| Year |
Citation |
Score |
| 2024 |
Balasubramanian S, Yan T, Chen Y, Mortishire-Smith B, Simeone A, Hofer A. Selective Photocatalytic C-H oxidation of 5-methylcytosine in DNA. Angewandte Chemie (International Ed. in English). e202413593. PMID 39231378 DOI: 10.1002/anie.202413593 |
0.313 |
|
| 2024 |
Flynn SM, Dhir S, Herka K, Doyle C, Melidis L, Simeone A, Hui WWI, Araujo Tavares RC, Schoenfelder S, Tannahill D, Balasubramanian S. Improved simultaneous mapping of epigenetic features and 3D chromatin structure via ViCAR. Genome Biology. 25: 237. PMID 39227991 DOI: 10.1186/s13059-024-03377-6 |
0.821 |
|
| 2024 |
Carnie CJ, Acampora AC, Bader AS, Erdenebat C, Zhao S, Bitensky E, van den Heuvel D, Parnas A, Gupta V, D'Alessandro G, Sczaniecka-Clift M, Weickert P, Aygenli F, Götz MJ, Cordes J, ... ... Balasubramanian S, et al. Transcription-coupled repair of DNA-protein cross-links depends on CSA and CSB. Nature Cell Biology. PMID 38600235 DOI: 10.1038/s41556-024-01391-1 |
0.822 |
|
| 2024 |
Chen Y, Simeone A, Melidis L, Cuesta SM, Tannahill D, Balasubramanian S. An Upstream G-Quadruplex DNA Structure Can Stimulate Gene Transcription. Acs Chemical Biology. PMID 38417105 DOI: 10.1021/acschembio.3c00775 |
0.844 |
|
| 2024 |
Esain-Garcia I, Kirchner A, Melidis L, Tavares RCA, Dhir S, Simeone A, Yu Z, Madden SK, Hermann R, Tannahill D, Balasubramanian S. G-quadruplex DNA structure is a positive regulator of transcription. Proceedings of the National Academy of Sciences of the United States of America. 121: e2320240121. PMID 38315865 DOI: 10.1073/pnas.2320240121 |
0.852 |
|
| 2023 |
Serrano-Benitez A, Wells SE, Drummond-Clarke L, Russo LC, Thomas JC, Leal GA, Farrow M, Edgerton JM, Balasubramanian S, Yang M, Frezza C, Gautam A, Brazina J, Burdova K, Hoch NC, et al. Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity. The Embo Journal. e113190. PMID 37492888 DOI: 10.15252/embj.2022113190 |
0.593 |
|
| 2023 |
Mortishire-Smith BJ, Becker SM, Simeone A, Melidis L, Balasubramanian S. A Photoredox Reaction for the Selective Modification of 5-Carboxycytosine in DNA. Journal of the American Chemical Society. PMID 37141595 DOI: 10.1021/jacs.2c12558 |
0.802 |
|
| 2023 |
Füllgrabe J, Gosal WS, Creed P, Liu S, Lumby CK, Morley DJ, Ost TWB, Vilella AJ, Yu S, Bignell H, Burns P, Charlesworth T, Fu B, Fordham H, Harding NJ, ... ... Balasubramanian S, et al. Simultaneous sequencing of genetic and epigenetic bases in DNA. Nature Biotechnology. PMID 36747096 DOI: 10.1038/s41587-022-01652-0 |
0.309 |
|
| 2023 |
Yu Z, Spiegel J, Melidis L, Hui WWI, Zhang X, Radzevičius A, Balasubramanian S. Chem-map profiles drug binding to chromatin in cells. Nature Biotechnology. PMID 36690761 DOI: 10.1038/s41587-022-01636-0 |
0.811 |
|
| 2022 |
Galli S, Melidis L, Flynn SM, Varshney D, Simeone A, Spiegel J, Madden SK, Tannahill D, Balasubramanian S. DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody. Journal of the American Chemical Society. PMID 36488193 DOI: 10.1021/jacs.2c10656 |
0.849 |
|
| 2022 |
Hui WWI, Simeone A, Zyner KG, Tannahill D, Balasubramanian S. Publisher Correction: Single-cell mapping of DNA G-quadruplex structures in human cancer cells. Scientific Reports. 12: 908. PMID 35022562 DOI: 10.1038/s41598-022-05047-8 |
0.827 |
|
| 2022 |
Zyner KG, Simeone A, Flynn SM, Doyle C, Marsico G, Adhikari S, Portella G, Tannahill D, Balasubramanian S. G-quadruplex DNA structures in human stem cells and differentiation. Nature Communications. 13: 142. PMID 35013231 DOI: 10.1038/s41467-021-27719-1 |
0.838 |
|
| 2021 |
Hui WWI, Simeone A, Zyner KG, Tannahill D, Balasubramanian S. Single-cell mapping of DNA G-quadruplex structures in human cancer cells. Scientific Reports. 11: 23641. PMID 34880271 DOI: 10.1038/s41598-021-02943-3 |
0.844 |
|
| 2021 |
Varshney D, Cuesta SM, Herdy B, Abdullah UB, Tannahill D, Balasubramanian S. RNA G-quadruplex structures control ribosomal protein production. Scientific Reports. 11: 22735. PMID 34815422 DOI: 10.1038/s41598-021-01847-6 |
0.834 |
|
| 2021 |
Zhang X, Spiegel J, Martínez Cuesta S, Adhikari S, Balasubramanian S. Chemical profiling of DNA G-quadruplex-interacting proteins in live cells. Nature Chemistry. 13: 626-633. PMID 34183817 DOI: 10.1038/s41557-021-00736-9 |
0.387 |
|
| 2021 |
Shen J, Varshney D, Simeone A, Zhang X, Adhikari S, Tannahill D, Balasubramanian S. Promoter G-quadruplex folding precedes transcription and is controlled by chromatin. Genome Biology. 22: 143. PMID 33962653 DOI: 10.1186/s13059-021-02346-7 |
0.726 |
|
| 2021 |
Spiegel J, Cuesta SM, Adhikari S, Hänsel-Hertsch R, Tannahill D, Balasubramanian S. G-quadruplexes are transcription factor binding hubs in human chromatin. Genome Biology. 22: 117. PMID 33892767 DOI: 10.1186/s13059-021-02324-z |
0.825 |
|
| 2021 |
Broome R, Chernukhin I, Jamieson S, Kishore K, Papachristou EK, Mao SQ, Tejedo CG, Mahtey A, Theodorou V, Groen AJ, D'Santos C, Balasubramanian S, Farcas AM, Siersbæk R, Carroll JS. TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions. Cell Reports. 34: 108776. PMID 33626359 DOI: 10.1016/j.celrep.2021.108776 |
0.42 |
|
| 2020 |
Nappi M, Hofer A, Balasubramanian S, Gaunt MJ. Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis. Journal of the American Chemical Society. PMID 33305571 DOI: 10.1021/jacs.0c10616 |
0.509 |
|
| 2020 |
Xu YZ, Jenjaroenpun P, Wongsurawat T, Byrum SD, Shponka V, Tannahill D, Chavez EA, Hung SS, Steidl C, Balasubramanian S, Rimsza LM, Kendrick S. Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma. Nar Cancer. 2: zcaa029. PMID 33094287 DOI: 10.1093/narcan/zcaa029 |
0.694 |
|
| 2020 |
Spiegel J, Adhikari S, Balasubramanian S. The Structure and Function of DNA G-Quadruplexes. Trends in Chemistry. 2: 123-136. PMID 32923997 DOI: 10.1016/j.trechm.2019.07.002 |
0.449 |
|
| 2020 |
Hänsel-Hertsch R, Simeone A, Shea A, Hui WWI, Zyner KG, Marsico G, Rueda OM, Bruna A, Martin A, Zhang X, Adhikari S, Tannahill D, Caldas C, Balasubramanian S. Landscape of G-quadruplex DNA structural regions in breast cancer. Nature Genetics. PMID 32747825 DOI: 10.1038/S41588-020-0672-8 |
0.808 |
|
| 2020 |
Di Antonio M, Ponjavic A, Radzevičius A, Ranasinghe RT, Catalano M, Zhang X, Shen J, Needham LM, Lee SF, Klenerman D, Balasubramanian S. Single-molecule visualization of DNA G-quadruplex formation in live cells. Nature Chemistry. PMID 32690897 DOI: 10.1038/S41557-020-0506-4 |
0.463 |
|
| 2020 |
Mao SQ, Cuesta SM, Tannahill D, Balasubramanian S. Genome-wide DNA methylation signatures are determined by DNMT3A/B sequence preferences. Biochemistry. PMID 32543182 DOI: 10.1021/Acs.Biochem.0C00339.S001 |
0.757 |
|
| 2020 |
Varshney D, Spiegel J, Zyner K, Tannahill D, Balasubramanian S. The regulation and functions of DNA and RNA G-quadruplexes. Nature Reviews. Molecular Cell Biology. PMID 32313204 DOI: 10.1038/S41580-020-0236-X |
0.856 |
|
| 2020 |
Liu KC, Röder K, Mayer C, Adhikari S, Wales DJ, Balasubramanian S. Affinity-selected bicyclic peptide G-quadruplex ligands mimic a protein-like binding mechanism. Journal of the American Chemical Society. PMID 32267689 DOI: 10.1021/Jacs.0C01879 |
0.648 |
|
| 2020 |
Bilyard MK, Becker S, Balasubramanian S. Natural, modified DNA bases. Current Opinion in Chemical Biology. 57: 1-7. PMID 32145439 DOI: 10.1016/J.Cbpa.2020.01.014 |
0.4 |
|
| 2019 |
Sahakyan A, Mahtey A, Kawasaki F, Balasubramanian S. A Spontaneous Ring Opening Reaction Leads to a Repair-Resistant T Oxidation Product in Genomic DNA. Chembiochem : a European Journal of Chemical Biology. PMID 31386787 DOI: 10.1002/Cbic.201900484 |
0.784 |
|
| 2019 |
Zyner KG, Mulhearn DS, Adhikari S, Martínez Cuesta S, Di Antonio M, Erard N, Hannon GJ, Tannahill D, Balasubramanian S. Genetic interactions of G-quadruplexes in humans. Elife. 8. PMID 31287417 DOI: 10.7554/Elife.46793 |
0.837 |
|
| 2019 |
Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 20: 124. PMID 31215477 DOI: 10.1186/s13059-019-1737-9 |
0.793 |
|
| 2019 |
Liu ZJ, Martínez Cuesta S, van Delft P, Balasubramanian S. Sequencing abasic sites in DNA at single-nucleotide resolution. Nature Chemistry. 11: 629-637. PMID 31209299 DOI: 10.1038/S41557-019-0279-9 |
0.414 |
|
| 2019 |
Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d'Onofrio M, Balasubramanian S, Kouzarides T. METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Molecular Cell. PMID 31031083 DOI: 10.1016/J.Molcel.2019.03.040 |
0.546 |
|
| 2019 |
Shendure J, Balasubramanian S, Church GM, Gilbert W, Rogers J, Schloss JA, Waterston RH. Publisher Correction: DNA sequencing at 40: past, present and future. Nature. PMID 30948799 DOI: 10.1038/S41586-019-1120-8 |
0.304 |
|
| 2019 |
Hofer A, Liu ZJ, Balasubramanian S. The detection, structure and function of modified DNA bases. Journal of the American Chemical Society. PMID 30896931 DOI: 10.1021/Jacs.9B01915 |
0.345 |
|
| 2019 |
Marsico G, Chambers VS, Sahakyan AB, McCauley P, Boutell JM, Di Antonio M, Balasubramanian S. Whole genome experimental maps of DNA G-quadruplexes in multiple species. Nucleic Acids Research. PMID 30892612 DOI: 10.1093/Nar/Gkz179 |
0.814 |
|
| 2019 |
Nguyen HP, Stewart S, Kukwikila MN, Jones SF, Offenbartl-Stiegert D, Mao S, Balasubramanian S, Beck S, Howorka S. Opto-epigenetic modulation of DNA methylation with a photo-responsive small-molecule approach. Angewandte Chemie (International Ed. in English). PMID 30773767 DOI: 10.1002/Anie.201901139 |
0.588 |
|
| 2019 |
Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 20: 11. PMID 30635026 DOI: 10.1186/S13059-019-1623-5 |
0.792 |
|
| 2019 |
Zyner KG, Mulhearn DS, Adhikari S, Cuesta SM, Antonio MD, Erard N, Hannon GJ, Tannahill D, Balasubramanian S. Author response: Genetic interactions of G-quadruplexes in humans Elife. DOI: 10.7554/Elife.46793.033 |
0.664 |
|
| 2018 |
Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 19: 229. PMID 30591072 DOI: 10.1186/S13059-018-1602-2 |
0.806 |
|
| 2018 |
Sengar A, Vandana JJ, Chambers VS, Di Antonio M, Winnerdy FR, Balasubramanian S, Phan AT. Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter. Nucleic Acids Research. PMID 30551210 DOI: 10.1093/Nar/Gky1179 |
0.538 |
|
| 2018 |
Raiber EA, Portella G, Martínez Cuesta S, Hardisty R, Murat P, Li Z, Iurlaro M, Dean W, Spindel J, Beraldi D, Liu Z, Dawson MA, Reik W, Balasubramanian S. 5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells. Nature Chemistry. PMID 30349137 DOI: 10.1038/S41557-018-0149-X |
0.806 |
|
| 2018 |
Mao SQ, Ghanbarian AT, Spiegel J, Martínez Cuesta S, Beraldi D, Di Antonio M, Marsico G, Hänsel-Hertsch R, Tannahill D, Balasubramanian S. DNA G-quadruplex structures mold the DNA methylome. Nature Structural & Molecular Biology. PMID 30275516 DOI: 10.1038/S41594-018-0131-8 |
0.839 |
|
| 2018 |
Herdy B, Mayer C, Varshney D, Marsico G, Murat P, Taylor C, D'Santos C, Tannahill D, Balasubramanian S. Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts. Nucleic Acids Research. PMID 30256975 DOI: 10.1093/Nar/Gky861 |
0.815 |
|
| 2018 |
Kwok CK, Marsico G, Balasubramanian S. Detecting RNA G-Quadruplexes (rG4s) in the Transcriptome. Cold Spring Harbor Perspectives in Biology. 10. PMID 29967010 DOI: 10.1101/Cshperspect.A032284 |
0.77 |
|
| 2018 |
Chen MC, Tippana R, Demeshkina NA, Murat P, Balasubramanian S, Myong S, Ferré-D'Amaré AR. Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature. PMID 29899445 DOI: 10.1038/S41586-018-0209-9 |
0.729 |
|
| 2018 |
Kawasaki F, Martínez Cuesta S, Beraldi D, Mahtey A, Hardisty RE, Carrington M, Balasubramanian S. Sequencing 5-hydroxymethyluracil at single-base resolution. Angewandte Chemie (International Ed. in English). PMID 29882366 DOI: 10.1002/Anie.201804046 |
0.795 |
|
| 2018 |
Parry AJ, Hoare M, Bihary D, Hänsel-Hertsch R, Smith S, Tomimatsu K, Mannion E, Smith A, D'Santos P, Russell IA, Balasubramanian S, Kimura H, Samarajiwa SA, Narita M. NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence. Nature Communications. 9: 1840. PMID 29743479 DOI: 10.1038/S41467-018-04283-9 |
0.772 |
|
| 2018 |
Hänsel-Hertsch R, Spiegel J, Marsico G, Tannahill D, Balasubramanian S. Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing. Nature Protocols. 13: 551-564. PMID 29470465 DOI: 10.1038/Nprot.2017.150 |
0.852 |
|
| 2018 |
Marchetti C, Zyner KG, Ohnmacht SA, Robson M, Haider SM, Morton JP, Marsico G, Vo T, Laughlin-Toth S, Ahmed AA, Di Vita G, Pazitna I, Gunaratnam M, Besser RJ, Andrade AC, ... ... Balasubramanian S, et al. Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule. Journal of Medicinal Chemistry. PMID 29356532 DOI: 10.1021/Acs.Jmedchem.7B01781 |
0.805 |
|
| 2017 |
Raiber EA, Beraldi D, Martínez Cuesta S, McInroy GR, Kingsbury Z, Becq J, James T, Lopes M, Allinson K, Field S, Humphray S, Santarius T, Watts C, Bentley D, Balasubramanian S. Base resolution maps reveal the importance of 5-hydroxymethylcytosine in a human glioblastoma. Npj Genomic Medicine. 2: 6. PMID 29263824 DOI: 10.1038/S41525-017-0007-6 |
0.787 |
|
| 2017 |
Sahakyan AB, Chambers VS, Marsico G, Santner T, Di Antonio M, Balasubramanian S. Machine learning model for sequence-driven DNA G-quadruplex formation. Scientific Reports. 7: 14535. PMID 29109402 DOI: 10.1038/S41598-017-14017-4 |
0.837 |
|
| 2017 |
Guilbaud G, Murat P, Recolin B, Campbell BC, Maiter A, Sale JE, Balasubramanian S. Local epigenetic reprogramming induced by G-quadruplex ligands. Nature Chemistry. 9: 1110-1117. PMID 29064488 DOI: 10.1038/Nchem.2828 |
0.691 |
|
| 2017 |
Shendure J, Balasubramanian S, Church GM, Gilbert W, Rogers J, Schloss JA, Waterston RH. DNA sequencing at 40: past, present and future. Nature. PMID 29019985 DOI: 10.1038/Nature24286 |
0.404 |
|
| 2017 |
Balasubramanian S, Tanpure AA. Synthesis and multiple incorporations of 2'-O-methyl-5-hydroxymethyl-, 5-hydroxymethyl- and 5-formylcytidine monomers into RNA oligonucleotides. Chembiochem : a European Journal of Chemical Biology. PMID 28901692 DOI: 10.1002/Cbic.201700492 |
0.318 |
|
| 2017 |
van Delft P, Akay A, Huber SM, Bueschl C, Rudolph KLM, Di Domenico T, Schuhmacher R, Miska EA, Balasubramanian S. The Profile and Dynamics of RNA Modifications in Animals. Chembiochem : a European Journal of Chemical Biology. PMID 28449301 DOI: 10.1002/Cbic.201700093 |
0.303 |
|
| 2017 |
Hänsel-Hertsch R, Antonio MD, Balasubramanian S. DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential. Nature Reviews. Molecular Cell Biology. PMID 28225080 DOI: 10.1038/Nrm.2017.3 |
0.847 |
|
| 2017 |
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, ... ... Balasubramanian S, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nature Communications. 8: 14432. PMID 28211448 DOI: 10.1038/Ncomms14432 |
0.474 |
|
| 2017 |
Milagre I, Stubbs TM, King MR, Spindel J, Santos F, Krueger F, Bachman M, Segonds-Pichon A, Balasubramanian S, Andrews SR, Dean W, Reik W. Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming. Cell Reports. 18: 1079-1089. PMID 28147265 DOI: 10.1016/J.Celrep.2017.01.008 |
0.373 |
|
| 2017 |
Kawasaki F, Beraldi D, Hardisty RE, McInroy GR, van Delft P, Balasubramanian S. Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania. Genome Biology. 18: 23. PMID 28137275 DOI: 10.1186/S13059-017-1150-1 |
0.754 |
|
| 2017 |
Sahakyan AB, Murat P, Mayer C, Balasubramanian S. G-quadruplex structures within the 3' UTR of LINE-1 elements stimulate retrotransposition. Nature Structural & Molecular Biology. PMID 28134931 DOI: 10.1038/Nsmb.3367 |
0.814 |
|
| 2017 |
Huber SM, van Delft P, Tanpure AA, Miska EA, Balasubramanian S. 2'-O-methyl-5-hydroxymethylcytidine - a second oxidative derivative of 5-methylcytidine in RNA. Journal of the American Chemical Society. PMID 28107630 DOI: 10.1021/Jacs.6B12180 |
0.303 |
|
| 2017 |
Sahakyan AB, Balasubramanian S. Single genome retrieval of context-dependent variability in mutation rates for human germline. Bmc Genomics. 18: 81. PMID 28086752 DOI: 10.1186/S12864-016-3440-5 |
0.676 |
|
| 2017 |
Kawasaki F, Murat P, Li Z, Santner T, Balasubramanian S. Synthesis and biophysical analysis of modified thymine-containing DNA oligonucleotides. Chemical Communications (Cambridge, England). PMID 28074944 DOI: 10.1039/C6Cc08670E |
0.815 |
|
| 2017 |
Balasubramanian S. Abstract PL04-01: G-quadruplexes and DNA dynamics Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Pl04-01 |
0.463 |
|
| 2017 |
Raiber E, Beraldi D, Cuesta SM, McInroy G, Kingsbury Z, Becq J, James T, Lopes M, Allinson K, Field S, Humphray S, Santarius T, Watts C, Bentley D, Balasubramanian S. GENE-46. COMPARISON OF MATCHED GLIOBLASTOMA TUMOR AND MARGIN SAMPLES USING SINGLE BASE RESOLUTION MAPS REVEALS ACQUIRED, EARLY EPIGENETIC CHANGES THAT PREDISPOSE TO MUTATIONS DURING TUMOURIGENESIS Neuro-Oncology. 19: vi102-vi102. DOI: 10.1093/Neuonc/Nox168.419 |
0.766 |
|
| 2016 |
Lightfoot HL, Miska EA, Balasubramanian S. Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing. Organic & Biomolecular Chemistry. PMID 27731469 DOI: 10.1039/C6Ob01945E |
0.328 |
|
| 2016 |
Hänsel-Hertsch R, Beraldi D, Lensing SV, Marsico G, Zyner K, Parry A, Di Antonio M, Pike J, Kimura H, Narita M, Tannahill D, Balasubramanian S. G-quadruplex structures mark human regulatory chromatin. Nature Genetics. PMID 27618450 DOI: 10.1038/Ng.3662 |
0.834 |
|
| 2016 |
Kwok CK, Marsico G, Sahakyan AB, Chambers VS, Balasubramanian S. rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome. Nature Methods. PMID 27571552 DOI: 10.1038/Nmeth.3965 |
0.819 |
|
| 2016 |
Lensing SV, Marsico G, Hänsel-Hertsch R, Lam EY, Tannahill D, Balasubramanian S. DSBCapture: in situ capture and sequencing of DNA breaks. Nature Methods. PMID 27525976 DOI: 10.1038/Nmeth.3960 |
0.813 |
|
| 2016 |
Mayer C, McInroy GR, Murat P, Van Delft P, Balasubramanian S. An Epigenetics-Inspired DNA-Based Data Storage System. Angewandte Chemie (International Ed. in English). PMID 27440712 DOI: 10.1002/Anie.201605531 |
0.711 |
|
| 2016 |
Iurlaro M, McInroy GR, Burgess HE, Dean W, Raiber EA, Bachman M, Beraldi D, Balasubramanian S, Reik W. In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine. Genome Biology. 17: 141. PMID 27356509 DOI: 10.1186/S13059-016-1001-5 |
0.801 |
|
| 2016 |
Kwok CK, Sahakyan AB, Balasubramanian S. Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA. Angewandte Chemie (International Ed. in English). PMID 27355429 DOI: 10.1002/Anie.201603562 |
0.8 |
|
| 2016 |
Adam J, Adamová D, Aggarwal MM, Aglieri Rinella G, Agnello M, Agrawal N, Ahammed Z, Ahmad S, Ahn SU, Aiola S, Akindinov A, Alam SN, Aleksandrov D, Alessandro B, Alexandre D, ... ... Balasubramanian S, et al. Centrality Dependence of the Charged-Particle Multiplicity Density at Midrapidity in Pb-Pb Collisions at sqrt[s_{NN}]=5.02 TeV. Physical Review Letters. 116: 222302. PMID 27314715 DOI: 10.1103/Physrevlett.116.222302 |
0.424 |
|
| 2016 |
Adam J, Adamová D, Aggarwal MM, Aglieri Rinella G, Agnello M, Agrawal N, Ahammed Z, Ahmad S, Ahn SU, Aiola S, Akindinov A, Alam SN, Aleksandrov D, Alessandro B, Alexandre D, ... ... Balasubramanian S, et al. Production of K[Formula: see text](892)[Formula: see text] and [Formula: see text](1020) in p-Pb collisions at [Formula: see text] = 5.02 TeV. The European Physical Journal. C, Particles and Fields. 76: 245. PMID 27217821 DOI: 10.1140/Epjc/S10052-016-4088-7 |
0.425 |
|
| 2016 |
Adam J, Adamová D, Aggarwal MM, Aglieri Rinella G, Agnello M, Agrawal N, Ahammed Z, Ahmad S, Ahn SU, Aiola S, Akindinov A, Alam SN, Albuquerque DS, Aleksandrov D, Alessandro B, ... ... Balasubramanian S, et al. Anisotropic Flow of Charged Particles in Pb-Pb Collisions at sqrt[s_{NN}]=5.02 TeV. Physical Review Letters. 116: 132302. PMID 27081971 DOI: 10.1103/Physrevlett.116.132302 |
0.421 |
|
| 2016 |
McInroy GR, Beraldi D, Raiber EA, Modrzynska K, van Delft P, Billker O, Balasubramanian S. Enhanced Methylation Analysis by Recovery of Unsequenceable Fragments. Plos One. 11: e0152322. PMID 27031619 DOI: 10.1371/Journal.Pone.0152322 |
0.816 |
|
| 2016 |
Sahakyan AB, Balasubramanian S. Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases. Bmc Genomics. 17: 225. PMID 26968808 DOI: 10.1186/S12864-016-2582-9 |
0.667 |
|
| 2016 |
Cording A, Gormally M, Bond PJ, Carrington M, Balasubramanian S, Miska EA, Thomas B. Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications. Rna Biology. 0. PMID 26786754 DOI: 10.1080/15476286.2015.1137422 |
0.321 |
|
| 2016 |
Walker OS, Elsässer SJ, Mahesh M, Bachman M, Balasubramanian S, Chin JW. Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes. Journal of the American Chemical Society. PMID 26761588 DOI: 10.1021/Jacs.5B07627 |
0.339 |
|
| 2016 |
Gormally M, Marsico G, Rai G, Lowe C, Thomas C, Maloney D, Michael S, Matak-Vincovic D, Jadhav A, Simeonov A, Balasubramanian S. Abstract 3088: Transcription factor as target: Novel small molecule inhibits FOXM1 DNA binding and oncogenic gene products Cancer Research. 76: 3088-3088. DOI: 10.1158/1538-7445.Am2016-3088 |
0.403 |
|
| 2016 |
Lensing S, Marsico G, Hänsel-Hertsch R, Lam E, Tannahill D, Balasubramanian S. DSBCapture: in situ single-nucleotide resolution DNA double-strand break mapping Protocol Exchange. DOI: 10.1038/Protex.2016.52 |
0.797 |
|
| 2016 |
Kwok CK, Marsico G, Sahakyan AB, Chambers VS, Balasubramanian S. Transcriptome-wide profiling of RNA G-quadruplex structures using rG4-seq Protocol Exchange. DOI: 10.1038/Protex.2016.060 |
0.821 |
|
| 2015 |
Patalano S, Vlasova A, Wyatt C, Ewels P, Camara F, Ferreira PG, Asher CL, Jurkowski TP, Segonds-Pichon A, Bachman M, González-Navarrete I, Minoche AE, Krueger F, Lowy E, Marcet-Houben M, ... ... Balasubramanian S, et al. Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies. Proceedings of the National Academy of Sciences of the United States of America. 112: 13970-5. PMID 26483466 DOI: 10.1073/Pnas.1515937112 |
0.311 |
|
| 2015 |
Yangyuoru PM, Di Antonio M, Ghimire C, Biffi G, Balasubramanian S, Mao H. Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 127: 924-927. PMID 26300569 DOI: 10.1002/Ange.201408113 |
0.696 |
|
| 2015 |
Chambers VS, Marsico G, Boutell JM, Di Antonio M, Smith GP, Balasubramanian S. High-throughput sequencing of DNA G-quadruplex structures in the human genome. Nature Biotechnology. PMID 26192317 DOI: 10.1038/Nbt.3295 |
0.725 |
|
| 2015 |
Sanders DA, Gormally MV, Marsico G, Beraldi D, Tannahill D, Balasubramanian S. FOXM1 binds directly to non-consensus sequences in the human genome. Genome Biology. 16: 130. PMID 26100407 DOI: 10.1186/S13059-015-0696-Z |
0.818 |
|
| 2015 |
Bachman M, Uribe-Lewis S, Yang X, Burgess HE, Iurlaro M, Reik W, Murrell A, Balasubramanian S. 5-Formylcytosine can be a stable DNA modification in mammals. Nature Chemical Biology. PMID 26098680 DOI: 10.1038/Nchembio.1848 |
0.406 |
|
| 2015 |
Hardisty RE, Kawasaki F, Sahakyan AB, Balasubramanian S. Selective Chemical Labeling of Natural T Modifications in DNA. Journal of the American Chemical Society. PMID 25946119 DOI: 10.1021/Jacs.5B03730 |
0.793 |
|
| 2015 |
Kwok CK, Balasubramanian S. Targeted Detection of G-Quadruplexes in Cellular RNAs. Angewandte Chemie (International Ed. in English). 54: 6751-4. PMID 25907625 DOI: 10.1002/Anie.201500891 |
0.698 |
|
| 2015 |
Le DD, Di Antonio M, Chan LK, Balasubramanian S. G-quadruplex ligands exhibit differential G-tetrad selectivity. Chemical Communications (Cambridge, England). 51: 8048-50. PMID 25864836 DOI: 10.1039/C5Cc02252E |
0.683 |
|
| 2015 |
Field SF, Beraldi D, Bachman M, Stewart SK, Beck S, Balasubramanian S. Accurate measurement of 5-methylcytosine and 5-hydroxymethylcytosine in human cerebellum DNA by oxidative bisulfite on an array (OxBS-array). Plos One. 10: e0118202. PMID 25706862 DOI: 10.1371/Journal.Pone.0118202 |
0.739 |
|
| 2015 |
Huber SM, van Delft P, Mendil L, Bachman M, Smollett K, Werner F, Miska EA, Balasubramanian S. Formation and abundance of 5-hydroxymethylcytosine in RNA. Chembiochem : a European Journal of Chemical Biology. 16: 752-5. PMID 25676849 DOI: 10.1002/Cbic.201500013 |
0.305 |
|
| 2015 |
Chen MC, Murat P, Abecassis K, Ferré-D'Amaré AR, Balasubramanian S. Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase. Nucleic Acids Research. 43: 2223-31. PMID 25653156 DOI: 10.1093/Nar/Gkv051 |
0.7 |
|
| 2015 |
Raiber EA, Murat P, Chirgadze DY, Beraldi D, Luisi BF, Balasubramanian S. 5-Formylcytosine alters the structure of the DNA double helix. Nature Structural & Molecular Biology. 22: 44-9. PMID 25504322 DOI: 10.1038/Nsmb.2936 |
0.827 |
|
| 2015 |
Yangyuoru PM, Di Antonio M, Ghimire C, Biffi G, Balasubramanian S, Mao H. Dual binding of an antibody and a small molecule increases the stability of TERRA G-quadruplex. Angewandte Chemie (International Ed. in English). 54: 910-3. PMID 25421962 DOI: 10.1002/anie.201408113 |
0.668 |
|
| 2015 |
Balasubramanian S. Solexa sequencing: decoding genomes on a population scale. Clinical Chemistry. 61: 21-4. PMID 25332311 DOI: 10.1373/Clinchem.2014.221747 |
0.394 |
|
| 2015 |
Booth MJ, Raiber EA, Balasubramanian S. Chemical methods for decoding cytosine modifications in DNA. Chemical Reviews. 115: 2240-54. PMID 25094039 DOI: 10.1021/Cr5002904 |
0.79 |
|
| 2015 |
Kendrick SL, Tannahill D, Balasubramanian S, Rimsza LM. Concurrent BCL2 / MYC Gene Amplification Associates with Increased DNA G-Quadruplex Formation in DLBCL Blood. 126: 2641-2641. DOI: 10.1182/Blood.V126.23.2641.2641 |
0.717 |
|
| 2015 |
McInroy GR, Bell NM, Ficz G, Balasubramanian S, Reik W, Raiber EA. The biology and genomic localization of cytosine modifications Epigenetics and Human Health. 4: 167-191. DOI: 10.1007/978-3-642-31974-7_8 |
0.709 |
|
| 2014 |
Bachman M, Uribe-Lewis S, Yang X, Williams M, Murrell A, Balasubramanian S. 5-Hydroxymethylcytosine is a predominantly stable DNA modification. Nature Chemistry. 6: 1049-55. PMID 25411882 DOI: 10.1038/Nchem.2064 |
0.41 |
|
| 2014 |
Gormally MV, Dexheimer TS, Marsico G, Sanders DA, Lowe C, Matak-Vinkovi? D, Michael S, Jadhav A, Rai G, Maloney DJ, Simeonov A, Balasubramanian S. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nature Communications. 5: 5165. PMID 25387393 DOI: 10.1038/Ncomms6165 |
0.664 |
|
| 2014 |
Müller S, Laxmi-Reddy K, Jena PV, Baptiste B, Dong Z, Godde F, Ha T, Rodriguez R, Balasubramanian S, Huc I. Targeting DNA G-quadruplexes with helical small molecules. Chembiochem : a European Journal of Chemical Biology. 15: 2563-70. PMID 25256604 DOI: 10.1002/Cbic.201402439 |
0.518 |
|
| 2014 |
Schiavone D, Guilbaud G, Murat P, Papadopoulou C, Sarkies P, Prioleau MN, Balasubramanian S, Sale JE. Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells. The Embo Journal. 33: 2507-20. PMID 25190518 DOI: 10.15252/Embj.201488398 |
0.689 |
|
| 2014 |
McInroy GR, Raiber EA, Balasubramanian S. Chemical biology of genomic DNA: minimizing PCR bias. Chemical Communications (Cambridge, England). 50: 12047-9. PMID 25178041 DOI: 10.1039/C4Cc05107F |
0.771 |
|
| 2014 |
Wang I, Kowalski MP, Langley AR, Rodriguez R, Balasubramanian S, Hsu ST, Krude T. Nucleotide contributions to the structural integrity and DNA replication initiation activity of noncoding y RNA. Biochemistry. 53: 5848-63. PMID 25151917 DOI: 10.1021/Bi500470B |
0.432 |
|
| 2014 |
Biffi G, Tannahill D, Miller J, Howat WJ, Balasubramanian S. Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues. Plos One. 9: e102711. PMID 25033211 DOI: 10.1371/Journal.Pone.0102711 |
0.81 |
|
| 2014 |
Balasubramanian S. Chemical biology on the genome. Bioorganic & Medicinal Chemistry. 22: 4356-70. PMID 24957879 DOI: 10.1016/J.Bmc.2014.05.016 |
0.457 |
|
| 2014 |
Booth MJ, Marsico G, Bachman M, Beraldi D, Balasubramanian S. Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution. Nature Chemistry. 6: 435-40. PMID 24755596 DOI: 10.1038/Nchem.1893 |
0.792 |
|
| 2014 |
Di Antonio M, McLuckie KI, Balasubramanian S. Reprogramming the mechanism of action of chlorambucil by coupling to a G-quadruplex ligand. Journal of the American Chemical Society. 136: 5860-3. PMID 24697838 DOI: 10.1021/Ja5014344 |
0.453 |
|
| 2014 |
Murat P, Zhong J, Lekieffre L, Cowieson NP, Clancy JL, Preiss T, Balasubramanian S, Khanna R, Tellam J. G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation. Nature Chemical Biology. 10: 358-64. PMID 24633353 DOI: 10.1038/Nchembio.1479 |
0.627 |
|
| 2014 |
Murat P, Balasubramanian S. Existence and consequences of G-quadruplex structures in DNA. Current Opinion in Genetics & Development. 25: 22-9. PMID 24584093 DOI: 10.1016/J.Gde.2013.10.012 |
0.693 |
|
| 2014 |
Nasiri HR, Bell NM, McLuckie KI, Husby J, Abell C, Neidle S, Balasubramanian S. Targeting a c-MYC G-quadruplex DNA with a fragment library. Chemical Communications (Cambridge, England). 50: 1704-7. PMID 24394582 DOI: 10.1039/C3Cc48390H |
0.591 |
|
| 2014 |
Biffi G, Di Antonio M, Tannahill D, Balasubramanian S. Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nature Chemistry. 6: 75-80. PMID 24345950 DOI: 10.1038/Nchem.1805 |
0.826 |
|
| 2014 |
Booth MJ, Marsico G, Bachman M, Beraldi D, Balasubramanian S. Addendum: Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution Nature Chemistry. 6: 553-553. DOI: 10.1038/Nchem.1959 |
0.782 |
|
| 2013 |
Bell NM, L'Hernault A, Murat P, Richards JE, Lever AM, Balasubramanian S. Targeting RNA-protein interactions within the human immunodeficiency virus type 1 lifecycle. Biochemistry. 52: 9269-74. PMID 24358934 DOI: 10.1021/Bi401270D |
0.593 |
|
| 2013 |
Wu L, Murat P, Matak-Vinkovic D, Murrell A, Balasubramanian S. Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins. Biochemistry. 52: 9519-27. PMID 24320048 DOI: 10.1021/Bi401085H |
0.604 |
|
| 2013 |
Iurlaro M, Ficz G, Oxley D, Raiber EA, Bachman M, Booth MJ, Andrews S, Balasubramanian S, Reik W. A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biology. 14: R119. PMID 24156278 DOI: 10.1186/Gb-2013-14-10-R119 |
0.778 |
|
| 2013 |
Yangyuoru PM, Zhang AY, Shi Z, Koirala D, Balasubramanian S, Mao H. Mechanochemical properties of individual human telomeric RNA (TERRA) G-quadruplexes. Chembiochem : a European Journal of Chemical Biology. 14: 1931-5. PMID 24038851 DOI: 10.1002/Cbic.201300350 |
0.427 |
|
| 2013 |
Booth MJ, Ost TW, Beraldi D, Bell NM, Branco MR, Reik W, Balasubramanian S. Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine. Nature Protocols. 8: 1841-51. PMID 24008380 DOI: 10.1038/Nprot.2013.115 |
0.691 |
|
| 2013 |
Murat P, Gormally MV, Sanders D, Di Antonio M, Balasubramanian S. Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand. Chemical Communications (Cambridge, England). 49: 8453-5. PMID 23949446 DOI: 10.1039/C3Cc44737E |
0.618 |
|
| 2013 |
McLuckie KI, Di Antonio M, Zecchini H, Xian J, Caldas C, Krippendorff BF, Tannahill D, Lowe C, Balasubramanian S. G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells. Journal of the American Chemical Society. 135: 9640-3. PMID 23782415 DOI: 10.1021/Ja404868T |
0.718 |
|
| 2013 |
Lam EY, Beraldi D, Tannahill D, Balasubramanian S. G-quadruplex structures are stable and detectable in human genomic DNA. Nature Communications. 4: 1796. PMID 23653208 DOI: 10.1038/Ncomms2792 |
0.86 |
|
| 2013 |
Biffi G, Tannahill D, McCafferty J, Balasubramanian S. Quantitative visualization of DNA G-quadruplex structures in human cells. Nature Chemistry. 5: 182-6. PMID 23422559 DOI: 10.1038/Nchem.1548 |
0.83 |
|
| 2013 |
Mitchell T, Ramos-Montoya A, Di Antonio M, Murat P, Ohnmacht S, Micco M, Jurmeister S, Fryer L, Balasubramanian S, Neidle S, Neal DE. Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer. Biochemistry. 52: 1429-36. PMID 23363071 DOI: 10.1021/Bi301349C |
0.654 |
|
| 2013 |
Sanders DA, Ross-Innes CS, Beraldi D, Carroll JS, Balasubramanian S. Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells. Genome Biology. 14: R6. PMID 23347430 DOI: 10.1186/Gb-2013-14-1-R6 |
0.672 |
|
| 2013 |
Nikan M, Di Antonio M, Abecassis K, McLuckie K, Balasubramanian S. An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel G-quadruplexes. Angewandte Chemie (International Ed. in English). 52: 1428-31. PMID 23238938 DOI: 10.1002/Anie.201207075 |
0.81 |
|
| 2013 |
Mitchell T, Ramos-Montoya A, Di Antonio M, Murat P, Ohnmacht S, Micco M, Fryer L, Balasubramanian S, Neidle S, Neal D. 823 Transcriptional down-regulation of the androgen receptor by promoter G-quadruplex stabilisation; a potential alternative treatment in castrate-resistant prostate cancer European Urology Supplements. 12: e823-e824. DOI: 10.1016/S1569-9056(13)61303-2 |
0.587 |
|
| 2012 |
Bugaut A, Murat P, Balasubramanian S. An RNA hairpin to G-quadruplex conformational transition. Journal of the American Chemical Society. 134: 19953-6. PMID 23190255 DOI: 10.1021/Ja308665G |
0.659 |
|
| 2012 |
Zhang AY, Balasubramanian S. The kinetics and folding pathways of intramolecular G-quadruplex nucleic acids. Journal of the American Chemical Society. 134: 19297-308. PMID 23113843 DOI: 10.1021/Ja309851T |
0.496 |
|
| 2012 |
Di Antonio M, Biffi G, Mariani A, Raiber EA, Rodriguez R, Balasubramanian S. Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry. Angewandte Chemie (International Ed. in English). 51: 11073-8. PMID 23038154 DOI: 10.1002/Anie.201206281 |
0.829 |
|
| 2012 |
Raiber EA, Beraldi D, Ficz G, Burgess HE, Branco MR, Murat P, Oxley D, Booth MJ, Reik W, Balasubramanian S. Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biology. 13: R69. PMID 22902005 DOI: 10.1186/Gb-2012-13-8-R69 |
0.814 |
|
| 2012 |
Müller S, Sanders DA, Di Antonio M, Matsis S, Riou JF, Rodriguez R, Balasubramanian S. Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. Organic & Biomolecular Chemistry. 10: 6537-46. PMID 22790277 DOI: 10.1039/C2Ob25830G |
0.48 |
|
| 2012 |
Biffi G, Tannahill D, Balasubramanian S. An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2. Journal of the American Chemical Society. 134: 11974-6. PMID 22780456 DOI: 10.1021/Ja305734X |
0.818 |
|
| 2012 |
Booth MJ, Branco MR, Ficz G, Oxley D, Krueger F, Reik W, Balasubramanian S. Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science (New York, N.Y.). 336: 934-7. PMID 22539555 DOI: 10.1126/Science.1220671 |
0.423 |
|
| 2012 |
Bell NM, Kenyon JC, Balasubramanian S, Lever AM. Comparative structural effects of HIV-1 Gag and nucleocapsid proteins in binding to and unwinding of the viral RNA packaging signal. Biochemistry. 51: 3162-9. PMID 22448757 DOI: 10.1021/Bi2017969 |
0.337 |
|
| 2012 |
Bugaut A, Balasubramanian S. 5'-UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Research. 40: 4727-41. PMID 22351747 DOI: 10.1093/Nar/Gks068 |
0.471 |
|
| 2012 |
Di Antonio M, Rodriguez R, Balasubramanian S. Experimental approaches to identify cellular G-quadruplex structures and functions. Methods (San Diego, Calif.). 57: 84-92. PMID 22343041 DOI: 10.1016/J.Ymeth.2012.01.008 |
0.554 |
|
| 2012 |
Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nature Chemical Biology. 8: 301-10. PMID 22306580 DOI: 10.1038/Nchembio.780 |
0.788 |
|
| 2012 |
Mela I, Kranaster R, Henderson RM, Balasubramanian S, Edwardson JM. Demonstration of ligand decoration, and ligand-induced perturbation, of G-quadruplexes in a plasmid using atomic force microscopy. Biochemistry. 51: 578-85. PMID 22225525 DOI: 10.1021/Bi201600G |
0.823 |
|
| 2012 |
Dash J, Das RN, Hegde N, PantoÅŸ GD, Shirude PS, Balasubramanian S. Synthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 554-64. PMID 22161991 DOI: 10.1002/Chem.201102556 |
0.754 |
|
| 2012 |
Sarkies P, Murat P, Phillips LG, Patel KJ, Balasubramanian S, Sale JE. FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Research. 40: 1485-98. PMID 22021381 DOI: 10.1093/Nar/Gkr868 |
0.714 |
|
| 2012 |
Raiber EA, Kranaster R, Lam E, Nikan M, Balasubramanian S. A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro. Nucleic Acids Research. 40: 1499-508. PMID 22021377 DOI: 10.1093/Nar/Gkr882 |
0.815 |
|
| 2012 |
Di Antonio M, Biffi G, Mariani A, Raiber E, Rodriguez R, Balasubramanian S. Inside Cover: Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry (Angew. Chem. Int. Ed. 44/2012) Angewandte Chemie International Edition. 51: 10906-10906. DOI: 10.1002/Anie.201207794 |
0.836 |
|
| 2012 |
Di Antonio M, Biffi G, Mariani A, Raiber E, Rodriguez R, Balasubramanian S. Innentitelbild: Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry (Angew. Chem. 44/2012) Angewandte Chemie. 124: 11064-11064. DOI: 10.1002/Ange.201207794 |
0.837 |
|
| 2011 |
Balasubramanian S. Decoding genomes at high speed: implications for science and medicine. Angewandte Chemie (International Ed. in English). 50: 12406-10. PMID 22144295 DOI: 10.1002/Anie.201106707 |
0.311 |
|
| 2011 |
Koirala D, Dhakal S, Ashbridge B, Sannohe Y, Rodriguez R, Sugiyama H, Balasubramanian S, Mao H. A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. Nature Chemistry. 3: 782-7. PMID 21941250 DOI: 10.1038/Nchem.1126 |
0.435 |
|
| 2011 |
Hegde NS, Sanders DA, Rodriguez R, Balasubramanian S. The transcription factor FOXM1 is a cellular target of the natural product thiostrepton. Nature Chemistry. 3: 725-31. PMID 21860463 DOI: 10.1038/Nchem.1114 |
0.372 |
|
| 2011 |
Lightfoot HL, Bugaut A, Armisen J, Lehrbach NJ, Miska EA, Balasubramanian S. A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing. Biochemistry. 50: 7514-21. PMID 21815640 DOI: 10.1021/Bi200851D |
0.463 |
|
| 2011 |
Zhang AY, Bugaut A, Balasubramanian S. A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology. Biochemistry. 50: 7251-8. PMID 21744844 DOI: 10.1021/Bi200805J |
0.529 |
|
| 2011 |
Balasubramanian S, Hurley LH, Neidle S. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? Nature Reviews. Drug Discovery. 10: 261-75. PMID 21455236 DOI: 10.1038/Nrd3428 |
0.466 |
|
| 2011 |
Smith JS, Chen Q, Yatsunyk LA, Nicoludis JM, Garcia MS, Kranaster R, Balasubramanian S, Monchaud D, Teulade-Fichou MP, Abramowitz L, Schultz DC, Johnson FB. Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae. Nature Structural & Molecular Biology. 18: 478-85. PMID 21399640 DOI: 10.1038/Nsmb.2033 |
0.827 |
|
| 2011 |
Dash J, Waller ZA, Panto? GD, Balasubramanian S. Synthesis and binding studies of novel diethynyl-pyridine amides with genomic promoter DNA G-quadruplexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 4571-81. PMID 21387430 DOI: 10.1002/Chem.201003157 |
0.848 |
|
| 2011 |
McLuckie KI, Waller ZA, Sanders DA, Alves D, Rodriguez R, Dash J, McKenzie GJ, Venkitaraman AR, Balasubramanian S. G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells. Journal of the American Chemical Society. 133: 2658-63. PMID 21294544 DOI: 10.1021/Ja109474C |
0.845 |
|
| 2010 |
Bejugam M, Gunaratnam M, Müller S, Sanders DA, Sewitz S, Fletcher JA, Neidle S, Balasubramanian S. Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines. Acs Medicinal Chemistry Letters. 1: 306-10. PMID 24900212 DOI: 10.1021/Ml100062Z |
0.439 |
|
| 2010 |
Müller S, Kumari S, Rodriguez R, Balasubramanian S. Small-molecule-mediated G-quadruplex isolation from human cells. Nature Chemistry. 2: 1095-8. PMID 21107376 DOI: 10.1038/Nchem.842 |
0.533 |
|
| 2010 |
Marnef A, Maldonado M, Bugaut A, Balasubramanian S, Kress M, Weil D, Standart N. Distinct functions of maternal and somatic Pat1 protein paralogs. Rna (New York, N.Y.). 16: 2094-107. PMID 20826699 DOI: 10.1261/Rna.2295410 |
0.318 |
|
| 2010 |
Shahid R, Bugaut A, Balasubramanian S. The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression. Biochemistry. 49: 8300-6. PMID 20726580 DOI: 10.1021/Bi100957H |
0.449 |
|
| 2010 |
Bugaut A, Rodriguez R, Kumari S, Hsu ST, Balasubramanian S. Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex. Organic & Biomolecular Chemistry. 8: 2771-6. PMID 20436976 DOI: 10.1039/C002418J |
0.419 |
|
| 2010 |
Yeoman JA, Orte A, Ashbridge B, Klenerman D, Balasubramanian S. RNA conformation in catalytically active human telomerase. Journal of the American Chemical Society. 132: 2852-3. PMID 20148555 DOI: 10.1021/Ja909383N |
0.327 |
|
| 2010 |
Fegan A, Shirude PS, Ying L, Balasubramanian S. Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes. Chemical Communications (Cambridge, England). 46: 946-8. PMID 20107659 DOI: 10.1039/B920680A |
0.393 |
|
| 2010 |
Bejugam M, Gunaratnam M, Müller S, Sanders DA, Sewitz S, Fletcher JA, Neidle S, Balasubramanian S. Correction to Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines Acs Medicinal Chemistry Letters. 1: 546-546. DOI: 10.1021/Ml100241W |
0.357 |
|
| 2009 |
Fernando H, Sewitz S, Darot J, Tavaré S, Huppert JL, Balasubramanian S. Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression. Nucleic Acids Research. 37: 6716-22. PMID 19745055 DOI: 10.1093/Nar/Gkp740 |
0.678 |
|
| 2009 |
Hsu STD, Varnai P, Bugaut A, Reszka AP, Neidle S, Balasubramanian S. A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics Journal of the American Chemical Society. 131: 13399-13409. PMID 19705869 DOI: 10.1021/Ja904007P |
0.451 |
|
| 2009 |
Waller ZA, Sewitz SA, Hsu ST, Balasubramanian S. A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression. Journal of the American Chemical Society. 131: 12628-33. PMID 19689109 DOI: 10.1021/Ja901892U |
0.839 |
|
| 2009 |
Jena PV, Shirude PS, Okumus B, Laxmi-Reddy K, Godde F, Huc I, Balasubramanian S, Ha T. G-quadruplex DNA bound by a synthetic ligand is highly dynamic. Journal of the American Chemical Society. 131: 12522-3. PMID 19685880 DOI: 10.1021/Ja903408R |
0.466 |
|
| 2009 |
Balasubramanian S, Neidle S. G-quadruplex nucleic acids as therapeutic targets Current Opinion in Chemical Biology. 13: 345-353. PMID 19515602 DOI: 10.1016/J.Cbpa.2009.04.637 |
0.473 |
|
| 2009 |
Müller S, Panto? GD, Rodriguez R, Balasubramanian S. Controlled-folding of a small molecule modulates DNA G-quadruplex recognition. Chemical Communications (Cambridge, England). 80-2. PMID 19082005 DOI: 10.1039/B816861J |
0.46 |
|
| 2009 |
Redman JE, Granadino-Roldán JM, Schouten JA, Ladame S, Reszka AP, Neidle S, Balasubramanian S. Recognition and discrimination of DNA quadruplexes by acridine-peptide conjugates. Organic & Biomolecular Chemistry. 7: 76-84. PMID 19081949 DOI: 10.1039/B814682A |
0.736 |
|
| 2008 |
Kumari S, Bugaut A, Balasubramanian S. Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene. Biochemistry. 47: 12664-9. PMID 18991403 DOI: 10.1021/Bi8010797 |
0.462 |
|
| 2008 |
Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, Hall KP, Evers DJ, Barnes CL, Bignell HR, Boutell JM, Bryant J, Carter RJ, Keira Cheetham R, Cox AJ, et al. Accurate whole human genome sequencing using reversible terminator chemistry. Nature. 456: 53-9. PMID 18987734 DOI: 10.1038/Nature07517 |
0.638 |
|
| 2008 |
Dash J, Shirude PS, Hsu ST, Balasubramanian S. Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes. Journal of the American Chemical Society. 130: 15950-6. PMID 18980309 DOI: 10.1021/Ja8046552 |
0.659 |
|
| 2008 |
London TB, Barber LJ, Mosedale G, Kelly GP, Balasubramanian S, Hickson ID, Boulton SJ, Hiom K. FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. The Journal of Biological Chemistry. 283: 36132-9. PMID 18978354 DOI: 10.1074/Jbc.M808152200 |
0.534 |
|
| 2008 |
Rodriguez R, Müller S, Yeoman JA, Trentesaux C, Riou JF, Balasubramanian S. A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres. Journal of the American Chemical Society. 130: 15758-9. PMID 18975896 DOI: 10.1021/Ja805615W |
0.465 |
|
| 2008 |
Huppert JL, Bugaut A, Kumari S, Balasubramanian S. G-quadruplexes: the beginning and end of UTRs. Nucleic Acids Research. 36: 6260-8. PMID 18832370 DOI: 10.1093/Nar/Gkn511 |
0.485 |
|
| 2008 |
Fernando H, Rodriguez R, Balasubramanian S. Selective recognition of a DNA G-quadruplex by an engineered antibody. Biochemistry. 47: 9365-71. PMID 18702511 DOI: 10.1021/Bi800983U |
0.524 |
|
| 2008 |
Dash J, Shirude PS, Balasubramanian S. G-quadruplex recognition by bis-indole carboxamides. Chemical Communications (Cambridge, England). 3055-7. PMID 18688346 DOI: 10.1039/B806042H |
0.68 |
|
| 2008 |
Shirude PS, Ying L, Balasubramanian S. Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC. Chemical Communications (Cambridge, England). 2007-9. PMID 18536803 DOI: 10.1039/B801465E |
0.439 |
|
| 2008 |
Fegan A, Shirude PS, Balasubramanian S. Rigid cyanine dye nucleic acid labels. Chemical Communications (Cambridge, England). 2004-6. PMID 18536802 DOI: 10.1039/B801629A |
0.356 |
|
| 2008 |
Alves D, Li H, Codrington R, Orte A, Ren X, Klenerman D, Balasubramanian S. Single-molecule analysis of human telomerase monomer. Nature Chemical Biology. 4: 287-9. PMID 18391947 DOI: 10.1038/Nchembio.82 |
0.339 |
|
| 2008 |
Waller ZA, Shirude PS, Rodriguez R, Balasubramanian S. Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition. Chemical Communications (Cambridge, England). 1467-9. PMID 18338058 DOI: 10.1039/B718854D |
0.827 |
|
| 2008 |
Bugaut A, Jantos K, Wietor JL, Rodriguez R, Sanders JK, Balasubramanian S. Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry. Angewandte Chemie (International Ed. in English). 47: 2677-80. PMID 18300215 DOI: 10.1002/Anie.200705589 |
0.373 |
|
| 2008 |
Shirude PS, Balasubramanian S. Single molecule conformational analysis of DNA G-quadruplexes. Biochimie. 90: 1197-206. PMID 18295608 DOI: 10.1016/J.Biochi.2008.01.015 |
0.474 |
|
| 2008 |
Bugaut A, Balasubramanian S. A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. Biochemistry. 47: 689-97. PMID 18092816 DOI: 10.1021/Bi701873C |
0.461 |
|
| 2007 |
Bejugam M, Sewitz S, Shirude PS, Rodriguez R, Shahid R, Balasubramanian S. Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. Journal of the American Chemical Society. 129: 12926-7. PMID 17918848 DOI: 10.1021/Ja075881P |
0.473 |
|
| 2007 |
Shirude PS, Gillies ER, Ladame S, Godde F, Shin-Ya K, Huc I, Balasubramanian S. Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. Journal of the American Chemical Society. 129: 11890-1. PMID 17845042 DOI: 10.1021/Ja073775H |
0.704 |
|
| 2007 |
Rodriguez R, Panto? GD, Gonçalves DP, Sanders JK, Balasubramanian S. Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction. Angewandte Chemie (International Ed. in English). 46: 5405-7. PMID 17562537 DOI: 10.1002/Anie.200605075 |
0.409 |
|
| 2007 |
Shirude PS, Okumus B, Ying L, Ha T, Balasubramanian S. Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. Journal of the American Chemical Society. 129: 7484-5. PMID 17523641 DOI: 10.1021/Ja070497D |
0.467 |
|
| 2007 |
Kumari S, Bugaut A, Huppert JL, Balasubramanian S. An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation. Nature Chemical Biology. 3: 218-21. PMID 17322877 DOI: 10.1038/Nchembio864 |
0.522 |
|
| 2007 |
Huppert JL, Balasubramanian S. G-quadruplexes in promoters throughout the human genome. Nucleic Acids Research. 35: 406-13. PMID 17169996 DOI: 10.1093/Nar/Gkl1057 |
0.488 |
|
| 2006 |
Gonçalves DP, Rodriguez R, Balasubramanian S, Sanders JK. Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands. Chemical Communications (Cambridge, England). 4685-7. PMID 17109036 DOI: 10.1039/B611731G |
0.48 |
|
| 2006 |
Orte A, Clarke R, Balasubramanian S, Klenerman D. Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection. Analytical Chemistry. 78: 7707-15. PMID 17105162 DOI: 10.1021/Ac061122Y |
0.343 |
|
| 2006 |
Redman JE, Ladame S, Reszka AP, Neidle S, Balasubramanian S. Discovery of G-quadruplex stabilizing ligands through direct ELISA of a one-bead-one-compound library. Organic & Biomolecular Chemistry. 4: 4364-9. PMID 17102882 DOI: 10.1039/B611716C |
0.743 |
|
| 2006 |
Gavory G, Symmons MF, Krishnan Ghosh Y, Klenerman D, Balasubramanian S. Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling. Biochemistry. 45: 13304-11. PMID 17073451 DOI: 10.1021/Bi061150A |
0.348 |
|
| 2006 |
Jantos K, Rodriguez R, Ladame S, Shirude PS, Balasubramanian S. Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands. Journal of the American Chemical Society. 128: 13662-3. PMID 17044674 DOI: 10.1021/Ja064713E |
0.706 |
|
| 2006 |
Gonçalves DP, Ladame S, Balasubramanian S, Sanders JK. Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins. Organic & Biomolecular Chemistry. 4: 3337-42. PMID 17036123 DOI: 10.1039/B608494J |
0.721 |
|
| 2006 |
Green JJ, Ladame S, Ying L, Klenerman D, Balasubramanian S. Investigating a quadruplex-ligand interaction by unfolding kinetics. Journal of the American Chemical Society. 128: 9809-12. PMID 16866537 DOI: 10.1021/Ja0615425 |
0.686 |
|
| 2006 |
Fernando H, Reszka AP, Huppert J, Ladame S, Rankin S, Venkitaraman AR, Neidle S, Balasubramanian S. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Biochemistry. 45: 7854-60. PMID 16784237 DOI: 10.1021/Bi0601510 |
0.691 |
|
| 2006 |
Ren X, Li H, Clarke RW, Alves DA, Ying L, Klenerman D, Balasubramanian S. Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy. Journal of the American Chemical Society. 128: 4992-5000. PMID 16608333 DOI: 10.1021/Ja056613Z |
0.349 |
|
| 2006 |
Liu D, Bruckbauer A, Abell C, Balasubramanian S, Kang DJ, Klenerman D, Zhou D. A reversible pH-driven DNA nanoswitch array. Journal of the American Chemical Society. 128: 2067-71. PMID 16464109 DOI: 10.1021/Ja0568300 |
0.64 |
|
| 2006 |
Ladame S, Schouten JA, Roldan J, Redman JE, Neidle S, Balasubramanian S. Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein. Biochemistry. 45: 1393-9. PMID 16445281 DOI: 10.1021/Bi050229X |
0.771 |
|
| 2006 |
Neidle S, Balasubramanian S. Quadruplex nucleic acids. The Royal Society of Chemistry. DOI: 10.1039/9781847555298 |
0.49 |
|
| 2005 |
Shu W, Liu D, Watari M, Riener CK, Strunz T, Welland ME, Balasubramanian S, McKendry RA. DNA molecular motor driven micromechanical cantilever arrays. Journal of the American Chemical Society. 127: 17054-60. PMID 16316252 DOI: 10.1021/Ja0554514 |
0.502 |
|
| 2005 |
Ladame S, Whitney AM, Balasubramanian S. Targeting nucleic acid secondary structures with polyamides using an optimized dynamic combinatorial approach. Angewandte Chemie (International Ed. in English). 44: 5736-9. PMID 16078284 DOI: 10.1002/Anie.200501450 |
0.744 |
|
| 2005 |
Rankin S, Reszka AP, Huppert J, Zloh M, Parkinson GN, Todd AK, Ladame S, Balasubramanian S, Neidle S. Putative DNA quadruplex formation within the human c-kit oncogene. Journal of the American Chemical Society. 127: 10584-9. PMID 16045346 DOI: 10.1021/Ja050823U |
0.703 |
|
| 2005 |
Huppert JL, Balasubramanian S. Prevalence of quadruplexes in the human genome Nucleic Acids Research. 33: 2908-2916. PMID 15914667 DOI: 10.1093/Nar/Gki609 |
0.462 |
|
| 2005 |
Mason SJ, Hake JL, Nairne J, Cummins WJ, Balasubramanian S. Solid-phase methods for the synthesis of cyanine dyes. The Journal of Organic Chemistry. 70: 2939-49. PMID 15822952 DOI: 10.1021/Jo0479415 |
0.561 |
|
| 2004 |
Hazel P, Huppert J, Balasubramanian S, Neidle S. Loop-length-dependent folding of G-quadruplexes Journal of the American Chemical Society. 126: 16405-16415. PMID 15600342 DOI: 10.1021/Ja045154J |
0.395 |
|
| 2004 |
White SS, Ying L, Balasubramanian S, Klenerman D. Individual molecules of dye-labeled DNA act as a reversible two-color switch upon application of an electric field. Angewandte Chemie (International Ed. in English). 43: 5926-30. PMID 15547896 DOI: 10.1002/Anie.200460323 |
0.302 |
|
| 2004 |
Patel SD, Isalan M, Gavory G, Ladame S, Choo Y, Balasubramanian S. Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes. Biochemistry. 43: 13452-8. PMID 15491152 DOI: 10.1021/Bi048892T |
0.726 |
|
| 2004 |
Ladame S, Schouten JA, Stuart J, Roldan J, Neidle S, Balasubramanian S. Tetrapeptides induce selective recognition for G-quadruplexes when conjugated to a DNA-binding platform. Organic & Biomolecular Chemistry. 2: 2925-31. PMID 15480456 DOI: 10.1039/B409698C |
0.749 |
|
| 2004 |
Krishnan-Ghosh Y, Liu D, Balasubramanian S. Formation of an interlocked quadruplex dimer by d(GGGT). Journal of the American Chemical Society. 126: 11009-16. PMID 15339186 DOI: 10.1021/Ja049259Y |
0.482 |
|
| 2004 |
Krishnan-Ghosh Y, Stephens E, Balasubramanian S. A PNA4 quadruplex. Journal of the American Chemical Society. 126: 5944-5945. PMID 15137741 DOI: 10.1021/Ja031508F |
0.411 |
|
| 2004 |
Shammas MA, Liu X, Gavory G, Raney KD, Balasubramanian S, Shmookler Reis RJ. Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells. Experimental Cell Research. 295: 204-14. PMID 15051503 DOI: 10.1016/J.Yexcr.2004.01.003 |
0.669 |
|
| 2004 |
Whitney AM, Ladame S, Balasubramanian S. Templated ligand assembly by using G-quadruplex DNA and dynamic covalent chemistry. Angewandte Chemie (International Ed. in English). 43: 1143-6. PMID 14983458 DOI: 10.1002/Anie.200353069 |
0.694 |
|
| 2004 |
Routledge A, Abell C, Balasubramanian S. An Investigation into Solid-Phase Radical Chemistry - Synthesis of Furan Rings Synlett. 1: 61-62. DOI: 10.1055/S-1997-704 |
0.68 |
|
| 2003 |
Liu D, Balasubramanian S. A proton-fuelled DNA nanomachine. Angewandte Chemie (International Ed. in English). 42: 5734-6. PMID 14661209 DOI: 10.1002/Anie.200352402 |
0.537 |
|
| 2003 |
Ying L, Green JJ, Li H, Klenerman D, Balasubramanian S. Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 100: 14629-34. PMID 14645716 DOI: 10.1073/Pnas.2433350100 |
0.373 |
|
| 2003 |
Schouten JA, Ladame S, Mason SJ, Cooper MA, Balasubramanian S. G-quadruplex-specific peptide-hemicyanine ligands by partial combinatorial selection. Journal of the American Chemical Society. 125: 5594-5. PMID 12733873 DOI: 10.1021/Ja029356W |
0.786 |
|
| 2003 |
Li H, Ying L, Green JJ, Balasubramanian S, Klenerman D. Ultrasensitive coincidence fluorescence detection of single DNA molecules. Analytical Chemistry. 75: 1664-70. PMID 12705600 DOI: 10.1021/Ac026367Z |
0.33 |
|
| 2003 |
Green JJ, Ying L, Klenerman D, Balasubramanian S. Kinetics of unfolding the human telomeric DNA quadruplex using a PNA trap. Journal of the American Chemical Society. 125: 3763-7. PMID 12656607 DOI: 10.1021/Ja029149W |
0.366 |
|
| 2003 |
Whitney A, Gavory G, Balasubramanian S. Site-specific cleavage of human telomerase RNA using PNA-neocuproine·Zn(II) derivatives Chemical Communications. 9: 36-37. DOI: 10.1039/B210135A |
0.321 |
|
| 2002 |
Mason SJ, Balasubramanian S. Solid-phase catch, activate, and release synthesis of cyanine dyes. Organic Letters. 4: 4261-4. PMID 12443073 DOI: 10.1021/Ol026836J |
0.552 |
|
| 2002 |
Gavory G, Farrow M, Balasubramanian S. Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro. Nucleic Acids Research. 30: 4470-80. PMID 12384594 DOI: 10.1093/Nar/Gkf575 |
0.584 |
|
| 2002 |
Horsey I, Krishnan-Ghosh Y, Balasubramanian S. Enhanced cooperative binding of oligonucleotides to form DNA duplexes mediated by metal ion chelation Chemical Communications. 1950-1951. PMID 12271689 DOI: 10.1039/B206054J |
0.359 |
|
| 2002 |
Ladame S, Harrison RJ, Neidle S, Balasubramanian S. Solid-phase synthesis of symmetrical 3,6-bispeptide-acridone conjugates. Organic Letters. 4: 2509-12. PMID 12123363 DOI: 10.1021/Ol026130P |
0.674 |
|
| 2001 |
Wallace MI, Ying L, Balasubramanian S, Klenerman D. Non-arrhenius kinetics for the loop closure of a DNA hairpin Proceedings of the National Academy of Sciences of the United States of America. 98: 5584-5589. PMID 11320222 DOI: 10.1073/Pnas.101523498 |
0.335 |
|
| 2001 |
Isalan M, Patel SD, Balasubramanian S, Choo Y. Selection of zinc fingers that bind single-stranded telomeric DNA in the G-quadruplex conformation Biochemistry. 40: 830-836. PMID 11170401 DOI: 10.1021/Bi001728V |
0.475 |
|
| 2001 |
Osborne MA, Barnes CL, Balasubramanian S, Klenerman D. Probing DNA Surface Attachment and Local Environment Using Single Molecule Spectroscopy Journal of Physical Chemistry B. 105: 3120-3126. DOI: 10.1021/Jp0038660 |
0.351 |
|
| 2000 |
Liu X, Balasubramanian S. Strategies for the synthesis of fluorescently labelled PNA. Tetrahedron Letters. 41: 6153-6156. PMID 18259605 DOI: 10.1016/S0040-4039(00)00996-5 |
0.572 |
|
| 2000 |
Osborne MA, Furey WS, Klenerman D, Balasubramanian S. Single-molecule analysis of DNA immobilized on microspheres. Analytical Chemistry. 72: 3678-81. PMID 10952560 DOI: 10.1021/Ac000129R |
0.318 |
|
| 1999 |
Lee HB, Balasubramanian S. Studies on a Dithiane-Protected Benzoin Photolabile Safety Catch Linker for Solid-Phase Synthesis. Journal of Organic Chemistry. 64: 3454-3460. PMID 11674652 DOI: 10.1021/Jo994991E |
0.314 |
|
| 1999 |
Harrison JG, Liu X, Balasubramanian S. Screening for oligonucleotide binding affinity by a convenient fluorescence competition assay. Nucleic Acids Research. 27: e14. PMID 10446257 DOI: 10.1093/Nar/27.17.E14-I |
0.628 |
|
| 1999 |
Harrison JG, Frier C, Laurant R, Dennis R, Raney KD, Balasubramanian S. Inhibition of human telomerase by PNA-cationic peptide conjugates. Bioorganic & Medicinal Chemistry Letters. 9: 1273-8. PMID 10340613 DOI: 10.1016/S0960-894X(99)00170-5 |
0.72 |
|
| 1997 |
Cheung YW, Abell C, Balasubramanian S. A Combinatorial Approach to Identifying Protein Tyrosine Phosphatase Substrates from a Phosphotyrosine Peptide Library Journal of the American Chemical Society. 119: 9568-9569. DOI: 10.1021/Ja971825K |
0.644 |
|
| 1997 |
Todd MH, Balasubramanian S, Abell C. Studies on the synthesis, characterisation and reactivity of aromatic diboronic acids Tetrahedron Letters. 38: 6781-6784. DOI: 10.1016/S0040-4039(97)01552-9 |
0.609 |
|
| 1997 |
Arumugam V, Routledge A, Abell C, Balasubramanian S. Synthesis of 2-oxindole derivatives via the intramolecular Heck reaction on solid support Tetrahedron Letters. 38: 6473-6476. DOI: 10.1016/S0040-4039(97)01481-0 |
0.757 |
|
| 1997 |
Routledge A, Abell C, Balasubramanian S. The use of a dithiane protected benzoin photolabile safety catch linker for solid-phase synthesis Tetrahedron Letters. 38: 1227-1230. DOI: 10.1016/S0040-4039(96)02478-1 |
0.681 |
|
| 1995 |
Bornemann S, Balasubramanian S, Coggins JR, Abell C, Lowe DJ, Thorneley RN. Escherichia coli chorismate synthase: a deuterium kinetic-isotope effect under single-turnover and steady-state conditions shows that a flavin intermediate forms before the C-(6proR)-H bond is cleaved. The Biochemical Journal. 305: 707-10. PMID 7848266 DOI: 10.1042/Bj3050707 |
0.44 |
|
| 1995 |
Balasubramanian S, Coggins JR, Abell C. Observation of a secondary tritium isotope effect in the chorismate synthase reaction. Biochemistry. 34: 341-8. PMID 7819217 DOI: 10.1021/Bi00001A042 |
0.443 |
|
| 1995 |
Carr RT, Balasubramanian S, Hawkins PC, Benkovic SJ. Mechanism of metal-independent hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase. Biochemistry. 34: 7525-32. PMID 7779797 DOI: 10.1021/Bi00022A028 |
0.411 |
|
| 1995 |
Bornemann S, Ramjee MK, Balasubramanian S, Abell C, Coggins JR, Lowe DJ, Thorneley RN. Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate. The Journal of Biological Chemistry. 270: 22811-5. PMID 7559411 DOI: 10.1074/Jbc.270.39.22811 |
0.495 |
|
| 1994 |
Balasubramanian S, Carr RT, Bender CJ, Peisach J, Benkovic SJ. Identification of metal ligands in Cu(II)-inhibited Chromobacterium violaceum phenylalanine hydroxylase by electron spin echo envelope modulation analysis of histidine to serine mutations. Biochemistry. 33: 8532-7. PMID 8031788 DOI: 10.1021/Bi00194A019 |
0.431 |
|
| 1994 |
Peliska JA, Balasubramanian S, Giedroc DP, Benkovic SJ. Recombinant HIV-1 nucleocapsid protein accelerates HIV-1 reverse transcriptase catalyzed DNA strand transfer reactions and modulates RNase H activity. Biochemistry. 33: 13817-23. PMID 7524664 DOI: 10.1021/Bi00250A036 |
0.482 |
|
| 1993 |
Balasubramanian S, Carr RT, Bender CJ, Peisach J, Benkovic SJ. Histidines 138 and 143 are copper binding ligands in Chromobacterium violaceum phenylalanine hydroxylase. Advances in Experimental Medicine and Biology. 338: 67-70. PMID 8304204 DOI: 10.1007/978-1-4615-2960-6_13 |
0.418 |
|
| 1992 |
Ramjee MN, Balasubramanian S, Abell C, Coggins JR, Davies GM, Hawkes TR, Lowe DJ, Thorneley RNF. Reaction of (6R)-6-fluoroEPSP with recombinant Escherichia coli chorismate synthase generates a stable flavin mononucleotide semiquinone radical Journal of the American Chemical Society. 114: 3151-3153. DOI: 10.1021/Ja00034A079 |
0.43 |
|
| 1991 |
Balasubramanian S, Davies GM, Coggins JR, Abell C. Inhibition of chorismate synthase by (6R)- and (6S)-6-fluoro-5-enolpyruvylshikimate 3-phosphate Journal of the American Chemical Society. 113: 8945-8946. DOI: 10.1021/Ja00023A051 |
0.425 |
|
| 1991 |
Balasubramanian S, Abell C. The synthesis of (6R)-[6-2H]- and (6S)-[6-2H]5-enolpyruvylshikimate-3-phosphate Tetrahedron Letters. 32: 963-966. DOI: 10.1016/S0040-4039(00)92131-2 |
0.439 |
|
| 1990 |
Balasubramanian S, Abell C, Coggins JR. Observation of an isotope effect in the chorismate synthase reaction Journal of the American Chemical Society. 112: 8581-8583. DOI: 10.1021/Ja00179A052 |
0.418 |
|
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