Scott E. Schaus - Publications

Chemistry Boston University, Boston, MA, United States 
development of asymmetric catalytic reactions for synthesis, new methodologies for library synthesis, and drug target identification and validation

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Smith MJ, Reichl KD, Escobar RA, Heavey T, Coker DF, Schaus SE, Porco JA. Asymmetric Synthesis of Griffipavixanthone Employing a Chiral Phosphoric Acid-Catalyzed Cycloaddition. Journal of the American Chemical Society. PMID 30566336 DOI: 10.1021/jacs.8b12520  0.36
2018 Wong CR, Hummel G, Cai Y, Schaus SE, Panek JS. [4 + 2]-Cycloaddition and 1,4-Addition of ortho-Quinone Methides by a Chiral Crotyl Silane. Organic Letters. PMID 30557029 DOI: 10.1021/acs.orglett.8b03395  0.72
2018 Yang X, Jounaidi Y, Dai JB, Marte-Oquendo F, Halpin ES, Brown LE, Trilles R, Xu W, Daigle R, Yu B, Schaus SE, Porco JA, Forman SA. High-throughput Screening in Larval Zebrafish Identifies Novel Potent Sedative-hypnotics. Anesthesiology. PMID 29894316 DOI: 10.1097/ALN.0000000000002281  0.36
2017 Tardiff DF, Brown LE, Yan X, Trilles R, Jui NT, Barrasa MI, Caldwell KA, Caldwell GA, Schaus SE, Lindquist S. Dihydropyrimidine-thiones and clioquinol synergize to target β-amyloid cellular pathologies through a metal-dependent mechanism. Acs Chemical Neuroscience. PMID 28628299 DOI: 10.1021/acschemneuro.7b00187  0.36
2017 Allen EE, Zhu C, Panek JS, Schaus SE. Multicomponent Condensation Reactions via ortho-Quinone Methides. Organic Letters. PMID 28357870 DOI: 10.1021/acs.orglett.7b00647  0.72
2015 Barbato KS, Luan Y, Ramella D, Panek JS, Schaus SE. Enantioselective Multicomponent Condensation Reactions of Phenols, Aldehydes, and Boronates Catalyzed by Chiral Biphenols. Organic Letters. PMID 26576776 DOI: 10.1021/acs.orglett.5b02954  1
2015 Luan Y, Barbato KS, Moquist PN, Kodama T, Schaus SE. Enantioselective synthesis of 1,2-dihydronaphthalene-1-carbaldehydes by addition of boronates to isochromene acetals catalyzed by tartaric acid. Journal of the American Chemical Society. 137: 3233-6. PMID 25715172 DOI: 10.1021/jacs.5b00757  1
2015 Rajasekaran D, Siddiq A, Willoughby JLS, Biagi JM, Christadore LM, Yunes SA, Gredler R, Jariwala N, Robertson CL, Akiel MA, Shen XN, Subler MA, Windle JJ, Schaus SE, Fisher PB, et al. Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model Oncotarget. 6: 26266-26277. DOI: 10.18632/oncotarget.4656  1
2014 Luan Y, Qi Y, Yu J, Gao H, Schaus SE. The development of a novel HAuCl4@MOF catalyst and its catalytic application in the formation of dihydrochalcones. Rsc Advances. 4: 34199-34203. PMID 26989477 DOI: 10.1039/C4RA05256K  1
2014 Luan Y, Qi Y, Gao H, Ma Q, Schaus SE. Brønsted Acid/Lewis Acid Cooperatively Catalyzed Addition of Diazoester to 2H-chromene Acetals. European Journal of Organic Chemistry. 2014: 6868-6872. PMID 25411552 DOI: 10.1002/ejoc.201403043  1
2014 Luan Y, Yu J, Zhang X, Schaus SE, Wang G. Diastereoselective three-component synthesis of β-amino carbonyl compounds using diazo compounds, boranes, and acyl imines under catalyst-free conditions. The Journal of Organic Chemistry. 79: 4694-8. PMID 24787904 DOI: 10.1021/jo5003505  1
2014 Christadore LM, Pham L, Kolaczyk ED, Schaus SE. Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets. Bmc Systems Biology. 8: 7. PMID 24444313 DOI: 10.1186/1752-0509-8-7  1
2014 Zandparsa R, Talua NA, Finkelman MD, Schaus SE. An in vitro comparison of shear bond strength of zirconia to enamel using different surface treatments. Journal of Prosthodontics : Official Journal of the American College of Prosthodontists. 23: 117-23. PMID 23890275 DOI: 10.1111/jopr.12075  1
2014 Luan Y, Qi Y, Yu J, Gao H, Schaus SE. The development of a novel HAuCl4@MOF catalyst and its catalytic application in the formation of dihydrochalcones Rsc Advances. 4: 34199-34203. DOI: 10.1039/c4ra05256k  1
2013 Xiong Y, Schaus SE, Porco JA. Metal-catalyzed cascade rearrangements of 3-alkynyl flavone ethers. Organic Letters. 15: 1962-5. PMID 23574045 DOI: 10.1021/ol400631b  1
2013 Yang S, Pham L, Christadore LM, Schaus S, Kolaczyk ED. Multiscale gene sets from protein interaction networks 2013 Ieee Global Conference On Signal and Information Processing, Globalsip 2013 - Proceedings. 435-438. DOI: 10.1109/GlobalSIP.2013.6736908  1
2012 Luan Y, Schaus SE. Enantioselective addition of boronates to o-quinone methides catalyzed by chiral biphenols. Journal of the American Chemical Society. 134: 19965-8. PMID 23206197 DOI: 10.1021/ja309076g  1
2012 Peritore CS, Ho A, Yamamoto BK, Schaus SE. Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells. Neuroreport. 23: 989-94. PMID 23114623 DOI: 10.1097/WNR.0b013e32835a4ea4  1
2012 Ma Z, Ni F, Woo GH, Lo SM, Roveto PM, Schaus SE, Snyder JK. An intramolecular inverse electron demand Diels-Alder approach to annulated α-carbolines. Beilstein Journal of Organic Chemistry. 8: 829-40. PMID 23015831 DOI: 10.3762/bjoc.8.93  1
2012 Grant TJ, Bishop JA, Christadore LM, Barot G, Chin HG, Woodson S, Kavouris J, Siddiq A, Gredler R, Shen XN, Sherman J, Meehan T, Fitzgerald K, Pradhan S, Briggs LA, ... ... Schaus SE, et al. Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 109: 4503-8. PMID 22396589 DOI: 10.1073/pnas.1121601109  1
2012 Dower K, Filone CM, Hodges EN, Bjornson ZB, Rubins KH, Brown LE, Schaus S, Hensley LE, Connor JH. Identification of a pyridopyrimidinone inhibitor of orthopoxviruses from a diversity-oriented synthesis library. Journal of Virology. 86: 2632-40. PMID 22205744 DOI: 10.1128/JVI.05416-11  1
2011 Luan Y, Sun H, Schaus SE. Iron-catalyzed rearrangements and cycloaddition reactions of 2H-chromenes. Organic Letters. 13: 6480-3. PMID 22098535 DOI: 10.1021/ol202772k  1
2011 Kodama T, Moquist PN, Schaus SE. Enantioselective boronate additions to N-acyl quinoliniums catalyzed by tartaric acid. Organic Letters. 13: 6316-9. PMID 22067040 DOI: 10.1021/ol2028702  1
2011 Pham L, Christadore L, Schaus S, Kolaczyk ED. Network-based prediction for sources of transcriptional dysregulation using latent pathway identification analysis. Proceedings of the National Academy of Sciences of the United States of America. 108: 13347-52. PMID 21788508 DOI: 10.1073/pnas.1100891108  1
2011 Muncipinto G, Moquist PN, Schreiber SL, Schaus SE. Catalytic diastereoselective petasis reactions. Angewandte Chemie (International Ed. in English). 50: 8172-5. PMID 21751322 DOI: 10.1002/anie.201103271  1
2011 Brown LE, Dai P, Porco JA, Schaus SE. Gold catalyzed cyclization of alkyne-tethered dihydropyrimidones. Organic Letters. 13: 4228-31. PMID 21749159 DOI: 10.1021/ol2015658  1
2011 Medeiros MR, Schaus SE, Porco JA. A cycloisomerization/Friedel-Crafts alkylation strategy for the synthesis of pyrano[3,4-b]indoles. Organic Letters. 13: 4012-5. PMID 21740020 DOI: 10.1021/ol201532k  1
2011 Barnett DS, Schaus SE. Asymmetric propargylation of ketones using allenylboronates catalyzed by chiral biphenols. Organic Letters. 13: 4020-3. PMID 21732609 DOI: 10.1021/ol201535b  1
2011 Brown LE, Chih-Chien Cheng K, Wei WG, Yuan P, Dai P, Trilles R, Ni F, Yuan J, MacArthur R, Guha R, Johnson RL, Su XZ, Dominguez MM, Snyder JK, Beeler AB, ... Schaus SE, et al. Discovery of new antimalarial chemotypes through chemical methodology and library development. Proceedings of the National Academy of Sciences of the United States of America. 108: 6775-80. PMID 21498685 DOI: 10.1073/pnas.1017666108  1
2011 Luan Y, Schaus SE. Multicomponent Mannich reactions with boron enolates derived from diazo esters and 9-BBN. Organic Letters. 13: 2510-3. PMID 21473584 DOI: 10.1021/ol200766t  1
2010 Ting A, Goss JM, McDougal NT, Schaus SE. Brønsted base catalysts. Topics in Current Chemistry. 291: 145-200. PMID 21494951 DOI: 10.1007/978-3-642-02815-1_23  1
2010 Goldstein C, Schroeder JC, Fortin JP, Goss JM, Schaus SE, Beinborn M, Kopin AS. Two naturally occurring mutations in the type 1 melanin-concentrating hormone receptor abolish agonist-induced signaling. The Journal of Pharmacology and Experimental Therapeutics. 335: 799-806. PMID 20833795 DOI: 10.1124/jpet.110.174029  1
2010 Moquist PN, Kodama T, Schaus SE. Enantioselective addition of boronates to chromene acetals catalyzed by a chiral Brønsted acid/Lewis acid system. Angewandte Chemie (International Ed. in English). 49: 7096-100. PMID 20721997 DOI: 10.1002/anie.201003469  1
2010 Medeiros MR, Narayan RS, McDougal NT, Schaus SE, Porco JA. Skeletal diversity via cationic rearrangements of substituted dihydropyrans. Organic Letters. 12: 3222-5. PMID 20550144 DOI: 10.1021/ol101144k  1
2010 Marié JC, Xiong Y, Min GK, Yeager AR, Taniguchi T, Berova N, Schaus SE, Porco JA. Enantioselective synthesis of 3,4-chromanediones via asymmetric rearrangement of 3-allyloxyflavones. The Journal of Organic Chemistry. 75: 4584-90. PMID 20527786 DOI: 10.1021/jo100889c  1
2009 Barnett DS, Moquist PN, Schaus SE. The mechanism and an improved asymmetric allylboration of ketones catalyzed by chiral biphenols. Angewandte Chemie (International Ed. in English). 48: 8679-82. PMID 19816902 DOI: 10.1002/anie.200904715  1
2009 Bishop JA, Lou S, Schaus SE. Enantioselective addition of boronates to acyl imines catalyzed by chiral biphenols. Angewandte Chemie (International Ed. in English). 48: 4337-40. PMID 19431168 DOI: 10.1002/anie.200901023  1
2009 Goss JM, Dai P, Lou S, Schaus SE, Brkovic T, Hughes D. Enantioselective preparation of dihydropyrimidones [(5)-1-Benzyl-6-Methy1- 2-OXO-4-Phenyl-1, 2,3, 4-Tetrahydropyrimidine-5-Carboxylic methyl ester] Organic Syntheses. 86: 236-251.  1
2008 Goss JM, Schaus SE. Enantioselective synthesis of SNAP-7941: chiral dihydropyrimidone inhibitor of MCH1-R. The Journal of Organic Chemistry. 73: 7651-6. PMID 18767801 DOI: 10.1021/jo801463j  1
2008 Lou S, Schaus SE. Asymmetric petasis reactions catalyzed by chiral biphenols. Journal of the American Chemical Society. 130: 6922-3. PMID 18459782 DOI: 10.1021/ja8018934  1
2007 Lou S, Dai P, Schaus SE. Asymmetric Mannich reaction of dicarbonyl compounds with alpha-amido sulfones catalyzed by cinchona alkaloids and synthesis of chiral dihydropyrimidones. The Journal of Organic Chemistry. 72: 9998-10008. PMID 18047372 DOI: 10.1021/jo701777g  1
2007 Lou S, Moquist PN, Schaus SE. Asymmetric allylboration of acyl imines catalyzed by chiral diols. Journal of the American Chemical Society. 129: 15398-404. PMID 18020334 DOI: 10.1021/ja075204v  1
2007 Dominguez MM, Wathier M, Grinstaff MW, Schaus SE. Immobilized hydrogels for screening of molecular interactions. Analytical Chemistry. 79: 1064-6. PMID 17263336 DOI: 10.1021/ac061709c  1
2007 Ting A, Schaus SE. Organocatalytic asymmetric mannich reactions: New methodology, catalyst design, and synthetic applications European Journal of Organic Chemistry. 5797-5815. DOI: 10.1002/ejoc.200700409  1
2007 Ting A, Schaus SE. Organocatalysis and library development: Chiral heterocycles via the Cinchona alkaloid-catalyzed mannich reaction Chemtracts. 20: 169-180.  1
2006 Yeager AR, Min GK, Porco JA, Schaus SE. Exploring skeletal diversity via ring contraction of glycal-derived scaffolds. Organic Letters. 8: 5065-8. PMID 17048844 DOI: 10.1021/ol0618252  1
2006 Landon MR, Schaus SE. JEDA: Joint entropy diversity analysis. An information-theoretic method for choosing diverse and representative subsets from combinatorial libraries. Molecular Diversity. 10: 333-9. PMID 17031536 DOI: 10.1007/s11030-006-9042-4  1
2006 Lou S, Moquist PN, Schaus SE. Asymmetric allylboration of ketones catalyzed by chiral diols. Journal of the American Chemical Society. 128: 12660-1. PMID 17002355 DOI: 10.1021/ja0651308  1
2006 Rodgen SA, Schaus SE. Efficient construction of the clerodane decalin core by an asymmetric Morita-Baylis-Hillman reaction/Lewis acid promoted annulation strategy. Angewandte Chemie (International Ed. in English). 45: 4929-32. PMID 16802391 DOI: 10.1002/anie.200601076  1
2006 Ting A, Lou S, Schaus SE. Highly diastereoselective asymmetric Mannich reactions of 1,3-dicarbonyls with acyl imines. Organic Letters. 8: 2003-6. PMID 16671767 DOI: 10.1021/ol060304b  1
2006 McDougal NT, Schaus SE. Highly diastereoselective synthesis of bicyclo[3.2.1]octenones through phosphine-mediated condensations of 1,4-dien-3-ones. Angewandte Chemie (International Ed. in English). 45: 3117-9. PMID 16596692 DOI: 10.1002/anie.200600126  1
2006 Bode CM, Ting A, Schaus SE. A general organic catalyst for asymmetric addition of stabilized nucleophiles to acyl imines Tetrahedron. 62: 11499-11505. DOI: 10.1016/j.tet.2006.07.071  1
2005 Lou S, Taoka BM, Ting A, Schaus SE. Asymmetric Mannich reactions of beta-keto esters with acyl imines catalyzed by cinchona alkaloids. Journal of the American Chemical Society. 127: 11256-7. PMID 16089450 DOI: 10.1021/ja0537373  1
2005 Su S, Acquilano DE, Arumugasamy J, Beeler AB, Eastwood EL, Giguere JR, Lan P, Lei X, Min GK, Yeager AR, Zhou Y, Panek JS, Snyder JK, Schaus SE, Porco JA. Convergent synthesis of a complex oxime library using chemical domain shuffling. Organic Letters. 7: 2751-4. PMID 15957938 DOI: 10.1021/ol051023r  1
2005 Beeler AB, Schaus SE, Porco JA. Chemical library synthesis using convergent approaches. Current Opinion in Chemical Biology. 9: 277-84. PMID 15939329 DOI: 10.1016/j.cbpa.2005.04.005  1
2005 di Bernardo D, Thompson MJ, Gardner TS, Chobot SE, Eastwood EL, Wojtovich AP, Elliott SJ, Schaus SE, Collins JJ. Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks. Nature Biotechnology. 23: 377-83. PMID 15765094 DOI: 10.1038/nbt1075  1
2004 Lou S, Westbrook JA, Schaus SE. Decarboxylative aldol reactions of allyl beta-keto esters via heterobimetallic catalysis. Journal of the American Chemical Society. 126: 11440-1. PMID 15366881 DOI: 10.1021/ja045981k  1
2004 Su S, Giguere JR, Schaus SE, Porco JA. Synthesis of complex alkoxyamines using a polymer-supported N-hydroxyphthalimide Tetrahedron. 60: 8645-8657. DOI: 10.1016/j.tet.2004.05.109  1
2004 McDougal NT, Trevellini WL, Rodgen SA, Kliman LT, Schaus SE. The development of the asymmetric Morita-Baylis-Hillman reaction catalyzed by chiral Brønsted acids Advanced Synthesis and Catalysis. 346: 1231-1240. DOI: 10.1002/adsc.200404122  1
2003 McDougal NT, Schaus SE. Asymmetric Morita-Baylis-Hillman reactions catalyzed by chiral Brønsted acids. Journal of the American Chemical Society. 125: 12094-5. PMID 14518986 DOI: 10.1021/ja037705w  1
2003 Eastwood EL, Schaus SE. Borrelidin induces the transcription of amino acid biosynthetic enzymes via a GCN4-dependent pathway. Bioorganic & Medicinal Chemistry Letters. 13: 2235-7. PMID 12798341 DOI: 10.1016/S0960-894X(03)00406-2  1
2002 Plowright AT, Schaus SE, Myers AG. Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity. Chemistry & Biology. 9: 607-18. PMID 12031667 DOI: 10.1016/S1074-5521(02)00137-0  1
2002 Myers AG, Glatthar R, Hammond M, Harrington PM, Kuo EY, Liang J, Schaus SE, Wu Y, Xiang JN. Development of an enantioselective synthetic route to neocarzinostatin chromophore and its use for multiple radioisotopic incorporation. Journal of the American Chemical Society. 124: 5380-401. PMID 11996579 DOI: 10.1021/ja012487x  1
2002 Schaus SE, Brandes BD, Larrow JF, Tokunaga M, Hansen KB, Gould AE, Furrow ME, Jacobsen EN. Highly selective hydrolytic kinetic resolution of terminal epoxides catalyzed by chiral (salen)Co(III) complexes. Practical synthesis of enantioenriched terminal epoxides and 1,2-diols. Journal of the American Chemical Society. 124: 1307-15. PMID 11841300 DOI: 10.1021/ja016737l  1
2001 Schaus SE, Cavalieri D, Myers AG. Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein-chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure. Proceedings of the National Academy of Sciences of the United States of America. 98: 11075-80. PMID 11562456 DOI: 10.1073/pnas.191340698  1
2000 Schaus SE, Jacobsen EN. Asymmetric ring opening of meso epoxides with TMSCN catalyzed by (pybox)lanthanide complexes. Organic Letters. 2: 1001-4. PMID 10768207  1
1998 Furrow ME, Schaus SE, Jacobsen EN. Practical Access to Highly Enantioenriched C-3 Building Blocks via Hydrolytic Kinetic Resolution. The Journal of Organic Chemistry. 63: 6776-6777. PMID 11672291  1
1998 Schaus SE, Brånalt J, Jacobsen EN. Total synthesis of muconin by efficient assembly of chiral building blocks Journal of Organic Chemistry. 63: 4876-4877. DOI: 10.1021/jo9810765  1
1998 Dakin LA, Schaus SE, Jacobsen EN, Panek JS. Carbenoid insertions into the silicon-hydrogen bond catalyzed by chiral copper (I) Schiff base complexes Tetrahedron Letters. 39: 8947-8950.  1
1996 Larrow JF, Schaus SE, Jacobsen EN. Kinetic resolution of terminal epoxides via highly regioselective and enantioselective ring opening with TMSN3. An efficient, catalytic route to 1,2-amino alcohols Journal of the American Chemical Society. 118: 7420-7421. DOI: 10.1021/ja961708+  1
1996 Schaus SE, Jacobsen EN. Dynamic kinetic resolution of epichlorohydrin via enantioselective catalytic ring opening with TMSN3. Practical synthesis of aryl oxazolidinone antibacterial agents Tetrahedron Letters. 37: 7937-7940. DOI: 10.1016/0040-4039(96)01835-7  1
Show low-probability matches.