Maurine Linder - Publications

Washington University, Saint Louis, St. Louis, MO 
Molecular Biology, Biochemistry

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Hilgemann DW, Fine M, Linder ME, Jennings BC, Lin MJ. Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts. Elife. 2: e01293. PMID 24282236 DOI: 10.7554/Elife.01293  1
2013 Linder ME, Jennings BC. Mechanism and function of DHHC S-acyltransferases. Biochemical Society Transactions. 41: 29-34. PMID 23356254 DOI: 10.1042/Bst20120328  1
2012 Jennings BC, Linder ME. DHHC protein S-acyltransferases use similar ping-pong kinetic mechanisms but display different acyl-CoA specificities. The Journal of Biological Chemistry. 287: 7236-45. PMID 22247542 DOI: 10.1074/Jbc.M111.337246  1
2011 Jia L, Linder ME, Blumer KJ. Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein. The Journal of Biological Chemistry. 286: 13695-703. PMID 21343290 DOI: 10.1074/Jbc.M110.193763  1
2011 Ahearn IM, Tsai FD, Court H, Zhou M, Jennings BC, Ahmed M, Fehrenbacher N, Linder ME, Philips MR. FKBP12 binds to acylated H-ras and promotes depalmitoylation. Molecular Cell. 41: 173-85. PMID 21255728 DOI: 10.1016/J.Molcel.2011.01.001  1
2010 Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E. Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity. Science Signaling. 3: ra37. PMID 20460648 DOI: 10.1126/Scisignal.2000647  1
2010 Jennings BC, Linder ME. Regulation of g proteins by covalent modification Handbook of Cell Signaling, 2/E. 2: 1629-1633. DOI: 10.1016/B978-0-12-374145-5.00200-X  1
2010 Linder ME. Lipid-mediated localization of signaling proteins Handbook of Cell Signaling, 2/E. 1: 365-371. DOI: 10.1016/B978-0-12-374145-5.00053-X  1
2009 Nadolski MJ, Linder ME. Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3. The Journal of Biological Chemistry. 284: 17720-30. PMID 19416974 DOI: 10.1074/Jbc.M109.005447  1
2009 Jennings BC, Nadolski MJ, Ling Y, Baker MB, Harrison ML, Deschenes RJ, Linder ME. 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro. Journal of Lipid Research. 50: 233-42. PMID 18827284 DOI: 10.1194/Jlr.M800270-Jlr200  1
2008 Linder ME. Neuroscience: greasy proteins of the neuron. Nature. 456: 887-8. PMID 19092922 DOI: 10.1038/456887a  1
2007 Nadolski MJ, Linder ME. Protein lipidation. The Febs Journal. 274: 5202-10. PMID 17892486 DOI: 10.1111/J.1742-4658.2007.06056.X  1
2007 Linder ME, Deschenes RJ. Palmitoylation: policing protein stability and traffic. Nature Reviews. Molecular Cell Biology. 8: 74-84. PMID 17183362 DOI: 10.1038/Nrm2084  1
2006 Budde C, Schoenfish MJ, Linder ME, Deschenes RJ. Purification and characterization of recombinant protein acyltransferases. Methods (San Diego, Calif.). 40: 143-50. PMID 17012026 DOI: 10.1016/J.Ymeth.2006.07.017  1
2006 Linder M, Deschenes R. Protein palmitoylation. Methods (San Diego, Calif.). 40: 125-6. PMID 17012023 DOI: 10.1016/j.ymeth.2006.08.014  1
2006 Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ. R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism. The Journal of Biological Chemistry. 281: 28222-31. PMID 16867977 DOI: 10.1074/Jbc.M604428200  1
2006 Mitchell DA, Vasudevan A, Linder ME, Deschenes RJ. Protein palmitoylation by a family of DHHC protein S-acyltransferases. Journal of Lipid Research. 47: 1118-27. PMID 16582420 DOI: 10.1194/Jlr.R600007-Jlr200  1
2006 Mittal V, Linder ME. Biochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A. The Biochemical Journal. 394: 309-15. PMID 16246175 DOI: 10.1042/Bj20051086  1
2005 Smotrys JE, Schoenfish MJ, Stutz MA, Linder ME. The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p. The Journal of Cell Biology. 170: 1091-9. PMID 16186255 DOI: 10.1083/Jcb.200507048  1
2005 Swarthout JT, Lobo S, Farh L, Croke MR, Greentree WK, Deschenes RJ, Linder ME. DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras. The Journal of Biological Chemistry. 280: 31141-8. PMID 16000296 DOI: 10.1074/Jbc.M504113200  1
2005 Drenan RM, Doupnik CA, Boyle MP, Muglia LJ, Huettner JE, Linder ME, Blumer KJ. Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family. The Journal of Cell Biology. 169: 623-33. PMID 15897264 DOI: 10.1083/Jcb.200502007  1
2004 Mittal V, Linder ME. The RGS14 GoLoco domain discriminates among Galphai isoforms. The Journal of Biological Chemistry. 279: 46772-8. PMID 15337739 DOI: 10.1074/Jbc.M407409200  1
2004 Embry AC, Glick JL, Linder ME, Casey PJ. Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family. Molecular Pharmacology. 66: 1325-31. PMID 15308761 DOI: 10.1124/Mol.104.004093  1
2004 Smotrys JE, Linder ME. Palmitoylation of intracellular signaling proteins: regulation and function. Annual Review of Biochemistry. 73: 559-87. PMID 15189153 DOI: 10.1146/Annurev.Biochem.73.011303.073954  1
2004 Linder ME, Deschenes RJ. Model organisms lead the way to protein palmitoyltransferases. Journal of Cell Science. 117: 521-6. PMID 14730009 DOI: 10.1242/Jcs.00989  1
2004 Bernstein LS, Linder ME, Hepler JR. Analysis of RGS protein palmitoylation. Methods in Molecular Biology (Clifton, N.J.). 237: 195-204. PMID 14501051 DOI: 10.1385/1-59259-430-1:195  1
2004 Greentree WK, Linder ME. Purification of recombinant G protein alpha subunits from Escherichia coli. Methods in Molecular Biology (Clifton, N.J.). 237: 3-20. PMID 14501035 DOI: 10.1385/1-59259-430-1:3  1
2003 Linder ME, Deschenes RJ. New insights into the mechanisms of protein palmitoylation. Biochemistry. 42: 4311-20. PMID 12693927 DOI: 10.1021/Bi034159A  1
2002 Lobo S, Greentree WK, Linder ME, Deschenes RJ. Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 277: 41268-73. PMID 12193598 DOI: 10.1074/Jbc.M206573200  1
2002 Mirshahi T, Mittal V, Zhang H, Linder ME, Logothetis DE. Distinct sites on G protein beta gamma subunits regulate different effector functions. The Journal of Biological Chemistry. 277: 36345-50. PMID 12124391 DOI: 10.1074/Jbc.M205359200  1
2002 Loranger SS, Linder ME. SNAP-25 traffics to the plasma membrane by a syntaxin-independent mechanism. The Journal of Biological Chemistry. 277: 34303-9. PMID 12114505 DOI: 10.1074/Jbc.M202125200  1
2001 Fogg VC, Azpiazu I, Linder ME, Smrcka A, Scarlata S, Gautam N. Role of the gamma subunit prenyl moiety in G protein beta gamma complex interaction with phospholipase Cbeta. The Journal of Biological Chemistry. 276: 41797-802. PMID 11546822 DOI: 10.1074/Jbc.M107661200  1
2001 Fawzi AB, Macdonald D, Benbow LL, Smith-Torhan A, Zhang H, Weig BC, Ho G, Tulshian D, Linder ME, Graziano MP. SCH-202676: An allosteric modulator of both agonist and antagonist binding to G protein-coupled receptors. Molecular Pharmacology. 59: 30-7. PMID 11125021 DOI: 10.1124/mol.59.1.30  0.32
2001 Linder ME. 8 Reversible modification of proteins with thioester-linked fatty acids Enzymes. 21: 215-240. DOI: 10.1016/S1874-6047(01)80021-4  1
2000 Dunphy JT, Schroeder H, Leventis R, Greentree WK, Knudsen JK, Silvius JR, Linder ME. Differential effects of acyl-CoA binding protein on enzymatic and non- enzymatic thioacylation of protein and peptide substrates Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1485: 185-198. PMID 10832099 DOI: 10.1016/S1388-1981(00)00060-3  1
2000 Bernstein LS, Grillo AA, Loranger SS, Linder ME. RGS4 binds to membranes through an amphipathic alpha -helix. The Journal of Biological Chemistry. 275: 18520-6. PMID 10764749 DOI: 10.1074/Jbc.M000618200  1
2000 Manahan CL, Patnana M, Blumer KJ, Linder ME. Dual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae. Molecular Biology of the Cell. 11: 957-68. PMID 10712512 DOI: 10.1091/Mbc.11.3.957  1
2000 Moffett S, Brown DA, Linder ME. Lipid-dependent targeting of G proteins into rafts. The Journal of Biological Chemistry. 275: 2191-8. PMID 10636925 DOI: 10.1074/jbc.275.3.2191  1
1999 Heximer SP, Srinivasa SP, Bernstein LS, Bernard JL, Linder ME, Hepler JR, Blumer KJ. G protein selectivity is a determinant of RGS2 function. The Journal of Biological Chemistry. 274: 34253-9. PMID 10567399 DOI: 10.1074/Jbc.274.48.34253  1
1999 Gonzalo S, Greentree WK, Linder ME. SNAP-25 is targeted to the plasma membrane through a novel membrane- binding domain Journal of Biological Chemistry. 274: 21313-21318. PMID 10409690 DOI: 10.1074/Jbc.274.30.21313  1
1999 Frazier WA, Gao AG, Dimitry J, Chung J, Brown EJ, Lindberg FP, Linder ME. The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi. The Journal of Biological Chemistry. 274: 8554-60. PMID 10085089 DOI: 10.1074/Jbc.274.13.8554  1
1998 Dunphy JT, Linder ME. Signalling functions of protein palmitoylation Biochimica Et Biophysica Acta - Lipids and Lipid Metabolism. 1436: 245-261. PMID 9838145 DOI: 10.1016/S0005-2760(98)00130-1  1
1998 Srinivasa SP, Bernstein LS, Blumer KJ, Linder ME. Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 95: 5584-9. PMID 9576926 DOI: 10.1073/Pnas.95.10.5584  1
1998 Gonzalo S, Linder ME. SNAP-25 palmitoylation and plasma membrane targeting require a functional secretory pathway Molecular Biology of the Cell. 9: 585-597. PMID 9487128 DOI: 10.1091/Mbc.9.3.585  1
1997 Heximer SP, Watson N, Linder ME, Blumer KJ, Hepler JR. RGS2/G0S8 is a selective inhibitor of Gqalpha function. Proceedings of the National Academy of Sciences of the United States of America. 94: 14389-93. PMID 9405622 DOI: 10.1073/Pnas.94.26.14389  1
1997 Linder ME, Gonzalo S. Palmitoylation of SNAP-25 is required for membrane targeting but not stable membrane association Faseb Journal. 11.  1
1996 Cohen NA, Sha Q, Makhina EN, Lopatin AN, Linder ME, Snyder SH, Nichols CG. Inhibition of an inward rectifier potassium channel (Kir2.3) by G-protein betagamma subunits. The Journal of Biological Chemistry. 271: 32301-5. PMID 8943291 DOI: 10.1074/Jbc.271.50.32301  1
1996 Miller BA, Bell L, Hansen CA, Robishaw JD, Linder ME, Cheung JY. G-protein alpha subunit Gi(alpha)2 mediates erythropoietin signal transduction in human erythroid precursors. The Journal of Clinical Investigation. 98: 1728-36. PMID 8878422 DOI: 10.1172/JCI118971  1
1996 Watson N, Linder ME, Druey KM, Kehrl JH, Blumer KJ. RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature. 383: 172-5. PMID 8774882 DOI: 10.1038/383172A0  1
1995 Moyers JS, Linder ME, Shannon JD, Parsons SJ. Identification of the in vitro phosphorylation sites on G(sα) mediated by pp60(c-src) Biochemical Journal. 305: 411-417. PMID 7530445 DOI: 10.1042/Bj3050411  1
1994 Fields TA, Linder ME, Casey PJ. Subtype-specific binding of azidoanilido-GTP by purified G protein α subunits Biochemistry. 33: 6877-6883. PMID 8204622 DOI: 10.1021/Bi00188A017  1
1994 Coleman DE, Lee E, Mixon MB, Linder ME, Berghuis AM, Gilman AG, Sprang SR. Crystallization and preliminary crystallographic studies of Gi alpha 1 and mutants of Gi alpha 1 in the GTP and GDP-bound states. Journal of Molecular Biology. 238: 630-4. PMID 8176751 DOI: 10.1006/Jmbi.1994.1320  1
1994 Wickman KD, Iñiguez-Lluhl JA, Davenport PA, Taussig R, Krapivinsky GB, Linder ME, Gilman AG, Clapham DE. Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel. Nature. 368: 255-7. PMID 8145826 DOI: 10.1038/368255A0  1
1994 Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, Sprang SR. Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. Science (New York, N.Y.). 265: 1405-12. PMID 8073283 DOI: 10.1126/Science.8073283  1
1994 Mumby SM, Linder ME. [20] Myristoylation of G-protein α subunits Methods in Enzymology. 237: 254-268. PMID 7935001 DOI: 10.1016/S0076-6879(94)37067-2  1
1994 Lee E, Linder ME, Gilman AG. [12] Expression of G-protein α subunits in Escherichia coli Methods in Enzymology. 237: 146-154. PMID 7934993 DOI: 10.1016/S0076-6879(94)37059-1  1
1993 Linder ME, Middleton P, Hepler JR, Taussig R, Gilman AG, Mumby SM. Lipid modifications of G proteins: alpha subunits are palmitoylated. Proceedings of the National Academy of Sciences of the United States of America. 90: 3675-9. PMID 8475115 DOI: 10.1073/Pnas.90.8.3675  1
1992 Linder ME, Gilman AG. G proteins. Scientific American. 267: 56-61, 64-5. PMID 1502510  1
1992 Hepler JR, Gilman AG. G proteins. Trends in Biochemical Sciences. 17: 383-7. PMID 1455506 DOI: 10.1016/0968-0004(92)90005-T  0.96
1992 Hausdorff WP, Pitcher JA, Luttrell DK, Linder ME, Kurose H, Parsons SJ, Caron MG, Lefkowitz RJ. Tyrosine phosphorylation of G protein α subunits by pp60c-src Proceedings of the National Academy of Sciences of the United States of America. 89: 5720-5724. PMID 1378615 DOI: 10.1073/Pnas.89.13.5720  1
1991 Linder ME, Gilman AG. Purification of recombinant Gi alpha and Go alpha proteins from Escherichia coli. Methods in Enzymology. 195: 202-15. PMID 1903487 DOI: 10.1016/0076-6879(91)95167-I  1
1991 Rubenstein RC, Linder ME, Ross EM. Selectivity of the beta-adrenergic receptor among Gs, Gi's, and Go: assay using recombinant alpha subunits in reconstituted phospholipid vesicles. Biochemistry. 30: 10769-77. PMID 1657154 DOI: 10.1021/Bi00108A023  1
1990 Duronio RJ, Rudnick DA, Johnson RL, Linder ME, Gordon JI. Reconstitution of protein N-myristoylation in Escherichia coli Methods. 1: 253-263. DOI: 10.1016/S1046-2023(05)80325-1  1
1988 Linder ME, Burr JG. Immunological characterization of proteins detected by phosphotyrosine antibodies in cells transformed by Rous sarcoma virus Journal of Virology. 62: 2665-2673. PMID 2455815  1
1988 Linder ME, Burr JG. Nonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 85: 2608-2612. PMID 2451829 DOI: 10.1073/pnas.85.8.2608  1
1986 Cobb MH, Burr JG, Linder ME, Gray TB, Gregory JS. A similar ribosomal protein S6 kinase activity is found in insulin-treated 3T3-L1 cells and chick embryo fibroblasts transformed by Rous sarcoma virus Biochemical and Biophysical Research Communications. 137: 702-708. PMID 3015127 DOI: 10.1016/0006-291X(86)91135-6  1
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