Piet Gros - Publications

Utrecht University, Utrecht, Netherlands 

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Geisbrecht BV, Lambris JD, Gros P. Complement component C3: A structural perspective and potential therapeutic implications. Seminars in Immunology. 101627. PMID 35760703 DOI: 10.1016/j.smim.2022.101627  0.327
2022 De la O Becerra KI, Oosterheert W, van den Bos RM, Xenaki KT, Lorent JH, Ruyken M, Schouten A, Rooijakkers SHM, van Bergen En Henegouwen PMP, Gros P. Multifaceted Activities of Seven Nanobodies against Complement C4b. Journal of Immunology (Baltimore, Md. : 1950). 208: 2207-2219. PMID 35428691 DOI: 10.4049/jimmunol.2100647  0.325
2020 Oosterheert W, Reis J, Gros P, Mattevi A. An Elegant Four-Helical Fold in NOX and STEAP Enzymes Facilitates Electron Transport across Biomembranes-Similar Vehicle, Different Destination. Accounts of Chemical Research. PMID 32815713 DOI: 10.1021/Acs.Accounts.0C00400  0.601
2020 Oosterheert W, Gros P. Cryo-EM structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1. The Journal of Biological Chemistry. PMID 32409586 DOI: 10.1074/Jbc.Ra120.013690  0.374
2019 van den Bos RM, Pearce NM, Granneman J, Brondijk THC, Gros P. Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b. Frontiers in Immunology. 10: 2097. PMID 31552043 DOI: 10.3389/Fimmu.2019.02097  0.482
2019 Sharp TH, Boyle AL, Diebolder CA, Kros A, Koster AJ, Gros P. Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b. Proceedings of the National Academy of Sciences of the United States of America. PMID 31147461 DOI: 10.1073/Pnas.1901841116  0.444
2019 Fenderico N, van Scherpenzeel RC, Goldflam M, Proverbio D, Jordens I, Kralj T, Stryeck S, Bass TZ, Hermans G, Ullman C, Aastrup T, Gros P, Maurice MM. Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells. Nature Communications. 10: 365. PMID 30664649 DOI: 10.2210/Pdb6H15/Pdb  0.303
2018 Oosterheert W, van Bezouwen LS, Rodenburg RNP, Granneman J, Förster F, Mattevi A, Gros P. Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction. Nature Communications. 9: 4337. PMID 30337524 DOI: 10.1038/S41467-018-06817-7  0.56
2018 Mohlin FC, Gros P, Mercier E, Gris JR, Blom AM. Analysis of C3 Gene Variants in Patients With Idiopathic Recurrent Spontaneous Pregnancy Loss. Frontiers in Immunology. 9: 1813. PMID 30131807 DOI: 10.3389/Fimmu.2018.01813  0.346
2018 Ugurlar D, Howes SC, de Kreuk BJ, Koning RI, de Jong RN, Beurskens FJ, Schuurman J, Koster AJ, Sharp TH, Parren PWHI, Gros P. Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement. Science (New York, N.Y.). 359: 794-797. PMID 29449492 DOI: 10.1126/Science.Aao4988  0.441
2017 Xue X, Wu J, Ricklin D, Forneris F, Di Crescenzio P, Schmidt CQ, Granneman J, Sharp TH, Lambris JD, Gros P. Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses. Nature Structural & Molecular Biology. PMID 28671664 DOI: 10.1038/Nsmb.3427  0.71
2017 De Nardis C, Hendriks LJA, Poirier E, Arvinte T, Gros P, Bakker ABH, de Kruif J. A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1. The Journal of Biological Chemistry. PMID 28655766 DOI: 10.1074/Jbc.M117.793497  0.313
2017 Gorham RD, Zwarthoff SA, Xue X, Ruyken M, Józsi M, Gros P, Rooijakkers SH. Functional characterization of alternative pathway C3 and C5 convertase inhibitors Molecular Immunology. 89: 141. DOI: 10.1016/J.Molimm.2017.06.084  0.324
2016 De Nardis C, Lössl P, van den Biggelaar M, Madoori PK, Leloup N, Mertens K, Heck AJ, Gros P. Recombinant Expression of the Full-length Ectodomain of LDL Receptor-related Protein 1 (LRP1) Unravels pH-dependent Conformational Changes and the Stoichiometry of Binding with Receptor-associated Protein (RAP). The Journal of Biological Chemistry. PMID 27956551 DOI: 10.1074/Jbc.M116.758862  0.339
2016 Ricklin D, Reis ES, Mastellos DC, Gros P, Lambris JD. Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense. Immunological Reviews. 274: 33-58. PMID 27782325 DOI: 10.1111/Imr.12500  0.358
2016 Sharp TH, G A Faas F, Koster AJ, Gros P. Imaging complement by phase-plate cryo-electron tomography from initiation to pore formation. Journal of Structural Biology. PMID 27663685 DOI: 10.1016/J.Jsb.2016.09.008  0.34
2016 Wang G, de Jong RN, van den Bremer ET, Beurskens FJ, Labrijn AF, Ugurlar D, Gros P, Schuurman J, Parren PW, Heck AJ. Molecular Basis of Assembly and Activation of Complement Component C1 in Complex with Immunoglobulin G1 and Antigen. Molecular Cell. PMID 27320199 DOI: 10.1016/J.Molcel.2016.05.016  0.406
2016 Sharp TH, Koster AJ, Gros P. Heterogeneous MAC Initiator and Pore Structures in a Lipid Bilayer by Phase-Plate Cryo-electron Tomography. Cell Reports. 15: 1-8. PMID 27052168 DOI: 10.1016/J.Celrep.2016.03.002  0.381
2016 Forneris F, Wu J, Xue X, Ricklin D, Lin Z, Sfyroera G, Tzekou A, Volokhina E, Granneman JC, Hauhart R, Bertram P, Liszewski MK, Atkinson JP, Lambris JD, Gros P. Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode. The Embo Journal. PMID 27013439 DOI: 10.15252/Embj.201593673  0.7
2016 Xue X, Wu J, Forneris F, Ricklin D, Di Crescenzio P, Schmidt C, Granneman J, Lambris JD, Gros P. Structural insights into cofactor activity Immunobiology. 221: 1193. DOI: 10.1016/J.Imbio.2016.06.152  0.682
2015 Berends ET, Gorham RD, Ruyken M, Soppe JA, Orhan H, Aerts PC, de Haas CJ, Gros P, Rooijakkers SH. Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes. Bmc Biology. 13: 93. PMID 26552476 DOI: 10.1186/S12915-015-0203-8  0.386
2014 Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster AJ, Taylor RP, Saphire EO, ... ... Gros P, et al. Complement is activated by IgG hexamers assembled at the cell surface. Science (New York, N.Y.). 343: 1260-3. PMID 24626930 DOI: 10.1126/Science.1248943  0.311
2014 Forneris F, Burnley BT, Gros P. Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D. Acta Crystallographica. Section D, Biological Crystallography. 70: 733-43. PMID 24598742 DOI: 10.1107/S1399004713032549  0.715
2013 Peng WC, de Lau W, Madoori PK, Forneris F, Granneman JC, Clevers H, Gros P. Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling. Plos One. 8: e83110. PMID 24349440 DOI: 10.1371/Journal.Pone.0083110  0.684
2013 Peng WC, de Lau W, Forneris F, Granneman JC, Huch M, Clevers H, Gros P. Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5. Cell Reports. 3: 1885-92. PMID 23809763 DOI: 10.1016/J.Celrep.2013.06.009  0.685
2013 Diebolder C, Koning R, Koster A, Gros P. Structure of C1-antibody complexes determined by cryo-electron tomography Molecular Immunology. 56: 261-262. DOI: 10.1016/J.Molimm.2013.05.065  0.355
2013 Forneris F, Gros P. Complement Factor D Handbook of Proteolytic Enzymes. 3: 2841-2848. DOI: 10.1016/B978-0-12-382219-2.00630-X  0.591
2012 Burnley BT, Afonine PV, Adams PD, Gros P. Modelling dynamics in protein crystal structures by ensemble refinement. Elife. 1: e00311. PMID 23251785 DOI: 10.7554/Elife.00311  0.367
2012 Hadders MA, Bubeck D, Roversi P, Hakobyan S, Forneris F, Morgan BP, Pangburn MK, Llorca O, Lea SM, Gros P. Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9. Cell Reports. 1: 200-7. PMID 22832194 DOI: 10.1016/J.Celrep.2012.02.003  0.723
2012 van Galen J, Olrichs NK, Schouten A, Serrano RL, Nolte-'t Hoen EN, Eerland R, Kaloyanova D, Gros P, Helms JB. Interaction of GAPR-1 with lipid bilayers is regulated by alternative homodimerization. Biochimica Et Biophysica Acta. 1818: 2175-83. PMID 22560898 DOI: 10.1016/J.Bbamem.2012.04.016  0.365
2012 Forneris F, Wu J, Gros P. The modular serine proteases of the complement cascade. Current Opinion in Structural Biology. 22: 333-41. PMID 22560446 DOI: 10.1016/J.Sbi.2012.04.001  0.7
2012 Burnley BT, Afonine PV, Adams PD, Gros P. Author response: Modelling dynamics in protein crystal structures by ensemble refinement Elife. DOI: 10.7554/Elife.00311.029  0.335
2012 Forneris F, Hadders MA, Wu J, Gros P. Modularity and conformational changes as key features of the complement system Acta Crystallographica Section a Foundations of Crystallography. 68: s32-s32. DOI: 10.1107/S0108767312099394  0.628
2012 Brunger AT, Adams PD, DeLano WL, Gros P, Grosse‐Kunstleve RW, Jiang J‐, Pannu NS, Read RJ, Rice LM, Simonson T. CNS, a program system for structure‐determination and refinement International Tables For Crystallography. DOI: 10.1107/97809553602060000860  0.301
2011 Roussel-Jazédé V, Van Gelder P, Sijbrandi R, Rutten L, Otto BR, Luirink J, Gros P, Tommassen J, Van Ulsen P. Channel properties of the translocator domain of the autotransporter Hbp of Escherichia coli. Molecular Membrane Biology. 28: 158-70. PMID 21314477 DOI: 10.3109/09687688.2010.550328  0.313
2011 Forneris F, Ricklin D, Wu J, Tzekou A, Wallace RS, Lambris JD, Gros P. Complement convertase formation based on the structures of C3b in complex with factors B and D Acta Crystallographica Section a Foundations of Crystallography. 67: C23-C24. DOI: 10.1107/S0108767311099545  0.675
2011 Gros P, Forneris F, Hadders M, Wu J. Mechanistic insights into the complement system Acta Crystallographica Section a Foundations of Crystallography. 67: C118-C119. DOI: 10.1107/S0108767311097108  0.66
2011 Burnley T, Afonine P, Adams P, Gros P. Ensemble refinement of protein crystal structures inPHENIX Acta Crystallographica Section a Foundations of Crystallography. 67: C133-C134. DOI: 10.1107/S0108767311096723  0.367
2010 Forneris F, Ricklin D, Wu J, Tzekou A, Wallace RS, Lambris JD, Gros P. Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science (New York, N.Y.). 330: 1816-20. PMID 21205667 DOI: 10.1126/Science.1195821  0.702
2010 Forneris F, Wu J, Wallace RS, Tzekou A, Ricklin D, Lambris JD, Gros P. Crystal structure of C3bB in complex with factor D Molecular Immunology. 47: 2259-2260. DOI: 10.1016/J.Molimm.2010.05.186  0.683
2010 Hadders MA, Pangburn MK, Svergun DI, Gros P. Structural insights into the initiation of the terminal pathway Molecular Immunology. 47: 2257-2258. DOI: 10.1016/J.Molimm.2010.05.180  0.358
2009 Janssen BJ, Gomes L, Koning RI, Svergun DI, Koster AJ, Fritzinger DC, Vogel CW, Gros P. Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex. The Embo Journal. 28: 2469-78. PMID 19574954 DOI: 10.1038/Emboj.2009.184  0.769
2009 Wu J, Wu YQ, Ricklin D, Janssen BJ, Lambris JD, Gros P. Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nature Immunology. 10: 728-33. PMID 19503104 DOI: 10.1038/Ni.1755  0.762
2009 Rooijakkers SH, Wu J, Ruyken M, van Domselaar R, Planken KL, Tzekou A, Ricklin D, Lambris JD, Janssen BJ, van Strijp JA, Gros P. Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor. Nature Immunology. 10: 721-7. PMID 19503103 DOI: 10.1038/Ni.1756  0.763
2009 Rutten L, Wieczorek B, Mannie JP, Kruithof CA, Dijkstra HP, Egmond MR, Lutz M, Klein Gebbink RJ, Gros P, van Koten G. Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 4270-80. PMID 19219875 DOI: 10.1002/Chem.200801995  0.384
2009 Rutten L, Mannie JP, Stead CM, Raetz CR, Reynolds CM, Bonvin AM, Tommassen JP, Egmond MR, Trent MS, Gros P. Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium. Proceedings of the National Academy of Sciences of the United States of America. 106: 1960-4. PMID 19174515 DOI: 10.1073/Pnas.0813064106  0.35
2009 Fritzinger DC, Hew BE, Thorne M, Pangburn MK, Janssen BJ, Gros P, Vogel CW. Functional characterization of human C3/cobra venom factor hybrid proteins for therapeutic complement depletion. Developmental and Comparative Immunology. 33: 105-16. PMID 18760301 DOI: 10.1016/J.Dci.2008.07.006  0.734
2009 Rutten L, Wieczorek B, Mannie J, Kruithof C, Dijkstra H, Egmond M, Lutz M, Klein Gebbink R, Gros P, van Koten G. Cover Picture: Solid-State Structural Characterization of Cutinase-ECE-Pincer-Metal Hybrids (Chem. Eur. J. 17/2009) Chemistry - a European Journal. 15: 4211-4211. DOI: 10.1002/Chem.200990057  0.355
2008 Gros P, Milder FJ, Janssen BJ. Complement driven by conformational changes. Nature Reviews. Immunology. 8: 48-58. PMID 18064050 DOI: 10.1038/Nri2231  0.726
2008 Wu J, Janssen B, Rooijakkers S, Ruyken M, Gomes L, van Strijp J, Gros P. Crystal structure of the C3 convertase complex inhibited by SCIN Molecular Immunology. 45: 4119. DOI: 10.1016/J.Molimm.2008.08.070  0.74
2008 Wu J, Janssen B, Wu Y, Ricklin D, Lambris J, Gros P. Insights into the mechanism of host regulation based on the crystal structure of C3b in complex with factor H domains 1–4 Molecular Immunology. 45: 4098. DOI: 10.1016/J.Molimm.2008.08.010  0.735
2008 Janssen B, Gomes L, Fritzinger D, Vogel C, Meeldijk H, Svergun D, Koning R, Koster A, Gros P. Structure of factor B in complex with cobra venom factor gives insights into convertase formation Molecular Immunology. 45: 4096. DOI: 10.1016/J.Molimm.2008.08.004  0.716
2008 Rooijakkers S, Wu J, Ruyken M, van Domselaar R, Janssen B, Gomes L, Gros P, van Strijp J. Convertase stabilisation by staphylococcal complement inhibitor Molecular Immunology. 45: 4095. DOI: 10.1016/J.Molimm.2008.08.002  0.667
2007 Hadders MA, Beringer DX, Gros P. Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense. Science (New York, N.Y.). 317: 1552-4. PMID 17872444 DOI: 10.1126/Science.1147103  0.379
2007 Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA. Structural insights into the Slit-Robo complex. Proceedings of the National Academy of Sciences of the United States of America. 104: 14923-8. PMID 17848514 DOI: 10.1073/Pnas.0705310104  0.408
2007 Arlaud GJ, Barlow PN, Gaboriaud C, Gros P, Narayana SV. Deciphering complement mechanisms: the contributions of structural biology. Molecular Immunology. 44: 3809-22. PMID 17768099 DOI: 10.1016/J.Molimm.2007.06.147  0.38
2007 Rooijakkers SH, Milder FJ, Bardoel BW, Ruyken M, van Strijp JA, Gros P. Staphylococcal complement inhibitor: structure and active sites. Journal of Immunology (Baltimore, Md. : 1950). 179: 2989-98. PMID 17709514 DOI: 10.4049/Jimmunol.179.5.2989  0.432
2007 Morlot C, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA. Production of Slit2 LRR domains in mammalian cells for structural studies and the structure of human Slit2 domain 3. Acta Crystallographica. Section D, Biological Crystallography. 63: 961-8. PMID 17704564 DOI: 10.1107/S0907444907035470  0.359
2007 Janssen BJ, Read RJ, Brünger AT, Gros P. Crystallography: crystallographic evidence for deviating C3b structure. Nature. 448: E1-2; discussion E2-. PMID 17687277 DOI: 10.1038/Nature06102  0.694
2007 Janssen BJ, Halff EF, Lambris JD, Gros P. Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition. The Journal of Biological Chemistry. 282: 29241-7. PMID 17684013 DOI: 10.1074/Jbc.M704587200  0.773
2007 Morlot C, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA. Cloning, expression, crystallization and preliminary X-ray analysis of the first two Ig domains from human roundabout 1 (Robo1). Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 689-91. PMID 17671369 DOI: 10.1107/S1744309107033027  0.345
2007 Milder FJ, Gomes L, Schouten A, Janssen BJ, Huizinga EG, Romijn RA, Hemrika W, Roos A, Daha MR, Gros P. Factor B structure provides insights into activation of the central protease of the complement system. Nature Structural & Molecular Biology. 14: 224-8. PMID 17310251 DOI: 10.1038/Nsmb1210  0.747
2007 Janssen BJ, Gros P. Structural insights into the central complement component C3. Molecular Immunology. 44: 3-10. PMID 16875735 DOI: 10.1016/J.MOLIMM.2006.06.017  0.768
2007 Janssen BJ, Halff E, Lambris JD, Gros P. Structure of C3c in complex with compstatin reveals a new mechanism of complement inhibition Molecular Immunology. 44: 3930. DOI: 10.1016/J.Molimm.2007.06.053  0.772
2007 Rooijakkers S, Milder F, Bardoel B, Ruyken M, van Roon J, Gros P, van Strijp J. Staphylococcal complement inhibitor (SCIN): Structure and active site Molecular Immunology. 44: 233. DOI: 10.1016/J.Molimm.2006.07.201  0.363
2007 Katragadda M, Sfyroera G, Paola M, Janssen BJ, Gros P, Lambris JD. Structure–activity-based design of potent compstatin analogs Molecular Immunology. 44: 192. DOI: 10.1016/J.Molimm.2006.07.108  0.654
2007 Janssen BJ, Christodoulidou A, Katragadda M, Lambris JD, Gros P. Structure of complement component C3b Molecular Immunology. 44: 189. DOI: 10.1016/J.Molimm.2006.07.099  0.716
2007 Fritzinger DC, Hew BE, Janssen BJ, Gros P, Vogel C. Location of amino acid residues important for cobra venom factor function mapped on the three-dimensional structure of complement components C3 and C3c Molecular Immunology. 44: 172. DOI: 10.1016/J.Molimm.2006.07.062  0.716
2006 Janssen BJ, Christodoulidou A, McCarthy A, Lambris JD, Gros P. Structure of C3b reveals conformational changes that underlie complement activity. Nature. 444: 213-6. PMID 17051160 DOI: 10.1038/Nature05172  0.769
2006 Milder FJ, Raaijmakers HC, Vandeputte MD, Schouten A, Huizinga EG, Romijn RA, Hemrika W, Roos A, Daha MR, Gros P. Structure of complement component C2A: implications for convertase formation and substrate binding. Structure (London, England : 1993). 14: 1587-97. PMID 17027507 DOI: 10.1016/J.Str.2006.08.008  0.417
2006 Janssen BJ, Gros P. Conformational complexity of complement component C3. Advances in Experimental Medicine and Biology. 586: 291-312. PMID 16893080 DOI: 10.1007/0-387-34134-X_20  0.768
2006 Rutten L, Geurtsen J, Lambert W, Smolenaers JJ, Bonvin AM, de Haan A, van der Ley P, Egmond MR, Gros P, Tommassen J. Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. 103: 7071-6. PMID 16632613 DOI: 10.1073/Pnas.0509392103  0.354
2006 Kroon-Batenburg LMJ, Bouma B, Gebbink MFBG, Gros P. Formation of amyloid fibres followed by X-ray diffraction in real time. Implications for the identity of bio-active species in conformational diseases like Alzheimer's disease Acta Crystallographica Section a Foundations of Crystallography. 62: s38-s38. DOI: 10.1107/S0108767306099235  0.375
2005 Janssen BJ, Huizinga EG, Raaijmakers HC, Roos A, Daha MR, Nilsson-Ekdahl K, Nilsson B, Gros P. Structures of complement component C3 provide insights into the function and evolution of immunity. Nature. 437: 505-11. PMID 16177781 DOI: 10.1038/Nature04005  0.759
2004 Scheres SH, Gros P. The potentials of conditional optimization in phasing and model building of protein crystal structures. Acta Crystallographica. Section D, Biological Crystallography. 60: 2202-9. PMID 15572773 DOI: 10.1107/S0907444904008996  0.591
2004 Oomen CJ, van Ulsen P, van Gelder P, Feijen M, Tommassen J, Gros P. Structure of the translocator domain of a bacterial autotransporter. The Embo Journal. 23: 1257-66. PMID 15014442 DOI: 10.1038/Sj.Emboj.7600148  0.333
2003 Dekker C, de Kruijff B, Gros P. Crystal structure of SecB from Escherichia coli. Journal of Structural Biology. 144: 313-9. PMID 14643199 DOI: 10.1016/J.Jsb.2003.09.012  0.428
2003 Vandeputte-Rutten L, Bos MP, Tommassen J, Gros P. Crystal structure of Neisserial surface protein A (NspA), a conserved outer membrane protein with vaccine potential. The Journal of Biological Chemistry. 278: 24825-30. PMID 12716881 DOI: 10.1074/Jbc.M302803200  0.38
2003 Scheres SH, Gros P. Development of a force field for conditional optimization of protein structures. Acta Crystallographica. Section D, Biological Crystallography. 59: 438-46. PMID 12595700 DOI: 10.1107/S0907444902022850  0.595
2003 Agianian B, Tucker PA, Schouten A, Leonard K, Bullard B, Gros P. Structure of a Drosophila sigma class glutathione S-transferase reveals a novel active site topography suited for lipid peroxidation products. Journal of Molecular Biology. 326: 151-65. PMID 12547198 DOI: 10.1016/S0022-2836(02)01327-X  0.365
2002 Vandeputte-Rutten L, Gros P. Novel proteases: common themes and surprising features. Current Opinion in Structural Biology. 12: 704-8. PMID 12504673 DOI: 10.1016/S0959-440X(02)00393-7  0.341
2002 Weik M, Bergès J, Raves ML, Gros P, McSweeney S, Silman I, Sussman JL, Houée-Levin C, Ravelli RB. Evidence for the formation of disulfide radicals in protein crystals upon X-ray irradiation. Journal of Synchrotron Radiation. 9: 342-6. PMID 12409620 DOI: 10.1107/S0909049502014589  0.303
2002 van Tiel CM, Schouten A, Snoek GT, Gros P, Wirtz KW. The structure of phosphatidylinositol transfer protein alpha reveals sites for phospholipid binding and membrane association with major implications for its function. Febs Letters. 531: 69-73. PMID 12401206 DOI: 10.1016/S0014-5793(02)03403-8  0.353
2002 Huizinga EG, Tsuji S, Romijn RA, Schiphorst ME, de Groot PG, Sixma JJ, Gros P. Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain. Science (New York, N.Y.). 297: 1176-9. PMID 12183630 DOI: 10.1126/Science.107355  0.366
2002 Schouten A, Agianian B, Westerman J, Kroon J, Wirtz KW, Gros P. Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association. The Embo Journal. 21: 2117-21. PMID 11980708 DOI: 10.1093/Emboj/21.9.2117  0.345
2002 Kramer RA, Brandenburg K, Vandeputte-Rutten L, Werkhoven M, Gros P, Dekker N, Egmond MR. Lipopolysaccharide regions involved in the activation of Escherichia coli outer membrane protease OmpT. European Journal of Biochemistry / Febs. 269: 1746-52. PMID 11895445 DOI: 10.1046/J.1432-1327.2002.02820.X  0.303
2002 Huizinga EG, Tsuji S, Romijn RAP, Schiphorst ME, de Groot PG, Sixma JJ, Gros P. Structures of platelet-receptor glycoprotein Ib and its complex with von Willebrand factor domain A1 Acta Crystallographica Section a Foundations of Crystallography. 58: c238-c238. DOI: 10.1107/S0108767302094539  0.336
2001 Kramer RA, Vandeputte-Rutten L, Roon GJd, Gros P, Dekker N, Egmond MR. Identification of essential acidic residues of outer membrane protease OmpT supports a novel active site Febs Letters. 505: 426-430. PMID 11576541 DOI: 10.1016/S0014-5793(01)02863-0  0.345
2001 Vandeputte-Rutten L, Kramer RA, Kroon J, Dekker N, Egmond MR, Gros P. Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site. The Embo Journal. 20: 5033-9. PMID 11566868 DOI: 10.1093/Emboj/20.18.5033  0.393
2001 Huizinga EG, Schouten A, Connolly TM, Kroon J, Sixma JJ, Gros P. The structure of leech anti-platelet protein, an inhibitor of haemostasis. Acta Crystallographica. Section D, Biological Crystallography. 57: 1071-8. PMID 11468390 DOI: 10.1107/S0907444901007405  0.432
2001 Agianian B, Clayton JD, Leonard K, Tucker P, Bullard B, Gros P. Crystallization and preliminary x-ray analysis of drosophila glutathione S-transferase-2 Acta Crystallographica Section D: Biological Crystallography. 57: 725-727. PMID 11320318 DOI: 10.1107/S0907444901003110  0.34
2001 Romijn RA, Bouma B, Wuyster W, Gros P, Kroon J, Sixma JJ, Huizinga EG. Identification of the collagen-binding site of the von Willebrand factor A3-domain. The Journal of Biological Chemistry. 276: 9985-91. PMID 11098050 DOI: 10.1074/Jbc.M006548200  0.373
2001 de Groot G PG, Bouma B, Lutters BC, Simmelink MJ, Derksen RH, Gros P. Structure-function studies on beta 2-glycoprotein I. Journal of Autoimmunity. 15: 87-9. PMID 10968890 DOI: 10.1006/Jaut.2000.0394  0.308
2000 Weik M, Ravelli RBG, Kryger G, McSweeney S, Raves ML, Harel M, Gros P, Silman I, Kroon J, Sussman JL. Specific chemical and structural damage to proteins produced by synchrotron radiation Proceedings of the National Academy of Sciences of the United States of America. 97: 623-628. PMID 10639129 DOI: 10.1073/Pnas.97.2.623  0.31
2000 Scheres SHW, van den Elsen JMH, Meisterernst M, Kroon J, Gros P. Structural studies of the transcription cofactor PC4 Acta Crystallographica Section a Foundations of Crystallography. 56: s274-s274. DOI: 10.1107/S010876730002585X  0.327
1999 Dekker C, de Kruijff B, de Korte-Kool G, Kroon J, Gros P. Crystals of acetylated SecB diffract to 2.3-A resolution. Journal of Structural Biology. 128: 237-42. PMID 10633062 DOI: 10.1006/Jsbi.1999.4179  0.324
1999 Bouma B, de Groot PG, van den Elsen JM, Ravelli RB, Schouten A, Simmelink MJ, Derksen RH, Kroon J, Gros P. Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure. The Embo Journal. 18: 5166-74. PMID 10508150 DOI: 10.1093/Emboj/18.19.5166  0.385
1999 Elsen JMHvd, Vandeputte-Rutten L, Kroon J, Gros P. Bactericidal antibody recognition of meningococcal PorA by induced fit. Comparison of liganded and unliganded Fab structures. Journal of Biological Chemistry. 274: 1495-1501. PMID 9880525 DOI: 10.1074/Jbc.274.3.1495  0.409
1998 Werten S, Stelzer G, Goppelt A, Langen FM, Gros P, Timmers HT, Van der Vliet PC, Meisterernst M. Interaction of PC4 with melted DNA inhibits transcription. The Embo Journal. 17: 5103-11. PMID 9724646 DOI: 10.1093/Emboj/17.17.5103  0.307
1997 Brandsen J, Werten S, van der Vliet PC, Meisterernst M, Kroon J, Gros P. C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site. Nature Structural Biology. 4: 900-3. PMID 9360603 DOI: 10.1038/Nsb1197-900  0.375
1997 Huizinga EG, Martijn van der Plas R, Kroon J, Sixma JJ, Gros P. Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding. Structure (London, England : 1993). 5: 1147-56. PMID 9331419 DOI: 10.1016/S0969-2126(97)00266-9  0.341
1997 van den Elsen JM, Herron JN, Hoogerhout P, Poolman JT, Boel E, Logtenberg T, Wilting J, Crommelin DJ, Kroon J, Gros P. Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide. Proteins. 29: 113-25. PMID 9294871 DOI: 10.1002/(Sici)1097-0134(199709)29:1<113::Aid-Prot9>3.0.Co;2-G  0.357
1996 Teplyakov A, Gros P, Hol WG. Crystallographic study of eglin-C binding to thermitase. Advances in Experimental Medicine and Biology. 379: 5-9. PMID 8796305 DOI: 10.1007/978-1-4613-0319-0_2  0.586
1994 van Gunsteren WF, Brunne RM, Gros P, van Schaik RC, Schiffer CA, Torda AE. Accounting for molecular mobility in structure determination based on nuclear magnetic resonance spectroscopic and X-ray diffraction data. Methods in Enzymology. 239: 619-54. PMID 7530320 DOI: 10.1016/S0076-6879(94)39024-X  0.303
1992 Gros P, Teplyakov AV, Hol WG. Effects of eglin-c binding to thermitase: three-dimensional structure comparison of native thermitase and thermitase eglin-c complexes. Proteins. 12: 63-74. PMID 1553381 DOI: 10.1002/Prot.340120108  0.607
1991 Gros P, Kalk KH, Hol WG. Calcium binding to thermitase. Crystallographic studies of thermitase at 0, 5, and 100 mM calcium. The Journal of Biological Chemistry. 266: 2953-61. PMID 1993669 DOI: 10.2210/Pdb3Tec/Pdb  0.536
1990 Gros P, van Gunsteren WF, Hol WG. Inclusion of thermal motion in crystallographic structures by restrained molecular dynamics. Science (New York, N.Y.). 249: 1149-52. PMID 2396108 DOI: 10.1126/Science.2396108  0.54
1989 Gros P, Betzel C, Dauter Z, Wilson KS, Hol WG. Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content. Journal of Molecular Biology. 210: 347-67. PMID 2689655 DOI: 10.1016/0022-2836(89)90336-7  0.592
1989 Gros P, Fujinaga M, Dijkstra BW, Kalk KH, Hol WG. Crystallographic refinement by incorporation of molecular dynamics: thermostable serine protease thermitase complexed with eglin c. Acta Crystallographica. Section B, Structural Science. 45: 488-99. PMID 2688688 DOI: 10.1107/S0108768189006038  0.551
1989 Fujinaga M, Gros P, van Gunsteren WF. Testing the method of crystallographic refinement using molecular dynamics Journal of Applied Crystallography. 22: 1-8. DOI: 10.1107/S0021889888009550  0.325
1988 Gros P, Groendijk H, Drenth J, Hol WGJ. Experiments in membrane protein crystallization Journal of Crystal Growth. 90: 193-200. DOI: 10.1016/0022-0248(88)90315-6  0.559
1987 Kelders HA, Kalk KH, Gros P, Hol WG. Automated protein crystallization and a new crystal form of a subtilisin:eglin complex. Protein Engineering. 1: 301-3. PMID 3334088 DOI: 10.1093/Protein/1.4.301  0.536
Show low-probability matches.