Piet Gros - Publications

Utrecht University, Utrecht, Netherlands 

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G, Holers VM, Huber-Lang M, Kinoshita T, Mollnes TE, Montgomery RA, Morgan BP, Nilsson B, et al. Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development. Nature Immunology. PMID 31605100 DOI: 10.1038/s41590-019-0531-x  0.36
2019 Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G, Holers VM, Huber-Lang M, Kinoshita T, Mollnes TE, Montgomery RA, Morgan BP, Nilsson B, et al. 'Stealth' corporate innovation: an emerging threat for therapeutic drug development. Nature Immunology. PMID 31562490 DOI: 10.1038/s41590-019-0503-1  0.36
2019 van den Bos RM, Pearce NM, Granneman J, Brondijk THC, Gros P. Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b. Frontiers in Immunology. 10: 2097. PMID 31552043 DOI: 10.3389/fimmu.2019.02097  0.4
2019 Sharp TH, Boyle AL, Diebolder CA, Kros A, Koster AJ, Gros P. Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b. Proceedings of the National Academy of Sciences of the United States of America. PMID 31147461 DOI: 10.1073/pnas.1901841116  0.36
2018 Oosterheert W, van Bezouwen LS, Rodenburg RNP, Granneman J, Förster F, Mattevi A, Gros P. Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction. Nature Communications. 9: 4337. PMID 30337524 DOI: 10.1038/s41467-018-06817-7  0.4
2018 Ugurlar D, Howes SC, de Kreuk BJ, Koning RI, de Jong RN, Beurskens FJ, Schuurman J, Koster AJ, Sharp TH, Parren PWHI, Gros P. Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement. Science (New York, N.Y.). 359: 794-797. PMID 29449492 DOI: 10.1126/science.aao4988  0.36
2017 Rodenburg RNP, Snijder J, van de Waterbeemd M, Schouten A, Granneman J, Heck AJR, Gros P. Stochastic palmitoylation of accessible cysteines in membrane proteins revealed by native mass spectrometry. Nature Communications. 8: 1280. PMID 29097667 DOI: 10.1038/s41467-017-01461-z  0.4
2017 Xue X, Wu J, Ricklin D, Forneris F, Di Crescenzio P, Schmidt CQ, Granneman J, Sharp TH, Lambris JD, Gros P. Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses. Nature Structural & Molecular Biology. PMID 28671664 DOI: 10.1038/nsmb.3427  1
2016 De Nardis C, Lössl P, van den Biggelaar M, Madoori PK, Leloup N, Mertens K, Heck AJ, Gros P. Recombinant Expression of the Full-length Ectodomain of LDL Receptor-related Protein 1 (LRP1) Unravels pH-dependent Conformational Changes and the Stoichiometry of Binding with Receptor-associated Protein (RAP). The Journal of Biological Chemistry. PMID 27956551 DOI: 10.1074/jbc.M116.758862  0.36
2016 Ricklin D, Reis ES, Mastellos DC, Gros P, Lambris JD. Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense. Immunological Reviews. 274: 33-58. PMID 27782325 DOI: 10.1111/imr.12500  0.36
2016 Sharp TH, G A Faas F, Koster AJ, Gros P. Imaging complement by phase-plate cryo-electron tomography from initiation to pore formation. Journal of Structural Biology. PMID 27663685 DOI: 10.1016/j.jsb.2016.09.008  0.36
2016 Sharp TH, Koster AJ, Gros P. Heterogeneous MAC Initiator and Pore Structures in a Lipid Bilayer by Phase-Plate Cryo-electron Tomography. Cell Reports. 15: 1-8. PMID 27052168 DOI: 10.1016/j.celrep.2016.03.002  0.36
2016 Forneris F, Wu J, Xue X, Ricklin D, Lin Z, Sfyroera G, Tzekou A, Volokhina E, Granneman JC, Hauhart R, Bertram P, Liszewski MK, Atkinson JP, Lambris JD, Gros P. Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode. The Embo Journal. PMID 27013439 DOI: 10.15252/embj.201593673  1
2014 Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster AJ, Taylor RP, Saphire EO, ... ... Gros P, et al. Complement is activated by IgG hexamers assembled at the cell surface. Science (New York, N.Y.). 343: 1260-3. PMID 24626930 DOI: 10.1126/science.1248943  1
2014 Forneris F, Burnley BT, Gros P. Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D. Acta Crystallographica. Section D, Biological Crystallography. 70: 733-43. PMID 24598742 DOI: 10.1107/S1399004713032549  1
2014 de Lau W, Peng WC, Gros P, Clevers H. The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength. Genes & Development. 28: 305-16. PMID 24532711 DOI: 10.1101/gad.235473.113  1
2013 Peng WC, de Lau W, Madoori PK, Forneris F, Granneman JC, Clevers H, Gros P. Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling. Plos One. 8: e83110. PMID 24349440 DOI: 10.1371/journal.pone.0083110  1
2013 Peng WC, de Lau W, Forneris F, Granneman JC, Huch M, Clevers H, Gros P. Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5. Cell Reports. 3: 1885-92. PMID 23809763 DOI: 10.1016/j.celrep.2013.06.009  1
2013 Forneris F, Gros P. Complement Factor D Handbook of Proteolytic Enzymes. 3: 2841-2848. DOI: 10.1016/B978-0-12-382219-2.00630-X  1
2013 Gros P, Forneris F. Proteolysis, complex formation and conformational changes drive the complement pathways Nato Science For Peace and Security Series a: Chemistry and Biology. 297-307. DOI: 10.1007/978-94-007-6232-9-25  1
2012 Burnley BT, Afonine PV, Adams PD, Gros P. Modelling dynamics in protein crystal structures by ensemble refinement. Elife. 1: e00311. PMID 23251785 DOI: 10.7554/eLife.00311  1
2012 Hadders MA, Bubeck D, Roversi P, Hakobyan S, Forneris F, Morgan BP, Pangburn MK, Llorca O, Lea SM, Gros P. Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9. Cell Reports. 1: 200-7. PMID 22832194 DOI: 10.1016/j.celrep.2012.02.003  1
2012 Volokhina E, Westra D, Xue X, Gros P, van de Kar N, van den Heuvel L. Novel C3 mutation p.Lys65Gln in aHUS affects complement factor H binding. Pediatric Nephrology (Berlin, Germany). 27: 1519-24. PMID 22669319 DOI: 10.1007/s00467-012-2183-z  1
2012 van Galen J, Olrichs NK, Schouten A, Serrano RL, Nolte-'t Hoen EN, Eerland R, Kaloyanova D, Gros P, Helms JB. Interaction of GAPR-1 with lipid bilayers is regulated by alternative homodimerization. Biochimica Et Biophysica Acta. 1818: 2175-83. PMID 22560898 DOI: 10.1016/j.bbamem.2012.04.016  1
2012 Forneris F, Wu J, Gros P. The modular serine proteases of the complement cascade. Current Opinion in Structural Biology. 22: 333-41. PMID 22560446 DOI: 10.1016/j.sbi.2012.04.001  1
2011 Gros P. In self-defense. Nature Structural & Molecular Biology. 18: 401-2. PMID 21336275 DOI: 10.1038/nsmb.2036  1
2010 Forneris F, Ricklin D, Wu J, Tzekou A, Wallace RS, Lambris JD, Gros P. Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science (New York, N.Y.). 330: 1816-20. PMID 21205667 DOI: 10.1126/science.1195821  1
2009 Janssen BJ, Gomes L, Koning RI, Svergun DI, Koster AJ, Fritzinger DC, Vogel CW, Gros P. Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex. The Embo Journal. 28: 2469-78. PMID 19574954 DOI: 10.1038/emboj.2009.184  0.36
2009 Wu J, Wu YQ, Ricklin D, Janssen BJ, Lambris JD, Gros P. Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nature Immunology. 10: 728-33. PMID 19503104 DOI: 10.1038/ni.1755  0.48
2009 Rooijakkers SH, Wu J, Ruyken M, van Domselaar R, Planken KL, Tzekou A, Ricklin D, Lambris JD, Janssen BJ, van Strijp JA, Gros P. Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor. Nature Immunology. 10: 721-7. PMID 19503103 DOI: 10.1038/ni.1756  0.48
2009 Rutten L, Wieczorek B, Mannie JP, Kruithof CA, Dijkstra HP, Egmond MR, Lutz M, Klein Gebbink RJ, Gros P, van Koten G. Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 4270-80. PMID 19219875 DOI: 10.1002/chem.200801995  1
2009 Rutten L, Mannie JP, Stead CM, Raetz CR, Reynolds CM, Bonvin AM, Tommassen JP, Egmond MR, Trent MS, Gros P. Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium. Proceedings of the National Academy of Sciences of the United States of America. 106: 1960-4. PMID 19174515 DOI: 10.1073/pnas.0813064106  1
2009 Fritzinger DC, Hew BE, Thorne M, Pangburn MK, Janssen BJ, Gros P, Vogel CW. Functional characterization of human C3/cobra venom factor hybrid proteins for therapeutic complement depletion. Developmental and Comparative Immunology. 33: 105-16. PMID 18760301 DOI: 10.1016/j.dci.2008.07.006  0.36
2008 Gros P, Milder FJ, Janssen BJ. Complement driven by conformational changes. Nature Reviews. Immunology. 8: 48-58. PMID 18064050 DOI: 10.1038/nri2231  0.36
2007 Rooijakkers SH, Milder FJ, Bardoel BW, Ruyken M, van Strijp JA, Gros P. Staphylococcal complement inhibitor: structure and active sites. Journal of Immunology (Baltimore, Md. : 1950). 179: 2989-98. PMID 17709514  0.36
2007 Janssen BJ, Read RJ, Brünger AT, Gros P. Crystallography: crystallographic evidence for deviating C3b structure. Nature. 448: E1-2; discussion E2-. PMID 17687277 DOI: 10.1038/nature06102  1
2007 Janssen BJ, Halff EF, Lambris JD, Gros P. Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition. The Journal of Biological Chemistry. 282: 29241-7. PMID 17684013 DOI: 10.1074/jbc.M704587200  0.36
2007 Milder FJ, Gomes L, Schouten A, Janssen BJ, Huizinga EG, Romijn RA, Hemrika W, Roos A, Daha MR, Gros P. Factor B structure provides insights into activation of the central protease of the complement system. Nature Structural & Molecular Biology. 14: 224-8. PMID 17310251 DOI: 10.1038/nsmb1210  1
2007 Janssen BJ, Gros P. Structural insights into the central complement component C3. Molecular Immunology. 44: 3-10. PMID 16875735 DOI: 10.1016/j.molimm.2006.06.017  1
2006 Janssen BJ, Christodoulidou A, McCarthy A, Lambris JD, Gros P. Structure of C3b reveals conformational changes that underlie complement activity. Nature. 444: 213-6. PMID 17051160 DOI: 10.1038/nature05172  0.36
2006 Milder FJ, Raaijmakers HC, Vandeputte MD, Schouten A, Huizinga EG, Romijn RA, Hemrika W, Roos A, Daha MR, Gros P. Structure of complement component C2A: implications for convertase formation and substrate binding. Structure (London, England : 1993). 14: 1587-97. PMID 17027507 DOI: 10.1016/j.str.2006.08.008  1
2006 Janssen BJ, Gros P. Conformational complexity of complement component C3. Advances in Experimental Medicine and Biology. 586: 291-312. PMID 16893080 DOI: 10.1007/0-387-34134-X_20  1
2006 Brown KM, Kondeatis E, Vaughan RW, Kon SP, Farmer CKT, Taylor JD, He X, Johnston A, Horsfield C, Janssen BJC, Gros P, Zhou W, Sacks SH, Sheerin NS. Influence of donor C3 allotype on late renal-transplantation outcome New England Journal of Medicine. 354: 2014-2023. PMID 16687714  1
2006 Rutten L, Geurtsen J, Lambert W, Smolenaers JJ, Bonvin AM, de Haan A, van der Ley P, Egmond MR, Gros P, Tommassen J. Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. 103: 7071-6. PMID 16632613 DOI: 10.1073/pnas.0509392103  1
2005 Janssen BJ, Huizinga EG, Raaijmakers HC, Roos A, Daha MR, Nilsson-Ekdahl K, Nilsson B, Gros P. Structures of complement component C3 provide insights into the function and evolution of immunity. Nature. 437: 505-11. PMID 16177781 DOI: 10.1038/nature04005  1
2004 Scheres SH, Gros P. The potentials of conditional optimization in phasing and model building of protein crystal structures. Acta Crystallographica. Section D, Biological Crystallography. 60: 2202-9. PMID 15572773 DOI: 10.1107/S0907444904008996  1
2003 Dekker C, de Kruijff B, Gros P. Crystal structure of SecB from Escherichia coli. Journal of Structural Biology. 144: 313-9. PMID 14643199 DOI: 10.1016/j.jsb.2003.09.012  1
2003 Scheres SH, Gros P. Development of a force field for conditional optimization of protein structures. Acta Crystallographica. Section D, Biological Crystallography. 59: 438-46. PMID 12595700 DOI: 10.1107/S0907444902022850  1
2003 Agianian B, Tucker PA, Schouten A, Leonard K, Bullard B, Gros P. Structure of a Drosophila sigma class glutathione S-transferase reveals a novel active site topography suited for lipid peroxidation products. Journal of Molecular Biology. 326: 151-65. PMID 12547198 DOI: 10.1016/S0022-2836(02)01327-X  1
2002 Vandeputte-Rutten L, Gros P. Novel proteases: common themes and surprising features. Current Opinion in Structural Biology. 12: 704-8. PMID 12504673 DOI: 10.1016/S0959-440X(02)00393-7  1
2002 Weik M, Bergès J, Raves ML, Gros P, McSweeney S, Silman I, Sussman JL, Houée-Levin C, Ravelli RB. Evidence for the formation of disulfide radicals in protein crystals upon X-ray irradiation. Journal of Synchrotron Radiation. 9: 342-6. PMID 12409620 DOI: 10.1107/S0909049502014589  1
2002 Kramer RA, Brandenburg K, Vandeputte-Rutten L, Werkhoven M, Gros P, Dekker N, Egmond MR. Lipopolysaccharide regions involved in the activation of Escherichia coli outer membrane protease OmpT. European Journal of Biochemistry / Febs. 269: 1746-52. PMID 11895445 DOI: 10.1046/j.1432-1327.2002.02820.x  1
1996 Teplyakov A, Gros P, Hol WG. Crystallographic study of eglin-C binding to thermitase. Advances in Experimental Medicine and Biology. 379: 5-9. PMID 8796305  1
1992 Gros P, Teplyakov AV, Hol WG. Effects of eglin-c binding to thermitase: three-dimensional structure comparison of native thermitase and thermitase eglin-c complexes. Proteins. 12: 63-74. PMID 1553381 DOI: 10.1002/prot.340120108  1
1991 Gros P, Kalk KH, Hol WG. Calcium binding to thermitase. Crystallographic studies of thermitase at 0, 5, and 100 mM calcium. The Journal of Biological Chemistry. 266: 2953-61. PMID 1993669  0.8
1990 Gros P, van Gunsteren WF, Hol WG. Inclusion of thermal motion in crystallographic structures by restrained molecular dynamics. Science (New York, N.Y.). 249: 1149-52. PMID 2396108  0.8
1989 Gros P, Betzel C, Dauter Z, Wilson KS, Hol WG. Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content. Journal of Molecular Biology. 210: 347-67. PMID 2689655  0.8
1989 Gros P, Fujinaga M, Dijkstra BW, Kalk KH, Hol WG. Crystallographic refinement by incorporation of molecular dynamics: thermostable serine protease thermitase complexed with eglin c. Acta Crystallographica. Section B, Structural Science. 45: 488-99. PMID 2688688  0.8
1987 Kelders HA, Kalk KH, Gros P, Hol WG. Automated protein crystallization and a new crystal form of a subtilisin:eglin complex. Protein Engineering. 1: 301-3. PMID 3334088  0.8
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