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Roy Kishony - Publications

Affiliations: 
Systems Biology Harvard Medical School, Boston, MA, United States 
Area:
system-level architecture of genetic networks
Website:
http://www.fas.harvard.edu/~biophys/Roy_Kishony.htm

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gross R, Yelin I, Lázár V, Datta MS, Kishony R. Beta-lactamase dependent and independent evolutionary paths to high-level ampicillin resistance. Nature Communications. 15: 5383. PMID 38918379 DOI: 10.1038/s41467-024-49621-2  0.386
2022 Shaer Tamar E, Kishony R. Multistep diversification in spatiotemporal bacterial-phage coevolution. Nature Communications. 13: 7971. PMID 36577749 DOI: 10.1038/s41467-022-35351-w  0.374
2022 Lázár V, Snitser O, Barkan D, Kishony R. Antibiotic combinations reduce Staphylococcus aureus clearance. Nature. PMID 36198788 DOI: 10.1038/s41586-022-05260-5  0.333
2022 Chung H, Merakou C, Schaefers MM, Flett KB, Martini S, Lu R, Blumenthal JA, Webster SS, Cross AR, Al Ahmar R, Halpin E, Anderson M, Moore NS, Snesrud EC, Yu HD, ... ... Kishony R, et al. Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections. Nature Communications. 13: 1231. PMID 35264582 DOI: 10.1038/s41467-022-28188-w  0.363
2022 Stracy M, Snitser O, Yelin I, Amer Y, Parizade M, Katz R, Rimler G, Wolf T, Herzel E, Koren G, Kuint J, Foxman B, Chodick G, Shalev V, Kishony R. Minimizing treatment-induced emergence of antibiotic resistance in bacterial infections. Science (New York, N.Y.). 375: 889-894. PMID 35201862 DOI: 10.1126/science.abg9868  0.308
2020 Russ D, Glaser F, Shaer Tamar E, Yelin I, Baym M, Kelsic ED, Zampaloni C, Haldimann A, Kishony R. Escape mutations circumvent a tradeoff between resistance to a beta-lactam and resistance to a beta-lactamase inhibitor. Nature Communications. 11: 2029. PMID 32332717 DOI: 10.1038/S41467-020-15666-2  0.673
2020 Andersson DI, Balaban NQ, Baquero F, Courvalin P, Glaser P, Gophna U, Kishony R, Molin S, Tønjum T. Antibiotic resistance: turning evolutionary principles into clinical reality. Fems Microbiology Reviews. PMID 31981358 DOI: 10.1093/Femsre/Fuaa001  0.438
2019 Yelin I, Flett KB, Merakou C, Mehrotra P, Stam J, Snesrud E, Hinkle M, Lesho E, McGann P, McAdam AJ, Sandora TJ, Kishony R, Priebe GP. Genomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients. Nature Medicine. PMID 31700189 DOI: 10.1038/S41591-019-0626-9  0.329
2019 Lázár V, Kishony R. Transient antibiotic resistance calls for attention. Nature Microbiology. 4: 1606-1607. PMID 31541208 DOI: 10.1038/S41564-019-0571-X  0.41
2019 Yelin I, Snitser O, Novich G, Katz R, Tal O, Parizade M, Chodick G, Koren G, Shalev V, Kishony R. Personal clinical history predicts antibiotic resistance of urinary tract infections. Nature Medicine. PMID 31273328 DOI: 10.1038/S41591-019-0503-6  0.411
2019 Kaminski Strauss S, Schirman D, Jona G, Brooks AN, Kunjapur AM, Nguyen Ba AN, Flint A, Solt A, Mershin A, Dixit A, Yona AH, Csörgő B, Busby BP, Hennig BP, Pál C, ... ... Kishony R, et al. Evolthon: A community endeavor to evolve lab evolution. Plos Biology. 17: e3000182. PMID 30925180 DOI: 10.1371/Journal.Pbio.3000182  0.336
2018 Datta MS, Kishony R. A spotlight on bacterial mutations for 75 years. Nature. 563: 633-644. PMID 30478371 DOI: 10.1038/D41586-018-07521-8  0.341
2018 Russ D, Kishony R. Additivity of inhibitory effects in multidrug combinations. Nature Microbiology. PMID 30323252 DOI: 10.1038/S41564-018-0252-1  0.335
2018 Palmer AC, Chait R, Kishony R. Non-optimal gene expression creates latent potential for antibiotic resistance. Molecular Biology and Evolution. PMID 30169679 DOI: 10.1093/Molbev/Msy163  0.421
2018 Wehrens M, Ershov D, Rozendaal R, Walker N, Schultz D, Kishony R, Levin PA, Tans SJ. Size Laws and Division Ring Dynamics in Filamentous Escherichia coli cells. Current Biology : Cb. PMID 29502951 DOI: 10.1016/J.Cub.2018.02.006  0.307
2018 Yelin I, Kishony R. Antibiotic Resistance. Cell. 172: 1136-1136.e1. PMID 29474914 DOI: 10.1016/j.cell.2018.02.018  0.354
2017 Schultz D, Palmer AC, Kishony R. Regulatory Dynamics Determine Cell Fate following Abrupt Antibiotic Exposure. Cell Systems. PMID 29102611 DOI: 10.1016/J.Cels.2017.10.002  0.392
2017 Chung H, Lieberman TD, Vargas SO, Flett KB, McAdam AJ, Priebe GP, Kishony R. Global and local selection acting on the pathogen Stenotrophomonas maltophilia in the human lung. Nature Communications. 8: 14078. PMID 28102223 DOI: 10.1038/Ncomms14078  0.375
2016 Gerardin Y, Springer M, Kishony R. A competitive trade-off limits the selective advantage of increased antibiotic production. Nature Microbiology. 1: 16175. PMID 27668360 DOI: 10.1038/Nmicrobiol.2016.175  0.424
2016 Stone LK, Baym M, Lieberman TD, Chait R, Clardy J, Kishony R. Compounds that select against the tetracycline-resistance efflux pump. Nature Chemical Biology. PMID 27642863 DOI: 10.1038/Nchembio.2176  0.696
2016 Baym M, Lieberman TD, Kelsic ED, Chait R, Gross R, Yelin I, Kishony R. Spatiotemporal microbial evolution on antibiotic landscapes. Science (New York, N.Y.). 353: 1147-51. PMID 27609891 DOI: 10.1126/Science.Aag0822  0.716
2016 Chait R, Palmer AC, Yelin I, Kishony R. Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments. Nature Communications. 7: 10333. PMID 26787239 DOI: 10.1038/Ncomms10333  0.451
2016 Baym M, Stone LK, Kishony R. Multidrug evolutionary strategies to reverse antibiotic resistance. Science (New York, N.Y.). 351: aad3292. PMID 26722002 DOI: 10.1126/Science.Aad3292  0.735
2015 Wang KK, Stone LK, Lieberman TD, Shavit M, Baasov T, Kishony R. A hybrid drug limits resistance by evading the action of the multiple antibiotic resistance pathway. Molecular Biology and Evolution. PMID 26538141 DOI: 10.1093/Molbev/Msv243  0.48
2015 Palmer AC, Toprak E, Baym M, Kim S, Veres A, Bershtein S, Kishony R. Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes. Nature Communications. 6: 7385. PMID 26060115 DOI: 10.1038/Ncomms8385  0.718
2015 Baym M, Kryazhimskiy S, Lieberman TD, Chung H, Desai MM, Kishony R. Inexpensive multiplexed library preparation for megabase-sized genomes. Plos One. 10: e0128036. PMID 26000737 DOI: 10.1371/Journal.Pone.0128036  0.639
2015 Kelsic ED, Zhao J, Vetsigian K, Kishony R. Counteraction of antibiotic production and degradation stabilizes microbial communities. Nature. 521: 516-9. PMID 25992546 DOI: 10.1038/Nature14485  0.337
2015 Selmecki AM, Maruvka YE, Richmond PA, Guillet M, Shoresh N, Sorenson AL, De S, Kishony R, Michor F, Dowell R, Pellman D. Polyploidy can drive rapid adaptation in yeast. Nature. 519: 349-52. PMID 25731168 DOI: 10.1038/Nature14187  0.379
2015 Baym M, Kryazhimskiy S, Lieberman TD, Chung H, Desai MM, Kishony R. Correction: Inexpensive multiplexed library preparation for megabase-sized genomes Plos One. 10. DOI: 10.1371/journal.pone.0131262  0.614
2014 Kishony R, Collins JJ. Editorial overview: Antimicrobials: grappling with the complexities of antibiotics and resistance. Current Opinion in Microbiology. 21: v-vi. PMID 25444122 DOI: 10.1016/J.Mib.2014.10.004  0.427
2014 Kim S, Lieberman TD, Kishony R. Alternating antibiotic treatments constrain evolutionary paths to multidrug resistance. Proceedings of the National Academy of Sciences of the United States of America. 111: 14494-9. PMID 25246554 DOI: 10.1073/Pnas.1409800111  0.48
2014 Palmer AC, Kishony R. Opposing effects of target overexpression reveal drug mechanisms. Nature Communications. 5: 4296. PMID 24980690 DOI: 10.1038/Ncomms5296  0.382
2014 Lieberman TD, Flett KB, Yelin I, Martin TR, McAdam AJ, Priebe GP, Kishony R. Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures. Nature Genetics. 46: 82-7. PMID 24316980 DOI: 10.1038/Ng.2848  0.402
2013 Toprak E, Veres A, Yildiz S, Pedraza JM, Chait R, Paulsson J, Kishony R. Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition. Nature Protocols. 8: 555-67. PMID 23429717 DOI: 10.1038/Nprot.Nprot.2013.021  0.615
2013 Palmer AC, Kishony R. Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance. Nature Reviews. Genetics. 14: 243-8. PMID 23419278 DOI: 10.1038/Nrg3351  0.485
2013 Toprak E, Palmer AC, Kim S, Veres A, Bershtein S, Kishony R. Evolution of Antibiotic Resistance through a Multi-Peaked Adaptive Landscape Biophysical Journal. 104: 660a. DOI: 10.1016/J.Bpj.2012.11.3644  0.518
2012 Skurnik D, Davis MR, Benedetti D, Moravec KL, Cywes-Bentley C, Roux D, Traficante DC, Walsh RL, Maira-Litràn T, Cassidy SK, Hermos CR, Martin TR, Thakkallapalli EL, Vargas SO, McAdam AJ, ... ... Kishony R, et al. Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection. The Journal of Infectious Diseases. 205: 1709-18. PMID 22448004 DOI: 10.1093/Infdis/Jis254  0.424
2012 Ernebjerg M, Kishony R. Distinct growth strategies of soil bacteria as revealed by large-scale colony tracking. Applied and Environmental Microbiology. 78: 1345-52. PMID 22194284 DOI: 10.1128/Aem.06585-11  0.314
2012 Toprak E, Veres A, Michel JB, Chait R, Hartl DL, Kishony R. Evolutionary paths to antibiotic resistance under dynamically sustained drug selection. Nature Genetics. 44: 101-5. PMID 22179135 DOI: 10.1038/Ng.1034  0.508
2012 Chait R, Vetsigian K, Kishony R. What counters antibiotic resistance in nature? Nature Chemical Biology. 8: 2-5. PMID 22173342 DOI: 10.1038/Nchembio.745  0.446
2011 Lieberman TD, Michel JB, Aingaran M, Potter-Bynoe G, Roux D, Davis MR, Skurnik D, Leiby N, LiPuma JJ, Goldberg JB, McAdam AJ, Priebe GP, Kishony R. Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes. Nature Genetics. 43: 1275-80. PMID 22081229 DOI: 10.1038/Ng.997  0.402
2011 Bush K, Courvalin P, Dantas G, Davies J, Eisenstein B, Huovinen P, Jacoby GA, Kishony R, Kreiswirth BN, Kutter E, Lerner SA, Levy S, Lewis K, Lomovskaya O, Miller JH, et al. Tackling antibiotic resistance. Nature Reviews. Microbiology. 9: 894-6. PMID 22048738 DOI: 10.1038/Nrmicro2693  0.43
2011 Vetsigian K, Jajoo R, Kishony R. Structure and evolution of Streptomyces interaction networks in soil and in silico. Plos Biology. 9: e1001184. PMID 22039352 DOI: 10.1371/Journal.Pbio.1001184  0.322
2011 Bollenbach T, Kishony R. Resolution of gene regulatory conflicts caused by combinations of antibiotics. Molecular Cell. 42: 413-25. PMID 21596308 DOI: 10.1016/J.Molcel.2011.04.016  0.331
2010 Chait R, Shrestha S, Shah AK, Michel JB, Kishony R. A differential drug screen for compounds that select against antibiotic resistance. Plos One. 5: e15179. PMID 21209699 DOI: 10.1371/Journal.Pone.0015179  0.45
2010 Torella JP, Chait R, Kishony R. Optimal drug synergy in antimicrobial treatments. Plos Computational Biology. 6: e1000796. PMID 20532210 DOI: 10.1371/Journal.Pcbi.1000796  0.437
2010 Palmer AC, Angelino E, Kishony R. Chemical decay of an antibiotic inverts selection for resistance. Nature Chemical Biology. 6: 244. PMID 20154670 DOI: 10.1038/Nchembio0310-244A  0.317
2010 Palmer AC, Angelino E, Kishony R. Chemical decay of an antibiotic inverts selection for resistance. Nature Chemical Biology. 6: 105-7. PMID 20081825 DOI: 10.1038/Nchembio.289  0.447
2009 Bollenbach T, Quan S, Chait R, Kishony R. Nonoptimal microbial response to antibiotics underlies suppressive drug interactions. Cell. 139: 707-18. PMID 19914165 DOI: 10.1016/J.Cell.2009.10.025  0.328
2009 Swoboda JG, Meredith TC, Campbell J, Brown S, Suzuki T, Bollenbach T, Malhowski AJ, Kishony R, Gilmore MS, Walker S. Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. Acs Chemical Biology. 4: 875-83. PMID 19689117 DOI: 10.1021/Cb900151K  0.352
2009 Yeh PJ, Hegreness MJ, Aiden AP, Kishony R. Drug interactions and the evolution of antibiotic resistance. Nature Reviews. Microbiology. 7: 460-6. PMID 19444248 DOI: 10.1038/Nrmicro2133  0.399
2008 Michel JB, Yeh PJ, Chait R, Moellering RC, Kishony R. Drug interactions modulate the potential for evolution of resistance. Proceedings of the National Academy of Sciences of the United States of America. 105: 14918-23. PMID 18815368 DOI: 10.1073/Pnas.0800944105  0.465
2008 Hegreness M, Shoresh N, Damian D, Hartl D, Kishony R. Accelerated evolution of resistance in multidrug environments. Proceedings of the National Academy of Sciences of the United States of America. 105: 13977-81. PMID 18779569 DOI: 10.1073/Pnas.0805965105  0.46
2008 Pearl S, Gabay C, Kishony R, Oppenheim A, Balaban NQ. Nongenetic individuality in the host-phage interaction. Plos Biology. 6: e120. PMID 18494559 DOI: 10.1371/Journal.Pbio.0060120  0.379
2008 Presser A, Elowitz MB, Kellis M, Kishony R. The evolutionary dynamics of the Saccharomyces cerevisiae protein interaction network after duplication. Proceedings of the National Academy of Sciences of the United States of America. 105: 950-4. PMID 18199840 DOI: 10.1073/Pnas.0707293105  0.565
2007 Chait R, Craney A, Kishony R. Antibiotic interactions that select against resistance. Nature. 446: 668-71. PMID 17410176 DOI: 10.1038/Nature05685  0.497
2007 Hegreness M, Kishony R. Analysis of genetic systems using experimental evolution and whole-genome sequencing. Genome Biology. 8: 201. PMID 17274841 DOI: 10.1186/Gb-2007-8-1-201  0.36
2006 Yeh P, Tschumi AI, Kishony R. Functional classification of drugs by properties of their pairwise interactions. Nature Genetics. 38: 489-94. PMID 16550172 DOI: 10.1038/Ng1755  0.337
2006 Hegreness M, Shoresh N, Hartl D, Kishony R. An equivalence principle for the incorporation of favorable mutations in asexual populations. Science (New York, N.Y.). 311: 1615-7. PMID 16543462 DOI: 10.1126/Science.1122469  0.38
2005 Kussell E, Kishony R, Balaban NQ, Leibler S. Bacterial persistence: a model of survival in changing environments. Genetics. 169: 1807-14. PMID 15687275 DOI: 10.1534/Genetics.104.035352  0.613
2005 Segrè D, Deluna A, Church GM, Kishony R. Modular epistasis in yeast metabolism. Nature Genetics. 37: 77-83. PMID 15592468 DOI: 10.1038/Ng1489  0.317
2003 Kishony R, Leibler S. Environmental stresses can alleviate the average deleterious effect of mutations. Journal of Biology. 2: 14. PMID 12775217 DOI: 10.1186/1475-4924-2-14  0.582
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