Scott E. Schaus - Publications

Affiliations: 
Chemistry Boston University, Boston, MA, United States 
Area:
development of asymmetric catalytic reactions for synthesis, new methodologies for library synthesis, and drug target identification and validation
Website:
http://www.bu.edu/chemistry/faculty/schaus/

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Rinaolo VJ, Robinson EE, Diagne AB, Schaus SE, Thomson RJ. Diene Synthesis by the Reductive Transposition of 1,2-Allenols Synlett. 30: 2073-2076. DOI: 10.1055/S-0039-1690692  0.386
2018 Smith MJ, Reichl KD, Escobar RA, Heavey T, Coker DF, Schaus SE, Porco JA. Asymmetric Synthesis of Griffipavixanthone Employing a Chiral Phosphoric Acid-Catalyzed Cycloaddition. Journal of the American Chemical Society. PMID 30566336 DOI: 10.1021/Jacs.8B12520  0.478
2018 Wong CR, Hummel G, Cai Y, Schaus SE, Panek JS. [4 + 2]-Cycloaddition and 1,4-Addition of ortho-Quinone Methides by a Chiral Crotyl Silane. Organic Letters. PMID 30557029 DOI: 10.1021/Acs.Orglett.8B03395  0.48
2018 Yang X, Jounaidi Y, Dai JB, Marte-Oquendo F, Halpin ES, Brown LE, Trilles R, Xu W, Daigle R, Yu B, Schaus SE, Porco JA, Forman SA. High-throughput Screening in Larval Zebrafish Identifies Novel Potent Sedative-hypnotics. Anesthesiology. PMID 29894316 DOI: 10.1097/Aln.0000000000002281  0.486
2017 Schaus SE, Jiang Y, Thomson RJ. Asymmetric Traceless Petasis Borono-Mannich Reactions of Enals: Reductive Transpositions of Allylic Diazenes. Angewandte Chemie (International Ed. in English). PMID 29110383 DOI: 10.1002/Anie.201708784  0.531
2017 Tardiff DF, Brown LE, Yan X, Trilles R, Jui NT, Barrasa MI, Caldwell KA, Caldwell GA, Schaus SE, Lindquist S. Dihydropyrimidine-thiones and clioquinol synergize to target β-amyloid cellular pathologies through a metal-dependent mechanism. Acs Chemical Neuroscience. PMID 28628299 DOI: 10.1021/Acschemneuro.7B00187  0.48
2017 Allen EE, Zhu C, Panek JS, Schaus SE. Multicomponent Condensation Reactions via ortho-Quinone Methides. Organic Letters. PMID 28357870 DOI: 10.1021/Acs.Orglett.7B00647  0.49
2017 Jiang Y, Diagne AB, Thomson RJ, Schaus SE. Enantioselective Synthesis of Allenes by Catalytic Traceless Petasis Reactions. Journal of the American Chemical Society. PMID 28121128 DOI: 10.1021/Jacs.6B11937  0.545
2017 Jiang Y, Schaus SE. Asymmetric Petasis Borono-Mannich Allylation Reactions Catalyzed by Chiral Biphenols. Angewandte Chemie (International Ed. in English). PMID 28052567 DOI: 10.1002/Anie.201611332  0.548
2015 Barbato KS, Luan Y, Ramella D, Panek JS, Schaus SE. Enantioselective Multicomponent Condensation Reactions of Phenols, Aldehydes, and Boronates Catalyzed by Chiral Biphenols. Organic Letters. PMID 26576776 DOI: 10.1021/Acs.Orglett.5B02954  0.83
2015 Luan Y, Barbato KS, Moquist PN, Kodama T, Schaus SE. Enantioselective synthesis of 1,2-dihydronaphthalene-1-carbaldehydes by addition of boronates to isochromene acetals catalyzed by tartaric acid. Journal of the American Chemical Society. 137: 3233-6. PMID 25715172 DOI: 10.1021/Jacs.5B00757  0.83
2014 Luan Y, Qi Y, Yu J, Gao H, Schaus SE. The development of a novel HAuCl4@MOF catalyst and its catalytic application in the formation of dihydrochalcones. Rsc Advances. 4: 34199-34203. PMID 26989477 DOI: 10.1039/C4Ra05256K  0.624
2014 Luan Y, Qi Y, Gao H, Ma Q, Schaus SE. Brønsted Acid/Lewis Acid Cooperatively Catalyzed Addition of Diazoester to 2H-chromene Acetals. European Journal of Organic Chemistry. 2014: 6868-6872. PMID 25411552 DOI: 10.1002/Ejoc.201403043  0.627
2014 Luan Y, Yu J, Zhang X, Schaus SE, Wang G. Diastereoselective three-component synthesis of β-amino carbonyl compounds using diazo compounds, boranes, and acyl imines under catalyst-free conditions. The Journal of Organic Chemistry. 79: 4694-8. PMID 24787904 DOI: 10.1021/Jo5003505  0.623
2014 Luan Y, Qi Y, Yu J, Gao H, Schaus SE. The development of a novel HAuCl4@MOF catalyst and its catalytic application in the formation of dihydrochalcones Rsc Advances. 4: 34199-34203. DOI: 10.1039/c4ra05256k  0.524
2013 Xiong Y, Schaus SE, Porco JA. Metal-catalyzed cascade rearrangements of 3-alkynyl flavone ethers. Organic Letters. 15: 1962-5. PMID 23574045 DOI: 10.1021/Ol400631B  0.34
2012 Luan Y, Schaus SE. Enantioselective addition of boronates to o-quinone methides catalyzed by chiral biphenols. Journal of the American Chemical Society. 134: 19965-8. PMID 23206197 DOI: 10.1021/Ja309076G  0.626
2012 Peritore CS, Ho A, Yamamoto BK, Schaus SE. Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells. Neuroreport. 23: 989-94. PMID 23114623 DOI: 10.1097/Wnr.0B013E32835A4Ea4  0.742
2012 Ma Z, Ni F, Woo GH, Lo SM, Roveto PM, Schaus SE, Snyder JK. An intramolecular inverse electron demand Diels-Alder approach to annulated α-carbolines. Beilstein Journal of Organic Chemistry. 8: 829-40. PMID 23015831 DOI: 10.3762/Bjoc.8.93  0.347
2012 Grant TJ, Bishop JA, Christadore LM, Barot G, Chin HG, Woodson S, Kavouris J, Siddiq A, Gredler R, Shen XN, Sherman J, Meehan T, Fitzgerald K, Pradhan S, Briggs LA, ... ... Schaus SE, et al. Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 109: 4503-8. PMID 22396589 DOI: 10.1073/Pnas.1121601109  0.541
2012 Dower K, Filone CM, Hodges EN, Bjornson ZB, Rubins KH, Brown LE, Schaus S, Hensley LE, Connor JH. Identification of a pyridopyrimidinone inhibitor of orthopoxviruses from a diversity-oriented synthesis library. Journal of Virology. 86: 2632-40. PMID 22205744 DOI: 10.1128/Jvi.05416-11  0.506
2011 Luan Y, Sun H, Schaus SE. Iron-catalyzed rearrangements and cycloaddition reactions of 2H-chromenes. Organic Letters. 13: 6480-3. PMID 22098535 DOI: 10.1021/Ol202772K  0.601
2011 Kodama T, Moquist PN, Schaus SE. Enantioselective boronate additions to N-acyl quinoliniums catalyzed by tartaric acid. Organic Letters. 13: 6316-9. PMID 22067040 DOI: 10.1021/Ol2028702  0.808
2011 Muncipinto G, Moquist PN, Schreiber SL, Schaus SE. Catalytic diastereoselective petasis reactions. Angewandte Chemie (International Ed. in English). 50: 8172-5. PMID 21751322 DOI: 10.1002/Anie.201103271  0.832
2011 Brown LE, Dai P, Porco JA, Schaus SE. Gold catalyzed cyclization of alkyne-tethered dihydropyrimidones. Organic Letters. 13: 4228-31. PMID 21749159 DOI: 10.1021/Ol2015658  0.637
2011 Medeiros MR, Schaus SE, Porco JA. A cycloisomerization/Friedel-Crafts alkylation strategy for the synthesis of pyrano[3,4-b]indoles. Organic Letters. 13: 4012-5. PMID 21740020 DOI: 10.1021/Ol201532K  0.474
2011 Barnett DS, Schaus SE. Asymmetric propargylation of ketones using allenylboronates catalyzed by chiral biphenols. Organic Letters. 13: 4020-3. PMID 21732609 DOI: 10.1021/Ol201535B  0.532
2011 Brown LE, Chih-Chien Cheng K, Wei WG, Yuan P, Dai P, Trilles R, Ni F, Yuan J, MacArthur R, Guha R, Johnson RL, Su XZ, Dominguez MM, Snyder JK, Beeler AB, ... Schaus SE, et al. Discovery of new antimalarial chemotypes through chemical methodology and library development. Proceedings of the National Academy of Sciences of the United States of America. 108: 6775-80. PMID 21498685 DOI: 10.1073/Pnas.1017666108  0.52
2011 Luan Y, Schaus SE. Multicomponent Mannich reactions with boron enolates derived from diazo esters and 9-BBN. Organic Letters. 13: 2510-3. PMID 21473584 DOI: 10.1021/Ol200766T  0.664
2011 Ting A, Goss JM, McDougal NT, Schaus SE. ChemInform Abstract: Bronsted Base Catalysts Cheminform. 42: no-no. DOI: 10.1002/chin.201123230  0.78
2010 Ting A, Goss JM, McDougal NT, Schaus SE. Brønsted base catalysts. Topics in Current Chemistry. 291: 145-200. PMID 21494951 DOI: 10.1007/978-3-642-02815-1_23  0.807
2010 Moquist PN, Kodama T, Schaus SE. Enantioselective addition of boronates to chromene acetals catalyzed by a chiral Brønsted acid/Lewis acid system. Angewandte Chemie (International Ed. in English). 49: 7096-100. PMID 20721997 DOI: 10.1002/Anie.201003469  0.824
2010 Medeiros MR, Narayan RS, McDougal NT, Schaus SE, Porco JA. Skeletal diversity via cationic rearrangements of substituted dihydropyrans. Organic Letters. 12: 3222-5. PMID 20550144 DOI: 10.1021/Ol101144K  0.81
2010 Marié JC, Xiong Y, Min GK, Yeager AR, Taniguchi T, Berova N, Schaus SE, Porco JA. Enantioselective synthesis of 3,4-chromanediones via asymmetric rearrangement of 3-allyloxyflavones. The Journal of Organic Chemistry. 75: 4584-90. PMID 20527786 DOI: 10.1021/Jo100889C  0.434
2010 Schaus S, Moquist P, Kodama T. Combined Acid System for Asymmetric Addition of Boronates to Chromene Acetals Synfacts. 2010: 1397-1397. DOI: 10.1055/S-0030-1258896  0.79
2010 Schaus S, Porco Jr. J, Marié J, Xiong Y, Min G, Yeager A, Taniguchi T, Berova N. Lewis Acid Catalyzed Asymmetric Rearrangement of 3-Allyloxyflavones Synfacts. 2010: 1169-1169. DOI: 10.1055/S-0030-1258683  0.447
2010 Barnett DS, Moquist PN, Schaus SE. Mechanistic Insight in an Improved Allylboration of Ketones Synfacts. 2010: 111-111. DOI: 10.1055/S-0029-1218487  0.773
2010 Myers AG, Glatthar R, Hammond M, Harrington PM, Kuo EY, Liang J, Schaus SE, Wu Y, Xiang J. ChemInform Abstract: Development of an Enantioselective Synthetic Route to Neocarzinostatin Chromophore and Its Use for Multiple Radioisotopic Incorporation. Cheminform. 33: no-no. DOI: 10.1002/chin.200236229  0.515
2010 SCHAUS SE, BRAANALT J, JACOBSEN EN. ChemInform Abstract: Asymmetric Hetero-Diels-Alder Reactions Catalyzed by Chiral (Salen)Chromium(III) Complexes. Cheminform. 29: no-no. DOI: 10.1002/chin.199825159  0.598
2009 Barnett DS, Moquist PN, Schaus SE. The mechanism and an improved asymmetric allylboration of ketones catalyzed by chiral biphenols. Angewandte Chemie (International Ed. in English). 48: 8679-82. PMID 19816902 DOI: 10.1002/Anie.200904715  0.828
2009 Bishop JA, Lou S, Schaus SE. Enantioselective addition of boronates to acyl imines catalyzed by chiral biphenols. Angewandte Chemie (International Ed. in English). 48: 4337-40. PMID 19431168 DOI: 10.1002/Anie.200901023  0.764
2009 Goss JM, Dai P, Lou S, Schaus SE. Enantioselective Preparation of Dihydropyrimidones Organic Syntheses. 236-251. DOI: 10.1002/0471264229.Os086.23  0.591
2009 Goss JM, Dai P, Lou S, Schaus SE, Brkovic T, Hughes D. Enantioselective preparation of dihydropyrimidones [(5)-1-Benzyl-6-Methy1- 2-OXO-4-Phenyl-1, 2,3, 4-Tetrahydropyrimidine-5-Carboxylic methyl ester] Organic Syntheses. 86: 236-251.  0.524
2008 Goss JM, Schaus SE. Enantioselective synthesis of SNAP-7941: chiral dihydropyrimidone inhibitor of MCH1-R. The Journal of Organic Chemistry. 73: 7651-6. PMID 18767801 DOI: 10.1021/Jo801463J  0.511
2008 Lou S, Schaus SE. Asymmetric petasis reactions catalyzed by chiral biphenols. Journal of the American Chemical Society. 130: 6922-3. PMID 18459782 DOI: 10.1021/Ja8018934  0.706
2007 Lou S, Dai P, Schaus SE. Asymmetric Mannich reaction of dicarbonyl compounds with alpha-amido sulfones catalyzed by cinchona alkaloids and synthesis of chiral dihydropyrimidones. The Journal of Organic Chemistry. 72: 9998-10008. PMID 18047372 DOI: 10.1021/Jo701777G  0.703
2007 Lou S, Moquist PN, Schaus SE. Asymmetric allylboration of acyl imines catalyzed by chiral diols. Journal of the American Chemical Society. 129: 15398-404. PMID 18020334 DOI: 10.1021/Ja075204V  0.838
2007 Ting A, Schaus SE. Organocatalytic asymmetric mannich reactions: New methodology, catalyst design, and synthetic applications European Journal of Organic Chemistry. 5797-5815. DOI: 10.1002/Ejoc.200700409  0.712
2007 Ting A, Schaus SE. Organocatalysis and library development: Chiral heterocycles via the Cinchona alkaloid-catalyzed mannich reaction Chemtracts. 20: 169-180.  0.671
2006 Yeager AR, Min GK, Porco JA, Schaus SE. Exploring skeletal diversity via ring contraction of glycal-derived scaffolds. Organic Letters. 8: 5065-8. PMID 17048844 DOI: 10.1021/Ol0618252  0.35
2006 Lou S, Moquist PN, Schaus SE. Asymmetric allylboration of ketones catalyzed by chiral diols. Journal of the American Chemical Society. 128: 12660-1. PMID 17002355 DOI: 10.1055/S-2006-955612  0.843
2006 Rodgen SA, Schaus SE. Efficient construction of the clerodane decalin core by an asymmetric Morita-Baylis-Hillman reaction/Lewis acid promoted annulation strategy. Angewandte Chemie (International Ed. in English). 45: 4929-32. PMID 16802391 DOI: 10.1002/Anie.200601076  0.808
2006 Ting A, Lou S, Schaus SE. Highly diastereoselective asymmetric Mannich reactions of 1,3-dicarbonyls with acyl imines. Organic Letters. 8: 2003-6. PMID 16671767 DOI: 10.1021/Ol060304B  0.762
2006 McDougal NT, Schaus SE. Highly diastereoselective synthesis of bicyclo[3.2.1]octenones through phosphine-mediated condensations of 1,4-dien-3-ones. Angewandte Chemie (International Ed. in English). 45: 3117-9. PMID 16596692 DOI: 10.1002/Anie.200600126  0.815
2006 Schaus S, Rodgen S. Clerodane-Derivatives by Catalytic Morita-Baylis-Hillman Reaction Synfacts. 2006: 0954-0954. DOI: 10.1055/s-2006-949229  0.811
2006 Bode CM, Ting A, Schaus SE. A general organic catalyst for asymmetric addition of stabilized nucleophiles to acyl imines Tetrahedron. 62: 11499-11505. DOI: 10.1016/J.Tet.2006.07.071  0.692
2005 Lou S, Taoka BM, Ting A, Schaus SE. Asymmetric Mannich reactions of beta-keto esters with acyl imines catalyzed by cinchona alkaloids. Journal of the American Chemical Society. 127: 11256-7. PMID 16089450 DOI: 10.1021/Ja0537373  0.757
2005 Su S, Acquilano DE, Arumugasamy J, Beeler AB, Eastwood EL, Giguere JR, Lan P, Lei X, Min GK, Yeager AR, Zhou Y, Panek JS, Snyder JK, Schaus SE, Porco JA. Convergent synthesis of a complex oxime library using chemical domain shuffling. Organic Letters. 7: 2751-4. PMID 15957938 DOI: 10.1021/Ol051023R  0.745
2005 Beeler AB, Schaus SE, Porco JA. Chemical library synthesis using convergent approaches. Current Opinion in Chemical Biology. 9: 277-84. PMID 15939329 DOI: 10.1016/J.Cbpa.2005.04.005  0.347
2005 di Bernardo D, Thompson MJ, Gardner TS, Chobot SE, Eastwood EL, Wojtovich AP, Elliott SJ, Schaus SE, Collins JJ. Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks. Nature Biotechnology. 23: 377-83. PMID 15765094 DOI: 10.1038/Nbt1075  0.738
2004 Lou S, Westbrook JA, Schaus SE. Decarboxylative aldol reactions of allyl beta-keto esters via heterobimetallic catalysis. Journal of the American Chemical Society. 126: 11440-1. PMID 15366881 DOI: 10.1021/Ja045981K  0.64
2004 Su S, Giguere JR, Schaus SE, Porco JA. Synthesis of complex alkoxyamines using a polymer-supported N-hydroxyphthalimide Tetrahedron. 60: 8645-8657. DOI: 10.1016/J.Tet.2004.05.109  0.764
2004 McDougal NT, Trevellini WL, Rodgen SA, Kliman LT, Schaus SE. The development of the asymmetric Morita-Baylis-Hillman reaction catalyzed by chiral Brønsted acids Advanced Synthesis and Catalysis. 346: 1231-1240. DOI: 10.1002/Adsc.200404122  0.808
2003 McDougal NT, Schaus SE. Asymmetric Morita-Baylis-Hillman reactions catalyzed by chiral Brønsted acids. Journal of the American Chemical Society. 125: 12094-5. PMID 14518986 DOI: 10.1021/Ja037705W  0.849
2003 Eastwood EL, Schaus SE. Borrelidin induces the transcription of amino acid biosynthetic enzymes via a GCN4-dependent pathway. Bioorganic & Medicinal Chemistry Letters. 13: 2235-7. PMID 12798341 DOI: 10.1016/S0960-894X(03)00406-2  0.749
2002 Plowright AT, Schaus SE, Myers AG. Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity. Chemistry & Biology. 9: 607-18. PMID 12031667 DOI: 10.1016/S1074-5521(02)00137-0  0.491
2002 Myers AG, Glatthar R, Hammond M, Harrington PM, Kuo EY, Liang J, Schaus SE, Wu Y, Xiang JN. Development of an enantioselective synthetic route to neocarzinostatin chromophore and its use for multiple radioisotopic incorporation. Journal of the American Chemical Society. 124: 5380-401. PMID 11996579 DOI: 10.1021/Ja012487X  0.683
2002 Schaus SE, Brandes BD, Larrow JF, Tokunaga M, Hansen KB, Gould AE, Furrow ME, Jacobsen EN. Highly selective hydrolytic kinetic resolution of terminal epoxides catalyzed by chiral (salen)Co(III) complexes. Practical synthesis of enantioenriched terminal epoxides and 1,2-diols. Journal of the American Chemical Society. 124: 1307-15. PMID 11841300 DOI: 10.1021/Ja016737L  0.81
2001 Schaus SE, Cavalieri D, Myers AG. Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein-chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure. Proceedings of the National Academy of Sciences of the United States of America. 98: 11075-80. PMID 11562456 DOI: 10.1073/Pnas.191340698  0.486
2000 Schaus SE, Jacobsen EN. Asymmetric ring opening of meso epoxides with TMSCN catalyzed by (pybox)lanthanide complexes. Organic Letters. 2: 1001-4. PMID 10768207 DOI: 10.1021/Ol005721H  0.618
1998 Furrow ME, Schaus SE, Jacobsen EN. Practical Access to Highly Enantioenriched C-3 Building Blocks via Hydrolytic Kinetic Resolution. The Journal of Organic Chemistry. 63: 6776-6777. PMID 11672291 DOI: 10.1021/Jo981332D  0.754
1998 Schaus SE, Brånalt J, Jacobsen EN. Total synthesis of muconin by efficient assembly of chiral building blocks Journal of Organic Chemistry. 63: 4876-4877. DOI: 10.1021/Jo9810765  0.495
1998 Schaus SE, Brånalt J, Jacobsen EN. Asymmetric Hetero-Diels−Alder Reactions Catalyzed by Chiral (Salen)Chromium(III) Complexes The Journal of Organic Chemistry. 63: 403-405. DOI: 10.1021/Jo971758C  0.638
1998 Dakin LA, Schaus SE, Jacobsen EN, Panek JS. Carbenoid insertions into the silicon-hydrogen bond catalyzed by chiral copper (I) Schiff base complexes Tetrahedron Letters. 39: 8947-8950. DOI: 10.1016/S0040-4039(98)02013-9  0.588
1997 Schaus SE, Larrow JF, Jacobsen EN. Practical Synthesis of Enantiopure Cyclic 1,2-Amino Alcohols via Catalytic Asymmetric Ring Opening of Meso Epoxides The Journal of Organic Chemistry. 62: 4197-4199. DOI: 10.1021/Jo970146P  0.564
1996 Larrow JF, Schaus SE, Jacobsen EN. Kinetic resolution of terminal epoxides via highly regioselective and enantioselective ring opening with TMSN3. An efficient, catalytic route to 1,2-amino alcohols Journal of the American Chemical Society. 118: 7420-7421. DOI: 10.1021/Ja961708+  0.576
1996 Schaus SE, Jacobsen EN. Dynamic kinetic resolution of epichlorohydrin via enantioselective catalytic ring opening with TMSN3. Practical synthesis of aryl oxazolidinone antibacterial agents Tetrahedron Letters. 37: 7937-7940. DOI: 10.1016/0040-4039(96)01835-7  0.6
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