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Denis V. Titov - Publications

Affiliations: 
Pharmacology and Molecular Sciences Johns Hopkins University School of Medicine, Baltimore, MD, United States 
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Choe M, Ekvik AE, Stalnaker G, Shin HR, Titov DV. Genetically encoded tool for manipulation of ΔΨm identifies its role as the driver of ISR induced by ATP synthase dysfunction. Cell Chemical Biology. 32: 620-630.e6. PMID 40250406 DOI: 10.1016/j.chembiol.2025.03.007  0.322
2023 Choe M, Titov DV. Genetically encoded tool for manipulation of ΔΨm identifies the latter as the driver of integrative stress response induced by ATP Synthase dysfunction. Biorxiv : the Preprint Server For Biology. PMID 38234735 DOI: 10.1101/2023.12.27.573435  0.319
2020 Mick E, Titov DV, Skinner OS, Sharma R, Jourdain AA, Mootha VK. Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell. Elife. 9. PMID 32463360 DOI: 10.7554/Elife.49178  0.685
2020 Mick E, Titov DV, Skinner OS, Sharma R, Jourdain AA, Mootha VK. Author response: Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell Elife. DOI: 10.7554/Elife.49178.Sa2  0.645
2017 Cracan V, Titov DV, Shen H, Grabarek Z, Mootha VK. A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells. Nature Chemical Biology. PMID 28805804 DOI: 10.1038/Nchembio.2454  0.647
2016 Titov DV, Cracan V, Goodman RP, Peng J, Grabarek Z, Mootha VK. Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio. Science (New York, N.Y.). 352: 231-5. PMID 27124460 DOI: 10.1126/Science.Aad4017  0.606
2016 Lewis-Smith D, Kamer KJ, Griffin H, Childs AM, Pysden K, Titov D, Duff J, Pyle A, Taylor RW, Yu-Wai-Man P, Ramesh V, Horvath R, Mootha VK, Chinnery PF. Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood. Neurology. Genetics. 2: e59. PMID 27123478 DOI: 10.1212/Nxg.0000000000000059  0.461
2016 Cracan V, Titov D, Grabarek Z, Mootha V. Genetically Encoded Tools for Compartment-Specific Manipulation of NAD+/NADH or NADP+/NADPH Ratios Free Radical Biology and Medicine. 100: S182. DOI: 10.1016/J.Freeradbiomed.2016.10.479  0.572
2015 He QL, Titov DV, Li J, Tan M, Ye Z, Zhao Y, Romo D, Liu JO. Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide. Angewandte Chemie (International Ed. in English). 54: 1859-63. PMID 25504624 DOI: 10.1002/Anie.201408817  0.636
2012 Titov DV, Liu JO. Identification and validation of protein targets of bioactive small molecules. Bioorganic & Medicinal Chemistry. 20: 1902-9. PMID 22226983 DOI: 10.1016/J.Bmc.2011.11.070  0.347
2011 Titov DV, Gilman B, He QL, Bhat S, Low WK, Dang Y, Smeaton M, Demain AL, Miller PS, Kugel JF, Goodrich JA, Liu JO. XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nature Chemical Biology. 7: 182-8. PMID 21278739 DOI: 10.1038/Nchembio.522  0.615
2011 Liu JO, Titov DV, Dang Y, He Q. Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP. Molecular Cell. 41: 131-3. PMID 21255722 DOI: 10.1016/J.Molcel.2011.01.009  0.635
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