Marc Prentki - Publications

Biochemistry Université de Montréal, Montréal, Canada 
Animal Physiology Biology, Pharmaceutical Chemistry, Cell Biology, Medicine and Surgery

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Veliova M, Ferreira CM, Benador IY, Jones AE, Mahdaviani K, Brownstein AJ, Desousa BR, Acín-Pérez R, Petcherski A, Assali EA, Stiles L, Divakaruni AS, Prentki M, Corkey BE, Liesa M, et al. Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling. Embo Reports. e49634. PMID 33275313 DOI: 10.15252/embr.201949634  0.4
2020 Poursharifi P, Attané C, Mugabo Y, Al-Mass A, Ghosh A, Schmitt C, Zhao S, Guida J, Lussier R, Erb H, Chenier I, Peyot ML, Joly E, Noll C, Carpentier AC, ... ... Prentki M, et al. Adipose ABHD6 regulates tolerance to cold and thermogenic programs. Jci Insight. PMID 33201859 DOI: 10.1172/jci.insight.140294  0.52
2020 Mohamed AF, Ghosh A, Al-Khairi I, Madiraju SRM, Abubakr J, Prentki M. The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation. Progress in Lipid Research. 101067. PMID 33011191 DOI: 10.1016/j.plipres.2020.101067  0.52
2020 Prentki M, Peyot ML, Masiello P, Madiraju SRM. Nutrient-Induced Metabolic Stress, Adaptation, Detoxification, and Toxicity in the Pancreatic β-Cell. Diabetes. 69: 279-290. PMID 32079704 DOI: 10.2337/dbi19-0014  0.52
2019 Prentki M, Corkey BE, Madiraju SRM. Lipid-associated metabolic signalling networks in pancreatic beta cell function. Diabetologia. PMID 31423551 DOI: 10.1007/s00125-019-04976-w  0.52
2019 Nolan CJ, Prentki M. Insulin resistance and insulin hypersecretion in the metabolic syndrome and type 2 diabetes: Time for a conceptual framework shift. Diabetes & Vascular Disease Research. 1479164119827611. PMID 30770030 DOI: 10.1177/1479164119827611  0.48
2018 Sanchez-Parra C, Jacovetti C, Dumortier O, Lee K, Peyot ML, Guay C, Prentki M, Laybutt DR, Van Obberghen E, Regazzi R. Contribution of the Long Non-Coding RNA H19 to Neonatal and Adult Rodent β-Cell Mass Expansion. Diabetes. PMID 30115652 DOI: 10.2337/db18-0201  0.48
2017 Motterle A, Gattesco S, Peyot ML, Esguerra JLS, Gomez-Ruiz A, Laybutt DR, Gilon P, Burdet F, Ibberson M, Eliasson L, Prentki M, Regazzi R. Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes. Molecular Metabolism. 6: 1407-1418. PMID 29107288 DOI: 10.1016/j.molmet.2017.08.005  0.48
2017 Lamontagne J, Al-Mass A, Nolan CJ, Corkey BE, Madiraju SRM, Joly E, Prentki M. Identification of the signals for glucose-induced insulin secretion in INS1 (832/13) β-cells using metformin-induced metabolic deceleration as a model. The Journal of Biological Chemistry. PMID 28972173 DOI: 10.1074/jbc.M117.808105  0.52
2017 Poursharifi P, Madiraju SRM, Prentki M. Monoacylglycerol signalling and ABHD6 in health and disease. Diabetes, Obesity & Metabolism. 19: 76-89. PMID 28880480 DOI: 10.1111/dom.13008  0.52
2017 Possik E, Madiraju SRM, Prentki M. Glycerol-3-phosphate phosphatase/PGP: Role in intermediate metabolism and target for cardiometabolic diseases. Biochimie. PMID 28826615 DOI: 10.1016/j.biochi.2017.08.001  0.52
2017 Mugabo Y, Zhao S, Lamontagne J, Al-Mass A, Peyot ML, Corkey BE, Joly E, Madiraju SR, Prentki M. Metabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells. The Journal of Biological Chemistry. PMID 28280244 DOI: 10.1074/jbc.M116.763060  0.48
2016 Fisette A, Tobin S, Décarie-Spain L, Bouyakdan K, Peyot ML, Madiraju SR, Prentki M, Fulton S, Alquier T. α/β-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility. Cell Reports. 17: 1217-1226. PMID 27783937 DOI: 10.1016/j.celrep.2016.10.004  0.48
2016 Attané C, Peyot ML, Lussier R, Poursharifi P, Zhao S, Zhang D, Morin J, Pineda M, Wang S, Dumortier O, Ruderman NB, Mitchell GA, Simons B, Madiraju SR, Joly E, ... Prentki M, et al. A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice. Diabetologia. PMID 27677764 DOI: 10.1007/s00125-016-4105-2  0.56
2016 Attané C, Peyot ML, Lussier R, Zhang D, Joly E, Madiraju SR, Prentki M. Differential Insulin Secretion of High-Fat Diet-Fed C57BL/6NN and C57BL/6NJ Mice: Implications of Mixed Genetic Background in Metabolic Studies. Plos One. 11: e0159165. PMID 27403868 DOI: 10.1371/journal.pone.0159165  0.56
2016 Pepin É, Al-Mass A, Attané C, Zhang K, Lamontagne J, Lussier R, Madiraju SR, Joly E, Ruderman NB, Sladek R, Prentki M, Peyot ML. Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression. Plos One. 11: e0153017. PMID 27043434 DOI: 10.1371/journal.pone.0153017  0.56
2016 Zhao S, Mugabo Y, Ballentine G, Attane C, Iglesias J, Poursharifi P, Zhang D, Nguyen TA, Erb H, Prentki R, Peyot ML, Joly E, Tobin S, Fulton S, Brown JM, ... ... Prentki M, et al. α/β-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes. Cell Reports. PMID 26997277 DOI: 10.1016/j.celrep.2016.02.076  0.56
2016 Kim-Muller JY, Kim YJ, Fan J, Zhao S, Banks AS, Prentki M, Accili D. FoxO1 Deacetylation Decreases Fatty Acid Oxidation in beta-cells and Sustains Insulin Secretion in Diabetes. The Journal of Biological Chemistry. PMID 26984405 DOI: 10.1074/jbc.M115.705608  0.56
2016 Mugabo Y, Zhao S, Seifried A, Gezzar S, Al-Mass A, Zhang D, Lamontagne J, Attane C, Poursharifi P, Iglesias J, Joly E, Peyot ML, Gohla A, Madiraju SR, Prentki M. Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26755581 DOI: 10.1073/pnas.1514375113  0.56
2015 Zhao S, Poursharifi P, Mugabo Y, Levens EJ, Vivot K, Attane C, Iglesias J, Peyot ML, Joly E, Madiraju SR, Prentki M. α/β-Hydrolase domain-6 and saturated long chain monoacylglycerol regulate insulin secretion promoted by both fuel and non-fuel stimuli. Molecular Metabolism. 4: 940-50. PMID 26909310 DOI: 10.1016/j.molmet.2015.09.012  0.52
2015 Iglesias J, Lamontagne J, Erb H, Gezzar S, Zhao S, Joly E, Truong VL, Skorey K, Crane S, Madiraju SR, Prentki M. Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of of known inhibitors. Journal of Lipid Research. PMID 26423520 DOI: 10.1194/jlr.D058438  0.56
2015 Nolan CJ, Ruderman NB, Kahn SE, Pedersen O, Prentki M. Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686. Diabetes. 64: e38-9. PMID 26405280 DOI: 10.2337/dbi15-0002  0.56
2015 Jacovetti C, Jimenez V, Ayuso E, Laybutt R, Peyot ML, Prentki M, Bosch F, Regazzi R. Contribution of Intronic miR-338-3p and Its Hosting Gene AATK to Compensatory β-Cell Mass Expansion. Molecular Endocrinology (Baltimore, Md.). 29: 693-702. PMID 25751313 DOI: 10.1210/me.2014-1299  0.56
2015 Nolan CJ, Ruderman NB, Kahn SE, Pedersen O, Prentki M. Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes. Diabetes. 64: 673-86. PMID 25713189 DOI: 10.2337/db14-0694  0.48
2014 Fergusson G, Ethier M, Guévremont M, Chrétien C, Attané C, Joly E, Fioramonti X, Prentki M, Poitout V, Alquier T. Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice. Molecular Metabolism. 3: 848-54. PMID 25506550 DOI: 10.1016/j.molmet.2014.09.006  0.56
2014 Kim-Muller JY, Zhao S, Srivastava S, Mugabo Y, Noh HL, Kim YR, Madiraju SR, Ferrante AW, Skolnik EY, Prentki M, Accili D. Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice. Cell Metabolism. 20: 593-602. PMID 25264246 DOI: 10.1016/j.cmet.2014.08.012  0.56
2014 Gauthier MS, Pérusse JR, Lavoie MÈ, Sladek R, Madiraju SR, Ruderman NB, Coulombe B, Prentki M, Rabasa-Lhoret R. Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals. The Journal of Clinical Endocrinology and Metabolism. 99: E2518-28. PMID 25210878 DOI: 10.1210/jc.2014-1662  0.56
2014 Zhao S, Mugabo Y, Iglesias J, Xie L, Delghingaro-Augusto V, Lussier R, Peyot ML, Joly E, Taïb B, Davis MA, Brown JM, Abousalham A, Gaisano H, Madiraju SR, Prentki M. α/β-Hydrolase domain-6-accessible monoacylglycerol controls glucose-stimulated insulin secretion. Cell Metabolism. 19: 993-1007. PMID 24814481 DOI: 10.1016/j.cmet.2014.04.003  0.56
2014 Zarrouki B, Benterki I, Fontés G, Peyot ML, Seda O, Prentki M, Poitout V. Epidermal growth factor receptor signaling promotes pancreatic β-cell proliferation in response to nutrient excess in rats through mTOR and FOXM1. Diabetes. 63: 982-93. PMID 24194502 DOI: 10.2337/db13-0425  0.56
2013 Nolan CJ, Ruderman NB, Prentki M. Intensive insulin for type 2 diabetes: the risk of causing harm. The Lancet. Diabetes & Endocrinology. 1: 9-10. PMID 24622256 DOI: 10.1016/S2213-8587(13)70027-5  0.56
2013 Guay C, Joly E, Pepin E, Barbeau A, Hentsch L, Pineda M, Madiraju SR, Brunengraber H, Prentki M. A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells. Plos One. 8: e77097. PMID 24130841 DOI: 10.1371/journal.pone.0077097  0.56
2013 Ruderman NB, Carling D, Prentki M, Cacicedo JM. AMPK, insulin resistance, and the metabolic syndrome. The Journal of Clinical Investigation. 123: 2764-72. PMID 23863634 DOI: 10.1172/JCI67227  0.56
2013 Nesca V, Guay C, Jacovetti C, Menoud V, Peyot ML, Laybutt DR, Prentki M, Regazzi R. Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes. Diabetologia. 56: 2203-12. PMID 23842730 DOI: 10.1007/s00125-013-2993-y  0.56
2013 Prentki M, Matschinsky FM, Madiraju SR. Metabolic signaling in fuel-induced insulin secretion. Cell Metabolism. 18: 162-85. PMID 23791483 DOI: 10.1016/j.cmet.2013.05.018  0.56
2013 Rancoule C, Attané C, Grès S, Fournel A, Dusaulcy R, Bertrand C, Vinel C, Tréguer K, Prentki M, Valet P, Saulnier-Blache JS. Lysophosphatidic acid impairs glucose homeostasis and inhibits insulin secretion in high-fat diet obese mice. Diabetologia. 56: 1394-402. PMID 23508306 DOI: 10.1007/s00125-013-2891-3  0.56
2013 Lamontagne J, Jalbert-Arsenault E, Pepin E, Peyot ML, Ruderman NB, Nolan CJ, Joly E, Madiraju SR, Poitout V, Prentki M. Pioglitazone acutely reduces energy metabolism and insulin secretion in rats. Diabetes. 62: 2122-9. PMID 23378607 DOI: 10.2337/db12-0428  0.56
2012 Iglesias J, Barg S, Vallois D, Lahiri S, Roger C, Yessoufou A, Pradevand S, McDonald A, Bonal C, Reimann F, Gribble F, Debril MB, Metzger D, Chambon P, Herrera P, ... ... Prentki M, et al. PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice. The Journal of Clinical Investigation. 122: 4105-17. PMID 23093780 DOI: 10.1172/JCI42127  0.56
2012 Jacovetti C, Abderrahmani A, Parnaud G, Jonas JC, Peyot ML, Cornu M, Laybutt R, Meugnier E, Rome S, Thorens B, Prentki M, Bosco D, Regazzi R. MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity. The Journal of Clinical Investigation. 122: 3541-51. PMID 22996663 DOI: 10.1172/JCI64151  0.56
2012 Talbot J, Joly E, Prentki M, Buteau J. β-Arrestin1-mediated recruitment of c-Src underlies the proliferative action of glucagon-like peptide-1 in pancreatic β INS832/13 cells. Molecular and Cellular Endocrinology. 364: 65-70. PMID 22939843 DOI: 10.1016/j.mce.2012.08.010  0.56
2012 Ferdaoussi M, Bergeron V, Zarrouki B, Kolic J, Cantley J, Fielitz J, Olson EN, Prentki M, Biden T, MacDonald PE, Poitout V. G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1. Diabetologia. 55: 2682-92. PMID 22820510 DOI: 10.1007/s00125-012-2650-x  0.56
2012 Prentki M, Madiraju SR. Glycerolipid/free fatty acid cycle and islet β-cell function in health, obesity and diabetes. Molecular and Cellular Endocrinology. 353: 88-100. PMID 22108437 DOI: 10.1016/j.mce.2011.11.004  0.56
2012 Delghingaro-Augusto V, Décary S, Peyot ML, Latour MG, Lamontagne J, Paradis-Isler N, Lacharité-Lemieux M, Akakpo H, Birot O, Nolan CJ, Prentki M, Bergeron R. Voluntary running exercise prevents β-cell failure in susceptible islets of the Zucker diabetic fatty rat. American Journal of Physiology. Endocrinology and Metabolism. 302: E254-64. PMID 22045312 DOI: 10.1152/ajpendo.00360.2011  0.56
2011 Tiano JP, Delghingaro-Augusto V, Le May C, Liu S, Kaw MK, Khuder SS, Latour MG, Bhatt SA, Korach KS, Najjar SM, Prentki M, Mauvais-Jarvis F. Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes. The Journal of Clinical Investigation. 121: 3331-42. PMID 21747171 DOI: 10.1172/JCI44564  0.56
2011 Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet (London, England). 378: 169-81. PMID 21705072 DOI: 10.1016/S0140-6736(11)60614-4  0.56
2010 Pepin E, Guay C, Delghingaro-Augusto V, Joly E, Madiraju SR, Prentki M. Short-chain 3-hydroxyacyl-CoA dehydrogenase is a negative regulator of insulin secretion in response to fuel and non-fuel stimuli in INS832/13 β-cells. Journal of Diabetes. 2: 157-67. PMID 20923481 DOI: 10.1111/j.1753-0407.2010.00076.x  0.56
2010 Fontés G, Zarrouki B, Hagman DK, Latour MG, Semache M, Roskens V, Moore PC, Prentki M, Rhodes CJ, Jetton TL, Poitout V. Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass Diabetologia. 53: 2369-2379. PMID 20628728 DOI: 10.1007/s00125-010-1850-5  0.56
2010 Peyot ML, Pepin E, Lamontagne J, Latour MG, Zarrouki B, Lussier R, Pineda M, Jetton TL, Madiraju SR, Joly E, Prentki M. Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass. Diabetes. 59: 2178-87. PMID 20547980 DOI: 10.2337/db09-1452  0.56
2010 El-Assaad W, Joly E, Barbeau A, Sladek R, Buteau J, Maestre I, Pepin E, Zhao S, Iglesias J, Roche E, Prentki M. Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells. Endocrinology. 151: 3061-73. PMID 20444946 DOI: 10.1210/en.2009-1238  0.56
2010 Haddad P, Martineau L, Spoor D, Leduc C, Benhaddou-Andaloussi A, Joly E, Prentki M, Harris C, Bennett S, Burt A, Arnason J. In-vitro evaluation of the anti-diabetic potential of plants identified through an ethnobotanical survey of the Cree Nation of Mistissini in Northern Quebec Focus On Alternative and Complementary Therapies. 10: 24-24. DOI: 10.1111/j.2042-7166.2005.tb00483.x  0.48
2009 Joly E, Roduit R, Peyot ML, Habinowski SA, Ruderman NB, Witters LA, Prentki M. Glucose represses PPARα gene expression via AMP-activated protein kinase but not via p38 mitogen-activated protein kinase in the pancreatic β-cell. Journal of Diabetes. 1: 263-72. PMID 20923527 DOI: 10.1111/j.1753-0407.2009.00043.x  0.56
2009 Ntimbane T, Comte B, Mailhot G, Berthiaume Y, Poitout V, Prentki M, Rabasa-Lhoret R, Levy E. Cystic fibrosis-related diabetes: from CFTR dysfunction to oxidative stress. The Clinical Biochemist. Reviews / Australian Association of Clinical Biochemists. 30: 153-77. PMID 20011209  0.48
2009 Madiraju P, Pande SV, Prentki M, Madiraju SR. Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation. Epigenetics. 4: 399-403. PMID 19755853 DOI: 10.4161/epi.4.6.9767  0.56
2009 Rung J, Cauchi S, Albrechtsen A, Shen L, Rocheleau G, Cavalcanti-Proença C, Bacot F, Balkau B, Belisle A, Borch-Johnsen K, Charpentier G, Dina C, Durand E, Elliott P, Hadjadj S, ... ... Prentki M, et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nature Genetics. 41: 1110-5. PMID 19734900 DOI: 10.1038/ng.443  0.56
2009 Alquier T, Peyot ML, Latour MG, Kebede M, Sorensen CM, Gesta S, Ronald Kahn C, Smith RD, Jetton TL, Metz TO, Prentki M, Poitout V. Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets. Diabetes. 58: 2607-15. PMID 19720802 DOI: 10.2337/db09-0362  0.56
2009 Peyot ML, Gray JP, Lamontagne J, Smith PJ, Holz GG, Madiraju SR, Prentki M, Heart E. Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. Plos One. 4: e6221. PMID 19593440 DOI: 10.1371/journal.pone.0006221  0.56
2009 Bendayan M, Londono I, Kemp BE, Hardie GD, Ruderman N, Prentki M. Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 57: 963-71. PMID 19581628 DOI: 10.1369/jhc.2009.954016  0.56
2009 Harbilas D, Martineau LC, Harris CS, Adeyiwola-Spoor DC, Saleem A, Lambert J, Caves D, Johns T, Prentki M, Cuerrier A, Arnason JT, Bennett SA, Haddad PS. Evaluation of the antidiabetic potential of selected medicinal plant extracts from the Canadian boreal forest used to treat symptoms of diabetes: part II. Canadian Journal of Physiology and Pharmacology. 87: 479-92. PMID 19526043 DOI: 10.1139/y09-029  0.56
2009 Lamontagne J, Pepin E, Peyot ML, Joly E, Ruderman NB, Poitout V, Madiraju SR, Nolan CJ, Prentki M. Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrations. Endocrinology. 150: 3465-74. PMID 19406947 DOI: 10.1210/en.2008-1557  0.56
2009 Peyot ML, Guay C, Latour MG, Lamontagne J, Lussier R, Pineda M, Ruderman NB, Haemmerle G, Zechner R, Joly E, Madiraju SR, Poitout V, Prentki M. Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion. The Journal of Biological Chemistry. 284: 16848-59. PMID 19389712 DOI: 10.1074/jbc.M109.006650  0.56
2009 Delghingaro-Augusto V, Nolan CJ, Gupta D, Jetton TL, Latour MG, Peshavaria M, Madiraju SRM, Joly E, Peyot ML, Prentki M, Leahy J. Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: Severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass Diabetologia. 52: 1122-1132. PMID 19294363 DOI: 10.1007/s00125-009-1317-8  0.56
2009 Coletta DK, Sriwijitkamol A, Wajcberg E, Tantiwong P, Li M, Prentki M, Madiraju M, Jenkinson CP, Cersosimo E, Musi N, DeFronzo RA. Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: A randomised trial Diabetologia. 52: 723-732. PMID 19169664 DOI: 10.1007/s00125-008-1256-9  0.56
2008 Nolan CJ, Prentki M. The islet beta-cell: fuel responsive and vulnerable. Trends in Endocrinology and Metabolism: Tem. 19: 285-91. PMID 18774732 DOI: 10.1016/j.tem.2008.07.006  0.56
2008 Prentki M, Madiraju SR. Glycerolipid metabolism and signaling in health and disease. Endocrine Reviews. 29: 647-76. PMID 18606873 DOI: 10.1210/er.2008-0007  0.56
2008 Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A. Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Diabetes. 57: 1999-2011. PMID 18458147 DOI: 10.2337/db08-0540  0.56
2008 Maedler K, Schulthess FT, Bielman C, Berney T, Bonny C, Prentki M, Donath MY, Roduit R. Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1905-13. PMID 18263705 DOI: 10.1096/fj.07-101824  0.56
2008 Benhaddou-Andaloussi A, Martineau LC, Spoor D, Vuong T, Leduc C, Joly E, Burt A, Meddah B, Settaf A, Arnason JT, Prentki M, Haddad PS. Antidiabetic activity of Nigella sativa seed extract in cultured pancreatic β-cells, skeletal muscle cells, and adipocytes Pharmaceutical Biology. 46: 96-104. DOI: 10.1080/13880200701734810  0.56
2007 Guay C, Madiraju SR, Aumais A, Joly E, Prentki M. A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion. The Journal of Biological Chemistry. 282: 35657-65. PMID 17928289 DOI: 10.1074/jbc.M707294200  0.56
2007 Przybytkowski E, Joly E, Nolan CJ, Hardy S, Francoeur AM, Langelier Y, Prentki M. Upregulation of cellular triacylglycerol - free fatty acid cycling by oleate is associated with long-term serum-free survival of human breast cancer cells. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 85: 301-10. PMID 17612624 DOI: 10.1139/o07-001  0.56
2007 Lamontagne J, Masiello P, Marcil M, Delghingaro-Augusto V, Burelle Y, Prentki M, Nolan CJ. Circulating lipids are lowered but pancreatic islet lipid metabolism and insulin secretion are unaltered in exercise-trained female rats. Applied Physiology, Nutrition, and Metabolism = Physiologie AppliquéE, Nutrition Et MéTabolisme. 32: 241-8. PMID 17486165 DOI: 10.1139/h06-105  0.56
2007 Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, ... ... Prentki M, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature. 445: 881-5. PMID 17293876 DOI: 10.1038/nature05616  0.56
2006 Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, Prentki M. Fatty acid signaling in the beta-cell and insulin secretion. Diabetes. 55: S16-23. PMID 17130640 DOI: 10.2337/db06-S003  0.56
2006 Spoor DC, Martineau LC, Leduc C, Benhaddou-Andaloussi A, Meddah B, Harris C, Burt A, Fraser MH, Coonishish J, Joly E, Cuerrier A, Bennett SA, Johns T, Prentki M, Arnason JT, et al. Selected plant species from the Cree pharmacopoeia of northern Quebec possess anti-diabetic potential. Canadian Journal of Physiology and Pharmacology. 84: 847-58. PMID 17111029 DOI: 10.1139/y06-018  0.56
2006 Martineau LC, Couture A, Spoor D, Benhaddou-Andaloussi A, Harris C, Meddah B, Leduc C, Burt A, Vuong T, Mai Le P, Prentki M, Bennett SA, Arnason JT, Haddad PS. Anti-diabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium Ait. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 13: 612-23. PMID 16979328 DOI: 10.1016/j.phymed.2006.08.005  0.56
2006 Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, Peyot ML, Fortier M, Guay C, Lamontagne J, Barbeau A, Przybytkowski E, Joly E, Masiello P, Wang S, Mitchell GA, ... Prentki M, et al. Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling. Diabetologia. 49: 2120-30. PMID 16868750 DOI: 10.1007/s00125-006-0305-5  0.56
2006 Prentki M, Nolan CJ. Islet beta cell failure in type 2 diabetes. The Journal of Clinical Investigation. 116: 1802-12. PMID 16823478 DOI: 10.1172/JCI29103  0.56
2006 Kwan EP, Xie L, Sheu L, Nolan CJ, Prentki M, Betz A, Brose N, Gaisano HY. Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance. Diabetes. 55: 1421-9. PMID 16644700 DOI: 10.2337/db05-1263  0.56
2006 Cheyssac C, Dina C, Leprêtre F, Vasseur-Delannoy V, Dechaume A, Lobbens S, Balkau B, Ruiz J, Charpentier G, Pattou F, Joly E, Prentki M, Hansen T, Pedersen O, Vaxillaire M, et al. EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families. Diabetes. 55: 1171-6. PMID 16567544 DOI: 10.2337/diabetes.55.04.06.db05-1298  0.56
2005 Joly E, Bendayan M, Roduit R, Saha AK, Ruderman NB, Prentki M. Malonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes. Febs Letters. 579: 6581-6. PMID 16298369 DOI: 10.1016/j.febslet.2005.10.050  0.56
2005 Hu Z, Dai Y, Prentki M, Chohnan S, Lane MD. A role for hypothalamic malonyl-CoA in the control of food intake. The Journal of Biological Chemistry. 280: 39681-3. PMID 16219771 DOI: 10.1074/jbc.C500398200  0.56
2005 Hu L, Deeney JT, Nolan CJ, Peyot ML, Ao A, Richard AM, Luc E, Faergeman NJ, Knudsen J, Guo W, Sorhede-Winzell M, Prentki M, Corkey BE. Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes. American Journal of Physiology. Endocrinology and Metabolism. 289: E1085-92. PMID 16091387 DOI: 10.1152/ajpendo.00210.2005  0.56
2005 Assifi MM, Suchankova G, Constant S, Prentki M, Saha AK, Ruderman NB. AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. American Journal of Physiology. Endocrinology and Metabolism. 289: E794-800. PMID 15956049 DOI: 10.1152/ajpendo.00144.2005  0.56
2005 Neve B, Fernandez-Zapico ME, Ashkenazi-Katalan V, Dina C, Hamid YH, Joly E, Vaillant E, Benmezroua Y, Durand E, Bakaher N, Delannoy V, Vaxillaire M, Cook T, Dallinga-Thie GM, Jansen H, ... ... Prentki M, et al. Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Proceedings of the National Academy of Sciences of the United States of America. 102: 4807-12. PMID 15774581 DOI: 10.1073/pnas.0409177102  0.56
2005 Park SY, Kim HJ, Wang S, Higashimori T, Dong J, Kim YJ, Cline G, Li H, Prentki M, Shulman GI, Mitchell GA, Kim JK. Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart American Journal of Physiology - Endocrinology and Metabolism. 289: E30-E39. PMID 15701680 DOI: 10.1152/ajpendo.00251.2004  0.56
2005 Hardy S, St-Onge GG, Joly E, Langelier Y, Prentki M. Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40. The Journal of Biological Chemistry. 280: 13285-91. PMID 15695516 DOI: 10.1074/jbc.M410922200  0.56
2005 Pelletier A, Joly E, Prentki M, Coderre L. Adenosine 5'-monophosphate-activated protein kinase and p38 mitogen-activated protein kinase participate in the stimulation of glucose uptake by dinitrophenol in adult cardiomyocytes. Endocrinology. 146: 2285-94. PMID 15677757 DOI: 10.1210/en.2004-1565  0.56
2005 Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG. Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion. Diabetes. 54: 462-71. PMID 15677504 DOI: 10.2337/diabetes.54.2.462  0.56
2005 Gremlich S, Nolan C, Roduit R, Burcelin R, Peyot ML, Delghingaro-Augusto V, Desvergne B, Michalik L, Prentki M, Wahli W. Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation. Endocrinology. 146: 375-82. PMID 15459119 DOI: 10.1210/en.2004-0667  0.56
2004 Rosenberg L, Lipsett M, Yoon JW, Prentki M, Wang R, Jun HS, Pittenger GL, Taylor-Fishwick D, Vinik AI. A pentadecapeptide fragment of islet neogenesis-associated protein increases beta-cell mass and reverses diabetes in C57BL/6J mice. Annals of Surgery. 240: 875-84. PMID 15492571 DOI: 10.1097/01.sla.0000143270.99191.10  0.56
2004 Peyot ML, Nolan CJ, Soni K, Joly E, Lussier R, Corkey BE, Wang SP, Mitchell GA, Prentki M. Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1. Diabetes. 53: 1733-42. PMID 15220197 DOI: 10.2337/diabetes.53.7.1733  0.56
2004 Hartman MG, Lu D, Kim ML, Kociba GJ, Shukri T, Buteau J, Wang X, Frankel WL, Guttridge D, Prentki M, Grey ST, Ron D, Hai T. Role for activating transcription factor 3 in stress-induced beta-cell apoptosis. Molecular and Cellular Biology. 24: 5721-32. PMID 15199129 DOI: 10.1128/MCB.24.13.5721-5732.2004  0.56
2004 Buteau J, El-Assaad W, Rhodes CJ, Rosenberg L, Joly E, Prentki M. Glucagon-like peptide-1 prevents beta cell glucolipotoxicity. Diabetologia. 47: 806-15. PMID 15095038 DOI: 10.1007/s00125-004-1379-6  0.56
2004 Ruderman N, Prentki M. AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. Nature Reviews. Drug Discovery. 3: 340-51. PMID 15060529 DOI: 10.1038/nrd1344  0.56
2004 Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massé F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. Diabetes. 53: 1007-19. PMID 15047616 DOI: 10.2337/diabetes.53.4.1007  0.56
2003 El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R, Hardy S, Joly E, Dbaibo G, Rosenberg L, Prentki M. Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death. Endocrinology. 144: 4154-63. PMID 12933690 DOI: 10.1210/en.2003-0410  0.56
2003 Ruderman NB, Park H, Kaushik VK, Dean D, Constant S, Prentki M, Saha AK. AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise Acta Physiologica Scandinavica. 178: 435-442. PMID 12864749 DOI: 10.1046/j.1365-201X.2003.01164.x  0.56
2003 Hardy S, El-Assaad W, Przybytkowski E, Joly E, Prentki M, Langelier Y. Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells. A role for cardiolipin. The Journal of Biological Chemistry. 278: 31861-70. PMID 12805375 DOI: 10.1074/jbc.M300190200  0.56
2003 Buteau J, Foisy S, Joly E, Prentki M. Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor. Diabetes. 52: 124-32. PMID 12502502 DOI: 10.2337/diabetes.52.1.124  0.56
2003 Maestre I, Jordán J, Calvo S, Reig JA, Ceña V, Soria B, Prentki M, Roche E. Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1. Endocrinology. 144: 335-45. PMID 12488362 DOI: 10.1210/en.2001-211282  0.56
2002 Prentki M, Joly E, El-Assaad W, Roduit R. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. Diabetes. 51: S405-13. PMID 12475783  0.56
2002 Alarcon C, Wicksteed B, Prentki M, Corkey BE, Rhodes CJ. Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation. Diabetes. 51: 2496-504. PMID 12145163  0.56
2002 Park H, Kaushik VK, Constant S, Prentki M, Przybytkowski E, Ruderman NB, Saha AK. Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise. The Journal of Biological Chemistry. 277: 32571-7. PMID 12065578 DOI: 10.1074/jbc.M201692200  0.56
2002 Mason TM, Chan B, El-Bahrani B, Goh T, Gupta N, Gamble J, Qing Shi Z, Prentki M, Steiner G, Giacca A. The effect of chronic insulin delivery via the intraperitoneal versus the subcutaneous route on hepatic triglyceride secretion rate in streptozotocin diabetic rats Atherosclerosis. 161: 345-352. PMID 11888517 DOI: 10.1016/S0021-9150(01)00659-1  0.56
2002 Masiello P, Novelli M, Bombara M, Fierabracci V, Vittorini S, Prentki M, Bergamini E. The antilipolytic agent 3,5-dimethylpyrazole inhibits insulin release in response to both nutrient secretagogues and cyclic adenosine monophosphate agonists in isolated rat islets Metabolism: Clinical and Experimental. 51: 110-114. PMID 11782881 DOI: 10.1053/meta.2002.28969  0.56
2001 Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ, Prentki M. Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation. Diabetes. 50: 2237-43. PMID 11574404 DOI: 10.2337/diabetes.50.10.2237  0.56
2001 Roduit R, Masiello P, Wang SP, Li H, Mitchell GA, Prentki M. A Role for Hormone-Sensitive Lipase in Glucose-Stimulated Insulin Secretion: A Study in Hormone-Sensitive Lipase-Deficient Mice Diabetes. 50: 1970-1975. PMID 11522661  0.56
2001 Lameloise N, Muzzin P, Prentki M, Assimacopoulos-Jeannet F. Uncoupling protein 2: A possible link between fatty acid excess and impaired glucose-induced insulin secretion? Diabetes. 50: 803-809. PMID 11289045  0.56
2001 Caserta F, Tchkonia T, Civelek VN, Prentki M, Brown NF, McGarry JD, Forse RA, Corkey BE, Hamilton JA, Kirkland JL. Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes American Journal of Physiology - Endocrinology and Metabolism. 280. PMID 11158926  0.56
2000 Dillon JS, Yaney GC, Zhou Y, Voilley N, Bowen S, Chipkin S, Bliss CR, Schultz V, Schuit FC, Prentki M, Waxman DJ, Corkey BE. Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells. Diabetes. 49: 2012-20. PMID 11118002  0.56
2000 Hardy S, Langelier Y, Prentki M. Oleate activates phosphatidylinositol 3-kinase and promotes proliferation and reduces apoptosis of MDA-MB-231 breast cancer cells, whereas palmitate has opposite effects. Cancer Research. 60: 6353-8. PMID 11103797  0.56
2000 Roduit R, Morin J, Massé F, Segall L, Roche E, Newgard CB, Assimacopoulos-Jeannet F, Prentki M. Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell. The Journal of Biological Chemistry. 275: 35799-806. PMID 10967113 DOI: 10.1074/jbc.M006001200  0.56
2000 Deeney JT, Prentki M, Corkey BE. Metabolic control of β-cell function Seminars in Cell and Developmental Biology. 11: 267-275. PMID 10966860 DOI: 10.1006/scdb.2000.0175  0.56
2000 Dyck JR, Berthiaume LG, Thomas PD, Kantor PF, Barr AJ, Barr R, Singh D, Hopkins TA, Voilley N, Prentki M, Lopaschuk GD. Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism. The Biochemical Journal. 350: 599-608. PMID 10947976 DOI: 10.1042/0264-6021:3500599  0.56
2000 Farfari S, Schulz V, Corkey B, Prentki M. Glucose-regulated anaplerosis and cataplerosis in pancreatic β cells: Possible implication of a pyruvate/citrate shuttle in insulin secretion Diabetes. 49: 718-726. PMID 10905479  0.56
2000 Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB. Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion Diabetes. 49: 424-430. PMID 10868964  0.56
2000 Saha AK, Schwarsin AJ, Roduit R, Masse F, Kaushik V, Tornheim K, Prentki M, Ruderman NB. Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Journal of Biological Chemistry. 275: 24279-24283. PMID 10854420 DOI: 10.1074/jbc.C000291200  0.56
2000 Deeney JT, Gromada J, Høy M, Olsen HL, Rhodes CJ, Prentki M, Berggren PO, Corkey BE. Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI β-cells) Journal of Biological Chemistry. 275: 9363-9368. PMID 10734079 DOI: 10.1074/jbc.275.13.9363  0.56
2000 Corkey BE, Deeney JT, Yaney GC, Tornheim K, Prentki M. The role of long-chain fatty acyl-CoA esters in β-cell signal transduction Journal of Nutrition. 130. PMID 10721892  0.56
2000 Susini S, Van Haasteren G, Li S, Prentki M, Schlegel W. Essentiality of intron control in the induction of c-fos by glucose and glucoincretin peptides in INS-1 β-cells Faseb Journal. 14: 128-136. PMID 10627287  0.56
1999 Roche E, Buteau J, Aniento I, Reig JA, Soria B, Prentki M. Palmitate and oleate induce the immediate-early response genes c-fos and nur-77 in the pancreatic beta-cell line INS-1. Diabetes. 48: 2007-14. PMID 10512366 DOI: 10.2337/diabetes.48.10.2007  0.56
1999 Segall L, Lameloise N, Assimacopoulos-Jeannet F, Roche E, Corkey P, Thumelin S, Corkey BE, Prentki M. Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells. The American Journal of Physiology. 277: E521-8. PMID 10484365 DOI: 10.1152/ajpendo.1999.277.3.E521  0.56
1999 Buteau J, Roduit R, Susini S, Prentki M. Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells. Diabetologia. 42: 856-64. PMID 10440129 DOI: 10.1007/s001250051238  0.56
1999 Voilley N, Roduit R, Vicaretti R, Bonny C, Waeber G, Dyck JRB, Lopaschuk GD, Prentki M. Cloning and expression of rat pancreatic β-cell malonyl-CoA decarboxylase Biochemical Journal. 340: 213-217. PMID 10229677 DOI: 10.1042/0264-6021:3400213  0.56
1998 Prentki M, Segall L, Roche E, Thumelin S, Brun T, McGarry JD, Corkey BE, Assimacopoulos-Jeannet F. [Gluco-lipotoxicity and gene expression in the pancreatic beta cell]. JournéEs Annuelles De DiabéTologie De L'HôTel-Dieu. 17-27. PMID 9773607  0.56
1998 Susini S, Roche E, Prentki M, Schlegel W. Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, junB, zif-268, and nur-77 gene expression in pancreatic β(INS-1) cells Faseb Journal. 12: 1173-1182. PMID 9737720  0.56
1998 Roche E, Farfari S, Witters LA, Assimacopoulos-Jeannet F, Thumelin S, Brun T, Corkey BE, Saha AK, Prentki M. Long-term exposure of β-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression Diabetes. 47: 1086-1094. PMID 9648832 DOI: 10.2337/diabetes.47.7.1086  0.56
1998 Antinozzi PA, Segall L, Prentki M, McGarry JD, Newgard CB. Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis. The Journal of Biological Chemistry. 273: 16146-54. PMID 9632669 DOI: 10.1074/jbc.273.26.16146  0.56
1997 Prentki M, Tornheim K, Corkey BE. Signal transduction mechanisms in nutrient-induced insulin secretion Diabetologia. 40. PMID 9248699 DOI: 10.1007/s001250051395  0.56
1997 Schuit F, De Vos A, Farfari S, Moens K, Pipeleers D, Brun T, Prentki M. Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in β cells Journal of Biological Chemistry. 272: 18572-18579. PMID 9228023 DOI: 10.1074/jbc.272.30.18572  0.56
1997 Brun T, Assimacopoulos-Jeannet F, Corkey BE, Prentki M. Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic β-cell line INS-1 Diabetes. 46: 393-400. PMID 9032094  0.56
1997 Rochet E, Assimacopoulos-Jeannet F, Witters LA, Perruchoud B, Yaney G, Corkey B, Asfari M, Prentki M. Induction by glucose of genes coding for glycolytic enzymes in a pancreatic β-cell line (INS-1) Journal of Biological Chemistry. 272: 3091-3098. PMID 9006960 DOI: 10.1074/jbc.272.5.3091  0.56
1997 Assimacopoulos-Jeannet F, Thumelin S, Roche E, Esser V, Denis McGarry J, Prentki M. Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic β-cell line INS-1 Journal of Biological Chemistry. 272: 1659-1664. PMID 8999842 DOI: 10.1074/jbc.272.3.1659  0.56
1997 Prentki M, Roche E, Segall L, Brun T, Farfari S, Thumelin S, Jeannet FA, Esser V, Denis McGarry J, Witters L, Yaney G, Sana AK, Corkey B. Glucolipoxia and the etiology of obesity-associated Type 2 diabetes Experimental and Clinical Endocrinology and Diabetes. 105: 89-90.  0.56
1997 Schuit F, De Vos A, Farfari S, Moens K, Pipeleers D, Brun T, Prentki M. Glucose-regulated anaplerosis in rat beta cells Experimental and Clinical Endocrinology and Diabetes. 105.  0.56
1996 Civelek VN, Deeney JT, Shalosky NJ, Tornheim K, Hansford RG, Prentki M, Corkey BE. Regulation of pancreatic β-cell mitochondrial metabolism: Influence of Ca2+, substrate and ADP Biochemical Journal. 318: 615-621. PMID 8809055 DOI: 10.1042/bj3180615  0.56
1996 Prentki M. New insights into pancreatic β-cell metabolic signaling in insulin secretion European Journal of Endocrinology. 134: 272-286. PMID 8616523  0.56
1996 Prentki M, Corkey BE. Are the β-cell signaling molecules malonyl-CoA and cytosolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? Diabetes. 45: 273-283. PMID 8593930  0.56
1996 Brun T, Roche E, Assimacopoulos-Jeannet F, Corkey BE, Kim KH, Prentki M. Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic β-cell nutrient signaling Diabetes. 45: 190-198. PMID 8549864  0.56
1996 Brun T, Assimacopoulos-Jeannel F, Prentki M. Regulation of acetyl-coa carboxylase gene expression by nutrients in the β-cell line INS-1 Faseb Journal. 10.  0.56
1995 Frödin M, Sekine N, Roche E, Filloux C, Prentki M, Wollheim CB, Van Obberghen E. Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting β-cell line, INS-1 Journal of Biological Chemistry. 270: 7882-7889. PMID 7713882  0.56
1994 Prentki M, Brun T, Roche E. Nutriments, insulin secretion and gene expression in the pancreatic beta cell Journees Annuelles De Diabetologie De L"Hotel-Dieu. 1-11. PMID 8051809  0.56
1994 Li SL, Godson C, Roche E, Zhao SJ, Prentki M, Schlegel W. Induction of c-fos in pituitary cells by thyrotrophin-releasing hormone and phorbol 12-myristate 13-acetate depends upon Ca2+ influx Journal of Molecular Endocrinology. 13: 303-312. PMID 7893348  0.56
1994 Roche E, Prentki M. Calcium regulation of immediate-early response genes Cell Calcium. 16: 331-338. PMID 7820853 DOI: 10.1016/0143-4160(94)90097-3  0.56
1993 Werlen G, Belin D, Conne B, Roche E, Lew DP, Prentki M. Intracellular Ca2+ and the regulation of early response gene expression in HL-60 myeloid leukemia cells. The Journal of Biological Chemistry. 268: 16596-601. PMID 8344941  0.56
1993 Brun T, Rochet E, Kim KH, Prentki M. Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic β-cell line (INS-1) Journal of Biological Chemistry. 268: 18905-18911. PMID 8103051  0.56
1992 Prentki M, Vischer S, Glennon MC, Regazzi R, Deeney JT, Corkey BE. Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion Journal of Biological Chemistry. 267: 5802-5810. PMID 1556096  0.56
1992 Deeney JT, Tornheim K, Korchak HM, Prentki M, Corkey BE. Acyl-CoA esters modulate intracellular Ca2+ handling by permeabilized clonal pancreatic β-cells Journal of Biological Chemistry. 267: 19840-19845. PMID 1400300  0.56
1991 Longo EA, Tornheim K, Deeney JT, Varnum BA, Tillotson D, Prentki M, Corkey BE. Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets Journal of Biological Chemistry. 266: 9314-9319. PMID 1902835  0.56
1990 Gilligan A, Prentki M, Knowles BB. EGF receptor down-regulation attenuates ligand-induced second messenger formation Experimental Cell Research. 187: 134-142. PMID 2153564 DOI: 10.1016/0014-4827(90)90127-V  0.56
1990 Ullrich S, Prentki M, Wollheim CB. Somatostatin inhibition of Ca2+-induced insulin secretion in permeabilized HIT-T15 cells Biochemical Journal. 270: 273-276. PMID 1975739  0.56
1989 Corkey BE, Glennon MC, Chen KS, Deeney JT, Matschinsky FM, Prentki M. A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic β-cells Journal of Biological Chemistry. 264: 21608-21612. PMID 2689441  0.56
1989 Geschwind JF, Hiriart M, Glennon MC, Najafi H, Corkey BE, Matschinsky FM, Prentki M. Selective activation of Ca2+ influx by extracellular ATP in a pancreatic beta-cell line (HIT). Biochimica Et Biophysica Acta. 1012: 107-15. PMID 2543452 DOI: 10.1016/0167-4889(89)90018-9  0.56
1989 Matschinsky FM, Corkey BE, Prentki M, Meglasson MD, Erecinska M, Shimizu T, Ghosh A, Parker J. Metabolic connectivity and signalling in pancreatic B-cells Diabetes 1988: Proceedings of the 13th Congress of the International Diabetes Federation. Ics800. 17-26.  0.56
1988 Prentki M, Glennon MC, Thomas AP, Morris RL, Matschinsky FM, Corkey BE. Cell-specific patterns of oscillating free Ca2+ in carbamylcholine-stimulated insulinoma cells. The Journal of Biological Chemistry. 263: 11044-7. PMID 2841314  0.56
1988 Gilligan A, Prentki M, Glennon MC, Knowles BB. Epidermal growth factor-induced increases in inositol trisphosphates, inositol tetrakisphosphates, and cytosolic Ca2+ in a human hepatocellular carcinoma-derived cell line Febs Letters. 233: 41-46. PMID 2838326 DOI: 10.1016/0014-5793(88)81352-8  0.56
1988 Corkey BE, Tornheim K, Deeney JT, Glennon MC, Parker JC, Matschinsky FM, Ruderman NB, Prentki M. Linked oscillations of free Ca2+ and the ATP/ADP ratio in permeabilized RINm5F insulinoma cells supplemented with a glycolyzing cell-free muscle extract. The Journal of Biological Chemistry. 263: 4254-8. PMID 2831225  0.56
1988 Corkey BE, Deeney JT, Glennon MC, Matschinsky FM, Prentki M. Regulation of steady-state free Ca2+ levels by the ATP/ADP ratio and orthophosphate in permeabilized RINm5F insulinoma cells Journal of Biological Chemistry. 263: 4247-4253. PMID 2831224  0.56
1987 Prentki M, Matschinsky FM. Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion Physiological Reviews. 67: 1185-1248. PMID 2825225  0.56
1987 Prentki M, Glennon MC, Geschwind JF, Matschinsky FM, Corkey BE. Cyclic AMP raises cytosolic Ca2+ and promotes Ca2+ influx in a clonal pancreatic β-cell line (HIT T-15) Febs Letters. 220: 103-107. PMID 2440720 DOI: 10.1016/0014-5793(87)80884-0  0.56
1986 Matschinsky FM, Ghosh AK, Meglasson MD, Prentki M, June V, von Allman D. Metabolic concomitants in pure, pancreatic beta cells during glucose-stimulated insulin secretion Journal of Biological Chemistry. 261: 14057-14061. PMID 3533913  0.56
1986 Prentki M, Deeney JT, Matschinsky FM, Joseph SK. Neomycin: a specific drug to study the inositol-phospholipid signalling system? Febs Letters. 197: 285-288. PMID 3485059 DOI: 10.1016/0014-5793(86)80343-X  0.56
1986 Matschinsky FM, Meglasson M, Ghosh A, Appel M, Bedoya F, Prentki M, Corkey B, Shimizu T, Berner D, Najafi H. Biochemical design features of the pancreatic islet cell glucose-sensory system Advances in Experimental Medicine and Biology. 211: 459-469. PMID 3300199  0.56
1985 Falkmer S, Odselius R, Blondel B, Prentki M, Wollheim CB. Energy dispersive X-ray microanalysis of zinc and calcium in organelles of insulin-producing cells of the mouse, rat, and a fish Biomedica Biochimica Acta. 44: 37-43. PMID 3888207  0.56
1985 Gazzano H, Halban P, Prentki M. Identiification of functional insulin receptors on membranes from an insulin-producing cell line (RIN5F) Biochemical Journal. 226: 867-872. PMID 3885941  0.56
1985 Epstein PA, Prentki M, Attie MF. Modulation of intracellular Ca2+ in the parathyroid cell. Release of Ca2+ from non-mitochondrial pools by inositol trisphosphate Febs Letters. 188: 141-144. PMID 3874790 DOI: 10.1016/0014-5793(85)80891-7  0.56
1985 Prentki M, Corkey BE, Matschinsky FM. Inositol 1,4,5-trisphosphate and the endoplasmic reticulum Ca2+ cycle of a rat insulinoma cell line Journal of Biological Chemistry. 260: 9185-9190. PMID 2991236  0.56
1985 Prentki M, Corkey BE, Najafi H, Matschinsky FM. Ca2+ cycling across the endoplasmic reticulum (ER) of rat insulinoma RINm5F cells: Inositol 1,4,5-triphosphate (IP3) infusion studies Federation Proceedings. 44.  0.56
1984 Prentki M, Wollheim CB. Cytosolic free Ca2+ in insulin secreting cells and its regulation by isolated organelles Experientia. 40: 1052-1060. PMID 6436050 DOI: 10.1007/BF01971451  0.56
1984 Prentki M, Wollheim CB, Lew PD. Ca2+ homeostasis in permeabilized human neutrophils. Characterization of Ca2+-sequestering pools and the action of inositol 1,4,5-trisphosphate Journal of Biological Chemistry. 259: 13777-13782. PMID 6334080  0.56
1984 Prentki M, Biden TJ, Janjic D, Irvine RF, Berridge MJ, Wollheim CB. Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate. Nature. 309: 562-4. PMID 6328320 DOI: 10.1038/309562a0  0.56
1984 Prentki M, Janjic D, Wollheim CB. Coordinated regulation of free Ca2+ by isolated organelles from a rat insulinoma Journal of Biological Chemistry. 259: 14054-14058. PMID 6094537  0.56
1984 Biden TJ, Prentki M, Irvine RF, Berridge MJ, Wollheim CB. Inositol 1,4,5-trisphosphate mobilizes intracellular Ca2+ from permeabilized insulin-secreting cells. The Biochemical Journal. 223: 467-73. PMID 6093775  0.56
1984 Prentki M, Janjic D, Biden TJ. Regulation of Ca2+ transport by isolated organelles of a rat insulinoma. Studies with endoplasmic reticulum and secretory granules Journal of Biological Chemistry. 259: 10118-10123. PMID 6088482  0.56
1983 Prentki M, Renold AE. Neutral amino acid transport in isolated rat pancreatic islets Journal of Biological Chemistry. 258: 14239-14244. PMID 6358218  0.56
1983 Prentki M, Janjic D, Wollheim CB. The regulation of extramitochondrial steady state free Ca2+ concentration by rat insulinoma mitochondria Journal of Biological Chemistry. 258: 7597-7602. PMID 6305947  0.56
1982 Assimacopoulos-Jeannet F, McCormack JG, Prentki M, Jeanrenaud B, Denton RM. Parallel increases in rates of fatty acid synthesis and in pyruvate dehydrogenase activity in isolated rat hepatocytes incubated with insulin Bba - General Subjects. 717: 86-90. PMID 7049252 DOI: 10.1016/0304-4165(82)90383-X  0.56
1981 Prentki M, Crettaz M, Jeanrenaud B. Role of microtubules in insulin and glucagon stimulation of amino acid transport in isolated rat hepatocytes Journal of Biological Chemistry. 256: 4336-4340. PMID 6260794  0.56
1980 Crettaz M, Prentki M, Zaninetti D, Jeanrenaud B. Insulin resistance in soleus muscle from obese Zucker rats. Involvement of several defective sites Biochemical Journal. 186: 525-534. PMID 6990920  0.56
1980 Prentki M, Crettaz M, Jeanrenaud B. A possible complementary role of actin microfilaments and microtubules in triacylglycerol secretion by isolated rate hepatocytes Bba - General Subjects. 627: 262-269. DOI: 10.1016/0304-4165(80)90456-0  0.56
1979 Prentki M, Chaponnier C, Jeanrenaud B, Gabbiani G. Actin microfilaments, cell shape, and secretory processes in isolated rat hepatocytes. Effect of phalloidin and cytochalasin D Journal of Cell Biology. 81: 592-607. PMID 572368  0.56
1979 Doi K, Prentki M, Yip C, Muller WA, Jeanrenaud B, Vranic M. Identical biological effects of pancreatic glucagon and a purified moiety of canine gastric immunoreactive glucagon Journal of Clinical Investigation. 63: 525-531. PMID 429572  0.56
1978 Prentki M, Yip CC, Doi K. Comparison of biological effects of pancreatic and stomach glucagon upon isolated rat hepatocytes Diabetologia. 15.  0.56
1978 Gabbiani G, Prentki M, Chaponnier C, Jeanrenaud B. Action of phalloidin, virosin and cytochalasin on isolated rat hepatocytes Journal of Cell Biology. 79.  0.56
1977 Prentki M, Gabbiani G, Jeanrenaud B. Effect of phalloidin and/or microfilaments upon hepatic secretory processes Diabetologia. 13.  0.56
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