| Year |
Citation |
Score |
| 2023 |
Vaziri-Gohar A, Hue JJ, Abbas A, Graor HJ, Hajihassani O, Zarei M, Titomihelakis G, Feczko J, Rathore M, Chelstowska S, Loftus AW, Wang R, Zarei M, Goudarzi M, Zhang R, ... ... Brunengraber H, et al. Increased glucose availability sensitizes pancreatic cancer to chemotherapy. Nature Communications. 14: 3823. PMID 37380658 DOI: 10.1038/s41467-023-38921-8 |
0.581 |
|
| 2022 |
Vaziri-Gohar A, Cassel J, Mohammed FS, Zarei M, Hue JJ, Hajihassani O, Graor HJ, Srikanth YVV, Karim SA, Abbas A, Prendergast E, Chen V, Katayama ES, Dukleska K, Khokhar I, ... ... Brunengraber H, et al. Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors. Nature Cancer. PMID 35681100 DOI: 10.1038/s43018-022-00393-y |
0.593 |
|
| 2021 |
Hala D, Petersen LH, Huggett DB, Puchowicz MA, Brunengraber H, Zhang GF. Overcompensation of CoA Trapping by Di(2-ethylhexyl) Phthalate (DEHP) Metabolites in Livers of Wistar Rats. International Journal of Molecular Sciences. 22. PMID 34948286 DOI: 10.3390/ijms222413489 |
0.315 |
|
| 2020 |
Singh C, Tran V, McCollum L, Bolok Y, Allan K, Yuan A, Hoppe G, Brunengraber H, Sears JE. Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells. Nature Communications. 11: 1277. PMID 32152301 DOI: 10.1038/S41467-020-15066-6 |
0.303 |
|
| 2019 |
Zhao Y, Zhao X, Chen V, Feng Y, Wang L, Croniger C, Conlon RA, Markowitz S, Fearon E, Puchowicz M, Brunengraber H, Hao Y, Wang Z. Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo. Scientific Reports. 9: 19180. PMID 31844152 DOI: 10.1038/S41598-019-55718-2 |
0.302 |
|
| 2019 |
Singh C, Hoppe G, Tran V, McCollum L, Bolok Y, Song W, Sharma A, Brunengraber H, Sears JE. Serine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity. Jci Insight. 4. PMID 31341109 DOI: 10.1172/Jci.Insight.129398 |
0.377 |
|
| 2018 |
Wang Y, Christopher BA, Wilson KA, Muoio D, McGarrah RW, Brunengraber H, Zhang GF. Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by L-carnitine. American Journal of Physiology. Endocrinology and Metabolism. PMID 30016154 DOI: 10.1152/Ajpendo.00081.2018 |
0.457 |
|
| 2017 |
Wilson KA, Han Y, Zhang M, Hess J, Chapman KA, Cline GW, Tochtrop GP, Brunengraber H, Zhang GF. Interrelations between 3-hydroxypropionate and propionate metabolism in rat liver: Relevance to disorders of propionyl-CoA metabolism. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00105.2017. PMID 28634175 DOI: 10.1152/Ajpendo.00105.2017 |
0.447 |
|
| 2016 |
Taegtmeyer H, Young ME, Lopaschuk GD, Abel ED, Brunengraber H, Darley-Usmar V, Des Rosiers C, Gerszten R, Glatz JF, Griffin JL, Gropler RJ, Holzhuetter HG, Kizer JR, Lewandowski ED, Malloy CR, et al. Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association. Circulation Research. 118: 1659-701. PMID 27012580 DOI: 10.1161/Res.0000000000000097 |
0.304 |
|
| 2015 |
Lin JB, Mast N, Bederman IR, Li Y, Brunengraber H, Björkhem I, Pikuleva IA. Cholesterol in mouse retina originates primarily from in situ de novo biosynthesis. Journal of Lipid Research. PMID 26630912 DOI: 10.1194/Jlr.M064469 |
0.621 |
|
| 2015 |
Jin Z, Bian F, Tomcik K, Kelleher JK, Zhang GF, Brunengraber H. Compartmentation of metabolism of the C12-, C9-, and C5-n-dicarboxylates in rat liver, investigated by mass isotopomer analysis: Anaplerosis from dodecanedioate. The Journal of Biological Chemistry. PMID 26070565 DOI: 10.1074/Jbc.M115.651737 |
0.509 |
|
| 2015 |
Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, et al. A roadmap for interpreting (13)C metabolite labeling patterns from cells. Current Opinion in Biotechnology. 34: 189-201. PMID 25731751 DOI: 10.1016/J.Copbio.2015.02.003 |
0.395 |
|
| 2015 |
Li Q, Deng S, Ibarra RA, Anderson VE, Brunengraber H, Zhang GF. Multiple mass isotopomer tracing of acetyl-CoA metabolism in Langendorff-perfused rat hearts: channeling of acetyl-CoA from pyruvate dehydrogenase to carnitine acetyltransferase. The Journal of Biological Chemistry. 290: 8121-32. PMID 25645937 DOI: 10.1074/Jbc.M114.631549 |
0.447 |
|
| 2014 |
Anand P, Hausladen A, Wang YJ, Zhang GF, Stomberski C, Brunengraber H, Hess DT, Stamler JS. Identification of S-nitroso-CoA reductases that regulate protein S-nitrosylation. Proceedings of the National Academy of Sciences of the United States of America. 111: 18572-7. PMID 25512491 DOI: 10.1073/Pnas.1417816112 |
0.305 |
|
| 2014 |
Dazard JE, Sandlers Y, Doerner SK, Berger NA, Brunengraber H. Metabolomics of ApcMin/+ mice genetically susceptible to intestinal cancer. Bmc Systems Biology. 8: 72. PMID 24954394 DOI: 10.1186/1752-0509-8-72 |
0.377 |
|
| 2014 |
Ibarra R, Dazard JE, Sandlers Y, Rehman F, Abbas R, Kombu R, Zhang GF, Brunengraber H, Sanabria J. Metabolomic Analysis of Liver Tissue from the VX2 Rabbit Model of Secondary Liver Tumors. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2014: 310372. PMID 24723740 DOI: 10.1155/2014/310372 |
0.401 |
|
| 2013 |
Guay C, Joly E, Pepin E, Barbeau A, Hentsch L, Pineda M, Madiraju SR, Brunengraber H, Prentki M. A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells. Plos One. 8: e77097. PMID 24130841 DOI: 10.1371/Journal.Pone.0077097 |
0.341 |
|
| 2013 |
Harris SR, Zhang GF, Sadhukhan S, Wang H, Shi C, Puchowicz MA, Anderson VE, Salomon RG, Tochtrop GP, Brunengraber H. Metabolomics and mass isotopomer analysis as a strategy for pathway discovery: pyrrolyl and cyclopentenyl derivatives of the pro-drug of abuse, levulinate. Chemical Research in Toxicology. 26: 213-20. PMID 23171137 DOI: 10.1021/Tx3003643 |
0.399 |
|
| 2012 |
Zhang GF, Sadhukhan S, Ibarra RA, Lauden SM, Chuang CY, Sushailo S, Chatterjee P, Anderson VE, Tochtrop GP, Brunengraber H. Metabolism of γ-hydroxybutyrate in perfused rat livers. The Biochemical Journal. 444: 333-41. PMID 22428548 DOI: 10.1042/Bj20112046 |
0.472 |
|
| 2012 |
Brunengraber H. What is the proper precursor-to-product labeling relationship for calculating the fractional synthetic rate of muscle triglyceride? Journal of Lipid Research. 53: 1-3. PMID 22075970 DOI: 10.1194/Jlr.E022426 |
0.469 |
|
| 2011 |
Andres Ibarra R, Abbas R, Kombu RS, Zhang GF, Jacobs G, Lee Z, Brunengraber H, Sanabria JR. Disturbances in the glutathione/ophthalmate redox buffer system in the woodchuck model of hepatitis virus-induced hepatocellular carcinoma. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2011: 789323. PMID 21941408 DOI: 10.1155/2011/789323 |
0.307 |
|
| 2011 |
Zhang GF, Sadhukhan S, Tochtrop GP, Brunengraber H. Metabolomics, pathway regulation, and pathway discovery. The Journal of Biological Chemistry. 286: 23631-5. PMID 21566142 DOI: 10.1074/Jbc.R110.171405 |
0.33 |
|
| 2011 |
Abbas R, Kombu RS, Ibarra RA, Goyal KK, Brunengraber H, Sanabria JR. The dynamics of glutathione species and ophthalmate concentrations in plasma from the VX2 rabbit model of secondary liver tumors. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2011: 709052. PMID 21350723 DOI: 10.1155/2011/709052 |
0.315 |
|
| 2011 |
Kombu RS, Brunengraber H, Puchowicz MA. Analysis of the citric acid cycle intermediates using gas chromatography-mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 708: 147-57. PMID 21207288 DOI: 10.1007/978-1-61737-985-7_8 |
0.406 |
|
| 2011 |
Harris SR, Zhang GF, Sadhukhan S, Murphy AM, Tomcik KA, Vazquez EJ, Anderson VE, Tochtrop GP, Brunengraber H. Metabolism of levulinate in perfused rat livers and live rats: conversion to the drug of abuse 4-hydroxypentanoate. The Journal of Biological Chemistry. 286: 5895-904. PMID 21126961 DOI: 10.1074/Jbc.M110.196808 |
0.427 |
|
| 2011 |
Li W, Bian F, Chaudhuri P, Mao X, Brunengraber H, Yu X. Delineation of substrate selection and anaplerosis in tricarboxylic acid cycle of the heart by 13C NMR spectroscopy and mass spectrometry. Nmr in Biomedicine. 24: 176-87. PMID 20960584 DOI: 10.1002/Nbm.1569 |
0.438 |
|
| 2011 |
Asgeri M, Waghray N, Mullen K, Nader N, Brunengraber H, Sanabria J. Partial IVC Clamping Improves Intraoperative Hemodynamic Parameters in the Rodent Portacaval Anastomosis Model Surgical Science. 2: 102-108. DOI: 10.4236/Ss.2011.22021 |
0.305 |
|
| 2010 |
Sadhukhan S, Han Y, Zhang GF, Brunengraber H, Tochtrop GP. Using isotopic tools to dissect and quantitate parallel metabolic pathways. Journal of the American Chemical Society. 132: 6309-11. PMID 20408520 DOI: 10.1021/Ja100399M |
0.37 |
|
| 2010 |
Gu L, Zhang GF, Kombu RS, Allen F, Kutz G, Brewer WU, Roe CR, Brunengraber H. Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. II. Effects on lipolysis, glucose production, and liver acyl-CoA profile. American Journal of Physiology. Endocrinology and Metabolism. 298: E362-71. PMID 19903863 DOI: 10.1152/Ajpendo.00384.2009 |
0.468 |
|
| 2010 |
Abbas R, Kombu RS, Dignam D, Gunning W, Stulberg JJ, Brunengraber H, Sanabria JR. Polyethylene glycol modified-albumin enhances the cold preservation properties of University of Wisconsin solution in rat liver and a hepatocyte cell line. The Journal of Surgical Research. 164: 95-104. PMID 19577257 DOI: 10.1016/J.Jss.2009.03.030 |
0.329 |
|
| 2009 |
Kasumov T, Sharma N, Huang H, Kombu RS, Cendrowski A, Stanley WC, Brunengraber H. Dipropionylcysteine ethyl ester compensates for loss of citric acid cycle intermediates during post ischemia reperfusion in the pig heart. Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 23: 459-69. PMID 19967553 DOI: 10.1007/S10557-009-6208-1 |
0.325 |
|
| 2009 |
Zhang GF, Kombu RS, Kasumov T, Han Y, Sadhukhan S, Zhang J, Sayre LM, Ray D, Gibson KM, Anderson VA, Tochtrop GP, Brunengraber H. Catabolism of 4-hydroxyacids and 4-hydroxynonenal via 4-hydroxy-4-phosphoacyl-CoAs. The Journal of Biological Chemistry. 284: 33521-34. PMID 19759021 DOI: 10.1074/Jbc.M109.055665 |
0.464 |
|
| 2009 |
Deng S, Zhang GF, Kasumov T, Roe CR, Brunengraber H. Interrelations between C4 ketogenesis, C5 ketogenesis, and anaplerosis in the perfused rat liver. The Journal of Biological Chemistry. 284: 27799-807. PMID 19666922 DOI: 10.1074/Jbc.M109.048744 |
0.447 |
|
| 2009 |
Previs SF, Brunengraber DZ, Brunengraber H. Is there glucose production outside of the liver and kidney? Annual Review of Nutrition. 29: 43-57. PMID 19575601 DOI: 10.1146/Annurev-Nutr-080508-141134 |
0.339 |
|
| 2009 |
Kombu RS, Zhang GF, Abbas R, Mieyal JJ, Anderson VE, Kelleher JK, Sanabria JR, Brunengraber H. Dynamics of glutathione and ophthalmate traced with 2H-enriched body water in rats and humans. American Journal of Physiology. Endocrinology and Metabolism. 297: E260-9. PMID 19401458 DOI: 10.1152/Ajpendo.00080.2009 |
0.387 |
|
| 2009 |
Sanabria J, Abbas R, Kombu S, Brunengraber H. QS312. Ophthalmic Acid and Glutathione Concentration in Secondary Liver Tumors Subsistence and Growth Journal of Surgical Research. 151: 296. DOI: 10.1016/J.Jss.2008.11.618 |
0.368 |
|
| 2008 |
Yang L, Kombu RS, Kasumov T, Zhu SH, Cendrowski AV, David F, Anderson VE, Kelleher JK, Brunengraber H. Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. I. Interrelation between gluconeogenesis and cataplerosis; formation of methoxamates from aminooxyacetate and ketoacids. The Journal of Biological Chemistry. 283: 21978-87. PMID 18544527 DOI: 10.1074/Jbc.M803454200 |
0.47 |
|
| 2008 |
Yang L, Kasumov T, Kombu RS, Zhu SH, Cendrowski AV, David F, Anderson VE, Kelleher JK, Brunengraber H. Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle: II. Heterogeneity of metabolite labeling pattern. The Journal of Biological Chemistry. 283: 21988-96. PMID 18544526 DOI: 10.1074/Jbc.M803455200 |
0.511 |
|
| 2008 |
Wang X, Stanley WC, Darrow CJ, Brunengraber H, Takhar Kasumov. Corrigendum to "Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry" [Anal. Biochem. 363 (2007) 169-174] (DOI:10.1016/j.ab.2007.01.010) Analytical Biochemistry. 375: 162. DOI: 10.1016/J.Ab.2007.12.018 |
0.309 |
|
| 2007 |
Kasumov T, Cendrowski AV, David F, Jobbins KA, Anderson VE, Brunengraber H. Mass isotopomer study of anaplerosis from propionate in the perfused rat heart. Archives of Biochemistry and Biophysics. 463: 110-7. PMID 17418801 DOI: 10.1016/J.Abb.2007.02.022 |
0.496 |
|
| 2007 |
Wang X, Stanley WC, Darrow CJ, Brunengraber H, Kasumov T. Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry. Analytical Biochemistry. 363: 169-74. PMID 17316539 DOI: 10.1016/J.Ab.2007.01.010 |
0.476 |
|
| 2007 |
Kovacs WJ, Tape KN, Shackelford JE, Duan X, Kasumov T, Kelleher JK, Brunengraber H, Krisans SK. Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes. Histochemistry and Cell Biology. 127: 273-90. PMID 17180682 DOI: 10.1007/S00418-006-0254-6 |
0.358 |
|
| 2007 |
Chuang C, Zhang G, Sushailo S, David F, Koshy J, Brunengraber H. Interference of ethanol with the metabolism of gamma‐hydroxybutyrate (GHB) in the perfused rat liver The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A664-C |
0.351 |
|
| 2007 |
Zhang G, Bian F, Kasumov T, Chuang C, Cendrowski AV, David F, Minkler PE, Hoppel CL, Anderson VA, Brunengraber H. Partial beta‐oxidation of gamma‐hydroxybutyrate (GHB) in perfused rat livers The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A664-A |
0.355 |
|
| 2006 |
Bian F, Kasumov T, Jobbins KA, Minkler PE, Anderson VE, Kerner J, Hoppel CL, Brunengraber H. Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart. Journal of Molecular and Cellular Cardiology. 41: 868-75. PMID 17020764 DOI: 10.1016/J.Yjmcc.2006.08.011 |
0.49 |
|
| 2006 |
Brunengraber H, Roe CR. Anaplerotic molecules: current and future. Journal of Inherited Metabolic Disease. 29: 327-31. PMID 16763895 DOI: 10.1007/S10545-006-0320-1 |
0.38 |
|
| 2006 |
Kinman RP, Kasumov T, Jobbins KA, Thomas KR, Adams JE, Brunengraber LN, Kutz G, Brewer WU, Roe CR, Brunengraber H. Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. American Journal of Physiology. Endocrinology and Metabolism. 291: E860-6. PMID 16705058 DOI: 10.1152/Ajpendo.00366.2005 |
0.44 |
|
| 2006 |
Okere IC, McElfresh TA, Brunengraber DZ, Martini W, Sterk JP, Huang H, Chandler MP, Brunengraber H, Stanley WC. Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion. Journal of Applied Physiology (Bethesda, Md. : 1985). 100: 76-82. PMID 16141384 DOI: 10.1152/Japplphysiol.00255.2005 |
0.33 |
|
| 2006 |
Yang L, Kasumov T, Yu L, Jobbins KA, David F, Previs SF, Kelleher JK, Brunengraber H. Metabolomic assays of the concentration and mass isotopomer distribution of gluconeogenic and citric acid cycle intermediates Metabolomics. 2: 85-94. DOI: 10.1007/S11306-006-0019-1 |
0.767 |
|
| 2006 |
Kasumov T, Brunengraber H. An improved procedure for the synthesis of labelled fatty acids utilizing diethyl malonate Journal of Labelled Compounds and Radiopharmaceuticals. 49: 171-176. DOI: 10.1002/Jlcr.1034 |
0.364 |
|
| 2005 |
Mochel F, DeLonlay P, Touati G, Brunengraber H, Kinman RP, Rabier D, Roe CR, Saudubray JM. Pyruvate carboxylase deficiency: clinical and biochemical response to anaplerotic diet therapy. Molecular Genetics and Metabolism. 84: 305-12. PMID 15781190 DOI: 10.1016/J.Ymgme.2004.09.007 |
0.392 |
|
| 2005 |
Kasumov T, Adams JE, Bian F, David F, Thomas KR, Jobbins KA, Minkler PE, Hoppel CL, Brunengraber H. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. The Biochemical Journal. 389: 397-401. PMID 15773815 DOI: 10.1042/Bj20050144 |
0.45 |
|
| 2005 |
Bian F, Kasumov T, Thomas KR, Jobbins KA, David F, Minkler PE, Hoppel CL, Brunengraber H. Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. The Journal of Biological Chemistry. 280: 9265-71. PMID 15611129 DOI: 10.1074/Jbc.M412850200 |
0.474 |
|
| 2005 |
Puchowicz MA, Smith CL, Bomont C, Koshy J, David F, Brunengraber H. Dog model of therapeutic ketosis induced by oral administration of R,S-1,3-butanediol diacetoacetate. The Journal of Nutritional Biochemistry. 11: 281-7. PMID 10876102 DOI: 10.1016/S0955-2863(00)00079-6 |
0.3 |
|
| 2004 |
Bederman IR, Kasumov T, Reszko AE, David F, Brunengraber H, Kelleher JK. In vitro modeling of fatty acid synthesis under conditions simulating the zonation of lipogenic [13C]acetyl-CoA enrichment in the liver. The Journal of Biological Chemistry. 279: 43217-26. PMID 15284243 DOI: 10.1074/jbc.M403837200 |
0.779 |
|
| 2004 |
Bederman IR, Reszko AE, Kasumov T, David F, Wasserman DH, Kelleher JK, Brunengraber H. Zonation of labeling of lipogenic acetyl-CoA across the liver: implications for studies of lipogenesis by mass isotopomer analysis. The Journal of Biological Chemistry. 279: 43207-16. PMID 15284242 DOI: 10.1074/jbc.M403838200 |
0.801 |
|
| 2004 |
Reszko AE, Kasumov T, David F, Thomas KR, Jobbins KA, Cheng JF, Lopaschuk GD, Dyck JR, Diaz M, Des Rosiers C, Stanley WC, Brunengraber H. Regulation of malonyl-CoA concentration and turnover in the normal heart. The Journal of Biological Chemistry. 279: 34298-301. PMID 15181001 DOI: 10.1074/Jbc.M405488200 |
0.776 |
|
| 2004 |
Reszko AE, Kasumov T, David F, Jobbins KA, Thomas KR, Hoppel CL, Brunengraber H, Des Rosiers C. Peroxisomal fatty acid oxidation is a substantial source of the acetyl moiety of malonyl-CoA in rat heart. The Journal of Biological Chemistry. 279: 19574-9. PMID 14982940 DOI: 10.1074/Jbc.M400162200 |
0.8 |
|
| 2004 |
Kasumov T, Brunengraber LL, Comte B, Puchowicz MA, Jobbins K, Thomas K, David F, Kinman R, Wehrli S, Dahms W, Kerr D, Nissim I, Brunengraber H. New secondary metabolites of phenylbutyrate in humans and rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 10-9. PMID 14709615 DOI: 10.1124/Dmd.32.1.10 |
0.386 |
|
| 2003 |
Reszko AE, Kasumov T, Pierce BA, David F, Hoppel CL, Stanley WC, Des Rosiers C, Brunengraber H. Assessing the reversibility of the anaplerotic reactions of the propionyl-CoA pathway in heart and liver. The Journal of Biological Chemistry. 278: 34959-65. PMID 12824185 DOI: 10.1074/Jbc.M302013200 |
0.792 |
|
| 2003 |
Martini WZ, Stanley WC, Huang H, Rosiers CD, Hoppel CL, Brunengraber H. Quantitative assessment of anaplerosis from propionate in pig heart in vivo. American Journal of Physiology. Endocrinology and Metabolism. 284: E351-6. PMID 12388135 DOI: 10.1152/Ajpendo.00354.2002 |
0.369 |
|
| 2002 |
Poirier M, Vincent G, Reszko AE, Bouchard B, Kelleher JK, Brunengraber H, Des Rosiers C. Probing the link between citrate and malonyl-CoA in perfused rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1379-86. PMID 12234788 DOI: 10.1152/Ajpheart.00244.2002 |
0.804 |
|
| 2002 |
Roe CR, Sweetman L, Roe DS, David F, Brunengraber H. Treatment of cardiomyopathy and rhabdomyolysis in long-chain fat oxidation disorders using an anaplerotic odd-chain triglyceride. The Journal of Clinical Investigation. 110: 259-69. PMID 12122118 DOI: 10.1172/Jci15311 |
0.329 |
|
| 2002 |
Comte B, Kasumov T, Pierce BA, Puchowicz MA, Scott ME, Dahms W, Kerr D, Nissim I, Brunengraber H. Identification of phenylbutyrylglutamine, a new metabolite of phenylbutyrate metabolism in humans. Journal of Mass Spectrometry : Jms. 37: 581-90. PMID 12112740 DOI: 10.1002/Jms.316 |
0.347 |
|
| 2002 |
Kasumov T, Martini WZ, Reszko AE, Bian F, Pierce BA, David F, Roe CR, Brunengraber H. Assay of the concentration and (13)C isotopic enrichment of propionyl-CoA, methylmalonyl-CoA, and succinyl-CoA by gas chromatography-mass spectrometry. Analytical Biochemistry. 305: 90-6. PMID 12018949 DOI: 10.1006/Abio.2002.5639 |
0.802 |
|
| 2001 |
Reszko AE, Kasumov T, Comte B, Pierce BA, David F, Bederman IR, Deutsch J, Des Rosiers C, Brunengraber H. Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry. Analytical Biochemistry. 298: 69-75. PMID 11673897 DOI: 10.1006/Abio.2001.5349 |
0.796 |
|
| 2001 |
Panchal AR, Comte B, Huang H, Dudar B, Roth B, Chandler M, Des Rosiers C, Brunengraber H, Stanley WC. Acute hibernation decreases myocardial pyruvate carboxylation and citrate release. American Journal of Physiology. Heart and Circulatory Physiology. 281: H1613-20. PMID 11557551 DOI: 10.1152/Ajpheart.2001.281.4.H1613 |
0.327 |
|
| 2001 |
Panchal A, Comte B, Huang H, Dudar B, Roth B, Chandler M, Brunengraber H, Stanley W. Malic enzyme inhibition does not effect pyruvate carboxylation in the heart Journal of Molecular and Cellular Cardiology. 33: A174. DOI: 10.1016/S0022-2828(01)90667-4 |
0.315 |
|
| 2000 |
Panchal AR, Comte B, Huang H, Kerwin T, Darvish A, des Rosiers C, Brunengraber H, Stanley WC. Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2390-8. PMID 11045976 DOI: 10.1152/Ajpheart.2000.279.5.H2390 |
0.445 |
|
| 2000 |
Wajngot A, Chandramouli V, Schumann WC, Brunengraber H, Efendic S, Landau BR. A probing dose of phenylacetate does not affect glucose production and gluconeogenesis in humans. Metabolism: Clinical and Experimental. 49: 1211-4. PMID 11016906 DOI: 10.1053/Meta.2000.8601 |
0.335 |
|
| 2000 |
Yang D, Brunengraber H. Glutamate, a window on liver intermediary metabolism. The Journal of Nutrition. 130: 991S-4S. PMID 10736368 DOI: 10.1093/Jn/130.4.991S |
0.484 |
|
| 2000 |
Yang D, Hazey JW, David F, Singh J, Rivchum R, Streem JM, Halperin ML, Brunengraber H. Integrative physiology of splanchnic glutamine and ammonium metabolism. American Journal of Physiology. Endocrinology and Metabolism. 278: E469-76. PMID 10710501 DOI: 10.1152/Ajpendo.2000.278.3.E469 |
0.392 |
|
| 1999 |
Puchowicz MA, Bederman IR, Comte B, Yang D, David F, Stone E, Jabbour K, Wasserman DH, Brunengraber H. Zonation of acetate labeling across the liver: implications for studies of lipogenesis by MIDA. The American Journal of Physiology. 277: E1022-7. PMID 10600790 DOI: 10.1152/Ajpendo.1999.277.6.E1022 |
0.724 |
|
| 1999 |
Previs SF, Brunengraber H. Methods for measuring gluconeogenesis in vivo. Current Opinion in Clinical Nutrition and Metabolic Care. 1: 461-5. PMID 10565394 DOI: 10.1097/00075197-199809000-00016 |
0.396 |
|
| 1999 |
Yang D, Puchowicz MA, David F, Powers L, Halperin ML, Brunengraber H. 15N enrichment of ammonium, glutamine-amide and urea, measured via mass isotopomer analysis of hexamethylenetetramine. Journal of Mass Spectrometry : Jms. 34: 1130-6. PMID 10548807 DOI: 10.1002/(Sici)1096-9888(199911)34:11<1130::Aid-Jms871>3.0.Co;2-Y |
0.362 |
|
| 1998 |
Previs SF, Hallowell PT, Neimanis KD, David F, Brunengraber H. Limitations of the mass isotopomer distribution analysis of glucose to study gluconeogenesis. Heterogeneity of glucose labeling in incubated hepatocytes. The Journal of Biological Chemistry. 273: 16853-9. PMID 9642245 DOI: 10.1074/Jbc.273.27.16853 |
0.463 |
|
| 1998 |
Landau BR, Wahren J, Ekberg K, Previs SF, Yang D, Brunengraber H. Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-13C6]glucose. The American Journal of Physiology. 274: E954-61. PMID 9612255 DOI: 10.1152/Ajpendo.1998.274.5.E954 |
0.329 |
|
| 1998 |
Yang D, Diraison F, Beylot M, Brunengraber DZ, Samols MA, Anderson VE, Brunengraber H. Assay of low deuterium enrichment of water by isotopic exchange with [U- 13C3]acetone and gas chromatography-mass spectrometry Analytical Biochemistry. 258: 315-321. PMID 9570847 DOI: 10.1006/Abio.1998.2632 |
0.347 |
|
| 1998 |
Diraison F, Large V, Brunengraber H, Beylot M. Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycaemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM. Diabetologia. 41: 212-20. PMID 9498656 DOI: 10.1007/S001250050892 |
0.369 |
|
| 1997 |
Verhoeven NM, Schor DS, Previs SF, Brunengraber H, Jakobs C. Stable isotope studies of phytanic acid alpha-oxidation: in vivo production of formic acid. European Journal of Pediatrics. S83-7. PMID 9266223 DOI: 10.1007/Pl00014279 |
0.418 |
|
| 1997 |
Brunengraber H, Kelleher JK, Des Rosiers C. Applications of mass isotopomer analysis to nutrition research. Annual Review of Nutrition. 17: 559-96. PMID 9240940 DOI: 10.1146/Annurev.Nutr.17.1.559 |
0.344 |
|
| 1997 |
Hazey JW, Yang D, Powers L, Previs SF, David F, Beaulieu AD, Puchowicz MA, Potter JL, Palmquist DL, Brunengraber H. Tracing gluconeogenesis with deuterated water: measurement of low deuterium enrichments on carbons 6 and 2 of glucose. Analytical Biochemistry. 248: 158-67. PMID 9177735 DOI: 10.1006/Abio.1997.2068 |
0.407 |
|
| 1997 |
Large V, Brunengraber H, Odeon M, Beylot M. Use of labeling pattern of liver glutamate to calculate rates of citric acid cycle and gluconeogenesis. The American Journal of Physiology. 272: E51-8. PMID 9038851 DOI: 10.1152/ajpendo.1997.272.1.E51 |
0.343 |
|
| 1997 |
Kien CL, Murray RD, Ailabouni A, Powers P, Kepner J, Powers L, Brunengraber H. Stable isotope model for assessing production of short chain fatty acids from colon-derived sugar: application in pigs. The Journal of Nutrition. 126: 3069-76. PMID 9001376 DOI: 10.1093/Jn/126.12.3069 |
0.388 |
|
| 1996 |
Previs SF, Martin SK, Hazey JW, Soloviev MV, Keating AP, Lucas D, David F, Koshy J, Kirschenbaum DW, Tserng KY, Brunengraber H. Contributions of liver and kidneys to glycerol production and utilization in the dog. The American Journal of Physiology. 271: E1118-24. PMID 8997233 DOI: 10.1152/Ajpendo.1996.271.6.E1118 |
0.368 |
|
| 1996 |
Landau BR, Wahren J, Previs SF, Ekberg K, Chandramouli V, Brunengraber H. Glycerol production and utilization in humans: sites and quantitation. The American Journal of Physiology. 271: E1110-7. PMID 8997232 DOI: 10.1152/Ajpendo.1996.271.6.E1110 |
0.43 |
|
| 1996 |
Yang D, Previs SF, Fernandez CA, Dugelay S, Soloviev MV, Hazey JW, Agarwal KC, Levine WC, David F, Rinaldo P, Beylot M, Brunengraber H. Noninvasive probing of citric acid cycle intermediates in primate liver with phenylacetylglutamine American Journal of Physiology - Endocrinology and Metabolism. 270. PMID 8967478 DOI: 10.1152/Ajpendo.1996.270.5.E882 |
0.462 |
|
| 1996 |
Previs SF, Des Rosiers C, Beylot M, David F, Brunengraber H. Assay of the 13C and 2H mass isotopomer distribution of phosphoenolpyruvate by gas chromatography/mass spectrometry. Journal of Mass Spectrometry : Jms. 31: 643-8. PMID 8799298 DOI: 10.1002/(Sici)1096-9888(199606)31:6<643::Aid-Jms335>3.0.Co;2-B |
0.487 |
|
| 1996 |
Fernandez CA, Des Rosiers C, Previs SF, David F, Brunengraber H. Correction of 13C mass isotopomer distributions for natural stable isotope abundance Journal of Mass Spectrometry. 31: 255-262. PMID 8799277 DOI: 10.1002/(Sici)1096-9888(199603)31:3<255::Aid-Jms290>3.0.Co;2-3 |
0.418 |
|
| 1995 |
Beylot M, Soloviev MV, David F, Landau BR, Brunengraber H. Tracing hepatic gluconeogenesis relative to citric acid cycle activity in vitro and in vivo. Comparisons in the use of [3-13C]lactate, [2-13C]acetate, and alpha-keto[3-13C]isocaproate. The Journal of Biological Chemistry. 270: 1509-14. PMID 7829478 DOI: 10.1074/Jbc.270.4.1509 |
0.484 |
|
| 1995 |
Des Rosiers C, Di Donato L, Comte B, Laplante A, Marcoux C, David F, Fernandez CA, Brunengraber H. Isotopomer analysis of citric acid cycle and gluconeogenesis in rat liver. Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis. The Journal of Biological Chemistry. 270: 10027-36. PMID 7730304 DOI: 10.1074/Jbc.270.17.10027 |
0.459 |
|
| 1995 |
Previs SF, Fernandez CA, Yang D, Soloviev MV, David F, Brunengraber H. Limitations of the mass isotopomer distribution analysis of glucose to study gluconeogenesis: Substrate cycling between glycerol and triose phosphates in liver Journal of Biological Chemistry. 270: 19806-19815. PMID 7649990 DOI: 10.1074/Jbc.270.34.19806 |
0.484 |
|
| 1995 |
Landau BR, Fernandez CA, Previs SF, Ekberg K, Chandramouli V, Wahren J, Kalhan SC, Brunengraber H. A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans. The American Journal of Physiology. 269: E18-26. PMID 7631774 DOI: 10.1152/Ajpendo.1995.269.1.E18 |
0.379 |
|
| 1995 |
Desrochers S, Quinze K, Dugas H, Dubreuil P, Bomont C, David F, Agarwal KC, Kumar A, Soloviev MV, Powers L, Landau BR, Brunengraber H. R,S-1,3-butanediol acetoacetate esters, potential alternates to lipid emulsions for total parenteral nutrition The Journal of Nutritional Biochemistry. 6: 111-118. DOI: 10.1016/0955-2863(94)00011-A |
0.323 |
|
| 1995 |
Powers L, Osborn MK, Yang D, Kien CL, Murray RD, Beylot M, Brunengraber H. Assay of the concentration and stable isotope enrichment of short-chain fatty acids by gas chromatography/mass spectrometry Journal of Mass Spectrometry. 30: 747-754. DOI: 10.1002/Jms.1190300514 |
0.503 |
|
| 1994 |
Previs SF, Ciraolo ST, Fernandez CA, Beylot M, Agarwal KC, Soloviev MV, Brunengraber H. Use of [6,6-2H2]Glucose and of Low-Enrichment [U-13C6]-Glucose for Sequential or Simultaneous Measurements of Glucose Turnover by Gas Chromatography-Mass Spectrometry Analytical Biochemistry. 218: 192-196. PMID 8053553 DOI: 10.1006/Abio.1994.1159 |
0.351 |
|
| 1994 |
David F, Beylot M, Reider MW, Anderson VE, Brunengraber H. Assay of the Concentration and 13C Enrichment of Acetate and Acetyl-CoA by Gas Chromatography-Mass Spectrometry Analytical Biochemistry. 218: 143-148. PMID 8053548 DOI: 10.1006/Abio.1994.1153 |
0.43 |
|
| 1994 |
Beylot M, David F, Khalfallah Y, Normand S, Large V, Brunengraber H. Determination of (13C) urea enrichment by gas chromatography/mass spectrometry and gas chromatography/isotope ratio mass spectrometry. Biological Mass Spectrometry. 23: 510-3. PMID 7918692 DOI: 10.1002/Bms.1200230808 |
0.409 |
|
| 1994 |
Yang D, Previs S, Fernandez C, Soloviev M, David F, Dugelay S, Brunengraber H. Validation of the Use of Urinary Phenylacetyl-Glutamine to Assess the Labeling Pattern of Liver Citric Acid Cycle Intermediates in Monkeys Ifac Proceedings Volumes. 27: 417-418. DOI: 10.1016/S1474-6670(17)46288-4 |
0.391 |
|
| 1994 |
Des Rosiers C, Di Donato L, Comte B, Laplante A, Marcoux C, David F, Brunengraber H. Rates of Gluconeogenesis (GNG) in Rat Livers Perfused with [U- 13 C 3 ]lactate and [U- 13 C]pyruvate: Estimating Isotope Dilution by Mass Isotopomer Analysis Ifac Proceedings Volumes. 27: 375-376. DOI: 10.1016/S1474-6670(17)46268-9 |
0.342 |
|
| 1993 |
Yang D, Beylot M, Agarwal KC, Soloviev MV, Brunengraber H. Assay of the human liver citric acid cycle probe phenylacetylglutamine and of phenylacetate in plasma by gas chromatography-mass spectrometry. Analytical Biochemistry. 212: 277-82. PMID 8368503 DOI: 10.1006/Abio.1993.1323 |
0.461 |
|
| 1993 |
Beylot M, Previs SF, David F, Brunengraber H. Determination of the 13C-labeling pattern of glucose by gas chromatography-mass spectrometry. Analytical Biochemistry. 212: 526-31. PMID 8214596 DOI: 10.1006/Abio.1993.1363 |
0.399 |
|
| 1993 |
Zhang Y, Agarwal KC, Beylot M, Soloviev MV, David F, Reider M, Tserng KY, Brunengraber H. Assay of the acetyl-CoA probe acetyl-sulfamethoxazole and of sulfamethoxazole by gas chromatography-mass spectrometry. Analytical Biochemistry. 212: 481-6. PMID 8214590 DOI: 10.1006/Abio.1993.1357 |
0.402 |
|
| 1993 |
Beylot M, David F, Brunengraber H. Determination of the 13C-labeling pattern of glutamate by gas chromatography-mass spectrometry. Analytical Biochemistry. 212: 532-6. PMID 8105720 DOI: 10.1006/Abio.1993.1364 |
0.39 |
|
| 1992 |
Desrochers S, David F, Garneau M, Jette M, Brunengraber H. Metabolism of R- and S-1,3-butanediol in perfused livers from meal-fed and starved rats Biochemical Journal. 285: 647-653. PMID 1637355 DOI: 10.1042/Bj2850647 |
0.385 |
|
| 1992 |
Montgomery JA, Des Rosiers C, Brunengraber H. Biosynthesis and characterization of 3-hydroxyalkan-2-ones and 2,3-alkanediols: potential products of aldehyde metabolism. Biological Mass Spectrometry. 21: 242-8. PMID 1525185 DOI: 10.1002/Bms.1200210504 |
0.404 |
|
| 1990 |
Des Rosiers C, Montgomery JA, Garneau M, David F, Mamer OA, Daloze P, Toffolo G, Cobelli C, Landau BR, Brunengraber H. Pseudoketogenesis in hepatectomized dogs. The American Journal of Physiology. 258: E519-28. PMID 2316645 DOI: 10.1152/Ajpendo.1990.258.3.E519 |
0.329 |
|
| 1987 |
Landau BR, Brunengraber H. The role of acetone in the conversion of fat to carbohydrate Trends in Biochemical Sciences. 12: 113-114. DOI: 10.1016/0968-0004(87)90051-X |
0.302 |
|
| 1985 |
Landau BR, Brunengraber H. Shunt pathway of mevalonate metabolism. Methods in Enzymology. 110: 100-14. PMID 3927111 DOI: 10.1016/S0076-6879(85)10065-0 |
0.455 |
|
| 1984 |
Tomera JF, Skipper PL, Wishnok JS, Tannenbaum SR, Brunengraber H. Inhibition of N-nitrosodimethylamine metabolism by ethanol and other inhibitors in the isolated perfused rat liver. Carcinogenesis. 5: 113-6. PMID 6690081 DOI: 10.1093/Carcin/5.1.113 |
0.357 |
|
| 1983 |
Tomera JF, McCaffrey PG, Brunengraber H. Rates of catabolism calculated from 14CO2 production: artifacts and realities. Pharmacology, Biochemistry, and Behavior. 285-8. PMID 6415670 DOI: 10.1016/0091-3057(83)90187-9 |
0.386 |
|
| 1983 |
Tomera JF, Kopito RR, Brunengraber H. Assessment of the flux of mitochondrial acetyl-CoA in liver and kidney by using the differential production of 14CO2 from tracers of (1-14C)- and (2-14C)-labelled 4-methyl-2-oxovalerate. The Biochemical Journal. 210: 265-8. PMID 6405741 DOI: 10.1042/bj2100265 |
0.314 |
|
| 1982 |
Patton GM, Cann S, Brunengraber H, Lowenstein JM. Separation of methyl esters of fatty acids by gas chromatography on capillary columns, including the separation of deuterated from nondeuterated fatty acids. Methods in Enzymology. 72: 8-20. PMID 6273693 DOI: 10.1016/S0076-6879(81)72004-4 |
0.356 |
|
| 1980 |
Goldberg RP, Brunengraber H. Contributions of cytosolic and mitochondrial acetyl-CoA syntheses to the activation of lipogenic acetate in rat liver. Advances in Experimental Medicine and Biology. 132: 413-8. PMID 6106997 DOI: 10.1007/978-1-4757-1419-7_41 |
0.313 |
|
| 1978 |
Brunengraber H, Boutry M, Lowenstein JM. Fatty acid, 3-beta-hydroxysterol, and ketone synthesis in the perfused rat liver. Effects of (--)-hydroxycitrate and oleate. European Journal of Biochemistry. 82: 373-84. PMID 624277 DOI: 10.1111/j.1432-1033.1978.tb12032.x |
0.35 |
|
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