Shankar Balasubramanian, Ph.D. - Publications

1994- Chemistry University of Cambridge, Cambridge, England, United Kingdom 
DNA, quadruplexes, sequencing

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Year Citation  Score
2020 Varshney D, Spiegel J, Zyner K, Tannahill D, Balasubramanian S. The regulation and functions of DNA and RNA G-quadruplexes. Nature Reviews. Molecular Cell Biology. PMID 32313204 DOI: 10.1038/s41580-020-0236-x  1
2020 Liu KC, Röder K, Mayer C, Adhikari S, Wales DJ, Balasubramanian S. Affinity-selected bicyclic peptide G-quadruplex ligands mimic a protein-like binding mechanism. Journal of the American Chemical Society. PMID 32267689 DOI: 10.1021/jacs.0c01879  0.8
2019 Weber J, Bollepalli L, Belenguer AM, Di Antonio M, De Mitri N, Joseph J, Balasubramanian S, Hunter CA, Bohndiek SE. An activatable cancer-targeted hydrogen peroxide probe for photoacoustic and fluorescence imaging. Cancer Research. PMID 31455691 DOI: 10.1158/0008-5472.CAN-19-0691  0.84
2019 Sahakyan A, Mahtey A, Kawasaki F, Balasubramanian S. A Spontaneous Ring Opening Reaction Leads to a Repair-Resistant T Oxidation Product in Genomic DNA. Chembiochem : a European Journal of Chemical Biology. PMID 31386787 DOI: 10.1002/cbic.201900484  0.76
2019 Zyner KG, Mulhearn DS, Adhikari S, Martínez Cuesta S, Di Antonio M, Erard N, Hannon GJ, Tannahill D, Balasubramanian S. Genetic interactions of G-quadruplexes in humans. Elife. 8. PMID 31287417 DOI: 10.7554/eLife.46793  1
2019 Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 20: 124. PMID 31215477 DOI: 10.1186/s13059-019-1737-9  1
2019 Liu ZJ, Martínez Cuesta S, van Delft P, Balasubramanian S. Sequencing abasic sites in DNA at single-nucleotide resolution. Nature Chemistry. 11: 629-637. PMID 31209299 DOI: 10.1038/s41557-019-0279-9  0.64
2019 Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d'Onofrio M, Balasubramanian S, Kouzarides T. METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Molecular Cell. PMID 31031083 DOI: 10.1016/j.molcel.2019.03.040  0.8
2019 Marsico G, Chambers VS, Sahakyan AB, McCauley P, Boutell JM, Di Antonio M, Balasubramanian S. Whole genome experimental maps of DNA G-quadruplexes in multiple species. Nucleic Acids Research. PMID 30892612 DOI: 10.1093/nar/gkz179  1
2019 Nguyen HP, Stewart S, Kukwikila MN, Jones SF, Offenbartl-Stiegert D, Mao S, Balasubramanian S, Beck S, Howorka S. Opto-epigenetic modulation of DNA methylation with a photo-responsive small-molecule approach. Angewandte Chemie (International Ed. in English). PMID 30773767 DOI: 10.1002/anie.201901139  0.4
2019 Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 20: 11. PMID 30635026 DOI: 10.1186/s13059-019-1623-5  1
2018 Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 19: 229. PMID 30591072 DOI: 10.1186/s13059-018-1602-2  1
2018 Sengar A, Vandana JJ, Chambers VS, Di Antonio M, Winnerdy FR, Balasubramanian S, Phan AT. Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter. Nucleic Acids Research. PMID 30551210 DOI: 10.1093/nar/gky1179  0.84
2018 Raiber EA, Portella G, Martínez Cuesta S, Hardisty R, Murat P, Li Z, Iurlaro M, Dean W, Spindel J, Beraldi D, Liu Z, Dawson MA, Reik W, Balasubramanian S. 5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells. Nature Chemistry. PMID 30349137 DOI: 10.1038/s41557-018-0149-x  0.96
2018 Mao SQ, Ghanbarian AT, Spiegel J, Martínez Cuesta S, Beraldi D, Di Antonio M, Marsico G, Hänsel-Hertsch R, Tannahill D, Balasubramanian S. DNA G-quadruplex structures mold the DNA methylome. Nature Structural & Molecular Biology. PMID 30275516 DOI: 10.1038/s41594-018-0131-8  1
2018 Herdy B, Mayer C, Varshney D, Marsico G, Murat P, Taylor C, D'Santos C, Tannahill D, Balasubramanian S. Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts. Nucleic Acids Research. PMID 30256975 DOI: 10.1093/nar/gky861  1
2018 Kwok CK, Marsico G, Balasubramanian S. Detecting RNA G-Quadruplexes (rG4s) in the Transcriptome. Cold Spring Harbor Perspectives in Biology. 10. PMID 29967010 DOI: 10.1101/cshperspect.a032284  1
2018 Chen MC, Tippana R, Demeshkina NA, Murat P, Balasubramanian S, Myong S, Ferré-D'Amaré AR. Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature. PMID 29899445 DOI: 10.1038/s41586-018-0209-9  0.8
2018 Kawasaki F, Martínez Cuesta S, Beraldi D, Mahtey A, Hardisty RE, Carrington M, Balasubramanian S. Sequencing 5-hydroxymethyluracil at single-base resolution. Angewandte Chemie (International Ed. in English). PMID 29882366 DOI: 10.1002/anie.201804046  0.76
2018 Parry AJ, Hoare M, Bihary D, Hänsel-Hertsch R, Smith S, Tomimatsu K, Mannion E, Smith A, D'Santos P, Russell IA, Balasubramanian S, Kimura H, Samarajiwa SA, Narita M. NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence. Nature Communications. 9: 1840. PMID 29743479 DOI: 10.1038/s41467-018-04283-9  0.96
2018 Hänsel-Hertsch R, Spiegel J, Marsico G, Tannahill D, Balasubramanian S. Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing. Nature Protocols. 13: 551-564. PMID 29470465 DOI: 10.1038/nprot.2017.150  1
2018 Marchetti C, Zyner KG, Ohnmacht SA, Robson M, Haider SM, Morton JP, Marsico G, Vo T, Laughlin-Toth S, Ahmed AA, Di Vita G, Pazitna I, Gunaratnam M, Besser RJ, Andrade AC, ... ... Balasubramanian S, et al. Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule. Journal of Medicinal Chemistry. PMID 29356532 DOI: 10.1021/acs.jmedchem.7b01781  1
2017 Raiber EA, Beraldi D, Martínez Cuesta S, McInroy GR, Kingsbury Z, Becq J, James T, Lopes M, Allinson K, Field S, Humphray S, Santarius T, Watts C, Bentley D, Balasubramanian S. Base resolution maps reveal the importance of 5-hydroxymethylcytosine in a human glioblastoma. Npj Genomic Medicine. 2: 6. PMID 29263824 DOI: 10.1038/s41525-017-0007-6  0.96
2017 Sahakyan AB, Chambers VS, Marsico G, Santner T, Di Antonio M, Balasubramanian S. Machine learning model for sequence-driven DNA G-quadruplex formation. Scientific Reports. 7: 14535. PMID 29109402 DOI: 10.1038/s41598-017-14017-4  1
2017 Guilbaud G, Murat P, Recolin B, Campbell BC, Maiter A, Sale JE, Balasubramanian S. Local epigenetic reprogramming induced by G-quadruplex ligands. Nature Chemistry. 9: 1110-1117. PMID 29064488 DOI: 10.1038/nchem.2828  0.8
2017 van Delft P, Akay A, Huber SM, Bueschl C, Rudolph KLM, Di Domenico T, Schuhmacher R, Miska EA, Balasubramanian S. The Profile and Dynamics of RNA Modifications in Animals. Chembiochem : a European Journal of Chemical Biology. PMID 28449301 DOI: 10.1002/cbic.201700093  0.64
2017 Hänsel-Hertsch R, Antonio MD, Balasubramanian S. DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential. Nature Reviews. Molecular Cell Biology. PMID 28225080 DOI: 10.1038/nrm.2017.3  0.96
2017 Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, ... ... Balasubramanian S, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nature Communications. 8: 14432. PMID 28211448 DOI: 10.1038/ncomms14432  0.84
2017 Milagre I, Stubbs TM, King MR, Spindel J, Santos F, Krueger F, Bachman M, Segonds-Pichon A, Balasubramanian S, Andrews SR, Dean W, Reik W. Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming. Cell Reports. 18: 1079-1089. PMID 28147265 DOI: 10.1016/j.celrep.2017.01.008  0.6
2017 Kawasaki F, Beraldi D, Hardisty RE, McInroy GR, van Delft P, Balasubramanian S. Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania. Genome Biology. 18: 23. PMID 28137275 DOI: 10.1186/s13059-017-1150-1  0.92
2017 Sahakyan AB, Murat P, Mayer C, Balasubramanian S. G-quadruplex structures within the 3' UTR of LINE-1 elements stimulate retrotransposition. Nature Structural & Molecular Biology. PMID 28134931 DOI: 10.1038/nsmb.3367  1
2017 Huber SM, van Delft P, Tanpure AA, Miska EA, Balasubramanian S. 2'-O-methyl-5-hydroxymethylcytidine - a second oxidative derivative of 5-methylcytidine in RNA. Journal of the American Chemical Society. PMID 28107630 DOI: 10.1021/jacs.6b12180  0.64
2017 Sahakyan AB, Balasubramanian S. Single genome retrieval of context-dependent variability in mutation rates for human germline. Bmc Genomics. 18: 81. PMID 28086752 DOI: 10.1186/s12864-016-3440-5  1
2016 Hore TA, von Meyenn F, Ravichandran M, Bachman M, Ficz G, Oxley D, Santos F, Balasubramanian S, Jurkowski TP, Reik W. Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms. Proceedings of the National Academy of Sciences of the United States of America. PMID 27729528 DOI: 10.1073/pnas.1608679113  0.6
2016 Hänsel-Hertsch R, Beraldi D, Lensing SV, Marsico G, Zyner K, Parry A, Di Antonio M, Pike J, Kimura H, Narita M, Tannahill D, Balasubramanian S. G-quadruplex structures mark human regulatory chromatin. Nature Genetics. PMID 27618450 DOI: 10.1038/ng.3662  1
2016 Kwok CK, Marsico G, Sahakyan AB, Chambers VS, Balasubramanian S. rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome. Nature Methods. PMID 27571552 DOI: 10.1038/nmeth.3965  1
2016 Lensing SV, Marsico G, Hänsel-Hertsch R, Lam EY, Tannahill D, Balasubramanian S. DSBCapture: in situ capture and sequencing of DNA breaks. Nature Methods. PMID 27525976 DOI: 10.1038/nmeth.3960  1
2016 Mayer C, McInroy GR, Murat P, Van Delft P, Balasubramanian S. An Epigenetics-Inspired DNA-Based Data Storage System. Angewandte Chemie (International Ed. in English). PMID 27440712 DOI: 10.1002/anie.201605531  1
2016 Iurlaro M, McInroy GR, Burgess HE, Dean W, Raiber EA, Bachman M, Beraldi D, Balasubramanian S, Reik W. In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine. Genome Biology. 17: 141. PMID 27356509 DOI: 10.1186/s13059-016-1001-5  1
2016 Kwok CK, Sahakyan AB, Balasubramanian S. Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA. Angewandte Chemie (International Ed. in English). PMID 27355429 DOI: 10.1002/anie.201603562  1
2016 McInroy GR, Beraldi D, Raiber EA, Modrzynska K, van Delft P, Billker O, Balasubramanian S. Enhanced Methylation Analysis by Recovery of Unsequenceable Fragments. Plos One. 11: e0152322. PMID 27031619 DOI: 10.1371/journal.pone.0152322  1
2016 Sahakyan AB, Balasubramanian S. Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases. Bmc Genomics. 17: 225. PMID 26968808 DOI: 10.1186/s12864-016-2582-9  1
2016 Xie Y, Bowe B, Xian H, Balasubramanian S, Al-Aly Z. Estimated GFR Trajectories of People Entering CKD Stage 4 and Subsequent Kidney Disease Outcomes and Mortality. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 26948835 DOI: 10.1053/j.ajkd.2016.02.039  0.32
2016 Malouf GG, Ali SM, Wang K, Balasubramanian S, Ross JS, Miller VA, Stephens PJ, Khayat D, Pal SK, Su X, Sircar K, Tamboli P, Jonasch E, Tannir NM, Wood CG, et al. Genomic Characterization of Renal Cell Carcinoma with Sarcomatoid Dedifferentiation Pinpoints Recurrent Genomic Alterations. European Urology. PMID 26895810 DOI: 10.1016/j.eururo.2016.01.051  0.32
2016 Cording A, Gormally M, Bond PJ, Carrington M, Balasubramanian S, Miska EA, Thomas B. Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications. Rna Biology. 0. PMID 26786754 DOI: 10.1080/15476286.2015.1137422  1
2016 Walker OS, Elsässer SJ, Mahesh M, Bachman M, Balasubramanian S, Chin JW. Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes. Journal of the American Chemical Society. PMID 26761588 DOI: 10.1021/jacs.5b07627  1
2015 Patalano S, Vlasova A, Wyatt C, Ewels P, Camara F, Ferreira PG, Asher CL, Jurkowski TP, Segonds-Pichon A, Bachman M, González-Navarrete I, Minoche AE, Krueger F, Lowy E, Marcet-Houben M, ... ... Balasubramanian S, et al. Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies. Proceedings of the National Academy of Sciences of the United States of America. 112: 13970-5. PMID 26483466 DOI: 10.1073/pnas.1515937112  1
2015 Ozluk Y, Taheri D, Matoso A, Sanli O, Berker NK, Yakirevich E, Balasubramanian S, Ross JS, Ali SM, Netto GJ. Renal carcinoma associated with a novel succinate dehydrogenase A mutation: a case report and review of literature of a rare subtype of renal carcinoma. Human Pathology. PMID 26476567 DOI: 10.1016/j.humpath.2015.07.027  0.32
2015 Li YR, van Setten J, Verma SS, Lu Y, Holmes MV, Gao H, Lek M, Nair N, Chandrupatla H, Chang B, Karczewski KJ, Wong C, Mohebnasab M, Mukhtar E, Phillips R, ... ... Balasubramanian S, et al. Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies. Genome Medicine. 7: 90. PMID 26423053 DOI: 10.1186/s13073-015-0211-x  0.4
2015 Chumsri S, Weidler J, Ali S, Balasubramanian S, Wallweber G, DeFazio-Eli L, Chenna A, Huang W, DeRidder A, Goicocheal L, Perez EA. Prolonged Response to Trastuzumab in a Patient With HER2-Nonamplified Breast Cancer With Elevated HER2 Dimerization Harboring an ERBB2 S310F Mutation. Journal of the National Comprehensive Cancer Network : Jnccn. 13: 1066-70. PMID 26358791  0.32
2015 Xie Y, Bowe B, Xian H, Balasubramanian S, Al-Aly Z. Rate of Kidney Function Decline and Risk of Hospitalizations in Stage 3A CKD. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 26350437 DOI: 10.2215/CJN.04480415  0.32
2015 Yangyuoru PM, Di Antonio M, Ghimire C, Biffi G, Balasubramanian S, Mao H. Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 127: 924-927. PMID 26300569 DOI: 10.1002/ange.201408113  1
2015 Chambers VS, Marsico G, Boutell JM, Di Antonio M, Smith GP, Balasubramanian S. High-throughput sequencing of DNA G-quadruplex structures in the human genome. Nature Biotechnology. PMID 26192317 DOI: 10.1038/nbt.3295  1
2015 Lee J, Kim HC, Hong JY, Wang K, Kim SY, Jang J, Kim ST, Park JO, Lim HY, Kang WK, Park YS, Lee J, Lee WY, Park YA, Huh JW, ... ... Balasubramanian S, et al. Detection of novel and potentially actionable anaplastic lymphoma kinase (ALK) rearrangement in colorectal adenocarcinoma by immunohistochemistry screening. Oncotarget. PMID 26172300 DOI: 10.18632/oncotarget.4462  0.32
2015 Sanders DA, Gormally MV, Marsico G, Beraldi D, Tannahill D, Balasubramanian S. FOXM1 binds directly to non-consensus sequences in the human genome. Genome Biology. 16: 130. PMID 26100407 DOI: 10.1186/s13059-015-0696-z  1
2015 Bachman M, Uribe-Lewis S, Yang X, Burgess HE, Iurlaro M, Reik W, Murrell A, Balasubramanian S. 5-Formylcytosine can be a stable DNA modification in mammals. Nature Chemical Biology. PMID 26098680 DOI: 10.1038/nchembio.1848  1
2015 Le Rolle AF, Klempner SJ, Garrett CR, Seery T, Sanford EM, Balasubramanian S, Ross JS, Stephens PJ, Miller VA, Ali SM, Chiu VK. Identification and characterization of RET fusions in advanced colorectal cancer. Oncotarget. PMID 26078337 DOI: 10.18632/oncotarget.4325  0.32
2015 Adhikary G, Grun D, Balasubramanian S, Kerr C, Huang JM, Eckert RL. Survival of skin cancer stem cells requires the Ezh2 polycomb group protein. Carcinogenesis. 36: 800-10. PMID 25969142 DOI: 10.1093/carcin/bgv064  0.36
2015 Hardisty RE, Kawasaki F, Sahakyan AB, Balasubramanian S. Selective Chemical Labeling of Natural T Modifications in DNA. Journal of the American Chemical Society. PMID 25946119 DOI: 10.1021/jacs.5b03730  1
2015 Kwok CK, Balasubramanian S. Targeted Detection of G-Quadruplexes in Cellular RNAs. Angewandte Chemie (International Ed. in English). 54: 6751-4. PMID 25907625 DOI: 10.1002/anie.201500891  1
2015 Levin MK, Wang K, Yelensky R, Cao Y, Ramos C, Hoke N, Pippen J, Blum JL, Brooks B, Palmer G, Palma N, Balasubramanian S, Ross JS, O'Shaughnessy J. Genomic alterations in DNA repair and chromatin remodeling genes in estrogen receptor-positive metastatic breast cancer patients with exceptional responses to capecitabine. Cancer Medicine. PMID 25871911 DOI: 10.1002/cam4.464  0.32
2015 Le DD, Di Antonio M, Chan LK, Balasubramanian S. G-quadruplex ligands exhibit differential G-tetrad selectivity. Chemical Communications (Cambridge, England). 51: 8048-50. PMID 25864836 DOI: 10.1039/c5cc02252e  1
2015 Balasubramanian S, Scharadin TM, Han B, Xu W, Eckert RL. The Bmi-1 helix-turn and ring finger domains are required for Bmi-1 antagonism of (-) epigallocatechin-3-gallate suppression of skin cancer cell survival. Cellular Signalling. 27: 1336-44. PMID 25843776 DOI: 10.1016/j.cellsig.2015.03.021  0.36
2015 Field SF, Beraldi D, Bachman M, Stewart SK, Beck S, Balasubramanian S. Accurate measurement of 5-methylcytosine and 5-hydroxymethylcytosine in human cerebellum DNA by oxidative bisulfite on an array (OxBS-array). Plos One. 10: e0118202. PMID 25706862 DOI: 10.1371/journal.pone.0118202  1
2015 Huber SM, van Delft P, Mendil L, Bachman M, Smollett K, Werner F, Miska EA, Balasubramanian S. Formation and abundance of 5-hydroxymethylcytosine in RNA. Chembiochem : a European Journal of Chemical Biology. 16: 752-5. PMID 25676849 DOI: 10.1002/cbic.201500013  1
2015 Chen MC, Murat P, Abecassis K, Ferré-D'Amaré AR, Balasubramanian S. Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase. Nucleic Acids Research. 43: 2223-31. PMID 25653156 DOI: 10.1093/nar/gkv051  1
2015 Balasubramanian S. Decoding genomes. Biochemical Society Transactions. 43: 1-5. PMID 25619239 DOI: 10.1042/BST20140254  1
2015 Pervouchine DD, Djebali S, Breschi A, Davis CA, Barja PP, Dobin A, Tanzer A, Lagarde J, Zaleski C, See LH, Fastuca M, Drenkow J, Wang H, Bussotti G, Pei B, ... Balasubramanian S, et al. Enhanced transcriptome maps from multiple mouse tissues reveal evolutionary constraint in gene expression. Nature Communications. 6: 5903. PMID 25582907 DOI: 10.1038/ncomms6903  0.4
2015 Drilon A, Wang L, Arcila ME, Balasubramanian S, Greenbowe JR, Ross JS, Stephens P, Lipson D, Miller VA, Kris MG, Ladanyi M, Rizvi NA. Broad, Hybrid Capture-Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25567908 DOI: 10.1158/1078-0432.CCR-14-2683  0.32
2015 Raiber EA, Murat P, Chirgadze DY, Beraldi D, Luisi BF, Balasubramanian S. 5-Formylcytosine alters the structure of the DNA double helix. Nature Structural & Molecular Biology. 22: 44-9. PMID 25504322 DOI: 10.1038/nsmb.2936  1
2015 Yangyuoru PM, Di Antonio M, Ghimire C, Biffi G, Balasubramanian S, Mao H. Dual binding of an antibody and a small molecule increases the stability of TERRA G-quadruplex. Angewandte Chemie (International Ed. in English). 54: 910-3. PMID 25421962 DOI: 10.1002/anie.201408113  1
2015 Balasubramanian S. Solexa sequencing: decoding genomes on a population scale. Clinical Chemistry. 61: 21-4. PMID 25332311 DOI: 10.1373/clinchem.2014.221747  1
2015 Stewart SK, Morris TJ, Guilhamon P, Bulstrode H, Bachman M, Balasubramanian S, Beck S. oxBS-450K: a method for analysing hydroxymethylation using 450K BeadChips. Methods (San Diego, Calif.). 72: 9-15. PMID 25175075 DOI: 10.1016/j.ymeth.2014.08.009  1
2015 Booth MJ, Raiber EA, Balasubramanian S. Chemical methods for decoding cytosine modifications in DNA. Chemical Reviews. 115: 2240-54. PMID 25094039 DOI: 10.1021/cr5002904  1
2015 Balasubramanian S, Bhattacharya S, Krishnan VV. Pricing information goods: A strategic analysis of the selling and pay-per-use mechanisms Marketing Science. 34: 218-234. DOI: 10.1287/mksc.2014.0894  0.52
2015 McInroy GR, Bell NM, Ficz G, Balasubramanian S, Reik W, Raiber EA. The biology and genomic localization of cytosine modifications Epigenetics and Human Health. 4: 167-191. DOI: 10.1007/978-3-642-31974-7_8  1
2015 Jones Christensen L, Siemsen E, Balasubramanian S. Consumer behavior change at the base of the pyramid: Bridging the gap between for-profit and social responsibility strategies Strategic Management Journal. 36: 307-317. DOI: 10.1002/smj.2249  0.52
2015 Balasubramanian S, Koloutsou-Vakakis S, Mcfarland DM, Rood MJ. Reconsidering emissions of ammonia from chemical fertilizer usage in Midwest USA Journal of Geophysical Research D: Atmospheres. DOI: 10.1002/2015JD023219  0.36
2015 Sainam P, Balasubramanian S, Bayus BL. Consumer forwards: Concept and empirical analysis of a sports ticket market International Journal of Sport Finance. 10: 103-121.  0.52
2014 Bachman M, Uribe-Lewis S, Yang X, Williams M, Murrell A, Balasubramanian S. 5-Hydroxymethylcytosine is a predominantly stable DNA modification. Nature Chemistry. 6: 1049-55. PMID 25411882 DOI: 10.1038/nchem.2064  1
2014 Gormally MV, Dexheimer TS, Marsico G, Sanders DA, Lowe C, Matak-Vinkovi? D, Michael S, Jadhav A, Rai G, Maloney DJ, Simeonov A, Balasubramanian S. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nature Communications. 5: 5165. PMID 25387393 DOI: 10.1038/ncomms6165  1
2014 Chmielecki J, Hutchinson KE, Frampton GM, Chalmers ZR, Johnson A, Shi C, Elvin J, Ali SM, Ross JS, Basturk O, Balasubramanian S, Lipson D, Yelensky R, Pao W, Miller VA, et al. Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes. Cancer Discovery. 4: 1398-405. PMID 25266736 DOI: 10.1158/2159-8290.CD-14-0617  0.32
2014 Müller S, Laxmi-Reddy K, Jena PV, Baptiste B, Dong Z, Godde F, Ha T, Rodriguez R, Balasubramanian S, Huc I. Targeting DNA G-quadruplexes with helical small molecules. Chembiochem : a European Journal of Chemical Biology. 15: 2563-70. PMID 25256604 DOI: 10.1002/cbic.201402439  1
2014 Schiavone D, Guilbaud G, Murat P, Papadopoulou C, Sarkies P, Prioleau MN, Balasubramanian S, Sale JE. Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells. The Embo Journal. 33: 2507-20. PMID 25190518 DOI: 10.15252/embj.201488398  1
2014 McInroy GR, Raiber EA, Balasubramanian S. Chemical biology of genomic DNA: minimizing PCR bias. Chemical Communications (Cambridge, England). 50: 12047-9. PMID 25178041 DOI: 10.1039/c4cc05107f  1
2014 Sisu C, Pei B, Leng J, Frankish A, Zhang Y, Balasubramanian S, Harte R, Wang D, Rutenberg-Schoenberg M, Clark W, Diekhans M, Rozowsky J, Hubbard T, Harrow J, Gerstein MB. Comparative analysis of pseudogenes across three phyla. Proceedings of the National Academy of Sciences of the United States of America. 111: 13361-6. PMID 25157146 DOI: 10.1073/pnas.1407293111  0.4
2014 Wang I, Kowalski MP, Langley AR, Rodriguez R, Balasubramanian S, Hsu ST, Krude T. Nucleotide contributions to the structural integrity and DNA replication initiation activity of noncoding y RNA. Biochemistry. 53: 5848-63. PMID 25151917 DOI: 10.1021/bi500470b  1
2014 Biffi G, Tannahill D, Miller J, Howat WJ, Balasubramanian S. Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues. Plos One. 9: e102711. PMID 25033211 DOI: 10.1371/journal.pone.0102711  1
2014 Balasubramanian S. Chemical biology on the genome. Bioorganic & Medicinal Chemistry. 22: 4356-70. PMID 24957879 DOI: 10.1016/j.bmc.2014.05.016  1
2014 Sulakhe D, Taylor A, Balasubramanian S, Feng B, Xie B, Börnigen D, Dave UJ, Foster IT, Gilliam TC, Maltsev N. Lynx web services for annotations and systems analysis of multi-gene disorders. Nucleic Acids Research. 42: W473-7. PMID 24948611 DOI: 10.1093/nar/gku517  0.32
2014 Booth MJ, Marsico G, Bachman M, Beraldi D, Balasubramanian S. Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution. Nature Chemistry. 6: 435-40. PMID 24755596 DOI: 10.1038/nchem.1893  1
2014 Di Antonio M, McLuckie KI, Balasubramanian S. Reprogramming the mechanism of action of chlorambucil by coupling to a G-quadruplex ligand. Journal of the American Chemical Society. 136: 5860-3. PMID 24697838 DOI: 10.1021/ja5014344  1
2014 Murat P, Zhong J, Lekieffre L, Cowieson NP, Clancy JL, Preiss T, Balasubramanian S, Khanna R, Tellam J. G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation. Nature Chemical Biology. 10: 358-64. PMID 24633353 DOI: 10.1038/nchembio.1479  1
2014 Murat P, Balasubramanian S. Existence and consequences of G-quadruplex structures in DNA. Current Opinion in Genetics & Development. 25: 22-9. PMID 24584093 DOI: 10.1016/j.gde.2013.10.012  1
2014 Nasiri HR, Bell NM, McLuckie KI, Husby J, Abell C, Neidle S, Balasubramanian S. Targeting a c-MYC G-quadruplex DNA with a fragment library. Chemical Communications (Cambridge, England). 50: 1704-7. PMID 24394582 DOI: 10.1039/c3cc48390h  1
2014 Biffi G, Di Antonio M, Tannahill D, Balasubramanian S. Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nature Chemistry. 6: 75-80. PMID 24345950 DOI: 10.1038/nchem.1805  1
2013 Bell NM, L'Hernault A, Murat P, Richards JE, Lever AM, Balasubramanian S. Targeting RNA-protein interactions within the human immunodeficiency virus type 1 lifecycle. Biochemistry. 52: 9269-74. PMID 24358934 DOI: 10.1021/bi401270d  1
2013 Wu L, Murat P, Matak-Vinkovic D, Murrell A, Balasubramanian S. Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins. Biochemistry. 52: 9519-27. PMID 24320048 DOI: 10.1021/bi401085h  1
2013 Iurlaro M, Ficz G, Oxley D, Raiber EA, Bachman M, Booth MJ, Andrews S, Balasubramanian S, Reik W. A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biology. 14: R119. PMID 24156278 DOI: 10.1186/gb-2013-14-10-r119  1
2013 Yangyuoru PM, Zhang AY, Shi Z, Koirala D, Balasubramanian S, Mao H. Mechanochemical properties of individual human telomeric RNA (TERRA) G-quadruplexes. Chembiochem : a European Journal of Chemical Biology. 14: 1931-5. PMID 24038851 DOI: 10.1002/cbic.201300350  1
2013 Booth MJ, Ost TW, Beraldi D, Bell NM, Branco MR, Reik W, Balasubramanian S. Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine. Nature Protocols. 8: 1841-51. PMID 24008380 DOI: 10.1038/nprot.2013.115  1
2013 Murat P, Gormally MV, Sanders D, Di Antonio M, Balasubramanian S. Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand. Chemical Communications (Cambridge, England). 49: 8453-5. PMID 23949446 DOI: 10.1039/c3cc44737e  1
2013 Balasubramanian S, Wang P, Schaller RD, Rajh T, Rozhkova EA. High-performance bioassisted nanophotocatalyst for hydrogen production. Nano Letters. 13: 3365-71. PMID 23808953 DOI: 10.1021/nl4016655  0.76
2013 McLuckie KI, Di Antonio M, Zecchini H, Xian J, Caldas C, Krippendorff BF, Tannahill D, Lowe C, Balasubramanian S. G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells. Journal of the American Chemical Society. 135: 9640-3. PMID 23782415 DOI: 10.1021/ja404868t  1
2013 Lam EY, Beraldi D, Tannahill D, Balasubramanian S. G-quadruplex structures are stable and detectable in human genomic DNA. Nature Communications. 4: 1796. PMID 23653208 DOI: 10.1038/ncomms2792  1
2013 Biffi G, Tannahill D, McCafferty J, Balasubramanian S. Quantitative visualization of DNA G-quadruplex structures in human cells. Nature Chemistry. 5: 182-6. PMID 23422559 DOI: 10.1038/nchem.1548  1
2013 Mitchell T, Ramos-Montoya A, Di Antonio M, Murat P, Ohnmacht S, Micco M, Jurmeister S, Fryer L, Balasubramanian S, Neidle S, Neal DE. Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer. Biochemistry. 52: 1429-36. PMID 23363071 DOI: 10.1021/bi301349c  1
2013 Kim DH, Vitol EA, Liu J, Balasubramanian S, Gosztola DJ, Cohen EE, Novosad V, Rozhkova EA. Stimuli-responsive magnetic nanomicelles as multifunctional heat and cargo delivery vehicles. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 7425-32. PMID 23351096 DOI: 10.1021/la3044158  0.76
2013 Sanders DA, Ross-Innes CS, Beraldi D, Carroll JS, Balasubramanian S. Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells. Genome Biology. 14: R6. PMID 23347430 DOI: 10.1186/gb-2013-14-1-r6  0.44
2013 Nikan M, Di Antonio M, Abecassis K, McLuckie K, Balasubramanian S. An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel G-quadruplexes. Angewandte Chemie (International Ed. in English). 52: 1428-31. PMID 23238938 DOI: 10.1002/anie.201207075  1
2012 Bugaut A, Murat P, Balasubramanian S. An RNA hairpin to G-quadruplex conformational transition. Journal of the American Chemical Society. 134: 19953-6. PMID 23190255 DOI: 10.1021/ja308665g  1
2012 Zhang AY, Balasubramanian S. The kinetics and folding pathways of intramolecular G-quadruplex nucleic acids. Journal of the American Chemical Society. 134: 19297-308. PMID 23113843 DOI: 10.1021/ja309851t  1
2012 Di Antonio M, Biffi G, Mariani A, Raiber EA, Rodriguez R, Balasubramanian S. Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry. Angewandte Chemie (International Ed. in English). 51: 11073-8. PMID 23038154 DOI: 10.1002/anie.201206281  1
2012 Raiber EA, Beraldi D, Ficz G, Burgess HE, Branco MR, Murat P, Oxley D, Booth MJ, Reik W, Balasubramanian S. Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biology. 13: R69. PMID 22902005 DOI: 10.1186/gb-2012-13-8-r69  1
2012 Müller S, Sanders DA, Di Antonio M, Matsis S, Riou JF, Rodriguez R, Balasubramanian S. Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. Organic & Biomolecular Chemistry. 10: 6537-46. PMID 22790277 DOI: 10.1039/c2ob25830g  1
2012 Biffi G, Tannahill D, Balasubramanian S. An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2. Journal of the American Chemical Society. 134: 11974-6. PMID 22780456 DOI: 10.1021/ja305734x  1
2012 Booth MJ, Branco MR, Ficz G, Oxley D, Krueger F, Reik W, Balasubramanian S. Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science (New York, N.Y.). 336: 934-7. PMID 22539555 DOI: 10.1126/science.1220671  1
2012 Bell NM, Kenyon JC, Balasubramanian S, Lever AM. Comparative structural effects of HIV-1 Gag and nucleocapsid proteins in binding to and unwinding of the viral RNA packaging signal. Biochemistry. 51: 3162-9. PMID 22448757 DOI: 10.1021/bi2017969  1
2012 Bugaut A, Balasubramanian S. 5'-UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Research. 40: 4727-41. PMID 22351747 DOI: 10.1093/nar/gks068  1
2012 Di Antonio M, Rodriguez R, Balasubramanian S. Experimental approaches to identify cellular G-quadruplex structures and functions. Methods (San Diego, Calif.). 57: 84-92. PMID 22343041 DOI: 10.1016/j.ymeth.2012.01.008  1
2012 Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nature Chemical Biology. 8: 301-10. PMID 22306580 DOI: 10.1038/nchembio.780  1
2012 Mela I, Kranaster R, Henderson RM, Balasubramanian S, Edwardson JM. Demonstration of ligand decoration, and ligand-induced perturbation, of G-quadruplexes in a plasmid using atomic force microscopy. Biochemistry. 51: 578-85. PMID 22225525 DOI: 10.1021/bi201600g  1
2012 Dash J, Das RN, Hegde N, PantoÅŸ GD, Shirude PS, Balasubramanian S. Synthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 554-64. PMID 22161991 DOI: 10.1002/chem.201102556  1
2012 Sarkies P, Murat P, Phillips LG, Patel KJ, Balasubramanian S, Sale JE. FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Research. 40: 1485-98. PMID 22021381 DOI: 10.1093/nar/gkr868  1
2012 Raiber EA, Kranaster R, Lam E, Nikan M, Balasubramanian S. A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro. Nucleic Acids Research. 40: 1499-508. PMID 22021377 DOI: 10.1093/nar/gkr882  1
2011 Balasubramanian S. Decoding genomes at high speed: implications for science and medicine. Angewandte Chemie (International Ed. in English). 50: 12406-10. PMID 22144295 DOI: 10.1002/anie.201106707  1
2011 Koirala D, Dhakal S, Ashbridge B, Sannohe Y, Rodriguez R, Sugiyama H, Balasubramanian S, Mao H. A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. Nature Chemistry. 3: 782-7. PMID 21941250 DOI: 10.1038/nchem.1126  1
2011 Hegde NS, Sanders DA, Rodriguez R, Balasubramanian S. The transcription factor FOXM1 is a cellular target of the natural product thiostrepton. Nature Chemistry. 3: 725-31. PMID 21860463 DOI: 10.1038/nchem.1114  1
2011 Lightfoot HL, Bugaut A, Armisen J, Lehrbach NJ, Miska EA, Balasubramanian S. A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing. Biochemistry. 50: 7514-21. PMID 21815640 DOI: 10.1021/bi200851d  1
2011 Zhang AY, Bugaut A, Balasubramanian S. A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology. Biochemistry. 50: 7251-8. PMID 21744844 DOI: 10.1021/bi200805j  1
2011 Balasubramanian S. Sequencing nucleic acids: from chemistry to medicine. Chemical Communications (Cambridge, England). 47: 7281-6. PMID 21544287 DOI: 10.1039/c1cc11078k  1
2011 Kagan D, Campuzano S, Balasubramanian S, Kuralay F, Flechsig GU, Wang J. Functionalized micromachines for selective and rapid isolation of nucleic acid targets from complex samples. Nano Letters. 11: 2083-7. PMID 21491941 DOI: 10.1021/nl2005687  0.76
2011 Balasubramanian S, Kagan D, Hu CM, Campuzano S, Lobo-Castañon MJ, Lim N, Kang DY, Zimmerman M, Zhang L, Wang J. Micromachine-enabled capture and isolation of cancer cells in complex media. Angewandte Chemie (International Ed. in English). 50: 4161-4. PMID 21472835 DOI: 10.1002/anie.201100115  0.76
2011 Balasubramanian S, Hurley LH, Neidle S. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? Nature Reviews. Drug Discovery. 10: 261-75. PMID 21455236 DOI: 10.1038/nrd3428  1
2011 Smith JS, Chen Q, Yatsunyk LA, Nicoludis JM, Garcia MS, Kranaster R, Balasubramanian S, Monchaud D, Teulade-Fichou MP, Abramowitz L, Schultz DC, Johnson FB. Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae. Nature Structural & Molecular Biology. 18: 478-85. PMID 21399640 DOI: 10.1038/nsmb.2033  1
2011 Dash J, Waller ZA, Panto? GD, Balasubramanian S. Synthesis and binding studies of novel diethynyl-pyridine amides with genomic promoter DNA G-quadruplexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 4571-81. PMID 21387430 DOI: 10.1002/chem.201003157  1
2011 McLuckie KI, Waller ZA, Sanders DA, Alves D, Rodriguez R, Dash J, McKenzie GJ, Venkitaraman AR, Balasubramanian S. G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells. Journal of the American Chemical Society. 133: 2658-63. PMID 21294544 DOI: 10.1021/ja109474c  1
2011 Kagan D, Balasubramanian S, Wang J. Chemically triggered swarming of gold microparticles. Angewandte Chemie (International Ed. in English). 50: 503-6. PMID 21140389 DOI: 10.1002/anie.201005078  0.76
2010 Bejugam M, Gunaratnam M, Müller S, Sanders DA, Sewitz S, Fletcher JA, Neidle S, Balasubramanian S. Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines. Acs Medicinal Chemistry Letters. 1: 306-10. PMID 24900212 DOI: 10.1021/ml100062z  0.56
2010 Müller S, Kumari S, Rodriguez R, Balasubramanian S. Small-molecule-mediated G-quadruplex isolation from human cells. Nature Chemistry. 2: 1095-8. PMID 21107376 DOI: 10.1038/nchem.842  1
2010 Kagan D, Laocharoensuk R, Zimmerman M, Clawson C, Balasubramanian S, Kang D, Bishop D, Sattayasamitsathit S, Zhang L, Wang J. Rapid delivery of drug carriers propelled and navigated by catalytic nanoshuttles. Small (Weinheim An Der Bergstrasse, Germany). 6: 2741-7. PMID 20979242 DOI: 10.1002/smll.201001257  0.76
2010 Wu J, Balasubramanian S, Kagan D, Manesh KM, Campuzano S, Wang J. Motion-based DNA detection using catalytic nanomotors. Nature Communications. 1: 36. PMID 20975708 DOI: 10.1038/ncomms1035  0.76
2010 Marnef A, Maldonado M, Bugaut A, Balasubramanian S, Kress M, Weil D, Standart N. Distinct functions of maternal and somatic Pat1 protein paralogs. Rna (New York, N.Y.). 16: 2094-107. PMID 20826699 DOI: 10.1261/rna.2295410  1
2010 Shahid R, Bugaut A, Balasubramanian S. The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression. Biochemistry. 49: 8300-6. PMID 20726580 DOI: 10.1021/bi100957h  1
2010 Manesh KM, Balasubramanian S, Wang J. Nanomotor-based 'writing' of surface microstructures. Chemical Communications (Cambridge, England). 46: 5704-6. PMID 20589286 DOI: 10.1039/c0cc00178c  0.76
2010 Bugaut A, Rodriguez R, Kumari S, Hsu ST, Balasubramanian S. Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex. Organic & Biomolecular Chemistry. 8: 2771-6. PMID 20436976 DOI: 10.1039/c002418j  1
2010 Manesh KM, Cardona M, Yuan R, Clark M, Kagan D, Balasubramanian S, Wang J. Template-assisted fabrication of salt-independent catalytic tubular microengines. Acs Nano. 4: 1799-804. PMID 20230041 DOI: 10.1021/nn1000468  0.76
2010 Calvo-Marzal P, Sattayasamitsathit S, Balasubramanian S, Windmiller JR, Dao C, Wang J. Propulsion of nanowire diodes. Chemical Communications (Cambridge, England). 46: 1623-4. PMID 20177595 DOI: 10.1039/b925568k  0.76
2010 Yeoman JA, Orte A, Ashbridge B, Klenerman D, Balasubramanian S. RNA conformation in catalytically active human telomerase. Journal of the American Chemical Society. 132: 2852-3. PMID 20148555 DOI: 10.1021/ja909383n  1
2010 Fegan A, Shirude PS, Ying L, Balasubramanian S. Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes. Chemical Communications (Cambridge, England). 46: 946-8. PMID 20107659 DOI: 10.1039/b920680a  1
2010 Bejugam M, Gunaratnam M, Müller S, Sanders DA, Sewitz S, Fletcher JA, Neidle S, Balasubramanian S. Targeting the c-Kit promoter g-quadruplexes with 6-substituted indenoisoquinolines Acs Medicinal Chemistry Letters. 1: 306-310. DOI: 10.1021/ml100062z  1
2009 Ashbridge B, Orte A, Yeoman JA, Kirwan M, Vulliamy T, Dokal I, Klenerman D, Balasubramanian S. Single-molecule analysis of the human telomerase RNA.dyskerin interaction and the effect of dyskeratosis congenita mutations. Biochemistry. 48: 10858-65. PMID 19835419 DOI: 10.1021/bi901373e  1
2009 Fernando H, Sewitz S, Darot J, Tavaré S, Huppert JL, Balasubramanian S. Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression. Nucleic Acids Research. 37: 6716-22. PMID 19745055 DOI: 10.1093/nar/gkp740  1
2009 Lehrbach NJ, Armisen J, Lightfoot HL, Murfitt KJ, Bugaut A, Balasubramanian S, Miska EA. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Nature Structural & Molecular Biology. 16: 1016-20. PMID 19713957 DOI: 10.1038/nsmb.1675  1
2009 Hsu STD, Varnai P, Bugaut A, Reszka AP, Neidle S, Balasubramanian S. A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics Journal of the American Chemical Society. 131: 13399-13409. PMID 19705869 DOI: 10.1021/ja904007p  1
2009 Waller ZA, Sewitz SA, Hsu ST, Balasubramanian S. A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression. Journal of the American Chemical Society. 131: 12628-33. PMID 19689109 DOI: 10.1021/ja901892u  1
2009 Jena PV, Shirude PS, Okumus B, Laxmi-Reddy K, Godde F, Huc I, Balasubramanian S, Ha T. G-quadruplex DNA bound by a synthetic ligand is highly dynamic. Journal of the American Chemical Society. 131: 12522-3. PMID 19685880 DOI: 10.1021/ja903408r  1
2009 Kagan D, Calvo-Marzal P, Balasubramanian S, Sattayasamitsathit S, Manesh KM, Flechsig GU, Wang J. Chemical sensing based on catalytic nanomotors: motion-based detection of trace silver. Journal of the American Chemical Society. 131: 12082-3. PMID 19670862 DOI: 10.1021/ja905142q  0.76
2009 Calvo-Marzal P, Manesh KM, Kagan D, Balasubramanian S, Cardona M, Flechsig GU, Posner J, Wang J. Electrochemically-triggered motion of catalytic nanomotors. Chemical Communications (Cambridge, England). 4509-11. PMID 19617966 DOI: 10.1039/b909227g  0.76
2009 Balasubramanian S, Neidle S. G-quadruplex nucleic acids as therapeutic targets Current Opinion in Chemical Biology. 13: 345-353. PMID 19515602 DOI: 10.1016/j.cbpa.2009.04.637  1
2009 Balasubramanian S, Kagan D, Manesh KM, Calvo-Marzal P, Flechsig GU, Wang J. Thermal modulation of nanomotor movement. Small (Weinheim An Der Bergstrasse, Germany). 5: 1569-74. PMID 19326356 DOI: 10.1002/smll.200900023  0.76
2009 Müller S, Panto? GD, Rodriguez R, Balasubramanian S. Controlled-folding of a small molecule modulates DNA G-quadruplex recognition. Chemical Communications (Cambridge, England). 80-2. PMID 19082005 DOI: 10.1039/b816861j  1
2009 Redman JE, Granadino-Roldán JM, Schouten JA, Ladame S, Reszka AP, Neidle S, Balasubramanian S. Recognition and discrimination of DNA quadruplexes by acridine-peptide conjugates. Organic & Biomolecular Chemistry. 7: 76-84. PMID 19081949 DOI: 10.1039/b814682a  1
2008 Kumari S, Bugaut A, Balasubramanian S. Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene. Biochemistry. 47: 12664-9. PMID 18991403 DOI: 10.1021/bi8010797  1
2008 Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, Hall KP, Evers DJ, Barnes CL, Bignell HR, Boutell JM, Bryant J, Carter RJ, Keira Cheetham R, Cox AJ, et al. Accurate whole human genome sequencing using reversible terminator chemistry. Nature. 456: 53-9. PMID 18987734 DOI: 10.1038/nature07517  1
2008 Dash J, Shirude PS, Hsu ST, Balasubramanian S. Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes. Journal of the American Chemical Society. 130: 15950-6. PMID 18980309 DOI: 10.1021/ja8046552  1
2008 London TB, Barber LJ, Mosedale G, Kelly GP, Balasubramanian S, Hickson ID, Boulton SJ, Hiom K. FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. The Journal of Biological Chemistry. 283: 36132-9. PMID 18978354 DOI: 10.1074/jbc.M808152200  1
2008 Rodriguez R, Müller S, Yeoman JA, Trentesaux C, Riou JF, Balasubramanian S. A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres. Journal of the American Chemical Society. 130: 15758-9. PMID 18975896 DOI: 10.1021/ja805615w  1
2008 Huppert JL, Bugaut A, Kumari S, Balasubramanian S. G-quadruplexes: the beginning and end of UTRs. Nucleic Acids Research. 36: 6260-8. PMID 18832370 DOI: 10.1093/nar/gkn511  1
2008 Fernando H, Rodriguez R, Balasubramanian S. Selective recognition of a DNA G-quadruplex by an engineered antibody. Biochemistry. 47: 9365-71. PMID 18702511 DOI: 10.1021/bi800983u  1
2008 Dash J, Shirude PS, Balasubramanian S. G-quadruplex recognition by bis-indole carboxamides. Chemical Communications (Cambridge, England). 3055-7. PMID 18688346 DOI: 10.1039/b806042h  1
2008 Shirude PS, Ying L, Balasubramanian S. Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC. Chemical Communications (Cambridge, England). 2007-9. PMID 18536803 DOI: 10.1039/b801465e  1
2008 Fegan A, Shirude PS, Balasubramanian S. Rigid cyanine dye nucleic acid labels. Chemical Communications (Cambridge, England). 2004-6. PMID 18536802 DOI: 10.1039/b801629a  1
2008 Nepal D, Balasubramanian S, Simonian AL, Davis VA. Strong antimicrobial coatings: single-walled carbon nanotubes armored with biopolymers. Nano Letters. 8: 1896-901. PMID 18507479 DOI: 10.1021/nl080522t  0.32
2008 Alves D, Li H, Codrington R, Orte A, Ren X, Klenerman D, Balasubramanian S. Single-molecule analysis of human telomerase monomer. Nature Chemical Biology. 4: 287-9. PMID 18391947 DOI: 10.1038/nchembio.82  1
2008 Waller ZA, Shirude PS, Rodriguez R, Balasubramanian S. Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition. Chemical Communications (Cambridge, England). 1467-9. PMID 18338058 DOI: 10.1039/b718854d  0.64
2008 Bugaut A, Jantos K, Wietor JL, Rodriguez R, Sanders JK, Balasubramanian S. Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry. Angewandte Chemie (International Ed. in English). 47: 2677-80. PMID 18300215 DOI: 10.1002/anie.200705589  0.48
2008 Shirude PS, Balasubramanian S. Single molecule conformational analysis of DNA G-quadruplexes. Biochimie. 90: 1197-206. PMID 18295608 DOI: 10.1016/j.biochi.2008.01.015  1
2007 Balasubramanian S. Massively parallel synthetic sequencing of DNA on clonal arrays. Nucleic Acids Symposium Series (2004). 107. PMID 18029609 DOI: 10.1093/nass/nrm054  1
2007 Bejugam M, Sewitz S, Shirude PS, Rodriguez R, Shahid R, Balasubramanian S. Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. Journal of the American Chemical Society. 129: 12926-7. PMID 17918848 DOI: 10.1021/ja075881p  0.64
2007 Shirude PS, Gillies ER, Ladame S, Godde F, Shin-Ya K, Huc I, Balasubramanian S. Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. Journal of the American Chemical Society. 129: 11890-1. PMID 17845042 DOI: 10.1021/ja073775h  1
2007 Balasubramanian S. From DNA to mountain climbing. Shankar Balasubramanian talks to Alison Stoddart about his research and other interests. Molecular Biosystems. 3: B37. PMID 17582897  1
2007 Rodriguez R, Panto? GD, Gonçalves DP, Sanders JK, Balasubramanian S. Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction. Angewandte Chemie (International Ed. in English). 46: 5405-7. PMID 17562537 DOI: 10.1002/anie.200605075  0.48
2007 Shirude PS, Okumus B, Ying L, Ha T, Balasubramanian S. Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. Journal of the American Chemical Society. 129: 7484-5. PMID 17523641 DOI: 10.1021/ja070497d  1
2007 Nanduri V, Balasubramanian S, Sista S, Vodyanoy VJ, Simonian AL. Highly sensitive phage-based biosensor for the detection of beta-galactosidase. Analytica Chimica Acta. 589: 166-72. PMID 17418177 DOI: 10.1016/j.aca.2007.02.071  0.32
2007 Wei D, Oyarzabal OA, Huang TS, Balasubramanian S, Sista S, Simonian AL. Development of a surface plasmon resonance biosensor for the identification of Campylobacter jejuni. Journal of Microbiological Methods. 69: 78-85. PMID 17258830 DOI: 10.1016/j.mimet.2006.12.002  0.32
2007 Luckarift HR, Balasubramanian S, Paliwal S, Johnson GR, Simonian AL. Enzyme-encapsulated silica monolayers for rapid functionalization of a gold surface. Colloids and Surfaces. B, Biointerfaces. 58: 28-33. PMID 16996252 DOI: 10.1016/j.colsurfb.2006.08.013  0.32
2007 Balasubramanian S, Sorokulova IB, Vodyanoy VJ, Simonian AL. Lytic phage as a specific and selective probe for detection of Staphylococcus aureus--A surface plasmon resonance spectroscopic study. Biosensors & Bioelectronics. 22: 948-55. PMID 16697635 DOI: 10.1016/j.bios.2006.04.003  0.32
2006 Gonçalves DP, Rodriguez R, Balasubramanian S, Sanders JK. Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands. Chemical Communications (Cambridge, England). 4685-7. PMID 17109036 DOI: 10.1039/b611731g  0.48
2006 Orte A, Clarke R, Balasubramanian S, Klenerman D. Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection. Analytical Chemistry. 78: 7707-15. PMID 17105162 DOI: 10.1021/ac061122y  1
2006 Redman JE, Ladame S, Reszka AP, Neidle S, Balasubramanian S. Discovery of G-quadruplex stabilizing ligands through direct ELISA of a one-bead-one-compound library. Organic & Biomolecular Chemistry. 4: 4364-9. PMID 17102882 DOI: 10.1039/b611716c  1
2006 Gavory G, Symmons MF, Krishnan Ghosh Y, Klenerman D, Balasubramanian S. Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling. Biochemistry. 45: 13304-11. PMID 17073451 DOI: 10.1021/bi061150a  1
2006 White SS, Balasubramanian S, Klenerman D, Ying L. A simple nanomixer for single-molecule kinetics measurements. Angewandte Chemie (International Ed. in English). 45: 7540-3. PMID 17051625 DOI: 10.1002/anie.200602289  1
2006 Jantos K, Rodriguez R, Ladame S, Shirude PS, Balasubramanian S. Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands. Journal of the American Chemical Society. 128: 13662-3. PMID 17044674 DOI: 10.1021/ja064713e  0.64
2006 Gonçalves DP, Ladame S, Balasubramanian S, Sanders JK. Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins. Organic & Biomolecular Chemistry. 4: 3337-42. PMID 17036123 DOI: 10.1039/b608494j  0.6
2006 Green JJ, Ladame S, Ying L, Klenerman D, Balasubramanian S. Investigating a quadruplex-ligand interaction by unfolding kinetics. Journal of the American Chemical Society. 128: 9809-12. PMID 16866537 DOI: 10.1021/ja0615425  1
2006 Fernando H, Reszka AP, Huppert J, Ladame S, Rankin S, Venkitaraman AR, Neidle S, Balasubramanian S. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Biochemistry. 45: 7854-60. PMID 16784237 DOI: 10.1021/bi0601510  1
2006 Ren X, Li H, Clarke RW, Alves DA, Ying L, Klenerman D, Balasubramanian S. Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy. Journal of the American Chemical Society. 128: 4992-5000. PMID 16608333 DOI: 10.1021/ja056613z  1
2006 Liu D, Bruckbauer A, Abell C, Balasubramanian S, Kang DJ, Klenerman D, Zhou D. A reversible pH-driven DNA nanoswitch array. Journal of the American Chemical Society. 128: 2067-71. PMID 16464109 DOI: 10.1021/ja0568300  1
2006 Ladame S, Schouten JA, Roldan J, Redman JE, Neidle S, Balasubramanian S. Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein. Biochemistry. 45: 1393-9. PMID 16445281 DOI: 10.1021/bi050229x  1
2005 Shu W, Liu D, Watari M, Riener CK, Strunz T, Welland ME, Balasubramanian S, McKendry RA. DNA molecular motor driven micromechanical cantilever arrays. Journal of the American Chemical Society. 127: 17054-60. PMID 16316252 DOI: 10.1021/ja0554514  1
2005 Krishnan-Ghosh Y, Stephens E, Balasubramanian S. PNA forms an i-motif. Chemical Communications (Cambridge, England). 5278-80. PMID 16244727 DOI: 10.1039/b510405j  0.56
2005 Ladame S, Whitney AM, Balasubramanian S. Targeting nucleic acid secondary structures with polyamides using an optimized dynamic combinatorial approach. Angewandte Chemie (International Ed. in English). 44: 5736-9. PMID 16078284 DOI: 10.1002/anie.200501450  0.6
2005 Rankin S, Reszka AP, Huppert J, Zloh M, Parkinson GN, Todd AK, Ladame S, Balasubramanian S, Neidle S. Putative DNA quadruplex formation within the human c-kit oncogene. Journal of the American Chemical Society. 127: 10584-9. PMID 16045346 DOI: 10.1021/ja050823u  1
2005 Krishnan-Ghosh Y, Whitney AM, Balasubramanian S. Dynamic covalent chemistry on self-templating PNA oligomers: formation of a bimolecular PNA quadruplex. Chemical Communications (Cambridge, England). 3068-70. PMID 15959587 DOI: 10.1039/b503578c  0.6
2005 Mason SJ, Hake JL, Nairne J, Cummins WJ, Balasubramanian S. Solid-phase methods for the synthesis of cyanine dyes. The Journal of Organic Chemistry. 70: 2939-49. PMID 15822952 DOI: 10.1021/jo0479415  1
2004 Patel SD, Isalan M, Gavory G, Ladame S, Choo Y, Balasubramanian S. Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes. Biochemistry. 43: 13452-8. PMID 15491152 DOI: 10.1021/bi048892t  1
2004 Ladame S, Schouten JA, Stuart J, Roldan J, Neidle S, Balasubramanian S. Tetrapeptides induce selective recognition for G-quadruplexes when conjugated to a DNA-binding platform. Organic & Biomolecular Chemistry. 2: 2925-31. PMID 15480456 DOI: 10.1039/B409698C  1
2004 Krishnan-Ghosh Y, Liu D, Balasubramanian S. Formation of an interlocked quadruplex dimer by d(GGGT). Journal of the American Chemical Society. 126: 11009-16. PMID 15339186 DOI: 10.1021/ja049259y  1
2004 Shammas MA, Liu X, Gavory G, Raney KD, Balasubramanian S, Shmookler Reis RJ. Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells. Experimental Cell Research. 295: 204-14. PMID 15051503 DOI: 10.1016/j.yexcr.2004.01.003  1
2004 Whitney AM, Ladame S, Balasubramanian S. Templated ligand assembly by using G-quadruplex DNA and dynamic covalent chemistry. Angewandte Chemie (International Ed. in English). 43: 1143-6. PMID 14983458 DOI: 10.1002/anie.200353069  0.6
2003 Liu D, Balasubramanian S. A proton-fuelled DNA nanomachine. Angewandte Chemie (International Ed. in English). 42: 5734-6. PMID 14661209 DOI: 10.1002/anie.200352402  1
2003 Schouten JA, Ladame S, Mason SJ, Cooper MA, Balasubramanian S. G-quadruplex-specific peptide-hemicyanine ligands by partial combinatorial selection. Journal of the American Chemical Society. 125: 5594-5. PMID 12733873 DOI: 10.1021/ja029356w  1
2002 Mason SJ, Balasubramanian S. Solid-phase catch, activate, and release synthesis of cyanine dyes. Organic Letters. 4: 4261-4. PMID 12443073 DOI: 10.1021/ol026836j  1
2002 Gavory G, Farrow M, Balasubramanian S. Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro. Nucleic Acids Research. 30: 4470-80. PMID 12384594  1
2002 Ladame S, Harrison RJ, Neidle S, Balasubramanian S. Solid-phase synthesis of symmetrical 3,6-bispeptide-acridone conjugates. Organic Letters. 4: 2509-12. PMID 12123363 DOI: 10.1021/ol026130p  1
2000 Liu X, Balasubramanian S. Strategies for the synthesis of fluorescently labelled PNA. Tetrahedron Letters. 41: 6153-6156. PMID 18259605  1
1999 Harrison JG, Liu X, Balasubramanian S. Screening for oligonucleotide binding affinity by a convenient fluorescence competition assay. Nucleic Acids Research. 27: e14. PMID 10446257  1
1999 Harrison JG, Frier C, Laurant R, Dennis R, Raney KD, Balasubramanian S. Inhibition of human telomerase by PNA-cationic peptide conjugates. Bioorganic & Medicinal Chemistry Letters. 9: 1273-8. PMID 10340613 DOI: 10.1016/S0960-894X(99)00170-5  1
1995 Bornemann S, Balasubramanian S, Coggins JR, Abell C, Lowe DJ, Thorneley RN. Escherichia coli chorismate synthase: a deuterium kinetic-isotope effect under single-turnover and steady-state conditions shows that a flavin intermediate forms before the C-(6proR)-H bond is cleaved. The Biochemical Journal. 305: 707-10. PMID 7848266  0.6
1995 Balasubramanian S, Coggins JR, Abell C. Observation of a secondary tritium isotope effect in the chorismate synthase reaction. Biochemistry. 34: 341-8. PMID 7819217  0.6
1995 Carr RT, Balasubramanian S, Hawkins PC, Benkovic SJ. Mechanism of metal-independent hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase. Biochemistry. 34: 7525-32. PMID 7779797  0.44
1995 Bornemann S, Ramjee MK, Balasubramanian S, Abell C, Coggins JR, Lowe DJ, Thorneley RN. Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate. The Journal of Biological Chemistry. 270: 22811-5. PMID 7559411  0.6
1994 Balasubramanian S, Carr RT, Bender CJ, Peisach J, Benkovic SJ. Identification of metal ligands in Cu(II)-inhibited Chromobacterium violaceum phenylalanine hydroxylase by electron spin echo envelope modulation analysis of histidine to serine mutations. Biochemistry. 33: 8532-7. PMID 8031788  1
1994 Peliska JA, Balasubramanian S, Giedroc DP, Benkovic SJ. Recombinant HIV-1 nucleocapsid protein accelerates HIV-1 reverse transcriptase catalyzed DNA strand transfer reactions and modulates RNase H activity. Biochemistry. 33: 13817-23. PMID 7524664  0.44
1993 Balasubramanian S, Carr RT, Bender CJ, Peisach J, Benkovic SJ. Histidines 138 and 143 are copper binding ligands in Chromobacterium violaceum phenylalanine hydroxylase. Advances in Experimental Medicine and Biology. 338: 67-70. PMID 8304204  1
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