Derek M. Erion, Ph.D. - Publications

2010 Yale University, New Haven, CT 
Physiology Biology

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Corbit KC, Camporez JPG, Edmunds LR, Tran JL, Vera NB, Erion DM, Deo RC, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ. Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. Diabetes. PMID 29203511 DOI: 10.2337/db17-0524  0.84
2016 Li Z, Erion DM, Maurer TS. Model-Based Assessment of Plasma Citrate Flux Into the Liver: Implications for NaCT as a Therapeutic Target. Cpt: Pharmacometrics & Systems Pharmacology. 5: 132-9. PMID 27069776 DOI: 10.1002/psp4.12062  0.84
2016 Kazierad DJ, Bergman A, Tan B, Erion DM, Somayaji V, Lee DS, Rolph T. Effects of multiple ascending doses of the glucagon receptor antagonist, PF-06291874, in patients with type 2 diabetes mellitus. Diabetes, Obesity & Metabolism. PMID 27059951 DOI: 10.1111/dom.12672  0.84
2016 Talukdar S, Zhou Y, Li D, Rossulek M, Dong J, Somayaji V, Weng Y, Clark R, Lanba A, Owen BM, Brenner MB, Trimmer JK, Gropp KE, Chabot JR, Erion DM, et al. A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects. Cell Metabolism. 23: 427-440. PMID 26959184 DOI: 10.1016/j.cmet.2016.02.001  0.84
2016 Huard K, Gosset JR, Montgomery JI, Gilbert AM, Hayward MM, Magee TV, Cabral S, Uccello DP, Bahnck KB, Brown JA, Purkal J, Gorgoglione MF, Lanba A, Futatsugi K, Herr M, ... ... Erion DM, et al. Optimization of a dicarboxylic series for in vivo inhibition of citrate transport by the solute carrier 13 (SLC13) family. Journal of Medicinal Chemistry. PMID 26734723 DOI: 10.1021/acs.jmedchem.5b01752  0.84
2016 Erion DM, Park HJ, Lee HY. The role of lipids in the pathogenesis and treatment of type 2 diabetes and associated co-morbidities. Bmb Reports. PMID 26728273 DOI: 10.5483/BMBRep.2016.49.3.268  0.84
2015 Wilson CG, Tran JL, Erion DM, Vera NB, Febbraio M, Weiss EJ. Hepatocyte-specific disruption of CD36 attenuates fatty liver and improves insulin sensitivity in HFD fed mice. Endocrinology. en20151866. PMID 26650570 DOI: 10.1210/en.2015-1866  0.84
2015 Khatun I, Clark RW, Vera NB, Kou K, Erion DM, Coskran T, Bobrowski WF, Okerberg C, Goodwin B. Characterization of a novel intestinal glycerol-3-phosphate acyltransferase pathway and its role in lipid homeostasis. The Journal of Biological Chemistry. PMID 26644473 DOI: 10.1074/jbc.M115.683359  0.84
2015 Huard K, Brown J, Jones JC, Cabral S, Futatsugi K, Gorgoglione M, Lanba A, Vera NB, Zhu Y, Yan Q, Zhou Y, Vernochet C, Riccardi K, Wolford A, Pirman D, ... ... Erion DM, et al. Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5). Scientific Reports. 5: 17391. PMID 26620127 DOI: 10.1038/srep17391  0.84
2015 Futatsugi K, Kung DW, Orr ST, Cabral S, Hepworth D, Aspnes G, Bader S, Bian J, Boehm M, Carpino PA, Coffey SB, Dowling MS, Herr M, Jiao W, Lavergne SY, ... ... Erion DM, et al. Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2). Journal of Medicinal Chemistry. PMID 26349027 DOI: 10.1021/acs.jmedchem.5b01006  0.84
2015 Bernardo B, Lu M, Bandyopadhyay G, Li P, Zhou Y, Huang J, Levin N, Tomas EM, Calle RA, Erion DM, Rolph TP, Brenner M, Talukdar S. FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance. Scientific Reports. 5: 11382. PMID 26153793 DOI: 10.1038/srep11382  0.84
2014 Erion DM, Lapworth A, Amor PA, Bai G, Vera NB, Clark RW, Yan Q, Zhu Y, Ross TT, Purkal J, Gorgoglione M, Zhang G, Bonato V, Baker L, Barucci N, et al. The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats. Plos One. 9: e97139. PMID 24858947 DOI: 10.1371/journal.pone.0097139  0.84
2014 Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 510: 542-6. PMID 24847880 DOI: 10.1038/nature13270  0.84
2014 Hall AM, Soufi N, Chambers KT, Chen Z, Schweitzer GG, McCommis KS, Erion DM, Graham MJ, Su X, Finck BN. Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice. Diabetes. 63: 2284-96. PMID 24595352 DOI: 10.2337/db13-1502  0.84
2014 Neuschäfer-Rube F, Lieske S, Kuna M, Henkel J, Perry RJ, Erion DM, Pesta D, Willmes DM, Brachs S, von Loeffelholz C, Tolkachov A, Schupp M, Pathe-Neuschäfer-Rube A, Pfeiffer AF, Shulman GI, et al. The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes. Diabetes. 63: 1048-57. PMID 24222346 DOI: 10.2337/db13-0749  0.84
2013 Vatner DF, Weismann D, Beddow SA, Kumashiro N, Erion DM, Liao XH, Grover GJ, Webb P, Phillips KJ, Weiss RE, Bogan JS, Baxter J, Shulman GI, Samuel VT. Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways. American Journal of Physiology. Endocrinology and Metabolism. 305: E89-100. PMID 23651850 DOI: 10.1152/ajpendo.00573.2012  0.84
2013 Erion DM, Kotas ME, McGlashon J, Yonemitsu S, Hsiao JJ, Nagai Y, Iwasaki T, Murray SF, Bhanot S, Cline GW, Samuel VT, Shulman GI, Gillum MP. cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis. The Journal of Biological Chemistry. 288: 16167-76. PMID 23595987 DOI: 10.1074/jbc.M113.460246  0.84
2013 Kumashiro N, Yoshimura T, Cantley JL, Majumdar SK, Guebre-Egziabher F, Kursawe R, Vatner DF, Fat I, Kahn M, Erion DM, Zhang XM, Zhang D, Manchem VP, Bhanot S, Gerhard GS, et al. Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats Hepatology. 57: 1763-1772. PMID 23175050 DOI: 10.1002/hep.26170  0.84
2013 Erion DM, Popov V, Hsiao JJ, Vatner D, Mitchell K, Yonemitsu S, Nagai Y, Kahn M, Gillum MP, Dong J, Murray SF, Manchem VP, Bhanot S, Cline GW, Shulman GI, et al. The role of the carbohydrate response element-binding protein in male fructose-fed rats Endocrinology. 154: 36-44. PMID 23161873 DOI: 10.1210/en.2012-1725  0.84
2012 Brown WH, Gillum MP, Lee HY, Camporez JP, Zhang XM, Jeong JK, Alves TC, Erion DM, Guigni BA, Kahn M, Samuel VT, Cravatt BF, Diano S, Shulman GI. Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. Proceedings of the National Academy of Sciences of the United States of America. 109: 14966-71. PMID 22912404 DOI: 10.1073/pnas.1212887109  0.84
2011 Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, et al. SirT1 regulates adipose tissue inflammation. Diabetes. 60: 3235-45. PMID 22110092 DOI: 10.2337/db11-0616  0.84
2011 Kumashiro N, Erion DM, Zhang D, Kahn M, Beddow SA, Chu X, Still CD, Gerhard GS, Han X, Dziura J, Petersen KF, Samuel VT, Shulman GI. Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease. Proceedings of the National Academy of Sciences of the United States of America. 108: 16381-5. PMID 21930939 DOI: 10.1073/pnas.1113359108  0.84
2011 Horvath TL, Erion DM, Elsworth JD, Roth RH, Shulman GI, Andrews ZB. GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function. Neurobiology of Disease. 43: 152-62. PMID 21406233 DOI: 10.1016/j.nbd.2011.03.005  0.84
2011 Weismann D, Erion DM, Ignatova-Todorava I, Nagai Y, Stark R, Hsiao JJ, Flannery C, Birkenfeld AL, May T, Kahn M, Zhang D, Yu XX, Murray SF, Bhanot S, Monia BP, et al. Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance Diabetologia. 54: 935-944. PMID 21190014 DOI: 10.1007/s00125-010-1984-5  0.84
2011 Gillum MP, Erion DM, Shulman GI. Sirtuin-1 regulation of mammalian metabolism. Trends in Molecular Medicine. 17: 8-13. PMID 20971038 DOI: 10.1016/j.molmed.2010.09.005  0.84
2010 Erion DM, Shulman GI. Diacylglycerol-mediated insulin resistance. Nature Medicine. 16: 400-2. PMID 20376053 DOI: 10.1038/nm0410-400  0.84
2010 Andrews ZB, Erion DM, Beiler R, Choi CS, Shulman GI, Horvath TL. Uncoupling protein-2 decreases the lipogenic actions of ghrelin. Endocrinology. 151: 2078-86. PMID 20189996 DOI: 10.1210/en.2009-0850  0.84
2009 Erion DM, Ignatova ID, Yonemitsu S, Nagai Y, Chatterjee P, Weismann D, Hsiao JJ, Zhang D, Iwasaki T, Stark R, Flannery C, Kahn M, Carmean CM, Yu XX, Murray SF, et al. Prevention of Hepatic Steatosis and Hepatic Insulin Resistance by Knockdown of cAMP Response Element-Binding Protein Cell Metabolism. 10: 499-506. PMID 19945407 DOI: 10.1016/j.cmet.2009.10.007  0.84
2009 Andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, Elsworth JD, Savitt JM, DiMarchi R, Tschoep M, Roth RH, Gao XB, Horvath TL. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14057-65. PMID 19906954 DOI: 10.1523/JNEUROSCI.3890-09.2009  0.84
2009 Erion DM, Yonemitsu S, Nie Y, Nagai Y, Gillum MP, Hsiao JJ, Iwasaki T, Stark R, Weismann D, Yu XX, Murray SF, Bhanot S, Monia BP, Horvath TL, Gao Q, et al. SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats. Proceedings of the National Academy of Sciences of the United States of America. 106: 11288-93. PMID 19549853 DOI: 10.1073/pnas.0812931106  0.84
2009 Nie Y, Erion DM, Yuan Z, Dietrich M, Shulman GI, Horvath TL, Gao Q. STAT3 inhibition of gluconeogenesis is downregulated by SirT1. Nature Cell Biology. 11: 492-500. PMID 19295512 DOI: 10.1038/ncb1857  0.84
2009 Nagai Y, Yonemitsu S, Erion DM, Iwasaki T, Stark R, Weismann D, Dong J, Zhang D, Jurczak MJ, Löffler MG, Cresswell J, Yu XX, Murray SF, Bhanot S, Monia BP, et al. The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance. Cell Metabolism. 9: 252-64. PMID 19254570 DOI: 10.1016/j.cmet.2009.01.011  0.84
2008 Gillum MP, Zhang D, Zhang XM, Erion DM, Jamison RA, Choi C, Dong J, Shanabrough M, Duenas HR, Frederick DW, Hsiao JJ, Horvath TL, Lo CM, Tso P, Cline GW, et al. N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake. Cell. 135: 813-24. PMID 19041747 DOI: 10.1016/j.cell.2008.10.043  0.84
2008 Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature. 454: 846-51. PMID 18668043 DOI: 10.1038/nature07181  0.84
2004 Parcher BW, Erion DM, Dang Q. An efficient synthesis of 5-aminoimidazol-2-ones via cyclization reactions of 12-aminoacetonitriles and isocyanates Tetrahedron Letters. 45: 2677-2679. DOI: 10.1016/j.tetlet.2004.01.088  0.84
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