Torre A, Ormachea L, Din S, Gude N, Toko H, Sussman MA. Fibronectin contributes to pathological cardiac hypertrophy but not physiological growth. Basic Research in Cardiology. 108: 375. PMID 23912225 DOI: 10.1007/S00395-013-0375-8  0.396
2013 Völkers M, Toko H, Doroudgar S, Din S, Quijada P, Joyo AY, Ornelas L, Joyo E, Thuerauf DJ, Konstandin MH, Gude N, Glembotski CC, Sussman MA. Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1. Proceedings of the National Academy of Sciences of the United States of America. 110: 12661-6. PMID 23842089 DOI: 10.1073/Pnas.1301455110  0.39
2013 Thomas RL, Roberts DJ, Kubli DA, Lee Y, Quinsay MN, Owens JB, Fischer KM, Sussman MA, Miyamoto S, Gustafsson ÅB. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes & Development. 27: 1365-77. PMID 23788623 DOI: 10.1101/Gad.215871.113  0.416
2013 Konstandin MH, Toko H, Gastelum GM, Quijada P, De La Torre A, Quintana M, Collins B, Din S, Avitabile D, Völkers M, Gude N, Fässler R, Sussman MA. Fibronectin is essential for reparative cardiac progenitor cell response after myocardial infarction. Circulation Research. 113: 115-25. PMID 23652800 DOI: 10.1161/Circresaha.113.301152  0.414
2013 Din S, Mason M, Völkers M, Johnson B, Cottage CT, Wang Z, Joyo AY, Quijada P, Erhardt P, Magnuson NS, Konstandin MH, Sussman MA. Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation. Proceedings of the National Academy of Sciences of the United States of America. 110: 5969-74. PMID 23530233 DOI: 10.1073/Pnas.1213294110  0.346
2013 Toko H, Konstandin MH, Doroudgar S, Ormachea L, Joyo E, Joyo AY, Din S, Gude NA, Collins B, Völkers M, Thuerauf DJ, Glembotski CC, Chen CH, Lu KP, Müller OJ, ... ... Sussman MA, et al. Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1. Circulation Research. 112: 1244-52. PMID 23487407 DOI: 10.1161/Circresaha.113.301084  0.41
2013 Khan M, Mohsin S, Avitabile D, Siddiqi S, Nguyen J, Wallach K, Quijada P, McGregor M, Gude N, Alvarez R, Tilley DG, Koch WJ, Sussman MA. β-Adrenergic regulation of cardiac progenitor cell death versus survival and proliferation. Circulation Research. 112: 476-86. PMID 23243208 DOI: 10.1161/Circresaha.112.280735  0.413
2013 Williams AR, Hatzistergos KE, Addicott B, McCall F, Carvalho D, Suncion V, Morales AR, Da Silva J, Sussman MA, Heldman AW, Hare JM. Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction. Circulation. 127: 213-23. PMID 23224061 DOI: 10.1161/Circulationaha.112.131110  0.412
2012 Tufan H, Zhang XH, Haghshenas N, Sussman MA, Cleemann L, Morad M. Cardiac progenitor cells engineered with Pim-1 (CPCeP) develop cardiac phenotypic electrophysiological properties as they are co-cultured with neonatal myocytes. Journal of Molecular and Cellular Cardiology. 53: 695-706. PMID 23010478 DOI: 10.1016/J.Yjmcc.2012.08.008  0.351
2012 Cottage CT, Neidig L, Sundararaman B, Din S, Joyo AY, Bailey B, Gude N, Hariharan N, Sussman MA. Increased mitotic rate coincident with transient telomere lengthening resulting from pim-1 overexpression in cardiac progenitor cells. Stem Cells (Dayton, Ohio). 30: 2512-22. PMID 22915504 DOI: 10.1002/Stem.1211  0.468
2012 Mohsin S, Khan M, Toko H, Bailey B, Cottage CT, Wallach K, Nag D, Lee A, Siddiqi S, Lan F, Fischer KM, Gude N, Quijada P, Avitabile D, Truffa S, ... ... Sussman MA, et al. Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. Journal of the American College of Cardiology. 60: 1278-87. PMID 22841153 DOI: 10.1016/J.Jacc.2012.04.047  0.436
2012 Bailey B, Fransioli J, Gude NA, Alvarez R, Zhang X, Zhan X, Gustafsson ÅB, Sussman MA. Sca-1 knockout impairs myocardial and cardiac progenitor cell function. Circulation Research. 111: 750-60. PMID 22800687 DOI: 10.1161/Circresaha.112.274662  0.451
2012 Quijada P, Toko H, Fischer KM, Bailey B, Reilly P, Hunt KD, Gude NA, Avitabile D, Sussman MA. Preservation of myocardial structure is enhanced by pim-1 engineering of bone marrow cells. Circulation Research. 111: 77-86. PMID 22619278 DOI: 10.1161/Circresaha.112.265207  0.405
2012 Houser SR, Margulies KB, Murphy AM, Spinale FG, Francis GS, Prabhu SD, Rockman HA, Kass DA, Molkentin JD, Sussman MA, Koch WJ, Koch W. Animal models of heart failure: a scientific statement from the American Heart Association. Circulation Research. 111: 131-50. PMID 22595296 DOI: 10.1161/Res.0B013E3182582523  0.312
2012 Sussman MA. Myocardial Isl(+)land: a place with lots of rhythm, but no beat. Circulation Research. 110: 1267-9. PMID 22581917 DOI: 10.1161/Circresaha.112.268995  0.466
2012 Gude N, Sussman M. Notch signaling and cardiac repair. Journal of Molecular and Cellular Cardiology. 52: 1226-32. PMID 22465038 DOI: 10.1016/J.Yjmcc.2012.03.007  0.424
2012 Sundararaman B, Avitabile D, Konstandin MH, Cottage CT, Gude N, Sussman MA. Asymmetric chromatid segregation in cardiac progenitor cells is enhanced by Pim-1 kinase. Circulation Research. 110: 1169-73. PMID 22441844 DOI: 10.1161/Circresaha.112.267716  0.431
2012 Völkers M, Dolatabadi N, Gude N, Most P, Sussman MA, Hassel D. Orai1 deficiency leads to heart failure and skeletal myopathy in zebrafish. Journal of Cell Science. 125: 287-94. PMID 22302996 DOI: 10.1242/Jcs.090464  0.413
2012 Ruller CM, Tabor-Godwin JM, Van Deren DA, Robinson SM, Maciejewski S, Gluhm S, Gilbert PE, An N, Gude NA, Sussman MA, Whitton JL, Feuer R. Neural stem cell depletion and CNS developmental defects after enteroviral infection. The American Journal of Pathology. 180: 1107-20. PMID 22214838 DOI: 10.1016/J.Ajpath.2011.11.016  0.319
2011 Mohsin S, Siddiqi S, Collins B, Sussman MA. Empowering adult stem cells for myocardial regeneration. Circulation Research. 109: 1415-28. PMID 22158649 DOI: 10.1161/Circresaha.111.243071  0.451
2011 Sussman MA, Völkers M, Fischer K, Bailey B, Cottage CT, Din S, Gude N, Avitabile D, Alvarez R, Sundararaman B, Quijada P, Mason M, Konstandin MH, Malhowski A, Cheng Z, et al. Myocardial AKT: the omnipresent nexus. Physiological Reviews. 91: 1023-70. PMID 21742795 DOI: 10.1152/Physrev.00024.2010  0.384
2011 Meloche J, Paulin R, Courboulin A, Lambert C, Barrier M, Bonnet P, Bisserier M, Roy M, Sussman MA, Agharazii M, Bonnet S. RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2114-24. PMID 21680901 DOI: 10.1161/Atvbaha.111.230573  0.311
2011 Sussman MA. Curiosity killed the cat and found new myocytes. Circulation Research. 108: 1158-9. PMID 21566219 DOI: 10.1161/Circresaha.111.245571  0.39
2011 Avitabile D, Bailey B, Cottage CT, Sundararaman B, Joyo A, McGregor M, Gude N, Truffa S, Zarrabi A, Konstandin M, Khan M, Mohsin S, Völkers M, Toko H, Mason M, ... ... Sussman MA, et al. Nucleolar stress is an early response to myocardial damage involving nucleolar proteins nucleostemin and nucleophosmin. Proceedings of the National Academy of Sciences of the United States of America. 108: 6145-50. PMID 21444791 DOI: 10.1073/Pnas.1017935108  0.398
2011 Fischer KM, Din S, Gude N, Konstandin MH, Wu W, Quijada P, Sussman MA. Cardiac progenitor cell commitment is inhibited by nuclear Akt expression. Circulation Research. 108: 960-70. PMID 21350213 DOI: 10.1161/Circresaha.110.237156  0.458
2011 Fischer KM, Cottage CT, Konstandin MH, Völkers M, Khan M, Sussman MA. Pim-1 kinase inhibits pathological injury by promoting cardioprotective signaling. Journal of Molecular and Cellular Cardiology. 51: 554-8. PMID 21255581 DOI: 10.1016/J.Yjmcc.2011.01.004  0.438
2011 Cheng Z, Völkers M, Din S, Avitabile D, Khan M, Gude N, Mohsin S, Bo T, Truffa S, Alvarez R, Mason M, Fischer KM, Konstandin MH, Zhang XK, Heller Brown J, ... Sussman MA, et al. Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis. European Heart Journal. 32: 2179-88. PMID 21228009 DOI: 10.1093/Eurheartj/Ehq496  0.331
2010 Miyamoto S, Purcell NH, Smith JM, Gao T, Whittaker R, Huang K, Castillo R, Glembotski CC, Sussman MA, Newton AC, Brown JH. PHLPP-1 negatively regulates Akt activity and survival in the heart. Circulation Research. 107: 476-84. PMID 20576936 DOI: 10.1161/Circresaha.109.215020  0.387
2010 Tabor-Godwin JM, Ruller CM, Bagalso N, An N, Pagarigan RR, Harkins S, Gilbert PE, Kiosses WB, Gude NA, Cornell CT, Doran KS, Sussman MA, Whitton JL, Feuer R. A novel population of myeloid cells responding to coxsackievirus infection assists in the dissemination of virus within the neonatal CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8676-91. PMID 20573913 DOI: 10.1523/Jneurosci.1860-10.2010  0.338
2010 Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, ... ... Sussman MA, et al. Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circulation Research. 106: 1265-74. PMID 20203306 DOI: 10.1161/Circresaha.109.212035  0.336
2010 Voelkers M, Salz M, Herzog N, Frank D, Dolatabadi N, Frey N, Gude N, Friedrich O, Koch WJ, Katus HA, Sussman MA, Most P. Orai1 and Stim1 regulate normal and hypertrophic growth in cardiomyocytes Journal of Molecular and Cellular Cardiology. 48: 1329-1334. PMID 20138887 DOI: 10.1016/J.Yjmcc.2010.01.020  0.366
2010 Adam O, Lavall D, Theobald K, Hohl M, Grube M, Ameling S, Sussman MA, Rosenkranz S, Kroemer HK, Schäfers HJ, Böhm M, Laufs U. Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation. Journal of the American College of Cardiology. 55: 469-80. PMID 20117462 DOI: 10.1016/J.Jacc.2009.08.064  0.301
2010 Huang C, Zhang X, Ramil JM, Rikka S, Kim L, Lee Y, Gude NA, Thistlethwaite PA, Sussman MA, Gottlieb RA, Gustafsson AB. Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice. Circulation. 121: 675-83. PMID 20100968 DOI: 10.1161/Circulationaha.109.902221  0.356
2010 Cottage CT, Bailey B, Fischer KM, Avitabile D, Avitable D, Collins B, Tuck S, Quijada P, Gude N, Alvarez R, Muraski J, Sussman MA. Cardiac progenitor cell cycling stimulated by pim-1 kinase. Circulation Research. 106: 891-901. PMID 20075333 DOI: 10.1161/Circresaha.109.208629  0.406
2010 Tufan H, Cleemann L, Sussman M, Morad M. Ca2+ Transients In Pim-1 Transfected Cardiac Stem Cells Co-Cultured With Rat Neonatal Cardiomyocytes Biophysical Journal. 98: 134a. DOI: 10.1016/J.Bpj.2009.12.725  0.351
2009 Bailey B, Izarra A, Alvarez R, Fischer KM, Cottage CT, Quijada P, Díez-Juan A, Sussman MA. Cardiac stem cell genetic engineering using the alphaMHC promoter. Regenerative Medicine. 4: 823-33. PMID 19903002 DOI: 10.2217/Rme.09.51  0.446
2009 Fischer KM, Cottage CT, Wu W, Din S, Gude NA, Avitabile D, Quijada P, Collins BL, Fransioli J, Sussman MA. Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase. Circulation. 120: 2077-87. PMID 19901187 DOI: 10.1161/Circulationaha.109.884403  0.428
2009 Sussman MA. Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyte. Expert Review of Cardiovascular Therapy. 7: 929-38. PMID 19673671 DOI: 10.1586/Erc.09.48  0.346
2009 Miyamoto S, Rubio M, Sussman MA. Nuclear and mitochondrial signalling Akts in cardiomyocytes. Cardiovascular Research. 82: 272-85. PMID 19279164 DOI: 10.1093/Cvr/Cvp087  0.334
2009 Rubio M, Avitabile D, Fischer K, Emmanuel G, Gude N, Miyamoto S, Mishra S, Schaefer EM, Brown JH, Sussman MA. Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes. Journal of Molecular and Cellular Cardiology. 47: 96-103. PMID 19269295 DOI: 10.1016/J.Yjmcc.2009.02.022  0.366
2009 Whittaker R, Glassy MS, Gude N, Sussman MA, Gottlieb RA, Glembotski CC. Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1633-42. PMID 19252088 DOI: 10.1152/Ajpheart.01227.2008  0.365
2009 Sussman MA. Developing hearts need their SPEG. Circulation. 119: 213-4. PMID 19153282 DOI: 10.1161/Circulationaha.108.827949  0.402
2008 Sussman MA. Showing up isn't enough for vascularization: persistence is essential. Circulation Research. 103: 1200-1. PMID 19028918 DOI: 10.1161/Circresaha.108.189076  0.345
2008 McKeown CR, Nowak RB, Moyer J, Sussman MA, Fowler VM. Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development. Circulation Research. 103: 1241-8. PMID 18927466 DOI: 10.1161/Circresaha.108.178749  0.421
2008 Tadimalla A, Belmont PJ, Thuerauf DJ, Glassy MS, Martindale JJ, Gude N, Sussman MA, Glembotski CC. Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart. Circulation Research. 103: 1249-58. PMID 18927462 DOI: 10.1161/Circresaha.108.180679  0.431
2008 Muraski JA, Fischer KM, Wu W, Cottage CT, Quijada P, Mason M, Din S, Gude N, Alvarez R, Rota M, Kajstura J, Wang Z, Schaefer E, Chen X, MacDonnel S, ... ... Sussman MA, et al. Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload. Proceedings of the National Academy of Sciences of the United States of America. 105: 13889-94. PMID 18784362 DOI: 10.1073/Pnas.0709135105  0.445
2008 Siddiqi S, Gude N, Hosoda T, Muraski J, Rubio M, Emmanuel G, Fransioli J, Vitale S, Parolin C, D'Amario D, Schaefer E, Kajstura J, Leri A, Anversa P, Sussman MA. Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge. Circulation Research. 103: 89-97. PMID 18519946 DOI: 10.1161/Circresaha.107.169334  0.454
2008 Sussman MA, Murry CE. Bones of contention: marrow-derived cells in myocardial regeneration. Journal of Molecular and Cellular Cardiology. 44: 950-3. PMID 18440020 DOI: 10.1016/J.Yjmcc.2008.03.007  0.321
2008 Gude NA, Emmanuel G, Wu W, Cottage CT, Fischer K, Quijada P, Muraski JA, Alvarez R, Rubio M, Schaefer E, Sussman MA. Activation of Notch-mediated protective signaling in the myocardium. Circulation Research. 102: 1025-35. PMID 18369158 DOI: 10.1161/Circresaha.107.164749  0.393
2008 Belmont PJ, Tadimalla A, Chen WJ, Martindale JJ, Thuerauf DJ, Marcinko M, Gude N, Sussman MA, Glembotski CC. Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene. The Journal of Biological Chemistry. 283: 14012-21. PMID 18319259 DOI: 10.1074/Jbc.M709776200  0.344
2008 Fransioli J, Bailey B, Gude NA, Cottage CT, Muraski JA, Emmanuel G, Wu W, Alvarez R, Rubio M, Ottolenghi S, Schaefer E, Sussman MA. Evolution of the c-kit-positive cell response to pathological challenge in the myocardium. Stem Cells (Dayton, Ohio). 26: 1315-24. PMID 18308948 DOI: 10.1634/Stemcells.2007-0751  0.371
2007 Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, ... ... Sussman MA, et al. Pim-1 regulates cardiomyocyte survival downstream of Akt Nature Medicine. 13: 1467-1475. PMID 18037896 DOI: 10.1038/Nm1671  0.392
2007 Rota M, Kajstura J, Hosoda T, Bearzi C, Vitale S, Esposito G, Iaffaldano G, Padin-Iruegas ME, Gonzalez A, Rizzi R, Small N, Muraski J, Alvarez R, Chen X, Urbanek K, ... ... Sussman MA, et al. Bone marrow cells adopt the cardiomyogenic fate in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 17783-8. PMID 17965233 DOI: 10.1073/Pnas.0706406104  0.428
2007 Sussman M. "AKT"ing lessons for stem cells: regulation of cardiac myocyte and progenitor cell proliferation. Trends in Cardiovascular Medicine. 17: 235-40. PMID 17936205 DOI: 10.1016/J.Tcm.2007.08.003  0.454
2007 Adam O, Frost G, Custodis F, Sussman MA, Schäfers HJ, Böhm M, Laufs U. Role of Rac1 GTPase activation in atrial fibrillation. Journal of the American College of Cardiology. 50: 359-67. PMID 17659204 DOI: 10.1016/J.Jacc.2007.03.041  0.349
2006 Tsujita Y, Muraski J, Shiraishi I, Kato T, Kajstura J, Anversa P, Sussman MA. Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 103: 11946-51. PMID 16882732 DOI: 10.1073/Pnas.0510138103  0.379
2006 Gude N, Muraski J, Rubio M, Kajstura J, Schaefer E, Anversa P, Sussman MA. Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population. Circulation Research. 99: 381-8. PMID 16840722 DOI: 10.1161/01.Res.0000236754.21499.1C  0.445
2006 Thuerauf DJ, Marcinko M, Gude N, Rubio M, Sussman MA, Glembotski CC. Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circulation Research. 99: 275-82. PMID 16794188 DOI: 10.1161/01.Res.0000233317.70421.03  0.422
2006 Martindale JJ, Fernandez R, Thuerauf D, Whittaker R, Gude N, Sussman MA, Glembotski CC. Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circulation Research. 98: 1186-93. PMID 16601230 DOI: 10.1161/01.Res.0000220643.65941.8D  0.354
2006 Brown JH, Del Re DP, Sussman MA. The Rac and Rho hall of fame: a decade of hypertrophic signaling hits. Circulation Research. 98: 730-42. PMID 16574914 DOI: 10.1161/01.Res.0000216039.75913.9E  0.396
2005 Rota M, Boni A, Urbanek K, Padin-Iruegas ME, Kajstura TJ, Fiore G, Kubo H, Sonnenblick EH, Musso E, Houser SR, Leri A, Sussman MA, Anversa P. Nuclear targeting of Akt enhances ventricular function and myocyte contractility. Circulation Research. 97: 1332-41. PMID 16293788 DOI: 10.1161/01.Res.0000196568.11624.Ae  0.424
2005 Kato T, Muraski J, Chen Y, Tsujita Y, Wall J, Glembotski CC, Schaefer E, Beckerle M, Sussman MA. Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt. The Journal of Clinical Investigation. 115: 2716-30. PMID 16200208 DOI: 10.1172/Jci24280  0.359
2005 Buscemi N, Murray C, Doherty-Kirby A, Lajoie G, Sussman MA, Van Eyk JE. Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 289: H2325-33. PMID 16155095 DOI: 10.1152/Ajpheart.01041.2004  0.389
2005 Steinberg SF, Sussman MA. Cardiac hypertrophy served with protein kinase Cepsilon: delta isoform substitution available at additional cost. Circulation Research. 96: 711-3. PMID 15831822 DOI: 10.1161/01.Res.0000164185.96546.82  0.4
2005 Tsujita Y, Kato T, Sussman MA. Evaluation of left ventricular function in cardiomyopathic mice by tissue Doppler and color M-mode Doppler echocardiography. Echocardiography (Mount Kisco, N.Y.). 22: 245-53. PMID 15725160 DOI: 10.1111/J.0742-2822.2005.04014.X  0.324
2005 Fowler VM, Moyer J, Nowak R, Fritz-Six K, Ferreira-Mota C, Sussman MA. Expression of Tropomodulin1 (Tmod1) in the Heart Rescues Embryonic Lethality of Tmod1 Null Mice and Results in a Mild Hemolytic Anemia Due to Absence of Tmod1 in Red Blood Cells. Blood. 106: 807-807. DOI: 10.1182/Blood.V106.11.807.807  0.379
2005 Sussman M. Cardiac Progenitor Cells: Hiding in Plain Sight Microscopy and Microanalysis. 11. DOI: 10.1017/S1431927605510353  0.449
2004 Melendez J, Turner C, Avraham H, Steinberg SF, Schaefer E, Sussman MA. Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin. The Journal of Biological Chemistry. 279: 53516-23. PMID 15322113 DOI: 10.1074/Jbc.M408475200  0.408
2004 Anversa P, Sussman MA, Bolli R. Molecular genetic advances in cardiovascular medicine: focus on the myocyte. Circulation. 109: 2832-8. PMID 15197155 DOI: 10.1161/01.Cir.0000132469.85026.46  0.455
2004 Shiraishi I, Melendez J, Ahn Y, Skavdahl M, Murphy E, Welch S, Schaefer E, Walsh K, Rosenzweig A, Torella D, Nurzynska D, Kajstura J, Leri A, Anversa P, Sussman MA. Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circulation Research. 94: 884-91. PMID 14988230 DOI: 10.1161/01.Res.0000124394.01180.Be  0.39
2004 Sussman MA, Anversa P. Myocardial aging and senescence: where have the stem cells gone? Annual Review of Physiology. 66: 29-48. PMID 14977395 DOI: 10.1146/Annurev.Physiol.66.032102.140723  0.432
2004 Torella D, Rota M, Nurzynska D, Musso E, Monsen A, Shiraishi I, Zias E, Walsh K, Rosenzweig A, Sussman MA, Urbanek K, Nadal-Ginard B, Kajstura J, Anversa P, Leri A. Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression. Circulation Research. 94: 514-24. PMID 14726476 DOI: 10.1161/01.Res.0000117306.10142.50  0.41
2003 Buscemi N, Doherty-Kirby A, Sussman MA, Lajoie G, Van Eyk JE. Proteomic analysis of Rac1 transgenic mice displaying dilated cardiomyopathy reveals an increase in creatine kinase M-chain protein abundance. Molecular and Cellular Biochemistry. 251: 145-51. PMID 14575316 DOI: 10.1007/978-1-4419-9238-3_20  0.33
2003 Sussman MA. ICER-capades: putting cardiac cyclic AMP signaling "on ice". Circulation Research. 93: 6-8. PMID 12855670 DOI: 10.1161/01.Res.0000082770.81721.44  0.351
2003 Plank DM, Yatani A, Ritsu H, Witt S, Glascock B, Lalli MJ, Periasamy M, Fiset C, Benkusky N, Valdivia HH, Sussman MA. Calcium dynamics in the failing heart: restoration by beta-adrenergic receptor blockade. American Journal of Physiology. Heart and Circulatory Physiology. 285: H305-15. PMID 12649072 DOI: 10.1152/Ajpheart.00425.2002  0.31
2003 Goldsmith EC, Carver W, McFadden A, Goldsmith JG, Price RL, Sussman M, Lorell BH, Cooper G, Borg TK. Integrin shedding as a mechanism of cellular adaptation during cardiac growth American Journal of Physiology - Heart and Circulatory Physiology. 284: H2227-H2234. PMID 12573995 DOI: 10.1152/Ajpheart.00920.2002  0.365
2003 Sayen MR, Gustafsson AB, Sussman MA, Molkentin JD, Gottlieb RA. Calcineurin transgenic mice have mitochondrial dysfunction and elevated superoxide production. American Journal of Physiology. Cell Physiology. 284: C562-70. PMID 12397029 DOI: 10.1152/Ajpcell.00336.2002  0.309
2002 Sussman MA, McCulloch A, Borg TK. Dance band on the Titanic: Biomechanical signaling in cardiac hypertrophy Circulation Research. 91: 888-898. PMID 12433833 DOI: 10.1161/01.Res.0000041680.43270.F8  0.322
2002 Melendez J, Welch S, Schaefer E, Moravec CS, Avraham S, Avraham H, Sussman MA. Activation of pyk2/related focal adhesion tyrosine kinase and focal adhesion kinase in cardiac remodeling. The Journal of Biological Chemistry. 277: 45203-10. PMID 12228222 DOI: 10.1074/Jbc.M204886200  0.381
2002 Welch S, Plank D, Witt S, Glascock B, Schaefer E, Chimenti S, Andreoli AM, Limana F, Leri A, Kajstura J, Anversa P, Sussman MA. Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice. Circulation Research. 90: 641-8. PMID 11934830 DOI: 10.1161/01.Res.0000013780.77774.75  0.411
2001 Camper-Kirby D, Welch S, Walker A, Shiraishi I, Setchell KD, Schaefer E, Kajstura J, Anversa P, Sussman MA. Myocardial Akt activation and gender: increased nuclear activity in females versus males. Circulation Research. 88: 1020-7. PMID 11375271 DOI: 10.1161/Hh1001.090858  0.349
2001 Ehler E, Horowits R, Zuppinger C, Price RL, Perriard E, Leu M, Caroni P, Sussman M, Eppenberger HM, Perriard JC. Alterations at the intercalated disk associated with the absence of muscle LIM protein. The Journal of Cell Biology. 153: 763-72. PMID 11352937 DOI: 10.1083/Jcb.153.4.763  0.349
2001 Sussman M. Cardiovascular biology. Hearts and bones. Nature. 410: 640-641. PMID 11287932 DOI: 10.1038/35070687  0.342
2001 Sussman MA. When the Thyroid Speaks, the Heart Listens Circulation Research. 89: 557-559. DOI: 10.1161/Res.89.7.557  0.395
2000 Yang J, Moravec CS, Sussman MA, DiPaola NR, Fu D, Hawthorn L, Mitchell CA, Young JB, Francis GS, McCarthy PM, Bond M. Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays Circulation. 102: 3046-3052. PMID 11120693 DOI: 10.1161/01.Cir.102.25.3046  0.379
2000 Delling U, Sussman MA, Molkentin JD. Re-evaluating sarcoplasmic reticulum function in heart failure. Nature Medicine. 6: 942-3. PMID 10973288 DOI: 10.1038/79592  0.374
2000 Babu GJ, Lalli JM, Sussman MA, Sadoshima Ji, Periasamy M. Phosphorylation of Elk-1 by MEK/ERK pathway is necessary for c-fos gene activation during cardiac myocyte hypertrophy Journal of Molecular and Cellular Cardiology. 32: 1447-1457. PMID 10900171 DOI: 10.1006/Jmcc.2000.1185  0.366
2000 Lim HW, De Windt LJ, Mante J, Kimball TR, Witt SA, Sussman MA, Molkentin JD. Reversal of cardiac hypertrophy in transgenic disease models by calcineurin inhibition. Journal of Molecular and Cellular Cardiology. 32: 697-709. PMID 10756124 DOI: 10.1006/Jmcc.2000.1113  0.432
2000 Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, Price RL, Schaefer E, Yager K. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. The Journal of Clinical Investigation. 105: 875-86. PMID 10749567 DOI: 10.1172/Jci8497  0.457
2000 Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, Witt SA, Kimball TR, Price R, Lim HW, Molkentin JD. Hypertrophic defect unmasked by calcineurin expression in asymptomatic tropomodulin overexpressing transgenic mice. Cardiovascular Research. 46: 90-101. PMID 10727657 DOI: 10.1016/S0008-6363(99)00422-8  0.309
1999 Sussman MA, Welch S, Gude N, Khoury PR, Daniels SR, Kirkpatrick D, Walsh RA, Price RL, Lim HW, Molkentin JD. Pathogenesis of dilated cardiomyopathy: molecular, structural, and population analyses in tropomodulin-overexpressing transgenic mice. The American Journal of Pathology. 155: 2101-13. PMID 10595939 DOI: 10.1016/S0002-9440(10)65528-9  0.357
1998 Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD. Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science (New York, N.Y.). 281: 1690-3. PMID 9733519 DOI: 10.1126/Science.281.5383.1690  0.391
1998 Sussman MA, Baqué S, Uhm CS, Daniels MP, Price RL, Simpson D, Terracio L, Kedes L. Altered expression of tropomodulin in cardiomyocytes disrupts the sarcomeric structure of myofibrils. Circulation Research. 82: 94-105. PMID 9440708 DOI: 10.1161/01.Res.82.1.94  0.557
1998 Sussman MA, Welch S, Cambon N, Klevitsky R, Hewett TE, Price R, Witt SA, Kimball TR. Myofibril degeneration caused by tropomodulin overexpression leads to dilated cardiomyopathy in juvenile mice. The Journal of Clinical Investigation. 101: 51-61. PMID 9421465 DOI: 10.1172/Jci1167  0.387
1997 Sussman MA, Hamm-Alvarez SF, Vilalta PM, Welch S, Kedes L. Involvement of phosphorylation in doxorubicin-mediated myofibril degeneration: An immunofluorescence microscopy analysis Circulation Research. 80: 52-61. PMID 8978322 DOI: 10.1161/01.Res.80.1.52  0.585
1996 Sussman MA, McAvoy JW, Rudisill M, Swanson B, Lyons GE, Kedes L, Blanks J. Lens tropomodulin: Developmental expression during differentiation Experimental Eye Research. 63: 223-232. PMID 8983980 DOI: 10.1006/Exer.1996.0111  0.55
1996 Sussman MA, Ito M, Daniels MP, Flucher B, Buranen S, Kedes L. Chicken skeletal muscle tropomodulin: novel localization and characterization. Cell and Tissue Research. 285: 287-96. PMID 8766165 DOI: 10.1007/S004410050646  0.512
1995 Ito M, Swanson B, Sussman MA, Kedes L, Lyons G. Cloning of tropomodulin cDNA and localization of gene transcripts during mouse embryogenesis Developmental Biology. 167: 317-328. PMID 7851652 DOI: 10.1006/Dbio.1995.1026  0.571
1995 Przyklenk K, Sussman MA, Simkhovich BZ, Kloner RA. Does ischemic preconditioning trigger translocation of protein kinase C in the canine model? Circulation. 92: 1546-57. PMID 7664439 DOI: 10.1161/01.Cir.92.6.1546  0.339
1994 Sussman MA, Sakhi S, Barrientos P, Ito M, Kedes L. Tropomodulin in rat cardiac muscle: Localization of protein is independent of messenger RNA distribution during myofibrillar development Circulation Research. 75: 221-232. PMID 8033336 DOI: 10.1161/01.Res.75.2.221  0.541
1994 Sussman MA, Sakhi S, Tocco G, Najm I, Baudry M, Kedes L, Schreiber SS. Neural tropomodulin: developmental expression and effect of seizure activity. Brain Research. Developmental Brain Research. 80: 45-53. PMID 7955359 DOI: 10.1016/0165-3806(94)90088-4  0.515
1993 Sussman MA, Bilak M, Kedes L, Engel WK, Askanas V. Tropomodulin is highly concentrated at the postsynaptic domain of human and rat neuromuscular junctions. Experimental Cell Research. 209: 388-91. PMID 8262158 DOI: 10.1006/Excr.1993.1325  0.508
1990 Shubin RA, Sussman MA, Fleming JO, Stohlman SA. Relapsing encephalomyelitis following transfer of partial immunity to JHM virus. Microbial Pathogenesis. 8: 305-14. PMID 1977071 DOI: 10.1016/0882-4010(90)90089-9  0.526
1989 Sussman MA, Shubin RA, Kyuwa S, Stohlman SA. T-cell-mediated clearance of mouse hepatitis virus strain JHM from the central nervous system. Journal of Virology. 63: 3051-6. PMID 2542613 DOI: 10.1128/Jvi.63.7.3051-3056.1989  0.521
1989 Fleming JO, Shubin RA, Sussman MA, Casteel N, Stohlman SA. Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis. Virology. 168: 162-7. PMID 2535900 DOI: 10.1016/0042-6822(89)90415-7  0.508
1988 Stohlman SA, Sussman MA, Matsushima GK, Shubin RA, Erlich SS. Delayed-type hypersensitivity response in the central nervous system during JHM virus infection requires viral specificity for protection. Journal of Neuroimmunology. 19: 255-68. PMID 2842378 DOI: 10.1016/0165-5728(88)90007-0  0.538
1987 Sussman MA, Fleming JO, Allen H, Stohlman SA. Immune mediated clearance of JHM virus from the central nervous system. Advances in Experimental Medicine and Biology. 218: 399-410. PMID 2829552 DOI: 10.1007/978-1-4684-1280-2_49  0.534
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