Thomas O. Metz, Ph.D. - Publications

Affiliations: 
2003 University of South Carolina, Columbia, SC 
Area:
Biochemistry

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kopczynski D, Ejsing CS, McDonald JG, Bamba T, Baker ES, Bertrand-Michel J, Brügger B, Coman C, Ellis SR, Garrett TJ, Griffiths WJ, Guan XL, Han X, Höring M, Holčapek M, ... ... Metz TO, et al. The Lipidomics Reporting Checklist A framework for transparency of lipidomic experiments and repurposing resource data. Journal of Lipid Research. 100621. PMID 39151590 DOI: 10.1016/j.jlr.2024.100621  0.459
2024 Eisfeld AJ, Anderson LN, Fan S, Walters KB, Halfmann PJ, Westhoff Smith D, Thackray LB, Tan Q, Sims AC, Menachery VD, Schäfer A, Sheahan TP, Cockrell AS, Stratton KG, Webb-Robertson BM, ... ... Metz TO, et al. A compendium of multi-omics data illuminating host responses to lethal human virus infections. Scientific Data. 11: 328. PMID 38565538 DOI: 10.1038/s41597-024-03124-3  0.534
2023 Nakayasu ES, Bramer LM, Ansong C, Schepmoes AA, Fillmore TL, Gritsenko MA, Clauss TR, Gao Y, Piehowski PD, Stanfill BA, Engel DW, Orton DJ, Moore RJ, Qian WJ, Sechi S, ... ... Metz TO, et al. Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity. Cell Reports. Medicine. 101093. PMID 37390828 DOI: 10.1016/j.xcrm.2023.101093  0.64
2023 Hollerbach AL, Ibrahim YM, Meras V, Norheim RV, Huntley AP, Anderson GA, Metz TO, Ewing RG, Smith RD. A Dual-Gated Structures for Lossless Ion Manipulations-Ion Mobility Orbitrap Mass Spectrometry Platform for Combined Ultra-High-Resolution Molecular Analysis. Analytical Chemistry. PMID 37307303 DOI: 10.1021/acs.analchem.3c00881  0.371
2023 Bramer LM, Hontz RD, Eisfeld AJ, Sims AC, Kim YM, Stratton KG, Nicora CD, Gritsenko MA, Schepmoes AA, Akasaka O, Koga M, Tsutsumi T, Nakamura M, Nakachi I, Baba R, ... ... Metz TO, et al. Multi-omics of NET formation and correlations with CNDP1, PSPB, and L-cystine levels in severe and mild COVID-19 infections. Heliyon. 9: e13795. PMID 36915486 DOI: 10.1016/j.heliyon.2023.e13795  0.444
2022 RoyChowdhury T, Bramer LM, Brown J, Kim YM, Zink E, Metz TO, McCue LA, Diefenderfer HL, Bailey V. Soil Metabolomics Predict Microbial Taxa as Biomarkers of Moisture Status in Soils from a Tidal Wetland. Microorganisms. 10. PMID 36014071 DOI: 10.3390/microorganisms10081653  0.43
2022 Colby SM, Chang CH, Bade JL, Nunez JR, Blumer MR, Orton DJ, Bloodsworth KJ, Nakayasu ES, Smith RD, Ibrahim YM, Renslow RS, Metz TO. DEIMoS: An Open-Source Tool for Processing High-Dimensional Mass Spectrometry Data. Analytical Chemistry. 94: 6130-6138. PMID 35430813 DOI: 10.1021/acs.analchem.1c05017  0.358
2021 Sims AC, Mitchell HD, Gralinski LE, Kyle JE, Burnum-Johnson KE, Lam M, Fulcher ML, West A, Smith RD, Randell SH, Metz TO, Sheahan TP, Waters KM, Baric RS. Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury. Mbio. e0157221. PMID 34372702 DOI: 10.1128/mBio.01572-21  0.306
2021 Nakayasu ES, Gritsenko M, Piehowski PD, Gao Y, Orton DJ, Schepmoes AA, Fillmore TL, Frohnert BI, Rewers M, Krischer JP, Ansong C, Suchy-Dicey AM, Evans-Molina C, Qian WJ, Webb-Robertson BM, ... Metz TO, et al. Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation. Nature Protocols. PMID 34244696 DOI: 10.1038/s41596-021-00566-6  0.724
2021 Lee JY, Bilbao A, Conant CR, Bloodsworth KJ, Orton DJ, Zhou M, Wilson JW, Zheng X, Webb IK, Li A, Hixson KK, Fjeldsted JC, Ibrahim YM, Payne SH, Jansson C, ... ... Metz TO, et al. AutoCCS: Automated collision cross section calculation software for ion mobility spectrometry-mass spectrometry. Bioinformatics (Oxford, England). PMID 34145874 DOI: 10.1093/bioinformatics/btab429  0.329
2021 Kyle JE, Stratton KG, Zink EM, Kim YM, Bloodsworth KJ, Monroe ME, Waters KM, Webb-Robertson BM, Koeller DM, Metz TO. A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases. Scientific Data. 8: 114. PMID 33883556 DOI: 10.1038/s41597-021-00894-y  0.448
2020 Kim YM, Snijders AM, Brislawn CJ, Stratton KG, Zink EM, Fansler SJ, Metz TO, Mao JH, Jansson JK. Corrigendum: Light-Stress Influences the Composition of the Murine Gut Microbiome, Memory Function, and Plasma Metabolome. Frontiers in Molecular Biosciences. 7: 619718. PMID 33732731 DOI: 10.3389/fmolb.2020.619718  0.389
2020 Couvillion SP, Agrawal N, Colby SM, Brandvold KR, Metz TO. Who Is Metabolizing What? Discovering Novel Biomolecules in the Microbiome and the Organisms Who Make Them. Frontiers in Cellular and Infection Microbiology. 10: 388. PMID 32850487 DOI: 10.3389/Fcimb.2020.00388  0.323
2020 Leier HC, Weinstein JB, Kyle JE, Lee JY, Bramer LM, Stratton KG, Kempthorne D, Navratil AR, Tafesse EG, Hornemann T, Messer WB, Dennis EA, Metz TO, Barklis E, Tafesse FG. A global lipid map defines a network essential for Zika virus replication. Nature Communications. 11: 3652. PMID 32694525 DOI: 10.1038/S41467-020-17433-9  0.31
2020 McClure RS, Lee JY, Chowdhury TR, Bottos EM, White RA, Kim YM, Nicora CD, Metz TO, Hofmockel KS, Jansson JK, Song HS. Integrated network modeling approach defines key metabolic responses of soil microbiomes to perturbations. Scientific Reports. 10: 10882. PMID 32616808 DOI: 10.1038/S41598-020-67878-7  0.489
2020 Mao JH, Kim YM, Zhou YX, Hu D, Zhong C, Chang H, Brislawn CJ, Fansler S, Langley S, Wang Y, Peisl BYL, Celniker SE, Threadgill DW, Wilmes P, Orr G, ... Metz TO, et al. Correction to: Genetic and metabolic links between the murine microbiome and memory. Microbiome. 8: 73. PMID 32466793 DOI: 10.1186/S40168-020-00870-5  0.472
2020 Mao JH, Kim YM, Zhou YX, Hu D, Zhong C, Chang H, Brislawn C, Langley S, Wang Y, Peisl BYL, Celniker SE, Threadgill DW, Wilmes P, Orr G, Metz TO, et al. Genetic and metabolic links between the murine microbiome and memory. Microbiome. 8: 53. PMID 32299497 DOI: 10.1186/S40168-020-00817-W  0.488
2020 Ilhan ZE, DiBaise JK, Dautel SE, Isern NG, Kim YM, Hoyt DW, Schepmoes AA, Brewer HM, Weitz KK, Metz TO, Crowell MD, Kang DW, Rittmann BE, Krajmalnik-Brown R. Temporospatial shifts in the human gut microbiome and metabolome after gastric bypass surgery. Npj Biofilms and Microbiomes. 6: 12. PMID 32170068 DOI: 10.1038/s41522-020-0122-5  0.427
2020 Nakayasu ES, Syed F, Tersey SA, Gritsenko MA, Mitchell HD, Chan CY, Dirice E, Turatsinze JV, Cui Y, Kulkarni RN, Eizirik DL, Qian WJ, Webb-Robertson BM, Evans-Molina C, Mirmira RG, ... Metz TO, et al. Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metabolism. PMID 31928885 DOI: 10.1016/J.Cmet.2019.12.005  0.318
2020 Nicora CD, Sims AC, Bloodsworth KJ, Kim YM, Moore RJ, Kyle JE, Nakayasu ES, Metz TO. Metabolite, Protein, and Lipid Extraction (MPLEx): A Method that Simultaneously Inactivates Middle East Respiratory Syndrome Coronavirus and Allows Analysis of Multiple Host Cell Components Following Infection. Methods in Molecular Biology (Clifton, N.J.). 2099: 173-194. PMID 31883096 DOI: 10.1007/978-1-0716-0211-9_14  0.591
2019 Burnum-Johnson KE, Zheng X, Dodds JN, Ash J, Fourches D, Nicora CD, Wendler JP, Metz TO, Waters KM, Jansson JK, Smith RD, Baker ES. Ion Mobility Spectrometry and the Omics: Distinguishing Isomers, Molecular Classes and Contaminant Ions in Complex Samples. Trends in Analytical Chemistry : Trac. 116: 292-299. PMID 31798197 DOI: 10.1016/J.Trac.2019.04.022  0.624
2019 Webb-Robertson BM, Stratton KG, Kyle JE, Kim YM, Bramer LM, Waters KM, Koeller D, Metz TO. Statistically-driven Metabolite and Lipid Profiling of Patients from the Undiagnosed Diseases Network. Analytical Chemistry. PMID 31742994 DOI: 10.1021/Acs.Analchem.9B03522  0.526
2019 Kim YM, Snijders AM, Brislawn CJ, Stratton KG, Zink EM, Fansler SJ, Metz TO, Mao JH, Jansson JK. Light-Stress Influences the Composition of the Murine Gut Microbiome, Memory Function, and Plasma Metabolome. Frontiers in Molecular Biosciences. 6: 108. PMID 31681796 DOI: 10.3389/Fmolb.2019.00108  0.489
2019 Wojcik R, Nagy G, Attah IK, Webb I, Garimella SVB, Weitz KK, Hollerbach A, Monroe ME, Ligare MR, Nielson FF, Norheim RV, Renslow RS, Metz TO, Ibrahim YM, Smith RD. SLIM Ultrahigh Resolution Ion Mobility Spectrometry Separations of Isotopologues and Isotopomers Reveal Mobility Shifts due to Mass Distribution Changes. Analytical Chemistry. PMID 31450886 DOI: 10.1021/Acs.Analchem.9B02808  0.395
2019 Nuñez JR, Colby SM, Thomas DG, Tfaily MM, Tolic N, Ulrich EM, Sobus JR, Metz TO, Teeguarden JG, Renslow RS. Evaluation of Multifeature Libraries for Providing Evidence for the Presence of Small Molecules in Synthetic Blinded Samples. Journal of Chemical Information and Modeling. PMID 31430141 DOI: 10.1021/Acs.Jcim.9B00444  0.302
2019 Roy Chowdhury T, Lee JY, Bottos EM, Brislawn CJ, White RA, Bramer LM, Brown J, Zucker JD, Kim YM, Jumpponen A, Rice CW, Fansler SJ, Metz TO, McCue LA, Callister SJ, et al. Metaphenomic Responses of a Native Prairie Soil Microbiome to Moisture Perturbations. Msystems. 4. PMID 31186334 DOI: 10.1128/mSystems.00061-19  0.42
2019 Sharon G, Cruz NJ, Kang DW, Gandal MJ, Wang B, Kim YM, Zink EM, Casey CP, Taylor BC, Lane CJ, Bramer LM, Isern NG, Hoyt DW, Noecker C, Sweredoski MJ, ... ... Metz TO, et al. Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice. Cell. 177: 1600-1618.e17. PMID 31150625 DOI: 10.1016/J.Cell.2019.05.004  0.478
2019 Kyle JE, Burnum-Johnson KE, Wendler JP, Eisfeld AJ, Halfmann PJ, Watanabe T, Sahr F, Smith RD, Kawaoka Y, Waters KM, Metz TO. Plasma lipidome reveals critical illness and recovery from human Ebola virus disease. Proceedings of the National Academy of Sciences of the United States of America. 116: 3919-3928. PMID 30808769 DOI: 10.1073/Pnas.1815356116  0.38
2019 Bramer LM, Stratton KG, White AM, Bleeker AH, Kobold MA, Waters KM, Metz TO, Rodland KD, Webb-Robertson BM. P-Mart - Interactive Analysis of Ion Abundance Global Proteomics Data. Journal of Proteome Research. PMID 30667224 DOI: 10.1021/Acs.Jproteome.8B00840  0.338
2018 Gibbons BC, Fillmore TL, Gao Y, Liu T, Nakayasu ES, Moore RJ, Metz TO, Payne SH. Rapidly Assessing the Quality of Targeted Proteomics Experiments Through Monitoring Stable-isotope Labeled Standards. Journal of Proteome Research. PMID 30525668 DOI: 10.1021/Acs.Jproteome.8B00688  0.341
2018 Couvillion SP, Zhu Y, Nagy G, Adkins JN, Ansong C, Renslow RS, Piehowski PD, Ibrahim YM, Kelly RT, Metz TO. New mass spectrometry technologies contributing towards comprehensive and high throughput omics analyses of single cells. The Analyst. PMID 30507980 DOI: 10.1039/C8An01574K  0.651
2018 Nicora CD, Burnum-Johnson KE, Nakayasu ES, Casey CP, White RA, Roy Chowdhury T, Kyle JE, Kim YM, Smith RD, Metz TO, Jansson JK, Baker ES. The MPLEx Protocol for Multi-omic Analyses of Soil Samples. Journal of Visualized Experiments : Jove. PMID 29912205 DOI: 10.3791/57343  0.679
2018 Cole JK, Morton BR, Cardamone HC, Lake HRR, Dohnalkova AC, Kim YM, Kyle JE, Maezato Y, Dana KL, Metz TO, Romine MF, Nelson WC, Lindemann SR. Corrigendum: Saliniramus fredricksonii gen. nov., sp. nov., a heterotrophic halophile isolated from Hot Lake, Washington, a member of a novel lineage (Salinarimonadaceae fam. nov.) within the order Rhizobiales, and reclassification of the genus Salinarimonas Liu et al. 2010 into Salinarimonadaceae. International Journal of Systematic and Evolutionary Microbiology. 68: 2116-2123. PMID 29855404 DOI: 10.1099/Ijsem.0.002807  0.464
2018 Stanfill BA, Nakayasu ES, Bramer LM, Thompson AM, Ansong CK, Clauss T, Gritsenko MA, Monroe ME, Moore RJ, Orton DJ, Piehowski PD, Schepmoes AA, Smith RD, Webb-Robertson BJ, Metz TO, et al. QC-ART: A tool for real-time quality control assessment of mass spectrometry-based proteomics data. Molecular & Cellular Proteomics : McP. PMID 29666158 DOI: 10.1074/Mcp.Ra118.000648  0.663
2018 Cole JK, Morton BR, Cardamone HC, Lake HRR, Dohnalkova AC, Kim YM, Kyle JE, Maezato Y, Dana KL, Metz TO, Romine MF, Nelson WC, Lindemann SR. Salinivirga fredricksonii gen. nov., sp. nov., a heterotrophic halophile isolated from a photosynthetic mat, a member of a novel lineage (Salinarimonadaceae fam. nov.) within the order Rhizobiales, and reclassification of the genus Salinarimonas Liu et al. 2010 into Salinarimonadaceae. International Journal of Systematic and Evolutionary Microbiology. PMID 29580321 DOI: 10.1099/Ijsem.0.002715  0.462
2018 Moghieb A, Clair G, Mitchell H, Kitzmiller JA, Zink EM, Kim YM, Petyuk V, Shukla AK, Moore RJ, Metz TO, Carson JP, McDermott JE, Corley RA, Whitsett JA, Ansong C. Time-resolved Proteome Profiling of Normal Lung Development. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29516783 DOI: 10.1152/Ajplung.00316.2017  0.498
2018 Wu J, Sabag-Daigle A, Borton MA, Kop LFM, Szkoda BE, Deatherage Kaiser BL, Lindemann SR, Renslow RS, Wei S, Nicora CD, Weitz KK, Kim YM, Adkins JN, Metz TO, Boyaka P, et al. -mediated inflammation eliminates competitors for fructose-asparagine in the gut. Infection and Immunity. PMID 29483291 DOI: 10.1128/Iai.00945-17  0.463
2018 Oláhová M, Yoon WH, Thompson K, Jangam S, Fernandez L, Davidson JM, Kyle JE, Grove ME, Fisk DG, Kohler JN, Holmes M, Dries AM, Huang Y, Zhao C, Contrepois K, ... ... Metz TO, et al. Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder. American Journal of Human Genetics. PMID 29478781 DOI: 10.1016/J.Ajhg.2018.01.020  0.47
2018 Menachery VD, Schäfer A, Burnum-Johnson KE, Mitchell HD, Eisfeld AJ, Walters KB, Nicora CD, Purvine SO, Casey CP, Monroe ME, Weitz KK, Stratton KG, Webb-Robertson BM, Gralinski LE, Metz TO, et al. MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339515 DOI: 10.1073/Pnas.1706928115  0.374
2018 RoyChowdhury T, Bramer L, Hoyt DW, Kim Y, Metz TO, McCue LA, Diefenderfer HL, Jansson JK, Bailey V. Temporal dynamics of CO2 and CH4 loss potentials in response to rapid hydrological shifts in tidal freshwater wetland soils Ecological Engineering. 114: 104-114. DOI: 10.1016/J.Ecoleng.2017.06.041  0.486
2017 Eisfeld AJ, Halfmann PJ, Wendler JP, Kyle JE, Burnum-Johnson KE, Peralta Z, Maemura T, Walters KB, Watanabe T, Fukuyama S, Yamashita M, Jacobs JM, Kim YM, Casey CP, Stratton KG, ... ... Metz TO, et al. Multi-platform 'Omics Analysis of Human Ebola Virus Disease Pathogenesis. Cell Host & Microbe. PMID 29154144 DOI: 10.1016/J.Chom.2017.10.011  0.568
2017 Kerkhoven EJ, Kim YM, Wei S, Nicora CD, Fillmore TL, Purvine SO, Webb-Robertson BJ, Smith RD, Baker SE, Metz TO, Nielsen J. Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in Yarrowia lipolytica. Mbio. 8. PMID 28634240 DOI: 10.1128/Mbio.00857-17  0.574
2017 Ma J, Casey CP, Zheng X, Ibrahim YM, Wilkins CS, Renslow RS, Thomas DG, Payne SH, Monroe ME, Smith RD, Teeguarden JG, Baker ES, Metz TO. PIXiE: An Algorithm for Automated Ion Mobility Arrival Time Extraction and Collision Cross Section Calculation using Global Data Association. Bioinformatics (Oxford, England). PMID 28505286 DOI: 10.1093/Bioinformatics/Btx305  0.578
2017 Burnum-Johnson KE, Baker ES, Metz TO. Characterizing the lipid and metabolite changes associated with placental function and pregnancy complications using ion mobility spectrometry-mass spectrometry and mass spectrometry imaging. Placenta. PMID 28392013 DOI: 10.1016/J.Placenta.2017.03.016  0.555
2017 Kyle JE, Crowell KL, Casey CP, Fujimoto GM, Kim S, Dautel SE, Smith RD, Payne SH, Metz TO. LIQUID: an-open source software for identifying lipids in LC-MS/MS-based lipidomics data. Bioinformatics (Oxford, England). PMID 28158427 DOI: 10.1093/Bioinformatics/Btx046  0.438
2017 Dautel SE, Kyle JE, Clair G, Sontag RL, Weitz KK, Shukla AK, Nguyen SN, Kim YM, Zink EM, Luders T, Frevert CW, Gharib SA, Laskin J, Carson JP, Metz TO, et al. Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lung. Scientific Reports. 7: 40555. PMID 28145528 DOI: 10.1038/Srep40555  0.51
2017 Romine MF, Rodionov DA, Maezato Y, Anderson LN, Nandhikonda P, Rodionova IA, Carre A, Li X, Xu C, Clauss TR, Kim YM, Metz TO, Wright AT. Elucidation of roles for vitamin B12 in regulation of folate, ubiquinone, and methionine metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137868 DOI: 10.1073/Pnas.1612360114  0.487
2017 Burnum-Johnson KE, Kyle JE, Eisfeld AJ, Casey CP, Stratton KG, Gonzalez JF, Habyarimana F, Negretti NM, Sims AC, Chauhan S, Thackray LB, Halfmann PJ, Walters KB, Kim YM, Zink EM, ... ... Metz TO, et al. MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling. The Analyst. PMID 28091625 DOI: 10.1039/C6An02486F  0.598
2017 Metz TO, Baker ES, Schymanski EL, Renslow RS, Thomas DG, Causon TJ, Webb IK, Hann S, Smith RD, Teeguarden JG. Integrating ion mobility spectrometry into mass spectrometry-based exposome measurements: what can it add and how far can it go? Bioanalysis. 9: 81-98. PMID 27921453 DOI: 10.4155/Bio-2016-0244  0.628
2016 Zhang X, Romm M, Zheng X, Zink EM, Kim YM, Burnum-Johnson KE, Orton DJ, Apffel A, Ibrahim YM, Monroe ME, Moore RJ, Smith JN, Ma J, Renslow RS, Thomas DG, ... ... Metz TO, et al. SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids. Clinical Mass Spectrometry (Del Mar, Calif.). 2: 1-10. PMID 29276770 DOI: 10.1016/J.Clinms.2016.11.002  0.709
2016 Snijders AM, Langley SA, Kim YM, Brislawn CJ, Noecker C, Zink EM, Fansler SJ, Casey CP, Miller DR, Huang Y, Karpen GH, Celniker SE, Brown JB, Borenstein E, Jansson JK, ... Metz TO, et al. Influence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome. Nature Microbiology. 2: 16221. PMID 27892936 DOI: 10.1038/Nmicrobiol.2016.221  0.523
2016 Nakayasu ES, Nicora CD, Sims AC, Burnum-Johnson KE, Kim YM, Kyle JE, Matzke MM, Shukla AK, Chu RK, Schepmoes AA, Jacobs JM, Baric RS, Webb-Robertson BJ, Smith RD, Metz TO. MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses. Msystems. 1. PMID 27822525 DOI: 10.1128/mSystems.00043-16  0.566
2016 Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, ... ... Metz TO, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/Nbt.3597  0.327
2016 Pomraning KR, Kim YM, Nicora CD, Chu RK, Bredeweg EL, Purvine SO, Hu D, Metz TO, Baker SE. Multi-omics analysis reveals regulators of the response to nitrogen limitation in Yarrowia lipolytica. Bmc Genomics. 17: 138. PMID 26911370 DOI: 10.1186/S12864-016-2471-2  0.527
2016 Tisoncik-Go J, Gasper DJ, Kyle JE, Eisfeld AJ, Selinger C, Hatta M, Morrison J, Korth MJ, Zink EM, Kim YM, Schepmoes AA, Nicora CD, Purvine SO, Weitz KK, Peng X, ... ... Metz TO, et al. Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism. Cell Host & Microbe. 19: 254-66. PMID 26867183 DOI: 10.1016/J.Chom.2016.01.002  0.569
2016 Kyle JE, Zhang X, Weitz KK, Monroe ME, Ibrahim YM, Moore RJ, Cha J, Sun X, Lovelace ES, Wagoner J, Polyak SJ, Metz TO, Dey SK, Smith RD, Burnum-Johnson KE, et al. Uncovering biologically significant lipid isomers with liquid chromatography, ion mobility spectrometry and mass spectrometry. The Analyst. PMID 26734689 DOI: 10.1039/C5An02062J  0.645
2016 Metz TO. Mass spectrometry-based metabolomics: State-of-the-art and the future Placenta. 45: 69. DOI: 10.1016/J.Placenta.2016.06.033  0.308
2015 Lovelace ES, Wagoner J, MacDonald J, Bammler T, Bruckner J, Brownell J, Beyer RP, Zink EM, Kim YM, Kyle JE, Webb-Robertson BJ, Waters KM, Metz TO, Farin F, Oberlies NH, et al. Silymarin Suppresses Cellular Inflammation By Inducing Reparative Stress Signaling. Journal of Natural Products. 78: 1990-2000. PMID 26186142 DOI: 10.1021/acs.jnatprod.5b00288  0.498
2015 Suh MJ, Tovchigrechko A, Thovarai V, Rolfe MA, Torralba MG, Wang J, Adkins JN, Webb-Robertson BJ, Osborne W, Cogen FR, Kaplowitz PB, Metz TO, Nelson KE, Madupu R, Pieper R. Quantitative Differences in the Urinary Proteome of Siblings Discordant for Type 1 Diabetes Include Lysosomal Enzymes. Journal of Proteome Research. 14: 3123-35. PMID 26143644 DOI: 10.1021/Acs.Jproteome.5B00052  0.335
2015 Kebaabetswe LP, Haick AK, Gritsenko MA, Fillmore TL, Chu RK, Purvine SO, Webb-Robertson BJ, Matzke MM, Smith RD, Waters KM, Metz TO, Miura TA. Proteomic analysis reveals down-regulation of surfactant protein B in murine type II pneumocytes infected with influenza A virus. Virology. 483: 96-107. PMID 25965799 DOI: 10.1016/J.Virol.2015.03.045  0.424
2015 Kim YM, Nowack S, Olsen MT, Becraft ED, Wood JM, Thiel V, Klapper I, Kühl M, Fredrickson JK, Bryant DA, Ward DM, Metz TO. Diel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms. Frontiers in Microbiology. 6: 209. PMID 25941514 DOI: 10.3389/Fmicb.2015.00209  0.52
2015 Pomraning KR, Wei S, Karagiosis SA, Kim YM, Dohnalkova AC, Arey BW, Bredeweg EL, Orr G, Metz TO, Baker SE. Comprehensive Metabolomic, Lipidomic and Microscopic Profiling of Yarrowia lipolytica during Lipid Accumulation Identifies Targets for Increased Lipogenesis. Plos One. 10: e0123188. PMID 25905710 DOI: 10.1371/Journal.Pone.0123188  0.532
2015 Webb-Robertson BJ, Wiberg HK, Matzke MM, Brown JN, Wang J, McDermott JE, Smith RD, Rodland KD, Metz TO, Pounds JG, Waters KM. Review, evaluation, and discussion of the challenges of missing value imputation for mass spectrometry-based label-free global proteomics. Journal of Proteome Research. 14: 1993-2001. PMID 25855118 DOI: 10.1021/Pr501138H  0.452
2014 Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, ... ... Metz TO, et al. A comprehensive collection of systems biology data characterizing the host response to viral infection. Scientific Data. 1: 140033. PMID 25977790 DOI: 10.1038/Sdata.2014.33  0.614
2014 Webb-Robertson BJ, Matzke MM, Datta S, Payne SH, Kang J, Bramer LM, Nicora CD, Shukla AK, Metz TO, Rodland KD, Smith RD, Tardiff MF, McDermott JE, Pounds JG, Waters KM. Bayesian proteoform modeling improves protein quantification of global proteomic measurements. Molecular & Cellular Proteomics : McP. 13: 3639-46. PMID 25433089 DOI: 10.1074/Mcp.M113.030932  0.447
2014 Webb-Robertson BJ, Kim YM, Zink EM, Hallaian KA, Zhang Q, Madupu R, Waters KM, Metz TO. A Statistical Analysis of the Effects of Urease Pre-treatment on the Measurement of the Urinary Metabolome by Gas Chromatography-Mass Spectrometry. Metabolomics : Official Journal of the Metabolomic Society. 10: 897-908. PMID 25254001 DOI: 10.1007/S11306-014-0642-1  0.71
2014 Webb-Robertson BJ, Matzke MM, Datta S, Payne SH, Kang J, Bramer LM, Nicora CD, Shukla AK, Metz TO, Rodland KD, Smith RD, Tardiff MF, McDermott JE, Pounds JG, Waters KM. Bayesian Proteoform Modeling Improves Protein Quantification of Global Proteomic Measurements. Molecular & Cellular Proteomics : McP. PMID 25129695 DOI: 10.1074/mcp.O113.030932  0.36
2014 Huang EL, Aylward FO, Kim YM, Webb-Robertson BJ, Nicora CD, Hu Z, Metz TO, Lipton MS, Smith RD, Currie CR, Burnum-Johnson KE. The fungus gardens of leaf-cutter ants undergo a distinct physiological transition during biomass degradation. Environmental Microbiology Reports. 6: 389-95. PMID 24992538 DOI: 10.1111/1758-2229.12163  0.55
2014 Menachery VD, Eisfeld AJ, Schäfer A, Josset L, Sims AC, Proll S, Fan S, Li C, Neumann G, Tilton SC, Chang J, Gralinski LE, Long C, Green R, Williams CM, ... ... Metz TO, et al. Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses. Mbio. 5: e01174-14. PMID 24846384 DOI: 10.1128/Mbio.01174-14  0.385
2014 Cole JK, Hutchison JR, Renslow RS, Kim YM, Chrisler WB, Engelmann HE, Dohnalkova AC, Hu D, Metz TO, Fredrickson JK, Lindemann SR. Phototrophic biofilm assembly in microbial-mat-derived unicyanobacterial consortia: model systems for the study of autotroph-heterotroph interactions. Frontiers in Microbiology. 5: 109. PMID 24778628 DOI: 10.3389/Fmicb.2014.00109  0.499
2014 Anderson JC, Wan Y, Kim YM, Pasa-Tolic L, Metz TO, Peck SC. Decreased abundance of type III secretion system-inducing signals in Arabidopsis mkp1 enhances resistance against Pseudomonas syringae. Proceedings of the National Academy of Sciences of the United States of America. 111: 6846-51. PMID 24753604 DOI: 10.1073/Pnas.1403248111  0.642
2014 Merkley ED, Metz TO, Smith RD, Baynes JW, Frizzell N. The succinated proteome. Mass Spectrometry Reviews. 33: 98-109. PMID 24115015 DOI: 10.1002/Mas.21382  0.588
2013 Schmidt BJ, Ebrahim A, Metz TO, Adkins JN, Palsson BØ, Hyduke DR. GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data. Bioinformatics (Oxford, England). 29: 2900-8. PMID 23975765 DOI: 10.1093/Bioinformatics/Btt493  0.316
2013 Mitchell HD, Eisfeld AJ, Sims AC, McDermott JE, Matzke MM, Webb-Robertson BJ, Tilton SC, Tchitchek N, Josset L, Li C, Ellis AL, Chang JH, Heegel RA, Luna ML, Schepmoes AA, ... ... Metz TO, et al. A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses. Plos One. 8: e69374. PMID 23935999 DOI: 10.1371/Journal.Pone.0069374  0.394
2013 Gralinski LE, Bankhead A, Jeng S, Menachery VD, Proll S, Belisle SE, Matzke M, Webb-Robertson BJ, Luna ML, Shukla AK, Ferris MT, Bolles M, Chang J, Aicher L, Waters KM, ... ... Metz TO, et al. Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury. Mbio. 4. PMID 23919993 DOI: 10.1128/Mbio.00271-13  0.39
2013 Tchitchek N, Eisfeld AJ, Tisoncik-Go J, Josset L, Gralinski LE, Bécavin C, Tilton SC, Webb-Robertson BJ, Ferris MT, Totura AL, Li C, Neumann G, Metz TO, Smith RD, Waters KM, et al. Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice. Bmc Systems Biology. 7: 69. PMID 23895213 DOI: 10.1186/1752-0509-7-69  0.396
2013 Deatherage Kaiser BL, Li J, Sanford JA, Kim YM, Kronewitter SR, Jones MB, Peterson CT, Peterson SN, Frank BC, Purvine SO, Brown JN, Metz TO, Smith RD, Heffron F, Adkins JN. A Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection. Plos One. 8: e67155. PMID 23840608 DOI: 10.1371/Journal.Pone.0067155  0.564
2013 Kim YM, Schmidt BJ, Kidwai AS, Jones MB, Deatherage Kaiser BL, Brewer HM, Mitchell HD, Palsson BO, McDermott JE, Heffron F, Smith RD, Peterson SN, Ansong C, Hyduke DR, Metz TO, et al. Salmonella modulates metabolism during growth under conditions that induce expression of virulence genes. Molecular Biosystems. 9: 1522-34. PMID 23559334 DOI: 10.1039/C3Mb25598K  0.578
2013 LaMarche BL, Crowell KL, Jaitly N, Petyuk VA, Shah AR, Polpitiya AD, Sandoval JD, Kiebel GR, Monroe ME, Callister SJ, Metz TO, Anderson GA, Smith RD. MultiAlign: a multiple LC-MS analysis tool for targeted omics analysis. Bmc Bioinformatics. 14: 49. PMID 23398735 DOI: 10.1186/1471-2105-14-49  0.464
2013 Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR, Burkett SE, Zornetzer G, Tseng CT, ... Metz TO, et al. Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. Journal of Virology. 87: 3885-902. PMID 23365422 DOI: 10.1128/Jvi.02520-12  0.405
2013 Zhang Q, Fillmore TL, Schepmoes AA, Clauss TR, Gritsenko MA, Mueller PW, Rewers M, Atkinson MA, Smith RD, Metz TO. Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. The Journal of Experimental Medicine. 210: 191-203. PMID 23277452 DOI: 10.1084/Jem.20111843  0.667
2013 Ansong C, Schrimpe-Rutledge AC, Mitchell HD, Chauhan S, Jones MB, Kim YM, McAteer K, Deatherage Kaiser BL, Dubois JL, Brewer HM, Frank BC, McDermott JE, Metz TO, Peterson SN, Smith RD, et al. A multi-omic systems approach to elucidating Yersinia virulence mechanisms. Molecular Biosystems. 9: 44-54. PMID 23147219 DOI: 10.1039/C2Mb25287B  0.579
2013 Matzke MM, Brown JN, Gritsenko MA, Metz TO, Pounds JG, Rodland KD, Shukla AK, Smith RD, Waters KM, McDermott JE, Webb-Robertson BJ. A comparative analysis of computational approaches to relative protein quantification using peptide peak intensities in label-free LC-MS proteomics experiments. Proteomics. 13: 493-503. PMID 23019139 DOI: 10.1002/Pmic.201200269  0.479
2013 Ansong C, Deatherage BL, Hyduke D, Schmidt B, McDermott JE, Jones MB, Chauhan S, Charusanti P, Kim YM, Nakayasu ES, Li J, Kidwai A, Niemann G, Brown RN, Metz TO, et al. Studying Salmonellae and Yersiniae host-pathogen interactions using integrated 'omics and modeling. Current Topics in Microbiology and Immunology. 363: 21-41. PMID 22886542 DOI: 10.1007/82_2012_247  0.519
2012 Ansong C, Deatherage BL, Hyduke D, Schmidt B, McDermott JE, Jones MB, Chauhan S, Charusanti P, Kim YM, Nakayasu ES, Li J, Kidwai A, Niemann G, Brown RN, Metz TO, et al. Studying Salmonellae and Yersiniae Host–Pathogen Interactions Using Integrated ‘Omics and Modeling Current Topics in Microbiology and Immunology. 363: 21-41. PMID 22886542 DOI: 10.1007/82-2012-247  0.407
2012 Bordbar A, Mo ML, Nakayasu ES, Schrimpe-Rutledge AC, Kim YM, Metz TO, Jones MB, Frank BC, Smith RD, Peterson SN, Hyduke DR, Adkins JN, Palsson BO. Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation. Molecular Systems Biology. 8: 558. PMID 22735334 DOI: 10.1038/Msb.2012.21  0.569
2012 Hu ZP, Kim YM, Sowa MB, Robinson RJ, Gao X, Metz TO, Morgan WF, Zhang Q. Metabolomic response of human skin tissue to low dose ionizing radiation. Molecular Biosystems. 8: 1979-86. PMID 22610363 DOI: 10.1039/C2Mb25061F  0.667
2012 Kangas LJ, Metz TO, Isaac G, Schrom BT, Ginovska-Pangovska B, Wang L, Tan L, Lewis RR, Miller JH. In silico identification software (ISIS): a machine learning approach to tandem mass spectral identification of lipids. Bioinformatics (Oxford, England). 28: 1705-13. PMID 22592377 DOI: 10.1093/Bioinformatics/Bts194  0.33
2012 Schrimpe-Rutledge AC, Fontès G, Gritsenko MA, Norbeck AD, Anderson DJ, Waters KM, Adkins JN, Smith RD, Poitout V, Metz TO. Discovery of novel glucose-regulated proteins in isolated human pancreatic islets using LC-MS/MS-based proteomics. Journal of Proteome Research. 11: 3520-32. PMID 22578083 DOI: 10.1021/Pr3002996  0.419
2012 Perera R, Riley C, Isaac G, Hopf-Jannasch AS, Moore RJ, Weitz KW, Pasa-Tolic L, Metz TO, Adamec J, Kuhn RJ. Dengue virus infection perturbs lipid homeostasis in infected mosquito cells. Plos Pathogens. 8: e1002584. PMID 22457619 DOI: 10.1371/Journal.Ppat.1002584  0.557
2012 Nagai R, Murray DB, Metz TO, Baynes JW. Chelation: a fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications. Diabetes. 61: 549-59. PMID 22354928 DOI: 10.2337/Db11-1120  0.526
2012 Gao X, Zhang Q, Meng D, Isaac G, Zhao R, Fillmore TL, Chu RK, Zhou J, Tang K, Hu Z, Moore RJ, Smith RD, Katze MG, Metz TO. A reversed-phase capillary ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method for comprehensive top-down/bottom-up lipid profiling. Analytical and Bioanalytical Chemistry. 402: 2923-33. PMID 22354571 DOI: 10.1007/S00216-012-5773-5  0.665
2012 Menachery V, Sims A, Eisfeld A, Gralinski L, Chang J, Waters K, Metz T, Kawaoka Y, Katze M, Baric R. P115 Pathogenic Influenza A viruses and SARS-Coronaviruses modulate global interferon stimulated gene induction through diverse mechanisms Cytokine. 59: 556. DOI: 10.1016/J.Cyto.2012.06.206  0.304
2011 Shvartsburg AA, Isaac G, Leveque N, Smith RD, Metz TO. Separation and classification of lipids using differential ion mobility spectrometry. Journal of the American Society For Mass Spectrometry. 22: 1146-55. PMID 21953096 DOI: 10.1007/S13361-011-0114-Z  0.44
2011 Rasmussen AL, Diamond DL, McDermott JE, Gao X, Metz TO, Matzke MM, Carter VS, Belisle SE, Korth MJ, Waters KM, Smith RD, Katze MG. Systems virology identifies a mitochondrial fatty acid oxidation enzyme, dodecenoyl coenzyme A delta isomerase, required for hepatitis C virus replication and likely pathogenesis. Journal of Virology. 85: 11646-54. PMID 21917952 DOI: 10.1128/Jvi.05605-11  0.359
2011 Kim YM, Metz TO, Hu Z, Wiedner SD, Kim JS, Smith RD, Morgan WF, Zhang Q. Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics. Rapid Communications in Mass Spectrometry : Rcm. 25: 2561-4. PMID 21910289 DOI: 10.1002/Rcm.5134  0.7
2011 Matzke MM, Waters KM, Metz TO, Jacobs JM, Sims AC, Baric RS, Pounds JG, Webb-Robertson BJ. Improved quality control processing of peptide-centric LC-MS proteomics data. Bioinformatics (Oxford, England). 27: 2866-72. PMID 21852304 DOI: 10.1093/Bioinformatics/Btr479  0.358
2011 McDermott JE, Yoon H, Nakayasu ES, Metz TO, Hyduke DR, Kidwai AS, Palsson BO, Adkins JN, Heffron F. Technologies and approaches to elucidate and model the virulence program of salmonella. Frontiers in Microbiology. 2: 121. PMID 21687430 DOI: 10.3389/Fmicb.2011.00121  0.307
2011 Zhang Q, Monroe ME, Schepmoes AA, Clauss TR, Gritsenko MA, Meng D, Petyuk VA, Smith RD, Metz TO. Comprehensive identification of glycated peptides and their glycation motifs in plasma and erythrocytes of control and diabetic subjects. Journal of Proteome Research. 10: 3076-88. PMID 21612289 DOI: 10.1021/Pr200040J  0.657
2011 Gonzalez RM, Zhang Q, Zangar RC, Smith RD, Metz TO. Development of a fibrinogen-specific sandwich enzyme-linked immunosorbent assay microarray assay for distinguishing between blood plasma and serum samples. Analytical Biochemistry. 414: 99-102. PMID 21371419 DOI: 10.1016/J.Ab.2011.02.039  0.616
2011 Shvartsburg AA, Isaac G, Leveque N, Smith RD, Metz TO. Erratum to: Separation and Classification of Lipids Using Differential Ion Mobility Spectrometry Journal of the American Society For Mass Spectrometry. 22: 1156-1156. DOI: 10.1007/S13361-011-0156-2  0.381
2010 Webb-Robertson BJ, McCue LA, Waters KM, Matzke MM, Jacobs JM, Metz TO, Varnum SM, Pounds JG. Combined statistical analyses of peptide intensities and peptide occurrences improves identification of significant peptides from MS-based proteomics data. Journal of Proteome Research. 9: 5748-56. PMID 20831241 DOI: 10.1021/Pr1005247  0.356
2010 Sorensen CM, Ding J, Zhang Q, Alquier T, Zhao R, Mueller PW, Smith RD, Metz TO. Perturbations in the lipid profile of individuals with newly diagnosed type 1 diabetes mellitus: lipidomics analysis of a Diabetes Antibody Standardization Program sample subset. Clinical Biochemistry. 43: 948-56. PMID 20519132 DOI: 10.1016/J.Clinbiochem.2010.04.075  0.655
2010 Diamond DL, Syder AJ, Jacobs JM, Sorensen CM, Walters KA, Proll SC, McDermott JE, Gritsenko MA, Zhang Q, Zhao R, Metz TO, Camp DG, Waters KM, Smith RD, Rice CM, et al. Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics. Plos Pathogens. 6: e1000719. PMID 20062526 DOI: 10.1371/Journal.Ppat.1000719  0.636
2010 Adkins JN, Mottaz H, Metz TO, Ansong C, Manes NP, Smith RD, Heffron F. Performing comparative peptidomics analyses of Salmonella from different growth conditions. Methods in Molecular Biology (Clifton, N.J.). 615: 13-27. PMID 20013197 DOI: 10.1007/978-1-60761-535-4_2  0.463
2009 Alquier T, Peyot ML, Latour MG, Kebede M, Sorensen CM, Gesta S, Ronald Kahn C, Smith RD, Jetton TL, Metz TO, Prentki M, Poitout V. Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets. Diabetes. 58: 2607-15. PMID 19720802 DOI: 10.2337/Db09-0362  0.365
2009 Karpievitch Y, Stanley J, Taverner T, Huang J, Adkins JN, Ansong C, Heffron F, Metz TO, Qian WJ, Yoon H, Smith RD, Dabney AR. A statistical framework for protein quantitation in bottom-up MS-based proteomics. Bioinformatics (Oxford, England). 25: 2028-34. PMID 19535538 DOI: 10.1093/Bioinformatics/Btp362  0.448
2009 Zhang Q, Ames JM, Smith RD, Baynes JW, Metz TO. A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: probing the pathogenesis of chronic disease. Journal of Proteome Research. 8: 754-69. PMID 19093874 DOI: 10.1021/Pr800858H  0.729
2009 Zhang Q, Ames JM, Smith RD, Baynes JW, Metz TO. A perspective on the maillard reaction and the analysis of protein glycation by mass spectrometry Journal of Proteome Research. 8: 754-769. DOI: 10.1021/Pr80085Bh  0.72
2008 Metz TO, Page JS, Baker ES, Tang K, Ding J, Shen Y, Smith RD. High Resolution Separations and Improved Ion Production and Transmission in Metabolomics. Trends in Analytical Chemistry : Trac. 27: 205-214. PMID 19255623 DOI: 10.1016/J.Trac.2007.11.003  0.628
2008 Zhang Q, Schepmoes AA, Brock JW, Wu S, Moore RJ, Purvine SO, Baynes JW, Smith RD, Metz TO. Improved methods for the enrichment and analysis of glycated peptides. Analytical Chemistry. 80: 9822-9. PMID 18989935 DOI: 10.1021/Ac801704J  0.775
2008 Zhang Q, Petyuk VA, Schepmoes AA, Orton DJ, Monroe ME, Yang F, Smith RD, Metz TO. Analysis of non-enzymatically glycated peptides: neutral-loss-triggered MS(3) versus multi-stage activation tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 22: 3027-34. PMID 18763275 DOI: 10.1002/Rcm.3703  0.668
2008 Ding J, Sorensen CM, Jaitly N, Jiang H, Orton DJ, Monroe ME, Moore RJ, Smith RD, Metz TO. Application of the accurate mass and time tag approach in studies of the human blood lipidome. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 871: 243-52. PMID 18502191 DOI: 10.1016/J.Jchromb.2008.04.040  0.458
2008 Zhang Q, Tang N, Schepmoes AA, Phillips LS, Smith RD, Metz TO. Proteomic profiling of nonenzymatically glycated proteins in human plasma and erythrocyte membranes. Journal of Proteome Research. 7: 2025-32. PMID 18396901 DOI: 10.1021/Pr700763R  0.659
2008 Petyuk VA, Jaitly N, Moore RJ, Ding J, Metz TO, Tang K, Monroe ME, Tolmachev AV, Adkins JN, Belov ME, Dabney AR, Qian WJ, Camp DG, Smith RD. Elimination of systematic mass measurement errors in liquid chromatography-mass spectrometry based proteomics using regression models and a priori partial knowledge of the sample content. Analytical Chemistry. 80: 693-706. PMID 18163597 DOI: 10.1021/Ac701863D  0.428
2008 Metz TO, Qian WJ, Jacobs JM, Gritsenko MA, Moore RJ, Polpitiya AD, Monroe ME, Camp DG, Mueller PW, Smith RD. Application of proteomics in the discovery of candidate protein biomarkers in a diabetes autoantibody standardization program sample subset. Journal of Proteome Research. 7: 698-707. PMID 18092746 DOI: 10.1021/Pr700606W  0.467
2007 Metz TO, Zhang Q, Page JS, Shen Y, Callister SJ, Jacobs JM, Smith RD. The future of liquid chromatography-mass spectrometry (LC-MS) in metabolic profiling and metabolomic studies for biomarker discovery. Biomarkers in Medicine. 1: 159-185. PMID 19177179 DOI: 10.2217/17520363.1.1.159  0.677
2007 Ding J, Sorensen CM, Zhang Q, Jiang H, Jaitly N, Livesay EA, Shen Y, Smith RD, Metz TO. Capillary LC coupled with high-mass measurement accuracy mass spectrometry for metabolic profiling. Analytical Chemistry. 79: 6081-93. PMID 17636878 DOI: 10.1021/Ac070080Q  0.67
2007 Zhang Q, Tang N, Brock JW, Mottaz HM, Ames JM, Baynes JW, Smith RD, Metz TO. Enrichment and analysis of nonenzymatically glycated peptides: boronate affinity chromatography coupled with electron-transfer dissociation mass spectrometry. Journal of Proteome Research. 6: 2323-30. PMID 17488106 DOI: 10.1021/Pr070112Q  0.776
2007 Zhang Q, Frolov A, Tang N, Hoffmann R, van de Goor T, Metz TO, Smith RD. Application of electron transfer dissociation mass spectrometry in analyses of non-enzymatically glycated peptides. Rapid Communications in Mass Spectrometry : Rcm. 21: 661-6. PMID 17279487 DOI: 10.1002/Rcm.2884  0.65
2007 Manes NP, Gustin JK, Rue J, Mottaz HM, Purvine SO, Norbeck AD, Monroe ME, Zimmer JS, Metz TO, Adkins JN, Smith RD, Heffron F. Targeted protein degradation by Salmonella under phagosome-mimicking culture conditions investigated using comparative peptidomics. Molecular & Cellular Proteomics : McP. 6: 717-27. PMID 17228056 DOI: 10.1074/Mcp.M600282-Mcp200  0.438
2006 Metz TO, Jacobs JM, Gritsenko MA, Fontès G, Qian WJ, Camp DG, Poitout V, Smith RD. Characterization of the human pancreatic islet proteome by two-dimensional LC/MS/MS. Journal of Proteome Research. 5: 3345-54. PMID 17137336 DOI: 10.1021/Pr060322N  0.463
2005 Shen Y, Strittmatter EF, Zhang R, Metz TO, Moore RJ, Li F, Udseth HR, Smith RD, Unger KK, Kumar D, Lubda D. Making broad proteome protein measurements in 1-5 min using high-speed RPLC separations and high-accuracy mass measurements. Analytical Chemistry. 77: 7763-73. PMID 16316187 DOI: 10.1021/Ac051257O  0.464
2005 Shen Y, Zhang R, Moore RJ, Kim J, Metz TO, Hixson KK, Zhao R, Livesay EA, Udseth HR, Smith RD. Automated 20 kpsi RPLC-MS and MS/MS with chromatographic peak capacities of 1000-1500 and capabilities in proteomics and metabolomics. Analytical Chemistry. 77: 3090-100. PMID 15889897 DOI: 10.1021/Ac0483062  0.489
2005 Stroman ML, Metz TO, Thorpe SR, Baynes JW. Cleavage of dicarbonyl compounds by the advanced glycation/lipoxidation end product inhibitor pyridoxamine Annals of the New York Academy of Sciences. 1043: 946. DOI: 10.1196/Annals.1333.160  0.493
2004 Cotham WE, Metz TO, Ferguson PL, Brock JW, Hinton DJ, Thorpe SR, Baynes JW, Ames JM. Proteomic analysis of arginine adducts on glyoxal-modified ribonuclease. Molecular & Cellular Proteomics : McP. 3: 1145-53. PMID 15377717 DOI: 10.1074/Mcp.M400002-Mcp200  0.666
2004 Alderson NL, Chachich ME, Frizzell N, Canning P, Metz TO, Januszewski AS, Youssef NN, Stitt AW, Baynes JW, Thorpe SR. Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat. Diabetologia. 47: 1385-95. PMID 15309289 DOI: 10.1007/S00125-004-1474-8  0.475
2003 Cotham WE, Hinton DJ, Metz TO, Brock JW, Thorpe SR, Baynes JW, Ames JM. Mass spectrometric analysis of glucose-modified ribonuclease. Biochemical Society Transactions. 31: 1426-7. PMID 14641080 DOI: 10.1042/Bst0311426  0.654
2003 Januszewski AS, Alderson NL, Metz TO, Thorpe SR, Baynes JW. Role of lipids in chemical modification of proteins and development of complications in diabetes. Biochemical Society Transactions. 31: 1413-6. PMID 14641077 DOI: 10.1042/Bst0311413  0.553
2003 Brock JW, Hinton DJ, Cotham WE, Metz TO, Thorpe SR, Baynes JW, Ames JM. Proteomic analysis of the site specificity of glycation and carboxymethylation of ribonuclease. Journal of Proteome Research. 2: 506-13. PMID 14582647 DOI: 10.1021/Pr0340173  0.655
2003 Metz TO, Alderson NL, Thorpe SR, Baynes JW. Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications. Archives of Biochemistry and Biophysics. 419: 41-9. PMID 14568007 DOI: 10.1016/J.Abb.2003.08.021  0.534
2003 Metz TO, Alderson NL, Chachich ME, Thorpe SR, Baynes JW. Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: evidence on the role of lipids in chemical modification of protein and development of diabetic complications. The Journal of Biological Chemistry. 278: 42012-9. PMID 12923193 DOI: 10.1074/Jbc.M304292200  0.552
2002 Voziyan PA, Metz TO, Baynes JW, Hudson BG. A post-Amadori inhibitor pyridoxamine also inhibits chemical modification of proteins by scavenging carbonyl intermediates of carbohydrate and lipid degradation. The Journal of Biological Chemistry. 277: 3397-403. PMID 11729198 DOI: 10.1074/Jbc.M109935200  0.554
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