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Barbara A. Seaton - Publications

Affiliations: 
Physiology and Biophysics Boston University, Boston, MA, United States 
Area:
Medical Biophysics
Website:
http://www.bumc.bu.edu/phys-biophys/people/faculty/seaton/
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59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 van Eijk M, Rynkiewicz MJ, Khatri K, Leymarie N, Zaia J, White MR, Hartshorn KL, Cafarella TR, Van Die I, Hessing M, Seaton BA, Haagsman HP. Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus. The Journal of Biological Chemistry. PMID 29769321 DOI: 10.1074/Jbc.Ra117.001430  0.345
2017 Rynkiewicz MJ, Wu H, Cafarella TR, Nikolaidis NM, Head JF, Seaton BA, McCormack FX. Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop. Biochemistry. PMID 28719181 DOI: 10.1021/acs.biochem.6b01313  0.349
2016 Goh BC, Wu H, Rynkiewicz MJ, Schulten K, Seaton BA, McCormack FX. Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations. Biochemistry. PMID 27324153 DOI: 10.1021/Acs.Biochem.6B00048  0.351
2015 Goh BC, Rynkiewicz MJ, McCormack FX, Seaton BA, Schulten K. Unraveling the Dual Role of Surfactant Protein a at Atomistic Detail Biophysical Journal. 108: 255a-256a. DOI: 10.1016/J.Bpj.2014.11.1413  0.408
2013 Goh BC, Zou X, Rynkiewicz MJ, Seaton BA, Schulten K. Effect of Two Point Mutations in Lung Surfactant Protein-D on Enhancing its Inhibition Activity Against Influenza a Virus Biophysical Journal. 104: 556a. DOI: 10.1016/J.Bpj.2012.11.3080  0.372
2012 van Eijk M, Rynkiewicz MJ, White MR, Hartshorn KL, Zou X, Schulten K, Luo D, Crouch EC, Cafarella TR, Head JF, Haagsman HP, Seaton BA. A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D. The Journal of Biological Chemistry. 287: 26666-77. PMID 22685299 DOI: 10.1074/Jbc.M112.368571  0.404
2012 Yu P, Strug I, Cafarella TR, Seaton BA, Krantz A. Site-specific crosslinking of annexin proteins by 1,4-benzoquinone: a novel crosslinker for the formation of protein dimers and diverse protein conjugates. Organic & Biomolecular Chemistry. 10: 4500-4. PMID 22573340 DOI: 10.1039/C2Ob25460C  0.376
2012 Chong Goh B, Zou X, Rynkiewicz MJ, Seaton BA, Schulten KJ. Mechanism of Interaction Between Lung Surfactant Protein-D and Influenza A Virus Hemagglutinin Biophysical Journal. 102: 63a. DOI: 10.1016/J.Bpj.2011.11.373  0.39
2011 Crouch E, Nikolaidis N, McCormack FX, McDonald B, Allen K, Rynkiewicz MJ, Cafarella TM, White M, Lewnard K, Leymarie N, Zaia J, Seaton BA, Hartshorn KL. Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo. The Journal of Biological Chemistry. 286: 40681-92. PMID 21965658 DOI: 10.1074/Jbc.M111.300673  0.377
2011 van Eijk M, Bruinsma L, Hartshorn KL, White MR, Rynkiewicz MJ, Seaton BA, Hemrika W, Romijn RA, van Balkom BW, Haagsman HP. Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses. The Journal of Biological Chemistry. 286: 20137-51. PMID 21489996 DOI: 10.1074/Jbc.M111.224469  0.326
2011 Shang F, Rynkiewicz MJ, McCormack FX, Wu H, Cafarella TM, Head JF, Seaton BA. Crystallographic complexes of surfactant protein A and carbohydrates reveal ligand-induced conformational change. The Journal of Biological Chemistry. 286: 757-65. PMID 21047777 DOI: 10.1074/Jbc.M110.175265  0.643
2011 Gourion-Arsiquaud S, Seaton BA, Heads JF, McCormack FX, Flach CR, Mendelsohn R. Unraveling the Specific Interactions of Collectin with Lipopolysaccharides Biophysical Journal. 100: 511a. DOI: 10.1016/J.Bpj.2010.12.2988  0.445
2011 Rynkiewicz MJ, Luo D, Leymarie N, Crouch EC, Hartshorn KL, Head JF, McCormack FX, van Eijk M, Zaia J, Seaton BA. Mechanisms of Interaction Between Lung Collectins and Influenza a Virus Hemagglutinin Biophysical Journal. 100: 214a-215a. DOI: 10.1016/J.Bpj.2010.12.1384  0.363
2010 Seaton BA, Crouch EC, McCormack FX, Head JF, Hartshorn KL, Mendelsohn R. Review: Structural determinants of pattern recognition by lung collectins. Innate Immunity. 16: 143-50. PMID 20423923 DOI: 10.1177/1753425910368716  0.423
2009 Shi X, Shao C, Zhang X, Zambonelli C, Redfield AG, Head JF, Seaton BA, Roberts MF. Modulation of Bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface. The Journal of Biological Chemistry. 284: 15607-18. PMID 19369255 DOI: 10.1074/Jbc.M901601200  0.658
2009 Crouch E, Hartshorn K, Horlacher T, McDonald B, Smith K, Cafarella T, Seaton B, Seeberger PH, Head J. Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343. Biochemistry. 48: 3335-45. PMID 19249874 DOI: 10.1021/Bi8022703  0.439
2009 Cai J, Crouch EC, Seaton BA, Roberts MF. Interaction of Lung Surfactant Protein A with Phosphatidylcholine Vesicles Biophysical Journal. 96: 611a. DOI: 10.1016/J.Bpj.2008.12.3231  0.377
2009 Mao G, Wang L, Brauner JW, McCormack FX, Crouch E, Seaton B, Head J, Smith K, Flach CR, Mendelsohn R. IRRAS Studies of the Host Defense Effect of Pulmonary Surfactants SP-A and SP-D Biophysical Journal. 96: 595a. DOI: 10.1016/J.Bpj.2008.12.3115  0.371
2008 Wang L, Brauner JW, Mao G, Crouch E, Seaton B, Head J, Smith K, Flach CR, Mendelsohn R. Interaction of recombinant surfactant protein D with lipopolysaccharide: conformation and orientation of bound protein by IRRAS and simulations. Biochemistry. 47: 8103-13. PMID 18620419 DOI: 10.1021/Bi800626H  0.42
2008 Guo S, Zhang X, Seaton BA, Roberts MF. Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C. Biochemistry. 47: 4201-10. PMID 18345643 DOI: 10.1021/Bi702269U  0.466
2008 Shao C, Novakovic VA, Head JF, Seaton BA, Gilbert GE. Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif. The Journal of Biological Chemistry. 283: 7230-41. PMID 18160406 DOI: 10.1074/Jbc.M705195200  0.605
2008 Wang H, Head J, Kosma P, Brade H, Müller-Loennies S, Sheikh S, McDonald B, Smith K, Cafarella T, Seaton B, Crouch E. Recognition of heptoses and the inner core of bacterial lipopolysaccharides by surfactant protein d. Biochemistry. 47: 710-20. PMID 18092821 DOI: 10.1021/Bi7020553  0.374
2007 Crouch E, McDonald B, Smith K, Roberts M, Mealy T, Seaton B, Head J. Critical role of Arg/Lys343 in the species-dependent recognition of phosphatidylinositol by pulmonary surfactant protein D. Biochemistry. 46: 5160-9. PMID 17417879 DOI: 10.1021/Bi700037X  0.461
2007 Shao C, Shi X, Wehbi H, Zambonelli C, Head JF, Seaton BA, Roberts MF. Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C. The Journal of Biological Chemistry. 282: 9228-35. PMID 17213187 DOI: 10.1074/Jbc.M610918200  0.646
2006 Shao C, Zhang F, Kemp MM, Linhardt RJ, Waisman DM, Head JF, Seaton BA. Crystallographic analysis of calcium-dependent heparin binding to annexin A2. The Journal of Biological Chemistry. 281: 31689-95. PMID 16882661 DOI: 10.1074/Jbc.M604502200  0.6
2006 Crouch E, McDonald B, Smith K, Cafarella T, Seaton B, Head J. Contributions of phenylalanine 335 to ligand recognition by human surfactant protein D: ring interactions with SP-D ligands. The Journal of Biological Chemistry. 281: 18008-14. PMID 16636058 DOI: 10.1074/Jbc.M601749200  0.427
2006 Shao C, Head JF, Seaton BA, Gilbert GE. Crystal Structure of the C2 Domain of Lactadherin and Computational Docking of Phosphatidyl-L-Serine. Blood. 108: 195-195. DOI: 10.1182/Blood.V108.11.195.195  0.618
2003 Huang M, Rigby AC, Morelli X, Grant MA, Huang G, Furie B, Seaton B, Furie BC. Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins. Nature Structural Biology. 10: 751-6. PMID 12923575 DOI: 10.1038/Nsb971  0.436
2003 Head JF, Mealy TR, McCormack FX, Seaton BA. Crystal structure of trimeric carbohydrate recognition and neck domains of surfactant protein A. The Journal of Biological Chemistry. 278: 43254-60. PMID 12913002 DOI: 10.1074/Jbc.M305628200  0.5
2003 Stieglitz KA, Seaton BA, Head JF, Stec B, Roberts MF. Unexpected similarity in regulation between an archaeal inositol monophosphatase/fructose bisphosphatase and chloroplast fructose bisphosphatase. Protein Science : a Publication of the Protein Society. 12: 760-7. PMID 12649434 DOI: 10.1110/Ps.0236003  0.659
2003 Mo Y, Campos B, Mealy TR, Commodore L, Head JF, Dedman JR, Seaton BA. Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces. The Journal of Biological Chemistry. 278: 2437-43. PMID 12401794 DOI: 10.1074/Jbc.M210286200  0.345
2002 Stieglitz KA, Johnson KA, Yang H, Roberts MF, Seaton BA, Head JF, Stec B. Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop. The Journal of Biological Chemistry. 277: 22863-74. PMID 11940584 DOI: 10.1074/Jbc.M201042200  0.688
2001 Stieglitz KA, Seaton BA, Roberts MF. Binding of proteolytically processed phospholipase D from Streptomyces chromofuscus to phosphatidylcholine membranes facilitates vesicle aggregation and fusion. Biochemistry. 40: 13954-63. PMID 11705386 DOI: 10.1021/Bi011338O  0.709
2001 Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF. The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution. Nature Structural Biology. 8: 710-4. PMID 11473263 DOI: 10.1038/90429  0.354
2001 Capila I, Hernáiz MJ, Mo YD, Mealy TR, Campos B, Dedman JR, Linhardt RJ, Seaton BA. Annexin V--heparin oligosaccharide complex suggests heparan sulfate--mediated assembly on cell surfaces. Structure (London, England : 1993). 9: 57-64. PMID 11342135 DOI: 10.1016/S0969-2126(00)00549-9  0.457
2001 Kaetzel MA, Mo YD, Mealy TR, Campos B, Bergsma-Schutter W, Brisson A, Dedman JR, Seaton BA. Phosphorylation mutants elucidate the mechanism of annexin IV-mediated membrane aggregation Biochemistry. 40: 4192-4199. PMID 11300800 DOI: 10.1021/Bi002507S  0.376
1999 Campos B, Wang S, Retzinger GS, Kaetzel MA, Seaton BA, Karin NJ, Johnson JD, Dedman JR. Mutation of highly conserved arginine residues disrupts the structure and function of Annexin V Archives of Medical Research. 30: 360-367. PMID 10596454 DOI: 10.1016/S0188-0128(99)00040-8  0.448
1999 Stieglitz K, Seaton B, Roberts MF. The role of interfacial binding in the activation of Streptomyces chromofuscus phospholipase D by phosphatidic acid. The Journal of Biological Chemistry. 274: 35367-74. PMID 10585404 DOI: 10.1074/Jbc.274.50.35367  0.711
1999 Capila I, VanderNoot VA, Mealy TR, Seaton BA, Linhardt RJ. Interaction of heparin with annexin V. Febs Letters. 446: 327-30. PMID 10100868 DOI: 10.1016/S0014-5793(99)00245-8  0.399
1999 Wu F, Flach CR, Seaton BA, Mealy TR, Mendelsohn R. Stability of annexin V in ternary complexes with CA2+ and anionic phospholipids: IR studies of monolayer and bulk phases Biochemistry. 38: 792-799. PMID 9888820 DOI: 10.1021/Bi9819677  0.359
1998 Wu F, Gericke A, Flach CR, Mealy TR, Seaton BA, Mendelsohn R. Domain structure and molecular conformation in annexin V/1,2- dimyristoyl-sn-glycero-3-phosphate/Ca2+ aqueous monolayers: A Brewster angle microscopy/infrared reflection-absorption spectroscopy study Biophysical Journal. 74: 3273-3281. PMID 9635781 DOI: 10.1016/S0006-3495(98)78034-8  0.375
1998 Campos B, Mo YD, Mealy TR, Li CW, Swairjo MA, Balch C, Head JF, Retzinger G, Dedman JR, Seaton BA. Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components Biochemistry. 37: 8004-8010. PMID 9609693 DOI: 10.1021/Bi973142N  0.464
1997 Jin L, Seaton BA, Head JF. Crystal structure at 2.8 Å resolution of anabolic ornithine transcarbamylase from Escherichia coli Nature Structural Biology. 4: 622-625. PMID 9253409 DOI: 10.1038/Nsb0897-622  0.322
1996 Rynkiewicz MJ, Seaton BA. Chemical rescue by guanidine derivatives of an arginine-substituted site-directed mutant of Escherichia coli ornithine transcarbamylase Biochemistry. 35: 16174-16179. PMID 8973189 DOI: 10.1021/Bi961311I  0.317
1995 Swairjo MA, Concha NO, Kaetzel MA, Dedman JR, Seaton BA. Ca2+-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V Nature Structural Biology. 2: 968-974. PMID 7583670 DOI: 10.1038/Nsb1195-968  0.429
1994 Swairjo MA, Seaton BA, Roberts MF. Effect of vesicle composition and curvature on the dissociation of phosphatidic acid in small unilamellar vesicles--a 31P-NMR study. Biochimica Et Biophysica Acta. 1191: 354-61. PMID 8172921 DOI: 10.1016/0005-2736(94)90186-4  0.325
1994 Swairjo MA, Roberts MF, Campos MB, Dedman JR, Seaton BA. Annexin V binding to the outer leaflet of small unilamellar vesicles leads to altered inner-leaflet properties: 31P- and 1H-NMR studies. Biochemistry. 33: 10944-50. PMID 8086411 DOI: 10.1021/Bi00202A013  0.444
1994 Seaton BA, Head JF. Shaking hands with yourself Nature Structural Biology. 1: 350-351. PMID 7664043 DOI: 10.1038/Nsb0694-350  0.361
1994 Swairjo MA, Seaton BA. Annexin structure and membrane interactions: A molecular perspective Annual Review of Biophysics and Biomolecular Structure. 23: 193-213. PMID 7522665 DOI: 10.1146/Annurev.Bb.23.060194.001205  0.41
1993 Concha NO, Head JF, Kaetzel MA, Dedman JR, Seaton BA. Rat annexin V crystal structure: Ca2+-induced conformational changes Science. 261: 1321-1324. PMID 8362244 DOI: 10.1126/Science.8362244  0.357
1992 Concha NO, Head JF, Kaetzel MA, Dedman JR, Seaton BA. Annexin V forms calcium-dependent trimeric units on phospholipid vesicles Febs Letters. 314: 159-162. PMID 1459245 DOI: 10.1016/0014-5793(92)80964-I  0.387
1991 Davenport RC, Bash PA, Seaton BA, Karplus M, Petsko GA, Ringe D. Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analogue of the intermediate on the reaction pathway. Biochemistry. 30: 5821-6. PMID 2043623 DOI: 10.1021/Bi00238A002  0.528
1990 Ke HM, Thorpe CM, Seaton Ba, Lipscomb WN, Marcus F. Structure refinement of fructose-1,6-bisphosphatase and its fructose 2,6-bisphosphate complex at 2.8 A resolution. Journal of Molecular Biology. 212: 513-39. PMID 2157849 DOI: 10.1016/0022-2836(90)90329-K  0.308
1989 Kataoka M, Head JF, Seaton BA, Engelman DM. Melittin binding causes a large calcium-dependent conformational change in calmodulin Proceedings of the National Academy of Sciences of the United States of America. 86: 6944-6948. PMID 2780551 DOI: 10.1073/Pnas.86.18.6944  0.404
1989 Ke H, Thorpe CM, Seaton BA, Marcus F, Lipscomb WN. Molecular structure of fructose-1,6-bisphosphatase at 2.8-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 86: 1475-9. PMID 2537975 DOI: 10.1073/Pnas.86.5.1475  0.304
1985 Lord RC, Petsko GA, Seaton BA, Goodfriend L. Laser Raman spectroscopy of biomolecules: Structural studies of ragweed allergen Ra5 Spectrochimica Acta Part a: Molecular Spectroscopy. 41: 199-203. DOI: 10.1016/0584-8539(85)80097-0  0.373
1984 Seaton BA, Campbell RL, Petsko GA, Rose DR, Edelstein I, Marcus F. Preliminary X-ray crystallographic studies of pig kidney fructose-1,6-bisphosphatase. The Journal of Biological Chemistry. 259: 8915-6. PMID 6086617  0.411
1983 Rose DR, Seaton BA, Petsko GA, Novotný J, Margolies MN, Locke E, Haber E. Crystallization of the Fab fragment of a monoclonal anti-digoxin antibody and its complex with digoxin. Journal of Molecular Biology. 165: 203-6. PMID 6842605 DOI: 10.1016/S0022-2836(83)80252-6  0.383
1983 Seaton BA, Head JF, Lord RC, Petsko GA. Studies of calmodulin structure: laser raman spectroscopy of biomolecules. Biochemistry. 22: 973-8. PMID 6301532 DOI: 10.1021/Bi00273A041  0.513
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