Patricia Cohen - Publications

Affiliations: 
Biochemistry University of Dundee, Dundee, Scotland, United Kingdom 
Website:
http://www.ppu.mrc.ac.uk/research/?pid=4&sub1=past_lab

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zeke T, Morrice N, Vázquez-Martin C, Cohen PTW. Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole. The Biochemical Journal. 478: 4025. PMID 34813651 DOI: 10.1042/BJ20040690_EOC  0.375
2013 Voss M, Campbell K, Saranzewa N, Campbell DG, Hastie CJ, Peggie MW, Martin-Granados C, Prescott AR, Cohen PT. Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with γ-tubulin. Cell Cycle (Georgetown, Tex.). 12: 2876-87. PMID 23966160 DOI: 10.4161/cc.25919  0.303
2011 Kelsall IR, Voss M, Munro S, Cuthbertson DJ, Cohen PT. R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signals. Journal of Neurochemistry. 118: 596-610. PMID 21668450 DOI: 10.1111/j.1471-4159.2011.07345.x  0.377
2011 Fardilha M, Esteves SL, Korrodi-Gregório L, Vintém AP, Domingues SC, Rebelo S, Morrice N, Cohen PT, da Cruz e Silva OA, da Cruz e Silva EF. Identification of the human testis protein phosphatase 1 interactome. Biochemical Pharmacology. 82: 1403-15. PMID 21382349 DOI: 10.1016/J.Bcp.2011.02.018  0.577
2011 Voss M, Paterson J, Kelsall IR, Martín-Granados C, Hastie CJ, Peggie MW, Cohen PT. Ppm1E is an in cellulo AMP-activated protein kinase phosphatase. Cellular Signalling. 23: 114-24. PMID 20801214 DOI: 10.1016/j.cellsig.2010.08.010  0.409
2007 Browne GJ, Fardilha M, Oxenham SK, Wu W, Helps NR, da Cruz E Silva OA, Cohen PT, da Cruz E Silva EF. SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein. The Biochemical Journal. 402: 187-96. PMID 17123353 DOI: 10.1042/Bj20060600  0.664
2005 Hastie CJ, Borthwick EB, Morrison LF, Codd GA, Cohen PT. Inhibition of several protein phosphatases by a non-covalently interacting microcystin and a novel cyanobacterial peptide, nostocyclin. Biochimica Et Biophysica Acta. 1726: 187-93. PMID 16046071 DOI: 10.1016/j.bbagen.2005.06.005  0.398
2005 Cohen PT, Philp A, Vázquez-Martin C. Protein phosphatase 4--from obscurity to vital functions. Febs Letters. 579: 3278-86. PMID 15913612 DOI: 10.1016/j.febslet.2005.04.070  0.35
2005 Zeke T, Morrice N, Vázquez-Martin C, Cohen PT. Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole. The Biochemical Journal. 385: 45-56. PMID 15383005 DOI: 10.1042/BJ20040690  0.402
2005 Cohen PTW, Cohen P, Brustel YLM. Regulation of glycogen phosphorylase and glycogen synthase by adrenalin in soleus muscle of phosphorylase-kinase-deficient mice. Febs Journal. 115: 619-625. PMID 6786887 DOI: 10.1111/J.1432-1033.1981.Tb06247.X  0.361
2003 Cohen PT, Browne GJ, Delibegovic M, Munro S. Assay of protein phosphatase 1 complexes. Methods in Enzymology. 366: 135-44. PMID 14674246 DOI: 10.1016/S0076-6879(03)66012-X  0.406
2003 Carnegie GK, Sleeman JE, Morrice N, Hastie CJ, Peggie MW, Philp A, Lamond AI, Cohen PT. Protein phosphatase 4 interacts with the Survival of Motor Neurons complex and enhances the temporal localisation of snRNPs. Journal of Cell Science. 116: 1905-13. PMID 12668731 DOI: 10.1242/jcs.00409  0.422
2002 Cohen PT. Protein phosphatase 1--targeted in many directions. Journal of Cell Science. 115: 241-56. PMID 11839776 DOI: 10.1242/jcs.115.2.241  0.481
2001 Cohen P. The role of protein phosphorylation in human health and disease. The Sir Hans Krebs Medal Lecture. European Journal of Biochemistry. 268: 5001-10. PMID 11589691 DOI: 10.1046/J.0014-2956.2001.02473.X  0.453
2001 Cohen P. The regulation of protein function by multisite phosphorylation--a 25 year update. Trends in Biochemical Sciences. 25: 596-601. PMID 11116185 DOI: 10.1016/S0968-0004(00)01712-6  0.5
1999 Cohen P. The development and therapeutic potential of protein kinase inhibitors. Current Opinion in Chemical Biology. 3: 459-65. PMID 10419844 DOI: 10.1016/S1367-5931(99)80067-2  0.36
1998 Cohen P, Goedert M. Engineering protein kinases with distinct nucleotide specificities and inhibitor sensitivities by mutation of a single amino acid. Chemistry & Biology. 5: R161-4. PMID 9662509 DOI: 10.1016/S1074-5521(98)90068-0  0.357
1997 Egloff MP, Johnson DF, Moorhead G, Cohen PT, Cohen P, Barford D. Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1. The Embo Journal. 16: 1876-87. PMID 9155014 DOI: 10.1093/Emboj/16.8.1876  0.443
1997 Johnson D, Cohen P, Chen MX, Chen YH, Cohen PT. Identification of the regions on the M110 subunit of protein phosphatase 1M that interact with the M21 subunit and with myosin. European Journal of Biochemistry / Febs. 244: 931-9. PMID 9108268 DOI: 10.1111/J.1432-1033.1997.00931.X  0.301
1996 MacKintosh C, Garton AJ, McDonnell A, Barford D, Cohen PT, Tonks NK, Cohen P. Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation. Febs Letters. 397: 235-8. PMID 8955354 DOI: 10.1016/S0014-5793(96)01175-1  0.506
1996 Cohen PTW, Chen MX, Armstrong CG. Novel Protein Phosphatases That May Participate in Cell Signaling Advances in Pharmacology. 36: 67-89. PMID 8783555 DOI: 10.1016/S1054-3589(08)60577-3  0.34
1996 Johnson DF, Moorhead G, Caudwell FB, Cohen P, Chen YH, Chen MX, Cohen PT. Identification of protein-phosphatase-1-binding domains on the glycogen and myofibrillar targetting subunits. European Journal of Biochemistry / Febs. 239: 317-25. PMID 8706735 DOI: 10.1111/J.1432-1033.1996.0317U.X  0.366
1995 Goedert M, Jakes R, Qi Z, Wang JH, Cohen P. Protein phosphatase 2A is the major enzyme in brain that dephosphorylates tau protein phosphorylated by proline-directed protein kinases or cyclic AMP-dependent protein kinase. Journal of Neurochemistry. 65: 2804-7. PMID 7595582 DOI: 10.1046/J.1471-4159.1995.65062804.X  0.532
1995 Goedert M, Spillantini MG, Jakes R, Crowther RA, Vanmechelen E, Probst A, Götz J, Bürki K, Cohen P. Molecular dissection of the paired helical filament. Neurobiology of Aging. 16: 325-34. PMID 7566342 DOI: 10.1016/0197-4580(95)00017-9  0.493
1995 MacKintosh RW, Dalby KN, Campbell DG, Cohen PT, Cohen P, MacKintosh C. The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1. Febs Letters. 371: 236-40. PMID 7556599 DOI: 10.1016/0014-5793(95)00888-G  0.49
1995 Leighton IA, Dalby KN, Caudwell FB, Cohen PT, Cohen P. Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation. Febs Letters. 375: 289-93. PMID 7498520 DOI: 10.1016/0014-5793(95)01170-J  0.337
1994 Goedert M, Jakes R, Crowther RA, Cohen P, Vanmechelen E, Vandermeeren M, Cras P. Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. The Biochemical Journal. 301: 871-7. PMID 7519852 DOI: 10.1042/Bj3010871  0.342
1994 Alessi D, Saito Y, Campbell D, Cohen P, Sithanandam G, Rapp U, Ashworth A, Marshall C, Cowley S. Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1. The Embo Journal. 13: 1610-1619. DOI: 10.1002/J.1460-2075.1994.Tb06424.X  0.408
1993 Sutherland C, Leighton IA, Cohen P. Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling. The Biochemical Journal. 15-9. PMID 8250835 DOI: 10.1042/Bj2960015  0.424
1992 Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL. Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry. 31: 3896-901. PMID 1373650 DOI: 10.1021/Bi00131A002  0.418
1992 Traverse S, Gomez N, Paterson H, Marshall C, Cohen P. Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochemical Journal. 288: 351-355. PMID 1334404 DOI: 10.1042/Bj2880351  0.346
1992 Stokoe D, Campbell DG, Nakielny S, Hidaka H, Leevers SJ, Marshall C, Cohen P. MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase. The Embo Journal. 11: 3985-3994. DOI: 10.1002/J.1460-2075.1992.Tb05492.X  0.44
1991 MacKintosh C, Coggins J, Cohen P. Plant protein phosphatases. Subcellular distribution, detection of protein phosphatase 2C and identification of protein phosphatase 2A as the major quinate dehydrogenase phosphatase. The Biochemical Journal. 273: 733-8. PMID 1847622 DOI: 10.1042/Bj2730733  0.461
1989 Haystead TA, Sim AT, Carling D, Honnor RC, Tsukitani Y, Cohen P, Hardie DG. Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism. Nature. 337: 78-81. PMID 2562908 DOI: 10.1038/337078A0  0.507
1989 MacKintosh C, Cohen P. Identification of high levels of type 1 and type 2A protein phosphatases in higher plants. The Biochemical Journal. 262: 335-9. PMID 2554892 DOI: 10.1042/Bj2620335  0.361
1989 Cohen PTW, Cohen P. Discovery of a protein phosphatase activity encoded in the genome of bacteriophage lambda. Probable identity with open reading frame 221. Biochemical Journal. 260: 931-934. PMID 2548489 DOI: 10.1042/Bj2600931  0.538
1989 Cohen PT, Schelling DL, da Cruz e Silva OB, Barker HM, Cohen P. The major type-1 protein phosphatase catalytic subunits are the same gene products in rabbit skeletal muscle and rabbit liver. Biochimica Et Biophysica Acta. 1008: 125-8. PMID 2541784 DOI: 10.1016/0167-4781(89)90181-4  0.41
1988 Smythe C, Caudwell FB, Ferguson M, Cohen P. Isolation and structural analysis of a peptide containing the novel tyrosyl-glucose linkage in glycogenin. The Embo Journal. 7: 2681-2686. DOI: 10.1002/J.1460-2075.1988.Tb03121.X  0.323
1987 Berndt N, Campbell DG, Caudwell FB, Cohen P, da Cruz e Silva EF, da Cruz e Silva OB, Cohen PT. Isolation and sequence analysis of a cDNA clone encoding a type-1 protein phosphatase catalytic subunit: homology with protein phosphatase 2A. Febs Letters. 223: 340-6. PMID 2822491 DOI: 10.1016/0014-5793(87)80316-2  0.745
1985 Tung HY, Alemany S, Cohen P. The protein phosphatases involved in cellular regulation. 2. Purification, subunit structure and properties of protein phosphatases-2A0, 2A1, and 2A2 from rabbit skeletal muscle. European Journal of Biochemistry. 148: 253-63. PMID 2985385 DOI: 10.1111/J.1432-1033.1985.Tb08833.X  0.325
1983 Klee CB, Krinks MH, Manalan AS, Cohen P, Stewart AA. Isolation and characterization of bovine brain calcineurin: a calmodulin-stimulated protein phosphatase. Methods in Enzymology. 102: 227-44. PMID 6316077 DOI: 10.1016/S0076-6879(83)02024-8  0.505
1979 Shenolikar S, Cohen PT, Cohen P, Nairn AC, Perry SV. The role of calmodulin in the structure and regulation of phosphorylase kinase from rabbit skeletal muscle. European Journal of Biochemistry / Febs. 100: 329-37. PMID 159817 DOI: 10.1111/J.1432-1033.1979.Tb04175.X  0.368
1978 Burchell A, Foulkes JG, Cohen PTW, Condon GD, Cohen P. Evidence for the involvement of protein phosphatase-1 in the regulation of metabolic processes other than glycogen metabolism. Febs Letters. 92: 68-72. PMID 208871 DOI: 10.1016/0014-5793(78)80723-6  0.348
1978 Cohen P, Burchell A, Foulkes JG, Cohen PTW, Vanaman TC, Nairin AC. Identification of the Ca2+-dependent modulator protein as the fourth subunit of rabbit skeletal muscle phosphorylase kinase Febs Letters. 92: 287-293. DOI: 10.1016/0014-5793(78)80772-8  0.41
1976 Burchell A, Cohen PTW, Cohen P. Distribution of isoenzymes of the glycogenolytic cascade in different types of muscle fibre. Febs Letters. 67: 17-22. PMID 1066284 DOI: 10.1016/0014-5793(76)80861-7  0.389
1976 Cohen PTW, Burchell A, Cohen P. The Molecular Basis of Skeletal Muscle Phosphorylase Kinase Deficiency Febs Journal. 66: 347-356. PMID 820556 DOI: 10.1111/J.1432-1033.1976.Tb10524.X  0.31
1973 Cohen PTWW, Cohen P. Skeletal muscle phosphorylase kinase deficiency: detection of a protein lacking any activity in ICR-IAn mice. Febs Letters. 29: 113-116. PMID 4198146 DOI: 10.1016/0014-5793(73)80538-1  0.379
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