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Cullen L. Schmid - Publications

Affiliations: 
2011 Ohio State University, Columbus, Columbus, OH 
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Acevedo-Canabal A, Grim TW, Schmid CL, McFague N, Stahl EL, Kennedy NM, Bannister TD, Bohn LM. Hyperactivity in Mice Induced by Opioid Agonists with Partial Intrinsic Efficacy and Biased Agonism Administered Alone and in Combination with Morphine. Biomolecules. 13. PMID 37371516 DOI: 10.3390/biom13060935  0.747
2022 Stahl E, Schmid CL, Acevedo-Canabal A, Read C, Grim T, Kennedy NM, Bannister TD, Bohn LM. Irreversible and noncompetitive mu opioid receptor agonists. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35552911 DOI: 10.1096/fasebj.2022.36.S1.R1962  0.783
2021 Stahl EL, Schmid CL, Acevedo-Canabal A, Read C, Grim TW, Kennedy NM, Bannister TD, Bohn LM. G protein signaling-biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34819362 DOI: 10.1073/pnas.2102178118  0.781
2020 Pantouli F, Grim TW, Schmid CL, Acevedo-Canabal A, Kennedy NM, Cameron MD, Bannister TD, Bohn LM. Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain. Neuropharmacology. 108439. PMID 33345829 DOI: 10.1016/j.neuropharm.2020.108439  0.679
2019 Grim TW, Schmid CL, Stahl EL, Pantouli F, Ho JH, Acevedo-Canabal A, Kennedy NM, Cameron MD, Bannister TD, Bohn LM. A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31443104 DOI: 10.1038/S41386-019-0491-8  0.768
2018 Kennedy NM, Schmid CL, Ross NC, Lovell KM, Yue Z, Chen YT, Cameron MD, Bohn LM, Bannister TD. Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias. Journal of Medicinal Chemistry. PMID 30199635 DOI: 10.1021/Acs.Jmedchem.8B01136  0.833
2018 Grim TW, Park SJ, Schmid CL, Laprairie RB, Cameron M, Bohn LM. The effect of quinine in two bottle choice procedures in C57BL6 mice: Opioid preference, somatic withdrawal, and pharmacokinetic outcomes. Drug and Alcohol Dependence. 191: 195-202. PMID 30138791 DOI: 10.1016/J.Drugalcdep.2018.05.034  0.714
2018 Ho JH, Stahl EL, Schmid CL, Scarry SM, Aubé J, Bohn LM. G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons. Science Signaling. 11. PMID 30087177 DOI: 10.1126/Scisignal.Aar4309  0.747
2017 Roach JJ, Sasano Y, Schmid CL, Zaidi S, Katritch V, Stevens RC, Bohn LM, Shenvi RA. Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist. Acs Central Science. 3: 1329-1336. PMID 29296674 DOI: 10.1021/Acscentsci.7B00488  0.67
2017 Schmid CL, Kennedy NM, Ross NC, Lovell KM, Yue Z, Morgenweck J, Cameron MD, Bannister TD, Bohn LM. Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics. Cell. 171: 1165-1175.e13. PMID 29149605 DOI: 10.1016/J.Cell.2017.10.035  0.83
2017 Mason JW, Schmid CL, Bohn LM, Roush WR. Stolonidiol: Synthesis, Target Identification, and Mechanism for Choline Acetyltransferase Activation. Journal of the American Chemical Society. PMID 28414442 DOI: 10.1021/Jacs.7B01083  0.589
2016 Brust TF, Morgenweck J, Kim SA, Rose JH, Locke JL, Schmid CL, Zhou L, Stahl EL, Cameron MD, Scarry SM, Aubé J, Jones SR, Martin TJ, Bohn LM. Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria. Science Signaling. 9: ra117. PMID 27899527 DOI: 10.1126/Scisignal.Aai8441  0.777
2015 Green JA, Schmid CL, Bley E, Monsma PC, Brown A, Bohn LM, Mykytyn K. Recruitment of β-arrestin into Neuronal Cilia Modulates Somatostatin Receptor Subtype 3 Ciliary Localization. Molecular and Cellular Biology. PMID 26503786 DOI: 10.1128/Mcb.00765-15  0.642
2014 Schmid CL, Streicher JM, Meltzer HY, Bohn LM. Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1902-13. PMID 24531562 DOI: 10.1038/Npp.2014.38  0.729
2013 Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM. Development of functionally selective, small molecule agonists at kappa opioid receptors. The Journal of Biological Chemistry. 288: 36703-16. PMID 24187130 DOI: 10.1074/Jbc.M113.504381  0.828
2013 Schmid CL, Streicher JM, Groer CE, Munro TA, Zhou L, Bohn LM. Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons. The Journal of Biological Chemistry. 288: 22387-98. PMID 23775075 DOI: 10.1074/Jbc.M113.476234  0.757
2012 Nguyen PT, Schmid CL, Raehal KM, Selley DE, Bohn LM, Sim-Selley LJ. β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner. Biological Psychiatry. 71: 714-24. PMID 22264443 DOI: 10.1016/J.Biopsych.2011.11.027  0.781
2011 Raehal KM, Schmid CL, Groer CE, Bohn LM. Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance. Pharmacological Reviews. 63: 1001-19. PMID 21873412 DOI: 10.1124/Pr.111.004598  0.822
2011 Groer CE, Schmid CL, Jaeger AM, Bohn LM. Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation. The Journal of Biological Chemistry. 286: 31731-41. PMID 21757712 DOI: 10.1074/Jbc.M111.248310  0.778
2010 Schmid CL, Bohn LM. Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13513-24. PMID 20926677 DOI: 10.1523/Jneurosci.1665-10.2010  0.636
2010 Bohn LM, Schmid CL. Serotonin receptor signaling and regulation via β-arrestins. Critical Reviews in Biochemistry and Molecular Biology. 45: 555-66. PMID 20925600 DOI: 10.3109/10409238.2010.516741  0.729
2010 Fei G, Raehal K, Liu S, Qu MH, Sun X, Wang GD, Wang XY, Xia Y, Schmid CL, Bohn LM, Wood JD. Lubiprostone reverses the inhibitory action of morphine on intestinal secretion in guinea pig and mouse. The Journal of Pharmacology and Experimental Therapeutics. 334: 333-40. PMID 20406855 DOI: 10.1124/Jpet.110.166116  0.78
2009 Raehal KM, Schmid CL, Medvedev IO, Gainetdinov RR, Premont RT, Bohn LM. Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6. Drug and Alcohol Dependence. 104: 187-96. PMID 19497686 DOI: 10.1016/J.Drugalcdep.2009.04.011  0.818
2009 Schmid CL, Bohn LM. Physiological and pharmacological implications of beta-arrestin regulation. Pharmacology & Therapeutics. 121: 285-93. PMID 19100766 DOI: 10.1016/J.Pharmthera.2008.11.005  0.716
2008 Schmid CL, Raehal KM, Bohn LM. Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 1079-84. PMID 18195357 DOI: 10.1073/Pnas.0708862105  0.77
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