Dionicio R. Siegel, Ph.D. - Publications

Affiliations: 
2003 Harvard University, Cambridge, MA, United States 
Area:
synthesis of natural products

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Camelio AM, Johnson TC, Siegel D. Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products. Journal of the American Chemical Society. 137: 11864-7. PMID 26331410 DOI: 10.1021/jacs.5b06261  1
2015 Cho J, Rho O, Junco JJ, Carbajal S, Siegel D, Slaga TJ, DiGiovanni J. Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-tetradecanoylphorbol-13-acetate. Cancer Prevention Research (Philadelphia, Pa.). PMID 26100520 DOI: 10.1158/1940-6207.CAPR-15-0098  1
2015 Chin MR, Zlotkowski K, Han M, Patel S, Eliasen AM, Axelrod A, Siegel D. Expedited access to vinaxanthone and chemically edited derivatives possessing neuronal regenerative effects through ynone coupling reactions. Acs Chemical Neuroscience. 6: 542-50. PMID 25615693 DOI: 10.1021/cn500237z  1
2015 Eliasen AM, Christy M, Claussen KR, Besandre R, Thedford RP, Siegel D. Dearomatization Reactions Using Phthaloyl Peroxide Organic Letters. 17: 4420-4423. DOI: 10.1021/acs.orglett.5b02008  1
2015 Camelio AM, Liang Y, Eliasen AM, Johnson TC, Yuan C, Schuppe AW, Houk KN, Siegel D. Computational and Experimental Studies of Phthaloyl Peroxide-Mediated Hydroxylation of Arenes Yield a More Reactive Derivative, 4,5-Dichlorophthaloyl Peroxide Journal of Organic Chemistry. 80: 8084-8095. DOI: 10.1021/acs.joc.5b01079  1
2015 Nelson AT, Camelio AM, Claussen KR, Cho J, Tremmel L, DiGiovanni J, Siegel D. Synthesis of oxygenated oleanolic and ursolic acid derivatives with anti-inflammatory properties Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.07.029  1
2014 Yuan C, Eliasen AM, Camelio AM, Siegel D. Preparation of phenols by phthaloyl peroxide-mediated oxidation of arenes Nature Protocols. 9: 2624-2629. PMID 25321407 DOI: 10.1038/nprot.2014.175  1
2014 Eliasen AM, Thedford RP, Claussen KR, Yuan C, Siegel D. A protocol to generate phthaloyl peroxide in flow for the hydroxylation of arenes Organic Letters. 16: 3628-3631. PMID 24988535 DOI: 10.1021/ol501497y  1
2014 Johnson T, Siegel D. Complanadine A, a selective agonist for the Mas-related G protein-coupled receptor X2 Bioorganic and Medicinal Chemistry Letters. 24: 3512-3515. PMID 24930830 DOI: 10.1016/j.bmcl.2014.05.060  1
2013 Zlotkowski K, Eliasen AM, Mitra A, Siegel D. Small-molecule mechanism of action studies in Caenorhabditis elegans. Chembiochem : a European Journal of Chemical Biology. 14: 2338-44. PMID 24123757 DOI: 10.1002/cbic.201300399  1
2013 Yuan C, Liang Y, Hernandez T, Berriochoa A, Houk KN, Siegel D. Metal-free oxidation of aromatic carbon-hydrogen bonds through a reverse-rebound mechanism. Nature. 499: 192-6. PMID 23846658 DOI: 10.1038/nature12284  1
2013 Yuan C, Chang CT, Siegel D. Syntheses of (+)-complanadine A and lycodine derivatives by regioselective [2 + 2 + 2] cycloadditions. The Journal of Organic Chemistry. 78: 5647-68. PMID 23635039 DOI: 10.1021/jo400695c  1
2013 Zlotkowski K, Pierce-Shimomura J, Siegel D. Small-molecule-mediated axonal branching in Caenorhabditis elegans. Chembiochem : a European Journal of Chemical Biology. 14: 307-10. PMID 23362121 DOI: 10.1002/cbic.201200712  1
2013 Axelrod A, Eliasen AM, Chin MR, Zlotkowski K, Siegel D. Syntheses of xanthofulvin and vinaxanthone, natural products enabling spinal cord regeneration Angewandte Chemie - International Edition. 52: 3421-3424. PMID 23086682 DOI: 10.1002/anie.201205837  1
2012 Cheng X, Harzdorf N, Khaing Z, Kang D, Camelio AM, Shaw T, Schmidt CE, Siegel D. Neuronal growth promoting sesquiterpene-neolignans; syntheses and biological studies. Organic & Biomolecular Chemistry. 10: 383-93. PMID 22083452 DOI: 10.1039/c1ob06363d  1
2012 Barton T, Siegel D. Investigation of an acrylate lynchpin approach toward the synthesis of stolonidiol Synthesis (Germany). 44: 2770-2778. DOI: 10.1055/s-0032-1316589  1
2011 Piasecki SK, Taylor CA, Detelich JF, Liu J, Zheng J, Komsoukaniants A, Siegel DR, Keatinge-Clay AT. Employing modular polyketide synthase ketoreductases as biocatalysts in the preparative chemoenzymatic syntheses of diketide chiral building blocks. Chemistry & Biology. 18: 1331-40. PMID 22035802 DOI: 10.1016/j.chembiol.2011.07.021  1
2011 Vidal-Gadea A, Topper S, Young L, Crisp A, Kressin L, Elbel E, Maples T, Brauner M, Erbguth K, Axelrod A, Gottschalk A, Siegel D, Pierce-Shimomura JT. Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin. Proceedings of the National Academy of Sciences of the United States of America. 108: 17504-9. PMID 21969584 DOI: 10.1073/pnas.1108673108  1
2011 Khaing Z, Kang D, Camelio AM, Schmidt CE, Siegel D. Hippocampal and cortical neuronal growth mediated by the small molecule natural product clovanemagnolol. Bioorganic & Medicinal Chemistry Letters. 21: 4808-12. PMID 21757342 DOI: 10.1016/j.bmcl.2011.06.054  1
2011 Zhang M, Cho EJ, Burstein G, Siegel D, Zhang Y. Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor Acs Chemical Biology. 6: 511-519. PMID 21348431 DOI: 10.1021/cb100357t  1
2011 Camelio AM, Barton T, Guo F, Shaw T, Siegel D. Hydroxyl-directed cyclizations of 1,6-enynes Organic Letters. 13: 1517-1519. PMID 21314167 DOI: 10.1021/ol200157x  1
2011 Yuan C, Axelrod A, Varela M, Danysh L, Siegel D. Synthesis and reaction of phthaloyl peroxide derivatives, potential organocatalysts for the stereospecific dihydroxylation of alkenes Tetrahedron Letters. 52: 2540-2542. DOI: 10.1016/j.tetlet.2011.03.005  1
2010 Yuan C, Chang CT, Axelrod A, Siegel D. Synthesis of (+)-complanadine A, an inducer of neurotrophic factor excretion. Journal of the American Chemical Society. 132: 5924-5. PMID 20387896 DOI: 10.1021/ja101956x  1
2010 Cheng X, Harzdorf NL, Shaw T, Siegel D. Biomimetic syntheses of the neurotrophic natural products caryolanemagnolol and clovanemagnolol Organic Letters. 12: 1304-1307. PMID 20158263 DOI: 10.1021/ol100214X  1
2010 Tsukano C, Siegel DR, Danishefsky SJ. Total syntheses of polycyclic polyp renylated acylphloroglucinols Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 68: 592-600.  1
2008 Sun C, Wang Q, Brubaker JD, Wright PM, Lerner CD, Noson K, Charest M, Siegel DR, Wang YM, Myers AG. A robust platform for the synthesis of new tetracycline antibiotics. Journal of the American Chemical Society. 130: 17913-27. PMID 19053822 DOI: 10.1021/ja806629e  1
2007 Tsukano C, Siegel DR, Danishefsky SJ. Differentiation of nonconventional "carbanions"-the total synthesis of nemorosone and clusianone. Angewandte Chemie (International Ed. in English). 46: 8840-4. PMID 17935090 DOI: 10.1002/anie.200703886  1
2006 Liu H, Siegel DR, Danishefsky SJ. Studies directed toward the synthesis of terreulactone A: rapid construction of the A, B, C rings. Organic Letters. 8: 423-5. PMID 16435850 DOI: 10.1021/ol052618p  1
2006 Siegel DR, Danishefsky SJ. Total synthesis of garsubellin A. Journal of the American Chemical Society. 128: 1048-9. PMID 16433500 DOI: 10.1021/ja057418n  1
2005 Charest MG, Siegel DR, Myers AG. Synthesis of (-)-tetracycline. Journal of the American Chemical Society. 127: 8292-3. PMID 15941256 DOI: 10.1021/ja052151d  1
2005 Charest MG, Lerner CD, Brubaker JD, Siegel DR, Myers AG. A convergent enantioselective route to structurally diverse 6-deoxytetracycline antibiotics. Science (New York, N.Y.). 308: 395-8. PMID 15831754 DOI: 10.1126/science.1109755  1
2001 Myers AG, Siegel DR, Buzard DJ, Charest MG. Synthesis of a broad array of highly functionalized, enantiomerically pure cyclohexanecarboxylic acid derivatives by microbial dihydroxylation of benzoic acid and subsequent oxidative and rearrangement reactions. Organic Letters. 3: 2923-6. PMID 11529791 DOI: 10.1021/ol010151m  1
1999 Alper PB, Meyers C, Lerchner A, Siegel DR, Carreira EM. Facile, Novel Methodology for the Synthesis of Spiro Angewandte Chemie (International Ed. in English). 38: 3186-3189. PMID 10556897 DOI: 10.1002/(SICI)1521-3773(19991102)38:21<3186::AID-ANIE3186>3.0.CO;2-E  1
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