| Year |
Citation |
Score |
| 2023 |
Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, ... Robbins DJ, et al. The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. Nature Communications. 14: 6173. PMID 37798301 DOI: 10.1038/s41467-023-41836-z |
0.303 |
|
| 2023 |
Spencer ZT, Ng VH, Benchabane H, Siddiqui GS, Duwadi D, Maines B, Bryant JM, Schwarzkopf A, Yuan K, Kassel SN, Mishra A, Pimentel A, Lebensohn AM, Rohatgi R, Gerber SA, Robbins DJ, et al. The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6. Nature Communications. 14: 6174. PMID 37798281 DOI: 10.1038/s41467-023-41843-0 |
0.314 |
|
| 2023 |
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, ... Robbins DJ, et al. USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling. Science Signaling. 16: eabn8372. PMID 36749823 DOI: 10.1126/scisignal.abn8372 |
0.331 |
|
| 2022 |
Yang F, Wynn DT, Shen C, Ayad NG, Robbins DJ. Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer. Life (Basel, Switzerland). 12. PMID 36556332 DOI: 10.3390/life12121967 |
0.355 |
|
| 2022 |
Wynn DT, Rodriguez-Blanco J, Long J, Yang F, Shen C, Fei D, Tang HY, Hanson D, Robbins DJ. Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression. Neuro-Oncology Advances. 4: vdac144. PMID 36299796 DOI: 10.1093/noajnl/vdac144 |
0.321 |
|
| 2022 |
Yang F, Rodriguez-Blanco J, Long J, Swiderska-Syn M, Wynn DT, Li B, Shen C, Nayak A, Ban Y, Sun X, Suter RK, McCrea HJ, Capobianco AJ, Ayad NG, Robbins DJ. A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth. Molecular Cancer Research : McR. PMID 35925047 DOI: 10.1158/1541-7786.MCR-22-0182 |
0.348 |
|
| 2022 |
Shen C, Nayak A, Neitzel LR, Yang F, Li B, Williams CH, Hong CC, Ahmed Y, Lee E, Robbins DJ. The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon. The Journal of Biological Chemistry. 102227. PMID 35780831 DOI: 10.1016/j.jbc.2022.102227 |
0.307 |
|
| 2021 |
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, ... Robbins DJ, et al. The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling. Nature Communications. 12: 5263. PMID 34489457 DOI: 10.1038/s41467-021-25634-z |
0.369 |
|
| 2021 |
Alvarez-Trotta A, Guerrant W, Astudillo L, Lahiry M, Diluvio G, Shersher E, Kaneku H, Robbins DJ, Orton D, Capobianco AJ. Pharmacological disruption of the Notch1 transcriptional complex inhibits tumor growth by selectively targeting cancer stem cells. Cancer Research. PMID 33820800 DOI: 10.1158/0008-5472.CAN-20-3611 |
0.393 |
|
| 2020 |
Alvarez-Trotta A, Wang Z, Shersher E, Li B, Long J, Lohse I, Wahlestedt C, El-Rifai W, Robbins DJ, Capobianco AJ. The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling. Oncotarget. 11: 3174-3187. PMID 32913560 DOI: 10.18632/Oncotarget.27699 |
0.458 |
|
| 2020 |
Shen C, Nayak A, Melendez RA, Wynn DT, Jackson J, Lee E, Ahmed Y, Robbins DJ. Casein Kinase 1α as a Regulator of Wnt-Driven Cancer. International Journal of Molecular Sciences. 21. PMID 32824859 DOI: 10.3390/Ijms21165940 |
0.479 |
|
| 2020 |
Anthony CC, Robbins DJ, Ahmed Y, Lee E. Nuclear Regulation of Wnt/β-Catenin Signaling: It's a Complex Situation. Genes. 11. PMID 32759724 DOI: 10.3390/Genes11080886 |
0.399 |
|
| 2019 |
Shen C, Li B, Astudillo L, Deutscher MP, Cobb MH, Capobianco AJ, Lee E, Robbins DJ. The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (/) of CK1α. Biochemistry. PMID 31820934 DOI: 10.1021/Acs.Biochem.9B00891 |
0.388 |
|
| 2019 |
Samaranayake GJ, Troccoli CI, Zhang L, Huynh M, Jayaraj CJ, Ji D, McPherson L, Onishi Y, Nguyen DM, Robbins DJ, Karbaschi M, Cooke MS, Barrientos A, Kool ET, Rai P. The existence of MTH1-independent 8-oxodGTPase activity in cancer cells as a compensatory mechanism against on-target effects of MTH1 inhibitors. Molecular Cancer Therapeutics. PMID 31744893 DOI: 10.1158/1535-7163.Mct-19-0437 |
0.383 |
|
| 2019 |
McPherson LA, Troccoli CI, Ji D, Bowles AE, Gardiner ML, Mohsen MG, Nagathihalli NS, Nguyen DM, Robbins DJ, Merchant NB, Kool ET, Rai P, Ford JM. Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue. Dna Repair. 102644. PMID 31311767 DOI: 10.1016/J.Dnarep.2019.102644 |
0.391 |
|
| 2019 |
Lu H, Bhat AA, Peng D, Chen Z, Zhu S, Hong J, Maacha S, Yan J, Robbins DJ, Washington MK, Belkhiri A, El-Rifai W. APE1 upregulates MMP-14 via redox-sensitive ARF6-mediated recycling to promote cell invasion of esophageal adenocarcinoma. Cancer Research. PMID 31308045 DOI: 10.1158/0008-5472.Can-19-0237 |
0.321 |
|
| 2019 |
Penas C, Maloof ME, Stathias V, Long J, Tan SK, Mier J, Fang Y, Valdes C, Rodriguez-Blanco J, Chiang CM, Robbins DJ, Liebl DJ, Lee JK, Hatten ME, Clarke J, et al. Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis. Nature Communications. 10: 3028. PMID 31292434 DOI: 10.1038/S41467-019-10799-5 |
0.376 |
|
| 2019 |
Cabel CR, Alizadeh E, Robbins DJ, Ahmed Y, Lee E, Thorne CA. Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells. Developmental Cell. 49: 827-828. PMID 31211991 DOI: 10.1016/J.Devcel.2019.05.039 |
0.444 |
|
| 2019 |
Taylor R, Long J, Yoon JW, Childs R, Sylvestersen KB, Nielsen ML, Leong KF, Iannaccone S, Walterhouse DO, Robbins DJ, Iannaccone P. Regulation of GLI1 by cis DNA elements and epigenetic marks. Dna Repair. 79: 10-21. PMID 31085420 DOI: 10.1016/J.Dnarep.2019.04.011 |
0.377 |
|
| 2019 |
Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E. Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway. Mechanisms of Development. PMID 30904594 DOI: 10.1016/J.Mod.2019.03.002 |
0.455 |
|
| 2019 |
Lu H, Bhat AA, Peng D, Chen Z, Zhu S, Hong J, Maacha S, Robbins D, Belkhiri A, El-Rifai W. Abstract 157: APE1 upregulates MMP-14 to promote invasion of esophageal adenocarcinoma via redox-sensitive ARF6-mediated recycling Cancer Research. 79: 157-157. DOI: 10.1158/1538-7445.Am2019-157 |
0.343 |
|
| 2018 |
Robbins DJ, Rodriguez-Blanco J, Li B, Shen C, Orton D, Collins SA, Kasahara N, Ayad N, McCrea HJ, Roussel MF, Weiss WA, Capobianco AJ, Long J, Yang F. A CK1α activator penetrates the brain, and shows efficacy against drug-resistant metastatic medulloblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30487124 DOI: 10.1158/1078-0432.Ccr-18-1319 |
0.344 |
|
| 2018 |
Saito-Diaz K, Benchabane H, Tiwari A, Tian A, Li B, Thompson JJ, Hyde AS, Sawyer LM, Jodoin JN, Santos E, Lee LA, Coffey RJ, Beauchamp RD, Williams CS, Kenworthy AK, ... Robbins DJ, et al. APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway. Developmental Cell. 44: 566-581.e8. PMID 29533772 DOI: 10.1016/J.Devcel.2018.02.013 |
0.436 |
|
| 2018 |
Pei X, Chan H, Zhang L, Wang C, Robbins D, Capobianco T, Bai F. Abstract P2-08-01: Loss of function of Brca1 or Gata3 induces basal-like breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-08-01 |
0.371 |
|
| 2018 |
Tan SK, Penas C, Chiang C, Robbins D, Ayad N. Abstract 4138: CK1δ-BRD4 pathway as novel therapeutic target for SHH subtype of medulloblastoma Tumor Biology. DOI: 10.1158/1538-7445.Am2018-4138 |
0.334 |
|
| 2018 |
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss W, Rodriguez C, Mehrdad N, Nguyen D, Ayad N, Rai P, Capobianco A, Robbins D. MBRS-64. SURPRISING ROLE FOR WNT SIGNALING IN SONIC HEDGEHOG DRIVEN MEDULLOBLASTOMA Neuro-Oncology. 20: i142-i142. DOI: 10.1093/Neuonc/Noy059.508 |
0.413 |
|
| 2017 |
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss WA, Rodriguez C, Mehrdad N, Nguyen DM, Ayad NG, Rai P, Capobianco AJ, Robbins DJ. Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma. Oncogene. PMID 28714964 DOI: 10.1038/Onc.2017.232 |
0.438 |
|
| 2017 |
Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, ... ... Robbins DJ, et al. Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors. Science Signaling. 10. PMID 28655862 DOI: 10.1126/Scisignal.Aak9916 |
0.46 |
|
| 2017 |
Jin K, Zhou W, Han X, Wang Z, Li B, Jeffries S, Tao W, Robbins DJ, Capobianco AJ. p300-mediated acetylation of the Notch effector transcription factor Maml-1 recruits NACK to initiate Notch-dependent transcription. Cancer Research. PMID 28625977 DOI: 10.1158/0008-5472.Can-16-3156 |
0.36 |
|
| 2017 |
Han X, Ranganathan P, Tzimas C, Weaver KL, Jin K, Astudillo L, Zhou W, Zhu X, Li B, Robbins DJ, Capobianco AJ. Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex. Molecular Cancer Research : McR. PMID 28584023 DOI: 10.1158/1541-7786.Mcr-17-0241 |
0.326 |
|
| 2017 |
Scott A, Bai F, Chan HL, Liu S, Slingerland JM, Robbins DJ, Capobianco AJ, Pei XH. p16 loss rescues functional decline of Brca1-deficient mammary stem cells. Cell Cycle (Georgetown, Tex.). 0. PMID 28278054 DOI: 10.1080/15384101.2017.1295185 |
0.325 |
|
| 2017 |
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss W, Rodriguez C, Merhdad N, Nguyen D, Ayad N, Rai P, Capobianco A, Robbins DJ. PDTM-03. SURPRISING ROLE FOR WNT SIGNALING IN Trp53-MUTANT SHH MEDULLOBLASTOMA Neuro-Oncology. 19: vi190-vi190. DOI: 10.1093/Neuonc/Nox168.768 |
0.399 |
|
| 2016 |
Scott A, Bai F, Chan HL, Liu S, Ma J, Slingerland JM, Robbins DJ, Capobianco AJ, Pei XH. p16INK4a suppresses BRCA1-deficient mammary tumorigenesis. Oncotarget. PMID 27811360 DOI: 10.18632/Oncotarget.13015 |
0.342 |
|
| 2016 |
Liu S, Lam Chan H, Bai F, Ma J, Scott A, Robbins DJ, Capobianco AJ, Zhu P, Pei XH. Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis. Oncotarget. PMID 27588406 DOI: 10.18632/Oncotarget.11746 |
0.328 |
|
| 2016 |
Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. PMID 27210761 DOI: 10.1016/J.Celrep.2016.04.070 |
0.412 |
|
| 2016 |
Astudillo L, da Silva TG, Wang Z, Han X, Jin K, VanWye J, Zhu X, Weaver KL, Oashi T, Lopes PE, Orton D, Neitzel LR, Lee E, Landgraf R, Robbins DJ, et al. The small molecule IMR-1 inhibits the Notch transcriptional activation complex to suppress tumorigenesis. Cancer Research. PMID 27197169 DOI: 10.1158/0008-5472.Can-16-0061 |
0.438 |
|
| 2016 |
Castellanos J, Srinivasan S, Honnenahally K, Shi C, VanSaun M, Robbins D, Merchant N, Nagathihalli N. Abstract 2618: Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic cancer Cancer Research. 76: 2618-2618. DOI: 10.1158/1538-7445.Am2016-2618 |
0.472 |
|
| 2015 |
Li B, Giambelli C, Tang B, Winterbottom E, Long J, Jin K, Wang Z, Liang Fei D, Nguyen DM, Athar M, Wang B, Subbarayan PR, Wang L, Rai P, Ardalan B, ... ... Robbins DJ, et al. Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context Dependent Manner. Molecular Pharmacology. PMID 26573582 DOI: 10.1124/Mol.115.100867 |
0.476 |
|
| 2015 |
Long J, Winterbottom E, Robbins DJ. Sonic Hedgehog: a lipid speciated hormone? Oncotarget. 6: 19340-1. PMID 26305721 DOI: 10.18632/Oncotarget.4969 |
0.349 |
|
| 2015 |
Winterbottom EF, Fei DL, Koestler DC, Giambelli C, Wika E, Capobianco AJ, Lee E, Marsit CJ, Karagas MR, Robbins DJ. GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth. Ebiomedicine. 2: 536-43. PMID 26288817 DOI: 10.1016/J.Ebiom.2015.04.019 |
0.325 |
|
| 2015 |
Farzan SF, Robbins DJ. Quantitative Immunoblotting of Endogenous Hedgehog Pathway Components. Methods in Molecular Biology (Clifton, N.J.). 1322: 93-104. PMID 26179042 DOI: 10.1007/978-1-4939-2772-2_9 |
0.396 |
|
| 2015 |
Penas C, Govek EE, Fang Y, Ramachandran V, Daniel M, Wang W, Maloof ME, Rahaim RJ, Bibian M, Kawauchi D, Finkelstein D, Han JL, Long J, Li B, Robbins DJ, et al. Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis. Cell Reports. 11: 249-60. PMID 25843713 DOI: 10.1016/J.Celrep.2015.03.016 |
0.406 |
|
| 2015 |
Long J, Tokhunts R, Old WM, Houel S, Rodgriguez-Blanco J, Singh S, Schilling N, Capobianco AJ, Ahn NG, Robbins DJ. Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties. Cell Reports. 10: 1280-7. PMID 25732819 DOI: 10.1016/J.Celrep.2015.01.058 |
0.737 |
|
| 2015 |
Lindley LE, Curtis KM, Sanchez-Mejias A, Rieger ME, Robbins DJ, Briegel KJ. The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage. Development (Cambridge, England). 142: 893-904. PMID 25655704 DOI: 10.1242/Dev.110403 |
0.386 |
|
| 2015 |
Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG. Epigenetic pathways and glioblastoma treatment: insights from signaling cascades. Journal of Cellular Biochemistry. 116: 351-63. PMID 25290986 DOI: 10.1002/Jcb.24990 |
0.442 |
|
| 2015 |
Patel A, Burton DG, Halvorsen K, Balkan W, Reiner T, Perez-Stable C, Cohen A, Munoz A, Giribaldi MG, Singh S, Robbins DJ, Nguyen DM, Rai P. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. 34: 2586-96. PMID 25023700 DOI: 10.1038/Onc.2014.195 |
0.419 |
|
| 2015 |
Pei X, Bai F, Chan HL, Scott A, Smith MD, Fan C, Herschkowitz JI, Perou CM, Livingstone AS, Robbins DJ, Capobianco AJ. Abstract P4-05-01: Genetic analysis of the role of Brca1 in suppression of basal-like breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P4-05-01 |
0.377 |
|
| 2015 |
Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG. Editor's Choice: Epigenetic Pathways and Glioblastoma Treatment: Insights from Signaling Cascades Journal of Cellular Biochemistry. 116: iii. DOI: 10.1002/Jcb.25034 |
0.371 |
|
| 2014 |
Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. The Journal of Biological Chemistry. 289: 35494-502. PMID 25355313 DOI: 10.1074/Jbc.M114.595348 |
0.52 |
|
| 2014 |
Bai F, Chan HL, Scott A, Smith MD, Fan C, Herschkowitz JI, Perou CM, Livingstone AS, Robbins DJ, Capobianco AJ, Pei XH. BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development. Cancer Research. 74: 6161-72. PMID 25239453 DOI: 10.1158/0008-5472.Can-14-1119 |
0.417 |
|
| 2014 |
Wang Z, Da Silva TG, Jin K, Han X, Ranganathan P, Zhu X, Sanchez-Mejias A, Bai F, Li B, Fei DL, Weaver K, Carpio RV, Moscowitz AE, Koshenkov VP, Sanchez L, ... ... Robbins DJ, et al. Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma. Cancer Research. 74: 6364-74. PMID 25164006 DOI: 10.1158/0008-5472.Can-14-2051 |
0.457 |
|
| 2014 |
Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, Demarest RM, Tzimas C, Rice M, Vasquez-Del Carpio R, Dahmane N, ... Robbins DJ, et al. NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis. Cancer Research. 74: 4741-51. PMID 25038227 DOI: 10.1158/0008-5472.Can-14-1547 |
0.414 |
|
| 2014 |
Li B, Flaveny CA, Giambelli C, Fei DL, Han L, Hang BI, Bai F, Pei XH, Nose V, Burlingame O, Capobianco AJ, Orton D, Lee E, Robbins DJ. Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis. Plos One. 9: e101969. PMID 25003333 DOI: 10.1371/Journal.Pone.0101969 |
0.421 |
|
| 2014 |
Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, ... Robbins DJ, et al. Pyrvinium attenuates Hedgehog signaling downstream of smoothened. Cancer Research. 74: 4811-21. PMID 24994715 DOI: 10.1158/0008-5472.Can-14-0317 |
0.515 |
|
| 2014 |
Sverrisson EF, Zens MS, Fei DL, Andrews A, Schned A, Robbins D, Kelsey KT, Li H, DiRenzo J, Karagas MR, Seigne JD. Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer. Urologic Oncology. 32: 539-45. PMID 24856810 DOI: 10.1016/J.Urolonc.2014.03.006 |
0.414 |
|
| 2014 |
Busch AM, Galimberti F, Nehls KE, Roengvoraphoj M, Sekula D, Li B, Guo Y, Direnzo J, Fiering SN, Spinella MJ, Robbins DJ, Memoli VA, Freemantle SJ, Dmitrovsky E. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biology & Therapy. 15: 463-72. PMID 24496080 DOI: 10.4161/Cbt.27821 |
0.63 |
|
| 2014 |
You M, Varona-Santos J, Singh S, Robbins DJ, Savaraj N, Nguyen DM. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro. The Journal of Thoracic and Cardiovascular Surgery. 147: 508-16. PMID 24094913 DOI: 10.1016/J.Jtcvs.2013.08.035 |
0.451 |
|
| 2014 |
Patel A, Halvorsen K, Balkan W, Cohen A, Reiner T, Robbins D, Nguyen D, Rai P. Abstract B14: Human Mut T homolog 1 (MTH1) as a novel facilitator of KRAS-driven lung cancer Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B14 |
0.42 |
|
| 2014 |
Singh S, Nguyen DM, Capobianco AJ, Robbins DJ. Abstract 1951: Role of embryonic signaling pathways in lung cancer Cancer Research. 74: 1951-1951. DOI: 10.1158/1538-7445.Am2014-1951 |
0.511 |
|
| 2014 |
Rodriguez-Blanco J, Bin L, Martin V, Lee E, Rodriguez C, Capobianco A, Robbins DJ. SC-28 * NOVEL INHIBITORS ON HEDGEHOG PATHWAY TO PREVENT MEDULLOBLASTOMA RELAPSE Neuro-Oncology. 16: v203-v203. DOI: 10.1093/Neuonc/Nou275.28 |
0.433 |
|
| 2013 |
Srivastava RK, Li C, Chaudhary SC, Ballestas ME, Elmets CA, Robbins DJ, Matalon S, Deshane JS, Afaq F, Bickers DR, Athar M. Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption. Toxicology and Applied Pharmacology. 272: 879-87. PMID 23954561 DOI: 10.1016/J.Taap.2013.08.004 |
0.36 |
|
| 2013 |
Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, ... ... Robbins DJ, et al. The hedgehog processing pathway is required for NSCLC growth and survival. Oncogene. 32: 2335-45. PMID 22733134 DOI: 10.1038/Onc.2012.243 |
0.777 |
|
| 2013 |
Pochi SR, Doshi N, Han X, Wang Z, Capobianco A, Robbins D, Ardalan B. Abstract 4019: Regulatory role of Gli motifs in thymidylate synthase expression . Cancer Research. 73: 4019-4019. DOI: 10.1158/1538-7445.Am2013-4019 |
0.407 |
|
| 2013 |
You M, Santos JV, Robbins DJ, Savaraj N, Nguyen DM. Abstract 3246: Pharmacologic targeting of the Hedgehog (HH) signal transduction pathway significantly suppresses growth of malignant pleural mesothelioma (MPM) and non-small cell lung cancer (NSCLC) cells in vitro. Cancer Research. 73: 3246-3246. DOI: 10.1158/1538-7445.Am2013-3246 |
0.539 |
|
| 2013 |
Singh S, Robbins D, Capobianco AJ, Nguyen DM. Abstract 2645: Role of embryonic signaling pathways in lung cancer. Cancer Research. 73: 2645-2645. DOI: 10.1158/1538-7445.Am2013-2645 |
0.513 |
|
| 2012 |
Robbins DJ, Fei DL, Riobo NA. The Hedgehog signal transduction network. Science Signaling. 5: re6. PMID 23074268 DOI: 10.1126/Scisignal.2002906 |
0.436 |
|
| 2012 |
Galimberti F, Busch AM, Chinyengetere F, Ma T, Sekula D, Memoli VA, Dragnev KH, Liu F, Johnson KC, Guo Y, Freemantle SJ, Andrew AS, Greninger P, Robbins DJ, Settleman J, et al. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations. International Journal of Oncology. 41: 1751-61. PMID 22923130 DOI: 10.3892/Ijo.2012.1599 |
0.604 |
|
| 2012 |
Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, ... ... Robbins DJ, et al. Hedgehog signaling regulates bladder cancer growth and tumorigenicity. Cancer Research. 72: 4449-58. PMID 22815529 DOI: 10.1158/0008-5472.Can-11-4123 |
0.778 |
|
| 2012 |
Hang BI, Thorne CA, Robbins DJ, Huppert SS, Lee LA, Lee E. Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs. Bioorganic & Medicinal Chemistry. 20: 1869-77. PMID 22261025 DOI: 10.1016/J.Bmc.2011.12.044 |
0.352 |
|
| 2012 |
Wang Z, Ranganathan P, Koshenkov V, Bai F, Li B, Fei DL, Livingstone A, Franceschi D, Martell J, Robbins DJ, Capobianco AJ. Abstract 3336: The role of Notch signaling in esophageal adenocarcinoma Cancer Research. 72: 3336-3336. DOI: 10.1158/1538-7445.Am2012-3336 |
0.527 |
|
| 2012 |
Sverrisson E, Zens M, Fei D, Schned A, Robbins D, Kelsey K, Karagas M, Seigne J. 889 Clinicopathological Correlates Of Gli1 Expression In A Population Based Cohort Of Patients With Newly Diagnosed Bladder Cancer The Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.984 |
0.302 |
|
| 2011 |
Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, ... ... Robbins DJ, et al. A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Journal of Biomolecular Screening. 16: 995-1006. PMID 21859680 DOI: 10.1177/1087057111416657 |
0.407 |
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| 2011 |
Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ. Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Research. 71: 4454-63. PMID 21565978 DOI: 10.1158/0008-5472.Can-10-2313 |
0.776 |
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| 2011 |
Vasquez-Del Carpio R, Kaplan FM, Weaver KL, VanWye JD, Alves-Guerra MC, Robbins DJ, Capobianco AJ. Assembly of a Notch transcriptional activation complex requires multimerization. Molecular and Cellular Biology. 31: 1396-408. PMID 21245387 DOI: 10.1128/Mcb.00360-10 |
0.348 |
|
| 2011 |
Singh S, Wang Z, Giambelli C, Long J, Briegel KJ, Bejarano PA, Capobianco AJ, Robbins DJ. Abstract LB-430: Hedgehog signaling is required for the survival and tumorigenicity of cancer cells. Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-430 |
0.515 |
|
| 2011 |
Saeed A, Ngyuen D, Glassberg M, Koniaris L, Zimmers T, Robbins D, Lally B. The Influence of Latino Ethnicity on the Outcomes for Patients with Non-small Cell Lung Cancer: An Analysis of the Survival, Epidemiology, and End Results (SEER) Database International Journal of Radiation Oncology*Biology*Physics. 81: S597. DOI: 10.1016/J.Ijrobp.2011.06.1120 |
0.322 |
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| 2010 |
Xiao C, Ogle SA, Schumacher MA, Schilling N, Tokhunts RA, Orr-Asman MA, Miller ML, Robbins DJ, Hollande F, Zavros Y. Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G1252-65. PMID 20847300 DOI: 10.1152/Ajpgi.00512.2009 |
0.756 |
|
| 2010 |
Fei DL, Li H, Kozul CD, Black KE, Singh S, Gosse JA, DiRenzo J, Martin KA, Wang B, Hamilton JW, Karagas MR, Robbins DJ. Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors. Cancer Research. 70: 1981-8. PMID 20179202 DOI: 10.1158/0008-5472.Can-09-2898 |
0.356 |
|
| 2010 |
Farzan SF, Ogden SK, Robbins DJ. Quantitative insight into models of Hedgehog signal transduction Fly. 4: 141-144. PMID 20081354 DOI: 10.4161/Fly.4.2.10927 |
0.437 |
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| 2010 |
Tokhunts R, Singh S, Chu T, D'Angelo G, Baubet V, Goetz JA, Huang Z, Yuan Z, Ascano M, Zavros Y, Thérond PP, Kunes S, Dahmane N, Robbins DJ. The full-length unprocessed hedgehog protein is an active signaling molecule. The Journal of Biological Chemistry. 285: 2562-8. PMID 19920144 DOI: 10.1074/Jbc.M109.078626 |
0.755 |
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| 2009 |
Farzan SF, Stegman MA, Ogden SK, Ascano M, Black KE, Tacchelly O, Robbins DJ. A quantification of pathway components supports a novel model of Hedgehog signal transduction. The Journal of Biological Chemistry. 284: 28874-84. PMID 19717563 DOI: 10.1074/Jbc.M109.041608 |
0.347 |
|
| 2009 |
Singh S, Tokhunts R, Baubet V, Goetz JA, Huang ZJ, Schilling NS, Black KE, MacKenzie TA, Dahmane N, Robbins DJ. Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner. Human Genetics. 125: 95-103. PMID 19057928 DOI: 10.1007/S00439-008-0599-0 |
0.738 |
|
| 2008 |
Ogden SK, Fei DL, Schilling NS, Ahmed YF, Hwa J, Robbins DJ. G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling. Nature. 456: 967-70. PMID 18987629 DOI: 10.1038/Nature07459 |
0.321 |
|
| 2008 |
Farzan SF, Ascano M, Ogden SK, Sanial M, Brigui A, Plessis A, Robbins DJ. Costal2 functions as a kinesin-like protein in the hedgehog signal transduction pathway. Current Biology : Cb. 18: 1215-20. PMID 18691888 DOI: 10.1016/J.Cub.2008.07.026 |
0.332 |
|
| 2008 |
Li N, Singh S, Cherukuri P, Li H, Yuan Z, Ellisen LW, Wang B, Robbins D, DiRenzo J. Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells. Stem Cells (Dayton, Ohio). 26: 1253-64. PMID 18292212 DOI: 10.1634/Stemcells.2007-0691 |
0.311 |
|
| 2008 |
Tafe LJ, Robbins DJ, Fei DL, Srivastava A. M1953 GLI-1 Expression Suggests That Sonic Hedgehog Signaling May Be Involved in the Pathogenesis of Barrett's Esophagus Gastroenterology. 134: A-438. DOI: 10.1016/S0016-5085(08)62046-6 |
0.351 |
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| 2007 |
Robbins DJ, Hebrok M. Hedgehogs: la dolce vita. Workshop on Hedgehog-Gli Signaling in Cancer and Stem Cells. Embo Reports. 8: 451-5. PMID 17431408 DOI: 10.1038/Sj.Embor.7400959 |
0.304 |
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| 2007 |
Ma Y, Fiering S, Black C, Liu X, Yuan Z, Memoli VA, Robbins DJ, Bentley HA, Tsongalis GJ, Demidenko E, Freemantle SJ, Dmitrovsky E. Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas. Proceedings of the National Academy of Sciences of the United States of America. 104: 4089-94. PMID 17360482 DOI: 10.1073/Pnas.0606537104 |
0.537 |
|
| 2007 |
Yuan Z, Goetz JA, Singh S, Ogden SK, Petty WJ, Black CC, Memoli VA, Dmitrovsky E, Robbins DJ. Frequent requirement of hedgehog signaling in non-small cell lung carcinoma. Oncogene. 26: 1046-55. PMID 16909105 DOI: 10.1038/Sj.Onc.1209860 |
0.622 |
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| 2006 |
Ogden SK, Casso DJ, Ascano M, Yore MM, Kornberg TB, Robbins DJ. Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms. The Journal of Biological Chemistry. 281: 7237-43. PMID 16423832 DOI: 10.1074/Jbc.M510169200 |
0.349 |
|
| 2005 |
Robbins D, Goetz J, Yuan Z, Stegman M. Inhibitors of the Hedgehog Signal Transduction Pathway Current Cancer Therapy Reviews. 1: 277-288. DOI: 10.2174/157339405774574243 |
0.408 |
|
| 2004 |
Ogden SK, Ascano M, Stegman MA, Robbins DJ. Regulation of Hedgehog signaling: a complex story. Biochemical Pharmacology. 67: 805-14. PMID 15104233 DOI: 10.1016/J.Bcp.2004.01.002 |
0.323 |
|
| 2003 |
Ogden SK, Ascano M, Stegman MA, Suber LM, Hooper JE, Robbins DJ. Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2. Current Biology : Cb. 13: 1998-2003. PMID 14614827 DOI: 10.1016/J.Cub.2003.10.004 |
0.364 |
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| 2003 |
Krebs O, Schreiner CM, Scott WJ, Bell SM, Robbins DJ, Goetz JA, Alt H, Hawes N, Wolf E, Favor J. Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud. Development (Cambridge, England). 130: 6037-47. PMID 14597572 DOI: 10.1242/Dev.00861 |
0.347 |
|
| 2002 |
Alvarez J, Sohn P, Zeng X, Doetschman T, Robbins DJ, Serra R. TGFbeta2 mediates the effects of hedgehog on hypertrophic differentiation and PTHrP expression. Development (Cambridge, England). 129: 1913-24. PMID 11934857 |
0.313 |
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