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A Berghuis - Publications

Affiliations: 
McMaster University, Hamilton, ON, Canada 
Area:
Biochemistry
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Zieliński M, Blanchet J, Hailemariam S, Berghuis AM. Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One. 17: e0269684. PMID 35921328 DOI: 10.1371/journal.pone.0269684  0.334
2016 Baettig OM, Shi K, Yachnin BJ, Burk DL, Berghuis AM. Comprehensive characterization of ligand-induced plasticity changes in a dimeric enzyme. The Febs Journal. PMID 27333541 DOI: 10.1111/Febs.13788  0.316
2014 Park J, Lin YS, Tsantrizos YS, Berghuis AM. Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate. Acta Crystallographica. Section F, Structural Biology Communications. 70: 299-304. PMID 24598914 DOI: 10.1107/S2053230X14002106  0.323
2014 Yachnin B, McEvoy M, MacCuish R, Morley K, Mittermaier A, Lau P, Berghuis A. The Structural Basis for BVMO Substrate Profile and Stereospecificity Acta Crystallographica Section a Foundations and Advances. 70: C485-C485. DOI: 10.1107/S205327331409514X  0.369
2014 Bassenden A, Rodionov D, Sabet-Kassouf N, Haji T, Shi K, Berghuis A. "Structural characterization of aminoglycoside modifying enzyme ANT(2"")-Ia" Acta Crystallographica Section a Foundations and Advances. 70: C702-C702. DOI: 10.1107/S2053273314092973  0.303
2014 Rodionov D, Marks D, Romero P, Berghuis A. Crystal structure of an alleged mannosylphosphate transferase Ktr6p at 3.06 Å Acta Crystallographica Section a Foundations and Advances. 70: C1671-C1671. DOI: 10.1107/S2053273314083284  0.364
2012 Park J, Lin YS, De Schutter JW, Tsantrizos YS, Berghuis AM. Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Structural Biology. 12: 32. PMID 23234314 DOI: 10.1186/1472-6807-12-32  0.311
2012 Yachnin BJ, Sprules T, McEvoy MB, Lau PC, Berghuis AM. The substrate-bound crystal structure of a Baeyer-Villiger monooxygenase exhibits a Criegee-like conformation. Journal of the American Chemical Society. 134: 7788-95. PMID 22506764 DOI: 10.1021/ja211876p  0.318
2012 Shi K, Berghuis AM. Structural basis for dual nucleotide selectivity of aminoglycoside 2''-phosphotransferase IVa provides insight on determinants of nucleotide specificity of aminoglycoside kinases. The Journal of Biological Chemistry. 287: 13094-102. PMID 22371504 DOI: 10.1074/jbc.M112.349670  0.324
2011 Yachnin BJ, Colin DY, Volpato JP, Ebert M, Pelletier JN, Berghuis AM. Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67: 1316-1322. PMID 22102224 DOI: 10.1107/S1744309111030417  0.344
2011 Shi K, Houston DR, Berghuis AM. Crystal structures of antibiotic-bound complexes of aminoglycoside 2''-phosphotransferase IVa highlight the diversity in substrate binding modes among aminoglycoside kinases. Biochemistry. 50: 6237-44. PMID 21678960 DOI: 10.1021/bi200747f  0.34
2010 Fong DH, Lemke CT, Hwang J, Xiong B, Berghuis AM. Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila. The Journal of Biological Chemistry. 285: 9545-55. PMID 20089863 DOI: 10.1074/jbc.M109.038364  0.326
2009 Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN. Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance Journal of Biological Chemistry. 284: 20079-20089. PMID 19478082 DOI: 10.1074/Jbc.M109.018010  0.309
2007 Burk DL, Hwang J, Kwok E, Marrone L, Goodfellow V, Dmitrienko GI, Berghuis AM. Structural studies of the final enzyme in the alpha-aminoadipate pathway-saccharopine dehydrogenase from Saccharomyces cerevisiae. Journal of Molecular Biology. 373: 745-54. PMID 17854830 DOI: 10.1016/J.Jmb.2007.08.044  0.329
2006 Fong DH, Yim VCN, D'Elia MA, Brown ED, Berghuis AM. Crystal structure of CTP:glycerol-3-phosphate cytidylyltransferase from Staphylococcus aureus: Examination of structural basis for kinetic mechanism Biochimica Et Biophysica Acta - Proteins and Proteomics. 1764: 63-69. PMID 16344011 DOI: 10.1016/j.bbapap.2005.10.015  0.357
2005 Lemke CT, Hwang J, Xiong B, Cianciotto NP, Berghuis AM. Crystallization and preliminary crystallographic analysis of an aminoglycoside kinase from Legionella pneumophila. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 606-8. PMID 16511108 DOI: 10.1107/S1744309105016301  0.346
2005 Mirza IA, Nazi I, Korczynska M, Wright GD, Berghuis AM. Crystal structure of homoserine transacetylase from Haemophilus influenzae reveals a new family of α/β-hydrolases Biochemistry. 44: 15768-15773. PMID 16313180 DOI: 10.1021/Bi051951Y  0.32
2005 Burk DL, Xiong B, Breitbach C, Berghuis AM. Structures of aminoglycoside acetyltransferase AAC(6')-Ii in a novel crystal form: structural and normal-mode analyses. Acta Crystallographica. Section D, Biological Crystallography. 61: 1273-9. PMID 16131761 DOI: 10.1107/S0907444905021487  0.343
2004 Ejim L, Mirza IA, Capone C, Nazi I, Jenkins S, Chee GL, Berghuis AM, Wright GD. New phenolic inhibitors of yeast homoserine dehydrogenase. Bioorganic & Medicinal Chemistry. 12: 3825-30. PMID 15210149 DOI: 10.1016/J.Bmc.2004.05.009  0.319
2003 Jacques SL, Mirza IA, Ejim L, Koteva K, Hughes DW, Green K, Kinach R, Honek JF, Lai HK, Berghuis AM, Wright GD. Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase. Chemistry & Biology. 10: 989-95. PMID 14583265 DOI: 10.1016/J.Chembiol.2003.09.015  0.311
2001 Yim VCN, Zolli M, Badurina DS, Rossi L, Brown ED, Berghuis AM. Crystallization and preliminary X-ray diffraction studies of glycerol 3-phosphate cytidylyltransferase from Staphylococcus aureus Acta Crystallographica Section D: Biological Crystallography. 57: 918-920. PMID 11375529 DOI: 10.1107/S0907444901005212  0.348
2001 Leung AK, Duewel HS, Honek JF, Berghuis AM. Crystal structure of the lytic transglycosylase from bacteriophage lambda in complex with hexa-N-acetylchitohexaose. Biochemistry. 40: 5665-73. PMID 11341831 DOI: 10.1021/Bi0028035  0.31
2000 DeLaBarre B, Thompson PR, Wright GD, Berghuis AM. Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases. Nature Structural Biology. 7: 238-44. PMID 10700284 DOI: 10.1038/73359  0.533
1999 Wybenga-Groot LE, Draker Ka, Wright GD, Berghuis AM. Crystal structure of an aminoglycoside 6'-N-acetyltransferase: Defining the GCN5-related N-acetyltransferase superfamily fold Structure. 7: 497-507. PMID 10378269 DOI: 10.1016/S0969-2126(99)80066-5  0.309
1998 DeLaBarre B, Jacques SL, Pratt CE, Ruth DA, Wright GD, Berghuis AM. Crystallization and preliminary X-ray diffraction studies of homoserine dehydrogenase from Saccharomyces cerevisiae. Acta Crystallographica. Section D, Biological Crystallography. 54: 413-5. PMID 9761913 DOI: 10.1107/S0907444997011967  0.519
1996 DeLaBarre B, Wright GD, Berghuis AM. Crystallographic studies of homoserine dehydrogenase for the design of novel antifungal agents Acta Crystallographica Section a Foundations of Crystallography. 52: C99-C99. DOI: 10.1107/S0108767396095153  0.501
1994 Coleman DE, Lee E, Mixon MB, Linder ME, Berghuis AM, Gilman AG, Sprang SR. Crystallization and preliminary crystallographic studies of Gi alpha 1 and mutants of Gi alpha 1 in the GTP and GDP-bound states. Journal of Molecular Biology. 238: 630-4. PMID 8176751 DOI: 10.1006/Jmbi.1994.1320  0.315
1993 Burk D, Wang Y, Dombroski D, Berghuis AM, Evans SV, Luo Y, Withers SG, Brayer GD. Isolation, crystallization and preliminary diffraction analyses of human pancreatic alpha-amylase. Journal of Molecular Biology. 230: 1084-5. PMID 8478920 DOI: 10.1006/Jmbi.1993.1221  0.312
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