| Year |
Citation |
Score |
| 2023 |
Burrow NK, Gourdie RK, King EA, Travis CR, Goff CM, Nimmo ZM, Berg JM, Boyt EL, Young DD. Development of Multivalent Conjugates with a Single Non-Canonical Amino Acid. Chembiochem : a European Journal of Chemical Biology. e202300565. PMID 37737964 DOI: 10.1002/cbic.202300565 |
0.357 |
|
| 2023 |
Switzer HJ, Howard CA, Halonski JF, Peairs EM, Smith N, Zamecnik MP, Verma S, Young DD. Employing non-canonical amino acids towards the immobilization of a hyperthermophilic enzyme to increase protein stability. Rsc Advances. 13: 8496-8501. PMID 36926306 DOI: 10.1039/d3ra00392b |
0.786 |
|
| 2022 |
Williard AC, Switzer HJ, Howard CA, Yin R, Russell BL, Sanyal R, Yu S, Myers TM, Flood BM, Kerscher O, Young DD. Protein Modification Employing Non-Canonical Amino Acids to Prepare SUMOylation Detecting Bioconjugates. Pharmaceutics. 14. PMID 36559319 DOI: 10.3390/pharmaceutics14122826 |
0.704 |
|
| 2022 |
Hale EA, Ryan HM, McOsker AM, Funk CM, Green LC, Mazur LE, Uthappa DM, Flood BM, Young DD, Hinkle RJ. Effects of Structural Variations on Antibacterial Properties for Conjugated Diynes Generated through Glaser Hay Couplings. Chemmedchem. PMID 36194525 DOI: 10.1002/cmdc.202200455 |
0.752 |
|
| 2021 |
King EA, Peairs EM, Uthappa DM, Villa JK, Goff CM, Burrow NK, Deitch RT, Martin AK, Young DD. Photoregulation of PRMT-1 Using a Photolabile Non-Canonical Amino Acid. Molecules (Basel, Switzerland). 26. PMID 34443661 DOI: 10.3390/molecules26165072 |
0.796 |
|
| 2020 |
Travis CR, King EA, Gaunt GH, Young DD. Cover Feature: Genetic Encoding of a Bioconjugation Handle for [2+2+2] Cycloaddition Reactions (ChemBioChem 3/2020) Chembiochem. 21: 280-280. DOI: 10.1002/CBIC.202000012 |
0.631 |
|
| 2019 |
Travis C, Gaunt G, King E, Young DD. Genetic encoding of a bioconjugation handle for [2+2+2] cycloaddition reactions. Chembiochem : a European Journal of Chemical Biology. PMID 31298807 DOI: 10.1002/cbic.201900391 |
0.349 |
|
| 2019 |
Travis CR, Mazur LE, Peairs EM, Gaunt GH, Young DD. Mechanistic investigation and further optimization of the aqueous Glaser-Hay bioconjugation. Organic & Biomolecular Chemistry. PMID 30869108 DOI: 10.1039/c9ob00327d |
0.655 |
|
| 2018 |
Young DD, Schultz PG. Playing with the molecules of life. Acs Chemical Biology. PMID 29345901 DOI: 10.1021/Acschembio.7B00974 |
0.375 |
|
| 2018 |
Chatkewitz LE, Halonski JF, Padilla MS, Young DD. Investigation of copper-free alkyne/azide 1,3-dipolar cycloadditions using microwave irradiation. Bioorganic & Medicinal Chemistry Letters. 28: 81-84. PMID 29248298 DOI: 10.1016/J.Bmcl.2017.12.007 |
0.794 |
|
| 2017 |
Nimmo ZM, Halonski JF, Chatkewitz LE, Young DD. Development of optimized conditions for Glaser-Hay bioconjugations. Bioorganic Chemistry. 76: 326-331. PMID 29227916 DOI: 10.1016/J.Bioorg.2017.11.020 |
0.762 |
|
| 2017 |
Villa JK, Tran HA, Vipani M, Gianturco S, Bhasin K, Russell BL, Harbron EJ, Young DD. Fluorescence Modulation of Green Fluorescent Protein Using Fluorinated Unnatural Amino Acids. Molecules (Basel, Switzerland). 22. PMID 28714902 DOI: 10.3390/Molecules22071194 |
0.79 |
|
| 2016 |
Padilla MS, Farley CA, Chatkewitz LE, Young DD. Synthesis and incorporation of a caged tyrosine amino acid possessing a bioorthogonal handle. Tetrahedron Letters. 57: 4709-4712. PMID 28533567 DOI: 10.1016/J.Tetlet.2016.09.033 |
0.797 |
|
| 2016 |
Lampkowski JS, Uthappa DM, Halonski JF, Maza JC, Young DD. Application of the Solid-Supported Glaser-Hay Reaction to Natural Product Synthesis. The Journal of Organic Chemistry. 81: 12520-12524. PMID 27978730 DOI: 10.1021/acs.joc.6b02407 |
0.785 |
|
| 2016 |
Maza JC, Howard CA, Vipani MA, Travis CR, Young DD. Utilization of alkyne bioconjugations to modulate protein function. Bioorganic & Medicinal Chemistry Letters. PMID 27894869 DOI: 10.1016/j.bmcl.2016.11.041 |
0.789 |
|
| 2015 |
Maza JC, Nimmo ZM, Young DD. Expanding the scope of alkyne-mediated bioconjugations utilizing unnatural amino acids. Chemical Communications (Cambridge, England). PMID 26499242 DOI: 10.1039/c5cc08287k |
0.794 |
|
| 2015 |
Lampkowski JS, Uthappa DM, Young DD. Site-specific incorporation of a fluorescent terphenyl unnatural amino acid. Bioorganic & Medicinal Chemistry Letters. 25: 5277-80. PMID 26421994 DOI: 10.1016/j.bmcl.2015.09.050 |
0.795 |
|
| 2015 |
Maza JC, McKenna JR, Raliski BK, Freedman MT, Young DD. Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations. Bioconjugate Chemistry. 26: 1884-9. PMID 26287719 DOI: 10.1021/acs.bioconjchem.5b00424 |
0.715 |
|
| 2015 |
Lampkowski JS, Villa JK, Young TS, Young DD. Development and Optimization of Glaser-Hay Bioconjugations. Angewandte Chemie (International Ed. in English). PMID 26088803 DOI: 10.1002/Anie.201502676 |
0.731 |
|
| 2015 |
Govan JM, Young DD, Lively MO, Deiters A. Optically Triggered Immune Response through Photocaged Oligonucleotides. Tetrahedron Letters. 56: 3639-3642. PMID 26034339 DOI: 10.1016/J.Tetlet.2015.01.165 |
0.692 |
|
| 2015 |
Lampkowski JS, Maza JC, Verma S, Young DD. Optimization of solid-supported Glaser-Hay reactions in the microwave. Molecules (Basel, Switzerland). 20: 5276-85. PMID 25812149 DOI: 10.3390/Molecules20045276 |
0.763 |
|
| 2015 |
Padilla MS, Young DD. Photosensitive GFP mutants containing an azobenzene unnatural amino acid. Bioorganic & Medicinal Chemistry Letters. 25: 470-3. PMID 25563892 DOI: 10.1016/j.bmcl.2014.12.035 |
0.773 |
|
| 2015 |
Lampkowski JS, Durham CE, Padilla MS, Young DD. Preparation of asymmetrical polyynes by a solid-supported Glaser-Hay reaction. Organic & Biomolecular Chemistry. 13: 424-7. PMID 25371282 DOI: 10.1039/c4ob02196g |
0.799 |
|
| 2014 |
Raliski BK, Howard CA, Young DD. Site-specific protein immobilization using unnatural amino acids. Bioconjugate Chemistry. 25: 1916-20. PMID 25340826 DOI: 10.1021/bc500443h |
0.72 |
|
| 2014 |
Rust HL, Subramanian V, West GM, Young DD, Schultz PG, Thompson PR. Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. Acs Chemical Biology. 9: 649-55. PMID 24358983 DOI: 10.1021/Cb400859Z |
0.706 |
|
| 2014 |
Tripp VT, Young DD. Discovery of small molecule modifiers of microRNAs for the treatment of HCV infection. Methods in Molecular Biology (Clifton, N.J.). 1103: 153-63. PMID 24318893 DOI: 10.1007/978-1-62703-730-3_12 |
0.611 |
|
| 2014 |
Tripp VT, McKenna JR, Young DD. Approaches to the modulation of miRNA maturation. Methods in Molecular Biology (Clifton, N.J.). 1095: 27-58. PMID 24166301 DOI: 10.1007/978-1-62703-703-7_3 |
0.603 |
|
| 2013 |
Tripp VT, Maza JC, Young DD. Development of rapid microwave-mediated and low-temperature bacterial transformations. Journal of Chemical Biology. 6: 135-40. PMID 24432129 DOI: 10.1007/s12154-013-0095-4 |
0.647 |
|
| 2013 |
Govan JM, Young DD, Lusic H, Liu Q, Lively MO, Deiters A. Optochemical control of RNA interference in mammalian cells. Nucleic Acids Research. 41: 10518-28. PMID 24021631 DOI: 10.1093/Nar/Gkt806 |
0.716 |
|
| 2011 |
Young DD, Jockush S, Turro NJ, Schultz PG. Synthetase polyspecificity as a tool to modulate protein function. Bioorganic & Medicinal Chemistry Letters. 21: 7502-4. PMID 22041062 DOI: 10.1016/J.Bmcl.2011.09.108 |
0.736 |
|
| 2011 |
Georgianna WE, Young DD. Development and utilization of non-coding RNA-small molecule interactions. Organic & Biomolecular Chemistry. 9: 7969-78. PMID 21993406 DOI: 10.1039/c1ob06324c |
0.624 |
|
| 2011 |
Minnihan EC, Young DD, Schultz PG, Stubbe J. Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase. Journal of the American Chemical Society. 133: 15942-5. PMID 21913683 DOI: 10.1021/Ja207719F |
0.661 |
|
| 2011 |
Young TS, Young DD, Ahmad I, Louis JM, Benkovic SJ, Schultz PG. Evolution of cyclic peptide protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 11052-6. PMID 21690365 DOI: 10.1073/Pnas.1108045108 |
0.771 |
|
| 2011 |
Dush MK, McIver AL, Parr MA, Young DD, Fisher J, Newman DR, Sannes PL, Hauck ML, Deiters A, Nascone-Yoder N. Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chemistry & Biology. 18: 252-63. PMID 21338922 DOI: 10.1016/J.Chembiol.2010.12.008 |
0.686 |
|
| 2011 |
Young DD, Young TS, Jahnz M, Ahmad I, Spraggon G, Schultz PG. An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity. Biochemistry. 50: 1894-900. PMID 21280675 DOI: 10.1021/Bi101929E |
0.778 |
|
| 2011 |
Karginov AV, Zou Y, Shirvanyants D, Kota P, Dokholyan NV, Young DD, Hahn KM, Deiters A. Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. Journal of the American Chemical Society. 133: 420-3. PMID 21162531 DOI: 10.1021/Ja109630V |
0.72 |
|
| 2011 |
Young DD, Deiters A. Chemo- and Regioselectivity Enhancement in Solid-Supported Reactions Solid-Phase Organic Synthesis: Concepts, Strategies, and Applications. 171-204. DOI: 10.1002/9781118141649.ch6 |
0.724 |
|
| 2010 |
Young DD, Connelly CM, Grohmann C, Deiters A. Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. Journal of the American Chemical Society. 132: 7976-81. PMID 20527935 DOI: 10.1021/Ja910275U |
0.688 |
|
| 2010 |
Young DD, Lively MO, Deiters A. Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. Journal of the American Chemical Society. 132: 6183-93. PMID 20392038 DOI: 10.1021/Ja100710J |
0.725 |
|
| 2010 |
Chou C, Young DD, Deiters A. Photocaged t7 RNA polymerase for the light activation of transcription and gene function in pro- and eukaryotic cells. Chembiochem : a European Journal of Chemical Biology. 11: 972-7. PMID 20301166 DOI: 10.1002/Cbic.201000041 |
0.714 |
|
| 2010 |
Wilkins BJ, Marionni S, Young DD, Liu J, Wang Y, Di Salvo ML, Deiters A, Cropp TA. Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise. Biochemistry. 49: 1557-9. PMID 20136096 DOI: 10.1021/Bi100013S |
0.751 |
|
| 2010 |
Nascone-Yoder NM, Dush M, McIver A, Parr M, Young D, Fisher J, Hauck M, Deiters A. Heterotaxin: A novel TGF-beta signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos Developmental Biology. 344: 526. DOI: 10.1016/J.Ydbio.2010.05.483 |
0.674 |
|
| 2009 |
Chou C, Young DD, Deiters A. A light-activated DNA polymerase. Angewandte Chemie (International Ed. in English). 48: 5950-3. PMID 19569148 DOI: 10.1002/Anie.200901115 |
0.695 |
|
| 2009 |
Young DD, Govan JM, Lively MO, Deiters A. Photochemical regulation of restriction endonuclease activity. Chembiochem : a European Journal of Chemical Biology. 10: 1612-6. PMID 19533711 DOI: 10.1002/Cbic.200900090 |
0.711 |
|
| 2009 |
Edwards WF, Young DD, Deiters A. The effect of microwave irradiation on DNA hybridization. Organic & Biomolecular Chemistry. 7: 2506-8. PMID 19503920 DOI: 10.1039/B903609A |
0.69 |
|
| 2009 |
Bereman MS, Young DD, Deiters A, Muddiman DC. Development of a robust and high throughput method for profiling N-linked glycans derived from plasma glycoproteins by NanoLC-FTICR mass spectrometry. Journal of Proteome Research. 8: 3764-70. PMID 19435342 DOI: 10.1021/Pr9002323 |
0.682 |
|
| 2009 |
Edwards WF, Young DD, Deiters A. Light-activated Cre recombinase as a tool for the spatial and temporal control of gene function in mammalian cells. Acs Chemical Biology. 4: 441-5. PMID 19413301 DOI: 10.1021/Cb900041S |
0.72 |
|
| 2009 |
Young DD, Lusic H, Lively MO, Deiters A. Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization. Nucleic Acids Research. 37: e58. PMID 19293272 DOI: 10.1093/Nar/Gkp150 |
0.718 |
|
| 2009 |
Young DD, Garner RA, Yoder JA, Deiters A. Light-activation of gene function in mammalian cells via ribozymes. Chemical Communications (Cambridge, England). 568-70. PMID 19283293 DOI: 10.1039/B819375D |
0.699 |
|
| 2009 |
Young DD, Teske JA, Deiters A. Open-vessel microwave-mediated [2+2+2]-cyclotrimerization reactions Synthesis. 3785-3790. DOI: 10.1055/S-0029-1218149 |
0.72 |
|
| 2008 |
Young DD, Lusic H, Lively MO, Yoder JA, Deiters A. Gene silencing in mammalian cells with light-activated antisense agents. Chembiochem : a European Journal of Chemical Biology. 9: 2937-40. PMID 19021142 DOI: 10.1002/Cbic.200800627 |
0.701 |
|
| 2008 |
McIver A, Young DD, Deiters A. A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine. Chemical Communications (Cambridge, England). 4750-2. PMID 18830481 DOI: 10.1039/B811068A |
0.718 |
|
| 2008 |
Zou Y, Young DD, Cruz-Montanez A, Deiters A. Synthesis of anthracene and azaanthracene fluorophores via [2+2+2] cyclotrimerization reactions. Organic Letters. 10: 4661-4. PMID 18816125 DOI: 10.1021/Ol8019549 |
0.732 |
|
| 2008 |
Young DD, Torres-Kolbus J, Deiters A. Microwave-assisted synthesis of unnatural amino acids. Bioorganic & Medicinal Chemistry Letters. 18: 5478-80. PMID 18809329 DOI: 10.1016/J.Bmcl.2008.09.025 |
0.746 |
|
| 2008 |
Gumireddy K, Young DD, Xiong X, Hogenesch JB, Huang Q, Deiters A. Small-molecule inhibitors of microrna miR-21 function. Angewandte Chemie (International Ed. in English). 47: 7482-4. PMID 18712719 DOI: 10.1002/Anie.200801555 |
0.755 |
|
| 2008 |
Young DD, Nichols J, Kelly RM, Deiters A. Microwave activation of enzymatic catalysis. Journal of the American Chemical Society. 130: 10048-9. PMID 18613673 DOI: 10.1021/Ja802404G |
0.702 |
|
| 2008 |
Young DD, Deiters A. Light-regulated RNA-small molecule interactions. Chembiochem : a European Journal of Chemical Biology. 9: 1225-8. PMID 18404761 DOI: 10.1002/Cbic.200800051 |
0.742 |
|
| 2008 |
Young DD, Edwards WF, Lusic H, Lively MO, Deiters A. Light-triggered polymerase chain reaction. Chemical Communications (Cambridge, England). 462-4. PMID 18188468 DOI: 10.1039/B715152G |
0.719 |
|
| 2007 |
Senaiar RS, Teske JA, Young DD, Deiters A. Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization. The Journal of Organic Chemistry. 72: 7801-4. PMID 17824655 DOI: 10.1021/Jo7013565 |
0.719 |
|
| 2007 |
Young DD, Sripada L, Deiters A. Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry. Journal of Combinatorial Chemistry. 9: 735-8. PMID 17658900 DOI: 10.1021/Cc070068B |
0.728 |
|
| 2007 |
Young DD, Deiters A. A general approach to chemo- and regioselective cyclotrimerization reactions. Angewandte Chemie (International Ed. in English). 46: 5187-90. PMID 17526034 DOI: 10.1002/Anie.200700802 |
0.721 |
|
| 2007 |
Young DD, Deiters A. Photochemical activation of protein expression in bacterial cells. Angewandte Chemie (International Ed. in English). 46: 4290-2. PMID 17458846 DOI: 10.1002/Anie.200700057 |
0.739 |
|
| 2007 |
Lusic H, Young DD, Lively MO, Deiters A. Photochemical DNA activation. Organic Letters. 9: 1903-6. PMID 17447773 DOI: 10.1021/Ol070455U |
0.728 |
|
| 2007 |
Young DD, Deiters A. Photochemical control of biological processes. Organic & Biomolecular Chemistry. 5: 999-1005. PMID 17377650 DOI: 10.1039/B616410M |
0.72 |
|
| 2006 |
Young DD, Senaiar RS, Deiters A. Solid-supported [2+2+2] cyclotrimerizations. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 5563-8. PMID 16755631 DOI: 10.1002/Chem.200501360 |
0.741 |
|
| 2006 |
Senaiar RS, Young DD, Deiters A. Pyridines via solid-supported [2 + 2 + 2] cyclotrimerization. Chemical Communications (Cambridge, England). 1313-5. PMID 16538258 DOI: 10.1039/B515901F |
0.692 |
|
| 2006 |
Young DD, Deiters A. Photochemical hammerhead ribozyme activation. Bioorganic & Medicinal Chemistry Letters. 16: 2658-61. PMID 16513347 DOI: 10.1016/J.Bmcl.2006.02.034 |
0.719 |
|
| 2006 |
Deiters A, Young D, Senaiar R. Solid-Supported [2+2+2] Cyclotrimerizations Catalyzed by Rh and Ru Synfacts. 2006: 1079-1079. DOI: 10.1055/s-2006-949298 |
0.618 |
|
| 2006 |
Deiters A, Senaiar R, Young D. Polymer-Supported Synthesis of Pyridines via [2+2+2] Cycloaddition Synfacts. 2006: 0627-0627. DOI: 10.1055/s-2006-941797 |
0.605 |
|
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