Ian A. Blair - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
biochemistry, pharmacology, chemistry, mass spectrometry, toxicology
Website:
https://www.med.upenn.edu/apps/faculty/index.php/g275/p18766

222 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Riscal R, Gardner SM, Coffey NJ, Carens M, Mesaros C, Xu JP, Xue Y, Davis L, Demczyszyn S, Vogt A, Olia A, Finan JM, Godfrey J, Schultz DC, Blair IA, et al. Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma. Cancer Research. PMID 38417134 DOI: 10.1158/0008-5472.CAN-23-0821  0.524
2021 Snyder NW, O Brien J, Singh B, Buchan G, Arroyo AD, Liu X, Bostwick A, Varner EL, Angajala A, Sobol RW, Blair IA, Mesaros C, Wendell SG. Primary saturation of α, β-unsaturated carbonyl containing fatty acids does not abolish electrophilicity. Chemico-Biological Interactions. 109689. PMID 34634267 DOI: 10.1016/j.cbi.2021.109689  0.538
2020 Li F, Huangyang P, Burrows M, Guo K, Riscal R, Godfrey J, Lee KE, Lin N, Lee P, Blair IA, Keith B, Li B, Simon MC. FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome. Nature Cell Biology. PMID 32367049 DOI: 10.1038/S41556-020-0511-2  0.305
2019 Uribe-Herranz M, Rafail S, Beghi S, Gil-de-Gómez L, Verginadis I, Bittinger K, Pustylnikov S, Pierini S, Perales-Linares R, Blair IA, Mesaros CA, Snyder NW, Bushman F, Koumenis C, Facciabene A. Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response. The Journal of Clinical Investigation. PMID 31815742 DOI: 10.1172/Jci124332  0.542
2019 Kamel AM, Bowlin S, Anwar B, Reichard H, Argus J, Blair IA. In vitro Biotransformation of the Nrf2 activator Bardoxolone: Formation of an Epoxide Metabolite that Undergoes Two Novel Glutathione-Mediated Metabolic Pathways; Epoxide Reduction and Oxidative Elimination of Nitrile Moiety. Chemical Research in Toxicology. PMID 31613099 DOI: 10.1021/Acs.Chemrestox.9B00289  0.309
2019 Wang S, Blair IA, Mesaros C. Analytical Methods for Mass Spectrometry-Based Metabolomics Studies. Advances in Experimental Medicine and Biology. 1140: 635-647. PMID 31347076 DOI: 10.1007/978-3-030-15950-4_38  0.36
2019 Lee SC, Shestov AA, Guo L, Zhang Q, Roman JC, Liu X, Wang HY, Pickup S, Nath K, Lu P, Hofbauer S, Mesaros C, Wang YL, Nelson DS, Schuster SJ, ... Blair IA, et al. Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells. Molecular Cancer Research : McR. PMID 30862686 DOI: 10.1158/1541-7786.Mcr-18-0256  0.365
2019 Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Rocha AG, Dancis A, Mesaros C, Lynch DR, Blair IA. Correction to Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia. Analytical Chemistry. PMID 30676739 DOI: 10.1021/Acs.Analchem.9B00141  0.332
2019 Lynch DR, Farmer J, Hauser L, Blair IA, Wang QQ, Mesaros C, Snyder N, Boesch S, Chin M, Delatycki MB, Giunti P, Goldsberry A, Hoyle C, McBride MG, Nachbauer W, et al. Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia. Annals of Clinical and Translational Neurology. 6: 15-26. PMID 30656180 DOI: 10.1002/Acn3.660  0.556
2019 Sela Y, Li J, Doepner M, Maheswaran S, Mesaros C, Blair I, Shalem O, Stanger B. Abstract C50: Dissecting vulnerabilities of pancreatic tumors’ silent fraction unravels secrets of an alternative cell state Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C50  0.346
2019 Campbell SL, Mesaros CA, Tsang T, Noji M, Kruijning S, Trefely S, Izzo L, Blair IA, Wellen KE. Abstract C10: Glutamine deprivation triggers hexosamine salvage in pancreatic cancer cells Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C10  0.349
2018 Murray JR, Mesaros CA, Arlt VM, Seidel A, Blair IA, Penning TM. Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone. Chemical Research in Toxicology. PMID 30406992 DOI: 10.1021/Acs.Chemrestox.8B00250  0.313
2018 O'Neill K, Alexander J, Azuma R, Xiao R, Snyder NW, Mesaros CA, Blair IA, Pinney SE. Gestational Diabetes Alters the Metabolomic Profile in 2nd Trimester Amniotic Fluid in a Sex-Specific Manner. International Journal of Molecular Sciences. 19. PMID 30201937 DOI: 10.3390/Ijms19092696  0.593
2018 Weng L, Guo L, Vachani A, Mesaros CA, Blair IA. Quantification of Serum High Mobility Group Box-1 by Liquid Chromatography High Resolution Mass Spectrometry: Implications for its role in Immunity, Inflammation, and Cancer. Analytical Chemistry. PMID 29791130 DOI: 10.1021/Acs.Analchem.8B01175  0.314
2018 Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, Li B, Wubbenhorst B, Maguire TG, Nathanson KL, Alwine JC, ... Blair IA, et al. Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity. Cell Metabolism. PMID 29754953 DOI: 10.1016/J.Cmet.2018.04.009  0.301
2018 Sinclair WR, Shrimp JH, Zengeya TT, Kulkarni RA, Garlick JM, Luecke H, Worth AJ, Blair IA, Snyder NW, Meier JL. Bioorthogonal pro-metabolites for profiling short chain fatty acylation. Chemical Science. 9: 1236-1241. PMID 29675169 DOI: 10.1039/C7Sc00247E  0.598
2018 O'Connor RS, Guo L, Ghassemi S, Snyder NW, Worth AJ, Weng L, Kam Y, Philipson B, Trefely S, Nunez-Cruz S, Blair IA, June CH, Milone MC. The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations. Scientific Reports. 8: 6289. PMID 29674640 DOI: 10.1038/S41598-018-24676-6  0.585
2018 Ecker C, Guo L, Voicu S, Gil-de-Gómez L, Medvec A, Cortina L, Pajda J, Andolina M, Torres-Castillo M, Donato JL, Mansour S, Zynda ER, Lin PY, Varela-Rohena A, Blair IA, et al. Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments. Cell Reports. 23: 741-755. PMID 29669281 DOI: 10.1016/J.Celrep.2018.03.084  0.302
2018 Wang Q, Guo L, Strawser CJ, Hauser LA, Hwang WT, Snyder NW, Lynch DR, Mesaros C, Blair IA. Low apolipoprotein A-I levels in Friedreich's ataxia and in frataxin-deficient cells: Implications for therapy. Plos One. 13: e0192779. PMID 29447225 DOI: 10.1371/Journal.Pone.0192779  0.572
2018 Mazaleuskaya LL, Salamatipour A, Sarantopoulou D, Weng L, FitzGerald GA, Blair IA, Mesaros C. Analysis of hydroxyeicosatetraenoic acids (HETEs) in human whole blood by chiral ultrahigh performance liquid chromatgraphy (UHPLC)-electron capture atmospheric pressure chemical ionization/high resolution mass spectrometry (ECAPCI/HRMS). Journal of Lipid Research. PMID 29301865 DOI: 10.1194/Jlr.D081414  0.339
2017 Shrimp JH, Garlick J, Tezil T, Sorum AW, Worth AJ, Blair IA, Verdin E, Snyder NW, Meier JL. Defining metabolic and non-metabolic regulation of histone acetylation by a NSAID chemotype. Molecular Pharmaceutics. PMID 29240439 DOI: 10.1021/Acs.Molpharmaceut.7B00943  0.593
2017 Huang M, Mesaros CA, Hackfield LC, Hodge RP, Blair IA, Penning TM. Potential Metabolic Activation of Representative Alkylated Polycyclic Aromatic Hydrocarbons 1-Methylphenanthrene and 9-Ethylphenanthrene Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells. Chemical Research in Toxicology. PMID 29035516 DOI: 10.1021/Acs.Chemrestox.7B00232  0.349
2017 Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, ... ... Blair IA, et al. Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chemical Biology. PMID 28919040 DOI: 10.1016/J.Chembiol.2017.08.009  0.309
2017 Sims C, Salliant N, Worth AJ, Parry R, Mesaros C, Blair IA, Snyder NW. Metabolic tracing analysis reveals substrate-specific metabolic deficits in platelet storage lesion. Transfusion. PMID 28836286 DOI: 10.1111/Trf.14292  0.56
2017 Else T, Marcondes Lerario A, Everett J, Haymon L, Wham D, Mullane M, Wilson TL, Rainville I, Rana H, Worth AJ, Snyder NW, Blair IA, McKay R, Kilbridge K, Hammer GD, et al. Adrenocortical carcinoma and succinate dehydrogenase gene mutations. European Journal of Endocrinology. PMID 28819017 DOI: 10.1530/Eje-17-0358  0.454
2017 Xu R, Mesaros C, Weng L, Snyder NW, Vachani A, Blair IA, Hwang WT. Comparison of statistical methods for detection of serum lipid biomarkers for mesothelioma and asbestos exposure. Biomarkers in Medicine. PMID 28534416 DOI: 10.2217/Bmm-2017-0087  0.546
2017 Angelin A, Gil-de-Gómez L, Dahiya S, Jiao J, Guo L, Levine MH, Wang Z, Quinn WJ, Kopinski PK, Wang L, Akimova T, Liu Y, Bhatti TR, Han R, Laskin BL, ... ... Blair IA, et al. Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments. Cell Metabolism. PMID 28416194 DOI: 10.1016/J.Cmet.2016.12.018  0.308
2017 Huang M, Mesaros CA, Hackfield LC, Hodge RP, Zang T, Blair IA, Penning TM. Potential Metabolic Activation of a Representative C4-Alkylated Polycyclic Aromatic Hydrocarbon Retene (1-Methyl-7-isopropyl-phenanthrene) Associated With the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells. Chemical Research in Toxicology. PMID 28278373 DOI: 10.1021/Acs.Chemrestox.6B00457  0.34
2017 Mesaros C, Arroyo AD, Blair IA, Snyder NW. Coenzyme A thioester formation of 11- and 15-oxo-eicosatetraenoic acid. Prostaglandins & Other Lipid Mediators. PMID 28238887 DOI: 10.1016/J.Prostaglandins.2017.02.004  0.624
2017 Kulkarni RA, Worth AJ, Zengeya TT, Shrimp JH, Garlick JM, Roberts AM, Montgomery DC, Sourbier C, Gibbs BK, Mesaros C, Tsai YC, Das S, Chan KC, Zhou M, Andresson T, ... ... Blair IA, et al. Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling. Cell Chemical Biology. PMID 28163016 DOI: 10.1016/J.Chembiol.2017.01.002  0.585
2017 Carrer A, Parris JL, Trefely S, Henry RA, Montgomery DC, Torres A, Viola JM, Kuo YM, Blair IA, Meier JL, Andrews AJ, Snyder NW, Wellen KE. Impact of High Fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels. The Journal of Biological Chemistry. PMID 28077572 DOI: 10.1074/Jbc.M116.750620  0.555
2016 Kawalekar OU, O' Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD, Patel PR, Guedan S, Scholler J, Keith B, Snyder NW, Blair IA, Milone MC, June CH. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells. Immunity. 44: 712. PMID 28843072 DOI: 10.1016/j.immuni.2016.02.023  0.512
2016 Pinney SE, Mesaros CA, Snyder NW, Busch CM, Xiao R, Aijaz S, Ijaz N, Blair IA, Manson JM. Second trimester amniotic fluid bisphenol a concentration is associated with decreased birth weight in term infants. Reproductive Toxicology (Elmsford, N.Y.). PMID 27829162 DOI: 10.1016/J.Reprotox.2016.11.007  0.546
2016 Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, et al. ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch. Cell Reports. 17: 1037-1052. PMID 27760311 DOI: 10.1016/J.Celrep.2016.09.069  0.61
2016 Frey AJ, Wang Q, Busch C, Feldman D, Bottalico L, Mesaros CA, Blair IA, Vachani A, Snyder NW. Validation of highly sensitive simultaneous targeted and untargeted analysis of keto-steroids by Girard P derivatization and stable isotope dilution-liquid chromatography-high resolution mass spectrometry. Steroids. PMID 27743906 DOI: 10.1016/J.Steroids.2016.10.003  0.592
2016 Mesaros C, Blair IA. Mass spectrometry-based approaches to targeted quantitative proteomics in cardiovascular disease. Clinical Proteomics. 13: 20. PMID 27713681 DOI: 10.1186/S12014-016-9121-1  0.323
2016 Nath K, Guo L, Nancolas B, Nelson DS, Shestov AA, Lee SC, Roman J, Zhou R, Leeper DB, Halestrap AP, Blair IA, Glickson JD. Mechanism of antineoplastic activity of lonidamine. Biochimica Et Biophysica Acta. PMID 27497601 DOI: 10.1016/J.Bbcan.2016.08.001  0.311
2016 Guo L, Worth AJ, Mesaros C, Snyder NW, Glickson JD, Blair IA. Diisopropylethylamine/hexafluoroisopropanol-mediated ion-pairing ultra-high-performance liquid chromatography/mass spectrometry for phosphate and carboxylate metabolite analysis: utility for studying cellular metabolism. Rapid Communications in Mass Spectrometry : Rcm. 30: 1835-45. PMID 27476658 DOI: 10.1002/Rcm.7667  0.617
2016 Shestov AA, Lee SC, Nath K, Guo L, Nelson DS, Roman JC, Leeper DB, Wasik MA, Blair IA, Glickson JD. (13)C MRS and LC-MS Flux Analysis of Tumor Intermediary Metabolism. Frontiers in Oncology. 6: 135. PMID 27379200 DOI: 10.3389/Fonc.2016.00135  0.365
2016 Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, ... ... Blair IA, et al. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. The Journal of Clinical Investigation. PMID 27294527 DOI: 10.1172/Jci85796  0.533
2016 Worth AJ, Marchione DM, Parry RC, Wang Q, Gillespie KP, Saillant NN, Sims C, Mesaros C, Snyder NW, Blair IA. LC-MS Analysis of Human Platelets as a Platform for Studying Mitochondrial Metabolism. Journal of Visualized Experiments : Jove. PMID 27077278 DOI: 10.3791/53941  0.614
2016 Huang M, Mesaros CA, Zhang S, Blair IA, Penning TM. Potential Metabolic Activation of a Representative C2-Alkylated Polycyclic Aromatic Hydrocarbon (PAH) 6-Ethylchrysene Associated With the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells. Chemical Research in Toxicology. PMID 27054409 DOI: 10.1021/Acs.Chemrestox.6B00036  0.343
2016 Daurio NA, Tuttle SW, Worth AJ, Song EY, Davis JM, Snyder NW, Blair IA, Koumenis C. AMPK activation and metabolic reprogramming by tamoxifen through estrogen receptor-independent mechanisms suggests new uses for this therapeutic modality in cancer treatment. Cancer Research. PMID 27020861 DOI: 10.1158/0008-5472.Can-15-2197  0.589
2016 Covarrubias AJ, Aksoylar HI, Yu J, Snyder NW, Worth AJ, Iyer SS, Wang J, Ben-Sahra I, Byles V, Polynne-Stapornkul T, Espinosa EC, Lamming D, Manning BD, Zhang Y, Blair IA, et al. Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation. Elife. 5. PMID 26894960 DOI: 10.7554/Elife.11612  0.571
2016 Kawalekar OU, O'Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD, Patel PR, Guedan S, Scholler J, Keith B, Snyder N, Blair I, Milone MC, June CH. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells. Immunity. 44: 380-390. PMID 26885860 DOI: 10.1016/J.Immuni.2016.01.021  0.56
2016 Bedi KC, Snyder NW, Brandimarto J, Aziz M, Mesaros C, Worth A, Wang L, Javaheri A, Blair IA, Margulies K, Rame JE. Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure. Circulation. PMID 26819374 DOI: 10.1161/Circulationaha.115.017545  0.557
2016 Wang Q, Mesaros C, Blair IA. Ultra-high sensitivity analysis of estrogens for special populations in serum and plasma by liquid chromatography-mass spectrometry: Assay considerations and suggested practices. The Journal of Steroid Biochemistry and Molecular Biology. PMID 26767303 DOI: 10.1016/J.Jsbmb.2016.01.002  0.346
2016 Shestov AA, Guo L, Lee S, Nelson DS, Blair IA, Wasik MA, Glickson JD. Abstract A14: 13C metabolomic and fluxomic study of human B-cell lymphoma metabolic network: Quantifying glutaminolysis and reductive carboxylation Cancer Research. 76. DOI: 10.1158/1538-7445.Fbcr15-A14  0.395
2016 Carrer A, Lee JV, Shah S, Aiello NM, Snyder NW, Worth AJ, Blair IA, Stanger BZ, Wellen KE. Abstract PR03: Exploring the link between Kras and histone acetylation Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-Pr03  0.588
2016 Guo Z, Sevrioukova I, Hanse E, Zhang X, Denisov I, Chiu T, Cuellar R, Torres C, Wulfkuhle J, Petricoin E, Cao Q, Chu H, Norris B, Schumacher R, Kelekar A, ... Blair I, et al. Abstract 44: Hexyl-benzyl-biguanide (HBB) potently and selectively inhibits CYP3A4 epoxygenase activity and inhibits EET stabilization of mitochondrial respiration in ER+HER2- breast cancer cells, inducing glycolysis and pyruvate biosynthesis Cancer Research. 76: 44-44. DOI: 10.1158/1538-7445.Am2016-44  0.313
2016 Kawalekar OU, O' Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD, Patel PR, Guedan S, Scholler J, Keith B, Snyder NW, Blair IA, Milone MC, June CH. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells [Immunity 44, 380-390, (2016)] Immunity. 44: 712. DOI: 10.1016/j.immuni.2016.02.023  0.508
2015 Shestov AA, Mancuso A, Lee SC, Guo L, Nelson DS, Roman JC, Henry PG, Leeper DB, Blair IA, Glickson JD. Bonded Cumomer Analysis of Human Melanoma Metabolism Monitored by 13C NMR Spectroscopy of Perfused Tumor Cells. The Journal of Biological Chemistry. PMID 26703469 DOI: 10.1074/Jbc.M115.701862  0.339
2015 Guo L, Shestov AA, Worth AJ, Nath K, Nelson DS, Leeper DB, Glickson JD, Blair IA. Inhibition of mitochondrial complex II by the anti-cancer agent lonidamine. The Journal of Biological Chemistry. PMID 26521302 DOI: 10.1074/Jbc.M115.697516  0.342
2015 Huang M, Zhang L, Mesaros CA, Hackfield L, Hodge RP, Blair IA, Penning TM. Metabolism of an Alkylated Polycyclic Aromatic Hydrocarbon (PAH) 5-Methylchrysene in Human Hepatoma (HepG2) Cells. Chemical Research in Toxicology. PMID 26395544 DOI: 10.1021/Acs.Chemrestox.5B00256  0.313
2015 Wang Q, Zhang S, Guo L, Busch CM, Jian W, Weng N, Snyder NW, Rangiah K, Mesaros C, Blair IA. Serum apolipoprotein A-1 quantification by LC-MS with a SILAC internal standard reveals reduced levels in smokers. Bioanalysis. PMID 26394123 DOI: 10.4155/Bio.15.195  0.681
2015 Snyder NW, Mesaros C, Blair IA. Translational metabolomics in cancer research. Biomarkers in Medicine. 9: 821-34. PMID 26329905 DOI: 10.2217/Bmm.15.52  0.55
2015 Worth AJ, Basu SS, Deutsch EC, Hwang WT, Snyder NW, Lynch DR, Blair IA. Stable isotopes and LC-MS for monitoring metabolic disturbances in Friedreich's ataxia platelets. Bioanalysis. 7: 1843-55. PMID 26295986 DOI: 10.4155/Bio.15.118  0.735
2015 Mesaros C, Worth AJ, Snyder NW, Christofidou-Solomidou M, Vachani A, Albelda SM, Blair IA. Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure. Bioanalysis. 7: 1157-73. PMID 26039812 DOI: 10.4155/Bio.15.53  0.543
2015 Cossette C, Gravel S, Reddy CN, Gore V, Chourey S, Ye Q, Snyder NW, Mesaros CA, Blair IA, Lavoie JP, Reinero CR, Rokach J, Powell WS. Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes. Biochemical Pharmacology. 96: 247-55. PMID 26032638 DOI: 10.1016/J.Bcp.2015.05.009  0.547
2015 Aird KM, Worth AJ, Snyder NW, Lee JV, Sivanand S, Liu Q, Blair IA, Wellen KE, Zhang R. ATM couples replication stress and metabolic reprogramming during cellular senescence. Cell Reports. 11: 893-901. PMID 25937285 DOI: 10.1016/J.Celrep.2015.04.014  0.57
2015 Worth AJ, Gillespie KP, Mesaros C, Guo L, Basu SS, Snyder NW, Blair IA. Rotenone Stereospecifically Increases (S)-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells. Chemical Research in Toxicology. 28: 948-54. PMID 25800467 DOI: 10.1021/Tx500535C  0.739
2015 Wang Q, Rangiah K, Mesaros C, Snyder NW, Vachani A, Song H, Blair IA. Ultrasensitive quantification of serum estrogens in postmenopausal women and older men by liquid chromatography-tandem mass spectrometry. Steroids. 96: 140-52. PMID 25637677 DOI: 10.1016/J.Steroids.2015.01.014  0.589
2015 Snyder NW, Tombline G, Worth AJ, Parry RC, Silvers JA, Gillespie KP, Basu SS, Millen J, Goldfarb DS, Blair IA. Production of stable isotope-labeled acyl-coenzyme A thioesters by yeast stable isotope labeling by essential nutrients in cell culture. Analytical Biochemistry. 474: 59-65. PMID 25572876 DOI: 10.1016/J.Ab.2014.12.014  0.748
2015 Snyder NW, Golin-Bisello F, Gao Y, Blair IA, Freeman BA, Wendell SG. 15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways. Chemico-Biological Interactions. 234: 144-53. PMID 25450232 DOI: 10.1016/J.Cbi.2014.10.029  0.592
2015 Snyder NW, Basu SS, Worth AJ, Mesaros C, Blair IA. Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets. Journal of Lipid Research. 56: 142-50. PMID 25424005 DOI: 10.1194/Jlr.M055384  0.755
2015 Wang Q, Bottalico L, Mesaros C, Blair IA. Analysis of estrogens and androgens in postmenopausal serum and plasma by liquid chromatography-mass spectrometry. Steroids. 99: 76-83. PMID 25150018 DOI: 10.1016/J.Steroids.2014.08.012  0.331
2015 Covarrubias AJ, Aksoylar HI, Yu J, Snyder NW, Worth AJ, Iyer SS, Wang J, Ben-Sahra I, Byles V, Polynne-Stapornkul T, Espinosa EC, Lamming D, Manning BD, Zhang Y, Blair IA, et al. Author response: Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation Elife. DOI: 10.7554/Elife.11612.024  0.551
2015 Mesaros C, Worth AJ, Snyder NW, Christofidou-Solomidou M, Vachani A, Albelda SM, Blair IA. Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure Bioanalysis. 7: 1157-1173. DOI: 10.4155/bio.15.53  0.48
2015 Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Burrill JS, Guo L, Sacristan C, Furlan SN, ... ... Blair IA, et al. Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality Blood. 126: 147-147. DOI: 10.1182/Blood.V126.23.147.147  0.535
2015 Carrer A, Lee JV, Shah S, Snyder NW, Jackson E, Aiello NM, Garcia BA, Chodosh LA, Stanger BZ, Blair IA, Wellen KE. Abstract B40: Oncogenic Kras induces histone acetylation in pancreatic ductal adenocarcinoma Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B40  0.586
2015 Rame J, Bedi K, Snyder N, Brandimarto J, Mesaros C, Birati E, Blair I, Margulies K. Myocardial Lipid Metabolism in the End-Stage Failing: Heart: Evidence for an Energy-Starved State The Journal of Heart and Lung Transplantation. 34: S89-S90. DOI: 10.1016/J.Healun.2015.01.239  0.538
2015 Aird KM, Worth AJ, Snyder NW, Lee JV, Sivanand S, Liu Q, Blair IA, Wellen KE, Zhang R. ATM Couples Replication Stress and Metabolic Reprogramming during Cellular Senescence Cell Reports. 11: 893-901. DOI: 10.1016/j.celrep.2015.04.014  0.5
2014 Snyder NW, Basu SS, Zhou Z, Worth AJ, Blair IA. Stable isotope dilution liquid chromatography/mass spectrometry analysis of cellular and tissue medium- and long-chain acyl-coenzyme A thioesters. Rapid Communications in Mass Spectrometry : Rcm. 28: 1840-8. PMID 25559454 DOI: 10.1002/Rcm.6958  0.734
2014 Worth AJ, Basu SS, Snyder NW, Mesaros C, Blair IA. Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid β-oxidation, supporting acetyl-coenzyme A levels. The Journal of Biological Chemistry. 289: 26895-903. PMID 25122772 DOI: 10.1074/Jbc.M114.591354  0.742
2014 Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, ... ... Blair IA, et al. Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metabolism. 20: 306-19. PMID 24998913 DOI: 10.1016/J.Cmet.2014.06.004  0.573
2014 Summers CM, Hammons AL, Arora J, Zhang S, Jochems J, Blair IA, Whitehead AS. Methotrexate modulates folate phenotype and inflammatory profile in EA.hy 926 cells. European Journal of Pharmacology. 732: 60-7. PMID 24657277 DOI: 10.1016/J.Ejphar.2014.03.004  0.78
2014 Huang M, Zhang L, Mesaros C, Zhang S, Blaha MA, Blair IA, Penning TM. Metabolism of a representative oxygenated polycyclic aromatic hydrocarbon (PAH) phenanthrene-9,10-quinone in human hepatoma (HepG2) cells Chemical Research in Toxicology. 27: 852-863. PMID 24646012 DOI: 10.1021/Tx500031P  0.346
2014 Darpolor MM, Basu SS, Worth A, Nelson DS, Clarke-Katzenberg RH, Glickson JD, Kaplan DE, Blair IA. The aspartate metabolism pathway is differentiable in human hepatocellular carcinoma: transcriptomics and (13) C-isotope based metabolomics. Nmr in Biomedicine. 27: 381-9. PMID 24497316 DOI: 10.1002/Nbm.3072  0.661
2013 Basu SS, Deutsch EC, Schmaier AA, Lynch DR, Blair IA. Human platelets as a platform to monitor metabolic biomarkers using stable isotopes and LC-MS. Bioanalysis. 5: 3009-21. PMID 24320127 DOI: 10.4155/Bio.13.269  0.667
2013 Blair IA. Stable isotope dilution gas chromatography/mass spectrometry of prostaglandins and leukotrienes. Biological Trace Element Research. 12: 259-60. PMID 24254608 DOI: 10.1007/Bf02796685  0.345
2013 Snyder NW, Revello SD, Liu X, Zhang S, Blair IA. Cellular uptake and antiproliferative effects of 11-oxo-eicosatetraenoic acid. Journal of Lipid Research. 54: 3070-7. PMID 23945567 DOI: 10.1194/Jlr.M040741  0.585
2013 Tamae D, Byrns M, Marck B, Mostaghel EA, Nelson PS, Lange P, Lin D, Taplin ME, Balk S, Ellis W, True L, Vessella R, Montgomery B, Blair IA, Penning TM. Development, validation and application of a stable isotope dilution liquid chromatography electrospray ionization/selected reaction monitoring/mass spectrometry (SID-LC/ESI/SRM/MS) method for quantification of keto-androgens in human serum. The Journal of Steroid Biochemistry and Molecular Biology. 138: 281-9. PMID 23851165 DOI: 10.1016/J.Jsbmb.2013.06.014  0.324
2013 Snyder NW, Khezam M, Mesaros CA, Worth A, Blair IA. Untargeted metabolomics from biological sources using ultraperformance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS). Journal of Visualized Experiments : Jove. e50433. PMID 23711563 DOI: 10.3791/50433  0.59
2013 VerMilyea M, Mesaros C, Snyder N, Blair I, Coutifaris C. Is there an increase in non-voc leachates from disposable sterile IVF culture plasticware over time? Fertility and Sterility. 100: S252. DOI: 10.1016/J.Fertnstert.2013.07.1190  0.511
2012 Mesaros C, Blair IA. Targeted chiral analysis of bioactive arachidonic Acid metabolites using liquid-chromatography-mass spectrometry. Metabolites. 2: 337-65. PMID 24957514 DOI: 10.3390/Metabo2020337  0.371
2012 Wu A, Xu D, Lu D, Penning TM, Blair IA, Harvey RG. Synthesis of (13) C 4-labelled oxidized metabolites of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene. Tetrahedron. 68. PMID 24244053 DOI: 10.1016/J.Tet.2012.05.130  0.324
2012 Hammons AL, Summers CM, Jochems J, Arora JS, Zhang S, Blair IA, Whitehead AS. Pemetrexed alters folate phenotype and inflammatory profile in EA.hy 926 cells grown under low-folate conditions. European Journal of Pharmacology. 696: 12-7. PMID 22975265 DOI: 10.1016/J.Ejphar.2012.08.008  0.788
2012 MacDonald ML, Ciccimaro E, Prakash A, Banerjee A, Seeholzer SH, Blair IA, Hahn CG. Biochemical fractionation and stable isotope dilution liquid chromatography-mass spectrometry for targeted and microdomain-specific protein quantification in human postmortem brain tissue Molecular and Cellular Proteomics. 11: 1670-1681. PMID 22942359 DOI: 10.1074/Mcp.M112.021766  0.726
2012 Zhang L, Huang M, Blair IA, Penning TM. Detoxication of benzo[a]pyrene-7,8-dione by sulfotransferases (SULTS) in human lung cells Journal of Biological Chemistry. 287: 29909-29920. PMID 22782890 DOI: 10.1074/Jbc.M112.386052  0.312
2012 Mesaros C, Arora JS, Wholer A, Vachani A, Blair IA. 8-Oxo-2′-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress Free Radical Biology and Medicine. 53: 610-617. PMID 22613262 DOI: 10.1016/J.Freeradbiomed.2012.04.006  0.352
2012 Ciccimaro E, Blair IA. Bioanalysis young investigator: Eugene ciccimaro Bioanalysis. 4: 875-877. PMID 22533562 DOI: 10.4155/Bio.12.63  0.728
2012 Huang M, Liu X, Basu SS, Zhang L, Kushman ME, Harvey RG, Blair IA, Penning TM. Metabolism and distribution of benzo[a]pyrene-7,8-dione (B[a]P-7,8-dione) in human lung cells by liquid chromatography tandem mass spectrometry: Detection of an adenine B[a]P-7,8-dione adduct Chemical Research in Toxicology. 25: 993-1003. PMID 22480306 DOI: 10.1021/Tx200463S  0.655
2012 Wehr AY, Hwang WT, Blair IA, Yu KH. Relative quantification of serum proteins from pancreatic ductal adenocarcinoma patients by stable isotope dilution liquid chromatography-mass spectrometry Journal of Proteome Research. 11: 1749-1758. PMID 22264027 DOI: 10.1021/Pr201011F  0.781
2012 Basu SS, Blair IA. SILEC: A protocol for generating and using isotopically labeled coenzyme A mass spectrometry standards Nature Protocols. 7: 1-11. PMID 22157971 DOI: 10.1038/Nprot.2011.421  0.653
2012 Gelhaus SL, Gilad O, Hwang WT, Penning TM, Blair IA. Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells Toxicology Letters. 209: 58-66. PMID 22155354 DOI: 10.1016/J.Toxlet.2011.11.021  0.307
2012 Snyder NW, Revello SD, Liu X, Zhang S, Arora JS, Blair IA. Abstract LB-9: Cyclooxygenase-2/15-prostaglandin dehydrogenase derived endogenous canonical NF-κB inhibitors Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-9  0.59
2012 Revello SD, Snyder NW, Liu X, Zhang S, Arora JS, Blair IA. Abstract LB-10: Distribution and potency of anti-proliferative arachidonic acid metabolites Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-10  0.612
2011 Arora JS, Oe T, Blair IA. Synthesis of deuterium-labeled analogs of the lipid hydroperoxide-derived bifunctional electrophile 4-oxo-2(E)-nonenal. Journal of Labelled Compounds & Radiopharmaceuticals. 54: 247-251. PMID 25152561 DOI: 10.1002/Jlcr.1860  0.357
2011 Gelhaus SL, Mesaros AC, Blair IA. Cellular lipid extraction for targeted stable isotope dilution liquid chromatography-mass spectrometry analysis. Journal of Visualized Experiments : Jove. PMID 22127066 DOI: 10.3791/3399  0.395
2011 Speed N, Blair IA. Cyclooxygenase- and lipoxygenase-mediated DNA damage Cancer and Metastasis Reviews. 30: 437-447. PMID 22009064 DOI: 10.1007/S10555-011-9298-8  0.305
2011 Lu D, Harvey RG, Blair IA, Penning TM. Quantitation of benzo[a]pyrene metabolic profiles in human bronchoalveolar (H358) cells by stable isotope dilution liquid chromatography-atmospheric pressure chemical ionization mass spectrometry Chemical Research in Toxicology. 24: 1905-1914. PMID 21962213 DOI: 10.1021/Tx2002614  0.348
2011 Basu SS, Blair IA. Rotenone-mediated changes in intracellular coenzyme A thioester levels: Implications for mitochondrial dysfunction Chemical Research in Toxicology. 24: 1630-1632. PMID 21950265 DOI: 10.1021/Tx200366J  0.66
2011 Liu X, Zhang S, Arora JS, Snyder NW, Shah SJ, Blair IA. 11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid. Chemical Research in Toxicology. 24: 2227-36. PMID 21916491 DOI: 10.1021/Tx200336F  0.614
2011 DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, Mangal D, Yu KH, Yeo CJ, Calhoun ES, Scrimieri F, Winter JM, Hruban RH, Iacobuzio-Donahue C, Kern SE, ... Blair IA, et al. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature. 475: 106-9. PMID 21734707 DOI: 10.1038/Nature10189  0.489
2011 Wehr AY, Furth EE, Sangar V, Blair IA, Yu KH. Analysis of the human pancreatic stellate cell secreted proteome Pancreas. 40: 557-566. PMID 21499210 DOI: 10.1097/Mpa.0B013E318214Efaf  0.754
2011 Rangiah K, Shah SJ, Vachani A, Ciccimaro E, Blair IA. Liquid chromatography/mass spectrometry of pre-ionized Girard P derivatives for quantifying estrone and its metabolites in serum from postmenopausal women Rapid Communications in Mass Spectrometry. 25: 1297-1307. PMID 21488127 DOI: 10.1002/Rcm.4982  0.731
2011 Mitra R, Guo Z, Milani M, Mesaros C, Rodriguez M, Nguyen J, Luo X, Clarke D, Lamba J, Schuetz E, Donner DB, Puli N, Falck JR, Capdevila J, Gupta K, ... Blair IA, et al. CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET). The Journal of Biological Chemistry. 286: 17543-59. PMID 21402692 DOI: 10.1074/Jbc.M110.198515  0.303
2011 Basu SS, Mesaros C, Gelhaus SL, Blair IA. Stable isotope labeling by essential nutrients in cell culture for preparation of labeled coenzyme a and its thioesters Analytical Chemistry. 83: 1363-1369. PMID 21268609 DOI: 10.1021/Ac1027353  0.681
2011 Bhat SH, Gelhaus SL, Mesaros C, Vachani A, Blair IA. A new liquid chromatography/mass spectrometry method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine Rapid Communications in Mass Spectrometry. 25: 115-121. PMID 21154658 DOI: 10.1002/Rcm.4824  0.371
2011 Wehr AY, Blair IA, Yu KH. Tumor microenvironment derived biomarkers for the early detection of pancreatic cancer (PDAC). Journal of Clinical Oncology. 29: e14591-e14591. DOI: 10.1200/JCO.2011.29.15_SUPPL.E14591  0.729
2010 Mesaros C, Lee SH, Blair IA. Analysis of epoxyeicosatrienoic acids by chiral liquid chromatography/ electron capture atmospheric pressure chemical ionization mass spectrometry using [13C]-analog internal standards Rapid Communications in Mass Spectrometry. 24: 3237-3247. PMID 20972997 DOI: 10.1002/Rcm.4760  0.382
2010 Kinder M, Thompson JE, Wei C, Shelat SG, Blair IA, Carroll M, Puré E. Interferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling. Experimental Hematology. 38: 1036-1046.e1-4. PMID 20647030 DOI: 10.1016/J.Exphem.2010.07.004  0.503
2010 Kinder M, Wei C, Shelat SG, Kundu M, Zhao L, Blair IA, Puré E. Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism Blood. 115: 5012-5022. PMID 20357242 DOI: 10.1182/Blood-2009-09-243139  0.525
2010 Ciccimaro E, Blair IA. Stable-isotope dilution LC-MS for quantitative biomarker analysis Bioanalysis. 2: 311-341. PMID 20352077 DOI: 10.4155/Bio.09.185  0.736
2010 Mesaros C, Gugiu BG, Zhou R, Lee SH, Choi J, Laird J, Blair IA, Salomon RG. A 13-Oxo-9,10-epoxytridecenoate phospholipid analogue of the genotoxic 4,5-epoxy-2E-decenal: detection in vivo, chemical synthesis, and adduction with DNA. Chemical Research in Toxicology. 23: 516-27. PMID 20131875 DOI: 10.1021/Tx9002484  0.301
2010 Blair IA. Analysis of estrogens in serum and plasma from postmenopausal women: Past present, and future Steroids. 75: 297-306. PMID 20109478 DOI: 10.1016/J.Steroids.2010.01.012  0.325
2010 Penning TM, Lee SH, Jin Y, Gutierrez A, Blair IA. Liquid chromatography-mass spectrometry (LC-MS) of steroid hormone metabolites and its applications Journal of Steroid Biochemistry and Molecular Biology. 121: 546-555. PMID 20083198 DOI: 10.1016/J.Jsbmb.2010.01.005  0.336
2010 Byrns MC, Duan L, Lee SH, Blair IA, Penning TM. Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer Journal of Steroid Biochemistry and Molecular Biology. 118: 177-187. PMID 20036328 DOI: 10.1016/J.Jsbmb.2009.12.009  0.314
2010 Blair IA. Analysis of endogenous glutathione-adducts and their metabolites Biomedical Chromatography. 24: 29-38. PMID 20017120 DOI: 10.1002/Bmc.1374  0.344
2009 Middleton MK, Zukas AM, Rubinstein T, Kinder M, Wilson EH, Zhu P, Blair IA, Hunter CA, Puré E. 12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis. Infection and Immunity. 77: 5690-700. PMID 19822654 DOI: 10.1128/Iai.00560-09  0.541
2009 Rangiah K, Tippornwong M, Sangar V, Austin D, Tétreault MP, Rustgi AK, Blair IA, Yu KH. Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer. Journal of Proteome Research. 8: 5153-64. PMID 19769411 DOI: 10.1021/Pr900518V  0.365
2009 Lee SH, Blair IA. Targeted chiral lipidomics analysis of bioactive eicosanoid lipids in cellular systems Bmb Reports. 42: 401-410. PMID 19643036 DOI: 10.5483/Bmbrep.2009.42.7.401  0.36
2009 Zhu P, Jian W, Blair IA. A 4-oxo-2(E)-nonenal-derived glutathione adduct from 15-lipoxygenase-1-mediated oxidation of cytosolic and esterified arachidonic acid Free Radical Biology and Medicine. 47: 953-961. PMID 19576981 DOI: 10.1016/J.Freeradbiomed.2009.06.035  0.685
2009 Wei C, Zhu P, Shah SJ, Blair IA. 15-oxo-eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation Molecular Pharmacology. 76: 516-525. PMID 19535459 DOI: 10.1124/Mol.109.057489  0.681
2009 Weibel GL, Joshi MR, Wei C, Bates SR, Blair IA, Rothblat GH. 15(S)-lipoxygenase-1 associates with neutral lipid droplets in macrophage foam cells: Evidence of lipid droplet metabolism Journal of Lipid Research. 50: 2371-2376. PMID 19528634 DOI: 10.1194/Jlr.M900081-Jlr200  0.526
2009 Mitchell LE, Morales M, Khartulyari S, Huang Y, Murphy K, Mei M, Von Feldt JM, Blair IA, Whitehead AS. Folate and homocysteine phenotypes: Comparative findings using research and clinical laboratory data. Clinical Biochemistry. 42: 1275-81. PMID 19427846 DOI: 10.1016/J.Clinbiochem.2009.04.014  0.353
2009 Jian W, Lee SH, Williams MV, Blair IA. 5-lipoxygenase-mediated endogenous DNA damage Journal of Biological Chemistry. 284: 16799-16807. PMID 19390118 DOI: 10.1074/Jbc.M109.011841  0.569
2009 Hahn CG, Banerjee A, Macdonald ML, Cho DS, Kamins J, Nie Z, Borgmann-Winter KE, Grosser T, Pizarro A, Ciccimaro E, Arnold SE, Wang HY, Blair IA. The post-synaptic density of human postmortem brain tissues: an experimental study paradigm for neuropsychiatric illnesses. Plos One. 4: e5251. PMID 19370153 DOI: 10.1371/Journal.Pone.0005251  0.723
2009 Ciccimaro E, Hanks SK, Yu KH, Blair IA. Absolute quantification of phosphorylation on the kinase activation loop of cellular focal adhesion kinase by stable isotope dilution liquid chromatography/mass spectrometry Analytical Chemistry. 81: 3304-3313. PMID 19354260 DOI: 10.1021/Ac900204F  0.741
2009 Mesaros C, Lee SH, Blair IA. Targeted quantitative analysis of eicosanoid lipids in biological samples using liquid chromatography-tandem mass spectrometry Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 877: 2736-2745. PMID 19345647 DOI: 10.1016/J.Jchromb.2009.03.011  0.363
2009 Weibel GL, Joshi MR, Alexander ET, Zhu P, Blair IA, Rothblat GH. Overexpression of human 15(S)-lipoxygenase-1 in RAW macrophages leads to increased cholesterol mobilization and reverse cholesterol transport. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 837-42. PMID 19325142 DOI: 10.1161/Atvbaha.109.186163  0.545
2009 Mangal D, Vudathala D, Park JH, Seon HL, Penning TM, Blair IA. Analysis of 7,8-dihydro-8-oxo-2′-deoxyguanosine in cellular DNA during oxidative stress Chemical Research in Toxicology. 22: 788-797. PMID 19309085 DOI: 10.1021/Tx800343C  0.346
2009 Shah SJ, Yu KH, Sangar V, Parry SI, Blair IA. Identification and quantification of preterm birth biomarkers in human cervicovaginal fluid by liquid chromatography/tandem mass spectrometry. Journal of Proteome Research. 8: 2407-17. PMID 19271751 DOI: 10.1021/Pr8010342  0.361
2009 Yu KH, Barry CG, Austin D, Busch CM, Sangar V, Rustgi AK, Blair IA. Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery. Journal of Proteome Research. 8: 1565-76. PMID 19199705 DOI: 10.1021/Pr800904Z  0.362
2009 Lu ZY, Jensen LE, Huang Y, Kealey C, Blair IA, Whitehead AS. The up-regulation of monocyte chemoattractant protein-1 (MCP-1) in Ea.hy 926 endothelial cells under long-term low folate stress is mediated by the p38 MAPK pathway. Atherosclerosis. 205: 48-54. PMID 19152916 DOI: 10.1016/J.Atherosclerosis.2008.12.008  0.556
2009 Xu D, Penning TM, Blair IA, Harvey RG. Synthesis of phenol and quinone metabolites of benzo[a]pyrene, a carcinogenic component of tobacco smoke implicated in lung cancer. The Journal of Organic Chemistry. 74: 597-604. PMID 19132942 DOI: 10.1021/Jo801864M  0.314
2009 Ciccimaro E, Hanks SK, Blair IA. Quantification of focal adhesion kinase activation loop phosphorylation as a biomarker of Src activity. Molecular Pharmacology. 75: 658-66. PMID 19098120 DOI: 10.1124/Mol.108.052464  0.729
2009 Ciccimaro E, Hanks SK, Blair IA. Quantification of focal adhesion kinase activation loop phosphorylation as a biomarker of Src activity Molecular Pharmacology. 75: 658-666. DOI: 10.1124/mol.108.052464  0.686
2008 Lu ZY, Morales M, Khartulyari S, Mei M, Murphy KM, Stanislawska-Sachadyn A, Summers CM, Huang Y, Von Feldt JM, Blair IA, Mitchell LE, Whitehead AS. Genetic and biochemical determinants of serum concentrations of monocyte chemoattractant protein-1, a potential neural tube defect risk factor. Birth Defects Research. Part a, Clinical and Molecular Teratology. 82: 736-41. PMID 18937353 DOI: 10.1002/Bdra.20507  0.515
2008 Huang Y, Khartulyari S, Morales ME, Stanislawska-Sachadyn A, Von Feldt JM, Whitehead AS, Blair IA. Quantification of key red blood cell folates from subjects with denned MTHFR 677C>T genotypes using stable isotope dilution liquid chromatography/mass spectrometry Rapid Communications in Mass Spectrometry. 22: 2403-2412. PMID 18634122 DOI: 10.1002/Rcm.3624  0.339
2008 Park JH, Mangal D, Tacka KA, Quinn AM, Harvey RG, Blair IA, Penning TM. Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 6846-51. PMID 18474869 DOI: 10.1073/Pnas.0802776105  0.341
2008 Xu D, Duan Y, Blair IA, Penning TM, Harvey RG. Synthesis of dibenzo[def,p]chrysene, its active metabolites, and their 13C-labeled analogues. Organic Letters. 10: 1059-62. PMID 18284245 DOI: 10.1021/Ol7029323  0.35
2008 Zhu P, Oe T, Blair IA. Determination of cellular redox status by stable isotope dilution liquid chromatography/mass spectrometry analysis of glutathione and glutathione disulfide Rapid Communications in Mass Spectrometry. 22: 432-440. PMID 18215009 DOI: 10.1002/Rcm.3380  0.623
2008 Lucitt MB, Price TS, Pizarro A, Wu W, Yocum AK, Seiler C, Pack MA, Blair IA, Fitzgerald GA, Grosser T. Analysis of the zebrafish proteome during embryonic development. Molecular & Cellular Proteomics : McP. 7: 981-94. PMID 18212345 DOI: 10.1074/Mcp.M700382-Mcp200  0.66
2008 Ran C, Dai Q, Ruan Q, Penning TM, Blair IA, Harvey RG. Strategies for synthesis of adducts of omicron-quinone metabolites of carcinogenic polycyclic aromatic hydrocarbons with 2'-deoxyribonucleosides. The Journal of Organic Chemistry. 73: 992-1003. PMID 18181642 DOI: 10.1021/Jo701667U  0.309
2007 Lee SH, Blair IA. Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS) Methods in Enzymology. 433: 159-174. PMID 17954234 DOI: 10.1016/S0076-6879(07)33009-7  0.31
2007 Lee SH, Rangiah K, Williams MV, Wehr AY, DuBois RN, Blair IA. Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cells. Chemical Research in Toxicology. 20: 1665-75. PMID 17910482 DOI: 10.1021/Tx700130P  0.779
2007 Jian W, Lee SH, Mesaros C, Oe T, Elipe MV, Blair IA. A novel 4-oxo-2(E)-nonenal-derived endogenous thiadiazabicyclo glutathione adduct formed during cellular oxidative stress. Chemical Research in Toxicology. 20: 1008-18. PMID 17550273 DOI: 10.1021/Tx700001T  0.563
2007 Pettinella C, Lee SH, Cipollone F, Blair IA. Targeted quantitative analysis of fatty acids in atherosclerotic plaques by high sensitivity liquid chromatography/tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 850: 168-76. PMID 17174160 DOI: 10.1016/J.Jchromb.2006.11.023  0.35
2007 Price TS, Lucitt MB, Wu W, Austin DJ, Pizarro A, Yocum AK, Blair IA, FitzGerald GA, Grosser T. EBP, a program for protein identification using multiple tandem mass spectrometry datasets. Molecular & Cellular Proteomics : McP. 6: 527-36. PMID 17164401 DOI: 10.1074/Mcp.T600049-Mcp200  0.659
2007 Huang Y, Lu ZY, Brown KS, Whitehead AS, Blair IA. Quantification of intracellular homocysteine by stable isotope dilution liquid chromatography/tandem mass spectrometry. Biomedical Chromatography : Bmc. 21: 107-12. PMID 17121413 DOI: 10.1002/Bmc.735  0.589
2006 Lee SH, Pettinella C, Blair IA. LC/ESI/MS analysis of saturated and unsaturated fatty acids in rat intestinal epithelial cells. Current Drug Metabolism. 7: 929-37. PMID 17168692 DOI: 10.2174/138920006779010584  0.361
2006 Zheng N, Pang S, Oe T, Felix CA, Wehrli S, Blair IA. Characterization of an etoposide-glutathione conjugate derived from metabolic activation by human cytochrome p450. Current Drug Metabolism. 7: 897-911. PMID 17168690 DOI: 10.2174/138920006779010638  0.336
2006 Blair IA. Endogenous glutathione adducts. Current Drug Metabolism. 7: 853-72. PMID 17168687 DOI: 10.2174/138920006779010601  0.34
2006 Oe T, Ackermann BL, Inoue K, Berna MJ, Garner CO, Gelfanova V, Dean RA, Siemers ER, Holtzman DM, Farlow MR, Blair IA. Quantitative analysis of amyloid beta peptides in cerebrospinal fluid of Alzheimer's disease patients by immunoaffinity purification and stable isotope dilution liquid chromatography/negative electrospray ionization tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 20: 3723-35. PMID 17117458 DOI: 10.1002/Rcm.2787  0.305
2006 Ciccimaro E, Hevko J, Blair IA. Analysis of phosphorylation sites on focal adhesion kinase using nanospray liquid chromatography/multiple reaction monitoring mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 20: 3681-92. PMID 17117420 DOI: 10.1002/Rcm.2783  0.714
2006 Middleton MK, Zukas AM, Rubinstein T, Jacob M, Zhu P, Zhao L, Blair I, Puré E. Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease. The Journal of Experimental Medicine. 203: 2529-40. PMID 17043146 DOI: 10.1084/Jem.20061444  0.571
2006 Yocum AK, Busch CM, Felix CA, Blair IA. Proteomics-based strategy to identify biomarkers and pharmacological targets in leukemias with t(4;11) translocations. Journal of Proteome Research. 5: 2743-53. PMID 17022645 DOI: 10.1021/Pr060235V  0.682
2006 Pollack M, Yang IY, Kim HY, Blair IA, Moriya M. Translesion DNA Synthesis across the heptanone--etheno-2'-deoxycytidine adduct in cells. Chemical Research in Toxicology. 19: 1074-9. PMID 16918247 DOI: 10.1021/Tx0600503  0.538
2006 Zhu P, Lee SH, Wehrli S, Blair IA. Characterization of a lipid hydroperoxide-derived RNA adduct in rat intestinal epithelial cells. Chemical Research in Toxicology. 19: 809-17. PMID 16780360 DOI: 10.1021/Tx0600189  0.587
2006 Ruan Q, Kim HY, Jiang H, Penning TM, Harvey RG, Blair IA. Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 20: 1369-80. PMID 16557497 DOI: 10.1002/Rcm.2457  0.314
2006 Brown KS, Huang Y, Lu ZY, Jian W, Blair IA, Whitehead AS. Mild folate deficiency induces a proatherosclerotic phenotype in endothelial cells. Atherosclerosis. 189: 133-41. PMID 16469322 DOI: 10.1016/J.Atherosclerosis.2005.12.018  0.675
2006 Williams MV, Lee SH, Pollack M, Blair IA. Endogenous lipid hydroperoxide-mediated DNA-adduct formation in min mice. The Journal of Biological Chemistry. 281: 10127-33. PMID 16449227 DOI: 10.1074/Jbc.M600178200  0.536
2006 Jiang H, Vudathala DK, Blair IA, Penning TM. Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo[a]pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction. Chemical Research in Toxicology. 19: 68-78. PMID 16411658 DOI: 10.1021/Tx0502488  0.32
2006 Trostchansky A, Lind S, Hodara R, Oe T, Blair IA, Ischiropoulos H, Rubbo H, Souza JM. Interaction with phospholipids modulates alpha-synuclein nitration and lipid-protein adduct formation. The Biochemical Journal. 393: 343-9. PMID 16146428 DOI: 10.1042/Bj20051277  0.519
2005 Yan Y, Weaver VM, Blair IA. Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard. Journal of Proteome Research. 4: 2007-14. PMID 16335945 DOI: 10.1021/Pr050175D  0.341
2005 Jian W, Arora JS, Oe T, Shuvaev VV, Blair IA. Induction of endothelial cell apoptosis by lipid hydroperoxide-derived bifunctional electrophiles. Free Radical Biology & Medicine. 39: 1162-76. PMID 16214032 DOI: 10.1016/J.Freeradbiomed.2005.06.008  0.564
2005 Yu KH, Rustgi AK, Blair IA. Characterization of proteins in human pancreatic cancer serum using differential gel electrophoresis and tandem mass spectrometry. Journal of Proteome Research. 4: 1742-51. PMID 16212428 DOI: 10.1021/Pr050174L  0.318
2005 Yocum AK, Yu K, Oe T, Blair IA. Effect of immunoaffinity depletion of human serum during proteomic investigations. Journal of Proteome Research. 4: 1722-31. PMID 16212426 DOI: 10.1021/Pr0501721  0.663
2005 Lee SH, Williams MV, Blair IA. Targeted chiral lipidomics analysis. Prostaglandins & Other Lipid Mediators. 77: 141-57. PMID 16099399 DOI: 10.1016/J.Prostaglandins.2004.01.009  0.353
2005 Lee SH, Williams MV, Dubois RN, Blair IA. Cyclooxygenase-2-mediated DNA damage. The Journal of Biological Chemistry. 280: 28337-46. PMID 15964853 DOI: 10.1074/Jbc.M504178200  0.349
2005 Lee SH, Arora JA, Oe T, Blair IA. 4-Hydroperoxy-2-nonenal-induced formation of 1,N2-etheno-2'-deoxyguanosine adducts. Chemical Research in Toxicology. 18: 780-6. PMID 15833039 DOI: 10.1021/Tx0497088  0.347
2005 Yocum AK, Oe T, Yergey AL, Blair IA. Novel lipid hydroperoxide-derived hemoglobin histidine adducts as biomarkers of oxidative stress. Journal of Mass Spectrometry : Jms. 40: 754-64. PMID 15827957 DOI: 10.1002/Jms.847  0.684
2005 Jian W, Lee SH, Arora JS, Silva Elipe MV, Blair IA. Unexpected formation of etheno-2'-deoxyguanosine adducts from 5(S)-hydroperoxyeicosatetraenoic acid: evidence for a bis-hydroperoxide intermediate. Chemical Research in Toxicology. 18: 599-610. PMID 15777099 DOI: 10.1021/Tx049693D  0.552
2005 Lee SH, Silva Elipe MV, Arora JS, Blair IA. Dioxododecenoic acid: a lipid hydroperoxide-derived bifunctional electrophile responsible for etheno DNA adduct formation. Chemical Research in Toxicology. 18: 566-78. PMID 15777096 DOI: 10.1021/Tx049716O  0.304
2005 Lee SH, Oe T, Arora JS, Blair IA. Analysis of FeII-mediated decomposition of a linoleic acid-derived lipid hydroperoxide by liquid chromatography/mass spectrometry. Journal of Mass Spectrometry : Jms. 40: 661-8. PMID 15739161 DOI: 10.1002/Jms.838  0.306
2005 Williams MV, Lee SH, Blair IA. Liquid chromatography/mass spectrometry analysis of bifunctional electrophiles and DNA adducts from vitamin C mediated decomposition of 15-hydroperoxyeicosatetraenoic acid. Rapid Communications in Mass Spectrometry : Rcm. 19: 849-58. PMID 15723435 DOI: 10.1002/Rcm.1854  0.344
2003 Lee SH, Williams MV, DuBois RN, Blair IA. Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 17: 2168-76. PMID 14515314 DOI: 10.1002/Rcm.1170  0.341
2003 Oe T, Arora JS, Lee SH, Blair IA. A novel lipid hydroperoxide-derived cyclic covalent modification to histone H4. The Journal of Biological Chemistry. 278: 42098-105. PMID 12930824 DOI: 10.1074/Jbc.M308167200  0.326
2003 Pollack M, Oe T, Lee SH, Silva Elipe MV, Arison BH, Blair IA. Characterization of 2'-deoxycytidine adducts derived from 4-oxo-2-nonenal, a novel lipid peroxidation product. Chemical Research in Toxicology. 16: 893-900. PMID 12870892 DOI: 10.1021/Tx030009P  0.484
2002 Palackal NT, Lee SH, Harvey RG, Blair IA, Penning TM. Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells. The Journal of Biological Chemistry. 277: 24799-808. PMID 11978787 DOI: 10.1074/Jbc.M112424200  0.326
2002 Blair IA. Lipid hydroperoxide-mediated DNA damage. Experimental Gerontology. 36: 1473-81. PMID 11525870 DOI: 10.1016/S0531-5565(01)00133-4  0.306
2002 Palackal NT, Lee SH, Harvey RG, Blair IA, Penning TM. Human AKR1C isoforms oxidize the potent proximate carcinogen 7,12-DMBA-3,4-diol in the human lung A549 carcinoma cell line Polycyclic Aromatic Compounds. 22: 801-810. DOI: 10.1080/10406630290103951  0.303
2001 Pang S, Zheng N, Felix CA, Scavuzzo J, Boston R, Blair IA. Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry. Journal of Mass Spectrometry : Jms. 36: 771-81. PMID 11473400 DOI: 10.1002/Jms.173  0.318
2000 Rindgen D, Lee SH, Nakajima M, Blair IA. Formation of a substituted 1,N(6)-etheno-2'-deoxyadenosine adduct by lipid hydroperoxide-mediated generation of 4-oxo-2-nonenal. Chemical Research in Toxicology. 13: 846-52. PMID 10995257 DOI: 10.1021/Tx0000771  0.314
2000 Lee SH, Rindgen D, Bible RH, Hajdu E, Blair IA. Characterization of 2'-deoxyadenosine adducts derived from 4-oxo-2-nonenal, a novel product of lipid peroxidation. Chemical Research in Toxicology. 13: 565-74. PMID 10898588 DOI: 10.1021/Tx000057Z  0.305
2000 Zhang JY, Fast DM, Schoenhard GL, Arora VK, Belas FJ, Blair IA. Quantitative determination of SC-68328 in dog plasma using flow injection and tandem mass spectrometry. Journal of Mass Spectrometry : Jms. 35: 354-60. PMID 10767764 DOI: 10.1002/(Sici)1096-9888(200003)35:3<354::Aid-Jms942>3.0.Co;2-8  0.307
2000 Xu K, Lanuti M, Lambright ES, Force SD, Albelda SM, Blair IA. A rapid and sensitive method for the quantification of ganciclovir in plasma using liquid chromatography/selected reaction monitoring/mass spectrometry. Biomedical Chromatography : Bmc. 14: 93-8. PMID 10694702 DOI: 10.1002/(Sici)1099-0801(200004)14:2<93::Aid-Bmc932>3.0.Co;2-0  0.301
2000 Fenn PT, Ning C, Segal S, Blair IA. Determination of [(13)C]galactose enrichment in human plasma by gas chromatography/positive chemical ionization tandem mass spectrometry. Journal of Mass Spectrometry : Jms. 35: 218-23. PMID 10679984 DOI: 10.1002/(Sici)1096-9888(200002)35:2<218::Aid-Jms932>3.0.Co;2-8  0.329
2000 Rindgen D, Nakajima M, Wehrli S, Xu K, Blair IA. Covalent modifications to 2'-deoxyguanosine by 4-oxo-2-nonenal, a novel product of lipid peroxidation. Chemical Research in Toxicology. 12: 1195-204. PMID 10604869 DOI: 10.1021/Tx990034O  0.327
1999 Xu K, Arora VK, Chaudhary AK, Cotton RB, Blair IA. Quantitative analysis of cimetidine in human plasma using LC/APCI/SRM/MS Biomedical Chromatography. 13: 455-461. PMID 10534756 DOI: 10.1002/(Sici)1099-0801(199911)13:7<455::Aid-Bmc911>3.0.Co;2-K  0.325
1999 McCoull KD, Rindgen D, Blair IA, Penning TM. Synthesis and characterization of polycyclic aromatic hydrocarbon o- quinone depurinating N7-guanine adducts Chemical Research in Toxicology. 12: 237-246. PMID 10077486 DOI: 10.1021/Tx980182Z  0.309
1996 Goldthwaite CA, Hsieh FY, Womble SW, Nobes BJ, Blair IA, Klunk LJ, Mayol RF. Liquid chromatography/chemical reaction interface mass spectrometry as an alternative to radioisotopes for quantitative drug metabolism studies Analytical Chemistry. 68: 2996-3001. PMID 8794930 DOI: 10.1021/Ac960044J  0.34
1996 Legrand AB, Wang J, Sobo G, Blair IA, Brash AR, Oates JA. Incorporation of 12(S)-hydroxyeicosatetraenoic acid into the phosphatidylcholine signaling pathway. Biochimica Et Biophysica Acta. 1301: 150-60. PMID 8652650 DOI: 10.1016/0005-2760(96)00015-X  0.351
1996 Chaudhary AK, Reddy GR, Blair IA, Marnett LJ. Characterization of an N6-oxopropenyl-2′-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospray ionization tandem mass spectrometry Carcinogenesis. 17: 1167-1170. PMID 8640930 DOI: 10.1093/Carcin/17.5.1167  0.325
1995 Brash AR, Boeglin WE, Capdevila JH, Yeola S, Blair IA. 7-HETE, 10-HETE, and 13-HETE are major products of NADPH-dependent arachidonic acid metabolism in rat liver microsomes: analysis of their stereochemistry, and the stereochemistry of their acid-catalyzed rearrangement. Archives of Biochemistry and Biophysics. 321: 485-92. PMID 7646075 DOI: 10.1006/Abbi.1995.1421  0.329
1995 Chaudhary AK, Nokubo M, Oglesby TD, Marnett LJ, Blair IA. Characterization of endogenous DNA adducts by liquid chromatography/electrospray ionization tandem mass spectrometry Journal of Mass Spectrometry. 30: 1157-1166. DOI: 10.1002/Jms.1190300813  0.313
1994 Beckman JK, Bagheri F, Ji C, Blair IA, Marnett LJ. Phospholipid peroxidation in tumor promoter-exposed mouse skin. Carcinogenesis. 15: 2937-44. PMID 8001259 DOI: 10.1093/Carcin/15.12.2937  0.311
1994 Chaudhary AK, Nokubo M, Marnett LJ, Blair IA. Analysis of the malondialdehyde-2'-deoxyguanosine adduct in rat liver DNA by gas chromatography/electron capture negative chemical ionization mass spectrometry Biological Mass Spectrometry. 23: 457-464. PMID 7918689 DOI: 10.1002/Bms.1200230802  0.32
1993 Homma T, Zhang JY, Shimizu T, Prakash C, Blair IA, Harris RC. Cyclooxygenase-derived metabolites of 8,9-epoxyeicosatrienoic acid are potent mitogens for cultured rat glomerular mesangial cells. Biochemical and Biophysical Research Communications. 191: 282-8. PMID 8447831 DOI: 10.1006/Bbrc.1993.1214  0.316
1992 Christman BW, Gay JC, Christman JW, Prakash C, Blair IA. Analysis of effector cell-derived lyso platelet activating factor by electron capture negative ion mass spectrometry. Biological Mass Spectrometry. 20: 545-52. PMID 1782204 DOI: 10.1002/Bms.1200200907  0.319
1992 Jajoo HK, Capdevila JH, Falck JR, Bhatt RK, Blair IA. Metabolism of 12(R)-hydroxyeicosatetraenoic acid by rat liver microsomes. Biochimica Et Biophysica Acta. 1123: 110-6. PMID 1730042 DOI: 10.1016/0005-2760(92)90177-W  0.325
1992 Prakash C, Zhang JY, Falck JR, Chauhan K, Blair IA. 20-Hydroxyeicosatetraenoic acid is excreted as a glucuronide conjugate in human urine. Biochemical and Biophysical Research Communications. 185: 728-33. PMID 1610364 DOI: 10.1016/0006-291X(92)91686-K  0.317
1991 Morrow JD, Prakash C, Awad JA, Duckworth TA, Zackert WE, Blair IA, Oates JA, Roberts LJ. Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay. Analytical Biochemistry. 193: 142-8. PMID 2042739 DOI: 10.1016/0003-2697(91)90054-W  0.343
1991 Prakash C, Adedoyin A, Wilkinson GR, Blair IA. Enantiospecific quantification of hexobarbital and its metabolites in biological fluids by gas chromatography/electron capture negative ion chemical ionization mass spectrometry. Biological Mass Spectrometry. 20: 559-64. PMID 1782205 DOI: 10.1002/Bms.1200200909  0.321
1990 Jajoo HK, Blair IA, Klunk LJ, Mayol RF. Characterization of in vitro metabolites of the antipsychotic drug tiospirone by mass spectrometry. Biomedical & Environmental Mass Spectrometry. 19: 281-5. PMID 2340363 DOI: 10.1002/Bms.1200190502  0.349
1990 Blair IA. Electron-capture negative-ion chemical ionization mass spectrometry of lipid mediators. Methods in Enzymology. 187: 13-23. PMID 2233337 DOI: 10.1016/0076-6879(90)87004-M  0.363
1990 Jajoo HK, Blair IA, Klunk LJ, Mayol RF. In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 20: 779-86. PMID 2219961 DOI: 10.3109/00498259009046892  0.329
1990 Junier MP, Dray F, Blair I, Capdevila J, Dishman E, Falck JR, Ojeda SR. Epoxygenase products of arachidonic acid are endogenous constituents of the hypothalamus involved in D2 receptor-mediated, dopamine-induced release of somatostatin. Endocrinology. 126: 1534-40. PMID 1968382 DOI: 10.1210/Endo-126-3-1534  0.316
1989 Christman BW, Blair IA. Analysis of platelet activating factor in human saliva by gas chromatography/mass spectrometry. Biomedical & Environmental Mass Spectrometry. 18: 258-64. PMID 2706378 DOI: 10.1002/Bms.1200180409  0.327
1989 Prakash C, Sweetman BJ, Sivakumar R, Taffer IM, Zipkin RE, Blair IA. Preparation of omega trideuterated sulfidopeptide leukotrienes: Analysis by FAB/MS Prostaglandins. 37: 251-258. PMID 2543036 DOI: 10.1016/0090-6980(89)90061-0  0.308
1989 Prakash C, Jajoo HK, Blair IA, Mayol RF. Resolution of enantiomers of the antiarrhythmic drug encainide and its major metabolites by chiral derivatization and high-performance liquid chromatography. Journal of Chromatography. 493: 325-35. PMID 2511218 DOI: 10.1016/S0378-4347(00)82738-3  0.307
1987 Hubbard HL, Eller TD, Mais DE, Halushka PV, Baker RH, Blair IA, Vrbanac JJ, Knapp DR. Extraction of thromboxane B2 from urine using an immobilized antibody column for subsequent analysis by gas chromatography-mass spectrometry. Prostaglandins. 33: 149-60. PMID 3588968 DOI: 10.1016/0090-6980(87)90002-5  0.303
1984 Waddell KA, Barrow SE, Robinson C, Orchard MA, Dollery CT, Blair IA. Quantitative analysis of prostanoids in biological fluids by combined capillary column gas chromatography negative ion chemical ionization mass spectrometry Biomedical Mass Spectrometry. 11: 68-74. PMID 6722282 DOI: 10.1002/Bms.1200110205  0.311
1983 Waddell K, Robinson C, Orchard M, Barrow S, Dollery C, Blair I. Quantitative analysis of arachidonic acid metabolites in complex biological fluids using capillary gas chromatography/negative ion chemical ionisation mass spectrometry International Journal of Mass Spectrometry and Ion Physics. 48: 233-236. DOI: 10.1016/0020-7381(83)87071-5  0.32
1982 HUGGETT AC, BLAIR IA. Detoxification of the putative reactive metabolite of paracetamol with glutathione Biochemical Society Transactions. 10: 519-520. DOI: 10.1042/Bst0100519  0.324
1982 WADDELL KA, BARROW SE, ROBINSON C, ORCHARD MA, DOLLERY CT, BLAIR IA. The simultaneous analysis of prostanoids in biological fluids by combined capillary column gas chromatography and negative-ion chemical-ionization mass spectrometry Biochemical Society Transactions. 10: 518-519. DOI: 10.1042/Bst0100518  0.318
1981 Kahn GC, Boobis AR, Blair IA, Brodie MJ, Davies DS. A radiometric high-pressure liquid chromatography assay for the simultaneous determination of the three main oxidative metabolites of antipyrine in studies in vitro. Analytical Biochemistry. 113: 292-300. PMID 7283135 DOI: 10.1016/0003-2697(81)90080-4  0.332
1973 Barton DHR, Blair IA, Magnus PD, Norris RK. The chemistry of trisulphenamides [N(SR)3]. Part II. Reactions of tribenzenesulphenamide with electron-rich molecules Journal of the Chemical Society, Perkin Transactions 1. 1037-1040. DOI: 10.1039/P19730001037  0.4
1973 Barton DHR, Blair IA, Magnus PD, Norris RK. The chemistry of trisulphenamides [N(SR)3]. Part I. Preparation, thermal decomposition, and reactions of tribenzenesulphenamide [N(SPh) 3] Journal of the Chemical Society, Perkin Transactions 1. 1031-1037. DOI: 10.1039/P19730001031  0.412
1972 Barton DHR, Blair IA, Magnus PD. Ring opening of (-)-pin-2(10)-ene with iodine Journal of the Chemical Society, Perkin Transactions 1. 614-615. DOI: 10.1039/P19720000614  0.397
1972 BARTON DHR, BLAIR IA, MAGNUS PD. ChemInform Abstract: RINGOEFFNUNG VON (-)-DELTA(2,10)-PINEN MIT JOD Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197218179  0.379
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