Rafi Ahmed - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Immunology, Microbiology

463 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sacristán C, Youngblood BA, Lu P, Bally APR, Xu JX, McGary K, Hewitt SL, Boss JM, Skok JA, Ahmed R, Dustin ML. Chronic viral infection alters PD-1 locus subnuclear localization in cytotoxic CD8 T cells. Cell Reports. 43: 114547. PMID 39083377 DOI: 10.1016/j.celrep.2024.114547  0.453
2024 Dull PM, Achilles SL, Ahmed R, Barnabas RV, Campos NG, Chirgwin K, Cohen JA, de Sanjosé S, Doorbar J, Einstein MH, Emerson CI, Gottlieb SL, Hildesheim A, Qiao Y, Ruff P, et al. Meeting report: Considerations for trial design and endpoints in licensing therapeutic HPV16/18 vaccines to prevent cervical cancer. Vaccine. PMID 39004526 DOI: 10.1016/j.vaccine.2024.07.001  0.7
2024 McManus DT, Valanparambil RM, Medina CB, Hu Y, Scharer CD, Sobierajska E, Chang DY, Wieland A, Lee J, Nasti TH, Hashimoto M, Ross JL, Prokhnevska N, Cardenas MA, Gill AL, ... ... Ahmed R, et al. Early generation of a precursor CD8 T cell that can adapt to acute or chronic viral infection. Research Square. PMID 38410458 DOI: 10.21203/rs.3.rs-3922168/v1  0.726
2024 van der Heide V, Davenport B, Cubitt B, Roudko V, Choo D, Humblin E, Jhun K, Angeliadis K, Dawson T, Furtado G, Kamphorst A, Ahmed R, de la Torre JC, Homann D. Functional impairment of "helpless" CD8 memory T cells is transient and driven by prolonged but finite cognate antigen presentation. Biorxiv : the Preprint Server For Biology. PMID 38328184 DOI: 10.1101/2024.01.22.576725  0.799
2024 Abadie K, Clark EC, Valanparambil RM, Ukogu O, Yang W, Daza RM, Ng KKH, Fathima J, Wang AL, Lee J, Nasti TH, Bhandoola A, Nourmohammad A, Ahmed R, Shendure J, et al. Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision. Immunity. PMID 38301652 DOI: 10.1016/j.immuni.2023.12.006  0.446
2023 Hashimoto M, Ramalingam SS, Ahmed R. Harnessing CD8 T cell responses using PD-1-IL-2 combination therapy. Trends in Cancer. PMID 38129234 DOI: 10.1016/j.trecan.2023.11.008  0.396
2023 Chen C, Zheng H, Horwitz EM, Ando S, Araki K, Zhao P, Li Z, Ford ML, Ahmed R, Qu CK. Mitochondrial metabolic flexibility is critical for CD8 T cell antitumor immunity. Science Advances. 9: eadf9522. PMID 38055827 DOI: 10.1126/sciadv.adf9522  0.363
2023 Mariniello A, Nasti TH, Chang DY, Hashimoto M, Malik S, McManus D, Lee J, McGuire D, Cardenas MA, Umana P, Nicolini V, Antia R, Saha A, Buchwald Z, Kissick H, ... ... Ahmed R, et al. Platinum-based chemotherapy attenuates the effector response of CD8 T cells to concomitant PD-1 blockade. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37992307 DOI: 10.1158/1078-0432.CCR-23-1316  0.323
2023 Im SJ, Obeng RC, Nasti TH, McManus D, Kamphorst AO, Gunisetty S, Prokhnevska N, Carlisle JW, Yu K, Sica GL, Cardozo LE, Gonçalves ANA, Kissick HT, Nakaya HI, Ramalingam SS, ... Ahmed R, et al. Characteristics and anatomic location of PD-1TCF1 stem-like CD8 T cells in chronic viral infection and cancer. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221985120. PMID 37782797 DOI: 10.1073/pnas.2221985120  0.472
2023 Wang PH, Washburn RS, Mariuzza DL, Lin WW, Gill AL, Ahmed R, Reiner SL. Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating T cells. Cell Reports. 42: 113155. PMID 37756164 DOI: 10.1016/j.celrep.2023.113155  0.483
2023 Gill AL, Wang PH, Lee J, Hudson WH, Ando S, Araki K, Hu Y, Wieland A, Im S, Gavora A, Medina CB, Freeman GJ, Hashimoto M, Reiner SL, Ahmed R. PD-1 blockade increases the self-renewal of stem-like CD8 T cells to compensate for their accelerated differentiation into effectors. Science Immunology. 8: eadg0539. PMID 37624909 DOI: 10.1126/sciimmunol.adg0539  0.429
2023 Mayer-Blackwell K, Ryu H, Codd AS, Parks KR, MacMillan HR, Cohen KW, Stewart TL, Seese A, Lemos MP, De Rosa SC, Czartoski JL, Moodie Z, Nguyen LT, McGuire DJ, Ahmed R, et al. mRNA vaccination boosts S-specific T cell memory and promotes expansion of CD45RA T-like CD8 T cells in COVID-19 recovered individuals. Cell Reports. Medicine. 101149. PMID 37552991 DOI: 10.1016/j.xcrm.2023.101149  0.526
2022 Gill AL, Hudson WH, Valanparambil RM, Ahn E, McGuire DJ, Wieland A, McManus DT, Kissick HT, Akondy RS, Ahmed R. Longitudinal Analysis of the Phenotype, Transcriptional Profile, and Anatomic Location of Memory CD8 T Cell Subsets after Acute Viral Infection. Journal of Virology. e0155622. PMID 36541799 DOI: 10.1128/jvi.01556-22  0.469
2022 Azeem MI, Nooka AK, Shanmugasundaram U, Cheedarla N, Potdar S, Manalo RJ, Moreno A, Switchenko JM, Cheedarla S, Doxie DB, Radzievski R, Ellis ML, Manning KE, Wali B, Valanparambil RM, ... ... Ahmed R, et al. Impaired SARS-CoV-2 variant neutralization and CD8+ T cell responses following 3 doses of mRNA vaccines in myeloma: correlation with breakthrough infections. Blood Cancer Discovery. PMID 36511813 DOI: 10.1158/2643-3230.BCD-22-0173  0.416
2022 Künzli M, O'Flanagan SD, LaRue M, Talukder P, Dileepan T, Stolley JM, Soerens AG, Quarnstrom CF, Wijeyesinghe S, Ye Y, McPartlan JS, Mitchell JS, Mandl CW, Vile R, Jenkins MK, ... Ahmed R, et al. Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells. Science Immunology. 7: eadd3075. PMID 36459542 DOI: 10.1126/sciimmunol.add3075  0.5
2022 Ando S, Perkins C, Sajiki Y, Chastain C, Valanparambil RM, Wieland A, Hudson WH, Hashimoto M, Ramalingam SS, Freeman GJ, Ahmed R, Araki K. mTOR regulates T cell exhaustion and PD-1 targeted immunotherapy response during chronic viral infection. The Journal of Clinical Investigation. PMID 36378537 DOI: 10.1172/JCI160025  0.407
2022 Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, Lee J, McManus DT, Ross JL, Im SJ, Lee J, ... ... Ahmed R, et al. PD-1 combination therapy with IL-2 modifies CD8 T cell exhaustion program. Nature. PMID 36171288 DOI: 10.1038/s41586-022-05257-0  0.767
2022 Codarri Deak L, Nicolini V, Hashimoto M, Karagianni M, Schwalie PC, Lauener L, Varypataki EM, Richard M, Bommer E, Sam J, Joller S, Perro M, Cremasco F, Kunz L, Yanguez E, ... ... Ahmed R, et al. PD-1-cis IL-2R agonism yields better effectors from stem-like CD8 T cells. Nature. PMID 36171284 DOI: 10.1038/s41586-022-05192-0  0.37
2022 Hu Y, Hudson WH, Kissick HT, Medina CB, Baptista AP, Ma C, Liao W, Germain RN, Turley SJ, Zhang N, Ahmed R. TGF-β regulates the stem-like state of PD-1+ TCF-1+ virus-specific CD8 T cells during chronic infection. The Journal of Experimental Medicine. 219. PMID 35980386 DOI: 10.1084/jem.20211574  0.454
2022 Velu V, Titanji K, Ahmed H, Shetty RD, Chennareddi LS, Freeman GJ, Ahmed R, Amara RR. PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202148119. PMID 35939675 DOI: 10.1073/pnas.2202148119  0.428
2022 Kissick H, Ahmed R. New epigenetic regulators of T cell exhaustion. Cancer Cell. 40: 708-710. PMID 35820395 DOI: 10.1016/j.ccell.2022.06.008  0.405
2022 Sudmeier LJ, Hoang KB, Nduom EK, Wieland A, Neill SG, Schniederjan MJ, Ramalingam SS, Olson JJ, Ahmed R, Hudson WH. Distinct phenotypic states and spatial distribution of CD8 T cell clonotypes in human brain metastases. Cell Reports. Medicine. 3: 100620. PMID 35584630 DOI: 10.1016/j.xcrm.2022.100620  0.446
2022 Langley WA, Wieland A, Ahmed H, Rasheed MAU, Davis CW, Sewatanon J, Mueller SN, Shlomchik MJ, Zarnitsyna VI, Antia R, Ahmed R. Persistence of Virus-Specific Antibody after Depletion of Memory B Cells. Journal of Virology. e0002622. PMID 35404084 DOI: 10.1128/jvi.00026-22  0.797
2022 Su FY, Zhao QH, Dahotre SN, Gamboa L, Bawage SS, Silva Trenkle AD, Zamat A, Phuengkham H, Ahmed R, Santangelo PJ, Kwong GA. In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles. Science Advances. 8: eabm7950. PMID 35196075 DOI: 10.1126/sciadv.abm7950  0.743
2021 Zarnitsyna VI, Akondy RS, Ahmed H, McGuire DJ, Zarnitsyn VG, Moore M, Johnson PLF, Ahmed R, Li KW, Hellerstein MK, Antia R. Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination. Plos Computational Biology. 17: e1009468. PMID 34648489 DOI: 10.1371/journal.pcbi.1009468  0.459
2021 Rahman SA, Yagnik B, Bally AP, Morrow KN, Wang S, Vanderford TH, Freeman GJ, Ahmed R, Amara RR. PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8 T cells in lymphoid tissue. Science Immunology. 6: eabh3034. PMID 34516743 DOI: 10.1126/sciimmunol.abh3034  0.392
2021 Eberhardt CS, Kissick HT, Patel MR, Cardenas MA, Prokhnevska N, Obeng RC, Nasti TH, Griffith CC, Im SJ, Wang X, Shin DM, Carrington M, Chen ZG, Sidney J, Sette A, ... ... Ahmed R, et al. Functional HPV-specific PD-1 stem-like CD8 T cells in head and neck cancer. Nature. PMID 34471285 DOI: 10.1038/s41586-021-03862-z  0.396
2021 Cohen KW, Linderman SL, Moodie Z, Czartoski J, Lai L, Mantus G, Norwood C, Nyhoff LE, Edara VV, Floyd K, De Rosa SC, Ahmed H, Whaley R, Patel SN, Prigmore B, ... ... Ahmed R, et al. Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells. Cell Reports. Medicine. 100354. PMID 34250512 DOI: 10.1016/j.xcrm.2021.100354  0.539
2021 Cohen KW, Linderman SL, Moodie Z, Czartoski J, Lai L, Mantus G, Norwood C, Nyhoff LE, Edara VV, Floyd K, De Rosa SC, Ahmed H, Whaley R, Patel SN, Prigmore B, ... ... Ahmed R, et al. Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells. Cell Reports. Medicine. 100354. PMID 34250512 DOI: 10.1016/j.xcrm.2021.100354  0.539
2021 Wieland A, Ahmed R. Immunological lessons from CD28 deficiency in humans. Cell. 184: 3595-3597. PMID 34242561 DOI: 10.1016/j.cell.2021.06.014  0.416
2021 Wieland A, Ahmed R. Immunological lessons from CD28 deficiency in humans. Cell. 184: 3595-3597. PMID 34242561 DOI: 10.1016/j.cell.2021.06.014  0.416
2021 Mantus G, Nyhoff LE, Kauffman RC, Edara VV, Lai L, Floyd K, Shi PY, Menachery VD, Edupuganti S, Scherer EM, Kay A, McNair N, Anderson EJ, Rouphael N, Ahmed R, et al. Evaluation of Cellular and Serological Responses to Acute SARS-CoV-2 Infection Demonstrates the Functional Importance of the Receptor-Binding Domain. Journal of Immunology (Baltimore, Md. : 1950). PMID 33952616 DOI: 10.4049/jimmunol.2001420  0.344
2021 Cohen KW, Linderman SL, Moodie Z, Czartoski J, Lai L, Mantus G, Norwood C, Nyhoff LE, Edara VV, Floyd K, De Rosa SC, Ahmed H, Whaley R, Patel SN, Prigmore B, ... ... Ahmed R, et al. Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells. Medrxiv : the Preprint Server For Health Sciences. PMID 33948610 DOI: 10.1101/2021.04.19.21255739  0.54
2020 Kofman A, Linderman S, Su K, Purpura LJ, Ervin E, Brown S, Morales-Betoulle M, Graziano J, Cannon DL, Klena JD, Desamu-Thorpe R, Fankhauser J, Orone R, Soka M, Glaybo U, ... ... Ahmed R, et al. Characteristics of Ebola Virus Disease Survivor Blood and Semen in Liberia: Serology and RT-PCR. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32894277 DOI: 10.1093/Cid/Ciaa1331  0.325
2020 Davis CW, Jackson KJL, McCausland MM, Darce J, Chang C, Linderman SL, Chennareddy C, Gerkin R, Brown SJ, Wrammert J, Mehta AK, Cheung WC, Boyd SD, Waller EK, Ahmed R. Influenza vaccine-induced human bone marrow plasma cells decline within a year after vaccination. Science (New York, N.Y.). PMID 32792465 DOI: 10.1126/Science.Aaz8432  0.341
2020 Chang YM, Wieland A, Li ZR, Im SJ, McGuire DJ, Kissick HT, Antia R, Ahmed R. T cell receptor diversity and lineage relationship between virus-specific CD8 T cell subsets during chronic LCMV infection. Journal of Virology. PMID 32759317 DOI: 10.1128/Jvi.00935-20  0.587
2020 Ellebedy AH, Nachbagauer R, Jackson KJL, Dai YN, Han J, Alsoussi WB, Davis CW, Stadlbauer D, Rouphael N, Chromikova V, McCausland M, Chang CY, Cortese M, Bower M, Chennareddy C, ... ... Ahmed R, et al. Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans. Proceedings of the National Academy of Sciences of the United States of America. PMID 32661157 DOI: 10.1073/Pnas.1906613117  0.42
2020 Carnathan DG, Kaushik K, Ellebedy AH, Enemuo CA, Gebru EH, Dhadvai P, Rasheed MAU, Pauthner MG, Ozorowski G, Ahmed R, Burton DR, Ward AB, Silvestri G, Crotty S, Locci M. Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers. Frontiers in Immunology. 11: 1213. PMID 32612608 DOI: 10.3389/Fimmu.2020.01213  0.494
2020 Kasturi SP, Rasheed MAU, Havenar-Daughton C, Pham M, Legere T, Sher ZJ, Kovalenkov Y, Gumber S, Huang JY, Gottardo R, Fulp W, Sato A, Sawant S, Stanfield-Oakley S, Yates N, ... ... Ahmed R, et al. 3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates. Science Immunology. 5. PMID 32561559 DOI: 10.1126/Sciimmunol.Abb1025  0.411
2020 Jella KK, Nasti TH, Li Z, Lawson DH, Switchenko JM, Ahmed R, Dynan WS, Khan MK. Exosome-containing preparations from post-irradiated mouse melanoma cells delay melanoma growth in vivo by a natural killer cell-dependent mechanism. International Journal of Radiation Oncology, Biology, Physics. PMID 32561502 DOI: 10.1016/J.Ijrobp.2020.06.016  0.433
2020 Eberhardt CS, Wieland A, Nasti TH, Grifoni A, Wilson E, Schmid DS, Pulendran B, Sette A, Waller EK, Rouphael N, Ahmed R. Persistence of varicella zoster virus specific plasma cells in adult human bone marrow following childhood vaccination. Journal of Virology. PMID 32321817 DOI: 10.1128/Jvi.02127-19  0.566
2020 Bradley T, Kuraoka M, Yeh CH, Tian M, Chen H, Cain DW, Chen X, Cheng C, Ellebedy AH, Parks R, Barr M, Sutherland LL, Scearce RM, Bowman CM, Bouton-Verville H, ... ... Ahmed R, et al. Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948. PMID 32075963 DOI: 10.1038/S41467-020-14670-W  0.374
2020 Im SJ, Konieczny BT, Hudson WH, Masopust D, Ahmed R. PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32034098 DOI: 10.1073/Pnas.1917298117  0.621
2020 Bovay A, Nassiri S, Maby-El Hajjami H, Marcos Mondéjar P, Akondy RS, Ahmed R, Lawson B, Speiser DE, Fuertes Marraco SA. Minimal immune response to booster vaccination against Yellow Fever associated with pre-existing antibodies. Vaccine. 38: 2172-2182. PMID 32008879 DOI: 10.1016/J.Vaccine.2020.01.045  0.351
2019 Ahmed R, Ford ML, Sanz I. Regulation of T and B cell responses to chronic antigenic stimulation during Infection, autoimmunity and transplantation. Immunological Reviews. 292: 5-8. PMID 31883175 DOI: 10.1111/Imr.12836  0.465
2019 Hudson WH, Gensheimer J, Hashimoto M, Wieland A, Valanparambil RM, Li P, Lin JX, Konieczny BT, Im SJ, Freeman GJ, Leonard WJ, Kissick HT, Ahmed R. Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1 Stem-like CD8 T Cells during Chronic Infection. Immunity. PMID 31810882 DOI: 10.1016/J.Immuni.2019.11.002  0.573
2019 Rasheed MAU, Hickman CJ, McGrew M, Sowers SB, Mercader S, Hopkins A, Grimes V, Yu T, Wrammert J, Mulligan MJ, Bellini WJ, Rota PA, Orenstein WA, Ahmed R, Edupuganti S. Decreased humoral immunity to mumps in young adults immunized with MMR vaccine in childhood. Proceedings of the National Academy of Sciences of the United States of America. PMID 31481612 DOI: 10.1073/Pnas.1905570116  0.369
2019 Petermann F, Pękowska A, Johnson CA, Jankovic D, Shih HY, Jiang K, Hudson WH, Brooks SR, Sun HW, Villarino AV, Yao C, Singleton K, Akondy RS, Kanno Y, Sher A, ... ... Ahmed R, et al. The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. Molecular Cell. PMID 31377117 DOI: 10.1016/J.Molcel.2019.06.025  0.335
2019 Jadhav RR, Im SJ, Hu B, Hashimoto M, Li P, Lin JX, Leonard WJ, Greenleaf WJ, Ahmed R, Goronzy JJ. Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade. Proceedings of the National Academy of Sciences of the United States of America. PMID 31227606 DOI: 10.1073/Pnas.1903520116  0.609
2019 Moore JR, Ahmed H, McGuire D, Akondy R, Ahmed R, Antia R. Dependence of CD8 T Cell Response upon Antigen Load During Primary Infection : Analysis of Data from Yellow Fever Vaccination. Bulletin of Mathematical Biology. PMID 31165405 DOI: 10.1007/S11538-019-00618-9  0.541
2019 Davis CW, Jackson KJL, McElroy AK, Halfmann P, Huang J, Chennareddy C, Piper AE, Leung Y, Albariño CG, Crozier I, Ellebedy AH, Sidney J, Sette A, Yu T, Nielsen SCA, ... ... Ahmed R, et al. Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection. Cell. PMID 31104840 DOI: 10.1016/J.Cell.2019.04.036  0.418
2019 Sullivan NL, Eberhardt CS, Wieland A, Vora KA, Pulendran B, Ahmed R. Understanding the immunology of the Zostavax shingles vaccine. Current Opinion in Immunology. 59: 25-30. PMID 30970291 DOI: 10.1016/J.Coi.2019.02.005  0.396
2019 Gao J, Couzens L, Burke DF, Wan H, Wilson P, Memoli MJ, Xu X, Harvey R, Wrammert J, Ahmed R, Taubenberger JK, Smith DJ, Fouchier RAM, Eichelberger MC. Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies. Mbio. 10. PMID 30967460 DOI: 10.1128/Mbio.00307-19  0.368
2019 Sukhatme VV, Ramalingam SS, Ahmed R, Sukhatme VP. Repurposing Food and Drug Administration-Approved Drugs to Promote Antitumor Immunity. Cancer Journal (Sudbury, Mass.). 25: 88-99. PMID 30896530 DOI: 10.1097/Ppo.0000000000000368  0.33
2019 Henry C, Zheng NY, Huang M, Cabanov A, Rojas KT, Kaur K, Andrews SF, Palm AE, Chen YQ, Li Y, Hoskova K, Utset HA, Vieira MC, Wrammert J, Ahmed R, et al. Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals. Cell Host & Microbe. PMID 30795982 DOI: 10.1016/J.Chom.2019.01.002  0.39
2019 Wieland A, Ahmed R. Fc Receptors in Antimicrobial Protection. Current Topics in Microbiology and Immunology. PMID 30790076 DOI: 10.1007/82_2019_154  0.338
2019 Tesini BL, Kanagaiah P, Wang J, Hahn M, Halliley JL, Chaves FA, Nguyen PQT, Nogales A, DeDiego ML, Anderson CS, Ellebedy AH, Strohmeier S, Krammer F, Yang H, Bandyopadhyay S, ... Ahmed R, et al. Broad hemagglutinin-specific memory B cell expansion by seasonal influenza virus infection reflects early-life imprinting and adaptation to the infecting virus. Journal of Virology. PMID 30728266 DOI: 10.1128/Jvi.00169-19  0.448
2019 Chang A, Payne JB, Allen PB, Koff JL, Ahmed R, Flowers CR, Bednarczyk RA. Influenza Vaccination Documentation Rates During the First Year After Diagnosis of Diffuse Large B Cell Lymphoma. Clinical Lymphoma, Myeloma & Leukemia. PMID 30686773 DOI: 10.1016/J.Clml.2018.12.018  0.328
2019 Sullivan NL, Eberhardt CS, Wieland A, Akondy RS, Yi J, McElroy AK, Ahmed R. Characterization of Virus-specific Immune Response During Varicella Zoster Virus Encephalitis in a Young Adult. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30668661 DOI: 10.1093/Cid/Ciy984  0.476
2019 Gangappa S, Wrammert J, Wang D, Li ZN, Liepkalns JS, Cao W, Chen J, Levine MZ, Stevens J, Sambhara S, Begley B, Mehta A, Pearson TC, Ahmed R, Larsen CP. Kinetics of antibody response to influenza vaccination in renal transplant recipients. Transplant Immunology. PMID 30664927 DOI: 10.1016/J.Trim.2019.01.001  0.301
2019 Gunisetty S, Nayak K, Chandra Rai R, Chawla Y, Elluri SR, Aggarwal C, Maheshwari D, Panda H, Ansari NA, Singh P, Kaur M, Dixit K, Sharma P, Bhatnagar P, Priyamvada L, ... ... Ahmed R, et al. Analysis of dengue specific memory B cells, neutralizing antibodies and binding antibodies in healthy adults from India. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. PMID 30658170 DOI: 10.1016/J.Ijid.2019.01.018  0.412
2019 Hudson WH, Prokhnevska N, Gensheimer J, Akondy R, McGuire DJ, Ahmed R, Kissick HT. Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8 T cells. Nature Communications. 10: 196. PMID 30643116 DOI: 10.1038/S41467-018-07956-7  0.573
2019 Bloom B, Ahmed R. Immunity to infection. Current Opinion in Immunology. 10: 419-421. PMID 9751649 DOI: 10.1016/S0952-7915(98)80115-5  0.355
2019 Hudson WH, Gensheimer JL, Kissick HT, Ahmed R. Abstract A196: Systematic identification of markers and drug targets on exhausted CD8+ T-cells Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A196  0.592
2019 Buchwald ZS, Nasti TH, Eberhardt CS, Wieland A, Lawson D, Curran W, Ahmed R, Khan MK. Abstract 526: Tumor-draining lymph node irradiation reduces tumor-infiltrating stem-like CD8+T-cells and abrogates the abscopal effect Cancer Research. 79: 526-526. DOI: 10.1158/1538-7445.Am2019-526  0.488
2018 Kim C, Hu B, Jadhav RR, Jin J, Zhang H, Cavanagh MM, Akondy RS, Ahmed R, Weyand CM, Goronzy JJ. Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells. Cell Reports. 25: 2148-2162.e5. PMID 30463012 DOI: 10.1016/J.Celrep.2018.10.074  0.452
2018 Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, ... ... Ahmed R, et al. In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model. Cell Reports. 25: 1982-1993.e4. PMID 30428362 DOI: 10.1016/J.Celrep.2018.10.062  0.318
2018 Wieland A, Kamphorst AO, Valanparambil RM, Han JH, Xu X, Choudhury BP, Ahmed R. Enhancing FcγR-mediated antibody effector function during persistent viral infection. Science Immunology. 3. PMID 30242080 DOI: 10.1126/Sciimmunol.Aao3125  0.42
2018 Mylvaganam GH, Chea LS, Tharp GK, Hicks S, Velu V, Iyer SS, Deleage C, Estes JD, Bosinger SE, Freeman GJ, Ahmed R, Amara RR. Combination anti-PD-1 and antiretroviral therapy provides therapeutic benefit against SIV. Jci Insight. 3. PMID 30232277 DOI: 10.1172/Jci.Insight.122940  0.516
2018 Wieland A, Kamphorst AO, Adsay NV, Masor JJ, Sarmiento J, Nasti TH, Darko S, Douek DC, Xue Y, Curran WJ, Lawson DH, Ahmed R. T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient. Cancer Immunology, Immunotherapy : Cii. PMID 30167863 DOI: 10.1007/S00262-018-2228-7  0.52
2018 Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, ... ... Ahmed R, et al. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 174: 938-952.e13. PMID 30096313 DOI: 10.1016/J.Cell.2018.07.033  0.361
2018 Kityo C, Makamdop KN, Rothenberger M, Chipman JG, Hoskuldsson T, Beilman GJ, Grzywacz B, Mugyenyi P, Ssali F, Akondy RS, Anderson J, Schmidt TE, Reimann T, Callisto SP, Schoephoerster J, ... ... Ahmed R, et al. Lymphoid tissue fibrosis is associated with impaired vaccine responses. The Journal of Clinical Investigation. PMID 29781814 DOI: 10.1172/Jci97377  0.439
2018 Sullivan NL, Reuter-Monslow MA, Sei J, Durr E, Davis CW, Chang C, McCausland M, Wieland A, Krah D, Rouphael N, Mehta AK, Mulligan MJ, Pulendran B, Ahmed R, Vora KA. . Journal of Virology. PMID 29743372 DOI: 10.1128/Jvi.00269-18  0.44
2018 Ahn E, Araki K, Hashimoto M, Li W, Riley JL, Cheung J, Sharpe AH, Freeman GJ, Irving BA, Ahmed R. Role of PD-1 during effector CD8 T cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29654146 DOI: 10.1073/Pnas.1718217115  0.525
2018 Chen YQ, Wohlbold TJ, Zheng NY, Huang M, Huang Y, Neu KE, Lee J, Wan H, Rojas KT, Kirkpatrick E, Henry C, Palm AE, Stamper CT, Lan LY, Topham DJ, ... ... Ahmed R, et al. Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies. Cell. 173: 417-429.e10. PMID 29625056 DOI: 10.1016/J.Cell.2018.03.030  0.37
2018 Hashimoto M, Kamphorst AO, Im SJ, Kissick HT, Pillai RN, Ramalingam SS, Araki K, Ahmed R. CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions. Annual Review of Medicine. 69: 301-318. PMID 29414259 DOI: 10.1146/Annurev-Med-012017-043208  0.566
2018 Ramasamy V, Arora U, Shukla R, Poddar A, Shanmugam RK, White LJ, Mattocks MM, Raut R, Perween A, Tyagi P, de Silva AM, Bhaumik SK, Kaja MK, Villinger F, Ahmed R, et al. A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice. Plos Neglected Tropical Diseases. 12: e0006191. PMID 29309412 DOI: 10.1371/Journal.Pntd.0006191  0.373
2018 Nachbagauer R, Shore D, Yang H, Johnson SK, Gabbard JD, Tompkins SM, Wrammert J, Wilson PC, Stevens J, Ahmed R, Krammer F, Ellebedy AH. Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. Journal of Virology. 92. DOI: 10.2210/Pdb6B3M/Pdb  0.343
2018 Nasti T, Im S, Kissick H, Daugherty C, Lawson DH, Ahmed R, Khan MK. Anti-PD1 (muDX 400) therapy given after radiation has greatest impact on (CD8+ Tim3- CD73+) stem cell like cells: Implications for improved clinical trial design incorporating radiation and anti-PD1. Journal of Clinical Oncology. 36. DOI: 10.1200/Jco.2018.36.15_Suppl.E21525  0.481
2018 Kim S, Khoriaty R, Valanparambil R, Wu J, Taylor A, Fujiwara H, Peltier D, Sun Y, Henig I, Zajac C, Oravecz-Wilson K, Brabbs S, Ahmed R, Ginsburg D, Reddy P. Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity Blood. 132: 859-859. DOI: 10.1182/Blood-2018-99-111628  0.45
2017 Priyamvada L, Suthar MS, Ahmed R, Wrammert J. Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity. The Journal of Infectious Diseases. 216: S906-S911. PMID 29267924 DOI: 10.1093/Infdis/Jix513  0.434
2017 Akondy RS, Fitch M, Edupuganti S, Yang S, Kissick HT, Li KW, Youngblood BA, Abdelsamed HA, McGuire DJ, Cohen KW, Alexe G, Nagar S, McCausland MM, Gupta S, Tata P, ... ... Ahmed R, et al. Origin and differentiation of human memory CD8 T cells after vaccination. Nature. PMID 29236685 DOI: 10.1038/Nature24633  0.633
2017 Youngblood B, Hale JS, Kissick HT, Ahn E, Xu X, Wieland A, Araki K, West EE, Ghoneim HE, Fan Y, Dogra P, Davis CW, Konieczny BT, Antia R, Cheng X, ... Ahmed R, et al. Effector CD8 T cells dedifferentiate into long-lived memory cells. Nature. PMID 29236683 DOI: 10.1038/Nature25144  0.776
2017 Feinberg MB, Ahmed R. Advancing dengue vaccine development. Science (New York, N.Y.). 358: 865-866. PMID 29146795 DOI: 10.1126/Science.Aaq0215  0.359
2017 Moore J, Ahmed H, Jia J, Akondy R, Ahmed R, Antia R. What Controls the Acute Viral Infection Following Yellow Fever Vaccination? Bulletin of Mathematical Biology. PMID 29110131 DOI: 10.1007/S11538-017-0365-3  0.402
2017 Hashimoto M, Im SJ, Araki K, Ahmed R. Cytokine-Mediated Regulation of CD8 T-Cell Responses During Acute and Chronic Viral Infection. Cold Spring Harbor Perspectives in Biology. PMID 29101105 DOI: 10.1101/Cshperspect.A028464  0.547
2017 Araki K, Morita M, Bederman AG, Konieczny BT, Kissick HT, Sonenberg N, Ahmed R. Translation is actively regulated during the differentiation of CD8(+) effector T cells. Nature Immunology. PMID 28714979 DOI: 10.1038/Ni.3795  0.597
2017 Czakó R, Vogel L, Lamirande EW, Bock KW, Moore IN, Ellebedy AH, Ahmed R, Mehle A, Subbarao K. In Vivo Imaging of Influenza Virus Infection in Immunized Mice. Mbio. 8. PMID 28559489 DOI: 10.1128/Mbio.00714-17  0.363
2017 Li S, Sullivan NL, Rouphael N, Yu T, Banton S, Maddur MS, McCausland M, Chiu C, Canniff J, Dubey S, Liu K, Tran V, Hagan T, Duraisingham S, Wieland A, ... ... Ahmed R, et al. Metabolic Phenotypes of Response to Vaccination in Humans. Cell. PMID 28502771 DOI: 10.1016/J.Cell.2017.04.026  0.448
2017 Priyamvada L, Hudson W, Ahmed R, Wrammert J. Humoral cross-reactivity between Zika and dengue viruses: implications for protection and pathology. Emerging Microbes & Infections. 6: e33. PMID 28487557 DOI: 10.1038/Emi.2017.42  0.355
2017 Kamphorst AO, Pillai RN, Yang S, Nasti TH, Akondy RS, Wieland A, Sica GL, Yu K, Koenig L, Patel NT, Behera M, Wu H, McCausland M, Chen Z, Zhang C, ... ... Ahmed R, et al. Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients. Proceedings of the National Academy of Sciences of the United States of America. PMID 28446615 DOI: 10.1073/Pnas.1705327114  0.47
2017 Sullivan H, Arthur C, Wieland A, Ahmed R, Stowell S. Viral Infection Prevents Hemolytic Transfusion Reactions Following Incompatible Red Blood Cell Transfusion. American Journal of Clinical Pathology. PMID 28340097 DOI: 10.1093/Ajcp/Aqw191.036  0.328
2017 Kamphorst AO, Wieland A, Nasti T, Yang S, Zhang R, Barber DL, Konieczny BT, Daugherty CZ, Koenig L, Yu K, Sica GL, Sharpe AH, Freeman GJ, Blazar BR, Turka LA, ... ... Ahmed R, et al. Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent. Science (New York, N.Y.). PMID 28280249 DOI: 10.1126/Science.Aaf0683  0.501
2017 Kazmin D, Nakaya HI, Lee EK, Johnson MJ, van der Most R, van den Berg RA, Ballou WR, Jongert E, Wille-Reece U, Ockenhouse C, Aderem A, Zak DE, Sadoff J, Hendriks J, Wrammert J, ... Ahmed R, et al. Systems analysis of protective immune responses to RTS,S malaria vaccination in humans. Proceedings of the National Academy of Sciences of the United States of America. PMID 28193898 DOI: 10.1073/Pnas.1621489114  0.424
2017 Mylvaganam GH, Rios D, Abdelaal HM, Iyer S, Tharp G, Mavinger M, Hicks S, Chahroudi A, Ahmed R, Bosinger SE, Williams IR, Skinner PJ, Velu V, Amara RR. Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 28159893 DOI: 10.1073/Pnas.1621418114  0.613
2017 Wang TT, Sewatanon J, Memoli MJ, Wrammert J, Bournazos S, Bhaumik SK, Pinsky BA, Chokephaibulkit K, Onlamoon N, Pattanapanyasat K, Taubenberger JK, Ahmed R, Ravetch JV. IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity. Science (New York, N.Y.). 355: 395-398. PMID 28126818 DOI: 10.1126/Science.Aai8128  0.345
2017 Pillai RN, Kamphorst AO, Yang S, Owonikoko TK, Sica G, Nasti T, Akondy R, Wieland A, Wu H, Patel N, Yu K, Koenig L, Behera M, McCausland M, Khuri FR, ... Ahmed R, et al. Early proliferation of PD-1+ CD8 T cells in peripheral blood as predictive of response to PD-1 inhibition for patients with advanced NSCLC. Journal of Clinical Oncology. 35: e20648-e20648. DOI: 10.1200/Jco.2017.35.15_Suppl.E20648  0.383
2016 Lee J, Hashimoto M, Im SJ, Araki K, Jin HT, Davis CW, Konieczny BT, Spies GA, McElrath MJ, Ahmed R. Adenovirus serotype 5 vaccination results in suboptimal CD4 T helper 1 responses in mice. Journal of Virology. PMID 28003483 DOI: 10.1128/Jvi.01132-16  0.554
2016 Ye L, Lee J, Xu L, Mohammed AU, Li W, Hale JS, Tan WG, Wu T, Davis CW, Ahmed R, Araki K. mTOR promotes anti-viral humoral immunity by differentially regulating CD4 helper T cell and B cell responses. Journal of Virology. PMID 27974559 DOI: 10.1128/Jvi.01653-16  0.572
2016 Havenar-Daughton C, Carnathan DG, Torrents de la Peña A, Pauthner M, Briney B, Reiss SM, Wood JS, Kaushik K, van Gils MJ, Rosales SL, van der Woude P, Locci M, Le KM, de Taeye SW, Sok D, ... ... Ahmed R, et al. Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer. Cell Reports. 17: 2195-2209. PMID 27880897 DOI: 10.1016/J.Celrep.2016.10.085  0.378
2016 Chandele A, Sewatanon J, Gunisetty S, Singla M, Onlamoon N, Akondy RS, Kissick HT, Nayak K, Reddy ES, Kalam H, Kumar D, Verma A, Panda H, Wang S, Angkasekwinai N, ... ... Ahmed R, et al. Characterization of human CD8 T cell responses in dengue virus infected patients from India. Journal of Virology. PMID 27707928 DOI: 10.1128/Jvi.01424-16  0.578
2016 Ellebedy AH, Jackson KJ, Kissick HT, Nakaya HI, Davis CW, Roskin KM, McElroy AK, Oshansky CM, Elbein R, Thomas S, Lyon GM, Spiropoulou CF, Mehta AK, Thomas PG, Boyd SD, ... Ahmed R, et al. Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination. Nature Immunology. PMID 27525369 DOI: 10.1038/Ni.3533  0.486
2016 Im SJ, Hashimoto M, Gerner MY, Lee J, Kissick HT, Burger MC, Shan Q, Hale JS, Lee J, Nasti TH, Sharpe AH, Freeman GJ, Germain RN, Nakaya HI, Xue HH, ... Ahmed R, et al. Defining CD8(+) T cells that provide the proliferative burst after PD-1 therapy. Nature. PMID 27501248 DOI: 10.1038/Nature19330  0.596
2016 Ahn E, Youngblood B, Lee J, Lee J, Sarkar S, Ahmed R. Demethylation of the PD-1 promoter is imprinted during the effector phase of CD8 T cell exhaustion. Journal of Virology. PMID 27466420 DOI: 10.1128/Jvi.00798-16  0.504
2016 Priyamvada L, Quicke KM, Hudson WH, Onlamoon N, Sewatanon J, Edupuganti S, Pattanapanyasat K, Chokephaibulkit K, Mulligan MJ, Wilson PC, Ahmed R, Suthar MS, Wrammert J. Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus. Proceedings of the National Academy of Sciences of the United States of America. PMID 27354515 DOI: 10.1073/Pnas.1607931113  0.398
2016 McElroy AK, Harmon JR, Flietstra TD, Campbell S, Mehta AK, Kraft CS, Lyon MG, Varkey JB, Ribner BS, Kratochvil CJ, Iwen PC, Smith PW, Ahmed R, Nichol ST, Spiropoulou CF. Kinetic Analysis of Biomarkers in a Cohort of US Patients With Ebola Virus Disease. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 27353663 DOI: 10.1093/Cid/Ciw334  0.301
2016 Zarnitsyna VI, Lavine J, Ellebedy A, Ahmed R, Antia R. Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza. Plos Pathogens. 12: e1005692. PMID 27336297 DOI: 10.1371/Journal.Ppat.1005692  0.385
2016 Priyamvada L, Cho A, Onlamoon N, Zheng NY, Huang M, Kovalenkov Y, Chokephaibulkit K, Angkasekwinai N, Pattanapanyasat K, Ahmed R, Wilson PC, Wrammert J. B cell responses during secondary dengue infection are dominated by highly cross-reactive, memory-derived plasmablasts. Journal of Virology. PMID 27030262 DOI: 10.1128/Jvi.03203-15  0.452
2016 Havenar-Daughton C, Lindqvist M, Heit A, Wu JE, Reiss SM, Kendric K, Bélanger S, Kasturi SP, Landais E, Akondy RS, McGuire HM, Bothwell M, Vagefi PA, Scully E, ... ... Ahmed R, et al. CXCL13 is a plasma biomarker of germinal center activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 26908875 DOI: 10.1073/Pnas.1520112113  0.424
2016 Quinn CP, Sabourin CL, Schiffer JM, Niemuth NA, Semenova VA, Li H, Rudge TL, Brys AM, Mittler RS, Ibegbu CC, Wrammert J, Ahmed R, Parker SD, Babcock J, Keitel W, et al. Humoral and Cell Mediated Immune Responses to Alternate Booster Schedules of Anthrax Vaccine Adsorbed in Humans. Clinical and Vaccine Immunology : Cvi. PMID 26865594 DOI: 10.1128/Cvi.00696-15  0.389
2016 Ahmed R. Abstract IA23: T cell memory and exhaustion Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-Ia23  0.526
2016 Hudson W, Kissick H, Hashimoto M, Ahmed R. Abstract B142: Long non-coding RNA expression during CD8+ T cell differentiation and exhaustion Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B142  0.546
2016 Kamphorst AO, Wieland A, Yang S, Nasti T, Zhang R, Barber DL, Konieczny BT, Koenig L, Yu K, Sica G, Owonikoko TK, Pillai R, Ramalingam SS, Sharpe AH, Freeman GJ, ... ... Ahmed R, et al. Abstract 4359: Rescue of exhausted CD8 T cells by PD-1 targeted therapies is CD28-dependent Cancer Research. 76: 4359-4359. DOI: 10.1158/1538-7445.Am2016-4359  0.559
2016 Tesini B, Halliley J, Ellebedy A, Kanagaiah P, Anderson C, Dediego M, Wang J, Zand M, Ahmed R, Krammer F, Treanor JJ, Topham D, Sangster M. Natural H3N2 influenza A Infection in Humans Expands Memory B Cells Specific for the Hemagglutinin Stalk Domain Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw172.1742  0.42
2015 Lee J, Ahn E, Kissick HT, Ahmed R. Reinvigorating Exhausted T Cells by Blockade of the PD-1 Pathway. Forum On Immunopathological Diseases and Therapeutics. 6: 7-17. PMID 28286692 DOI: 10.1615/Forumimmundisther.2015014188  0.4
2015 Nakaya HI, Hagan T, Duraisingham SS, Lee EK, Kwissa M, Rouphael N, Frasca D, Gersten M, Mehta AK, Gaujoux R, Li GM, Gupta S, Ahmed R, Mulligan MJ, Shen-Orr S, et al. Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures. Immunity. 43: 1186-98. PMID 26682988 DOI: 10.1016/J.Immuni.2015.11.012  0.339
2015 Andrews SF, Huang Y, Kaur K, Popova LI, Ho IY, Pauli NT, Henry Dunand CJ, Taylor WM, Lim S, Huang M, Qu X, Lee JH, Salgado-Ferrer M, Krammer F, Palese P, ... ... Ahmed R, et al. Immune history profoundly affects broadly protective B cell responses to influenza. Science Translational Medicine. 7: 316ra192. PMID 26631631 DOI: 10.1126/Scitranslmed.Aad0522  0.407
2015 Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J. The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. PMID 26410627 DOI: 10.1016/J.Immuni.2015.08.017  0.689
2015 Wu T, Wieland A, Lee J, Hale JS, Han JH, Xu X, Ahmed R. Cutting Edge: miR-17-92 Is Required for Both CD4 Th1 and T Follicular Helper Cell Responses during Viral Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26276869 DOI: 10.4049/Jimmunol.1500317  0.468
2015 Zarnitsyna VI, Ellebedy AH, Davis C, Jacob J, Ahmed R, Antia R. Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26194761 DOI: 10.1098/Rstb.2014.0248  0.361
2015 Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, Pertel T, Jin HT, Ahmed R, Anderson AC, Kuchroo VK. Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nature Communications. 6: 7657. PMID 26153760 DOI: 10.1038/Ncomms8657  0.356
2015 Wang TT, Maamary J, Tan GS, Bournazos S, Davis CW, Krammer F, Schlesinger SJ, Palese P, Ahmed R, Ravetch JV. Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy. Cell. 162: 160-9. PMID 26140596 DOI: 10.1016/J.Cell.2015.06.026  0.403
2015 Youngblood B, Hale JS, Ahmed R. Memory CD8 T cell transcriptional plasticity. F1000prime Reports. 7: 38. PMID 26097712 DOI: 10.12703/P7-38  0.602
2015 Kamphorst AO, Araki K, Ahmed R. Beyond adjuvants: immunomodulation strategies to enhance T cell immunity. Vaccine. 33: B21-8. PMID 26022562 DOI: 10.1016/J.Vaccine.2014.12.082  0.536
2015 Kaur K, Zheng NY, Smith K, Huang M, Li L, Pauli NT, Dunand CJ, Lee JH, Morrissey M, Wu Y, Joachims ML, Munroe ME, Lau D, Qu X, Krammer F, ... ... Ahmed R, et al. High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination. Plos One. 10: e0125618. PMID 25951191 DOI: 10.1371/Journal.Pone.0125618  0.372
2015 Bally AP, Lu P, Tang Y, Austin JW, Scharer CD, Ahmed R, Boss JM. NF-κB regulates PD-1 expression in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 194: 4545-54. PMID 25810391 DOI: 10.4049/Jimmunol.1402550  0.433
2015 McElroy AK, Akondy RS, Davis CW, Ellebedy AH, Mehta AK, Kraft CS, Lyon GM, Ribner BS, Varkey J, Sidney J, Sette A, Campbell S, Ströher U, Damon I, Nichol ST, ... ... Ahmed R, et al. Human Ebola virus infection results in substantial immune activation. Proceedings of the National Academy of Sciences of the United States of America. 112: 4719-24. PMID 25775592 DOI: 10.1073/Pnas.1502619112  0.608
2015 Akondy RS, Johnson PL, Nakaya HI, Edupuganti S, Mulligan MJ, Lawson B, Miller JD, Pulendran B, Antia R, Ahmed R. Initial viral load determines the magnitude of the human CD8 T cell response to yellow fever vaccination. Proceedings of the National Academy of Sciences of the United States of America. 112: 3050-5. PMID 25713354 DOI: 10.1073/Pnas.1500475112  0.584
2015 Hale JS, Ahmed R. Memory T follicular helper CD4 T cells. Frontiers in Immunology. 6: 16. PMID 25699040 DOI: 10.3389/Fimmu.2015.00016  0.608
2015 Henry Dunand CJ, Leon PE, Kaur K, Tan GS, Zheng NY, Andrews S, Huang M, Qu X, Huang Y, Salgado-Ferrer M, Ho IY, Taylor W, Hai R, Wrammert J, Ahmed R, et al. Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. The Journal of Clinical Investigation. 125: 1255-68. PMID 25689254 DOI: 10.1172/Jci74374  0.319
2015 Wieland A, Shashidharamurthy R, Kamphorst AO, Han JH, Aubert RD, Choudhury BP, Stowell SR, Lee J, Punkosdy GA, Shlomchik MJ, Selvaraj P, Ahmed R. Antibody effector functions mediated by Fcγ-receptors are compromised during persistent viral infection. Immunity. 42: 367-78. PMID 25680276 DOI: 10.1016/J.Immuni.2015.01.009  0.81
2015 Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, Pertel T, Jin HT, Ahmed R, Anderson AC, Kuchroo VK. An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nature Communications. 6: 6072. PMID 25614966 DOI: 10.1038/Ncomms7072  0.396
2015 Safeukui I, Gomez ND, Adelani AA, Burte F, Afolabi NK, Akondy R, Velazquez P, Holder A, Tewari R, Buffet P, Brown BJ, Shokunbi WA, Olaleye D, Sodeinde O, Kazura J, ... Ahmed R, et al. Malaria induces anemia through CD8+ T cell-dependent parasite clearance and erythrocyte removal in the spleen. Mbio. 6. PMID 25604792 DOI: 10.1128/Mbio.02493-14  0.451
2015 Penaloza-MacMaster P, Barber DL, Wherry EJ, Provine NM, Teigler JE, Parenteau L, Blackmore S, Borducchi EN, Larocca RA, Yates KB, Shen H, Haining WN, Sommerstein R, Pinschewer DD, Ahmed R, et al. Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection. Science (New York, N.Y.). 347: 278-82. PMID 25593185 DOI: 10.1126/Science.Aaa2148  0.731
2015 Mandl JN, Ahmed R, Barreiro LB, Daszak P, Epstein JH, Virgin HW, Feinberg MB. Reservoir host immune responses to emerging zoonotic viruses. Cell. 160: 20-35. PMID 25533784 DOI: 10.1016/J.Cell.2014.12.003  0.327
2015 Chiu C, Ellebedy AH, Wrammert J, Ahmed R. B cell responses to influenza infection and vaccination. Current Topics in Microbiology and Immunology. 386: 381-98. PMID 25193634 DOI: 10.1007/82_2014_425  0.4
2015 Blazar BR, O'Connor RS, Milone MC, Dustin ML, Riley JL, Vincent BG, Serody JS, Flynn RP, Paz K, Du J, Panoskaltsis-Mortari A, Jeffrey M, Ahmed R, Turka LAA, Freeman GJ, et al. Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease Blood. 126: SCI-8-SCI-8. DOI: 10.1182/Blood.V126.23.Sci-8.Sci-8  0.347
2015 Arthur CM, Weiland A, Sullivan HC, Ahmed R, Stowell SR. Clearance of Incompatible RBC Is Compromised during Persistent Viral Infection Blood. 126: 1149-1149. DOI: 10.1182/Blood.V126.23.1149.1149  0.405
2015 Kamphorst AO, Pillai RN, Yang S, Akondy R, Koenig L, Yu K, McCausland M, Sica G, Khuri FR, Owonikoko TK, Ramalingam SS, Ahmed R. Abstract 1317: Biomarker evaluation for PD-1 targeted therapies in non-small cell lung cancer (NSCLC) patients Cancer Research. 75: 1317-1317. DOI: 10.1158/1538-7445.Am2015-1317  0.413
2015 Kamphorst AO, Araki K, Ahmed R. Beyond adjuvants: Immunomodulation strategies to enhance T cell immunity Vaccine. 33: B21-B28. DOI: 10.1016/j.vaccine.2014.12.082  0.381
2014 Xu X, Araki K, Li S, Han JH, Ye L, Tan WG, Konieczny BT, Bruinsma MW, Martinez J, Pearce EL, Green DR, Jones DP, Virgin HW, Ahmed R. Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nature Immunology. 15: 1152-61. PMID 25362489 DOI: 10.1038/Ni.3025  0.626
2014 Linderman SL, Chambers BS, Zost SJ, Parkhouse K, Li Y, Herrmann C, Ellebedy AH, Carter DM, Andrews SF, Zheng NY, Huang M, Huang Y, Strauss D, Shaz BH, Hodinka RL, ... ... Ahmed R, et al. Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season. Proceedings of the National Academy of Sciences of the United States of America. 111: 15798-803. PMID 25331901 DOI: 10.1073/Pnas.1409171111  0.317
2014 Ellebedy AH, Krammer F, Li GM, Miller MS, Chiu C, Wrammert J, Chang CY, Davis CW, McCausland M, Elbein R, Edupuganti S, Spearman P, Andrews SF, Wilson PC, García-Sastre A, ... ... Ahmed R, et al. Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans. Proceedings of the National Academy of Sciences of the United States of America. 111: 13133-8. PMID 25157133 DOI: 10.1073/Pnas.1414070111  0.381
2014 Penaloza-MacMaster P, Kamphorst AO, Wieland A, Araki K, Iyer SS, West EE, O'Mara L, Yang S, Konieczny BT, Sharpe AH, Freeman GJ, Rudensky AY, Ahmed R. Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. The Journal of Experimental Medicine. 211: 1905-18. PMID 25113973 DOI: 10.1084/Jem.20132577  0.769
2014 Kwissa M, Nakaya HI, Onlamoon N, Wrammert J, Villinger F, Perng GC, Yoksan S, Pattanapanyasat K, Chokephaibulkit K, Ahmed R, Pulendran B. Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation. Cell Host & Microbe. 16: 115-27. PMID 24981333 DOI: 10.1016/J.Chom.2014.06.001  0.498
2014 Magadán JG, Altman MO, Ince WL, Hickman HD, Stevens J, Chevalier A, Baker D, Wilson PC, Ahmed R, Bennink JR, Yewdell JW. Biogenesis of influenza a virus hemagglutinin cross-protective stem epitopes. Plos Pathogens. 10: e1004204. PMID 24945804 DOI: 10.1371/Journal.Ppat.1004204  0.318
2014 Austin JW, Lu P, Majumder P, Ahmed R, Boss JM. STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells. Journal of Immunology (Baltimore, Md. : 1950). 192: 4876-86. PMID 24711622 DOI: 10.4049/Jimmunol.1302750  0.377
2014 Chiu C, McCausland M, Sidney J, Duh FM, Rouphael N, Mehta A, Mulligan M, Carrington M, Wieland A, Sullivan NL, Weinberg A, Levin MJ, Pulendran B, Peters B, Sette A, ... Ahmed R, et al. Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV. Plos Pathogens. 10: e1004008. PMID 24675761 DOI: 10.1371/Journal.Ppat.1004008  0.619
2014 Lu P, Youngblood BA, Austin JW, Mohammed AU, Butler R, Ahmed R, Boss JM. Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection. The Journal of Experimental Medicine. 211: 515-27. PMID 24590765 DOI: 10.1084/Jem.20130208  0.473
2014 Araki K, Youngblood B, Ahmed R. Programmed Cell Death 1-Directed Immunotherapy for Enhancing T-Cell Function. Cold Spring Harbor Symposia On Quantitative Biology. PMID 24415643 DOI: 10.1101/Sqb.78.019869  0.442
2014 Porichis F, Hart MG, Zupkosky J, Barblu L, Kwon DS, McMullen A, Brennan T, Ahmed R, Freeman GJ, Kavanagh DG, Kaufmann DE. Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions. Journal of Virology. 88: 2508-18. PMID 24352453 DOI: 10.1128/Jvi.02034-13  0.412
2014 Li S, Rouphael N, Duraisingham S, Romero-Steiner S, Presnell S, Davis C, Schmidt DS, Johnson SE, Milton A, Rajam G, Kasturi S, Carlone GM, Quinn C, Chaussabel D, Palucka AK, ... ... Ahmed R, et al. Molecular signatures of antibody responses derived from a systems biology study of five human vaccines. Nature Immunology. 15: 195-204. PMID 24336226 DOI: 10.1038/Ni.2789  0.35
2013 Araki K, Youngblood B, Ahmed R. Programmed cell death 1-directed immunotherapy for enhancing T-cell function. Cold Spring Harbor Symposia On Quantitative Biology. 78: 239-47. PMID 25028401 DOI: 10.1101/sqb.2013.78.019869  0.331
2013 Horne-Debets JM, Faleiro R, Karunarathne DS, Liu XQ, Lineburg KE, Poh CM, Grotenbreg GM, Hill GR, MacDonald KP, Good MF, Renia L, Ahmed R, Sharpe AH, Wykes MN. PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria. Cell Reports. 5: 1204-13. PMID 24316071 DOI: 10.1016/J.Celrep.2013.11.002  0.538
2013 Iyer SS, Latner DR, Zilliox MJ, McCausland M, Akondy RS, Penaloza-Macmaster P, Hale JS, Ye L, Mohammed AU, Yamaguchi T, Sakaguchi S, Amara RR, Ahmed R. Identification of novel markers for mouse CD4(+) T follicular helper cells. European Journal of Immunology. 43: 3219-32. PMID 24030473 DOI: 10.1002/Eji.201343469  0.577
2013 Saha A, Aoyama K, Taylor PA, Koehn BH, Veenstra RG, Panoskaltsis-Mortari A, Munn DH, Murphy WJ, Azuma M, Yagita H, Fife BT, Sayegh MH, Najafian N, Socie G, Ahmed R, et al. Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality. Blood. 122: 3062-73. PMID 24030385 DOI: 10.1182/Blood-2013-05-500801  0.303
2013 Kamphorst AO, Ahmed R. CD4 T-cell immunotherapy for chronic viral infections and cancer. Immunotherapy. 5: 975-87. PMID 23998732 DOI: 10.2217/Imt.13.91  0.607
2013 Fuller MJ, Callendret B, Zhu B, Freeman GJ, Hasselschwert DL, Satterfield W, Sharpe AH, Dustin LB, Rice CM, Grakoui A, Ahmed R, Walker CM. Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1). Proceedings of the National Academy of Sciences of the United States of America. 110: 15001-6. PMID 23980172 DOI: 10.1073/Pnas.1312772110  0.44
2013 Scharer CD, Barwick BG, Youngblood BA, Ahmed R, Boss JM. Global DNA methylation remodeling accompanies CD8 T cell effector function. Journal of Immunology (Baltimore, Md. : 1950). 191: 3419-29. PMID 23956425 DOI: 10.4049/Jimmunol.1301395  0.514
2013 Li Y, Myers JL, Bostick DL, Sullivan CB, Madara J, Linderman SL, Liu Q, Carter DM, Wrammert J, Esposito S, Principi N, Plotkin JB, Ross TM, Ahmed R, Wilson PC, et al. Immune history shapes specificity of pandemic H1N1 influenza antibody responses. The Journal of Experimental Medicine. 210: 1493-500. PMID 23857983 DOI: 10.1084/Jem.20130212  0.34
2013 Ahmed R, Burton DR. Viral vaccines: past successes and future challenges. Current Opinion in Virology. 3: 307-8. PMID 23809262 DOI: 10.1016/J.Coviro.2013.06.007  0.423
2013 Youngblood B, Noto A, Porichis F, Akondy RS, Ndhlovu ZM, Austin JW, Bordi R, Procopio FA, Miura T, Allen TM, Sidney J, Sette A, Walker BD, Ahmed R, Boss JM, et al. Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 540-4. PMID 23772031 DOI: 10.4049/Jimmunol.1203161  0.483
2013 Bodewes R, Geelhoed-Mieras MM, Wrammert J, Ahmed R, Wilson PC, Fouchier RA, Osterhaus AD, Rimmelzwaan GF. In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza a virus nucleoprotein. Clinical and Vaccine Immunology : Cvi. 20: 1333-7. PMID 23761662 DOI: 10.1128/Cvi.00339-13  0.451
2013 Koff WC, Burton DR, Johnson PR, Walker BD, King CR, Nabel GJ, Ahmed R, Bhan MK, Plotkin SA. Accelerating next-generation vaccine development for global disease prevention. Science (New York, N.Y.). 340: 1232910. PMID 23723240 DOI: 10.1126/Science.1232910  0.302
2013 West EE, Jin HT, Rasheed AU, Penaloza-Macmaster P, Ha SJ, Tan WG, Youngblood B, Freeman GJ, Smith KA, Ahmed R. PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells. The Journal of Clinical Investigation. 123: 2604-15. PMID 23676462 DOI: 10.1172/Jci67008  0.715
2013 Rasheed MA, Latner DR, Aubert RD, Gourley T, Spolski R, Davis CW, Langley WA, Ha SJ, Ye L, Sarkar S, Kalia V, Konieczny BT, Leonard WJ, Ahmed R. Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells. Journal of Virology. 87: 7737-46. PMID 23637417 DOI: 10.1128/Jvi.00063-13  0.837
2013 Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman GJ, Krogsgaard M, Riley JL. Strength of PD-1 signaling differentially affects T-cell effector functions. Proceedings of the National Academy of Sciences of the United States of America. 110: E2480-9. PMID 23610399 DOI: 10.1073/Pnas.1305394110  0.416
2013 Lau LL, Jamieson BD, Somasundaram T, Ahmed R. Pillars Article: Cytotoxic T-cell Memory without Antigen. Nature. 1994. 369: 648-652. Journal of Immunology (Baltimore, Md. : 1950). 190: 4445-9. PMID 23606721  0.416
2013 Hale JS, Youngblood B, Latner DR, Mohammed AU, Ye L, Akondy RS, Wu T, Iyer SS, Ahmed R. Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection. Immunity. 38: 805-17. PMID 23583644 DOI: 10.1016/J.Immuni.2013.02.020  0.656
2013 Kamphorst AO, Ahmed R. Manipulating the PD-1 pathway to improve immunity. Current Opinion in Immunology. 25: 381-8. PMID 23582509 DOI: 10.1016/J.Coi.2013.03.003  0.403
2013 Araki K, Ahmed R. AMPK: a metabolic switch for CD8+ T-cell memory. European Journal of Immunology. 43: 878-81. PMID 23504580 DOI: 10.1002/Eji.201343483  0.546
2013 Chiu C, Wrammert J, Li GM, McCausland M, Wilson PC, Ahmed R. Cross-reactive humoral responses to influenza and their implications for a universal vaccine. Annals of the New York Academy of Sciences. 1283: 13-21. PMID 23405860 DOI: 10.1111/Nyas.12012  0.353
2013 Youngblood B, Hale JS, Ahmed R. T-cell memory differentiation: insights from transcriptional signatures and epigenetics. Immunology. 139: 277-84. PMID 23347146 DOI: 10.1111/Imm.12074  0.57
2013 Brooke CB, Ince WL, Wrammert J, Ahmed R, Wilson PC, Bennink JR, Yewdell JW. Most influenza a virions fail to express at least one essential viral protein. Journal of Virology. 87: 3155-62. PMID 23283949 DOI: 10.1128/Jvi.02284-12  0.408
2013 Edupuganti S, Eidex RB, Keyserling H, Akondy RS, Lanciotti R, Orenstein W, del Rio C, Pan Y, Querec T, Lipman H, Barrett A, Ahmed R, Teuwen D, Cetron M, Mulligan MJ, et al. A randomized, double-blind, controlled trial of the 17D yellow fever virus vaccine given in combination with immune globulin or placebo: comparative viremia and immunogenicity. The American Journal of Tropical Medicine and Hygiene. 88: 172-7. PMID 23208880 DOI: 10.4269/Ajtmh.2012.12-0179  0.382
2013 Tan WG, Jin HT, West EE, Penaloza-MacMaster P, Wieland A, Zilliox MJ, McElrath MJ, Barouch DH, Ahmed R. Comparative analysis of simian immunodeficiency virus gag-specific effector and memory CD8+ T cells induced by different adenovirus vectors. Journal of Virology. 87: 1359-72. PMID 23175355 DOI: 10.1128/Jvi.02055-12  0.731
2013 Hossain MS, El-Najjar VF, Jaye DL, Ahmed R, Waller EK. Expression Of PD-L1 Is Required To Control Acute GvHD In Allo-HSCT Recipients Blood. 122: 2008-2008. DOI: 10.1182/Blood.V122.21.2008.2008  0.324
2012 Xu X, Ye L, Araki K, Ahmed R. mTOR, linking metabolism and immunity. Seminars in Immunology. 24: 429-35. PMID 23352227 DOI: 10.1016/J.Smim.2012.12.005  0.496
2012 Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008  0.34
2012 Quinn CP, Sabourin CL, Niemuth NA, Li H, Semenova VA, Rudge TL, Mayfield HJ, Schiffer J, Mittler RS, Ibegbu CC, Wrammert J, Ahmed R, Brys AM, Hunt RE, Levesque D, et al. A three-dose intramuscular injection schedule of anthrax vaccine adsorbed generates sustained humoral and cellular immune responses to protective antigen and provides long-term protection against inhalation anthrax in rhesus macaques. Clinical and Vaccine Immunology : Cvi. 19: 1730-45. PMID 22933399 DOI: 10.1128/Cvi.00324-12  0.433
2012 Yoon HS, Scharer CD, Majumder P, Davis CW, Butler R, Zinzow-Kramer W, Skountzou I, Koutsonanos DG, Ahmed R, Boss JM. ZBTB32 is an early repressor of the CIITA and MHC class II gene expression during B cell differentiation to plasma cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 2393-403. PMID 22851713 DOI: 10.4049/Jimmunol.1103371  0.344
2012 Feinberg MB, Ahmed R. Born this way? Understanding the immunological basis of effective HIV control. Nature Immunology. 13: 632-4. PMID 22713821 DOI: 10.1038/Ni.2351  0.323
2012 Wu T, Wieland A, Araki K, Davis CW, Ye L, Hale JS, Ahmed R. Temporal expression of microRNA cluster miR-17-92 regulates effector and memory CD8+ T-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 109: 9965-70. PMID 22665768 DOI: 10.1073/Pnas.1207327109  0.511
2012 O'Donnell CD, Vogel L, Wright A, Das SR, Wrammert J, Li GM, McCausland M, Zheng NY, Yewdell JW, Ahmed R, Wilson PC, Subbarao K. Antibody pressure by a human monoclonal antibody targeting the 2009 pandemic H1N1 virus hemagglutinin drives the emergence of a virus with increased virulence in mice. Mbio. 3. PMID 22647789 DOI: 10.1128/Mbio.00120-12  0.355
2012 Li GM, Chiu C, Wrammert J, McCausland M, Andrews SF, Zheng NY, Lee JH, Huang M, Qu X, Edupuganti S, Mulligan M, Das SR, Yewdell JW, Mehta AK, Wilson PC, ... Ahmed R, et al. Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 9047-52. PMID 22615367 DOI: 10.1073/Pnas.1118979109  0.399
2012 Ellebedy AH, Ahmed R. Re-engaging cross-reactive memory B cells: the influenza puzzle. Frontiers in Immunology. 3: 53. PMID 22566934 DOI: 10.3389/Fimmu.2012.00053  0.431
2012 Lin JX, Li P, Liu D, Jin HT, He J, Ata Ur Rasheed M, Rochman Y, Wang L, Cui K, Liu C, Kelsall BL, Ahmed R, Leonard WJ. Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. Immunity. 36: 586-99. PMID 22520852 DOI: 10.1016/J.Immuni.2012.02.017  0.529
2012 Johnson PL, Kochin BF, Ahmed R, Antia R. How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens? Proceedings. Biological Sciences / the Royal Society. 279: 2777-85. PMID 22438498 DOI: 10.1098/Rspb.2012.0005  0.39
2012 Wrammert J, Onlamoon N, Akondy RS, Perng GC, Polsrila K, Chandele A, Kwissa M, Pulendran B, Wilson PC, Wittawatmongkol O, Yoksan S, Angkasekwinai N, Pattanapanyasat K, Chokephaibulkit K, Ahmed R. Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans. Journal of Virology. 86: 2911-8. PMID 22238318 DOI: 10.1128/Jvi.06075-11  0.434
2012 Zinzow-Kramer WM, Long AB, Youngblood BA, Rosenthal KM, Butler R, Mohammed AU, Skountzou I, Ahmed R, Evavold BD, Boss JM. CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments. Genes and Immunity. 13: 299-310. PMID 22218223 DOI: 10.1038/Gene.2011.86  0.39
2012 Youngblood B, Wherry EJ, Ahmed R. Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells. Current Opinion in Hiv and Aids. 7: 50-7. PMID 22134341 DOI: 10.1097/Coh.0B013E32834Ddcf2  0.711
2012 Iyer SS, Chatraw JH, Tan WG, Wherry EJ, Becker TC, Ahmed R, Kapasi ZF. Protein energy malnutrition impairs homeostatic proliferation of memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 77-84. PMID 22116826 DOI: 10.4049/Jimmunol.1004027  0.78
2012 Kwa S, Sadagopal S, Hong J, Gangadhara S, Basu R, Lai L, Iyer S, Araki K, Earl PL, Wyatt L, Villinger F, Moss B, Ahmed R, Amara R. CD40L adjuvant for DNA/MVA vaccine: enhanced protection from acquisition of neutralization sensitive & neutralization resistant mucosal SIV infections Retrovirology. 9: 365. DOI: 10.1186/1742-4690-9-S2-P365  0.334
2012 Penaloza P, Borducchi E, McNally A, Simmons N, Teigler J, Provine N, Tan W, Ahmed R, Barouch DH. Different memory T cell phenotypes are elicited by Ad5 and rare adenoviruses Retrovirology. 9: 246. DOI: 10.1186/1742-4690-9-S2-P246  0.514
2011 Aubert RD, Kamphorst AO, Sarkar S, Vezys V, Ha SJ, Barber DL, Ye L, Sharpe AH, Freeman GJ, Ahmed R. Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. 108: 21182-7. PMID 22160724 DOI: 10.1073/Pnas.1118450109  0.852
2011 Ahmed R, Pulendran B. Learning vaccinology from viral infections. The Journal of Experimental Medicine. 208: 2347-9. PMID 22110181 DOI: 10.1084/Jem.20112321  0.311
2011 Walker BD, Ahmed R, Plotkin S. Moving ahead an HIV vaccine: use both arms to beat HIV. Nature Medicine. 17: 1194-5. PMID 21988996 DOI: 10.1038/Nm.2529  0.374
2011 Youngblood B, Oestreich KJ, Ha SJ, Duraiswamy J, Akondy RS, West EE, Wei Z, Lu P, Austin JW, Riley JL, Boss JM, Ahmed R. Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity. 35: 400-12. PMID 21943489 DOI: 10.1016/J.Immuni.2011.06.015  0.75
2011 Araki K, Ellebedy AH, Ahmed R. TOR in the immune system. Current Opinion in Cell Biology. 23: 707-15. PMID 21925855 DOI: 10.1016/J.Ceb.2011.08.006  0.504
2011 Kotturi MF, Swann JA, Peters B, Arlehamn CL, Sidney J, Kolla RV, James EA, Akondy RS, Ahmed R, Kwok WW, Buchmeier MJ, Sette A. Human CD8⁺ and CD4⁺ T cell memory to lymphocytic choriomeningitis virus infection. Journal of Virology. 85: 11770-80. PMID 21900169 DOI: 10.1128/Jvi.05477-11  0.632
2011 West EE, Youngblood B, Tan WG, Jin HT, Araki K, Alexe G, Konieczny BT, Calpe S, Freeman GJ, Terhorst C, Haining WN, Ahmed R. Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load. Immunity. 35: 285-98. PMID 21856186 DOI: 10.1016/J.Immuni.2011.05.017  0.791
2011 De Rosa SC, Thomas EP, Bui J, Huang Y, deCamp A, Morgan C, Kalams SA, Tomaras GD, Akondy R, Ahmed R, Lau CY, Graham BS, Nabel GJ, McElrath MJ. HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable. Journal of Immunology (Baltimore, Md. : 1950). 187: 3391-401. PMID 21844392 DOI: 10.4049/Jimmunol.1101421  0.52
2011 Nakaya HI, Wrammert J, Lee EK, Racioppi L, Marie-Kunze S, Haining WN, Means AR, Kasturi SP, Khan N, Li GM, McCausland M, Kanchan V, Kokko KE, Li S, Elbein R, ... ... Ahmed R, et al. Systems biology of vaccination for seasonal influenza in humans. Nature Immunology. 12: 786-95. PMID 21743478 DOI: 10.1038/Ni.2067  0.331
2011 Vezys V, Penaloza-MacMaster P, Barber DL, Ha SJ, Konieczny B, Freeman GJ, Mittler RS, Ahmed R. 4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection. Journal of Immunology (Baltimore, Md. : 1950). 187: 1634-42. PMID 21742975 DOI: 10.4049/Jimmunol.1100077  0.501
2011 Pulendran B, Ahmed R. Immunological mechanisms of vaccination. Nature Immunology. 12: 509-17. PMID 21739679 DOI: 10.1038/Ni.2039  0.302
2011 Mandl JN, Akondy R, Lawson B, Kozyr N, Staprans SI, Ahmed R, Feinberg MB. Distinctive TLR7 signaling, type I IFN production, and attenuated innate and adaptive immune responses to yellow fever virus in a primate reservoir host. Journal of Immunology (Baltimore, Md. : 1950). 186: 6406-16. PMID 21515797 DOI: 10.4049/Jimmunol.1001191  0.428
2011 Penaloza-MacMaster P, Ur Rasheed A, Iyer SS, Yagita H, Blazar BR, Ahmed R. Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of mice. Journal of Virology. 85: 6168-74. PMID 21507976 DOI: 10.1128/Jvi.02205-10  0.614
2011 Johnson PL, Kochin BF, McAfee MS, Stromnes IM, Regoes RR, Ahmed R, Blattman JN, Antia R. Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections. Journal of Virology. 85: 5565-70. PMID 21411537 DOI: 10.1128/Jvi.00166-11  0.851
2011 Duraiswamy J, Ibegbu CC, Masopust D, Miller JD, Araki K, Doho GH, Tata P, Gupta S, Zilliox MJ, Nakaya HI, Pulendran B, Haining WN, Freeman GJ, Ahmed R. Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults. Journal of Immunology (Baltimore, Md. : 1950). 186: 4200-12. PMID 21383243 DOI: 10.4049/Jimmunol.1001783  0.555
2011 Turner AP, Shaffer VO, Araki K, Martens C, Turner PL, Gangappa S, Ford ML, Ahmed R, Kirk AD, Larsen CP. Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 613-8. PMID 21342450 DOI: 10.1111/J.1600-6143.2010.03407.X  0.567
2011 Punkosdy GA, Blain M, Glass DD, Lozano MM, O'Mara L, Dudley JP, Ahmed R, Shevach EM. Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens. Proceedings of the National Academy of Sciences of the United States of America. 108: 3677-82. PMID 21321220 DOI: 10.1073/Pnas.1100213108  0.537
2011 Allen SJ, Hamrah P, Gate D, Mott KR, Mantopoulos D, Zheng L, Town T, Jones C, von Andrian UH, Freeman GJ, Sharpe AH, BenMohamed L, Ahmed R, Wechsler SL, Ghiasi H. The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. Journal of Virology. 85: 4184-97. PMID 21307196 DOI: 10.1128/Jvi.02290-10  0.543
2011 Ahmed R, Akondy RS. Insights into human CD8(+) T-cell memory using the yellow fever and smallpox vaccines. Immunology and Cell Biology. 89: 340-5. PMID 21301482 DOI: 10.1038/Icb.2010.155  0.615
2011 Wrammert J, Koutsonanos D, Li GM, Edupuganti S, Sui J, Morrissey M, McCausland M, Skountzou I, Hornig M, Lipkin WI, Mehta A, Razavi B, Del Rio C, Zheng NY, Lee JH, ... ... Ahmed R, et al. Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. The Journal of Experimental Medicine. 208: 181-93. PMID 21220454 DOI: 10.1084/Jem.20101352  0.369
2011 Jin HT, Ahmed R, Okazaki T. Role of PD-1 in regulating T-cell immunity. Current Topics in Microbiology and Immunology. 350: 17-37. PMID 21061197 DOI: 10.1007/82_2010_116  0.334
2011 Chandele A, Mukerjee P, Das G, Ahmed R, Chauhan VS. Phenotypic and functional profiling of malaria-induced CD8 and CD4 T cells during blood-stage infection with Plasmodium yoelii. Immunology. 132: 273-86. PMID 21039472 DOI: 10.1111/J.1365-2567.2010.03363.X  0.602
2010 Sallusto F, Lanzavecchia A, Araki K, Ahmed R. From vaccines to memory and back. Immunity. 33: 451-63. PMID 21029957 DOI: 10.1016/J.Immuni.2010.10.008  0.462
2010 Araki K, Gangappa S, Dillehay DL, Rouse BT, Larsen CP, Ahmed R. Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation. The Journal of Experimental Medicine. 207: 2355-67. PMID 20921283 DOI: 10.1084/Jem.20100124  0.515
2010 Kalia V, Sarkar S, Ahmed R. CD8 T-cell memory differentiation during acute and chronic viral infections. Advances in Experimental Medicine and Biology. 684: 79-95. PMID 20795542 DOI: 10.1007/978-1-4419-6451-9_7  0.628
2010 Choo DK, Murali-Krishna K, Anita R, Ahmed R. Homeostatic turnover of virus-specific memory CD8 T cells occurs stochastically and is independent of CD4 T cell help. Journal of Immunology (Baltimore, Md. : 1950). 185: 3436-44. PMID 20733203 DOI: 10.4049/Jimmunol.1001421  0.818
2010 Youngblood B, Davis CW, Ahmed R. Making memories that last a lifetime: heritable functions of self-renewing memory CD8 T cells. International Immunology. 22: 797-803. PMID 20732857 DOI: 10.1093/Intimm/Dxq437  0.596
2010 Jin HT, Anderson AC, Tan WG, West EE, Ha SJ, Araki K, Freeman GJ, Kuchroo VK, Ahmed R. Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. 107: 14733-8. PMID 20679213 DOI: 10.1073/Pnas.1009731107  0.778
2010 Mueller SN, Langley WA, Li G, García-Sastre A, Webby RJ, Ahmed R. Qualitatively different memory CD8+ T cells are generated after lymphocytic choriomeningitis virus and influenza virus infections. Journal of Immunology (Baltimore, Md. : 1950). 185: 2182-90. PMID 20639484 DOI: 10.4049/Jimmunol.1001142  0.848
2010 Ferrer IR, Wagener ME, Robertson JM, Turner AP, Araki K, Ahmed R, Kirk AD, Larsen CP, Ford ML. Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 2004-8. PMID 20631309 DOI: 10.4049/Jimmunol.1001176  0.484
2010 Mueller SN, Vanguri VK, Ha SJ, West EE, Keir ME, Glickman JN, Sharpe AH, Ahmed R. PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. The Journal of Clinical Investigation. 120: 2508-15. PMID 20551512 DOI: 10.1172/Jci40040  0.703
2010 Araki K, Youngblood B, Ahmed R. The role of mTOR in memory CD8 T-cell differentiation. Immunological Reviews. 235: 234-43. PMID 20536567 DOI: 10.1111/J.0105-2896.2010.00898.X  0.613
2010 Kim PS, Ahmed R. Features of responding T cells in cancer and chronic infection. Current Opinion in Immunology. 22: 223-30. PMID 20207527 DOI: 10.1016/J.Coi.2010.02.005  0.495
2010 Masopust D, Choo D, Vezys V, Wherry EJ, Duraiswamy J, Akondy R, Wang J, Casey KA, Barber DL, Kawamura KS, Fraser KA, Webby RJ, Brinkmann V, Butcher EC, Newell KA, ... Ahmed R, et al. Dynamic T cell migration program provides resident memory within intestinal epithelium. The Journal of Experimental Medicine. 207: 553-64. PMID 20156972 DOI: 10.1084/Jem.20090858  0.801
2010 Kalia V, Sarkar S, Subramaniam S, Haining WN, Smith KA, Ahmed R. Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity. 32: 91-103. PMID 20096608 DOI: 10.1016/J.Immuni.2009.11.010  0.544
2010 Mueller SN, Langley WA, Carnero E, García-Sastre A, Ahmed R. Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses. Journal of Virology. 84: 1847-55. PMID 19939929 DOI: 10.1128/Jvi.01317-09  0.836
2010 Ahmed R, Bevan MJ, Feau S, Wolkers M, Borst J, Schumacher T, Yagita H, Schoenberger S, Sallusto F, Radbruch A, Hauser A, Tokoyoda K, Shlomchik M, Good-Jacobson K, Khalil A. T and B cell memory (SY3-4) Chairpersons: Toshitada Takemori, Federica Sallusto International Immunology. 22. DOI: 10.1093/Intimm/Dxq287  0.481
2010 Campbell IL, Manders P, Lim S, Terry RL, Getts MT, Getts DR, King NJC, Hofer MJ, Araki K, Gangappa S, Rouse BT, Larsen CP, Ahmed R, Shimizu VS, Diego RPd, et al. Immunity to virus infection (excluding retroviruses) 1 (WS-025a) Chairpersons: Yusuke Yanagi, Nicholas King International Immunology. 22. DOI: 10.1093/Intimm/Dxq181  0.352
2009 Akondy RS, Monson ND, Miller JD, Edupuganti S, Teuwen D, Wu H, Quyyumi F, Garg S, Altman JD, Del Rio C, Keyserling HL, Ploss A, Rice CM, Orenstein WA, Mulligan MJ, ... Ahmed R, et al. The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. Journal of Immunology (Baltimore, Md. : 1950). 183: 7919-30. PMID 19933869 DOI: 10.4049/Jimmunol.0803903  0.64
2009 Penaloza-MacMaster P, Masopust D, Ahmed R. T-cell reconstitution without T-cell immunopathology in two models of T-cell-mediated tissue destruction. Immunology. 128: 164-71. PMID 19740373 DOI: 10.1111/J.1365-2567.2009.03080.X  0.578
2009 Ahmed R, Bevan MJ, Reiner SL, Fearon DT. The precursors of memory: models and controversies. Nature Reviews. Immunology. 9: 662-8. PMID 19680250 DOI: 10.1038/Nri2619  0.523
2009 Virgin HW, Wherry EJ, Ahmed R. Redefining chronic viral infection. Cell. 138: 30-50. PMID 19596234 DOI: 10.1016/J.Cell.2009.06.036  0.565
2009 Araki K, Turner AP, Shaffer VO, Gangappa S, Keller SA, Bachmann MF, Larsen CP, Ahmed R. mTOR regulates memory CD8 T-cell differentiation. Nature. 460: 108-12. PMID 19543266 DOI: 10.1038/Nature08155  0.615
2009 Mueller SN, Ahmed R. High antigen levels are the cause of T cell exhaustion during chronic viral infection Proceedings of the National Academy of Sciences of the United States of America. 106: 8623-8628. PMID 19433785 DOI: 10.1073/Pnas.0809818106  0.609
2009 Li Q, Skinner PJ, Ha SJ, Duan L, Mattila TL, Hage A, White C, Barber DL, O'Mara L, Southern PJ, Reilly CS, Carlis JV, Miller CJ, Ahmed R, Haase AT. Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science (New York, N.Y.). 323: 1726-9. PMID 19325114 DOI: 10.1126/Science.1168676  0.429
2009 Smith K, Garman L, Wrammert J, Zheng NY, Capra JD, Ahmed R, Wilson PC. Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen Nature Protocols. 4: 372-384. PMID 19247287 DOI: 10.1038/Nprot.2009.3  0.358
2009 Blattman JN, Wherry EJ, Ha SJ, van der Most RG, Ahmed R. Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection. Journal of Virology. 83: 4386-94. PMID 19211743 DOI: 10.1128/Jvi.02524-08  0.841
2009 Whitmire JK, Asano MS, Kaech SM, Sarkar S, Hannum LG, Shlomchik MJ, Ahmed R. Requirement of B cells for generating CD4+ T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 182: 1868-76. PMID 19201839 DOI: 10.4049/Jimmunol.0802501  0.742
2009 Velu V, Titanji K, Zhu B, Husain S, Pladevega A, Lai L, Vanderford TH, Chennareddi L, Silvestri G, Freeman GJ, Ahmed R, Amara RR. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature. 458: 206-10. PMID 19078956 DOI: 10.1038/Nature07662  0.497
2009 Wrammert J, Miller J, Akondy R, Ahmed R. Human Immune Memory to Yellow Fever and Smallpox Vaccination Journal of Clinical Immunology. 29: 151-157. PMID 19052852 DOI: 10.1007/S10875-008-9267-3  0.45
2009 Querec TD, Akondy RS, Lee EK, Cao W, Nakaya HI, Teuwen D, Pirani A, Gernert K, Deng J, Marzolf B, Kennedy K, Wu H, Bennouna S, Oluoch H, Miller J, ... ... Ahmed R, et al. Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nature Immunology. 10: 116-25. PMID 19029902 DOI: 10.1038/Ni.1688  0.377
2009 Vezys V, Yates A, Casey KA, Lanier G, Ahmed R, Antia R, Masopust D. Memory CD8 T-cell compartment grows in size with immunological experience. Nature. 457: 196-9. PMID 19005468 DOI: 10.1038/Nature07486  0.625
2009 Doria-Rose NA, Klein RM, Manion MM, O'Dell S, Phogat A, Chakrabarti B, Hallahan CW, Migueles SA, Wrammert J, Ahmed R, Nason M, Wyatt RT, Mascola JR, Connors M. Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. Journal of Virology. 83: 188-99. PMID 18922865 DOI: 10.1128/Jvi.01583-08  0.403
2009 Vezys V, Yates A, Casey KA, Lanier G, Ahmed R, Antia R, Masopust D. Vezys et al. reply Nature. 459. DOI: 10.1038/Nature08092  0.618
2008 Wrammert J, Ahmed R. Maintenance of serological memory. Biological Chemistry. 389: 537-539. PMID 18953719 DOI: 10.1515/Bc.2008.066  0.399
2008 Oestreich KJ, Yoon H, Ahmed R, Boss JM. NFATc1 regulates PD-1 expression upon T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 181: 4832-9. PMID 18802087 DOI: 10.4049/Jimmunol.181.7.4832  0.447
2008 Mueller SN, Ahmed R. Lymphoid stroma in the initiation and control of immune responses. Immunological Reviews. 224: 284-294. PMID 18759934 DOI: 10.1111/J.1600-065X.2008.00657.X  0.408
2008 Jayasekera CR, Harris JB, Bhuiyan S, Chowdhury F, Khan AI, Faruque AS, Larocque RC, Ryan ET, Ahmed R, Qadri F, Calderwood SB. Cholera toxin-specific memory B cell responses are induced in patients with dehydrating diarrhea caused by Vibrio cholerae O1. The Journal of Infectious Diseases. 198: 1055-61. PMID 18729782 DOI: 10.1086/591500  0.447
2008 Haining WN, Ebert BL, Subrmanian A, Wherry EJ, Eichbaum Q, Evans JW, Mak R, Rivoli S, Pretz J, Angelosanto J, Smutko JS, Walker BD, Kaech SM, Ahmed R, Nadler LM, et al. Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 1859-68. PMID 18641323 DOI: 10.4049/Jimmunol.181.3.1859  0.779
2008 Ha SJ, West EE, Araki K, Smith KA, Ahmed R. Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections. Immunological Reviews. 223: 317-33. PMID 18613845 DOI: 10.1111/J.1600-065X.2008.00638.X  0.741
2008 Miller JD, van der Most RG, Akondy RS, Glidewell JT, Albott S, Masopust D, Murali-Krishna K, Mahar PL, Edupuganti S, Lalor S, Germon S, Del Rio C, Mulligan MJ, Staprans SI, Altman JD, ... ... Ahmed R, et al. Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines. Immunity. 28: 710-22. PMID 18468462 DOI: 10.1016/J.Immuni.2008.02.020  0.624
2008 Wrammert J, Smith K, Miller J, Langley WA, Kokko K, Larsen C, Zheng NY, Mays I, Garman L, Helms C, James J, Air GM, Capra JD, Ahmed R, Wilson PC. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature. 453: 667-71. PMID 18449194 DOI: 10.1038/Nature06890  0.771
2008 Chatraw JH, Wherry EJ, Ahmed R, Kapasi ZF. Diminished primary CD8 T cell response to viral infection during protein energy malnutrition in mice is due to changes in microenvironment and low numbers of viral-specific CD8 T cell precursors. The Journal of Nutrition. 138: 806-12. PMID 18356339 DOI: 10.1093/Jn/138.4.806  0.689
2008 Ha SJ, Mueller SN, Wherry EJ, Barber DL, Aubert RD, Sharpe AH, Freeman GJ, Ahmed R. Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. The Journal of Experimental Medicine. 205: 543-55. PMID 18332181 DOI: 10.1084/Jem.20071949  0.846
2008 Sarkar S, Kalia V, Haining WN, Konieczny BT, Subramaniam S, Ahmed R. Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. The Journal of Experimental Medicine. 205: 625-40. PMID 18316415 DOI: 10.1084/Jem.20071641  0.536
2008 Gangappa S, Kokko KE, Carlson LM, Gourley T, Newell KA, Pearson TC, Ahmed R, Larsen CP. Immune responsiveness and protective immunity after transplantation. Transplant International : Official Journal of the European Society For Organ Transplantation. 21: 293-303. PMID 18225995 DOI: 10.1111/J.1432-2277.2007.00631.X  0.338
2008 Kalia V, Sarkar S, Ahmed R. Fine-tuning CD4+ central memory T cell heterogeneity by strength of stimulation. European Journal of Immunology. 38: 15-9. PMID 18157815 DOI: 10.1002/Eji.200738044  0.566
2008 Qu D, Lanier G, Yuan ZH, Wen YM, Howard CR, Ahmed R. Localization of CD8+ cells specific for hepatitis B virus surface protein in the liver of immunized mice. Journal of Medical Virology. 80: 225-32. PMID 18098130 DOI: 10.1002/Jmv.21039  0.584
2008 Ahmed R. Immunological Memory: Remembering Our Pathogens. Blood. 112. DOI: 10.1182/Blood.V112.11.Sci-23.Sci-23  0.577
2007 Yates A, Graw F, Barber DL, Ahmed R, Regoes RR, Antia R. Revisiting estimates of CTL killing rates in vivo. Plos One. 2: e1301. PMID 18074025 DOI: 10.1371/Journal.Pone.0001301  0.395
2007 Aneja R, Kalia V, Ahmed R, Joshi HC. Nonimmunosuppressive chemotherapy: EM011-treated mice mount normal T-cell responses to an acute lymphocytic choriomeningitis virus infection. Molecular Cancer Therapeutics. 6: 2891-9. PMID 18025274 DOI: 10.1158/1535-7163.Mct-07-0359  0.572
2007 Sarkar S, Teichgräber V, Kalia V, Polley A, Masopust D, Harrington LE, Ahmed R, Wherry EJ. Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 179: 6704-14. PMID 17982060 DOI: 10.4049/Jimmunol.179.10.6704  0.812
2007 Masopust D, Vezys V, Wherry EJ, Ahmed R. A brief history of CD8 T cells. European Journal of Immunology. 37: S103-10. PMID 17972353 DOI: 10.1002/Eji.200737584  0.736
2007 Ahmed R, Oldstone MB, Palese P. Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic. Nature Immunology. 8: 1188-93. PMID 17952044 DOI: 10.1038/Ni1530  0.485
2007 Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, Subramaniam S, Blattman JN, Barber DL, Ahmed R. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity. 27: 670-84. PMID 17950003 DOI: 10.1016/J.Immuni.2007.09.006  0.861
2007 Constantin CM, Masopust D, Gourley T, Grayson J, Strickland OL, Ahmed R, Bonney EA. Normal establishment of virus-specific memory CD8 T cell pool following primary infection during pregnancy. Journal of Immunology (Baltimore, Md. : 1950). 179: 4383-9. PMID 17878333 DOI: 10.4049/Jimmunol.179.7.4383  0.587
2007 Mueller SN, Matloubian M, Clemens DM, Sharpe AH, Freeman GJ, Gangappa S, Larsen CP, Ahmed R. Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proceedings of the National Academy of Sciences of the United States of America. 104: 15430-5. PMID 17878315 DOI: 10.1073/Pnas.0702579104  0.486
2007 Zhang B, Maris CH, Foell J, Whitmire J, Niu L, Song J, Kwon BS, Vella AT, Ahmed R, Jacob J, Mittler RS. Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent. The Journal of Clinical Investigation. 117: 3029-41. PMID 17853940 DOI: 10.1172/Jci32426  0.599
2007 Karem KL, Reynolds M, Hughes C, Braden Z, Nigam P, Crotty S, Glidewell J, Ahmed R, Amara R, Damon IK. Monkeypox-induced immunity and failure of childhood smallpox vaccination to provide complete protection. Clinical and Vaccine Immunology : Cvi. 14: 1318-27. PMID 17715329 DOI: 10.1128/Cvi.00148-07  0.46
2007 Koehn BH, Williams MA, Borom K, Gangappa S, Pearson TC, Ahmed R, Larsen CP. Fully MHC-disparate mixed hemopoietic chimeras show specific defects in the control of chronic viral infections. Journal of Immunology (Baltimore, Md. : 1950). 179: 2616-26. PMID 17675525 DOI: 10.4049/Jimmunol.179.4.2616  0.514
2007 Mueller SN, Hosiawa-Meagher KA, Konieczny BT, Sullivan BM, Bachmann MF, Locksley RM, Ahmed R, Matloubian M. Regulation of homeostatic chemokine expression and cell trafficking during immune responses Science. 317: 670-674. PMID 17673664 DOI: 10.1126/Science.1144830  0.402
2007 Davies DH, Molina DM, Wrammert J, Miller J, Hirst S, Mu Y, Pablo J, Unal B, Nakajima-Sasaki R, Liang X, Crotty S, Karem KL, Damon IK, Ahmed R, Villarreal L, et al. Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics. 7: 1678-86. PMID 17443847 DOI: 10.1002/Pmic.200600926  0.371
2007 Velu V, Kannanganat S, Ibegbu C, Chennareddi L, Villinger F, Freeman GJ, Ahmed R, Amara RR. Elevated Expression Levels of Inhibitory Receptor Programmed Death 1 on Simian Immunodeficiency Virus-Specific CD8 T Cells during Chronic Infection but Not after Vaccination Journal of Virology. 81: 5819-5828. PMID 17376899 DOI: 10.1128/Jvi.00024-07  0.545
2007 Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nature Immunology. 8: 239-45. PMID 17304234 DOI: 10.1038/Ni1443  0.535
2007 Laughlin EM, Miller JD, James E, Fillos D, Ibegbu CC, Mittler RS, Akondy R, Kwok W, Ahmed R, Nepom G. Antigen-specific CD4+ T cells recognize epitopes of protective antigen following vaccination with an anthrax vaccine. Infection and Immunity. 75: 1852-60. PMID 17283103 DOI: 10.1128/Iai.01814-06  0.547
2007 Regoes RR, Barber DL, Ahmed R, Antia R. Estimation of the rate of killing by cytotoxic T lymphocytes in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 1599-603. PMID 17242364 DOI: 10.1073/Pnas.0508830104  0.479
2007 Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, Hanson HL, Steinberg JP, Masopust D, Wherry EJ, Altman JD, Rouse BT, Freeman GJ, Ahmed R, Grakoui A. Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. Journal of Virology. 81: 2545-53. PMID 17182670 DOI: 10.1128/Jvi.02021-06  0.62
2007 Masopust D, Murali-Krishna K, Ahmed R. Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: It is even bigger than we thought Journal of Virology. 81: 2002-2011. PMID 17151096 DOI: 10.1128/Jvi.01459-06  0.621
2007 Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, Subramaniam S, Blattman JN, Barber DL, Ahmed R. Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection (DOI:10.1016/j.immuni.2007.09.006) Immunity. 27: 824. DOI: 10.1016/J.Immuni.2007.11.006  0.849
2006 Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. The Journal of Experimental Medicine. 203: 2223-7. PMID 17000870 DOI: 10.1084/Jem.20061800  0.551
2006 Vezys V, Masopust D, Kemball CC, Barber DL, O'Mara LA, Larsen CP, Pearson TC, Ahmed R, Lukacher AE. Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection. The Journal of Experimental Medicine. 203: 2263-9. PMID 16966427 DOI: 10.1084/Jem.20060995  0.626
2006 Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, ... ... Ahmed R, et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature. 443: 350-4. PMID 16921384 DOI: 10.1038/Nature05115  0.683
2006 Grakoui A, John Wherry E, Hanson HL, Walker C, Ahmed R. Turning on the off switch: regulation of anti-viral T cell responses in the liver by the PD-1/PD-L1 pathway. Journal of Hepatology. 45: 468-72. PMID 16901572 DOI: 10.1016/J.Jhep.2006.07.009  0.502
2006 Wherry EJ, Day CL, Draenert R, Miller JD, Kiepiela P, Woodberry T, Brander C, Addo M, Klenerman P, Ahmed R, Walker BD. HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory. Virology. 353: 366-73. PMID 16860834 DOI: 10.1016/J.Virol.2006.06.017  0.694
2006 Masopust D, Ha SJ, Vezys V, Ahmed R. Stimulation history dictates memory CD8 T cell phenotype: Implications for prime-boost vaccination Journal of Immunology. 177: 831-839. PMID 16818737 DOI: 10.4049/Jimmunol.177.2.831  0.578
2006 Ganusov VV, Pilyugin SS, Ahmed R, Antia R. How does cross-reactive stimulation affect the longevity of CD8+ T cell memory? Plos Computational Biology. 2: e55. PMID 16789812 DOI: 10.1371/Journal.Pcbi.0020055  0.427
2006 Crotty S, McCausland MM, Aubert RD, Wherry EJ, Ahmed R. Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease. Blood. 108: 3085-93. PMID 16788096 DOI: 10.1182/Blood-2006-04-018929  0.858
2006 Kalia V, Sarkar S, Gourley TS, Rouse BT, Ahmed R. Differentiation of memory B and T cells. Current Opinion in Immunology. 18: 255-64. PMID 16632337 DOI: 10.1016/J.Coi.2006.03.020  0.455
2006 Kersh EN, Fitzpatrick DR, Murali-Krishna K, Shires J, Speck SH, Boss JM, Ahmed R. Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 4083-93. PMID 16547244 DOI: 10.4049/Jimmunol.176.7.4083  0.506
2006 Pulendran B, Ahmed R. Translating innate immunity into immunological memory: implications for vaccine development. Cell. 124: 849-63. PMID 16497593 DOI: 10.1016/J.Cell.2006.02.019  0.404
2006 Koehn B, Gangappa S, Miller JD, Ahmed R, Larsen CP. Patients, pathogens, and protective immunity: the relevance of virus-induced alloreactivity in transplantation. Journal of Immunology (Baltimore, Md. : 1950). 176: 2691-6. PMID 16493023 DOI: 10.4049/Jimmunol.176.5.2691  0.413
2006 Querec T, Bennouna S, Alkan S, Laouar Y, Gorden K, Flavell R, Akira S, Ahmed R, Pulendran B. Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity. The Journal of Experimental Medicine. 203: 413-24. PMID 16461338 DOI: 10.1084/Jem.20051720  0.402
2006 Masopust D, Vezys V, Wherry EJ, Barber DL, Ahmed R. Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population. Journal of Immunology (Baltimore, Md. : 1950). 176: 2079-83. PMID 16455963 DOI: 10.4049/Jimmunol.176.4.2079  0.688
2006 Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, Freeman GJ, Ahmed R. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature. 439: 682-7. PMID 16382236 DOI: 10.1038/Nature04444  0.734
2006 Ganusov VV, Pilyugin SS, Ahmed R, Antia R. Correction: How Does Cross-Reactive Stimulation Affect the Longevity of CD8+ T Cell Memory? Plos Computational Biology. 2: e97. DOI: 10.1371/Journal.Pcbi.0020097  0.42
2006 Haining WN, Ebert B, Subramanian A, Wherry EJ, Evans J, Mak R, Rivoli S, Angelosanto J, Pretz J, Kaech S, Ahmed R, Nadler LM, Golub TR. All Memory Lymphocytes Share a Common Differentiation Program. Blood. 108: 865-865. DOI: 10.1182/Blood.V108.11.865.865  0.753
2006 Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, ... ... Ahmed R, et al. Erratum: Corrigendum: Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin Nature Immunology. 7: 113-113. DOI: 10.1038/Ni0106-113  0.729
2006 Ganusov VV, Pilyugin SS, de Boer RJ, Murali-Krishna K, Ahmed R, Antia R. Erratum to “Quantifying cell turnover using CFSE data” [J. Immunol. Methods (298) (2005) 183] Journal of Immunological Methods. 317: 186-187. DOI: 10.1016/J.Jim.2006.09.008  0.305
2006 Haining WN, Ebert B, Subramanian A, Kaech S, Ahmed R, Nadler L, Wherry EJ, Golub T. Su.66. Memory T-Cells in Mice and Humans Share a Common Molecular Program of Differentiation Regardless of Phenotype, Lineage Or Species Clinical Immunology. 119: S182-S183. DOI: 10.1016/J.Clim.2006.04.493  0.712
2005 Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, ... ... Ahmed R, et al. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nature Immunology. 6: 1236-44. PMID 16273099 DOI: 10.1038/Ni1268  0.797
2005 Li ZN, Mueller SN, Ye L, Bu Z, Yang C, Ahmed R, Steinhauer DA. Chimeric influenza virus hemagglutinin proteins containing large domains of the Bacillus anthracis protective antigen: protein characterization, incorporation into infectious influenza viruses, and antigenicity. Journal of Virology. 79: 10003-12. PMID 16014960 DOI: 10.1128/Jvi.79.15.10003-10012.2005  0.651
2005 Wherry EJ, Blattman JN, Ahmed R. Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination. Journal of Virology. 79: 8960-8. PMID 15994790 DOI: 10.1128/Jvi.79.14.8960-8968.2005  0.811
2005 Miller JD, Masopust D, Wherry EJ, Kaech S, Silvestri G, Ahmed R. Differentiation of CD8 T cells in response to acute and chronic viral infections: Implications for HIV vaccine development Current Drug Targets - Infectious Disorders. 5: 121-129. PMID 15975018 DOI: 10.2174/1568005054201544  0.775
2005 Ganusov VV, Pilyugin SS, de Boer RJ, Murali-Krishna K, Ahmed R, Antia R. Quantifying cell turnover using CFSE data. Journal of Immunological Methods. 298: 183-200. PMID 15847808 DOI: 10.1016/J.Jim.2005.01.011  0.334
2005 Manders PM, Hunter PJ, Telaranta AI, Carr JM, Marshall JL, Carrasco M, Murakami Y, Palmowski MJ, Cerundolo V, Kaech SM, Ahmed R, Fearon DT. BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 102: 7418-25. PMID 15833813 DOI: 10.1073/Pnas.0501585102  0.759
2005 Gupta M, Greer P, Mahanty S, Shieh WJ, Zaki SR, Ahmed R, Rollin PE. CD8-mediated protection against Ebola virus infection is perforin dependent. Journal of Immunology (Baltimore, Md. : 1950). 174: 4198-202. PMID 15778381 DOI: 10.4049/Jimmunol.174.7.4198  0.492
2005 Kitchen SG, Whitmire JK, Jones NR, Galic Z, Kitchen CM, Ahmed R, Zack JA. The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens. Proceedings of the National Academy of Sciences of the United States of America. 102: 3794-9. PMID 15731353 DOI: 10.1073/Pnas.0406603102  0.566
2005 Antia R, Ganusov VV, Ahmed R. The role of models in understanding CD8+ T-cell memory. Nature Reviews. Immunology. 5: 101-11. PMID 15662368 DOI: 10.1038/Nri1550  0.512
2005 Becker TC, Coley SM, Wherry EJ, Ahmed R. Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 1269-73. PMID 15661882 DOI: 10.4049/Jimmunol.174.3.1269  0.802
2005 Kapasi ZF, McRae ML, Ahmed R. Suppression of viral specific primary T-cell response following intense physical exercise in young but not old mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 98: 663-71. PMID 15448122 DOI: 10.1152/Japplphysiol.00510.2004  0.522
2005 Rouzine IM, Murali-Krishna K, Ahmed R. Generals die in friendly fire, or modeling immune response to HIV Journal of Computational and Applied Mathematics. 184: 258-274. DOI: 10.1016/J.Cam.2004.08.018  0.539
2004 Mandal M, Kawamura KS, Wherry EJ, Ahmed R, Lee KD. Cytosolic delivery of viral nucleoprotein by listeriolysin O-liposome induces enhanced specific cytotoxic T lymphocyte response and protective immunity. Molecular Pharmaceutics. 1: 2-8. PMID 15832496 DOI: 10.1021/Mp034021M  0.579
2004 Gourley TS, Wherry EJ, Masopust D, Ahmed R. Generation and maintenance of immunological memory. Seminars in Immunology. 16: 323-33. PMID 15528077 DOI: 10.1016/J.Smim.2004.08.013  0.649
2004 Wherry EJ, Barber DL, Kaech SM, Blattman JN, Ahmed R. Antigen-independent memory CD8 T cells do not develop during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. 101: 16004-9. PMID 15505208 DOI: 10.1073/Pnas.0407192101  0.869
2004 Sabbagh L, Kaech SM, Bourbonnière M, Woo M, Cohen LY, Haddad EK, Labrecque N, Ahmed R, Sékaly RP. The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 173: 5425-33. PMID 15494489 DOI: 10.4049/Jimmunol.173.9.5425  0.672
2004 Latner DR, Kaech SM, Ahmed R. Enhanced expression of cell cycle regulatory genes in virus-specific memory CD8+ T cells. Journal of Virology. 78: 10953-9. PMID 15452215 DOI: 10.1128/Jvi.78.20.10953-10959.2004  0.721
2004 Quinn CP, Dull PM, Semenova V, Li H, Crotty S, Taylor TH, Steward-Clark E, Stamey KL, Schmidt DS, Stinson KW, Freeman AE, Elie CM, Martin SK, Greene C, Aubert RD, ... ... Ahmed R, et al. Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. The Journal of Infectious Diseases. 190: 1228-36. PMID 15346332 DOI: 10.1086/423937  0.757
2004 Masopust D, Ahmed R. Reflections on CD8 T-cell activation and memory Immunologic Research. 29: 151-160. PMID 15181278 DOI: 10.1385/Ir:29:1-3:151  0.604
2004 Wherry EJ, Ahmed R. Memory CD8 T-cell differentiation during viral infection. Journal of Virology. 78: 5535-45. PMID 15140950 DOI: 10.1128/Jvi.78.11.5535-5545.2004  0.736
2004 Crotty S, Ahmed R. Immunological memory in humans. Seminars in Immunology. 16: 197-203. PMID 15130504 DOI: 10.1016/J.Smim.2004.02.008  0.432
2004 Wu Z, Roberts M, Porter M, Walker F, Wherry EJ, Kelly J, Gadina M, Silva EM, DosReis GA, Lopes MF, O'Shea J, Leonard WJ, Ahmed R, Siegel RM. Viral FLIP impairs survival of activated T cells and generation of CD8+ T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 172: 6313-23. PMID 15128821 DOI: 10.4049/Jimmunol.172.10.6313  0.74
2004 Crotty S, Aubert RD, Glidewell J, Ahmed R. Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system. Journal of Immunological Methods. 286: 111-22. PMID 15087226 DOI: 10.1016/J.Jim.2003.12.015  0.809
2004 Derjuga A, Gourley TS, Holm TM, Heng HH, Shivdasani RA, Ahmed R, Andrews NC, Blank V. Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Molecular and Cellular Biology. 24: 3286-94. PMID 15060151 DOI: 10.1128/Mcb.24.8.3286-3294.2004  0.367
2004 Masopust D, Kaech SM, Wherry EJ, Ahmed R. The role of programming in memory T-cell development. Current Opinion in Immunology. 16: 217-25. PMID 15023416 DOI: 10.1016/J.Coi.2004.02.005  0.76
2004 Gupta M, Mahanty S, Greer P, Towner JS, Shieh WJ, Zaki SR, Ahmed R, Rollin PE. Persistent infection with ebola virus under conditions of partial immunity. Journal of Virology. 78: 958-67. PMID 14694127 DOI: 10.1128/Jvi.78.2.958-967.2004  0.627
2003 Ford ML, Onami TM, Sperling AI, Ahmed R, Evavold BD. CD43 modulates severity and onset of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 171: 6527-33. PMID 14662853 DOI: 10.4049/Jimmunol.171.12.6527  0.526
2003 Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nature Immunology. 4: 1191-8. PMID 14625547 DOI: 10.1038/Ni1009  0.76
2003 Crotty S, Felgner P, Davies H, Glidewell J, Villarreal L, Ahmed R. Cutting edge: long-term B cell memory in humans after smallpox vaccination. Journal of Immunology (Baltimore, Md. : 1950). 171: 4969-73. PMID 14607890 DOI: 10.4049/Jimmunol.171.10.4969  0.482
2003 van der Most RG, Murali-Krishna K, Lanier JG, Wherry EJ, Puglielli MT, Blattman JN, Sette A, Ahmed R. Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation. Virology. 315: 93-102. PMID 14592762 DOI: 10.1016/J.Virol.2003.07.001  0.84
2003 Pilyugin SS, Ganusov VV, Murali-Krishna K, Ahmed R, Antia R. The rescaling method for quantifying the turnover of cell populations. Journal of Theoretical Biology. 225: 275-83. PMID 14575660 DOI: 10.1016/S0022-5193(03)00245-5  0.301
2003 Seder RA, Ahmed R. Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nature Immunology. 4: 835-842. PMID 12942084 DOI: 10.1038/Ni969  0.599
2003 Wan J, Martinvalet D, Ji X, Lois C, Kaech SM, Von Andrian UH, Lieberman J, Ahmed R, Manjunath N. The Bcl-2 family pro-apoptotic molecule, BNIP3 regulates activation-induced cell death of effector cytotoxic T lymphocytes. Immunology. 110: 10-7. PMID 12941136 DOI: 10.1046/J.1365-2567.2003.01710.X  0.635
2003 Mahanty S, Gupta M, Paragas J, Bray M, Ahmed R, Rollin PE. Protection from lethal infection is determined by innate immune responses in a mouse model of Ebola virus infection. Virology. 312: 415-24. PMID 12919746 DOI: 10.1016/S0042-6822(03)00233-2  0.391
2003 Barber DL, Wherry EJ, Ahmed R. Cutting edge: rapid in vivo killing by memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 27-31. PMID 12816979 DOI: 10.4049/Jimmunol.171.1.27  0.734
2003 Adams AB, Williams MA, Jones TR, Shirasugi N, Durham MM, Kaech SM, Wherry EJ, Onami T, Lanier JG, Kokko KE, Pearson TC, Ahmed R, Larsen CP. Heterologous immunity provides a potent barrier to transplantation tolerance. The Journal of Clinical Investigation. 111: 1887-95. PMID 12813024 DOI: 10.1172/Jci17477  0.838
2003 Kersh EN, Kaech SM, Onami TM, Moran M, Wherry EJ, Miceli MC, Ahmed R. TCR signal transduction in antigen-specific memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 5455-63. PMID 12759421 DOI: 10.4049/Jimmunol.170.11.5455  0.779
2003 Antia R, Bergstrom CT, Pilyugin SS, Kaech SM, Ahmed R. Models of CD8+ responses: 1. What is the antigen-independent proliferation program. Journal of Theoretical Biology. 221: 585-98. PMID 12713942 DOI: 10.1006/Jtbi.2003.3208  0.711
2003 Grayson JM, Laniewski NG, Lanier JG, Ahmed R. Mitochondrial potential and reactive oxygen intermediates in antigen-specific CD8+ T cells during viral infection. Journal of Immunology (Baltimore, Md. : 1950). 170: 4745-51. PMID 12707355 DOI: 10.4049/Jimmunol.170.9.4745  0.857
2003 Blattman JN, Grayson JM, Wherry EJ, Kaech SM, Smith KA, Ahmed R. Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nature Medicine. 9: 540-7. PMID 12692546 DOI: 10.1038/Nm866  0.823
2003 Kaech SM, Ahmed R. Immunology. CD8 T cells remember with a little help. Science (New York, N.Y.). 300: 263-5. PMID 12690179 DOI: 10.1126/Science.1084511  0.759
2003 Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R. Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. Journal of Virology. 77: 4911-27. PMID 12663797 DOI: 10.1128/Jvi.77.8.4911-4927.2003  0.837
2003 Williams MA, Adams AB, Walsh MB, Shirasugi N, Onami TM, Pearson TC, Ahmed R, Larsen CP. Primary and secondary immunocompetence in mixed allogeneic chimeras. Journal of Immunology (Baltimore, Md. : 1950). 170: 2382-9. PMID 12594261 DOI: 10.4049/Jimmunol.170.5.2382  0.577
2003 Shedlock DJ, Whitmire JK, Tan J, MacDonald AS, Ahmed R, Shen H. Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. Journal of Immunology (Baltimore, Md. : 1950). 170: 2053-63. PMID 12574376 DOI: 10.4049/Jimmunol.170.4.2053  0.573
2003 Wherry EJ, Teichgräber V, Becker TC, Masopust D, Kaech SM, Antia R, von Andrian UH, Ahmed R. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nature Immunology. 4: 225-34. PMID 12563257 DOI: 10.1038/Ni889  0.834
2003 Shen H, Whitmire JK, Fan X, Shedlock DJ, Kaech SM, Ahmed R. A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes. Journal of Immunology (Baltimore, Md. : 1950). 170: 1443-51. PMID 12538706 DOI: 10.4049/Jimmunol.170.3.1443  0.757
2003 Slifka MK, Blattman JN, Sourdive DJ, Liu F, Huffman DL, Wolfe T, Hughes A, Oldstone MB, Ahmed R, Von Herrath MG. Preferential escape of subdominant CD8+ T cells during negative selection results in an altered antiviral T cell hierarchy. Journal of Immunology (Baltimore, Md. : 1950). 170: 1231-9. PMID 12538681 DOI: 10.4049/Jimmunol.170.3.1231  0.827
2003 Crotty S, Kersh EN, Cannons J, Schwartzberg PL, Ahmed R. SAP is required for generating long-term humoral immunity. Nature. 421: 282-7. PMID 12529646 DOI: 10.1038/Nature01318  0.581
2003 Most RGvd, Murali‐Krishna K, Ahmed R. Prolonged presence of effector-memory CD8 T cells in the central nervous system after dengue virus encephalitis International Immunology. 15: 119-125. PMID 12502732 DOI: 10.1093/Intimm/Dxg009  0.621
2003 Hathcock KS, Kaech SM, Ahmed R, Hodes RJ. Induction of telomerase activity and maintenance of telomere length in virus-specific effector and memory CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 147-52. PMID 12496394 DOI: 10.4049/Jimmunol.170.1.147  0.768
2003 Villinger F, Mayne AE, Bostik P, Mori K, Jensen PE, Ahmed R, Ansari AA. Evidence for Antibody-Mediated Enhancement of Simian Immunodeficiency Virus (SIV) Gag Antigen Processing and Cross Presentation in SIV-Infected Rhesus Macaques Journal of Virology. 77: 10-24. PMID 12477806 DOI: 10.1128/Jvi.77.1.10-24.2003  0.443
2002 Kaech SM, Hemby S, Kersh E, Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation Cell. 111: 837-851. PMID 12526810 DOI: 10.1016/S0092-8674(02)01139-X  0.758
2002 Williams MA, Onami TM, Adams AB, Durham MM, Pearson TC, Ahmed R, Larsen CP. Cutting edge: persistent viral infection prevents tolerance induction and escapes immune control following CD28/CD40 blockade-based regimen. Journal of Immunology (Baltimore, Md. : 1950). 169: 5387-91. PMID 12421910 DOI: 10.4049/Jimmunol.169.10.5387  0.564
2002 Wherry EJ, Becker TC, Boone D, Kaja MK, Ma A, Ahmed R. Homeostatic proliferation but not the generation of virus specific memory CD8 T cells is impaired in the absence of IL-15 or IL-15Ralpha. Advances in Experimental Medicine and Biology. 512: 165-75. PMID 12405201 DOI: 10.1007/978-1-4615-0757-4_22  0.799
2002 Grayson JM, Harrington LE, Lanier JG, Wherry EJ, Ahmed R. Differential sensitivity of naive and memory CD8+ T cells to apoptosis in vivo. Journal of Immunology (Baltimore, Md. : 1950). 169: 3760-70. PMID 12244170 DOI: 10.4049/Jimmunol.169.7.3760  0.86
2002 McMahon CW, Zajac AJ, Jamieson AM, Corral L, Hammer GE, Ahmed R, Raulet DH. Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 1444-52. PMID 12133970 DOI: 10.4049/Jimmunol.169.3.1444  0.583
2002 Kapasi ZF, Murali-Krishna K, McRae ML, Ahmed R. Defective generation but normal maintenance of memory T cells in old mice. European Journal of Immunology. 32: 1567-73. PMID 12115639 DOI: 10.1002/1521-4141(200206)32:6<1567::Aid-Immu1567>3.0.Co;2-P  0.526
2002 Becker TC, Wherry EJ, Boone D, Murali-Krishna K, Antia R, Ma A, Ahmed R. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. The Journal of Experimental Medicine. 195: 1541-8. PMID 12070282 DOI: 10.1084/Jem.20020369  0.824
2002 Onami TM, Harrington LE, Williams MA, Galvan M, Larsen CP, Pearson TC, Manjunath N, Baum LG, Pearce BD, Ahmed R. Dynamic regulation of T cell immunity by CD43. Journal of Immunology (Baltimore, Md. : 1950). 168: 6022-31. PMID 12055210 DOI: 10.4049/Jimmunol.168.12.6022  0.774
2002 van der Most RG, Harrington LE, Giuggio V, Mahar PL, Ahmed R. Yellow fever virus 17D envelope and NS3 proteins are major targets of the antiviral T cell response in mice. Virology. 296: 117-24. PMID 12036323 DOI: 10.1006/Viro.2002.1432  0.766
2002 Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nature Reviews. Immunology. 2: 251-62. PMID 12001996 DOI: 10.1038/Nri778  0.785
2002 Suresh M, Lanier G, Large MK, Whitmire JK, Altman JD, Ruddle NH, Ahmed R. Role of lymphotoxin alpha in T-cell responses during an acute viral infection. Journal of Virology. 76: 3943-51. PMID 11907234 DOI: 10.1128/Jvi.76.8.3943-3951.2002  0.57
2002 Harrington LE, Most Rv Rv, Whitton JL, Ahmed R. Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope. Journal of Virology. 76: 3329-37. PMID 11884558 DOI: 10.1128/Jvi.76.7.3329-3337.2002  0.84
2002 Blattman JN, Antia R, Sourdive DJ, Wang X, Kaech SM, Murali-Krishna K, Altman JD, Ahmed R. Estimating the precursor frequency of naive antigen-specific CD8 T cells. The Journal of Experimental Medicine. 195: 657-64. PMID 11877489 DOI: 10.1084/Jem.20001021  0.834
2001 Grayson JM, Lanier JG, Harrington LE, Altman JD, Ahmed R. Analysis of Mitochondrial Function in Antigen Specific na ve, Effector and MEmory CD8 + T Cells. Thescientificworldjournal. 1: 53. PMID 30147516 DOI: 10.1100/Tsw.2001.188  0.864
2001 Suresh M, Whitmire JK, Harrington LE, Larsen CP, Pearson TC, Altman JD, Ahmed R. Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 167: 5565-73. PMID 11698427 DOI: 10.4049/Jimmunol.167.10.5565  0.774
2001 Williams MA, Tan JT, Adams AB, Durham MM, Shirasugi N, Whitmire JK, Harrington LE, Ahmed R, Pearson TC, Larsen CP. Characterization of virus-mediated inhibition of mixed chimerism and allospecific tolerance. Journal of Immunology (Baltimore, Md. : 1950). 167: 4987-95. PMID 11673506 DOI: 10.4049/Jimmunol.167.9.4987  0.774
2001 Boer RJD, Oprea M, Antia R, Murali-Krishna K, Ahmed R, Perelson AS. Recruitment Times, Proliferation, and Apoptosis Rates during the CD8+ T-Cell Response to Lymphocytic Choriomeningitis Virus Journal of Virology. 75: 10663-10669. PMID 11602708 DOI: 10.1128/Jvi.75.22.10663-10669.2001  0.578
2001 Wu-Hsieh BA, Whitmire JK, de Fries R, Lin JS, Matloubian M, Ahmed R. Distinct CD8 T cell functions mediate susceptibility to histoplasmosis during chronic viral infection. Journal of Immunology (Baltimore, Md. : 1950). 167: 4566-73. PMID 11591785 DOI: 10.4049/Jimmunol.167.8.4566  0.598
2001 Whitmire JK, Ahmed R. The economy of T-cell memory: CD4+ recession in times of CD8+ stability? Nature Medicine. 7: 892-3. PMID 11479617 DOI: 10.1038/90923  0.588
2001 Grayson JM, Lanier JG, Altman JD, Ahmed R. The role of p53 in regulating antiviral T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 167: 1333-7. PMID 11466350 DOI: 10.4049/Jimmunol.167.3.1333  0.869
2001 Czar MJ, Kersh EN, Mijares LA, Lanier G, Lewis J, Yap G, Chen A, Sher A, Duckett CS, Ahmed R, Schwartzberg PL. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP Proceedings of the National Academy of Sciences of the United States of America. 98: 7449-7454. PMID 11404475 DOI: 10.1073/Pnas.131193098  0.419
2001 Gupta M, Mahanty S, Ahmed R, Rollin PE. Monocyte-Derived Human Macrophages and Peripheral Blood Mononuclear Cells Infected with Ebola Virus Secrete MIP-1α and TNF-α and Inhibit Poly-IC-Induced IFN-α in Vitro Virology. 284: 20-25. PMID 11352664 DOI: 10.1006/Viro.2001.0836  0.333
2001 Puglielli MT, Zajac AJ, van der Most RG, Dzuris JL, Sette A, Altman JD, Ahmed R. In vivo selection of a lymphocytic choriomeningitis virus variant that affects recognition of the GP33-43 epitope by H-2Db but not H-2Kb. Journal of Virology. 75: 5099-107. PMID 11333891 DOI: 10.1128/Jvi.75.11.5099-5107.2001  0.483
2001 Kaech SM, Ahmed R. Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells. Nature Immunology. 2: 415-22. PMID 11323695 DOI: 10.1038/87720  0.74
2001 Gupta M, Mahanty S, Bray M, Ahmed R, Rollin PE. Passive Transfer of Antibodies Protects Immunocompetent and Immunodeficient Mice against Lethal Ebola Virus Infection without Complete Inhibition of Viral Replication Journal of Virology. 75: 4649-4654. PMID 11312335 DOI: 10.1128/Jvi.75.10.4649-4654.2001  0.402
2001 King C, Mueller Hoenger R, Malo Cleary M, Murali-Krishna K, Ahmed R, King E, Sarvetnick N. Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses. Nature Medicine. 7: 206-14. PMID 11175852 DOI: 10.1038/84659  0.49
2001 Grayson JM, Murali-Krishna K, Altman JD, Ahmed R. Gene expression in antigen-specific CD8+ T cells during viral infection. Journal of Immunology (Baltimore, Md. : 1950). 166: 795-9. PMID 11145652 DOI: 10.4049/Jimmunol.166.2.795  0.599
2000 Blattman JN, Sourdive DJ, Murali-Krishna K, Ahmed R, Altman JD. Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 6081-90. PMID 11086040 DOI: 10.4049/Jimmunol.165.11.6081  0.817
2000 van Der Most RG, Murali-Krishna K, Ahmed R, Strauss JH. Chimeric yellow fever/dengue virus as a candidate dengue vaccine: quantitation of the dengue virus-specific CD8 T-cell response. Journal of Virology. 74: 8094-101. PMID 10933719 DOI: 10.1128/Jvi.74.17.8094-8101.2000  0.576
2000 Murali-Krishna K, Ahmed R. Cutting Edge: Naive T Cells Masquerading as Memory Cells Journal of Immunology. 165: 1733-1737. PMID 10925249 DOI: 10.4049/Jimmunol.165.4.1733  0.599
2000 Whitmire JK, Ahmed R. Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses. Current Opinion in Immunology. 12: 448-55. PMID 10899032 DOI: 10.1016/S0952-7915(00)00119-9  0.605
2000 Whitmire JK, Murali-Krishna K, Altman J, Ahmed R. Antiviral CD4 and CD8 T-cell memory: differences in the size of the response and activation requirements. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 373-9. PMID 10794058 DOI: 10.1098/Rstb.2000.0577  0.583
2000 Grayson JM, Zajac AJ, Altman JD, Ahmed R. Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 164: 3950-4. PMID 10754284 DOI: 10.4049/Jimmunol.164.8.3950  0.612
2000 Harrington LE, Galvan M, Baum LG, Altman JD, Ahmed R. Differentiating between memory and effector CD8 T cells by altered expression of cell surface O-glycans. The Journal of Experimental Medicine. 191: 1241-6. PMID 10748241 DOI: 10.1084/Jem.191.7.1241  0.799
2000 Tan JT, Whitmire JK, Murali-Krishna K, Ahmed R, Altman JD, Mittler RS, Sette A, Pearson TC, Larsen CP. 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination. Journal of Immunology (Baltimore, Md. : 1950). 164: 2320-5. PMID 10679066 DOI: 10.4049/Jimmunol.164.5.2320  0.528
1999 Puglielli MT, Browning JL, Brewer AW, Schreiber RD, Shieh WJ, Altman JD, Oldstone MB, Zaki SR, Ahmed R. Reversal of virus-induced systemic shock and respiratory failure by blockade of the lymphotoxin pathway. Nature Medicine. 5: 1370-4. PMID 10581078 DOI: 10.1038/70938  0.477
1999 Murali-Krishna K, Lau LL, Sambhara S, Lemonnier F, Altman J, Ahmed R. Persistence of memory CD8 T cells in MHC class I-deficient mice. Science (New York, N.Y.). 286: 1377-81. PMID 10558996 DOI: 10.1126/Science.286.5443.1377  0.599
1999 Lanier JG, Newman MJ, Lee EM, Sette A, Ahmed R. Peptide vaccination using nonionic block copolymers induces protective anti-viral CTL responses. Vaccine. 18: 549-57. PMID 10519946  0.832
1999 Doling AM, Ballard JD, Shen H, Krishna KM, Ahmed R, Collier RJ, Starnbach MN. Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity. Infection and Immunity. 67: 3290-6. PMID 10377103 DOI: 10.1128/Iai.67.7.3290-3296.1999  0.419
1999 McHeyzer-Williams MG, Ahmed R. B cell memory and the long-lived plasma cell. Current Opinion in Immunology. 11: 172-179. PMID 10322151 DOI: 10.1016/S0952-7915(99)80029-6  0.407
1999 Cousens LP, Peterson R, Hsu S, Dorner A, Altman JD, Ahmed R, Biron CA. Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection. The Journal of Experimental Medicine. 189: 1315-28. PMID 10209048 DOI: 10.1084/Jem.189.8.1315  0.47
1999 Matloubian M, Suresh M, Glass A, Galvan M, Chow K, Whitmire JK, Walsh CM, Clark WR, Ahmed R. A role for perforin in downregulating T-cell responses during chronic viral infection Journal of Virology. 73: 2527-2536. PMID 9971838 DOI: 10.1128/Jvi.73.3.2527-2536.1999  0.613
1999 Antia R, Pilyugin SS, Ahmed R. Models of immune memory: on the role of cross-reactive stimulation, competition, and homeostasis in maintaining immune memory. Proceedings of the National Academy of Sciences of the United States of America. 95: 14926-31. PMID 9843992 DOI: 10.1073/Pnas.95.25.14926  0.447
1998 Murali-Krishna K, Altman JD, Suresh M, Sourdive D, Zajac A, Ahmed R. In vivo dynamics of anti-viral CD8 T cell responses to different epitopes. An evaluation of bystander activation in primary and secondary responses to viral infection. Advances in Experimental Medicine and Biology. 452: 123-42. PMID 9889966 DOI: 10.1007/978-1-4615-5355-7_14  0.641
1998 Zajac AJ, Blattman JN, Murali-Krishna K, Sourdive DJ, Suresh M, Altman JD, Ahmed R. Viral immune evasion due to persistence of activated T cells without effector function. The Journal of Experimental Medicine. 188: 2205-13. PMID 9858507 DOI: 10.1084/Jem.188.12.2205  0.811
1998 Whitmire JK, Asano MS, Murali-Krishna K, Suresh M, Ahmed R. Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infection. Journal of Virology. 72: 8281-8. PMID 9733872 DOI: 10.1128/Jvi.72.10.8281-8288.1998  0.592
1998 Zajac AJ, Murali-Krishna K, Blattman JN, Ahmed R. Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells. Current Opinion in Immunology. 10: 444-9. PMID 9722921 DOI: 10.1016/S0952-7915(98)80119-2  0.806
1998 Flynn KJ, Belz GT, Altman JD, Ahmed R, Woodland DL, Doherty PC. Virus-specific CD8+ T cells in primary and secondary influenza pneumonia. Immunity. 8: 683-91. PMID 9655482 DOI: 10.1016/S1074-7613(00)80573-7  0.533
1998 Sourdive DJD, Murali-Krishna K, Altman JD, Zajac AJ, Whitmire JK, Pannetier C, Kourilsky P, Evavold B, Sette A, Ahmed R. Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection Journal of Experimental Medicine. 188: 71-82. PMID 9653085 DOI: 10.1084/Jem.188.1.71  0.647
1998 Slifka MK, Ahmed R. Long-lived plasma cells: a mechanism for maintaining persistent antibody production Current Opinion in Immunology. 10: 252-258. PMID 9638360 DOI: 10.1016/S0952-7915(98)80162-3  0.373
1998 Slifka MK, Antia R, Whitmire JK, Ahmed R. Humoral immunity due to long-lived plasma cells. Immunity. 8: 363-72. PMID 9529153 DOI: 10.1016/S1074-7613(00)80541-5  0.422
1998 Murali-Krishna K, Altman JD, Suresh M, Sourdive DJ, Zajac AJ, Miller JD, Slansky J, Ahmed R. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity. 8: 177-87. PMID 9491999 DOI: 10.1016/S1074-7613(00)80470-7  0.643
1998 Shen H, Miller JF, Fan X, Kolwyck D, Ahmed R, Harty JT. Compartmentalization of bacterial antigens: Differential effects on priming of CD8 T cells and protective immunity Cell. 92: 535-545. PMID 9491894 DOI: 10.1016/S0092-8674(00)80946-0  0.588
1998 Most RGvd, Murali-Krishna K, Whitton JL, Oseroff C, Alexander J, Southwood S, Sidney J, Chesnut RW, Sette A, Ahmed R. Identification of Db- and Kb-Restricted Subdominant Cytotoxic T-Cell Responses in Lymphocytic Choriomeningitis Virus-Infected Mice Virology. 240: 158-167. PMID 9448700 DOI: 10.1006/Viro.1997.8934  0.594
1997 Jensen ER, Selvakumar R, Shen H, Ahmed R, Wettstein FO, Miller JF. Recombinant Listeria monocytogenes vaccination eliminates papillomavirus-induced tumors and prevents papilloma formation from viral DNA. Journal of Virology. 71: 8467-8474. PMID 9343203 DOI: 10.1128/Jvi.71.11.8467-8474.1997  0.39
1997 Jensen ER, Shen H, Wettstein FO, Ahmed R, Miller JF. Recombinant Listeria monocytogenes as a live vaccine vehicle and a probe for studying cell‐mediated immunity Immunological Reviews. 158: 147-157. PMID 9314083 DOI: 10.1111/J.1600-065X.1997.Tb01001.X  0.538
1997 McChesney MB, Miller CJ, Rota PA, Zhu YD, Antipa L, Lerche NW, Ahmed R, Bellini WJ. Experimental measles: I. Pathogenesis in the normal and the immunized host Virology. 233: 74-84. PMID 9201218 DOI: 10.1006/Viro.1997.8576  0.437
1997 Slifka MK, Whitmire JK, Ahmed R. Bone Marrow Contains Virus-Specific Cytotoxic T Lymphocytes Blood. 90: 2103-2108. DOI: 10.1182/Blood.V90.5.2103  0.501
1996 Slifka MK, Ahmed R. Long-term antibody production is sustained by antibody-secreting cells in the bone marrow following acute viral infection Annals of the New York Academy of Sciences. 797: 166-176. PMID 8993360 DOI: 10.1111/J.1749-6632.1996.Tb52958.X  0.362
1996 Whitmire JK, Slifka MK, Grewal IS, Flavell RA, Ahmed R. CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection. Journal of Virology. 70: 8375-81. PMID 8970958 DOI: 10.1128/Jvi.70.12.8375-8381.1996  0.564
1996 Slifka MK, Ahmed R. Limiting dilution analysis of virus-specific memory B cells by an ELISPOT assay Journal of Immunological Methods. 199: 37-46. PMID 8960096 DOI: 10.1016/S0022-1759(96)00146-9  0.483
1996 Slifka MK, Ahmed R. Long-term humoral immunity against viruses: revisiting the issue of plasma cell longevity Trends in Microbiology. 4: 394-400. PMID 8899965 DOI: 10.1016/0966-842X(96)10059-7  0.37
1996 Ahmed R. Tickling memory T cells Science. 272: 1904. PMID 8658161 DOI: 10.1126/Science.272.5270.1904  0.516
1996 Slifka MK, Shen H, Matloubian M, Jensen ER, Miller JF, Ahmed R. Antiviral cytotoxic T-cell memory by vaccination with recombinant Listeria monocytogenes. Journal of Virology. 70: 2902-10. PMID 8627765 DOI: 10.1128/Jvi.70.5.2902-2910.1996  0.55
1996 Sydora BC, Jamieson BD, Ahmed R, Kronenberg M. Intestinal intraepithelial lymphocytes respond to systemic lymphocytic choriomeningitis virus infection. Cellular Immunology. 167: 161-169. PMID 8603424 DOI: 10.1006/Cimm.1996.0023  0.567
1996 Ahmed R, Gray D. Immunological memory and protective immunity: Understanding their relation Science. 272: 54-60. PMID 8600537 DOI: 10.1126/Science.272.5258.54  0.434
1996 Wright KE, Ahmed R, Buchmeier MJ. Persistent infection of mice with Pichinde virus associated with failure to thrive. Microbial Pathogenesis. 19: 73-82. PMID 8577237 DOI: 10.1006/Mpat.1995.0047  0.407
1996 Ahmed R. Introduction: Immunity to viruses Seminars in Virology. 7: 93. DOI: 10.1006/Smvy.1996.0011  0.321
1995 Selvakumar R, Ahmed R, Wettstein FO. Tumor regression is associated with a specific immune response to the E2 protein of cottontail rabbit papillomavirus. Virology. 208: 298-302. PMID 11831711 DOI: 10.1006/Viro.1995.1152  0.305
1995 Asano MS, Ahmed R. Immune conflicts in lymphocytic choriomeningitis virus Springer Seminars in Immunopathology. 17: 247-259. PMID 8571171 DOI: 10.1007/Bf00196168  0.329
1995 Selvakumar R, Borenstein LA, Lin Y, Ahmed R, Wettstein FO. Immunization with Nonstructural Proteins E1 and E2 of Cottontail Rabbit Papillomavirus Stimulates Regression of Virus-Induced Papillomas Journal of Virology. 69: 602-605. PMID 7983764 DOI: 10.1128/Jvi.69.1.602-605.1995  0.343
1995 Villarete L, Fries Rd, Kolhekar S, Howard D, Ahmed R, Wu-Hsieh B. Impaired responsiveness to gamma interferon of macrophages infected with lymphocytic choriomeningitis virus clone 13: susceptibility to histoplasmosis. Infection and Immunity. 63: 1468-1472. PMID 7890411 DOI: 10.1128/Iai.63.4.1468-1472.1995  0.373
1995 Slifka MK, Matloubian M, Ahmed R. Bone marrow is a major site of long-term antibody production after acute viral infection. Journal of Virology. 69: 1895-902. PMID 7853531 DOI: 10.1128/Jvi.69.3.1895-1902.1995  0.374
1995 Shen H, Slifka MK, Matloubian M, Jensen ER, Ahmed R, Miller JF. Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity. Proceedings of the National Academy of Sciences of the United States of America. 92: 3987-91. PMID 7732018 DOI: 10.1073/Pnas.92.9.3987  0.537
1995 Clark WR, Walsh CM, Glass AA, Huang MTF, Ahmed R, Matloubian M. Cell-mediated cytotoxicity in perforin-less mice International Reviews of Immunology. 13: 1-14. PMID 7494105 DOI: 10.3109/08830189509061734  0.439
1995 Sher A, Ahmed R. Regulation of innate and adaptive responses to infection: new avenues and angles Current Opinion in Immunology. 7: 471-473. DOI: 10.1016/0952-7915(95)80090-5  0.311
1994 Selvakumar R, Borenstein LA, Lin Y, Ahmed R, Wettstein FO. T-cell response to cottontail rabbit papillomavirus structural proteins in infected rabbits. Journal of Virology. 68: 4043-4048. PMID 8189540 DOI: 10.1128/Jvi.68.6.4043-4048.1994  0.413
1994 Matloubian M, Concepcion RJ, Ahmed R. CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection. Journal of Virology. 68: 8056-63. PMID 7966595 DOI: 10.1128/Jvi.68.12.8056-8063.1994  0.57
1994 Villarete L, Somasundaram T, Ahmed R. Tissue-mediated selection of viral variants: correlation between glycoprotein mutation and growth in neuronal cells. Journal of Virology. 68: 7490-7496. PMID 7933132 DOI: 10.1128/Jvi.68.11.7490-7496.1994  0.341
1994 Walsh CM, Matloubian M, Liu CC, Ueda R, Kurahara CG, Christensen JL, Huang MT, Young JD, Ahmed R, Clark WR. Immune function in mice lacking the perforin gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 10854-8. PMID 7526382 DOI: 10.1073/Pnas.91.23.10854  0.498
1994 Lau LL, Jamieson BD, Somasundaram T, Ahmed R. Cytotoxic T-cell memory without antigen Nature. 369: 648-652. PMID 7516038 DOI: 10.1038/369648A0  0.547
1994 Ahmed R. Virus persistence and immune memory Seminars in Virology. 5: 319-324. DOI: 10.1006/Smvy.1994.1035  0.497
1993 Matloubian M, Kolhekar SR, Somasundaram T, Ahmed R. Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus. Journal of Virology. 67: 7340-9. PMID 7693969 DOI: 10.1128/Jvi.67.12.7340-7349.1993  0.322
1993 Lin Y, Borenstein LA, Selvakumar R, Ahmed R, Wettstein FO. Progression from papilloma to carcinoma is accompanied by changes in antibody response to papillomavirus proteins. Journal of Virology. 67: 382-389. PMID 7677955 DOI: 10.1128/Jvi.67.1.382-389.1993  0.311
1992 King CC, Jamieson BD, Reddy K, Bali N, Concepcion RJ, Ahmed R. Viral infection of the thymus. Journal of Virology. 66: 3155-60. PMID 1560541 DOI: 10.1128/Jvi.66.5.3155-3160.1992  0.587
1991 Ahmed R, Hahn CS, Somasundaram T, Villarete L, Matloubian M, Strauss JH. Molecular basis of organ-specific selection of viral variants during chronic infection. Journal of Virology. 65: 4242-7. PMID 2072451 DOI: 10.1128/Jvi.65.8.4242-4247.1991  0.377
1991 Tishon A, Salmi A, Ahmed R, Oldstone MB. Role of viral strains and host genes in determining levels of immune complexes in a model system: implications for HIV infection. Aids Research and Human Retroviruses. 7: 963-9. PMID 1812945 DOI: 10.1089/Aid.1991.7.963  0.552
1990 Oldstone MB, Ahmed R, Salvato M. Viruses as therapeutic agents. II. Viral reassortants map prevention of insulin-dependent diabetes mellitus to the small RNA of lymphocytic choriomeningitis virus. The Journal of Experimental Medicine. 171: 2091-100. PMID 2191074 DOI: 10.1084/Jem.171.6.2091  0.515
1990 King CC, De Fries R, Kolhekar SR, Ahmed R. In vivo selection of lymphocyte-tropic and macrophage-tropic variants of lymphocytic choriomeningitis virus during persistent infection Journal of Virology. 64: 5611-5616. PMID 1976825 DOI: 10.1128/Jvi.64.11.5611-5616.1990  0.438
1988 Wu-Hsieh B, Howard DH, Ahmed R. Virus-Induced Immunosuppression: A Murine Model of Susceptibility to Opportunistic Infection The Journal of Infectious Diseases. 158: 232-235. PMID 3392416 DOI: 10.1093/Infdis/158.1.232  0.364
1988 Ahmed R, Oldstone MB. Organ-specific selection of viral variants during chronic infection. The Journal of Experimental Medicine. 167: 1719-24. PMID 3367096 DOI: 10.1084/Jem.167.5.1719  0.569
1988 Ahmed R, Simon RS, Matloubian M, Kolhekar SR, Southern PJ, Freedman DM. Genetic analysis of in vivo-selected viral variants causing chronic infection: Importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus Journal of Virology. 62: 3301-3308. PMID 3261347 DOI: 10.1128/Jvi.62.9.3301-3308.1988  0.414
1988 Jamieson BD, Ahmed R. T-cell tolerance: exposure to virus in utero does not cause a permanent deletion of specific T cells Proceedings of the National Academy of Sciences of the United States of America. 85: 2265-2268. PMID 3258424 DOI: 10.1073/Pnas.85.7.2265  0.567
1988 Ahmed R, Butler LD, Bhatti L. T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses. Journal of Virology. 62: 2102-6. PMID 2966865 DOI: 10.1128/Jvi.62.6.2102-2106.1988  0.561
1988 Ahmed R, Jamieson BD. Curing of a chronic viral infection: Acquisition of T cell competence by a previously “tolerant” host Virus Research. 11: 63. DOI: 10.1016/0168-1702(88)90216-X  0.489
1987 Ahmed R, Jamieson BD, Porter DD. Immune therapy of a persistent and disseminated viral infection. Journal of Virology. 61: 3920-3929. PMID 3682061 DOI: 10.1128/Jvi.61.12.3920-3929.1987  0.413
1987 Jamieson BD, Butler LD, Ahmed R. Effective clearance of a persistent viral infection requires cooperation between virus-specific Lyt2+ T cells and nonspecific bone marrow-derived cells. Journal of Virology. 61: 3930-3937. PMID 3500329 DOI: 10.1128/Jvi.61.12.3930-3937.1987  0.512
1987 Ahmed R, King CC, Oldstone MBA. Virus-lymphocyte interaction: T cells of the helper subset are infected with lymphocytic choriomeningitis virus during persistent infection in vivo Journal of Virology. 61: 1571-1576. PMID 2952807 DOI: 10.1128/Jvi.61.5.1571-1576.1987  0.572
1986 Valsamakis V, Southern P, Blount P, Ahmed R, Buchmeier MJ, Oldstone MB. Dissecting the molecular anatomy of persistent infection with lymphocytic choriomeningitis virus. Medical Microbiology and Immunology. 175: 97-9. PMID 3724670 DOI: 10.1007/Bf02122424  0.389
1986 Riviere Y, Ahmed R, Oldstone MBA. The use of lymphocytic choriomeningitis virus reassortants to map viral genes causing virulence Medical Microbiology and Immunology. 175: 191-192. PMID 3724665 DOI: 10.1007/Bf02122448  0.34
1985 Riviere Y, Ahmed R, Southern P, Oldstone MB. Perturbation of differentiated functions during viral infection in vivo. II. Viral reassortants map growth hormone defect to the S RNA of the lymphocytic choriomeningitis virus genome. Virology. 142: 175-82. PMID 4060570 DOI: 10.1016/0042-6822(85)90431-3  0.495
1985 Riviere Y, Ahmed R, Southern PJ, Buchmeier MJ, Dutko FJ, Oldstone MB. The S RNA segment of lymphocytic choriomeningitis virus codes for the nucleoprotein and glycoproteins 1 and 2 Journal of Virology. 53: 966-968. PMID 3973970 DOI: 10.1128/Jvi.53.3.966-968.1985  0.46
1985 Oldstone MB, Ahmed R, Byrne J, Buchmeier MJ, Riviere Y, Southern P. Virus and immune responses: lymphocytic choriomeningitis virus as a prototype model of viral pathogenesis. British Medical Bulletin. 41: 70-4. PMID 3882190 DOI: 10.1093/Oxfordjournals.Bmb.A072029  0.536
1985 Oldstone MB, Ahmed R, Buchmeier MJ, Blount P, Tishon A. Perturbation of differentiated functions during viral infection in vivo. I. Relationship of lymphocytic choriomeningitis virus and host strains to growth hormone deficiency. Virology. 142: 158-74. PMID 2414901 DOI: 10.1016/0042-6822(85)90430-1  0.536
1985 Oldstone MB, Southern P, Riviere Y, Ahmed R. Mapping and altering lymphocytic choriomeningitis viral gene expression during persistent infection Virus Research. 3: 66. DOI: 10.1016/0168-1702(85)90384-3  0.506
1984 Ahmed R, Byrne JA, Oldstone MBA. Virus specificity of cytotoxic T lymphocytes generated during acute lymphocytic choriomeningitis virus infection: Role of the H-2 region in determining cross-reactivity for different lymphocytic choriomeningitis virus strains Journal of Virology. 51: 34-41. PMID 6610062 DOI: 10.1128/Jvi.51.1.34-41.1984  0.405
1984 Ahmed R, Salmi A, Butler LD, Chiller JM, Oldstone MB. Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence. The Journal of Experimental Medicine. 160: 521-40. PMID 6332167 DOI: 10.1084/Jem.160.2.521  0.619
1983 Ahmed R, Kauffman RS, Fields BN. Genetic variation during persistent reovirus infection: Isolation of cold-sensitive and temperature-sensitive mutants from persistently infected L cells Virology. 131: 71-78. PMID 6649415 DOI: 10.1016/0042-6822(83)90534-2  0.603
1981 Ahmed R, Fields BN. Reassortment of genome segments between reovirus defective interfering particles and infectious virus: construction of temperature-sensitive and attenuated viruses by rescue of mutations from DI particles. Virology. 111: 351-363. PMID 7245608 DOI: 10.1016/0042-6822(81)90339-1  0.527
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