Kalyan Pasunooti - Publications

Affiliations: 
Nanyang Technological University, Singapore, Singapore 

9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Voggu R, Karmakar A, Puli VS, Damerla VSB, Mogili P, Amaladass P, Chidara S, Pasunooti KK, Gupta S. Design, Synthesis, Molecular Docking Study and Biological Evaluation of Novel γ-Carboline Derivatives of Latrepirdine (Dimebon) as Potent Anticancer Agents. Molecules (Basel, Switzerland). 28. PMID 37446626 DOI: 10.3390/molecules28134965  0.361
2020 Li Y, Pasunooti KK, Peng H, Li RJ, Shi WQ, Liu W, Cheng Z, Head SA, Liu JO. Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors. Acs Medicinal Chemistry Letters. 11: 1111-1117. PMID 32550989 DOI: 10.1021/Acsmedchemlett.9B00438  0.671
2019 Zhong W, Pasunooti K, Balamkundu S, Wong YH, Nah Q, Gadi V, Gnanakalai S, Chionh YH, McBee ME, Gopal P, Lim SH, Olivier N, Buurman E, Dick T, Liu CF, et al. Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism. Journal of Medicinal Chemistry. PMID 31442049 DOI: 10.1021/acs.jmedchem.9b00582  0.381
2018 Li Y, Pasunooti KK, Li RJ, Liu W, Head SA, Shi WQ, Liu JO. Novel Tetrazole-containing Analogs of Itraconazole as Potent Anti-angiogenic Agents with Reduced CYP3A4 Inhibition. Journal of Medicinal Chemistry. PMID 30481027 DOI: 10.1021/Acs.Jmedchem.8B01252  0.725
2018 Bauer L, Ferla S, Head SA, Bhat S, Pasunooti KK, Shi WQ, Albulescu L, Liu JO, Brancale A, van Kuppeveld FJM, Strating JRPM. Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP). Antiviral Research. PMID 29807040 DOI: 10.1016/J.Antiviral.2018.05.010  0.79
2017 Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis. Acs Chemical Biology. 12: 174-182. PMID 28103683 DOI: 10.1021/Acschembio.6B00849  0.647
2015 Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26655341 DOI: 10.1073/Pnas.1512867112  0.756
2013 Harikishore A, Leow ML, Niang M, Rajan S, Pasunooti KK, Preiser PR, Liu X, Yoon HS. Adamantyl derivative as a potent inhibitor of Plasmodium FK506 binding protein 35. Acs Medicinal Chemistry Letters. 4: 1097-101. PMID 24900611 DOI: 10.1021/Ml400306R  0.458
2013 Leow ML, Chin HL, Yu PS, Pasunooti KK, Tay RX, Zhang D, Yoon HS, Liu XW. Benzofuran-based estrogen receptor α modulators as anti-cancer therapeutics: in silico and experimental studies. Current Medicinal Chemistry. 20: 2820-37. PMID 23531218 DOI: 10.2174/0929867311320220007  0.321
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