Year |
Citation |
Score |
2024 |
Gui F, Jiang B, Jiang J, He Z, Tsujino T, Takai T, Arai S, Pana C, Köllermann J, Bradshaw GA, Eisert R, Kalocsay M, Fassl A, Balk SP, Kibel AS, et al. Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer. Biorxiv : the Preprint Server For Biology. PMID 39026842 DOI: 10.1101/2024.07.09.602803 |
0.722 |
|
2024 |
Ji W, Du G, Jiang J, Lu W, Mills CE, Yuan L, Jiang F, He Z, Bradshaw GA, Chung M, Jiang Z, Byun WS, Hinshaw SM, Zhang T, Gray NS. Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7). European Journal of Medicinal Chemistry. 276: 116613. PMID 39004018 DOI: 10.1016/j.ejmech.2024.116613 |
0.634 |
|
2024 |
Liu HY, Li Z, Reindl T, He Z, Qiu X, Golden RP, Donovan KA, Bailey A, Fischer ES, Zhang T, Gray NS, Yang PL. Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism. Nature Communications. 15: 5179. PMID 38898037 DOI: 10.1038/s41467-024-49161-9 |
0.441 |
|
2024 |
Li Z, Liu HY, He Z, Chakravarty A, Golden RP, Jiang Z, You I, Yue H, Donovan KA, Du G, Che J, Tse J, Che I, Lu W, Fischer ES, et al. Discovery of Potent Degraders of the Dengue Virus Envelope Protein. Biorxiv : the Preprint Server For Biology. PMID 38854003 DOI: 10.1101/2024.06.01.596987 |
0.423 |
|
2023 |
Arwood ML, Liu Y, Harkins SK, Weinstock DM, Yang L, Stevenson KE, Plana OD, Dong J, Cirka H, Jones KL, Virtanen AT, Gupta DG, Ceas A, Lawney B, Yoda A, ... ... He Z, et al. New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation. Cell Chemical Biology. PMID 37290440 DOI: 10.1016/j.chembiol.2023.05.007 |
0.477 |
|
2023 |
Lu W, Liu Y, Gao Y, Geng Q, Gurbani D, Li L, Ficarro SB, Meyer CJ, Sinha D, You I, Tse J, He Z, Ji W, Che J, Kim AY, et al. Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of Medicinal Chemistry. 66: 3356-3371. PMID 36826833 DOI: 10.1021/acs.jmedchem.2c01834 |
0.51 |
|
2022 |
Fan M, Lu W, Che J, Kwiatkowski NP, Gao Y, Seo HS, Ficarro SB, Gokhale PC, Liu Y, Geffken EA, Lakhani J, Song K, Kuljanin M, Ji W, Jiang J, ... He Z, et al. Covalent disruptor of YAP-TEAD association suppresses defective hippo signaling. Elife. 11. PMID 36300789 DOI: 10.7554/eLife.78810 |
0.612 |
|
2022 |
Du G, Jiang J, Henning NJ, Safaee N, Koide E, Nowak RP, Donovan KA, Yoon H, You I, Yue H, Eleuteri NA, He Z, Li Z, Huang HT, Che J, et al. Exploring the target scope of KEAP1 E3 ligase-based PROTACs. Cell Chemical Biology. PMID 36070758 DOI: 10.1016/j.chembiol.2022.08.003 |
0.526 |
|
2021 |
Powell CE, Du G, Bushman JW, He Z, Zhang T, Fischer ES, Gray NS. Selective degradation-inducing probes for studying cereblon (CRBN) biology. Rsc Medicinal Chemistry. 12: 1381-1390. PMID 34458741 DOI: 10.1039/d0md00382d |
0.475 |
|
2020 |
Jiang J, Jiang B, He Z, Ficarro SB, Che J, Marto JA, Gao Y, Zhang T, Gray NS. Discovery of Covalent MKK4/7 Dual Inhibitor. Cell Chemical Biology. PMID 32916088 DOI: 10.1016/J.Chembiol.2020.08.014 |
0.676 |
|
2020 |
Powell CE, Du G, Che J, He Z, Donovan KA, Yue H, Wang ES, Nowak RP, Zhang T, Fischer ES, Gray NS. Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. Acs Chemical Biology. PMID 32865967 DOI: 10.1021/Acschembio.0C00520 |
0.518 |
|
2020 |
Liu Y, Hao M, Leggett A, Gao Y, Ficarro SB, Che J, He Z, Olson C, Marto JA, Kwiatkowski N, Zhang T, Gray NS. Discovery of MFH290: A Potent and Highly Selective Covalent Inhibitor for Cyclin-Dependent Kinase 12/13. Journal of Medicinal Chemistry. PMID 32502343 DOI: 10.1021/Acs.Jmedchem.9B01929 |
0.504 |
|
2020 |
Gray NS, Teng M, Jiang J, He Z, Kwiatkowski NP, Donovan KA, Mills CE, Victor C, Hatcher JM, Fischer ES, Sorger PK, Zhang T. Development of CDK2 and CDK5 Dual Degrader TMX-2172. Angewandte Chemie (International Ed. in English). PMID 32415712 DOI: 10.1002/Anie.202004087 |
0.632 |
|
2020 |
Liu J, Chen H, Ma L, He Z, Wang D, Liu Y, Lin Q, Zhang T, Gray N, Kaniskan HÜ, Jin J, Wei W. Light-induced control of protein destruction by opto-PROTAC. Science Advances. 6: eaay5154. PMID 32128407 DOI: 10.1126/Sciadv.Aay5154 |
0.486 |
|
2020 |
Xiao H, Jedrychowski MP, Schweppe DK, Huttlin EL, Yu Q, Heppner DE, Li J, Long J, Mills EL, Szpyt J, He Z, Du G, Garrity R, Reddy A, Vaites LP, et al. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. PMID 32109415 DOI: 10.1016/J.Cell.2020.02.012 |
0.43 |
|
2019 |
Zhang H, Christensen CL, Dries R, Oser MG, Deng J, Diskin B, Li F, Pan Y, Zhang X, Yin Y, Papadopoulos E, Pyon V, Thakurdin C, Kwiatkowski N, Jani K, ... ... He Z, et al. CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer. Cancer Cell. PMID 31883968 DOI: 10.1016/J.Ccell.2019.11.003 |
0.541 |
|
2019 |
Gui F, Jiang J, He Z, Li L, Li Y, Deng Z, Lu Y, Wu X, Chen G, Su J, Song S, Zhang YM, Yun CH, Huang X, Weisberg E, et al. A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant Btk mutation in B-cell malignancies. British Journal of Pharmacology. PMID 31364164 DOI: 10.1111/Bph.14809 |
0.751 |
|
2018 |
Nowak RP, DeAngelo SL, Buckley D, He Z, Donovan KA, An J, Safaee N, Jedrychowski MP, Ponthier CM, Ishoey M, Zhang T, Mancias JD, Gray NS, Bradner JE, Fischer ES. Plasticity in binding confers selectivity in ligand-induced protein degradation. Nature Chemical Biology. PMID 29892083 DOI: 10.1038/S41589-018-0055-Y |
0.452 |
|
2018 |
Huang W, Sun X, Li Y, He Z, Li L, Deng Z, Huang X, Han S, Zhang T, Zhong J, Wang Z, Xu Q, Zhang J, Deng X. Discovery and Identification of Small Molecules as Methuosis Inducers with In Vivo Antitumor Activities. Journal of Medicinal Chemistry. PMID 29878764 DOI: 10.1021/Acs.Jmedchem.8B00753 |
0.71 |
|
2016 |
Jiang J, Gui F, He Z, Li L, Li Y, Li S, Wu X, Deng Z, Sun X, Huang X, Huang W, Han S, Zhang T, Wang Z, Jiao B, et al. Targeting BRK-positive breast cancers with small molecule kinase inhibitors. Cancer Research. PMID 27758886 DOI: 10.1158/0008-5472.Can-16-1038 |
0.656 |
|
2016 |
Fan F, He Z, Kong LL, Chen Q, Yuan Q, Zhang S, Ye J, Liu H, Sun X, Geng J, Yuan L, Hong L, Xiao C, Zhang W, Sun X, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Science Translational Medicine. 8: 352ra108. PMID 27535619 DOI: 10.1126/Scitranslmed.Aaf2304 |
0.647 |
|
2015 |
Yao L, Huang L, He Z, Zhou C, Li G, Deng X. Phosphate enhances uptake of As species in garland chrysanthemum (C. coronarium) applied with chicken manure bearing roxarsone and its metabolites. Environmental Science and Pollution Research International. 22: 4654-9. PMID 25328095 DOI: 10.1007/s11356-014-3711-0 |
0.417 |
|
2014 |
Huang L, Yao L, He Z, Zhou C, Li G, Yang B, Deng X. Roxarsone and its metabolites in chicken manure significantly enhance the uptake of As species by vegetables. Chemosphere. 100: 57-62. PMID 24461427 DOI: 10.1016/j.chemosphere.2013.12.074 |
0.41 |
|
2013 |
Yao L, Huang L, He Z, Zhou C, Li G, Yang B, Deng X. External inorganic N source enhances the uptake of As species in garland chrysanthemum (C. coronarium) amended with chicken manure bearing roxarsone and its metabolites. Journal of Hazardous Materials. 254: 270-6. PMID 23632040 DOI: 10.1016/j.jhazmat.2013.03.048 |
0.411 |
|
2012 |
Yang DL, Yao J, Mei CS, Tong XH, Zeng LJ, Li Q, Xiao LT, Sun TP, Li J, Deng XW, Lee CM, Thomashow MF, Yang Y, He Z, He SY. Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 109: E1192-200. PMID 22529386 DOI: 10.1073/Pnas.1201616109 |
0.459 |
|
2010 |
Zhai YF, Su Q, Wu WJ, He ZT, Zhang ZY, An JS, Dong J, Deng X, Han CG, Yu JL, Li DW, Chen XL, An D. [Fast discrimination of varieties of transgene wheat based on biomimetic pattern recognition and near infrared spectra]. Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu. 30: 924-8. PMID 20545132 DOI: 10.3964/j.issn.1000-0593(2010)04-0924-05 |
0.402 |
|
2009 |
Qi ZY, Deng XW, Huang SM, Zhang L, He ZC, Li XA, Kwan I, Lerch M, Cutajar D, Metcalfe P, Rosenfeld A. In vivo verification of superficial dose for head and neck treatments using intensity-modulated techniques. Medical Physics. 36: 59-70. PMID 19235374 |
0.392 |
|
2005 |
Zhang S, Chen C, Li L, Meng L, Singh J, Jiang N, Deng XW, He ZH, Lemaux PG. Evolutionary expansion, gene structure, and expression of the rice wall-associated kinase gene family. Plant Physiology. 139: 1107-24. PMID 16286450 DOI: 10.1104/Pp.105.069005 |
0.448 |
|
2003 |
Wang Z, Li X, Shi S, Qi D, He Z, Xu W, Deng X. [A comparison study on the species diversity between the gap and non-gap in Jinyun Mountain]. Ying Yong Sheng Tai Xue Bao = the Journal of Applied Ecology / Zhongguo Sheng Tai Xue Xue Hui, Zhongguo Ke Xue Yuan Shenyang Ying Yong Sheng Tai Yan Jiu Suo Zhu Ban. 14: 7-10. PMID 12722429 |
0.391 |
|
2001 |
Ma SC, He ZD, Deng XL, But PP, Ooi VE, Xu HX, Lee SH, Lee SF. In vitro evaluation of secoiridoid glucosides from the fruits of Ligustrum lucidum as antiviral agents. Chemical & Pharmaceutical Bulletin. 49: 1471-3. PMID 11724241 DOI: 10.1248/Cpb.49.1471 |
0.42 |
|
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