Jason Carroll, Ph.D. - Publications

Affiliations: 
Cambridge Research Institute Cancer Research UK, Belfast, Northern Ireland, United Kingdom 

161 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ramachandran R, Ibragimova S, Woods LM, AlHouqani T, Gomez RL, Simeoni F, Hachim MY, Somervaille TCP, Philpott A, Carroll JS, Ali FR. Conserved role of FOXC1 in TNBC is parallel to FOXA1 in ER+ breast cancer. Iscience. 27: 110500. PMID 39171293 DOI: 10.1016/j.isci.2024.110500  0.471
2024 Li Z, Chen F, Chen L, Liu J, Tseng D, Hadi F, Omarjee S, Kishore K, Kent J, Kirkpatrick J, D'Santos C, Lawson M, Gertz J, Sikora MJ, McDonnell DP, ... Carroll JS, et al. EstroGene2.0: A multi-omic database of response to estrogens, ER-modulators, and resistance to endocrine therapies in breast cancer. Biorxiv : the Preprint Server For Biology. PMID 39005294 DOI: 10.1101/2024.06.28.601163  0.405
2024 Hosseinzadeh L, Kikhtyak Z, Laven-Law G, Pederson SM, Puiu CG, D'Santos CS, Lim E, Carroll JS, Tilley WD, Dwyer AR, Hickey TE. The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer. Genome Biology. 25: 44. PMID 38317241 DOI: 10.1186/s13059-023-03161-y  0.453
2023 Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AAB, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, ... ... Carroll JS, et al. Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. Elife. 12. PMID 37551662 DOI: 10.7554/eLife.90408  0.356
2023 Li Z, Li T, Yates ME, Wu Y, Ferber A, Chen L, Brown DD, Carroll JS, Sikora MJ, Tseng GC, Oesterreich S, Lee AV. The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer. Cancer Research. PMID 37272757 DOI: 10.1158/0008-5472.CAN-23-0539  0.419
2023 Wu Y, Li Z, Wedn AM, Casey AN, Brown D, Rao SV, Omarjee S, Hooda J, Carroll JS, Gertz J, Atkinson JM, Lee AV, Oesterreich S. FOXA1 reprogramming dictates retinoid X receptor response in ESR1 mutant breast cancer. Molecular Cancer Research : McR. PMID 36930833 DOI: 10.1158/1541-7786.MCR-22-0516  0.447
2023 Li Z, Li T, Yates ME, Wu Y, Ferber A, Chen L, Brown DD, Carroll JS, Sikora MJ, Tseng GC, Oesterreich S, Lee AV. EstroGene database reveals diverse temporal, context-dependent and directional estrogen receptor regulomes in breast cancer. Biorxiv : the Preprint Server For Biology. PMID 36778377 DOI: 10.1101/2023.01.30.526388  0.431
2022 Alizadeh-Ghodsi M, Owen KL, Townley SL, Zanker D, Rollin SPG, Hanson AR, Shrestha R, Toubia J, Gargett T, Chernukhin I, Luu J, Cowley KJ, Clark A, Carroll JS, Simpson KJ, et al. Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer. Cancer Research Communications. 2: 706-724. PMID 36923279 DOI: 10.1158/2767-9764.CRC-21-0139  0.305
2022 Parkinson LM, Gillen SL, Woods LM, Chaytor L, Marcos D, Ali FR, Carroll JS, Philpott A. The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma. Frontiers in Cell and Developmental Biology. 10: 942579. PMID 36263020 DOI: 10.3389/fcell.2022.942579  0.323
2022 Bahl S, Carroll JS, Lupien M. Chromatin Variants Reveal the Genetic Determinants of Oncogenesis in Breast Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 36041880 DOI: 10.1101/cshperspect.a041322  0.612
2022 Aspros KGM, Carter JM, Hoskin TL, Suman VJ, Subramaniam M, Emch MJ, Ye Z, Sun Z, Sinnwell JP, Thompson KJ, Tang X, Rodman EPB, Wang X, Nelson AW, Chernukhin I, ... ... Carroll JS, et al. Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer. Npj Breast Cancer. 8: 20. PMID 35177654 DOI: 10.1038/s41523-022-00387-0  0.408
2022 Li Z, Wu Y, Yates ME, Tasdemir N, Bahreini A, Chen J, Levine KM, Priedigkeit NM, Nasrazadani A, Ali S, Buluwela L, Arnesen S, Gertz J, Richer JK, Troness B, ... ... Carroll JS, et al. Hotspot ESR1 mutations are multimodal and contextual modulators of breast cancer metastasis. Cancer Research. PMID 35078818 DOI: 10.1158/0008-5472.CAN-21-2576  0.403
2021 Che M, Chaturvedi A, Munro SA, Pitzen SP, Ling A, Zhang W, Mentzer J, Ku SY, Puca L, Zhu Y, Bergman AM, Severson TM, Forster C, Liu Y, Hildebrand J, ... ... Carroll JS, et al. Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer. Nature Communications. 12: 6377. PMID 34737261 DOI: 10.1038/s41467-021-26612-1  0.314
2021 Broome R, Chernukhin I, Jamieson S, Kishore K, Papachristou EK, Mao SQ, Tejedo CG, Mahtey A, Theodorou V, Groen AJ, D'Santos C, Balasubramanian S, Farcas AM, Siersbæk R, Carroll JS. TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions. Cell Reports. 34: 108776. PMID 33626359 DOI: 10.1016/j.celrep.2021.108776  0.437
2021 Holliday H, Roden D, Junankar S, Wu SZ, Baker LA, Krisp C, Chan CL, McFarland A, Skhinas JN, Cox TR, Pal B, Huntington ND, Ormandy CJ, Carroll JS, Visvader J, et al. Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB. Iscience. 24: 102072. PMID 33554073 DOI: 10.1016/j.isci.2021.102072  0.318
2021 Hickey TE, Selth LA, Chia KM, Laven-Law G, Milioli HH, Roden D, Jindal S, Hui M, Finlay-Schultz J, Ebrahimie E, Birrell SN, Stelloo S, Iggo R, Alexandrou S, Caldon CE, ... ... Carroll JS, et al. The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer. Nature Medicine. PMID 33462444 DOI: 10.1038/s41591-020-01168-7  0.434
2021 Varešlija D, Ward E, Purcell SP, Cosgrove NS, Cocchiglia S, O'Halloran PJ, Charmsaz S, Bane FT, Brett FM, Farrell M, Cryan J, Beausang A, Hudson L, Turnbul AK, Dixon JM, ... ... Carroll JS, et al. Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype. Oncogene. PMID 33420368 DOI: 10.1038/s41388-020-01606-3  0.477
2020 Farcas AM, Nagarajan S, Cosulich S, Carroll JS. Genome-wide estrogen receptor activity in breast cancer. Endocrinology. PMID 33284960 DOI: 10.1210/endocr/bqaa224  0.46
2020 Giannoudis A, Malki MI, Rudraraju B, Mohhamed H, Menon S, Liloglou T, Ali S, Carroll JS, Palmieri C. Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer. Breast Cancer Research : Bcr. 22: 126. PMID 33198803 DOI: 10.1186/s13058-020-01359-7  0.449
2020 Ali FR, Marcos D, Chernukhin I, Woods LM, Parkinson LM, Wylie LA, Papkovskaia TD, Davies JD, Carroll JS, Philpott A. Dephosphorylation of the proneural transcription factor ASCL1 re-engages a latent post-mitotic differentiation programme in neuroblastoma. Molecular Cancer Research : McR. PMID 33046535 DOI: 10.1158/1541-7786.MCR-20-0693  0.303
2020 Wang S, Somisetty VS, Bai B, Chernukhin I, Niskanen H, Kaikkonen MU, Bellet M, Carroll JS, Hurtado A. The proapoptotic gene interferon regulatory factor-1 mediates the antiproliferative outcome of paired box 2 gene and tamoxifen. Oncogene. PMID 32843722 DOI: 10.1038/s41388-020-01435-4  0.443
2020 Siersbæk R, Scabia V, Nagarajan S, Chernukhin I, Papachristou EK, Broome R, Johnston SJ, Joosten SEP, Green AR, Kumar S, Jones J, Omarjee S, Alvarez-Fernandez R, Glont S, Aitken SJ, ... ... Carroll JS, et al. IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis. Cancer Cell. PMID 32679107 DOI: 10.1016/j.ccell.2020.06.007  0.345
2020 Hruschka N, Kalisz M, Subijana M, Graña-Castro O, Del Cano-Ochoa F, Brunet LP, Chernukhin I, Sagrera A, De Reynies A, Kloesch B, Chin SF, Burgués O, Andreu D, Bermejo B, Cejalvo JM, ... ... Carroll JS, et al. The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver. Oncogene. PMID 32587399 DOI: 10.1038/S41388-020-1376-3  0.406
2020 Baker LA, Holliday H, Roden D, Krisp C, Wu SZ, Junankar S, Serandour AA, Mohammed H, Nair R, Sankaranarayanan G, Law AMK, McFarland A, Simpson PT, Lakhani S, Dodson E, ... ... Carroll JS, et al. Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer. Breast Cancer Research : Bcr. 22: 63. PMID 32527287 DOI: 10.1186/S13058-020-01306-6  0.389
2020 Shu S, Wu HJ, Ge JY, Zeid R, Harris IS, Jovanović B, Murphy K, Wang B, Qiu X, Endress JE, Reyes J, Lim K, Font-Tello A, Syamala S, Xiao T, ... ... Carroll JS, et al. Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. Molecular Cell. PMID 32416067 DOI: 10.1016/J.Molcel.2020.04.027  0.544
2020 Nagarajan S, Rao SV, Sutton J, Cheeseman D, Dunn S, Papachristou EK, Prada JG, Couturier DL, Kumar S, Kishore K, Chilamakuri CSR, Glont SE, Goode EA, Brodie C, Guppy N, ... ... Carroll JS, et al. Author Correction: ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response. Nature Genetics. PMID 32005967 DOI: 10.1038/S41588-020-0582-9  0.308
2020 Nagarajan S, Rao SV, Sutton J, Cheeseman D, Dunn S, Papachristou EK, Prada JG, Couturier DL, Kumar S, Kishore K, Chilamakuri CSR, Glont SE, Archer Goode E, Brodie C, Guppy N, ... ... Carroll JS, et al. ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response. Nature Genetics. PMID 31913353 DOI: 10.1038/S41588-019-0541-5  0.421
2020 Fachal L, Aschard H, Beesley J, Barnes DR, Allen J, Kar S, Pooley KA, Dennis J, Michailidou K, Turman C, Soucy P, Lemaçon A, Lush M, Tyrer JP, Ghoussaini M, ... ... Carroll JS, et al. Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics. PMID 31911677 DOI: 10.1038/s41588-019-0537-1  0.36
2020 Piggin CL, Roden DL, Law AMK, Molloy MP, Krisp C, Swarbrick A, Naylor MJ, Kalyuga M, Kaplan W, Oakes SR, Gallego-Ortega D, Clark SJ, Carroll JS, Bartonicek N, Ormandy CJ. ELF5 modulates the estrogen receptor cistrome in breast cancer. Plos Genetics. 16: e1008531. PMID 31895944 DOI: 10.1371/journal.pgen.1008531  0.434
2020 Zeng YA, Carroll J, Borniger J. Decision letter: Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531 Elife. DOI: 10.7554/Elife.56913.Sa1  0.399
2020 Hickey TE, Selth L, Chia KM, Milioli H, Roden D, Laven-Law G, Jindal S, Hui M, Ebrahimie E, birrell S, Stelloo S, Caldon E, Findlay-Schultz J, Abdel_Fatah T, Ellis I, ... ... Carroll JS, et al. OR05-06 The Androgen Receptor Is a Tumour Suppressor in Estrogen Receptor Positive Breast Cancer Journal of the Endocrine Society. 4. DOI: 10.1210/jendso/bvaa046.982  0.46
2020 Li Z, Levine KM, Arneson S, Berrett KC, Priedigkeit NM, Bahreini A, Chen J, Zhu L, Carroll JS, Tseng GC, Lucas PC, Atkinson JM, Gertz J, Lee AV, Oesterreich S. Abstract 4917: Estrogen receptor D538G mutation promotes cell migration via hyperactivation of Wnt signaling pathway Cancer Research. 80: 4917-4917. DOI: 10.1158/1538-7445.Am2020-4917  0.36
2019 Redmond AM, Omarjee S, Chernukhin I, Le Romancer M, Carroll JS. Analysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation. Plos One. 14: e0225180. PMID 31747426 DOI: 10.1371/journal.pone.0225180  0.48
2019 Peluffo G, Subedee A, Harper NW, Kingston N, Jovanović B, Flores F, Stevens LE, Beca F, Trinh A, Reddy Chilamakuri CS, Papachristou EK, Murphy K, Su Y, Marusyk A, D'Santos CS, ... ... Carroll JS, et al. EN1 is a transcriptional dependency in triple-negative breast cancer associated with brain metastasis. Cancer Research. PMID 31239270 DOI: 10.1158/0008-5472.Can-18-3264  0.455
2019 Glont SE, Papachristou EK, Sawle A, Holmes KA, Carroll JS, Siersbaek R. Identification of ChIP-seq and RIME grade antibodies for Estrogen Receptor alpha. Plos One. 14: e0215340. PMID 30970003 DOI: 10.1371/journal.pone.0215340  0.345
2019 Goodman ML, Trinca GM, Walter KR, Papachristou EK, D'Santos CS, Li T, Liu Q, Lai Z, Chalise P, Madan R, Fan F, Markiewicz MA, Jin VX, Carroll JS, Hagan CR. Progesterone Receptor Attenuates STAT1-Mediated IFN Signaling in Breast Cancer. Journal of Immunology (Baltimore, Md. : 1950). PMID 30936295 DOI: 10.4049/Jimmunol.1801152  0.392
2019 Glont SE, Chernukhin I, Carroll JS. Comprehensive Genomic Analysis Reveals that the Pioneering Function of FOXA1 Is Independent of Hormonal Signaling. Cell Reports. 26: 2558-2565.e3. PMID 30840881 DOI: 10.1016/j.celrep.2019.02.036  0.408
2019 Aspros K, Nelson A, Ye Z, Sun Z, Chernukhin I, Carroll J, Ingle J, Goetz M, Hawse J. Abstract P5-05-03: Estrogen receptor beta elicits anti-cancer effects in triple negative breast cancer through suppression of NFκB signaling Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P5-05-03  0.556
2019 Li Z, Bahreini A, Levine K, Wang P, Tasdemir N, Montanez M, Sundd P, Wallace C, Watkins S, Chu D, Park B, Hou W, Zhu L, Tseng G, Carroll J, et al. Abstract P2-01-09: ESR1 mutations drive breast cancer metastasis by context-dependent alterations in adhesive and migratory properties Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P2-01-09  0.428
2019 Kumar S, Benson J, McIntosh S, King P, Dougall G, Kateb A, Vallier A, Jones L, Qian W, Provenzano E, Caldas C, Pantziarka P, Carroll J, Baird R. Abstract OT1-01-07: PIONEER- Pre-operative wIndOw study of letrozole plus PR agonist megestrol acetate versus letrozole aloNE in post-menopausal patients with ER-positive breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Ot1-01-07  0.459
2018 Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio AG, Sérandour AA, Dorsheimer L, Chalmel F, Carroll JS, Zörnig M, Rieger MA, Delalande O, Salbert G, Galibert MD, Gandemer V, et al. Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation. Nucleic Acids Research. 46: 11214-11228. PMID 30500954 DOI: 10.1093/nar/gky756  0.308
2018 Reese JM, Bruinsma ES, Nelson AW, Chernukhin I, Carroll JS, Li Y, Subramaniam M, Suman VJ, Negron V, Monroe DG, Ingle JN, Goetz MP, Hawse JR. ERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30257941 DOI: 10.1073/Pnas.1807751115  0.409
2018 Siersbæk R, Kumar S, Carroll JS. Signaling pathways and steroid receptors modulating estrogen receptor α function in breast cancer. Genes & Development. 32: 1141-1154. PMID 30181360 DOI: 10.1101/gad.316646.118  0.375
2018 Rouhimoghadam M, Safarian S, Carroll JS, Sheibani N, Bidkhori G. Tamoxifen-Induced Apoptosis of MCF-7 Cells via GPR30/PI3K/MAPKs Interactions: Verification by ODE Modeling and RNA Sequencing. Frontiers in Physiology. 9: 907. PMID 30050469 DOI: 10.3389/Fphys.2018.00907  0.446
2018 Serandour AA, Mohammed H, Miremadi A, Mulder KW, Carroll JS. TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers. Oncogene. PMID 29895970 DOI: 10.1038/S41388-018-0312-2  0.558
2018 Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, ... ... Carroll J, et al. Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications. 9: 16193. PMID 29633761 DOI: 10.1038/Ncomms16193  0.629
2018 Michaloglou C, Crafter C, Siersbæk R, Delpuech O, Curwen JO, Carnevalli LS, Staniszewska AD, Polanska UM, Cheraghchi-Bashi A, Lawson M, Chernukhin I, McEwen R, Carroll JS, Cosulich SC. Combined inhibition of mTOR and CDK4/6 is required for optimal blockade of E2F function and long term growth inhibition in estrogen receptor positive breast cancer. Molecular Cancer Therapeutics. PMID 29483206 DOI: 10.1158/1535-7163.MCT-17-0537  0.398
2018 Browne AL, Charmsaz S, Varešlija D, Fagan A, Cosgrove N, Cocchiglia S, Purcell S, Ward E, Bane F, Hudson L, Hill AD, Carroll JS, Redmond AM, Young LS. Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer. Oncogene. PMID 29367763 DOI: 10.1038/s41388-017-0042-x  0.415
2018 Oelmann E, Michaloglou C, Crafter C, Siersbaek R, Delpuech O, Curven J, Carnevalli L, Staniszweska A, Polanska U, Cheraghchi-Bashi A, Lawson M, Chernukhin I, McEwen R, Carroll J, Cosulich S. Abstract PD4-04: Combined inhibition of mTOR and CDK4/6 is required for optimal blockade of E2F function and long term growth inhibition in estrogen receptor positive breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-Pd4-04  0.411
2018 Goodman M, Trinca G, Walter K, Papachristou E, D'Santos C, Li T, Liu Q, Lai Z, Chalise P, Madan R, Jin V, Carroll J, Hagan C. Abstract 1800: Progesterone receptor attenuates STAT1-mediated interferon signaling in breast cancer Cancer Research. 78: 1800-1800. DOI: 10.1158/1538-7445.Am2018-1800  0.51
2017 Martin LA, Ribas R, Simigdala N, Schuster E, Pancholi S, Tenev T, Gellert P, Buluwela L, Harrod A, Thornhill A, Nikitorowicz-Buniak J, Bhamra A, Turgeon MO, Poulogiannis G, Gao Q, ... ... Carroll J, et al. Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance. Nature Communications. 8: 1865. PMID 29192207 DOI: 10.1038/S41467-017-01864-Y  0.389
2017 Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, Kar S, Lemaçon A, Soucy P, Glubb D, Rostamianfar A, Bolla MK, Wang Q, Tyrer J, Dicks E, Lee A, ... ... Carroll JS, et al. Association analysis identifies 65 new breast cancer risk loci. Nature. PMID 29059683 DOI: 10.1038/Nature24284  0.4
2017 Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Fossat N, Radziewic T, Liu K, Ratnayaka I, ... ... Carroll J, et al. Correction: SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development doi: 10.1242/dev.146241. Development (Cambridge, England). 144: 3847-3848. PMID 29042478 DOI: 10.1242/Dev.159715  0.339
2017 Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, ... Carroll J, et al. SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development (Cambridge, England). PMID 28619820 DOI: 10.1242/Dev.146241  0.411
2017 Jeselsohn R, Cornwell M, Pun M, Buchwalter G, Nguyen M, Bango C, Huang Y, Kuang Y, Paweletz C, Fu X, Nardone A, De Angelis C, Detre S, Dodson A, Mohammed H, ... Carroll JS, et al. Embryonic transcription factor SOX9 drives breast cancer endocrine resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 28507152 DOI: 10.1073/Pnas.1620993114  0.739
2017 Paltoglou S, Das R, Townley SL, Hickey T, Tarulli G, Coutinho I, Fernandes RC, Hanson A, Denis I, Carroll J, Dehm SM, Raj GV, Plymate S, Tilley WD, Selth LA. Novel androgen receptor co-regulator GRHL2 exerts both oncogenic and anti-metastatic functions in prostate cancer. Cancer Research. PMID 28473532 DOI: 10.1158/0008-5472.Can-16-1616  0.322
2017 Dubois-Chevalier J, Dubois V, Dehondt H, Mazrooei P, Mazuy C, Sérandour AA, Gheeraert C, Penderia G, Baugé E, Derudas B, Hennuyer N, Paumelle R, Marot G, Carroll JS, Lupien M, et al. The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions. Genome Research. PMID 28400425 DOI: 10.1101/Gr.217075.116  0.567
2017 Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AA, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, ... ... Carroll JS, et al. Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. Elife. 6. PMID 28137359 DOI: 10.7554/Elife.21221  0.338
2017 Reese J, Bruinsma E, Suman V, Nelson A, Chernukhin I, Carroll J, Ingle J, Goetz M, Hawse J. Abstract P3-07-20: Biological functions of ERβ in triple negative breast cancer and its utility as a novel therapeutic drug target Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P3-07-20  0.43
2017 Kumar S, Dougall G, Vallier A, Jones L, Qian W, Provenzano E, Caldas C, Pantziarka P, Carroll J, Baird R. PIONEER- Pre-operative wIndOw study of letrozole plus PR agonist megestrol acetate versus letrozole aloNE in post-menopausal patients with ER-positive breast cancer Annals of Oncology. 28: v65-v66. DOI: 10.1093/ANNONC/MDX362.062  0.351
2016 Jozwik KM, Chernukhin I, Serandour AA, Nagarajan S, Carroll JS. FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3. Cell Reports. 17: 2715-2723. PMID 27926873 DOI: 10.1016/j.celrep.2016.11.028  0.361
2016 Nelson AW, Groen AJ, Miller JL, Warren AY, Holmes KA, Tarulli GA, Tilley WD, Katzenellenbogen BS, Hawse JR, Gnanapragasam VJ, Carroll JS. Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity. Molecular and Cellular Endocrinology. PMID 27889472 DOI: 10.1016/J.Mce.2016.11.016  0.328
2016 Carroll JS, Hickey TE, Tarulli GA, Williams M, Tilley WD. Deciphering the divergent roles of progestogens in breast cancer. Nature Reviews. Cancer. PMID 27885264 DOI: 10.1038/nrc.2016.116  0.394
2016 Hu DG, Selth L, Tarulli G, Meech R, Chanawong A, Wijayakumara D, Russell R, Caldas C, Robinson JL, Carroll J, Tilley WD, MacKenzie PI, Hickey T. Androgen and estrogen receptors in breast cancer co-regulate human UDP-glucuronosyltransferases 2B15 and 2B17. Cancer Research. PMID 27496708 DOI: 10.1158/0008-5472.CAN-15-3372  0.492
2016 Carroll JS. Mechanisms of oestrogen receptor (ER) gene regulation in breast cancer. European Journal of Endocrinology / European Federation of Endocrine Societies. 175: R41-9. PMID 26884552 DOI: 10.1530/Eje-16-0124  0.555
2016 Shu S, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M, Jin Huh S, Liang Y, Ryan J, Doherty E, Mohammed H, Guo H, Stover DG, Ekram MB, ... ... Carroll JS, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. PMID 26735014 DOI: 10.1038/Nature16508  0.556
2016 Holmes KA, Brown GD, Carroll JS. Chromatin Immunoprecipitation-Sequencing (ChIP-seq) for Mapping of Estrogen Receptor-Chromatin Interactions in Breast Cancer. Methods in Molecular Biology (Clifton, N.J.). 1366: 79-98. PMID 26585129 DOI: 10.1007/978-1-4939-3127-9_8  0.392
2016 Shu S, Lin C, He HH, Witwicki R, Roberts J, Tabassum D, Liang Y, Ekram M, Doherty E, Brown J, Mohammed H, D'Santos C, McKeown M, Ott C, Qi J, ... ... Carroll J, et al. Abstract B16: Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-B16  0.648
2016 Palmieri C, Rudraraju B, Giannoudis A, Moore D, Shaw J, Chan S, Ellis I, Caldas C, Coombes R, Carroll J, Ali S, Abdel-Fatah T. Abstract P5-08-17: A study of c-Jun N-terminal kinase (JNK) and c-Jun as biomarkers in early breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P5-08-17  0.358
2016 Asim M, Massie C, Warren A, Luko K, Chohan B, Menon S, Baridi A, Orafidiya F, Zhao W, Escriu C, Mohammed H, D’Santos C, Yang X, Taylor C, Qureshi A, ... ... Carroll J, et al. Abstract LB-003: Androgen-regulated proteome reveals a therapeutically relevant androgen receptor coactivator target in prostate cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-003  0.404
2016 Trinca G, Goodman M, Workman L, Carroll J, D’Santos C, Slawson C, Hagan CR. Abstract 1818: Coregulation of progesterone receptor and O-GlcNAc in breast cancer Cancer Research. 76: 1818-1818. DOI: 10.1158/1538-7445.Am2016-1818  0.48
2016 Carroll J. Understanding estrogen receptor transcription in breast cancer European Journal of Cancer. 61: S9. DOI: 10.1016/S0959-8049(16)61019-5  0.445
2015 Baird RD, Carroll JS. Understanding Oestrogen Receptor Function in Breast Cancer and its Interaction with the Progesterone Receptor. New Preclinical Findings and their Clinical Implications. Clinical Oncology (Royal College of Radiologists (Great Britain)). PMID 26548499 DOI: 10.1016/j.clon.2015.10.005  0.336
2015 D'Santos C, Taylor C, Carroll JS, Mohammed H. RIME proteomics of estrogen and progesterone receptors in breast cancer. Data in Brief. 5: 276-80. PMID 26543891 DOI: 10.1016/j.dib.2015.08.019  0.433
2015 Periyasamy M, Patel H, Lai CF, Nguyen VT, Nevedomskaya E, Harrod A, Russell R, Remenyi J, Ochocka AM, Thomas RS, Fuller-Pace F, Győrffy B, Caldas C, Navaratnam N, Carroll JS, et al. APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer. Cell Reports. 13: 108-21. PMID 26411678 DOI: 10.1016/J.Celrep.2015.08.066  0.466
2015 Zwart W, Flach KD, Rudraraju B, Abdel-Fatah TM, Gojis O, Moore D, Nevedomskaya E, Opdam M, Droog M, Hofland I, Chan SY, Shaw J, Ellis IO, Coombes RC, Carroll JS, et al. SRC3 phosphorylation at Serine 543 is a positive independent prognostic factor in ER positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26369632 DOI: 10.1158/1078-0432.CCR-14-3277  0.43
2015 Mohammed H, Russell IA, Stark R, Rueda OM, Hickey TE, Tarulli GA, Serandour AA, Birrell SN, Bruna A, Saadi A, Menon S, Hadfield J, Pugh M, Raj GV, Brown GD, ... ... Carroll JS, et al. Corrigendum: Progesterone receptor modulates ERα action in breast cancer. Nature. 526: 144. PMID 26245370 DOI: 10.1038/Nature14959  0.338
2015 Mohammed H, Russell IA, Stark R, Rueda OM, Hickey TE, Tarulli GA, Serandour AA, Serandour AA, Birrell SN, Bruna A, Saadi A, Menon S, Hadfield J, Pugh M, Raj GV, ... ... Carroll JS, et al. Progesterone receptor modulates ERα action in breast cancer. Nature. 523: 313-7. PMID 26153859 DOI: 10.1038/Nature14583  0.461
2015 Johnston SJ, Carroll JS. Transcription factors and chromatin proteins as therapeutic targets in cancer. Biochimica Et Biophysica Acta. 1855: 183-192. PMID 25721328 DOI: 10.1016/j.bbcan.2015.02.002  0.325
2015 Redmond AM, Byrne C, Bane FT, Brown GD, Tibbitts P, O'Brien K, Hill AD, Carroll JS, Young LS. Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells. Oncogene. 34: 3871-80. PMID 25284587 DOI: 10.1038/onc.2014.323  0.454
2015 roffey j, Lejeune A, Barnard M, Stock J, Wong AC, McKelvie J, Holmes K, Carroll J, Myatt S. Abstract LB-125: The identification of FOXA1/ERα pathway modulators for the treatment of hormone-based therapy resistant breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-125  0.553
2015 McNair C, Goodwin J, Augello M, Urbanucci A, Schiewer M, Comstock C, Ertel A, Wang L, Wang Q, Mills I, Li W, Carroll J, Knudsen K. Abstract 1844: Genome wide analysis of AR-cell cycle interplay reveals novel functions in cancer Cancer Research. 75: 1844-1844. DOI: 10.1158/1538-7445.Am2015-1844  0.411
2015 Mohammed H, Russell IA, Stark R, Rueda OM, Hickey TE, Tarulli GA, Serandour AAA, Birrell SN, Bruna A, Saadi A, Menon S, Hadfield J, Pugh M, Raj GV, Brown GD, ... ... Carroll JS, et al. Progesterone receptor modulates ERα action in breast cancer Nature. 523: 313-317. DOI: 10.1038/nature14583  0.379
2015 D'Santos C, Taylor C, Carroll JS, Mohammed H. RIME proteomics of estrogen and progesterone receptors in breast cancer Data in Brief. 5: 276-280. DOI: 10.1016/j.dib.2015.08.019  0.396
2014 Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, ... ... Carroll J, et al. Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications. 4: 4999. PMID 25248036 DOI: 10.1038/Ncomms5999  0.648
2014 Rosell M, Nevedomskaya E, Stelloo S, Nautiyal J, Poliandri A, Steel JH, Wessels LF, Carroll JS, Parker MG, Zwart W. Complex formation and function of estrogen receptor α in transcription requires RIP140. Cancer Research. 74: 5469-79. PMID 25145671 DOI: 10.1158/0008-5472.CAN-13-3429  0.494
2014 Rudraraju B, Droog M, Abdel-Fatah TM, Zwart W, Giannoudis A, Malki MI, Moore D, Patel H, Shaw J, Ellis IO, Chan S, Brooke GN, Nevedomskaya E, Lo Nigro C, Carroll J, et al. Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer. Breast Cancer Research and Treatment. 147: 295-309. PMID 25141981 DOI: 10.1007/S10549-014-3098-0  0.466
2014 Owens TW, Rogers RL, Best SA, Ledger A, Mooney AM, Ferguson A, Shore P, Swarbrick A, Ormandy CJ, Simpson PT, Carroll JS, Visvader JE, Naylor MJ. Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer. Cancer Research. 74: 5277-86. PMID 25056120 DOI: 10.1158/0008-5472.CAN-14-0053  0.422
2014 Ji Z, Mohammed H, Webber A, Ridsdale J, Han N, Carroll JS, Sharrocks AD. The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex. Nucleic Acids Research. 42: 6232-42. PMID 24748658 DOI: 10.1093/Nar/Gku274  0.302
2014 Robinson JL, Hickey TE, Warren AY, Vowler SL, Carroll T, Lamb AD, Papoutsoglou N, Neal DE, Tilley WD, Carroll JS. Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype. Oncogene. 33: 5666-74. PMID 24292680 DOI: 10.1038/onc.2013.508  0.313
2014 Carroll JS. Steroids, nuclear receptors and breast cancer. Preface. Molecular and Cellular Endocrinology. 382: 623. PMID 24125839 DOI: 10.1016/j.mce.2013.10.004  0.391
2014 Redmond A, Carroll J. 410: HER2 binds to the genome at specific regulatory sites of key genes in breast cancer European Journal of Cancer. 50: S98. DOI: 10.1016/S0959-8049(14)50365-6  0.408
2014 Carroll J. 375: Understanding estrogen receptor transcription in breast cancer European Journal of Cancer. 50: S89. DOI: 10.1016/s0959-8049(14)50334-6  0.445
2013 Lai CF, Flach KD, Alexi X, Fox SP, Ottaviani S, Thiruchelvam PT, Kyle FJ, Thomas RS, Launchbury R, Hua H, Callaghan HB, Carroll JS, Charles Coombes R, Zwart W, Buluwela L, et al. Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells. Nucleic Acids Research. 41: 10228-40. PMID 24049078 DOI: 10.1093/nar/gkt827  0.479
2013 Bhat-Nakshatri P, Song EK, Collins NR, Uversky VN, Dunker AK, O'Malley BW, Geistlinger TR, Carroll JS, Brown M, Nakshatri H. Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing. Bmc Medical Genomics. 6: 21. PMID 23758675 DOI: 10.1186/1755-8794-6-21  0.495
2013 Zwart W, Koornstra R, Wesseling J, Rutgers E, Linn S, Carroll JS. A carrier-assisted ChIP-seq method for estrogen receptor-chromatin interactions from breast cancer core needle biopsy samples. Bmc Genomics. 14: 232. PMID 23565824 DOI: 10.1186/1471-2164-14-232  0.466
2013 Robinson JL, Holmes KA, Carroll JS. FOXA1 mutations in hormone-dependent cancers. Frontiers in Oncology. 3: 20. PMID 23420418 DOI: 10.3389/fonc.2013.00020  0.433
2013 Mohammed H, D'Santos C, Serandour AA, Ali HR, Brown GD, Atkins A, Rueda OM, Holmes KA, Theodorou V, Robinson JL, Zwart W, Saadi A, Ross-Innes CS, Chin SF, Menon S, ... ... Carroll JS, et al. Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor. Cell Reports. 3: 342-9. PMID 23403292 DOI: 10.1016/j.celrep.2013.01.010  0.447
2013 Sanders DA, Ross-Innes CS, Beraldi D, Carroll JS, Balasubramanian S. Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells. Genome Biology. 14: R6. PMID 23347430 DOI: 10.1186/Gb-2013-14-1-R6  0.516
2013 Theodorou V, Stark R, Menon S, Carroll JS. GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility. Genome Research. 23: 12-22. PMID 23172872 DOI: 10.1101/gr.139469.112  0.498
2013 Carroll JS. Understanding estrogen receptor transcription in breast cancer Clinical Epigenetics. 5. DOI: 10.1186/1868-7083-5-S1-S7  0.445
2013 Carroll J. Abstract P4-04-01: Understanding estrogen receptor transcription in breast cancer Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P4-04-01  0.578
2013 Carroll J. Abstract AL-1: AACR outstanding investigator award for breast cancer research: Understanding estrogen receptor transcription in breast cancer Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-Al-1  0.571
2012 Kalyuga M, Gallego-Ortega D, Lee HJ, Roden DL, Cowley MJ, Caldon CE, Stone A, Allerdice SL, Valdes-Mora F, Launchbury R, Statham AL, Armstrong N, Alles MC, Young A, Egger A, ... ... Carroll JS, et al. ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. Plos Biology. 10: e1001461. PMID 23300383 DOI: 10.1371/journal.pbio.1001461  0.495
2012 Magnani L, Carroll J, Zwart W, Palmieri C. ChIPing away at breast cancer. The Lancet. Oncology. 13: 1185-7. PMID 23182190 DOI: 10.1016/S1470-2045(12)70511-9  0.456
2012 Meyer KB, Carroll JS. FOXA1 and breast cancer risk. Nature Genetics. 44: 1176-7. PMID 23104063 DOI: 10.1038/ng.2449  0.331
2012 Hickey TE, Robinson JL, Carroll JS, Tilley WD. Minireview: The androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene? Molecular Endocrinology (Baltimore, Md.). 26: 1252-67. PMID 22745190 DOI: 10.1210/me.2012-1107  0.431
2012 Robinson JL, Carroll JS. FoxA1 is a key mediator of hormonal response in breast and prostate cancer. Frontiers in Endocrinology. 3: 68. PMID 22649425 DOI: 10.3389/fendo.2012.00068  0.441
2012 Jozwik KM, Carroll JS. Pioneer factors in hormone-dependent cancers. Nature Reviews. Cancer. 12: 381-5. PMID 22555282 DOI: 10.1038/nrc3263  0.39
2012 Natrajan R, Mackay A, Lambros MB, Weigelt B, Wilkerson PM, Manie E, Grigoriadis A, A'hern R, van der Groep P, Kozarewa I, Popova T, Mariani O, Turajlic S, Furney SJ, Marais R, ... ... Carroll J, et al. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers. The Journal of Pathology. 227: 29-41. PMID 22362584 DOI: 10.1002/Path.4003  0.478
2012 Ross-Innes CS, Stark R, Teschendorff AE, Holmes KA, Ali HR, Dunning MJ, Brown GD, Gojis O, Ellis IO, Green AR, Ali S, Chin SF, Palmieri C, Caldas C, Carroll JS. Differential oestrogen receptor binding is associated with clinical outcome in breast cancer. Nature. 481: 389-93. PMID 22217937 DOI: 10.1038/nature10730  0.428
2012 Krijgsman O, Roepman P, Zwart W, Carroll JS, Tian S, de Snoo FA, Bender RA, Bernards R, Glas AM. A diagnostic gene profile for molecular subtyping of breast cancer associated with treatment response. Breast Cancer Research and Treatment. 133: 37-47. PMID 21814749 DOI: 10.1007/s10549-011-1683-z  0.388
2012 Holmes KA, Hurtado A, Brown GD, Launchbury R, Ross-Innes CS, Hadfield J, Odom DT, Carroll JS. Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 2748-53. PMID 21536917 DOI: 10.1073/Pnas.1018863108  0.416
2012 Carroll J. Abstract PL-2: Estrogen Receptor Cistrome: Implications for Breast Cancer Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-Pl-2  0.564
2012 Robinson JLL, MacArthur S, Ross-Innes CS, Tilley WD, Neal DE, Mills IG, Carroll JS. Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1 The Embo Journal. 31: 1617-1617. DOI: 10.1038/emboj.2012.59  0.434
2011 Zwart W, De Snoo F, Krijgsman O, Roepman P, Tian S, Glas A, Bender RA, Carroll J, Bernards R. Use of a gene profile to identify molecular subtypes of breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 537. PMID 28021484 DOI: 10.1200/Jco.2011.29.15_Suppl.537  0.545
2011 Ross-Innes CS, Brown GD, Carroll JS. A co-ordinated interaction between CTCF and ER in breast cancer cells. Bmc Genomics. 12: 593. PMID 22142239 DOI: 10.1186/1471-2164-12-593  0.449
2011 Zaret KS, Carroll JS. Pioneer transcription factors: establishing competence for gene expression. Genes & Development. 25: 2227-41. PMID 22056668 DOI: 10.1101/Gad.176826.111  0.307
2011 Zwart W, Theodorou V, Kok M, Canisius S, Linn S, Carroll JS. Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer. The Embo Journal. 30: 4764-76. PMID 22002538 DOI: 10.1038/emboj.2011.368  0.455
2011 Meyer KB, Maia AT, O'Reilly M, Ghoussaini M, Prathalingam R, Porter-Gill P, Ambs S, Prokunina-Olsson L, Carroll J, Ponder BAJ. A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression Plos Genetics. 7. PMID 21814516 DOI: 10.1371/Journal.Pgen.1002165  0.42
2011 Robinson JL, Macarthur S, Ross-Innes CS, Tilley WD, Neal DE, Mills IG, Carroll JS. Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1. The Embo Journal. 30: 3019-27. PMID 21701558 DOI: 10.1038/emboj.2011.216  0.486
2011 Holland DG, Burleigh A, Git A, Goldgraben MA, Perez-Mancera PA, Chin SF, Hurtado A, Bruna A, Ali HR, Greenwood W, Dunning MJ, Samarajiwa S, Menon S, Rueda OM, Lynch AG, ... ... Carroll JS, et al. ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium. Embo Molecular Medicine. 3: 167-80. PMID 21337521 DOI: 10.1002/Emmm.201100122  0.429
2011 Zwart W, Theodorou V, Carroll JS. Estrogen receptor-positive breast cancer: a multidisciplinary challenge. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 216-30. PMID 21305704 DOI: 10.1002/wsbm.109  0.431
2011 Hurtado A, Holmes KA, Ross-Innes CS, Schmidt D, Carroll JS. FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nature Genetics. 43: 27-33. PMID 21151129 DOI: 10.1038/ng.730  0.487
2011 Thiruchelvam PT, Lai CF, Hua H, Thomas RS, Hurtado A, Hudson W, Bayly AR, Kyle FJ, Periyasamy M, Photiou A, Spivey AC, Ortlund EA, Whitby RJ, Carroll JS, Coombes RC, et al. The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells. Breast Cancer Research and Treatment. 127: 385-96. PMID 20607599 DOI: 10.1007/S10549-010-0994-9  0.518
2011 Zwart W, Theodorou V, Kok M, Canisius S, Linn S, Carroll JS. Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer The Embo Journal. 30: 4850-4850. DOI: 10.1038/emboj.2011.414  0.455
2010 Lupien M, Meyer CA, Bailey ST, Eeckhoute J, Cook J, Westerling T, Zhang X, Carroll JS, Rhodes DR, Liu XS, Brown M. Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance. Genes & Development. 24: 2219-27. PMID 20889718 DOI: 10.1101/Gad.1944810  0.726
2010 Badve S, Collins NR, Bhat-Nakshatri P, Turbin D, Leung S, Thorat M, Dunn SE, Geistlinger TR, Carroll JS, Brown M, Bose S, Teitell MA, Nakshatri H. Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications. The American Journal of Pathology. 176: 2139-49. PMID 20228224 DOI: 10.2353/Ajpath.2010.090477  0.609
2010 Schmidt D, Schwalie PC, Ross-Innes CS, Hurtado A, Brown GD, Carroll JS, Flicek P, Odom DT. A CTCF-independent role for cohesin in tissue-specific transcription. Genome Research. 20: 578-88. PMID 20219941 DOI: 10.1101/Gr.100479.109  0.465
2010 Theodorou V, Carroll JS. Estrogen receptor action in three dimensions - looping the loop. Breast Cancer Research : Bcr. 12: 303. PMID 20156333 DOI: 10.1186/bcr2470  0.391
2010 Ross-Innes CS, Stark R, Holmes KA, Schmidt D, Spyrou C, Russell R, Massie CE, Vowler SL, Eldridge M, Carroll JS. Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer. Genes & Development. 24: 171-82. PMID 20080953 DOI: 10.1101/gad.552910  0.358
2009 Redmond AM, Carroll JS. Defining and targeting transcription factors in cancer. Genome Biology. 10: 311. PMID 19664186 DOI: 10.1186/gb-2009-10-7-311  0.323
2009 Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Lupien M, Wu T, Regan MM, Meyer CA, Carroll JS, Manrai AK, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell. 138: 245-56. PMID 19632176 DOI: 10.1016/J.Cell.2009.04.056  0.679
2009 Bhat-Nakshatri P, Wang G, Collins NR, Thomson MJ, Geistlinger TR, Carroll JS, Brown M, Hammond S, Srour EF, Liu Y, Nakshatri H. Estradiol-regulated microRNAs control estradiol response in breast cancer cells. Nucleic Acids Research. 37: 4850-61. PMID 19528081 DOI: 10.1093/Nar/Gkp500  0.555
2009 Nucera C, Eeckhoute J, Finn S, Carroll JS, Ligon AH, Priolo C, Fadda G, Toner M, Sheils O, Attard M, Pontecorvi A, Nose V, Loda M, Brown M. FOXA1 is a potential oncogene in anaplastic thyroid carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3680-9. PMID 19470727 DOI: 10.1158/1078-0432.Ccr-08-3155  0.419
2009 Xia X, Lemieux ME, Li W, Carroll JS, Brown M, Liu XS, Kung AL. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 106: 4260-5. PMID 19255431 DOI: 10.1073/Pnas.0810067106  0.479
2009 Hurtado A, Holmes KA, Geistlinger TR, Hutcheson IR, Nicholson RI, Brown M, Jiang J, Howat WJ, Ali S, Carroll JS. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen (Nature (2008) 456, (663-666)) Nature. 457: 1168. DOI: 10.1038/Nature07835  0.404
2008 Hurtado A, Holmes KA, Geistlinger TR, Hutcheson IR, Nicholson RI, Brown M, Jiang J, Howat WJ, Ali S, Carroll JS. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature. 456: 663-6. PMID 19005469 DOI: 10.1038/Nature07483  0.656
2008 Bhat-Nakshatri P, Wang G, Appaiah H, Luktuke N, Carroll JS, Geistlinger TR, Brown M, Badve S, Liu Y, Nakshatri H. AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer. Molecular and Cellular Biology. 28: 7487-503. PMID 18838536 DOI: 10.1128/Mcb.00799-08  0.633
2008 Krum SA, Miranda-Carboni GA, Lupien M, Eeckhoute J, Carroll JS, Brown M. Unique ERalpha cistromes control cell type-specific gene regulation. Molecular Endocrinology (Baltimore, Md.). 22: 2393-406. PMID 18818283 DOI: 10.1210/Me.2008-0100  0.691
2008 Holmes KA, Song JS, Liu XS, Brown M, Carroll JS. Nkx3-1 and LEF-1 function as transcriptional inhibitors of estrogen receptor activity. Cancer Research. 68: 7380-5. PMID 18794125 DOI: 10.1158/0008-5472.Can-08-0133  0.609
2008 Dietz SC, Carroll JS. Interrogating the genome to understand oestrogen-receptor-mediated transcription. Expert Reviews in Molecular Medicine. 10: e10. PMID 18377699 DOI: 10.1017/S1462399408000653  0.471
2008 Li W, Carroll JS, Brown M, Liu xS. xMAN: extreme MApping of OligoNucleotides. Bmc Genomics. 9: S20. PMID 18366610 DOI: 10.1186/1471-2164-9-S1-S20  0.381
2008 Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, Carroll JS, Liu XS, Brown M. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell. 132: 958-70. PMID 18358809 DOI: 10.1016/J.Cell.2008.01.018  0.649
2008 Johnson DS, Li W, Gordon DB, Bhattacharjee A, Curry B, Ghosh J, Brizuela L, Carroll JS, Brown M, Flicek P, Koch CM, Dunham I, Bieda M, Xu X, Farnham PJ, et al. Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Research. 18: 393-403. PMID 18258921 DOI: 10.1101/Gr.7080508  0.4
2008 Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP, Brown M. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. The Embo Journal. 27: 535-45. PMID 18219273 DOI: 10.1038/Sj.Emboj.7601984  0.457
2007 Green KA, Carroll JS. Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state. Nature Reviews. Cancer. 7: 713-22. PMID 17721435 DOI: 10.1038/nrc2211  0.45
2007 Wang Q, Li W, Liu XS, Carroll JS, Jänne OA, Keeton EK, Chinnaiyan AM, Pienta KJ, Brown M. A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Molecular Cell. 27: 380-92. PMID 17679089 DOI: 10.1016/J.Molcel.2007.05.041  0.545
2007 Eeckhoute J, Keeton EK, Lupien M, Krum SA, Carroll JS, Brown M. Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Research. 67: 6477-83. PMID 17616709 DOI: 10.1158/0008-5472.Can-07-0746  0.709
2006 Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, et al. Genome-wide analysis of estrogen receptor binding sites. Nature Genetics. 38: 1289-97. PMID 17013392 DOI: 10.1038/Ng1901  0.645
2006 Eeckhoute J, Carroll JS, Geistlinger TR, Torres-Arzayus MI, Brown M. A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. Genes & Development. 20: 2513-26. PMID 16980581 DOI: 10.1101/Gad.1446006  0.657
2006 Johnson WE, Li W, Meyer CA, Gottardo R, Carroll JS, Brown M, Liu XS. Model-based analysis of tiling-arrays for ChIP-chip. Proceedings of the National Academy of Sciences of the United States of America. 103: 12457-62. PMID 16895995 DOI: 10.1073/Pnas.0601180103  0.398
2006 Carroll DK, Carroll JS, Leong CO, Cheng F, Brown M, Mills AA, Brugge JS, Ellisen LW. p63 regulates an adhesion programme and cell survival in epithelial cells. Nature Cell Biology. 8: 551-61. PMID 16715076 DOI: 10.1038/Ncb1420  0.466
2006 Carroll JS, Brown M. Estrogen receptor target gene: an evolving concept. Molecular Endocrinology (Baltimore, Md.). 20: 1707-14. PMID 16396959 DOI: 10.1210/Me.2005-0334  0.595
2005 Wang Q, Carroll JS, Brown M. Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking. Molecular Cell. 19: 631-42. PMID 16137620 DOI: 10.1016/J.Molcel.2005.07.018  0.512
2005 Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell. 122: 33-43. PMID 16009131 DOI: 10.1016/J.Cell.2005.05.008  0.769
2003 Carroll JS, Lynch DK, Swarbrick A, Renoir JM, Sarcevic B, Daly RJ, Musgrove EA, Sutherland RL. p27(Kip1) induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells. Cancer Research. 63: 4322-6. PMID 12907598  0.348
2003 Doisneau-Sixou SF, Sergio CM, Carroll JS, Hui R, Musgrove EA, Sutherland RL. Estrogen and antiestrogen regulation of cell cycle progression in breast cancer cells. Endocrine-Related Cancer. 10: 179-86. PMID 12790780 DOI: 10.1677/ERC.0.0100179  0.349
2003 Doisneau-Sixou SF, Cestac P, Chouini S, Carroll JS, Hamilton AD, Sebti SM, Poirot M, Balaguer P, Faye JC, Sutherland RL, Favre G. Contrasting effects of prenyltransferase inhibitors on estrogen-dependent cell cycle progression and estrogen receptor-mediated transcriptional activity in MCF-7 cells. Endocrinology. 144: 989-98. PMID 12586776 DOI: 10.1210/En.2002-220726  0.359
2003 Sutherland RL, Carroll JS, Sergio CM, Swarbrick A, Musgrove EA. 97. Steroid regulation of breast cancer cell proliferation Reproduction, Fertility and Development. 15: 97. DOI: 10.1071/SRB03Ab97  0.426
2002 Carroll JS, Swarbrick A, Musgrove EA, Sutherland RL. Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens. Cancer Research. 62: 3126-31. PMID 12036924  0.359
Show low-probability matches.