| Year |
Citation |
Score |
| 2024 |
Ireland KA, Kayrouz CM, Abbott ML, Seyedsayamdost MR, Davis KM. Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure (London, England : 1993). PMID 39216472 DOI: 10.1016/j.str.2024.08.006 |
0.813 |
|
| 2024 |
Kayrouz CM, Ireland KA, Ying VY, Davis KM, Seyedsayamdost MR. Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution. Nature Chemistry. PMID 39143299 DOI: 10.1038/s41557-024-01600-2 |
0.815 |
|
| 2024 |
Nguy AKL, Martinie RJ, Cai A, Seyedsayamdost MR. Detection of a Kinetically Competent Compound-I Intermediate in the Vancomycin Biosynthetic Enzyme OxyB. Journal of the American Chemical Society. PMID 38989876 DOI: 10.1021/jacs.4c03102 |
0.772 |
|
| 2024 |
Kayrouz CM, Seyedsayamdost MR. Enzymatic strategies for selenium incorporation into biological molecules. Current Opinion in Chemical Biology. 81: 102495. PMID 38954947 DOI: 10.1016/j.cbpa.2024.102495 |
0.796 |
|
| 2024 |
Kayrouz CM, Ireland KA, Ying V, Davis KM, Seyedsayamdost MR. Ovoselenol, a Selenium-containing Antioxidant Derived from Convergent Evolution. Biorxiv : the Preprint Server For Biology. PMID 38645211 DOI: 10.1101/2024.04.10.588772 |
0.815 |
|
| 2024 |
Chioti VT, Clark KA, Ganley JG, Han EJ, Seyedsayamdost MR. N-Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster. Journal of the American Chemical Society. PMID 38452252 DOI: 10.1021/jacs.3c11740 |
0.81 |
|
| 2024 |
Johnson BA, Clark KA, Bushin LB, Spolar CN, Seyedsayamdost MR. Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis. Journal of the American Chemical Society. PMID 38316431 DOI: 10.1021/jacs.3c10824 |
0.832 |
|
| 2023 |
Ireland KA, Kayrouz CM, Huang J, Seyedsayamdost MR, Davis KM. Structural Characterization and Ligand-Induced Conformational Changes of SenB, a Se-Glycosyltransferase Involved in Selenoneine Biosynthesis. Biochemistry. PMID 37966244 DOI: 10.1021/acs.biochem.3c00452 |
0.801 |
|
| 2023 |
Seyedsayamdost MR, Clardy J. Discovering functional small molecules in the gut microbiome. Current Opinion in Chemical Biology. 75: 102309. PMID 37163788 DOI: 10.1016/j.cbpa.2023.102309 |
0.408 |
|
| 2022 |
Clark KA, Covington BC, Seyedsayamdost MR. Biosynthesis-guided discovery reveals enteropeptins as alternative sactipeptides containing N-methylornithine. Nature Chemistry. PMID 36316408 DOI: 10.1038/s41557-022-01063-3 |
0.816 |
|
| 2022 |
Han EJ, Lee SR, Hoshino S, Seyedsayamdost MR. Targeted Discovery of Cryptic Metabolites with Antiproliferative Activity. Acs Chemical Biology. PMID 36228140 DOI: 10.1021/acschembio.2c00588 |
0.321 |
|
| 2022 |
Clark KA, Seyedsayamdost MR. Bioinformatic Atlas of Radical SAM Enzyme-Modified RiPP Natural Products Reveals an Isoleucine-Tryptophan Crosslink. Journal of the American Chemical Society. PMID 36128669 DOI: 10.1021/jacs.2c06497 |
0.822 |
|
| 2022 |
Kayrouz CM, Huang J, Hauser N, Seyedsayamdost MR. Biosynthesis of selenium-containing small molecules in diverse microorganisms. Nature. PMID 36071162 DOI: 10.1038/s41586-022-05174-2 |
0.829 |
|
| 2022 |
Clark KA, Bushin LB, Seyedsayamdost MR. RaS-RiPPs in Streptococci and the Human Microbiome. Acs Bio & Med Chem Au. 2: 328-339. PMID 35996476 DOI: 10.1021/acsbiomedchemau.2c00004 |
0.803 |
|
| 2022 |
Covington BC, Seyedsayamdost MR. Vitamin B3 Triggers Biosynthesis of Secondary Metabolite Dormancy Signals in . Journal of the American Chemical Society. PMID 35969232 DOI: 10.1021/jacs.2c05790 |
0.386 |
|
| 2022 |
Bushin LB, Covington BC, Clark KA, Caruso A, Seyedsayamdost MR. Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nature Chemical Biology. PMID 35953547 DOI: 10.1038/s41589-022-01090-8 |
0.813 |
|
| 2022 |
Li Y, Lee SR, Han EJ, Seyedsayamdost MR. Momomycin, an Antiproliferative Cryptic Metabolite from the Oxytetracycline Producer Streptomyces rimosus. Angewandte Chemie (International Ed. in English). e202208573. PMID 35903822 DOI: 10.1002/anie.202208573 |
0.332 |
|
| 2022 |
Zhang Y, Gallant É, Park JD, Seyedsayamdost MR. The Small-Molecule Language of Dynamic Microbial Interactions. Annual Review of Microbiology. PMID 35679616 DOI: 10.1146/annurev-micro-042722-091052 |
0.771 |
|
| 2021 |
Covington BC, Seyedsayamdost MR. Guidelines for metabolomics-guided transposon mutagenesis for microbial natural product discovery. Methods in Enzymology. 665: 305-323. PMID 35379440 DOI: 10.1016/bs.mie.2021.11.020 |
0.302 |
|
| 2021 |
Park JD, Li Y, Moon K, Han EJ, Lee SR, Seyedsayamdost MR. Structural Elucidation of Cryptic Algaecides in Marine Algal-Bacterial Symbioses by NMR Spectroscopy and MicroED. Angewandte Chemie (International Ed. in English). PMID 34852184 DOI: 10.1002/anie.202114022 |
0.781 |
|
| 2021 |
Wang R, Gallant É, Wilson MZ, Wu Y, Li A, Gitai Z, Seyedsayamdost MR. Algal p-coumaric acid induces oxidative stress and siderophore biosynthesis in the bacterial symbiont Phaeobacter inhibens. Cell Chemical Biology. PMID 34437838 DOI: 10.1016/j.chembiol.2021.08.002 |
0.781 |
|
| 2021 |
Caruso A, Seyedsayamdost MR. Radical SAM Enzyme QmpB Installs Two 9-Membered Ring Sactionine Macrocycles during Biogenesis of a Ribosomal Peptide Natural Product. The Journal of Organic Chemistry. PMID 34351169 DOI: 10.1021/acs.joc.1c01507 |
0.811 |
|
| 2021 |
Balo AR, Caruso A, Tao L, Tantillo DJ, Seyedsayamdost MR, Britt RD. Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34001621 DOI: 10.1073/pnas.2101571118 |
0.8 |
|
| 2021 |
Covington BC, Xu F, Seyedsayamdost MR. A Natural Product Chemist's Guide to Unlocking Silent Biosynthetic Gene Clusters. Annual Review of Biochemistry. PMID 33848426 DOI: 10.1146/annurev-biochem-081420-102432 |
0.337 |
|
| 2021 |
Rued BE, Covington BC, Bushin LB, Szewczyk G, Laczkovich I, Seyedsayamdost MR, Federle MJ. Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound. Mbio. 12. PMID 33727351 DOI: 10.1128/mBio.02688-20 |
0.326 |
|
| 2020 |
Forneris CC, Nguy AKL, Seyedsayamdost MR. Mapping and Exploiting the Promiscuity of OxyB toward the Biocatalytic Production of Vancomycin Aglycone Variants. Acs Catalysis. 10: 9287-9298. PMID 34422446 DOI: 10.1021/acscatal.0c01719 |
0.316 |
|
| 2020 |
Vrla GD, Esposito M, Zhang C, Kang Y, Seyedsayamdost MR, Gitai Z. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. Plos Pathogens. 16: e1008867. PMID 32925969 DOI: 10.1371/Journal.Ppat.1008867 |
0.309 |
|
| 2020 |
Bushin LB, Covington BC, Rued BE, Federle MJ, Seyedsayamdost MR. Discovery and Biosynthesis of Streptosactin, a Sactipeptide with an Alternative Topology Encoded by Commensal Bacteria in the Human Microbiome. Journal of the American Chemical Society. PMID 32845143 DOI: 10.1021/Jacs.0C05546 |
0.529 |
|
| 2020 |
Yoshimura A, Covington BC, Gallant E, Zhang C, Li A, Seyedsayamdost MR. Unlocking Cryptic Metabolites with Mass Spectrometry-Guided Transposon Mutant Selection. Acs Chemical Biology. PMID 32808751 DOI: 10.1021/Acschembio.0C00558 |
0.687 |
|
| 2020 |
Seyedsayamdost MR, Stallforth P. Special Issue in Honor of Professor Jon Clardy. Journal of Natural Products. 83: 565-568. PMID 32216264 DOI: 10.1021/Acs.Jnatprod.0C00199 |
0.595 |
|
| 2020 |
Zhang C, Seyedsayamdost MR. CanE, an Iron/2-Oxoglutarate-dependent Lasso Peptide Hydroxylase from . Acs Chemical Biology. PMID 32191027 DOI: 10.1021/Acschembio.0C00109 |
0.418 |
|
| 2020 |
Greenberg EP, Chandler JR, Seyedsayamdost MR. The Chemistry and Biology of Bactobolin: A 10-Year Collaboration with Natural Product Chemist Extraordinaire Jon Clardy. Journal of Natural Products. PMID 32105069 DOI: 10.1021/Acs.Jnatprod.9B01237 |
0.423 |
|
| 2020 |
Li A, Mao D, Yoshimura A, Rosen PC, Martin WL, Gallant É, Wühr M, Seyedsayamdost MR. Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis. Mbio. 11. PMID 32098820 DOI: 10.1128/Mbio.03210-19 |
0.69 |
|
| 2020 |
Mao D, Yoshimura A, Wang R, Seyedsayamdost MR. Reporter-Guided Transposon Mutant Selection for Activation of Silent Gene Clusters in Burkholderia thailandensis. Chembiochem : a European Journal of Chemical Biology. PMID 31984619 DOI: 10.1002/Cbic.201900748 |
0.8 |
|
| 2020 |
Forneris CC, Nguy AKL, Seyedsayamdost MR. Mapping and Exploiting the Promiscuity of OxyB toward the Biocatalytic Production of Vancomycin Aglycone Variants Acs Catalysis. 10: 9287-9298. DOI: 10.1021/Acscatal.0C01719 |
0.314 |
|
| 2019 |
Park JD, Moon K, Miller C, Rose J, Xu F, Ebmeier CC, Jabcobsen JR, Mao D, Old WM, DeShazer D, Seyedsayamdost MR. Thailandenes, cryptic polyene natural products isolated from using phenotype-guided transposon mutagenesis. Acs Chemical Biology. PMID 31816232 DOI: 10.1021/Acschembio.9B00883 |
0.799 |
|
| 2019 |
Caruso A, Martinie RJ, Bushin LB, Seyedsayamdost MR. Macrocyclization via an Arginine-Tyrosine Crosslink Broadens the Reaction Scope of Radical -Adenosylmethionine Enzymes. Journal of the American Chemical Society. PMID 31596076 DOI: 10.1021/Jacs.9B09210 |
0.814 |
|
| 2019 |
Isley NA, Endo Y, Wu ZC, Covington BC, Bushin LB, Seyedsayamdost MR, Boger DL. Total Synthesis and Stereochemical Assignment of Streptide. Journal of the American Chemical Society. PMID 31577142 DOI: 10.1021/Jacs.9B09067 |
0.407 |
|
| 2019 |
Clark KA, Bushin LB, Seyedsayamdost MR. Aliphatic Ether Bond Formation Expands the Scope of Radical SAM Enzymes in Natural Product Biosynthesis. Journal of the American Chemical Society. PMID 31246011 DOI: 10.1021/Jacs.9B05151 |
0.835 |
|
| 2019 |
Okada BK, Li A, Seyedsayamdost MR. Identification of the Hypertension Drug Guanfacine as an Anti-virulence Agent in Pseudomonas aeruginosa. Chembiochem : a European Journal of Chemical Biology. PMID 30927315 DOI: 10.1002/Cbic.201900129 |
0.369 |
|
| 2019 |
Moon K, Xu F, Seyedsayamdost MR. Cebulantin, a Cryptic Lanthipeptide Antibiotic Uncovered via Bioactivity-Coupled HiTES. Angewandte Chemie (International Ed. in English). PMID 30843641 DOI: 10.1002/Anie.201901342 |
0.765 |
|
| 2019 |
Moon K, Xu F, Zhang C, Seyedsayamdost MR. Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria. Acs Chemical Biology. PMID 30830740 DOI: 10.1021/Acschembio.9B00049 |
0.768 |
|
| 2019 |
Seyedsayamdost MR. Toward a global picture of bacterial secondary metabolism. Journal of Industrial Microbiology & Biotechnology. PMID 30684124 DOI: 10.1007/S10295-019-02136-Y |
0.364 |
|
| 2019 |
Xu F, Wu Y, Zhang C, Davis KM, Moon K, Bushin LB, Seyedsayamdost MR. A genetics-free method for high-throughput discovery of cryptic microbial metabolites. Nature Chemical Biology. PMID 30617293 DOI: 10.1038/S41589-018-0193-2 |
0.75 |
|
| 2018 |
Stubbe J, Seyedsayamdost MR. Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer. Biochemistry. PMID 30586288 DOI: 10.1021/Acs.Biochem.8B01238 |
0.497 |
|
| 2018 |
Caruso A, Bushin LB, Clark KA, Martinie RJ, Seyedsayamdost MR. A Radical Approach to Enzymatic β-Thioether Bond Formation. Journal of the American Chemical Society. PMID 30521328 DOI: 10.1021/Jacs.8B11060 |
0.801 |
|
| 2018 |
Bushin LB, Clark KA, Pelczer I, Seyedsayamdost MR. Charting an Unexplored Streptococcal Biosynthetic Landscape Reveals a Unique Peptide Cyclization Motif. Journal of the American Chemical Society. PMID 30398325 DOI: 10.1021/Jacs.8B10266 |
0.83 |
|
| 2018 |
Forneris CC, Ozturk S, Sorensen EJ, Seyedsayamdost MR. Installation of Multiple Aryl Ether Crosslinks onto Non-Native Substrate Peptides by the Vancomycin OxyB. Tetrahedron. 74: 3231-3237. PMID 30386000 DOI: 10.1016/J.Tet.2018.04.028 |
0.417 |
|
| 2018 |
McRose DL, Seyedsayamdost MR, Morel FMM. Multiple siderophores: bug or feature? Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 30264174 DOI: 10.1007/S00775-018-1617-X |
0.38 |
|
| 2018 |
Bushin LB, Seyedsayamdost MR. Guidelines for Determining the Structures of Radical SAM Enzyme-Catalyzed Modifications in the Biosynthesis of RiPP Natural Products. Methods in Enzymology. 606: 439-460. PMID 30097102 DOI: 10.1016/Bs.Mie.2018.04.016 |
0.427 |
|
| 2018 |
Wu Y, Seyedsayamdost MR. The Polyene Natural Product Thailandamide A Inhibits Fatty Acid Biosynthesis in Gram-Positive and Gram-Negative Bacteria. Biochemistry. PMID 29975047 DOI: 10.1021/Acs.Biochem.8B00678 |
0.434 |
|
| 2018 |
McRose DL, Baars O, Seyedsayamdost MR, Morel FMM. Quorum sensing and iron regulate a two-for-one siderophore gene cluster in . Proceedings of the National Academy of Sciences of the United States of America. PMID 29954861 DOI: 10.1073/Pnas.1805791115 |
0.338 |
|
| 2018 |
Mao D, Okada BK, Wu Y, Xu F, Seyedsayamdost MR. Recent advances in activating silent biosynthetic gene clusters in bacteria. Current Opinion in Microbiology. 45: 156-163. PMID 29883774 DOI: 10.1016/J.Mib.2018.05.001 |
0.447 |
|
| 2018 |
Ozturk S, Forneris CC, Nguy AKL, Sorensen EJ, Seyedsayamdost MR. Modulating OxyB-Catalyzed Cross-Coupling Reactions in Vancomycin Biosynthesis by Incorporation of Diverse D-Tyr Analogs. The Journal of Organic Chemistry. PMID 29806454 DOI: 10.1021/Acs.Joc.8B00916 |
0.396 |
|
| 2018 |
Klaus JR, Deay J, Neuenswander B, Hursh W, Gao Z, Bouddhara T, Williams TD, Douglas J, Monize K, Martins P, Majerczyk C, Seyedsayamdost MR, Peterson BR, Rivera M, Chandler JR. Malleilactone is a virulence factor regulated by antibiotics and quorum sensing. Journal of Bacteriology. PMID 29735757 DOI: 10.1128/Jb.00008-18 |
0.383 |
|
| 2018 |
Forneris CC, Seyedsayamdost MR. In Vitro Reconstitution of OxyC Activity Enables Total Chemoenzymatic Syntheses of Vancomycin Aglycone Variants. Angewandte Chemie (International Ed. in English). 57: 8048-8052. PMID 29697176 DOI: 10.1002/Anie.201802856 |
0.438 |
|
| 2018 |
Schramma KR, Forneris CC, Caruso A, Seyedsayamdost MR. Mechanistic Investigations of Lysine-Tryptophan Cross-Link Formation Catalyzed by Streptococcal Radical S-Adenosylmethionine Enzymes. Biochemistry. 57: 461-468. PMID 29320164 DOI: 10.1021/Acs.Biochem.7B01147 |
0.804 |
|
| 2017 |
Wu Y, Seyedsayamdost MR. Synergy and Target Promiscuity Drive Structural Divergence in Bacterial Alkylquinolone Biosynthesis. Cell Chemical Biology. PMID 29033316 DOI: 10.1016/J.Chembiol.2017.08.024 |
0.441 |
|
| 2017 |
Wang R, Seyedsayamdost MR. Roseochelin B, an Algaecidal Natural Product Synthesized by the Roseobacter Phaeobacter inhibens in Response to Algal Sinapic Acid. Organic Letters. PMID 28920692 DOI: 10.1021/Acs.Orglett.7B02424 |
0.781 |
|
| 2017 |
Davis KM, Schramma KR, Hansen WA, Bacik JP, Khare SD, Seyedsayamdost MR, Ando N. Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proceedings of the National Academy of Sciences of the United States of America. PMID 28893989 DOI: 10.1073/Pnas.1703663114 |
0.408 |
|
| 2017 |
Forneris CC, Ozturk S, Gibson MI, Sorensen EJ, Seyedsayamdost MR. In Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis. Acs Chemical Biology. PMID 28696669 DOI: 10.1021/Acschembio.7B00456 |
0.463 |
|
| 2017 |
Nazari B, Forneris CC, Gibson MI, Moon K, Schramma KR, Seyedsayamdost MR. Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to date and the kistamicin biosynthetic gene cluster. Medchemcomm. 8: 780-788. PMID 28626548 DOI: 10.1039/C6Md00637J |
0.763 |
|
| 2017 |
Xu F, Nazari B, Moon K, Bushin LB, Seyedsayamdost MR. Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens. Journal of the American Chemical Society. PMID 28590725 DOI: 10.1021/Jacs.7B02716 |
0.769 |
|
| 2017 |
Reece SY, Seyedsayamdost MR. Long-range proton-coupled electron transfer in the Escherichia coli class Ia ribonucleotide reductase. Essays in Biochemistry. 61: 281-292. PMID 28487404 DOI: 10.1042/Ebc20160072 |
0.361 |
|
| 2017 |
Mao D, Bushin LB, Moon K, Wu Y, Seyedsayamdost MR. Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264. Proceedings of the National Academy of Sciences of the United States of America. PMID 28320949 DOI: 10.1073/Pnas.1619529114 |
0.749 |
|
| 2017 |
Papenfort K, Silpe JE, Schramma KR, Cong JP, Seyedsayamdost MR, Bassler BL. A Vibrio cholerae autoinducer-receptor pair that controls biofilm formation. Nature Chemical Biology. PMID 28319101 DOI: 10.1038/Nchembio.2336 |
0.361 |
|
| 2017 |
Schramma KR, Seyedsayamdost MR. Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci. Acs Chemical Biology. 12: 922-927. PMID 28191919 DOI: 10.1021/Acschembio.6B01069 |
0.486 |
|
| 2017 |
Metelev M, Arseniev A, Bushin LB, Kuznedelov K, Artamonova TO, Kondratenko R, Khodorkovskii M, Seyedsayamdost MR, Severinov K. Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae. Acs Chemical Biology. 12: 814-824. PMID 28106375 DOI: 10.1021/Acschembio.6B01154 |
0.349 |
|
| 2017 |
Okada BK, Seyedsayamdost MR. Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small molecules. Fems Microbiology Reviews. 41: 19-33. PMID 27576366 DOI: 10.1093/Femsre/Fuw035 |
0.451 |
|
| 2016 |
Okada BK, Wu Y, Mao D, Bushin LB, Seyedsayamdost MR. Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis. Acs Chemical Biology. PMID 27367535 DOI: 10.1021/Acschembio.6B00447 |
0.435 |
|
| 2016 |
Wang R, Gallant É, Seyedsayamdost MR. Investigation of the Genetics and Biochemistry of Roseobacticide Production in the Roseobacter Clade Bacterium Phaeobacter inhibens. Mbio. 7. PMID 27006458 DOI: 10.1128/Mbio.02118-15 |
0.819 |
|
| 2016 |
Wilson MZ, Wang R, Gitai Z, Seyedsayamdost MR. Mode of action and resistance studies unveil new roles for tropodithietic acid as an anticancer agent and the γ-glutamyl cycle as a proton sink. Proceedings of the National Academy of Sciences of the United States of America. PMID 26802120 DOI: 10.1073/Pnas.1518034113 |
0.784 |
|
| 2015 |
Baars O, Zhang X, Morel FM, Seyedsayamdost MR. The Siderophore Metabolome of Azotobacter vinelandii. Applied and Environmental Microbiology. PMID 26452553 DOI: 10.1128/Aem.03160-15 |
0.411 |
|
| 2015 |
Truong TT, Seyedsayamdost M, Greenberg EP, Chandler JR. A Burkholderia thailandensis Acyl-Homoserine Lactone-Independent Orphan LuxR Homolog That Activates Production of the Cytotoxin Malleilactone. Journal of Bacteriology. 197: 3456-62. PMID 26283771 DOI: 10.1128/Jb.00425-15 |
0.383 |
|
| 2015 |
Schramma KR, Bushin LB, Seyedsayamdost MR. Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink. Nature Chemistry. 7: 431-7. PMID 25901822 DOI: 10.1038/Nchem.2237 |
0.445 |
|
| 2014 |
Seyedsayamdost MR, Wang R, Kolter R, Clardy J. Hybrid biosynthesis of roseobacticides from algal and bacterial precursor molecules. Journal of the American Chemical Society. 136: 15150-3. PMID 25295497 DOI: 10.1021/Ja508782Y |
0.786 |
|
| 2014 |
Seyedsayamdost MR. High-throughput platform for the discovery of elicitors of silent bacterial gene clusters. Proceedings of the National Academy of Sciences of the United States of America. 111: 7266-71. PMID 24808135 DOI: 10.1073/Pnas.1400019111 |
0.43 |
|
| 2014 |
Seyedsayamdost MR, Clardy J. Natural products and synthetic biology. Acs Synthetic Biology. 3: 745-7. PMID 24742095 DOI: 10.1021/Sb400025P |
0.478 |
|
| 2013 |
Wörsdörfer B, Conner DA, Yokoyama K, Livada J, Seyedsayamdost M, Jiang W, Silakov A, Stubbe J, Bollinger JM, Krebs C. Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer. Journal of the American Chemical Society. 135: 8585-93. PMID 23676140 DOI: 10.1021/Ja401342S |
0.749 |
|
| 2012 |
Chandler JR, Truong TT, Silva PM, Seyedsayamdost MR, Carr G, Radey M, Jacobs MA, Sims EH, Clardy J, Greenberg EP. Bactobolin resistance is conferred by mutations in the L2 ribosomal protein. Mbio. 3. PMID 23249812 DOI: 10.1128/Mbio.00499-12 |
0.46 |
|
| 2012 |
Seyedsayamdost MR, Traxler MF, Clardy J, Kolter R. Old meets new: using interspecies interactions to detect secondary metabolite production in actinomycetes. Methods in Enzymology. 517: 89-109. PMID 23084935 DOI: 10.1016/B978-0-12-404634-4.00005-X |
0.552 |
|
| 2012 |
Adler C, Corbalán NS, Seyedsayamdost MR, Pomares MF, de Cristóbal RE, Clardy J, Kolter R, Vincent PA. Catecholate siderophores protect bacteria from pyochelin toxicity. Plos One. 7: e46754. PMID 23071628 DOI: 10.1371/Journal.Pone.0046754 |
0.48 |
|
| 2012 |
Traxler MF, Seyedsayamdost MR, Clardy J, Kolter R. Interspecies modulation of bacterial development through iron competition and siderophore piracy. Molecular Microbiology. 86: 628-44. PMID 22931126 DOI: 10.1111/Mmi.12008 |
0.477 |
|
| 2012 |
Seyedsayamdost MR, Cleto S, Carr G, Vlamakis H, João Vieira M, Kolter R, Clardy J. Mixing and matching siderophore clusters: structure and biosynthesis of serratiochelins from Serratia sp. V4. Journal of the American Chemical Society. 134: 13550-3. PMID 22830960 DOI: 10.1021/Ja304941D |
0.548 |
|
| 2011 |
Fernandes N, Case RJ, Longford SR, Seyedsayamdost MR, Steinberg PD, Kjelleberg S, Thomas T. Genomes and virulence factors of novel bacterial pathogens causing bleaching disease in the marine red alga Delisea pulchra. Plos One. 6: e27387. PMID 22162749 DOI: 10.1371/Journal.Pone.0027387 |
0.33 |
|
| 2011 |
Seyedsayamdost MR, Carr G, Kolter R, Clardy J. Roseobacticides: small molecule modulators of an algal-bacterial symbiosis. Journal of the American Chemical Society. 133: 18343-9. PMID 21928816 DOI: 10.1021/Ja207172S |
0.535 |
|
| 2011 |
Seyedsayamdost MR, Traxler MF, Zheng SL, Kolter R, Clardy J. Structure and biosynthesis of amychelin, an unusual mixed-ligand siderophore from Amycolatopsis sp. AA4. Journal of the American Chemical Society. 133: 11434-7. PMID 21699219 DOI: 10.1021/Ja203577E |
0.525 |
|
| 2011 |
Carr G, Seyedsayamdost MR, Chandler JR, Greenberg EP, Clardy J. Sources of diversity in bactobolin biosynthesis by Burkholderia thailandensis E264. Organic Letters. 13: 3048-51. PMID 21615115 DOI: 10.1021/Ol200922S |
0.577 |
|
| 2011 |
Minnihan EC, Seyedsayamdost MR, Uhlin U, Stubbe J. Kinetics of radical intermediate formation and deoxynucleotide production in 3-aminotyrosine-substituted Escherichia coli ribonucleotide reductases. Journal of the American Chemical Society. 133: 9430-40. PMID 21612216 DOI: 10.1021/Ja201640N |
0.551 |
|
| 2011 |
Seyedsayamdost MR, Case RJ, Kolter R, Clardy J. The Jekyll-and-Hyde chemistry of Phaeobacter gallaeciensis. Nature Chemistry. 3: 331-5. PMID 21430694 DOI: 10.1038/Nchem.1002 |
0.474 |
|
| 2011 |
Seyedsayamdost MR, Yee CS, Stubbe J. Use of 2,3,5-F(3)Y-β2 and 3-NH(2)Y-α2 to study proton-coupled electron transfer in Escherichia coli ribonucleotide reductase. Biochemistry. 50: 1403-11. PMID 21182280 DOI: 10.1021/Bi101319V |
0.51 |
|
| 2010 |
Seyedsayamdost MR, Chandler JR, Blodgett JA, Lima PS, Duerkop BA, Oinuma K, Greenberg EP, Clardy J. Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264. Organic Letters. 12: 716-9. PMID 20095633 DOI: 10.1021/Ol902751X |
0.803 |
|
| 2009 |
Minnihan EC, Seyedsayamdost MR, Stubbe J. Use of 3-aminotyrosine to examine the pathway dependence of radical propagation in Escherichia coli ribonucleotide reductase. Biochemistry. 48: 12125-32. PMID 19916558 DOI: 10.1021/Bi901439W |
0.496 |
|
| 2009 |
Seyedsayamdost MR, Argirevi? T, Minnihan EC, Stubbe J, Bennati M. Structural examination of the transient 3-aminotyrosyl radical on the PCET pathway of E. coli ribonucleotide reductase by multifrequency EPR spectroscopy. Journal of the American Chemical Society. 131: 15729-38. PMID 19821570 DOI: 10.1021/Ja903879W |
0.524 |
|
| 2009 |
Seyedsayamdost MR, Stubbe J. Replacement of Y730 and Y731 in the alpha2 subunit of Escherichia coli ribonucleotide reductase with 3-aminotyrosine using an evolved suppressor tRNA/tRNA-synthetase pair. Methods in Enzymology. 462: 45-76. PMID 19632469 DOI: 10.1016/S0076-6879(09)62003-6 |
0.572 |
|
| 2009 |
Offenbacher AR, Vassiliev IR, Seyedsayamdost MR, Stubbe J, Barry BA. Redox-linked structural changes in ribonucleotide reductase. Journal of the American Chemical Society. 131: 7496-7. PMID 19489635 DOI: 10.1021/Ja901908J |
0.521 |
|
| 2009 |
Reece SY, Lutterman DA, Seyedsayamdost MR, Stubbe J, Nocera DG. Re(bpy)(CO)3CN as a probe of conformational flexibility in a photochemical ribonucleotide reductase. Biochemistry. 48: 5832-8. PMID 19402704 DOI: 10.1021/Bi9005804 |
0.527 |
|
| 2007 |
Seyedsayamdost MR, Chan CT, Mugnaini V, Stubbe J, Bennati M. PELDOR spectroscopy with DOPA-beta2 and NH2Y-alpha2s: distance measurements between residues involved in the radical propagation pathway of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 129: 15748-9. PMID 18047343 DOI: 10.1021/Ja076459B |
0.505 |
|
| 2007 |
Seyedsayamdost MR, Xie J, Chan CT, Schultz PG, Stubbe J. Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation. Journal of the American Chemical Society. 129: 15060-71. PMID 17990884 DOI: 10.1021/Ja076043Y |
0.528 |
|
| 2007 |
Reece SY, Seyedsayamdost MR, Stubbe J, Nocera DG. Direct observation of a transient tyrosine radical competent for initiating turnover in a photochemical ribonucleotide reductase. Journal of the American Chemical Society. 129: 13828-30. PMID 17944464 DOI: 10.1021/Ja074452O |
0.554 |
|
| 2007 |
Reece SY, Seyedsayamdost MR, Stubbe J, Nocera DG. Photoactive peptides for light-initiated tyrosyl radical generation and transport into ribonucleotide reductase. Journal of the American Chemical Society. 129: 8500-9. PMID 17567129 DOI: 10.1021/Ja0704434 |
0.538 |
|
| 2007 |
Seyedsayamdost MR, Yee CS, Stubbe J. Site-specific incorporation of fluorotyrosines into the R2 subunit of E. coli ribonucleotide reductase by expressed protein ligation. Nature Protocols. 2: 1225-35. PMID 17546018 DOI: 10.1038/Nprot.2007.159 |
0.518 |
|
| 2007 |
Seyedsayamdost MR, Stubbe J. Forward and reverse electron transfer with the Y356DOPA-beta2 heterodimer of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 129: 2226-7. PMID 17279757 DOI: 10.1021/Ja0685607 |
0.52 |
|
| 2006 |
Reece SY, Seyedsayamdost MR, Stubbe J, Nocera DG. Electron transfer reactions of fluorotyrosyl radicals. Journal of the American Chemical Society. 128: 13654-5. PMID 17044670 DOI: 10.1021/Ja0636688 |
0.481 |
|
| 2006 |
Seyedsayamdost MR, Stubbe J. Site-specific replacement of Y356 with 3,4-dihydroxyphenylalanine in the beta2 subunit of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 128: 2522-3. PMID 16492021 DOI: 10.1021/Ja057776Q |
0.527 |
|
| 2006 |
Seyedsayamdost MR, Reece SY, Nocera DG, Stubbe J. Mono-, di-, tri-, and tetra-substituted fluorotyrosines: new probes for enzymes that use tyrosyl radicals in catalysis. Journal of the American Chemical Society. 128: 1569-79. PMID 16448128 DOI: 10.1021/Ja055926R |
0.492 |
|
| 2006 |
Seyedsayamdost MR, Yee CS, Reece SY, Nocera DG, Stubbe J. pH Rate profiles of FnY356-R2s (n = 2, 3, 4) in Escherichia coli ribonucleotide reductase: evidence that Y356 is a redox-active amino acid along the radical propagation pathway. Journal of the American Chemical Society. 128: 1562-8. PMID 16448127 DOI: 10.1021/Ja055927J |
0.497 |
|
| 2004 |
Guillén Schlippe YV, Riera TV, Seyedsayamdost MR, Hedstrom L. Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction. Biochemistry. 43: 4511-21. PMID 15078097 DOI: 10.1021/Bi035823Q |
0.323 |
|
| 2003 |
Yee CS, Seyedsayamdost MR, Chang MC, Nocera DG, Stubbe J. Generation of the R2 subunit of ribonucleotide reductase by intein chemistry: insertion of 3-nitrotyrosine at residue 356 as a probe of the radical initiation process. Biochemistry. 42: 14541-52. PMID 14661967 DOI: 10.1021/Bi0352365 |
0.638 |
|
| 2003 |
Gan L, Seyedsayamdost MR, Shuto S, Matsuda A, Petsko GA, Hedstrom L. The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase. Biochemistry. 42: 857-63. PMID 12549902 DOI: 10.1021/Bi0271401 |
0.332 |
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