Yoshihiro Kawaoka - Publications

Affiliations: 
University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Molecular Biology, Microbiology

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Year Citation  Score
2024 Hoxie I, Vasilev K, Clark JJ, Bushfield K, Francis B, Loganathan M, Campbell JD, Yu D, Guan L, Gu C, Fan S, Tompkins SM, Neumann G, Kawaoka Y, Krammer F. A recombinant N2 neuraminidase-based CpG 1018® adjuvanted vaccine provides protection against challenge with heterologous influenza viruses in mice and hamsters. Vaccine. 42: 126269. PMID 39241354 DOI: 10.1016/j.vaccine.2024.126269  0.486
2024 Neumann G, Kawaoka Y. Highly pathogenic H5N1 avian influenza virus outbreak in cattle: the knowns and unknowns. Nature Reviews. Microbiology. PMID 39060613 DOI: 10.1038/s41579-024-01087-1  0.623
2024 Eiden J, Fierro C, White A, Davis M, Rhee M, Turner M, Murray B, Herber R, Aitchison R, Marshall D, Moser MJ, Belshe R, Greenberg H, Coelingh K, Kawaoka Y, et al. Safety and immunogenicity of the intranasal H3N2 M2-deficient single-replication influenza vaccine alone or coadministered with an inactivated influenza vaccine (Fluzone High-Dose Quadrivalent) in adults aged 65-85 years in the USA: a multicentre, randomised, double-blind, double-dummy, phase 1b trial. The Lancet. Infectious Diseases. PMID 39004096 DOI: 10.1016/S1473-3099(24)00351-7  0.397
2024 Eisfeld AJ, Biswas A, Guan L, Gu C, Maemura T, Trifkovic S, Wang T, Babujee L, Dahn R, Halfmann PJ, Barnhardt T, Neumann G, Suzuki Y, Thompson A, Swinford AK, ... ... Kawaoka Y, et al. Pathogenicity and transmissibility of bovine H5N1 influenza virus. Nature. PMID 38977017 DOI: 10.1038/s41586-024-07766-6  0.632
2024 Takashita E, Ichikawa M, Fujisaki S, Morita H, Nagata S, Miura H, Watanabe S, Hasegawa H, Kawaoka Y. Antiviral susceptibility of SARS-CoV-2 and influenza viruses from 3 co-infected pediatric patients. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 107134. PMID 38944411 DOI: 10.1016/j.ijid.2024.107134  0.586
2024 Shimizu K, Kawakami C, Matsuzaki Y, Fujisaki S, Nagata S, Morita H, Watanabe K, Miura H, Momoki T, Saikusa M, Ozawa H, Kumazaki M, Usuku S, Tanaka N, Senda R, ... ... Kawaoka Y, et al. Monitoring Influenza C and D Viruses in Patients With Respiratory Diseases in Japan, January 2018 to March 2023. Influenza and Other Respiratory Viruses. 18: e13345. PMID 38923307 DOI: 10.1111/irv.13345  0.553
2024 Guan L, Eisfeld AJ, Pattinson D, Gu C, Biswas A, Maemura T, Trifkovic S, Babujee L, Presler R, Dahn R, Halfmann PJ, Barnhardt T, Neumann G, Thompson A, Swinford AK, ... ... Kawaoka Y, et al. Cow's Milk Containing Avian Influenza A(H5N1) Virus - Heat Inactivation and Infectivity in Mice. The New England Journal of Medicine. PMID 38785313 DOI: 10.1056/NEJMc2405495  0.524
2024 Guan L, Babujee L, Presler R, Pattinson D, Nguyen HLK, Hoang VMP, Le MQ, Bakel HV, Kawaoka Y, Neumann G. Avian H6 Influenza Viruses in Vietnamese Live Bird Markets during 2018-2021. Viruses. 16. PMID 38543733 DOI: 10.3390/v16030367  0.569
2024 Hill-Batorski L, Bowen R, Bielefeldt-Ohmann H, Moser MJ, Matejka SM, Marshall D, Kawaoka Y, Neumann G, Bilsel P. Mucosal immunization with dual influenza/COVID-19 single-replication virus vector protects hamsters from SARS-CoV-2 challenge. Vaccine. PMID 38508930 DOI: 10.1016/j.vaccine.2024.03.040  0.522
2024 Gu C, Fan S, Dahn R, Babujee L, Chiba S, Guan L, Maemura T, Pattinson D, Neumann G, Kawaoka Y. Characterization of a human H3N8 influenza virus. Ebiomedicine. 101: 105034. PMID 38408394 DOI: 10.1016/j.ebiom.2024.105034  0.601
2024 Fan S, Kong H, Babujee L, Presler R, Jester P, Burke D, Pattinson D, Barr I, Smith D, Neumann G, Kawaoka Y. Assessment of the antigenic evolution of a clade 6B.1 human H1N1pdm influenza virus revealed differences between ferret and human convalescent sera. Ebiomedicine. 101: 105013. PMID 38364702 DOI: 10.1016/j.ebiom.2024.105013  0.568
2024 Halfmann PJ, Loeffler K, Duffy A, Kuroda M, Yang JE, Wright ER, Kawaoka Y, Kane RS. Broad protection against clade 1 sarbecoviruses after a single immunization with cocktail spike-protein-nanoparticle vaccine. Nature Communications. 15: 1284. PMID 38346966 DOI: 10.1038/s41467-024-45495-6  0.338
2024 Hagihara M, Hayashi H, Nakashima S, Imai Y, Nakano H, Uchida T, Inoue M, Sakai-Tagawa Y, Ito M, Yamayoshi S, Iwatsuki-Horimoto K, Suzuki Y, Kawaoka Y. Clinical Efficacy of Imdevimab/Casirivimab for Persistent Omicron SARS-CoV-2 Infection in Patients with Hematological Malignancies. Internal Medicine (Tokyo, Japan). PMID 38171874 DOI: 10.2169/internalmedicine.2900-23  0.301
2023 Uraki R, Kiso M, Iwatsuki-Horimoto K, Yamayoshi S, Ito M, Chiba S, Sakai-Tagawa Y, Imai M, Kashima Y, Koga M, Fuwa N, Okumura N, Hojo M, Iwamoto N, Kato H, ... ... Kawaoka Y, et al. Characterization of a SARS-CoV-2 EG.5.1 clinical isolate in vitro and in vivo. Cell Reports. 42: 113580. PMID 38103202 DOI: 10.1016/j.celrep.2023.113580  0.37
2023 Uraki R, Ito M, Kiso M, Yamayoshi S, Iwatsuki-Horimoto K, Sakai-Tagawa Y, Imai M, Koga M, Yamamoto S, Adachi E, Saito M, Tsutsumi T, Otani A, Fukushi S, Watanabe S, ... ... Kawaoka Y, et al. Antiviral efficacy against and replicative fitness of an XBB.1.9.1 clinical isolate. Iscience. 26: 108147. PMID 37876803 DOI: 10.1016/j.isci.2023.108147  0.304
2023 Maemura T, Guan L, Gu C, Eisfeld A, Biswas A, Halfmann P, Neumann G, Kawaoka Y. Characterization of highly pathogenic clade 2.3.4.4b H5N1 mink influenza viruses. Ebiomedicine. 97: 104827. PMID 37812908 DOI: 10.1016/j.ebiom.2023.104827  0.54
2023 Kikuchi C, Antonopoulos A, Wang S, Maemura T, Karamanska R, Lee C, Thompson AJ, Dell A, Kawaoka Y, Haslam SM, Paulson JC. Glyco-engineered MDCK cells display preferred receptors of H3N2 influenza absent in eggs used for vaccines. Nature Communications. 14: 6178. PMID 37794004 DOI: 10.1038/s41467-023-41908-0  0.502
2023 Chiba S, Halfmann PJ, Iida S, Hirata Y, Sato Y, Kuroda M, Armbrust T, Spyra S, Suzuki T, Kawaoka Y. Recombinant spike protein vaccines coupled with adjuvants that have different modes of action induce protective immunity against SARS-CoV-2. Vaccine. PMID 37635002 DOI: 10.1016/j.vaccine.2023.08.054  0.369
2023 Guan L, Ping J, Lopes TJS, Fan S, Presler R, Neumann G, Kawaoka Y. Development of an Enhanced High-Yield Influenza Vaccine Backbone in Embryonated Chicken Eggs. Vaccines. 11. PMID 37631932 DOI: 10.3390/vaccines11081364  0.554
2023 Kuroda M, Halfmann PJ, Thackray LB, Diamond MS, Feldmann H, Marzi A, Kawaoka Y. An antiviral role for TRIM14 in Ebola virus infection. The Journal of Infectious Diseases. PMID 37562033 DOI: 10.1093/infdis/jiad325  0.433
2023 Guan L, Babujee L, Browning VL, Presler R, Pattinson D, Nguyen HLK, Hoang VMP, Le MQ, van Bakel H, Neumann G, Kawaoka Y. Continued Circulation of Highly Pathogenic H5 Influenza Viruses in Vietnamese Live Bird Markets in 2018-2021. Viruses. 15. PMID 37515281 DOI: 10.3390/v15071596  0.573
2023 Chiba S, Kong H, Neumann G, Kawaoka Y. Influenza H3 hemagglutinin vaccine with scrambled immunodominant epitopes elicits antibodies directed toward immunosubdominant head epitopes. Mbio. e0062223. PMID 37466314 DOI: 10.1128/mbio.00622-23  0.348
2023 Kane R, Halfmann P, Loeffler K, Duffy A, Kuroda M, Kawaoka Y. Broad Protection Against Clade 1 Sarbecoviruses After a Single Immunization with Cocktail Spike-Protein-Nanoparticle Vaccine. Research Square. PMID 37461652 DOI: 10.21203/rs.3.rs-3088907/v1  0.331
2023 Kiso M, Yamayoshi S, Iida S, Furusawa Y, Hirata Y, Uraki R, Imai M, Suzuki T, Kawaoka Y. In vitro and in vivo characterization of SARS-CoV-2 resistance to ensitrelvir. Nature Communications. 14: 4231. PMID 37454219 DOI: 10.1038/s41467-023-40018-1  0.468
2023 Kiso M, Furusawa Y, Uraki R, Imai M, Yamayoshi S, Kawaoka Y. In vitro and in vivo characterization of SARS-CoV-2 strains resistant to nirmatrelvir. Nature Communications. 14: 3952. PMID 37402789 DOI: 10.1038/s41467-023-39704-x  0.449
2023 Halfmann PJ, Borisevich V, Levine CB, Mire CE, Fenton KA, Geisbert TW, Kawaoka Y, Cross RW. The Mucin-like Domain of the Ebola Glycoprotein Does Not Impact Virulence or Pathogenicity in Ferrets. The Journal of Infectious Diseases. PMID 37379580 DOI: 10.1093/infdis/jiad240  0.441
2023 Moser MJ, Hill-Batorski L, Bowen RA, Matejka SM, Marshall D, Kawaoka Y, Neumann G, Bilsel P. Intranasal Single-Replication Influenza Vector Induces Cross-Reactive Serum and Mucosal Antibodies against SARS-CoV-2 Variants. Vaccines. 11. PMID 37376452 DOI: 10.3390/vaccines11061063  0.446
2023 Guan L, Zhong G, Fan S, Plisch EM, Presler R, Gu C, Babujee L, Pattinson D, Le Khanh Nguyen H, Hoang VMP, Le MQ, van Bakel H, Neumann G, Kawaoka Y. Highly Pathogenic H5 Influenza Viruses Isolated between 2016 and 2017 in Vietnamese Live Bird Markets. Viruses. 15. PMID 37243179 DOI: 10.3390/v15051093  0.531
2023 Kiso M, Yamayoshi S, Kawaoka Y. Efficacy of favipiravir against influenza virus resistant to both baloxavir and neuraminidase inhibitors. The Journal of Antimicrobial Chemotherapy. PMID 37209424 DOI: 10.1093/jac/dkad145  0.379
2023 Hill-Batorski L, Hatta Y, Moser MJ, Sarawar S, Neumann G, Kawaoka Y, Bilsel P. Quadrivalent Formulation of Intranasal Influenza Vaccine M2SR (M2-Deficient Single Replication) Protects against Drifted Influenza A and B Virus Challenge. Vaccines. 11. PMID 37112710 DOI: 10.3390/vaccines11040798  0.414
2023 Kawaoka Y. Addressing the Threat of Emerging Viral Infections. The Keio Journal of Medicine. 72: 27. PMID 36967128 DOI: 10.2302/kjm.ABSTRACT_72_1-2  0.603
2023 Soga T, Duong C, Pattinson D, Sakai-Tagawa Y, Tokita A, Izumida N, Nishino T, Hagiwara H, Wada N, Miyamoto Y, Kuroki H, Hayashi Y, Seki M, Kasuya N, Koga M, ... ... Kawaoka Y, et al. Characterization of Influenza A(H1N1)pdm09 Viruses Isolated in the 2018-2019 and 2019-2020 Influenza Seasons in Japan. Viruses. 15. PMID 36851749 DOI: 10.3390/v15020535  0.603
2023 Neumann G, Kawaoka Y. The COVID-19 Pandemic-A Potential Role for Antivirals in Mitigating Pandemics. Viruses. 15. PMID 36851516 DOI: 10.3390/v15020303  0.353
2023 McLean HQ, Petrie JG, Hanson KE, Meece JK, Rolfes MA, Sylvester GC, Neumann G, Kawaoka Y, Belongia EA. Interim Estimates of 2022-23 Seasonal Influenza Vaccine Effectiveness - Wisconsin, October 2022-February 2023. Mmwr. Morbidity and Mortality Weekly Report. 72: 201-205. PMID 36821715 DOI: 10.15585/mmwr.mm7208a1  0.522
2023 Braun KM, Haddock Iii LA, Crooks CM, Barry GL, Lalli J, Neumann G, Watanabe T, Imai M, Yamayoshi S, Ito M, Moncla LH, Koelle K, Kawaoka Y, Friedrich TC. Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammals. Virus Evolution. 9: vead004. PMID 36814938 DOI: 10.1093/ve/vead004  0.585
2023 Saitoh H, Sakai-Tagawa Y, Nagasawa S, Torimitsu S, Kubota K, Hirata Y, Iwatsuki-Horimoto K, Motomura A, Ishii N, Okaba K, Horioka K, Abe H, Ikemura M, Rokutan H, Hinata M, ... ... Kawaoka Y, et al. High titers of infectious SARS-CoV-2 in COVID-19 corpses. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. PMID 36754229 DOI: 10.1016/j.ijid.2023.01.046  0.322
2023 Neumann G, Kawaoka Y. Which Virus Will Cause the Next Pandemic? Viruses. 15. PMID 36680238 DOI: 10.3390/v15010199  0.468
2022 Takashita E, Watanabe S, Hasegawa H, Kawaoka Y. Are twindemics occurring? Influenza and Other Respiratory Viruses. 17: e13090. PMID 36567444 DOI: 10.1111/irv.13090  0.457
2022 Sarawar S, Gabaglia CR, Sanchez A, Hatta Y, Dias P, Neumann G, Kawaoka Y, Bilsel P. Longevity and Mechanism of Heterosubtypic Protection Induced by M2SR (M2-Deficient Single-Replication) Live Influenza Virus Vaccine in Mice. Vaccines. 10. PMID 36560540 DOI: 10.3390/vaccines10122131  0.445
2022 Chiba S, Hatta M, Pattinson D, Yasuhara A, Neumann G, Kawaoka Y. Ferret model to mimic the sequential exposure of humans to historical H3N2 influenza viruses. Vaccine. PMID 36517323 DOI: 10.1016/j.vaccine.2022.12.005  0.528
2022 Boon ACM, Darling TL, Halfmann PJ, Franks J, Webby RJ, Barouch DH, Port JR, Munster VJ, Diamond MS, Kawaoka Y. Reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters. Plos Pathogens. 18: e1010970. PMID 36459536 DOI: 10.1371/journal.ppat.1010970  0.52
2022 Eiden J, Fierro C, Schwartz H, Adams M, Ellis KJ, Aitchison R, Herber R, Hatta Y, Marshall D, Moser MJ, Belshe R, Greenberg H, Coelingh K, Kawaoka Y, Neumann G, et al. Intranasal M2SR (M2-deficient Single Replication) H3N2 Influenza Vaccine Provides Enhanced Mucosal and Serum Antibodies In Adults. The Journal of Infectious Diseases. PMID 36350017 DOI: 10.1093/infdis/jiac433  0.407
2022 Yasuhara A, Yamayoshi S, Kiso M, Sakai-Tagawa Y, Okuda M, Kawaoka Y. A broadly protective human monoclonal antibody targeting the sialidase activity of influenza A and B virus neuraminidases. Nature Communications. 13: 6602. PMID 36329075 DOI: 10.1038/s41467-022-34521-0  0.53
2022 Imai M, Takada K, Kawaoka Y. Receptor-Binding Specificity of Influenza Viruses. Methods in Molecular Biology (Clifton, N.J.). 2556: 79-96. PMID 36175629 DOI: 10.1007/978-1-0716-2635-1_8  0.601
2022 Ohta M, Kambayashi Y, Mita H, Kuroda T, Bannai H, Tsujimura K, Yamanaka T, Garvey M, Cullinane A, Yamayoshi S, Kawaoka Y, Nemoto M. Protective efficacy of a reverse genetics-derived inactivated vaccine against equine influenza virus in horses. Vaccine. PMID 36175213 DOI: 10.1016/j.vaccine.2022.09.047  0.453
2022 Meng F, Yang H, Qu Z, Chen Y, Zhang Y, Zhang Y, Liu L, Zeng X, Li C, Kawaoka Y, Chen H. A Eurasian avian-like H1N1 swine influenza reassortant virus became pathogenic and highly transmissible due to mutations in its PA gene. Proceedings of the National Academy of Sciences of the United States of America. 119: e2203919119. PMID 35969783 DOI: 10.1073/pnas.2203919119  0.615
2022 Fan S, Gu C, Kong H, Guan L, Neumann G, Kawaoka Y. Influenza Viruses Suitable for Studies in Syrian Hamsters. Viruses. 14. PMID 35893694 DOI: 10.3390/v14081629  0.56
2022 Belser JA, Lau EHY, Barclay W, Barr IG, Chen H, Fouchier RAM, Hatta M, Herfst S, Kawaoka Y, Lakdawala SS, Lee LYY, Neumann G, Peiris M, Perez DR, Russell C, et al. Robustness of the Ferret Model for Influenza Risk Assessment Studies: a Cross-Laboratory Exercise. Mbio. e0117422. PMID 35862762 DOI: 10.1128/mbio.01174-22  0.461
2022 Uraki R, Kiso M, Iida S, Imai M, Takashita E, Kuroda M, Halfmann PJ, Loeber S, Maemura T, Yamayoshi S, Fujisaki S, Wang Z, Ito M, Ujie M, Iwatsuki-Horimoto K, ... ... Kawaoka Y, et al. Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2. Nature. PMID 35576972 DOI: 10.1038/s41586-022-04856-1  0.335
2022 Chong Z, Karl CE, Halfmann PJ, Kawaoka Y, Winkler ES, Keeler SP, Holtzman MJ, Yu J, Diamond MS. Nasally delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron. Cell Reports. 39: 110799. PMID 35523172 DOI: 10.1016/j.celrep.2022.110799  0.311
2022 Okuda M, Sakai-Tagawa Y, Koga M, Koibuchi T, Kikuchi T, Adachi E, Lim LA, Yamamoto S, Yotsuyanagi H, Negishi K, Jubishi D, Yamayoshi S, Kawaoka Y. Immunological correlates of prevention of the onset of seasonal H3N2 influenza. The Journal of Infectious Diseases. PMID 35478039 DOI: 10.1093/infdis/jiac152  0.543
2022 Murakami J, Shibata A, Neumann G, Imai M, Watanabe T, Kawaoka Y. Characterization of H9N2 Avian Influenza Viruses Isolated from Poultry Products in a Mouse Model. Viruses. 14. PMID 35458458 DOI: 10.3390/v14040728  0.614
2022 Halfmann PJ, Kuroda M, Maemura T, Chiba S, Armbrust T, Wright R, Balaram A, Florek KR, Bateman AC, Kawaoka Y. Efficacy of vaccination and previous infection against the Omicron BA.1 variant in Syrian hamsters. Cell Reports. 39: 110688. PMID 35421378 DOI: 10.1016/j.celrep.2022.110688  0.338
2022 Kawaoka Y, Uraki R, Kiso M, Iida S, Imai M, Takashita E, Kuroda M, Halfmann P, Loeber S, Maemura T, Yamayoshi S, Fujisaki S, Wang Z, Ito M, Ujie M, et al. Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2. Research Square. PMID 35233565 DOI: 10.21203/rs.3.rs-1375091/v1  0.335
2022 Neumann G, Kawaoka Y. Seasonality of influenza and other respiratory viruses. Embo Molecular Medicine. e15352. PMID 35157360 DOI: 10.15252/emmm.202115352  0.536
2022 Halfmann PJ, Kuroda M, Armbrust T, Accola M, Valdez R, Kowalski-Dobson T, Rehrauer W, Gordon A, Kawaoka Y. Long-term, infection-acquired immunity against the SARS-CoV-2 Delta variant in a hamster model. Cell Reports. 38: 110394. PMID 35139368 DOI: 10.1016/j.celrep.2022.110394  0.348
2022 Yoshimi K, Takeshita K, Yamayoshi S, Shibumura S, Yamauchi Y, Yamamoto M, Yotsuyanagi H, Kawaoka Y, Mashimo T. CRISPR-Cas3-based diagnostics for SARS-CoV-2 and influenza virus. Iscience. 25: 103830. PMID 35128347 DOI: 10.1016/j.isci.2022.103830  0.392
2022 Chong Z, Karl CE, Halfmann PJ, Kawaoka Y, Winkler ES, Yu J, Diamond MS. Nasally-delivered interferon-λ protects mice against upper and lower respiratory tract infection of SARS-CoV-2 variants including Omicron. Biorxiv : the Preprint Server For Biology. PMID 35118466 DOI: 10.1101/2022.01.21.477296  0.303
2022 Chiba S, Kiso M, Nakajima N, Iida S, Maemura T, Kuroda M, Sato Y, Ito M, Okuda M, Yamada S, Iwatsuki-Horimoto K, Watanabe T, Imai M, Armbrust T, Baric RS, ... ... Kawaoka Y, et al. Co-administration of Favipiravir and the Remdesivir Metabolite GS-441524 Effectively Reduces SARS-CoV-2 Replication in the Lungs of the Syrian Hamster Model. Mbio. e0304421. PMID 35100870 DOI: 10.1128/mbio.03044-21  0.403
2022 Sugita Y, Matsunami H, Kawaoka Y, Noda T, Wolf M. Author Correction: Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex at 3.6 Å resolution. Nature. PMID 34992296 DOI: 10.1038/s41586-021-04304-6  0.308
2022 Kong X, Guan L, Shi J, Kong H, Zhang Y, Zeng X, Tian G, Liu L, Li C, Kawaoka Y, Deng G, Chen H. A single-amino-acid mutation at position 225 in hemagglutinin attenuates H5N6 influenza virus in mice. Emerging Microbes & Infections. 10: 2052-2061. PMID 34686117 DOI: 10.1080/22221751.2021.1997340  0.57
2021 Eiden J, Gordon G, Fierro C, Herber R, Aitchison R, Belshe R, Greenberg H, Hoft D, Hatta Y, Moser MJ, Tary-Lehmann M, Kawaoka Y, Neumann G, Radspinner P, Bilsel P. Safety and Immunogenicity of M2-Deficient, Single Replication, Live Influenza Vaccine (M2SR) in Adults. Vaccines. 9. PMID 34960134 DOI: 10.3390/vaccines9121388  0.37
2021 Neumann G, Kawaoka Y. Quo Vadis Influenza? China Cdc Weekly. 3: 1046-1048. PMID 34934513 DOI: 10.46234/ccdcw2021.254  0.527
2021 Halfmann P, Nakajima N, Sato Y, Takahashi K, Accola M, Chibo S, Fan S, Neumann G, Rehrauer W, Suzuki T, Kawaoka Y. SARS-CoV-2 Interference of Influenza Virus Replication in Syrian Hamsters. The Journal of Infectious Diseases. PMID 34875072 DOI: 10.1093/infdis/jiab587  0.61
2021 Kong H, Fan S, Takada K, Imai M, Neumann G, Kawaoka Y. H3N2 Influenza Viruses with 12- or 16-Amino Acid Deletions in the Receptor-Binding Region of Their Hemagglutinin Protein. Mbio. e0151221. PMID 34872354 DOI: 10.1128/mBio.01512-21  0.456
2021 Saito A, Irie T, Suzuki R, Maemura T, Nasser H, Uriu K, Kosugi Y, Shirakawa K, Sadamasu K, Kimura I, Ito J, Wu J, Iwatsuki-Horimoto K, Ito M, Yamayoshi S, ... ... Kawaoka Y, et al. Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation. Nature. PMID 34823256 DOI: 10.1038/s41586-021-04266-9  0.357
2021 Ohtsuka J, Imai M, Fukumura M, Maeda M, Eguchi A, Ono R, Maemura T, Ito M, Yamayoshi S, Kataoka Y, Kawaoka Y, Nosaka T. Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2. Iscience. 103379. PMID 34805782 DOI: 10.1016/j.isci.2021.103379  0.375
2021 Eiden J, Volckaert B, Rudenko O, Aitchison R, Herber R, Belshe R, Greenberg H, Coelingh K, Marshall D, Kawaoka Y, Neumann G, Bilsel P. Single Replication M2SR Influenza Vaccine Induced Immune Responses Associated with Protection Against Human Challenge with Highly Drifted H3N2 Influenza Strain. The Journal of Infectious Diseases. PMID 34323977 DOI: 10.1093/infdis/jiab374  0.449
2021 Hatakeyama D, Shoji M, Ogata S, Masuda T, Nakano M, Komatsu T, Saitoh A, Makiyama K, Tsuneishi H, Miyatake A, Takahira M, Nishikawa E, Ohkubo A, Noda T, Kawaoka Y, et al. Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity. The Febs Journal. PMID 34270849 DOI: 10.1111/febs.16123  0.446
2021 Saito M, Itoh Y, Yasui F, Munakata T, Yamane D, Ozawa M, Ito R, Katoh T, Ishigaki H, Nakayama M, Shichinohe S, Yamaji K, Yamamoto N, Ikejiri A, Honda T, ... ... Kawaoka Y, et al. Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models. Nature Communications. 12: 2654. PMID 33976181 DOI: 10.1038/s41467-021-22964-w  0.563
2021 Nemoto M, Ohta M, Yamanaka T, Kambayashi Y, Bannai H, Tsujimura K, Yamayoshi S, Kawaoka Y, Cullinane A. Antigenic differences between equine influenza virus vaccine strains and Florida sublineage clade 1 strains isolated in Europe in 2019. Veterinary Journal (London, England : 1997). 272: 105674. PMID 33941332 DOI: 10.1016/j.tvjl.2021.105674  0.351
2021 Takashita E, Kawakami C, Momoki T, Saikusa M, Shimizu K, Ozawa H, Kumazaki M, Usuku S, Tanaka N, Okubo I, Morita H, Nagata S, Watanabe S, Hasegawa H, Kawaoka Y. Increased risk of rhinovirus infection in children during the coronavirus disease-19 pandemic. Influenza and Other Respiratory Viruses. PMID 33715290 DOI: 10.1111/irv.12854  0.463
2021 Braun KM, Moreno GK, Halfmann PJ, Hodcroft EB, Baker DA, Boehm EC, Weiler AM, Haj AK, Hatta M, Chiba S, Maemura T, Kawaoka Y, Koelle K, O'Connor DH, Friedrich TC. Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck. Plos Pathogens. 17: e1009373. PMID 33635912 DOI: 10.1371/journal.ppat.1009373  0.301
2021 Kong H, Burke DF, da Silva Lopes TJ, Takada K, Imai M, Zhong G, Hatta M, Fan S, Chiba S, Smith D, Neumann G, Kawaoka Y. Plasticity of the Influenza Virus H5 HA Protein. Mbio. 12. PMID 33563825 DOI: 10.1128/mBio.03324-20  0.467
2021 Ohta M, Bannai H, Kambayashi Y, Tamura N, Tsujimura K, Yamayoshi S, Kawaoka Y, Nemoto M. Growth properties and immunogenicity of a virus generated by reverse genetics for an inactivated equine influenza vaccine. Equine Veterinary Journal. 54: 139-144. PMID 33527477 DOI: 10.1111/evj.13431  0.401
2021 Alzhanova D, Corcoran K, Bailey AG, Long K, Taft-Benz S, Graham RL, Broussard GS, Heise M, Neumann G, Halfmann P, Kawaoka Y, Baric RS, Damania B, Dittmer DP. Novel modulators of p53-signaling encoded by unknown genes of emerging viruses. Plos Pathogens. 17: e1009033. PMID 33411764 DOI: 10.1371/journal.ppat.1009033  0.423
2020 Yamayoshi S, Kawaoka Y. Emergence of SARS-CoV-2 and its outlook. Global Health & Medicine. 2: 1-2. PMID 33330766 DOI: 10.35772/ghm.2020.01009  0.37
2020 Yamayoshi S, Sakai-Tagawa Y, Koga M, Akasaka O, Nakachi I, Koh H, Maeda K, Adachi E, Saito M, Nagai H, Ikeuchi K, Ogura T, Baba R, Fujita K, Fukui T, ... ... Kawaoka Y, et al. Comparison of Rapid Antigen Tests for COVID-19. Viruses. 12. PMID 33322035 DOI: 10.3390/v12121420  0.346
2020 Hou YJ, Chiba S, Halfmann P, Ehre C, Kuroda M, Dinnon KH, Leist SR, Schäfer A, Nakajima N, Takahashi K, Lee RE, Mascenik TM, Graham R, Edwards CE, Tse LV, ... ... Kawaoka Y, et al. SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo. Science (New York, N.Y.). PMID 33184236 DOI: 10.1126/science.abe8499  0.433
2020 Ueki H, Furusawa Y, Iwatsuki-Horimoto K, Imai M, Kabata H, Nishimura H, Kawaoka Y. Effectiveness of Face Masks in Preventing Airborne Transmission of SARS-CoV-2. Msphere. 5. PMID 33087517 DOI: 10.1128/mSphere.00637-20  0.307
2020 Hou YJ, Chiba S, Halfmann P, Ehre C, Kuroda M, Dinnon KH, Leist SR, Schäfer A, Nakajima N, Takahashi K, Lee RE, Mascenik TM, Edwards CE, Tse LV, Boucher RC, ... ... Kawaoka Y, et al. SARS-CoV-2 D614G Variant Exhibits Enhanced Replication and Earlier Transmission . Biorxiv : the Preprint Server For Biology. PMID 33024969 DOI: 10.1101/2020.09.28.317685  0.49
2020 Westmark CJ, Kiso M, Halfmann P, Westmark PR, Kawaoka Y. Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction Frontiers in Cell and Developmental Biology. 8. PMID 32984339 DOI: 10.3389/Fcell.2020.00856  0.341
2020 Imai M, Iwatsuki-Horimoto K, Hatta M, Loeber S, Halfmann PJ, Nakajima N, Watanabe T, Ujie M, Takahashi K, Ito M, Yamada S, Fan S, Chiba S, Kuroda M, Guan L, ... ... Kawaoka Y, et al. Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development. Proceedings of the National Academy of Sciences of the United States of America. PMID 32571934 DOI: 10.1073/Pnas.2009799117  0.401
2020 Yamamoto M, Kiso M, Sakai-Tagawa Y, Iwatsuki-Horimoto K, Imai M, Takeda M, Kinoshita N, Ohmagari N, Gohda J, Semba K, Matsuda Z, Kawaguchi Y, Kawaoka Y, Inoue JI. The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner. Viruses. 12. PMID 32532094 DOI: 10.3390/V12060629  0.355
2020 Kuroda M, Halfmann PJ, Hill-Batorski L, Ozawa M, Lopes TJS, Neumann G, Schoggins JW, Rice CM, Kawaoka Y. Identification of interferon-stimulated genes that attenuate Ebola virus infection. Nature Communications. 11: 2953. PMID 32528005 DOI: 10.1038/S41467-020-16768-7  0.605
2020 Fukuyama S, Iwatsuki-Horimoto K, Kiso M, Nakajima N, Gregg RW, Katsura H, Tomita Y, Maemura T, da Silva Lopes TJ, Watanabe T, Shoemaker JE, Hasegawa H, Yamayoshi S, Kawaoka Y. Pathogenesis of influenza A(H7N9) virus in aged non-human primates. The Journal of Infectious Diseases. PMID 32433769 DOI: 10.1093/Infdis/Jiaa267  0.56
2020 Halfmann PJ, Hatta M, Chiba S, Maemura T, Fan S, Takeda M, Kinoshita N, Hattori SI, Sakai-Tagawa Y, Iwatsuki-Horimoto K, Imai M, Kawaoka Y. Transmission of SARS-CoV-2 in Domestic Cats. The New England Journal of Medicine. PMID 32402157 DOI: 10.1056/Nejmc2013400  0.45
2020 Feng H, Nakatsu S, Lopes TJDS, Imai M, Yamayoshi S, Yamashita M, Watanabe T, Kawaoka Y. Identification of Novel Adjuvants for Ebola Virus-Like Particle Vaccine. Vaccines. 8. PMID 32397625 DOI: 10.3390/Vaccines8020215  0.524
2020 Kiso M, Yamayoshi S, Kawaoka Y. Triple combination therapy of favipiravir plus two monoclonal antibodies eradicates influenza virus from nude mice. Communications Biology. 3: 219. PMID 32382088 DOI: 10.1038/s42003-020-0952-y  0.525
2020 Azekawa S, Namkoong H, Mitamura K, Kawaoka Y, Saito F. Co-infection with SARS-CoV-2 and influenza A virus Idcases. 20. PMID 32368495 DOI: 10.1016/J.Idcr.2020.E00775  0.549
2020 Martinez-Sobrido L, Blanco-Lobo P, Rodriguez L, Fitzgerald T, Zhang H, Nguyen P, Anderson CS, Holden-Wiltse J, Bandyopadhyay S, Nogales A, DeDiego ML, Wasik BR, Miller BL, Henry C, Wilson PC, ... ... Kawaoka Y, et al. Characterizing Emerging Canine H3 Influenza Viruses. Plos Pathogens. 16: e1008409. PMID 32287326 DOI: 10.1371/Journal.Ppat.1008409  0.579
2020 Neumann G, Kawaoka Y. Optimization of animal models to better predict influenza vaccine efficacy (VA) Vaccine. 38: 2749-2750. PMID 32145878 DOI: 10.1016/J.Vaccine.2020.01.102  0.411
2020 Yamaji R, Saad MD, Davis CT, Swayne DE, Wang D, Wong FYK, McCauley JW, Peiris JSM, Webby RJ, Fouchier RAM, Kawaoka Y, Zhang W. Pandemic potential of highly pathogenic avian influenza clade 2.3.4.4 A(H5) viruses. Reviews in Medical Virology. e2099. PMID 32135031 DOI: 10.1002/Rmv.2099  0.609
2020 Maemura T, Fukuyama S, Kawaoka Y. High Levels of miR-483-3p Are Present in Serum Exosomes Upon Infection of Mice With Highly Pathogenic Avian Influenza Virus. Frontiers in Microbiology. 11: 144. PMID 32117163 DOI: 10.3389/Fmicb.2020.00144  0.515
2020 Watanabe T, Kawaoka Y. Villains or heroes? The raison d'être of viruses. Clinical and Translational Immunology. 9. PMID 32099651 DOI: 10.1002/Cti2.1114  0.551
2020 Mitake H, Yasuhara A, Lopes TJS, Tagawa-Sakai Y, Shimizu K, Ozawa H, Kawakami C, Morikawa S, Sugaya N, Watanabe T, Kawaoka Y. Comparison of the Pathogenicity in Mice of A(H1N1)pdm09 Viruses Isolated between 2009 and 2015 in Japan. Viruses. 12. PMID 32013144 DOI: 10.3390/V12020155  0.657
2020 Ueki H, Wang I, Zhao D, Gunzer M, Kawaoka Y. Multicolor two-photon imaging of in vivo cellular pathophysiology upon influenza virus infection using the two-photon IMPRESS. Nature Protocols. 15: 1041-1065. PMID 31996843 DOI: 10.1038/S41596-019-0275-Y  0.446
2020 Kato-Miyashita S, Sakai-Tagawa Y, Yamashita M, Iwatsuki-Horimoto K, Ito M, Tokita A, Hagiwara H, Izumida N, Nishino T, Wada N, Koga M, Adachi E, Jubishi D, Yotsuyanagi H, Kawaoka Y, et al. Antigenic variants of influenza B viruses isolated in Japan during the 2017-2018 and 2018-2019 influenza seasons. Influenza and Other Respiratory Viruses. PMID 31955521 DOI: 10.1111/Irv.12713  0.603
2020 Furuyama W, Reynolds P, Haddock E, Meade-White K, Quynh Le M, Kawaoka Y, Feldmann H, Marzi A. A single dose of a vesicular stomatitis virus-based influenza vaccine confers rapid protection against H5 viruses from different clades. Npj Vaccines. 5: 4. PMID 31934358 DOI: 10.1038/s41541-019-0155-z  0.543
2020 Li X, Shi J, Guo J, Deng G, Zhang Q, Wang J, He X, Wang K, Chen J, Li Y, Fan J, Kong H, Gu C, Guan Y, Suzuki Y, ... Kawaoka Y, et al. Correction: Genetics, Receptor Binding Property, and Transmissibility in Mammals of Naturally Isolated H9N2 Avian Influenza Viruses. Plos Pathogens. 16: e1008284. PMID 31914139 DOI: 10.1371/journal.ppat.1008284  0.441
2020 Kiso M, Yamayoshi S, Murakami J, Kawaoka Y. Baloxavir Marboxil Treatment of Nude Mice Infected With Influenza A Virus. The Journal of Infectious Diseases. 221: 1699-1702. PMID 31837268 DOI: 10.1093/Infdis/Jiz665  0.572
2019 Kuwahara T, Yamayoshi S, Noda T, Kawaoka Y. G Protein Pathway Suppressor 1 Promotes Influenza Virus Polymerase Activity by Activating the NF-κB Signaling Pathway. Mbio. 10. PMID 31848286 DOI: 10.1128/Mbio.02867-19  0.604
2019 Zhong G, Fan S, Hatta M, Nakatsu S, Walters KB, Lopes TJS, Wang JI, Ozawa M, Karasin A, Li Y, Tong S, Donis RO, Neumann G, Kawaoka Y. Mutations in the NA-like protein of bat influenza H18N11 virus enhance virus replication in mammalian cells, mice, and ferrets. Journal of Virology. PMID 31801857 DOI: 10.1128/Jvi.01416-19  0.664
2019 Imai M, Yamashita M, Sakai-Tagawa Y, Iwatsuki-Horimoto K, Kiso M, Murakami J, Yasuhara A, Takada K, Ito M, Nakajima N, Takahashi K, Lopes TJS, Dutta J, Khan Z, Kriti D, ... ... Kawaoka Y, et al. Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets. Nature Microbiology. PMID 31768027 DOI: 10.1038/S41564-019-0609-0  0.568
2019 Kiso M, Yamayoshi S, Furusawa Y, Imai M, Kawaoka Y. Treatment of Highly Pathogenic H7N9 Virus-Infected Mice with Baloxavir Marboxil. Viruses. 11: 1066. PMID 31731678 DOI: 10.3390/V11111066  0.594
2019 Sakai-Tagawa Y, Yamayoshi S, Kawaoka Y. Sensitivity of Commercially Available Influenza Rapid Diagnostic Tests in the 2018-2019 Influenza Season. Frontiers in Microbiology. 10: 2342. PMID 31681207 DOI: 10.3389/Fmicb.2019.02342  0.625
2019 Matsuzawa Y, Iwatsuki-Horimoto K, Nishimoto Y, Abe Y, Fukuyama S, Hamabata T, Okuda M, Go Y, Watanabe T, Imai M, Arai Y, Fouchier RAM, Yamayoshi S, Kawaoka Y. Antigenic Change in Human Influenza A(H2N2) Viruses Detected by Using Human Plasma from Aged and Younger Adult Individuals. Viruses. 11. PMID 31652870 DOI: 10.3390/V11110978  0.618
2019 Wu L, Mitake H, Kiso M, Ito M, Iwatsuki-Hirimoto K, Yamayoshi S, Lopes TJS, Feng H, Sumiyoshi R, Shibata A, Osaka H, Imai M, Watanabe T, Kawaoka Y. Characterization of H7N9 avian influenza viruses isolated from duck meat products. Transboundary and Emerging Diseases. PMID 31650680 DOI: 10.1111/Tbed.13398  0.677
2019 Feldmann F, Kobasa D, Embury-Hyatt C, Grolla A, Taylor T, Kiso M, Kakugawa S, Gren J, Jones SM, Kawaoka Y, Feldmann H. Oseltamivir Is Effective against 1918 Influenza Virus Infection of Macaques but Vulnerable to Escape. Mbio. 10. PMID 31641086 DOI: 10.1128/Mbio.02059-19  0.65
2019 Feng H, Nakajima N, Wu L, Yamashita M, Lopes TJS, Tsuji M, Hasegawa H, Watanabe T, Kawaoka Y. A Glycolipid Adjuvant, 7DW8-5, Enhances the Protective Immune Response to the Current Split Influenza Vaccine in Mice. Frontiers in Microbiology. 10: 2157. PMID 31620111 DOI: 10.3389/Fmicb.2019.02157  0.422
2019 Mitchell HD, Eisfeld AJ, Stratton KG, Heller NC, Bramer LM, Wen J, McDermott JE, Gralinski LE, Sims AC, Le MQ, Baric RS, Kawaoka Y, Waters KM. The Role of EGFR in Influenza Pathogenicity: Multiple Network-Based Approaches to Identify a Key Regulator of Non-lethal Infections. Frontiers in Cell and Developmental Biology. 7: 200. PMID 31616667 DOI: 10.3389/Fcell.2019.00200  0.604
2019 Furusawa Y, Yamada S, da Silva Lopes TJ, Dutta J, Khan Z, Kriti D, van Bakel H, Kawaoka Y. Influenza Virus Polymerase Mutation Stabilizes a Foreign Gene Inserted into the Virus Genome by Enhancing the Transcription/Replication Efficiency of the Modified Segment. Mbio. 10. PMID 31575766 DOI: 10.1128/Mbio.01794-19  0.587
2019 Feng H, Yamashita M, Wu L, Jose da Silva Lopes T, Watanabe T, Kawaoka Y. Food Additives as Novel Influenza Vaccine Adjuvants. Vaccines. 7. PMID 31554190 DOI: 10.3390/Vaccines7040127  0.48
2019 Yamada S, Yasuhara A, Kawaoka Y. Soluble Recombinant Hemagglutinin Protein of H1N1pdm09 Influenza Virus Elicits Cross-Protection Against a Lethal H5N1 Challenge in Mice. Frontiers in Microbiology. 10: 2031. PMID 31551968 DOI: 10.3389/Fmicb.2019.02031  0.564
2019 Mukai Y, Tomita Y, Kryukov K, Nakagawa S, Ozawa M, Matsui T, Tomonaga K, Imanishi T, Kawaoka Y, Watanabe T, Horie M. Identification of a distinct lineage of aviadenovirus from crane feces. Virus Genes. PMID 31549291 DOI: 10.1007/S11262-019-01703-W  0.522
2019 Watanabe T, Suzuki N, Tomonaga K, Sawa H, Matsuura Y, Kawaguchi Y, Takahashi H, Nagasaki K, Kawaoka Y. Neo-virology: The raison d'etre of viruses. Virus Research. 197751. PMID 31520652 DOI: 10.1016/J.Virusres.2019.197751  0.541
2019 Ujie M, Takada K, Kiso M, Sakai-Tagawa Y, Ito M, Nakamura K, Watanabe S, Imai M, Kawaoka Y. Long-term culture of human lung adenocarcinoma A549 cells enhances the replication of human influenza A viruses. The Journal of General Virology. PMID 31424377 DOI: 10.1099/Jgv.0.001314  0.431
2019 Arikata M, Itoh Y, Shichinohe S, Nakayama M, Ishigaki H, Kinoshita T, Le MQ, Kawaoka Y, Ogasawara K, Shimizu T. Efficacy of clarithromycin against H5N1 and H7N9 avian influenza a virus infection in cynomolgus monkeys Antiviral Research. 171: 104591. PMID 31421167 DOI: 10.1016/J.Antiviral.2019.104591  0.656
2019 DiPiazza AT, Fan S, Rattan A, DeDiego ML, Chaves F, Neumann G, Kawaoka Y, Sant AJ. A Novel Vaccine Strategy to Overcome Poor Immunogenicity of Avian Influenza Vaccines through Mobilization of Memory CD4 T Cells Established by Seasonal Influenza. Journal of Immunology (Baltimore, Md. : 1950). PMID 31399519 DOI: 10.4049/Jimmunol.1900819  0.451
2019 Halfmann PJ, Eisfeld AJ, Watanabe T, Maemura T, Yamashita M, Fukuyama S, Armbrust T, Rozich I, N'jai A, Neumann G, Kawaoka Y, Sahr F. Serological analysis of Ebola virus survivors and close contacts in Sierra Leone: A cross-sectional study. Plos Neglected Tropical Diseases. 13: e0007654. PMID 31369554 DOI: 10.1371/Journal.Pntd.0007654  0.529
2019 Kingstad-Bakke BA, Chandrasekar SS, Phanse Y, Ross KA, Hatta M, Suresh M, Kawaoka Y, Osorio JE, Narasimhan B, Talaat AM. Effective mosaic-based nanovaccines against avian influenza in poultry. Vaccine. PMID 31300285 DOI: 10.1016/J.Vaccine.2019.06.077  0.572
2019 Zhong G, Fan S, Lopes TJS, Le MQ, van Bakel H, Dutta J, Smith GJD, Jayakumar J, Nguyen HLK, Hoang PVM, Halfmann P, Hatta M, Su YCF, Neumann G, Kawaoka Y. Isolation of Highly Pathogenic H5N1 Influenza Viruses in 2009-2013 in Vietnam. Frontiers in Microbiology. 10: 1411. PMID 31293548 DOI: 10.3389/Fmicb.2019.01411  0.647
2019 Moser MJ, Hatta Y, Gabaglia C, Sanchez A, Dias P, Sarawar S, Kawaoka Y, Hatta M, Neumann G, Bilsel P. Single-replication BM2SR vaccine provides sterilizing immunity and cross-lineage influenza B virus protection in mice. Vaccine. PMID 31280945 DOI: 10.1016/J.Vaccine.2019.06.043  0.574
2019 Nemoto M, Yamayoshi S, Bannai H, Tsujimura K, Kokado H, Kawaoka Y, Yamanaka T. A single amino acid change in hemagglutinin reduces the cross-reactivity of antiserum against an equine influenza vaccine strain. Archives of Virology. 164: 2355-2358. PMID 31227892 DOI: 10.1007/S00705-019-04328-4  0.499
2019 Liang L, Jiang L, Li J, Zhao Q, Wang J, He X, Huang S, Wang Q, Zhao Y, Wang G, Sun N, Deng G, Shi J, Tian G, Zeng X, ... ... Kawaoka Y, et al. Low Polymerase Activity Attributed to PA Drives the Acquisition of the PB2 E627K Mutation of H7N9 Avian Influenza Virus in Mammals. Mbio. 10. PMID 31213560 DOI: 10.1128/Mbio.01162-19  0.587
2019 Davis CW, Jackson KJL, McElroy AK, Halfmann P, Huang J, Chennareddy C, Piper AE, Leung Y, Albariño CG, Crozier I, Ellebedy AH, Sidney J, Sette A, Yu T, Nielsen SCA, ... ... Kawaoka Y, et al. Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection. Cell. PMID 31104840 DOI: 10.1016/J.Cell.2019.04.036  0.422
2019 Takada K, Kawakami C, Fan S, Chiba S, Zhong G, Gu C, Shimizu K, Takasaki S, Sakai-Tagawa Y, Lopes TJS, Dutta J, Khan Z, Kriti D, van Bakel H, Yamada S, ... ... Kawaoka Y, et al. A humanized MDCK cell line for the efficient isolation and propagation of human influenza viruses. Nature Microbiology. PMID 31036910 DOI: 10.1038/S41564-019-0433-6  0.614
2019 Okuda M, Yamayoshi S, Uraki R, Ito M, Hamabata T, Kawaoka Y. Subclade 2.2.1-Specific Human Monoclonal Antibodies That Recognize an Epitope in Antigenic Site A of Influenza A(H5) Virus HA Detected between 2015 and 2018 Viruses. 11: 321. PMID 30987023 DOI: 10.3390/V11040321  0.555
2019 Oishi K, Yamayoshi S, Kawaoka Y. Identification of Amino Acid Residues in Influenza A Virus PA-X That Contribute to Enhanced Shutoff Activity. Frontiers in Microbiology. 10: 432. PMID 30894843 DOI: 10.3389/Fmicb.2019.00432  0.46
2019 Yasuhara A, Yamayoshi S, Kiso M, Sakai-Tagawa Y, Koga M, Adachi E, Kikuchi T, Wang IH, Yamada S, Kawaoka Y. Antigenic drift originating from changes to the lateral surface of the neuraminidase head of influenza A virus. Nature Microbiology. PMID 30886361 DOI: 10.1038/S41564-019-0401-1  0.443
2019 Kyle JE, Burnum-Johnson KE, Wendler JP, Eisfeld AJ, Halfmann PJ, Watanabe T, Sahr F, Smith RD, Kawaoka Y, Waters KM, Metz TO. Plasma lipidome reveals critical illness and recovery from human Ebola virus disease. Proceedings of the National Academy of Sciences of the United States of America. 116: 3919-3928. PMID 30808769 DOI: 10.1073/Pnas.1815356116  0.401
2019 Kawakami C, Yamayoshi S, Akimoto M, Nakamura K, Miura H, Fujisaki S, Pattinson DJ, Shimizu K, Ozawa H, Momoki T, Saikusa M, Yasuhara A, Usuku S, Okubo I, Toyozawa T, ... ... Kawaoka Y, et al. Genetic and antigenic characterisation of influenza A(H3N2) viruses isolated in Yokohama during the 2016/17 and 2017/18 influenza seasons. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. 24. PMID 30755292 DOI: 10.2807/1560-7917.Es.2019.24.6.1800467  0.647
2019 Ito M, Yamayoshi S, Murakami K, Saito K, Motojima A, Nakaishi K, Kawaoka Y. Characterization of Mouse Monoclonal Antibodies Against the HA of A(H7N9) Influenza Virus. Viruses. 11: 149. PMID 30754701 DOI: 10.3390/V11020149  0.634
2019 Yamayoshi S, Kawaoka Y. Host protein mimics viral protein to hinder infection by Ebola virus. Nature. 566: 190-191. PMID 30737499 DOI: 10.1038/D41586-019-00182-1  0.519
2019 Feng H, Yamashita M, da Silva Lopes TJ, Watanabe T, Kawaoka Y. Injectable Excipients as Novel Influenza Vaccine Adjuvants. Frontiers in Microbiology. 10: 19. PMID 30733711 DOI: 10.3389/Fmicb.2019.00019  0.49
2019 Williamson L, Flyak AI, Kose N, Bombardi R, Branchizio A, Reddy S, Davidson E, Doranz B, Fusco ML, Saphire EO, Halfmann PJ, Kawaoka Y, Piper AE, Glass PJ, Crowe JE. Early human B cell response to Ebola virus in four U.S. survivors of infection. Journal of Virology. PMID 30728263 DOI: 10.1128/Jvi.01439-18  0.467
2019 Neumann G, Kawaoka Y. Predicting the Next Influenza Pandemics The Journal of Infectious Diseases. 219. PMID 30715371 DOI: 10.1093/Infdis/Jiz040  0.63
2019 Tabata KV, Minagawa Y, Kawaguchi Y, Ono M, Moriizumi Y, Yamayoshi S, Fujioka Y, Ohba Y, Kawaoka Y, Noji H. Antibody-free digital influenza virus counting based on neuraminidase activity Scientific Reports. 9: 1067-1067. PMID 30705374 DOI: 10.1038/S41598-018-37994-6  0.567
2019 Yamayoshi S, Kawaoka Y. Current and future influenza vaccines. Nature Medicine. 25: 212-220. PMID 30692696 DOI: 10.1038/S41591-018-0340-Z  0.569
2019 Nanbo A, Kawaoka Y. Molecular Mechanism of Externalization of Phosphatidylserine on the Surface of Ebola Virus Particles. Dna and Cell Biology. 38: 115-120. PMID 30615471 DOI: 10.1089/Dna.2018.4485  0.606
2019 Eiden J, Volckaert B, Rudenko O, Ellis R, Aitchison R, Herber R, Belshe R, Greenberg H, Coelingh K, Kawaoka Y, Neumann G, Bilsel P. 2748. Single Intranasal (IN) Dose of M2SR (M2-Deficient Single Replication) Live Influenza Vaccine Protects Adults Against Subsequent Challenge with a Substantially Drifted H3N2 Strain Open Forum Infectious Diseases. 6. DOI: 10.1093/Ofid/Ofz360.2425  0.482
2018 Eisfeld AJ, Gasper DJ, Suresh M, Kawaoka Y. C57BL/6J and C57BL/6NJ Mice Are Differentially Susceptible to Inflammation-Associated Disease Caused by Influenza A Virus. Frontiers in Microbiology. 9: 3307. PMID 30713529 DOI: 10.3389/Fmicb.2018.03307  0.649
2018 Ackerman EE, Kawakami E, Katoh M, Watanabe T, Watanabe S, Tomita Y, Lopes TJ, Matsuoka Y, Kitano H, Shoemaker JE, Kawaoka Y. Network-Guided Discovery of Influenza Virus Replication Host Factors. Mbio. 9. PMID 30563907 DOI: 10.1128/Mbio.02002-18  0.512
2018 Gu C, Zeng X, Song Y, Li Y, Liu L, Kawaoka Y, Zhao D, Chen H. Glycosylation and an amino acid insertion in the head of hemagglutinin independently affect the antigenic properties of H5N1 avian influenza viruses. Science China. Life Sciences. PMID 30515728 DOI: 10.1007/S11427-018-9439-0  0.592
2018 Yasuhara A, Yamayoshi S, Ito M, Kiso M, Yamada S, Kawaoka Y. Isolation and Characterization of Human Monoclonal Antibodies That Recognize the Influenza A(H1N1)pdm09 Virus Hemagglutinin Receptor-Binding Site and Rarely Yield Escape Mutant Viruses. Frontiers in Microbiology. 9: 2660. PMID 30443246 DOI: 10.3389/Fmicb.2018.02660  0.622
2018 Bedi S, Noda T, Kawaoka Y, Ono A. A Defect in Influenza A Virus Particle Assembly Specific to Primary Human Macrophages. Mbio. 9. PMID 30352935 DOI: 10.1128/Mbio.01916-18  0.514
2018 Wu NC, Yamayoshi S, Ito M, Uraki R, Kawaoka Y, Wilson IA. Recurring and Adaptable Binding Motifs in Broadly Neutralizing Antibodies to Influenza Virus Are Encoded on the D3-9 Segment of the Ig Gene. Cell Host & Microbe. 24: 569-578.e4. PMID 30308159 DOI: 10.1016/J.Chom.2018.09.010  0.531
2018 Yamayoshi S, Yasuhara A, Ito M, Uraki R, Kawaoka Y. Differences in the ease with which mutant viruses escape from human monoclonal antibodies against the HA stem of influenza A virus. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 108: 105-111. PMID 30292135 DOI: 10.1016/J.Jcv.2018.09.016  0.627
2018 Chiba S, Hill-Batorski L, Neumann G, Kawaoka Y. The Cellular DExD/H-Box RNA Helicase UAP56 Co-localizes With the Influenza A Virus NS1 Protein Frontiers in Microbiology. 9: 2192. PMID 30258431 DOI: 10.3389/Fmicb.2018.02192  0.548
2018 Hatta M, Zhong G, Chiba S, Lopes TJS, Neumann G, Kawaoka Y. Effectiveness of Whole, Inactivated, Low Pathogenicity Influenza A(H7N9) Vaccine against Antigenically Distinct, Highly Pathogenic H7N9 Virus. Emerging Infectious Diseases. 24: 1910-1913. PMID 30226171 DOI: 10.3201/Eid2410.180403  0.618
2018 Neumann G, Fan S, Kawaoka Y. Selection of Antigenically Advanced Variants of Influenza Viruses. Methods in Molecular Biology (Clifton, N.J.). 1836: 461-486. PMID 30151587 DOI: 10.1007/978-1-4939-8678-1_22  0.665
2018 Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, ... ... Kawaoka Y, et al. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 174: 938-952.e13. PMID 30096313 DOI: 10.1016/J.Cell.2018.07.033  0.462
2018 Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, ... ... Kawaoka Y, et al. A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus. Cell Host & Microbe. 24: 221-233.e5. PMID 30092199 DOI: 10.1016/J.Chom.2018.07.009  0.42
2018 Furusawa Y, Yamada S, Kawaoka Y. Host Factor Nucleoporin 93 Is Involved in the Nuclear Export of Influenza Virus RNA. Frontiers in Microbiology. 9: 1675. PMID 30087672 DOI: 10.3389/Fmicb.2018.01675  0.614
2018 Halfmann P, Hill-Batorski L, Kawaoka Y. The Induction of IL-1β Secretion Through the NLRP3 Inflammasome During Ebola Virus Infection. The Journal of Infectious Diseases. 218. PMID 30060221 DOI: 10.1093/Infdis/Jiy433  0.363
2018 Oishi K, Yamayoshi S, Kozuka-Hata H, Oyama M, Kawaoka Y. N-Terminal Acetylation by NatB Is Required for the Shutoff Activity of Influenza A Virus PA-X. Cell Reports. 24: 851-860. PMID 30044982 DOI: 10.1016/J.Celrep.2018.06.078  0.443
2018 Sammaibashi S, Yamayoshi S, Kawaoka Y. Strain-Specific Contribution of Eukaryotic Elongation Factor 1 Gamma to the Translation of Influenza A Virus Proteins. Frontiers in Microbiology. 9: 1446. PMID 30008712 DOI: 10.3389/Fmicb.2018.01446  0.615
2018 Hatta Y, Boltz D, Sarawar S, Kawaoka Y, Neumann G, Bilsel P. Novel influenza vaccine M2SR protects against drifted H1N1 and H3N2 influenza virus challenge in ferrets with pre-existing immunity. Vaccine. 36: 5097-5103. PMID 30007825 DOI: 10.1016/J.Vaccine.2018.06.053  0.604
2018 Iwatsuki-Horimoto K, Shi J, Wang X, Sakai-Tagawa Y, Ito M, Murakami K, da Silva Lopes TJ, Nakaishi K, Yamayoshi S, Watabe S, Chen H, Kawaoka Y. Development of an Influenza Rapid Diagnostic Kit Specific for the H7 Subtype. Frontiers in Microbiology. 9: 1346. PMID 29988537 DOI: 10.3389/Fmicb.2018.01346  0.65
2018 Ueki H, Wang I, Fukuyama S, Katsura H, Lopes TJdS, Neumann G, Kawaoka Y. In vivo imaging of the pathophysiological changes and neutrophil dynamics in influenza virus-infected mouse lungs. Proceedings of the National Academy of Sciences of the United States of America. 115: 201806265. PMID 29941581 DOI: 10.1073/Pnas.1806265115  0.532
2018 Imai H, Dinis JM, Zhong G, Moncla LH, Lopes TJS, McBride R, Thompson AJ, Peng W, Le MTQ, Hanson A, Lauck M, Sakai-Tagawa Y, Yamada S, Eggenberger J, O'Connor DH, ... ... Kawaoka Y, et al. Diversity of Influenza A(H5N1) Viruses in Infected Humans, Northern Vietnam, 2004-2010. Emerging Infectious Diseases. 24: 1128-1238. PMID 29912683 DOI: 10.3201/Eid2407.171441  0.652
2018 Iwatsuki-Horimoto K, Nakajima N, Kiso M, Takahashi K, Ito M, Inoue T, Horiuchi M, Okahara N, Sasaki E, Hasegawa H, Kawaoka Y. The Marmoset as an Animal Model of Influenza: Infection With A(H1N1)pdm09 and Highly Pathogenic A(H5N1) Viruses via the Conventional or Tracheal Spray Route. Frontiers in Microbiology. 9: 844. PMID 29867791 DOI: 10.3389/Fmicb.2018.00844  0.663
2018 Kuwahara T, Takashita E, Fujisaki S, Shirakura M, Nakamura K, Kishida N, Takahashi H, Suzuki N, Kawaoka Y, Watanabe S, Odagiri T. Isolation of egg-adapted influenza A(H3N2) virus without amino acid substitutions in the antigenic sites of its hemagglutinin. Japanese Journal of Infectious Diseases. PMID 29709975 DOI: 10.7883/Yoken.Jjid.2017.551  0.625
2018 Soni P, Yasuhara A, Takenaga T, Iwatsuki-Horimoto K, Uraki R, Ito M, Sasaki T, Ikuta K, Yamayoshi S, Kawaoka Y. Evaluation of the fusion partner cell line SPYMEG for obtaining human monoclonal antibodies against influenza B virus. The Journal of Veterinary Medical Science. PMID 29669959 DOI: 10.1292/Jvms.18-0146  0.546
2018 Fujihira H, Usami K, Matsuno K, Takeuchi H, Denda-Nagai K, Furukawa J, Shinohara Y, Takada A, Kawaoka Y, Irimura T. A Critical Domain of Ebolavirus Envelope Glycoprotein Determines Glycoform and Infectivity. Scientific Reports. 8: 5495-5495. PMID 29615747 DOI: 10.1038/S41598-018-23357-8  0.344
2018 Watanabe T, Iwatsuki-Horimoto K, Kiso M, Nakajima N, Takahashi K, Jose da Silva Lopes T, Ito M, Fukuyama S, Hasegawa H, Kawaoka Y. Experimental infection of Cynomolgus Macaques with highly pathogenic H5N1 influenza virus through the aerosol route. Scientific Reports. 8: 4801. PMID 29556081 DOI: 10.1038/S41598-018-23022-0  0.62
2018 Hatakeyama D, Shoji M, Yamayoshi S, Yoh R, Ohmi N, Takenaka S, Saitoh A, Arakaki Y, Masuda A, Komatsu T, Nagano R, Nakano M, Noda T, Kawaoka Y, Kuzuhara T. Influenza A virus nucleoprotein is acetylated by histone acetyltransferases, PCAF and GCN5. The Journal of Biological Chemistry. PMID 29555684 DOI: 10.1074/Jbc.Ra117.001683  0.55
2018 Yamayoshi S, Kiso M, Yasuhara A, Ito M, Shu Y, Kawaoka Y. Enhanced Replication of Highly Pathogenic Influenza A(H7N9) Virus in Humans. Emerging Infectious Diseases. 24: 746-750. PMID 29553313 DOI: 10.3201/Eid2404.171509  0.656
2018 Matsui K, Ozawa M, Kiso M, Yamashita M, Maekawa T, Kubota M, Sugano S, Kawaoka Y. Stimulation of alpha2-adrenergic receptors impairs influenza virus infection. Scientific Reports. 8: 4631. PMID 29545586 DOI: 10.1038/S41598-018-22927-0  0.626
2018 Maemura T, Fukuyama S, Sugita Y, Lopes TJS, Nakao T, Noda T, Kawaoka Y. Lung-Derived Exosomal miR-483-3p Regulates the Innate Immune Response to Influenza Virus Infection. The Journal of Infectious Diseases. 217: 1372-1382. PMID 29373693 DOI: 10.1093/Infdis/Jiy035  0.446
2018 Menachery VD, Schäfer A, Burnum-Johnson KE, Mitchell HD, Eisfeld AJ, Walters KB, Nicora CD, Purvine SO, Casey CP, Monroe ME, Weitz KK, Stratton KG, Webb-Robertson BM, Gralinski LE, Metz TO, ... ... Kawaoka Y, et al. MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339515 DOI: 10.1073/Pnas.1706928115  0.603
2018 Nanbo A, Maruyama J, Imai M, Ujie M, Fujioka Y, Nishide S, Takada A, Ohba Y, Kawaoka Y. Ebola virus requires a host scramblase for externalization of phosphatidylserine on the surface of viral particles. Plos Pathogens. 14. PMID 29338048 DOI: 10.1371/Journal.Ppat.1006848  0.394
2018 Oishi K, Yamayoshi S, Kawaoka Y. Identification of novel amino acid residues of influenza virus PA-X that are important for PA-X shutoff activity by using yeast. Virology. 516: 71-75. PMID 29331676 DOI: 10.1016/J.Virol.2018.01.004  0.335
2018 Nakatsu S, Murakami S, Shindo K, Horimoto T, Sagara H, Noda T, Kawaoka Y. Influenza C and D Viruses Package Eight Organized Ribonucleoprotein Complexes Journal of Virology. 92. PMID 29321324 DOI: 10.1128/Jvi.02084-17  0.517
2018 Noda T, Murakami S, Nakatsu S, Imai H, Muramoto Y, Shindo K, Sagara H, Kawaoka Y. Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging. Nature Communications. 9: 54-54. PMID 29302061 DOI: 10.1038/S41467-017-02517-W  0.504
2018 Hatta M, Zhong G, Gao Y, Nakajima N, Fan S, Chiba S, Deering KM, Ito M, Imai M, Kiso M, Nakatsu S, Lopes TJ, Thompson AJ, McBride R, Suarez DL, ... ... Kawaoka Y, et al. Characterization of a Feline Influenza A(H7N2) Virus. Emerging Infectious Diseases. 24: 75-86. PMID 29260686 DOI: 10.3201/Eid2401.171240  0.666
2018 Zhong G, Le MQ, Lopes TJS, Halfmann P, Hatta M, Fan S, Neumann G, Kawaoka Y. Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virulence. Journal of Virology. 92. PMID 29212927 DOI: 10.1128/Jvi.01557-17  0.665
2018 Wu NC, Yamayoshi S, Ito M, Uraki R, Kawaoka Y, Wilson IA. The D3-9 gene segment encodes for recurring and adaptable binding motifs in broadly neutralizing antibodies to influenza virus Cell Host & Microbe. DOI: 10.2210/Pdb6E3H/Pdb  0.544
2018 Sugita Y, Matsunami H, Kawaoka Y, Noda T, Wolf M. Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex at 3.6 angstrom resolution. Nature. 563: 137-140. DOI: 10.2210/Pdb5Z9W/Pdb  0.401
2018 Eiden J, Gordon G, Fierro C, Belshe R, Greenberg H, Hoft D, Hatta Y, Imboden M, Moser M, Herber R, Boltz D, Tary-Lehmann M, Kawaoka Y, Neumann G, Radspinner P, et al. 1970. Phase 1 Clinical Trial of Intranasal Immunization with M2-Deficient, Single Replication, Live Influenza Vaccine (M2SR): Safety and Immune Response in Adults Open Forum Infectious Diseases. 5. DOI: 10.1093/Ofid/Ofy210.1626  0.369
2018 Becker S, Feldmann H, Geisbert T, Kawaoka Y. Marburg and Ebola Viruses – Marking 50 Years Since Their Discovery The Journal of Infectious Diseases. 218: Si-Si. DOI: 10.1093/Infdis/Jiy674  0.455
2018 Wang M, Fukuyama S, Kawaoka Y, Shoemaker JE. Predicting host immune cell dynamics using tissue gene expression Ifac-Papersonline. 51: 5-6. DOI: 10.1016/J.Ifacol.2018.09.005  0.323
2017 Yasuhara A, Yamayoshi S, Soni P, Takenaga T, Kawakami C, Takashita E, Sakai-Tagawa Y, Uraki R, Ito M, Iwatsuki-Horimoto K, Sasaki T, Ikuta K, Yamada S, Kawaoka Y. Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies. Scientific Reports. 7: 17735. PMID 29255273 DOI: 10.1038/S41598-017-17986-8  0.596
2017 Yamayoshi S, Ito M, Uraki R, Sasaki T, Ikuta K, Kawaoka Y. Human protective monoclonal antibodies against the HA stem of group 2 HAs derived from an H3N2 virus-infected human. Journal of Infection. 76: 177-185. PMID 29248585 DOI: 10.1016/J.Jinf.2017.12.004  0.56
2017 Iwatsuki-Horimoto K, Nakajima N, Ichiko Y, Sakai-Tagawa Y, Noda T, Hasegawa H, Kawaoka Y. Syrian Hamster as an Animal Model for the Study of Human Influenza Virus Infection. Journal of Virology. 92. PMID 29212926 DOI: 10.1128/Jvi.01693-17  0.69
2017 Kiso M, Lopes TJS, Yamayoshi S, Ito M, Yamashita M, Nakajima N, Hasegawa H, Neumann G, Kawaoka Y. Combination Therapy with Neuraminidase and Polymerase Inhibitors in Nude Mice Infected with Influenza Virus. The Journal of Infectious Diseases. PMID 29186472 DOI: 10.1093/Infdis/Jix606  0.546
2017 Eisfeld AJ, Halfmann PJ, Wendler JP, Kyle JE, Burnum-Johnson KE, Peralta Z, Maemura T, Walters KB, Watanabe T, Fukuyama S, Yamashita M, Jacobs JM, Kim YM, Casey CP, Stratton KG, ... ... Kawaoka Y, et al. Multi-platform 'Omics Analysis of Human Ebola Virus Disease Pathogenesis. Cell Host & Microbe. PMID 29154144 DOI: 10.1016/J.Chom.2017.10.011  0.534
2017 Sakai-Tagawa Y, Yamayoshi S, Kawakami C, Le MQ, Uchida Y, Saito T, Nidom CA, Humaira I, Toohey-Kurth K, Arafa AS, Liu MT, Shu Y, Kawaoka Y. Reactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan. Scientific Reports. 7: 14483. PMID 29101372 DOI: 10.1038/S41598-017-14536-0  0.602
2017 Watanabe T, Imai M, Kawaoka Y. NS1 is the fluid for "flu-transmission". Proceedings of the National Academy of Sciences of the United States of America. 114: 11012-11014. PMID 29073013 DOI: 10.1073/Pnas.1715239114  0.626
2017 Imai M, Watanabe T, Kiso M, Nakajima N, Yamayoshi S, Iwatsuki-Horimoto K, Hatta M, Yamada S, Ito M, Sakai-Tagawa Y, Shirakura M, Takashita E, Fujisaki S, McBride R, Thompson AJ, ... ... Kawaoka Y, et al. A Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected via Respiratory Droplets. Cell Host & Microbe. PMID 29056430 DOI: 10.1016/J.Chom.2017.09.008  0.675
2017 Kiso M, Iwatsuki-Horimoto K, Yamayoshi S, Uraki R, Ito M, Nakajima N, Yamada S, Imai M, Kawakami E, Tomita Y, Fukuyama S, Itoh Y, Ogasawara K, Lopes TJS, Watanabe T, ... ... Kawaoka Y, et al. Emergence of Oseltamivir-Resistant H7N9 Influenza Viruses in Immunosuppressed Cynomolgus Macaques. The Journal of Infectious Diseases. 216: 582-593. PMID 28931216 DOI: 10.1093/Infdis/Jix296  0.632
2017 Eisfeld AJ, Kawaoka Y. Calculated risk: a new single-nucleotide polymorphism linked to severe influenza disease. Nature Medicine. 23: 911-912. PMID 28777788 DOI: 10.1038/Nm.4383  0.496
2017 Hatta Y, Boltz D, Sarawar S, Kawaoka Y, Neumann G, Bilsel P. M2SR, a novel live influenza vaccine, protects mice and ferrets against highly pathogenic avian influenza. Vaccine. 35: 4177-4183. PMID 28668565 DOI: 10.1016/J.Vaccine.2017.06.039  0.636
2017 Yamayoshi S, Kawaoka Y. Ebolavirus’s Foibles Cell. 169: 773-775. PMID 28525748 DOI: 10.1016/J.Cell.2017.05.008  0.344
2017 Yamayoshi S, Uraki R, Ito M, Kiso M, Nakatsu S, Yasuhara A, Oishi K, Sasaki T, Ikuta K, Kawaoka Y. A Broadly Reactive Human Anti-hemagglutinin Stem Monoclonal Antibody That Inhibits Influenza A Virus Particle Release. Ebiomedicine. PMID 28286060 DOI: 10.1016/J.Ebiom.2017.03.007  0.537
2017 Ui H, Yamayoshi S, Uraki R, Kiso M, Oishi K, Murakami S, Mimori S, Kawaoka Y. Evaluation of seasonal influenza vaccines for H1N1pdm09 and type B viruses based on a replication-incompetent PB2-KO virus. Vaccine. 35: 1892-1897. PMID 28285982 DOI: 10.1016/J.Vaccine.2017.02.041  0.633
2017 Nakayama M, Itoh Y, Shichinohe S, Nakabayashi R, Ishigaki H, Sakoda Y, Le QM, Kawaoka Y, Kida H, Ogasawara K. Potential risk of repeated nasal vaccination that induces allergic reaction with mucosal IgE and airway eosinophilic infiltration in cynomolgus macaques infected with H5N1 highly pathogenic avian influenza virus Vaccine. 35: 1008-1017. PMID 28109707 DOI: 10.1016/J.Vaccine.2017.01.008  0.536
2017 Zhao D, Liang L, Wang S, Nakao T, Li Y, Liu L, Guan Y, Fukuyama S, Bu Z, Kawaoka Y, Chen H. Glycosylation of the HA protein of H5N1 virus increases its virulence in mice by exacerbating the host immune response. Journal of Virology. PMID 28100622 DOI: 10.1128/Jvi.02215-16  0.656
2017 Burnum-Johnson KE, Kyle JE, Eisfeld AJ, Casey CP, Stratton KG, Gonzalez JF, Habyarimana F, Negretti NM, Sims AC, Chauhan S, Thackray LB, Halfmann PJ, Walters KB, Kim YM, Zink EM, ... ... Kawaoka Y, et al. MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling. The Analyst. PMID 28091625 DOI: 10.1039/C6An02486F  0.449
2016 Watanabe T, Kawaoka Y. Neo-Virology: the raison d'etre of viruses. Uirusu. 66: 155-162. PMID 29081467 DOI: 10.2222/Jsv.66.155  0.504
2016 Watanabe T, Kawaoka Y. Control of Ebola hemorrhagic fever: vaccine development and our Ebola project in Sierra Leone. Uirusu. 66: 53-62. PMID 28484179 DOI: 10.2222/Jsv.66.53  0.566
2016 Gasper DJ, Neldner B, Plisch EH, Rustom H, Carrow E, Imai H, Kawaoka Y, Suresh M. Effective Respiratory CD8 T-Cell Immunity to Influenza Virus Induced by Intranasal Carbomer-Lecithin-Adjuvanted Non-replicating Vaccines Plos Pathogens. 12. PMID 27997610 DOI: 10.1371/Journal.Ppat.1006064  0.418
2016 Ping J, Lopes TJ, Neumann G, Kawaoka Y. Development of high-yield influenza B virus vaccine viruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 27930325 DOI: 10.1073/Pnas.1616530113  0.665
2016 Arafa AS, Yamada S, Imai M, Watanabe T, Yamayoshi S, Iwatsuki-Horimoto K, Kiso M, Sakai-Tagawa Y, Ito M, Imamura T, Nakajima N, Takahashi K, Zhao D, Oishi K, Yasuhara A, ... ... Kawaoka Y, et al. Risk assessment of recent Egyptian H5N1 influenza viruses. Scientific Reports. 6: 38388. PMID 27922116 DOI: 10.1038/Srep38388  0.65
2016 Iwatsuki-Horimoto K, Nakajima N, Shibata M, Takahashi K, Sato Y, Kiso M, Yamayoshi S, Ito M, Enya S, Otake M, Kangawa A, da Silva Lopes TJ, Ito H, Hasegawa H, Kawaoka Y. Microminipigs as an animal model for influenza A virus infection. Journal of Virology. PMID 27807225 DOI: 10.1128/Jvi.01716-16  0.63
2016 Miyauchi K, Sugimoto-Ishige A, Harada Y, Adachi Y, Usami Y, Kaji T, Inoue K, Hasegawa H, Watanabe T, Hijikata A, Fukuyama S, Maemura T, Okada-Hatakeyama M, Ohara O, Kawaoka Y, et al. Protective neutralizing influenza antibody response in the absence of T follicular helper cells. Nature Immunology. PMID 27798619 DOI: 10.1038/Ni.3563  0.529
2016 Nakatsu S, Sagara H, Sakai-Tagawa Y, Sugaya N, Noda T, Kawaoka Y. Complete and Incomplete Genome Packaging of Influenza A and B Viruses Mbio. 7. PMID 27601575 DOI: 10.1128/Mbio.01248-16  0.554
2016 Sarawar S, Hatta Y, Watanabe S, Dias P, Neumann G, Kawaoka Y, Bilsel P. M2SR, a novel live single replication influenza virus vaccine, provides effective heterosubtypic protection in mice. Vaccine. PMID 27595896 DOI: 10.1016/J.Vaccine.2016.08.061  0.62
2016 Ando T, Yamayoshi S, Tomita Y, Watanabe S, Watanabe T, Kawaoka Y. The host protein CLUH participates in the subnuclear transport of influenza virus ribonucleoprotein complexes. Nature Microbiology. 1: 16062. PMID 27573102 DOI: 10.1038/Nmicrobiol.2016.62  0.458
2016 Li C, Hatta M, Burke DF, Ping J, Zhang Y, Ozawa M, Taft AS, Das SC, Hanson AP, Song J, Imai M, Wilker PR, Watanabe T, Watanabe S, Ito M, ... ... Kawaoka Y, et al. Selection of antigenically advanced variants of seasonal influenza viruses. Nature Microbiology. 1: 16058. PMID 27572841 DOI: 10.1038/Nmicrobiol.2016.58  0.631
2016 Chasman D, Walters KB, Lopes TJ, Eisfeld AJ, Kawaoka Y, Roy S. Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens. Plos Computational Biology. 12: e1005013. PMID 27403523 DOI: 10.1371/Journal.Pcbi.1005013  0.397
2016 Takashita E, Ejima M, Ogawa R, Fujisaki S, Neumann G, Furuta Y, Kawaoka Y, Tashiro M, Odagiri T. Antiviral susceptibility of influenza viruses isolated from patients pre- and post-administration of favipiravir. Antiviral Research. PMID 27321665 DOI: 10.1016/J.Antiviral.2016.06.007  0.627
2016 Westhoff Smith D, Hill-Batorski L, N'jai A, Eisfeld AJ, Neumann G, Halfmann P, Kawaoka Y. Ebola Virus Stability Under Hospital and Environmental Conditions. The Journal of Infectious Diseases. PMID 27279525 DOI: 10.1093/Infdis/Jiw167  0.454
2016 Tisoncik-Go J, Gasper DJ, Kyle JE, Eisfeld AJ, Selinger C, Hatta M, Morrison J, Korth MJ, Zink EM, Kim YM, Schepmoes AA, Nicora CD, Purvine SO, Weitz KK, Peng X, ... ... Kawaoka Y, et al. Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism. Cell Host & Microbe. 19: 254-66. PMID 26867183 DOI: 10.1016/J.Chom.2016.01.002  0.588
2016 Moncla LH, Zhong G, Nelson CW, Dinis JM, Mutschler J, Hughes AL, Watanabe T, Kawaoka Y, Friedrich TC. Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus. Cell Host & Microbe. 19: 169-80. PMID 26867176 DOI: 10.1016/J.Chom.2016.01.011  0.628
2016 Fujimoto Y, Ito H, Ono E, Kawaoka Y, Ito T. The Low-pH Resistance of Neuraminidase Is Essential for the Replication of Influenza A Virus in Duck Intestine following Infection via the Oral Route. Journal of Virology. 90: 4127-4132. PMID 26865722 DOI: 10.1128/JVI.03107-15  0.498
2016 Katsura H, Fukuyama S, Watanabe S, Ozawa M, Neumann G, Kawaoka Y. Amino acid changes in PB2 and HA affect the growth of a recombinant influenza virus expressing a fluorescent reporter protein. Scientific Reports. 6: 19933. PMID 26847414 DOI: 10.1038/Srep19933  0.614
2016 Pécheur EI, Borisevich V, Halfmann P, Morrey JD, Smee DF, Prichard M, Mire CE, Kawaoka Y, Geisbert TW, Polyak SJ. The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses. Journal of Virology. PMID 26739045 DOI: 10.1128/Jvi.02077-15  0.562
2016 Yang H, Chen Y, Qiao C, He X, Zhou H, Sun Y, Yin H, Meng S, Liu L, Zhang Q, Kong H, Gu C, Li C, Bu Z, Kawaoka Y, et al. Prevalence, genetics, and transmissibility in ferrets of Eurasian avian-like H1N1 swine influenza viruses. Proceedings of the National Academy of Sciences of the United States of America. 113: 392-7. PMID 26711995 DOI: 10.1073/Pnas.1522643113  0.656
2016 Fujimoto Y, Ito H, Ono E, Kawaoka Y, Ito T. The low-pH resistance of neuraminidase is essential for the replication of influenza A virus in duck intestine following infection via the oral route Journal of Virology. 90: 4127-4132. DOI: 10.1128/Jvi.03107-15  0.579
2016 Dye J, Chandran K, Kobinger G, Kawaoka Y, Zeitlin L, Ward A, Nykiforuk C, Aman J, Lai J, Saphire E. E-105 Antibodies against ebola virus Jaids Journal of Acquired Immune Deficiency Syndromes. 71: 58. DOI: 10.1097/01.Qai.0000479621.47644.67  0.479
2016 Sugita Y, Kawaoka Y, Noda T, Wolf M. Structure of the Ebola Virus Nucleocapsid Core by Single Particle Cryo-Electron Microscopy Microscopy and Microanalysis. 22: 66-67. DOI: 10.1017/S1431927616001185  0.406
2015 Hanson A, Imai M, Hatta M, McBride R, Imai H, Taft A, Zhong G, Watanabe T, Suzuki Y, Neumann G, Paulson JC, Kawaoka Y. Identification of Stabilizing Mutations in an H5 HA Influenza Virus Protein. Journal of Virology. PMID 26719265 DOI: 10.1128/Jvi.02790-15  0.6
2015 Zhao D, Fukuyama S, Sakai-Tagawa Y, Takashita E, Shoemaker JE, Kawaoka Y. C646, a novel p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, attenuates influenza A virus infection. Antimicrobial Agents and Chemotherapy. PMID 26711748 DOI: 10.1128/Aac.02055-15  0.591
2015 Forero A, Tisoncik-Go J, Watanabe T, Zhong G, Hatta M, Tchitchek N, Selinger C, Chang J, Barker K, Morrison J, Berndt JD, Moon RT, Josset L, Kawaoka Y, Katze MG. The 1918 PB2 protein enhances virulence through the disruption of inflammatory and Wnt-mediated signaling in mice. Journal of Virology. PMID 26656717 DOI: 10.1128/Jvi.02974-15  0.631
2015 Oda SI, Noda T, Wijesinghe KJ, Halfmann P, Bornholdt ZA, Abelson DM, Armbrust T, Stahelin RV, Kawaoka Y, Saphire EO. Crystal structure of Marburg virus VP40: matrix assembly and immunosuppression. Journal of Virology. PMID 26656687 DOI: 10.1128/Jvi.01597-15  0.52
2015 Yamayoshi S, Watanabe M, Goto H, Kawaoka Y. Identification of A Novel Viral Protein Expressed from the PB2 Segment of Influenza A Virus. Journal of Virology. PMID 26491155 DOI: 10.1128/Jvi.02175-15  0.641
2015 Watanabe T, Kawaoka Y. Influenza virus-host interactomes as a basis for antiviral drug development. Current Opinion in Virology. 14: 71-78. PMID 26364134 DOI: 10.1016/J.Coviro.2015.08.008  0.627
2015 Zhao D, Fukuyama S, Yamada S, Lopes TJ, Maemura T, Katsura H, Ozawa M, Watanabe S, Neumann G, Kawaoka Y. Molecular determinants of virulence and stability of a reporter-expressing H5N1 influenza A virus. Journal of Virology. PMID 26339046 DOI: 10.1128/Jvi.01886-15  0.686
2015 Ping J, Lopes TJ, Nidom CA, Ghedin E, Macken CA, Fitch A, Imai M, Maher EA, Neumann G, Kawaoka Y. Development of high-yield influenza A virus vaccine viruses. Nature Communications. 6: 8148. PMID 26334134 DOI: 10.1038/Ncomms9148  0.58
2015 Okumura A, Rasmussen AL, Halfmann P, Feldmann F, Yoshimura A, Feldmann H, Kawaoka Y, Harty RN, Katze MG. Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection. Journal of Virology. 89: 10399-406. PMID 26246577 DOI: 10.1128/Jvi.01736-15  0.542
2015 Okazaki T, Higuchi M, Takeda K, Iwatsuki-Horimoto K, Kiso M, Miyagishi M, Yanai H, Kato A, Yoneyama M, Fujita T, Taniguchi T, Kawaoka Y, Ichijo H, Gotoh Y. The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response. Science Signaling. 8: ra78. PMID 26243192 DOI: 10.1126/Scisignal.Aab1883  0.394
2015 Uraki R, Piao Z, Akeda Y, Iwatsuki-Horimoto K, Kiso M, Ozawa M, Oishi K, Kawaoka Y. A Bivalent Vaccine Based on a PB2-Knockout Influenza Virus Protects Mice From Secondary Pneumococcal Pneumonia. The Journal of Infectious Diseases. 212: 1939-48. PMID 26123562 DOI: 10.1093/Infdis/Jiv341  0.636
2015 Taft AS, Ozawa M, Fitch A, Depasse JV, Halfmann PJ, Hill-Batorski L, Hatta M, Friedrich TC, Lopes TJ, Maher EA, Ghedin E, Macken CA, Neumann G, Kawaoka Y. Identification of mammalian-adapting mutations in the polymerase complex of an avian H5N1 influenza virus. Nature Communications. 6: 7491. PMID 26082035 DOI: 10.1038/Ncomms8491  0.685
2015 Shoemaker JE, Fukuyama S, Eisfeld AJ, Zhao D, Kawakami E, Sakabe S, Maemura T, Gorai T, Katsura H, Muramoto Y, Watanabe S, Watanabe T, Fuji K, Matsuoka Y, Kitano H, ... Kawaoka Y, et al. An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation. Plos Pathogens. 11: e1004856. PMID 26046528 DOI: 10.1371/Journal.Ppat.1004856  0.575
2015 Oishi K, Yamayoshi S, Kawaoka Y. Mapping of a Region of the PA-X Protein of Influenza A Virus That Is Important for Its Shutoff Activity. Journal of Virology. 89: 8661-5. PMID 26041295 DOI: 10.1128/Jvi.01132-15  0.411
2015 Horimoto T, Gen F, Murakami S, Iwatsuki-Horimoto K, Kato K, Hisasue M, Sakaguchi M, Nidom CA, Kawaoka Y. Cats as a potential source of emerging influenza virus infections. Virologica Sinica. 30: 221-3. PMID 25953615 DOI: 10.1007/S12250-015-3580-9  0.669
2015 Chin AW, Perera RA, Guan Y, Halfmann P, Kawaoka Y, Peiris M, Poon LL. Pseudoparticle neutralization assay for detecting ebola- neutralizing antibodies in biosafety level 2 settings. Clinical Chemistry. 61: 885-6. PMID 25829407 DOI: 10.1373/Clinchem.2015.238204  0.533
2015 Marzi A, Halfmann P, Hill-Batorski L, Feldmann F, Shupert WL, Neumann G, Feldmann H, Kawaoka Y. Vaccines. An Ebola whole-virus vaccine is protective in nonhuman primates. Science (New York, N.Y.). 348: 439-42. PMID 25814063 DOI: 10.1126/Science.Aaa4919  0.444
2015 Neumann G, Kawaoka Y. Transmission of influenza A viruses. Virology. 479: 234-46. PMID 25812763 DOI: 10.1016/J.Virol.2015.03.009  0.693
2015 Fukuyama S, Katsura H, Zhao D, Ozawa M, Ando T, Shoemaker JE, Ishikawa I, Yamada S, Neumann G, Watanabe S, Kitano H, Kawaoka Y. Multi-spectral fluorescent reporter influenza viruses (Color-flu) as powerful tools for in vivo studies. Nature Communications. 6: 6600. PMID 25807527 DOI: 10.1038/Ncomms7600  0.66
2015 Takashita E, Kiso M, Fujisaki S, Yokoyama M, Nakamura K, Shirakura M, Sato H, Odagiri T, Kawaoka Y, Tashiro M. Characterization of a large cluster of influenza A(H1N1)pdm09 viruses cross-resistant to oseltamivir and peramivir during the 2013-2014 influenza season in Japan. Antimicrobial Agents and Chemotherapy. 59: 2607-17. PMID 25691635 DOI: 10.1128/Aac.04836-14  0.615
2015 Yamaji R, Yamada S, Le MQ, Ito M, Sakai-Tagawa Y, Kawaoka Y. Mammalian adaptive mutations of the PA protein of highly pathogenic avian H5N1 influenza virus. Journal of Virology. 89: 4117-25. PMID 25631084 DOI: 10.1128/Jvi.03532-14  0.665
2015 Yamayoshi S, Fukuyama S, Yamada S, Zhao D, Murakami S, Uraki R, Watanabe T, Tomita Y, Neumann G, Kawaoka Y. Amino acids substitutions in the PB2 protein of H7N9 influenza A viruses are important for virulence in mammalian hosts. Scientific Reports. 5: 8039. PMID 25623817 DOI: 10.1038/Srep08039  0.588
2015 Yamaji R, Yamada S, Le MQ, Li C, Chen H, Qurnianingsih E, Nidom CA, Ito M, Sakai-Tagawa Y, Kawaoka Y. Identification of PB2 mutations responsible for the efficient replication of H5N1 influenza viruses in human lung epithelial cells. Journal of Virology. 89: 3947-56. PMID 25609813 DOI: 10.1128/Jvi.03328-14  0.657
2015 Eisfeld AJ, Neumann G, Kawaoka Y. At the centre: influenza A virus ribonucleoproteins. Nature Reviews. Microbiology. 13: 28-41. PMID 25417656 DOI: 10.1038/Nrmicro3367  0.632
2015 Sugaya N, Sakai-Tagawa Y, Bamba M, Yasuhara R, Yamazaki M, Kawakami C, Yamaguchi Y, Ide Y, Ichikawa M, Mitamura K, Kawaoka Y. Comparison between virus shedding and fever duration after treating children with pandemic A H1N1/09 and children with A H3N2 with a neuraminidase inhibitor. Antiviral Therapy. 20: 49-55. PMID 24832015 DOI: 10.3851/Imp2798  0.653
2015 Shiraishi K, Mitamura K, Ozawa M, Kakugawa S, Kiso M, Sakai-Tagawa Y, Sugaya N, Kawaoka Y. Mutations in influenza A virus during amantadine-oseltamivir combination therapy Journal of Pediatric Infectious Diseases. 5: 243-248. DOI: 10.3233/Jpi-2010-0256  0.562
2014 Halfmann P, Neumann G, Feldmann H, Kawaoka Y. Ebola Conquers West Africa - More to Come? Ebiomedicine. 1: 2-3. PMID 26137502 DOI: 10.1016/J.Ebiom.2014.10.004  0.481
2014 Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, ... ... Kawaoka Y, et al. A comprehensive collection of systems biology data characterizing the host response to viral infection. Scientific Data. 1: 140033. PMID 25977790 DOI: 10.1038/Sdata.2014.33  0.353
2014 Watanabe T, Kawakami E, Shoemaker JE, Lopes TJ, Matsuoka Y, Tomita Y, Kozuka-Hata H, Gorai T, Kuwahara T, Takeda E, Nagata A, Takano R, Kiso M, Yamashita M, Sakai-Tagawa Y, ... ... Kawaoka Y, et al. Influenza virus-host interactome screen as a platform for antiviral drug development. Cell Host & Microbe. 16: 795-805. PMID 25464832 DOI: 10.1016/J.Chom.2014.11.002  0.531
2014 Li X, Shi J, Guo J, Deng G, Zhang Q, Wang J, He X, Wang K, Chen J, Li Y, Fan J, Kong H, Gu C, Guan Y, Suzuki Y, ... Kawaoka Y, et al. Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses. Plos Pathogens. 10: e1004508. PMID 25411973 DOI: 10.1371/Journal.Ppat.1004508  0.67
2014 Peng X, Alföldi J, Gori K, Eisfeld AJ, Tyler SR, Tisoncik-Go J, Brawand D, Law GL, Skunca N, Hatta M, Gasper DJ, Kelly SM, Chang J, Thomas MJ, Johnson J, ... ... Kawaoka Y, et al. The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease. Nature Biotechnology. 32: 1250-5. PMID 25402615 DOI: 10.1038/Nbt.3079  0.55
2014 Eisfeld AJ, Neumann G, Kawaoka Y. Influenza A virus isolation, culture and identification. Nature Protocols. 9: 2663-81. PMID 25321410 DOI: 10.1038/Nprot.2014.180  0.557
2014 Fan S, Hatta M, Kim JH, Halfmann P, Imai M, Macken CA, Le MQ, Nguyen T, Neumann G, Kawaoka Y. Novel residues in avian influenza virus PB2 protein affect virulence in mammalian hosts. Nature Communications. 5: 5021. PMID 25289523 DOI: 10.1038/Ncomms6021  0.577
2014 Watanabe T, Watanabe S, Maher EA, Neumann G, Kawaoka Y. Pandemic potential of avian influenza A (H7N9) viruses. Trends in Microbiology. 22: 623-31. PMID 25264312 DOI: 10.1016/J.Tim.2014.08.008  0.66
2014 Fan S, Hatta M, Kim JH, Le MQ, Neumann G, Kawaoka Y. Amino acid changes in the influenza A virus PA protein that attenuate avian H5N1 viruses in mammals. Journal of Virology. 88: 13737-46. PMID 25231317 DOI: 10.1128/Jvi.01081-14  0.666
2014 Florek NW, Weinfurter JT, Jegaskanda S, Brewoo JN, Powell TD, Young GR, Das SC, Hatta M, Broman KW, Hungnes O, Dudman SG, Kawaoka Y, Kent SJ, Stinchcomb DT, Osorio JE, et al. Modified vaccinia virus Ankara encoding influenza virus hemagglutinin induces heterosubtypic immunity in macaques. Journal of Virology. 88: 13418-28. PMID 25210172 DOI: 10.1128/Jvi.01219-14  0.594
2014 Katsura H, Piao Z, Iwatsuki-Horimoto K, Akeda Y, Watanabe S, Horimoto T, Oishi K, Kawaoka Y. A bivalent vaccine based on a replication-incompetent influenza virus protects against Streptococcus pneumoniae and influenza virus infection. Journal of Virology. 88: 13410-7. PMID 25210171 DOI: 10.1128/Jvi.01205-14  0.685
2014 Uraki R, Das SC, Hatta M, Kiso M, Iwatsuki-Horimoto K, Ozawa M, Coban C, Ishii KJ, Kawaoka Y. Hemozoin as a novel adjuvant for inactivated whole virion influenza vaccine. Vaccine. 32: 5295-300. PMID 25108216 DOI: 10.1016/J.Vaccine.2014.07.079  0.539
2014 Nagaoka M, Hatta Y, Kawaoka Y, Malherbe LP. Antigen signal strength during priming determines effector CD4 T cell function and antigen sensitivity during influenza virus challenge. Journal of Immunology (Baltimore, Md. : 1950). 193: 2812-20. PMID 25086170 DOI: 10.4049/Jimmunol.1401358  0.364
2014 Sakai-Tagawa Y, Ozawa M, Yamada S, Uchida Y, Saito T, Takahashi K, Sugaya N, Tashiro M, Kawaoka Y. Detection sensitivity of influenza rapid diagnostic tests. Microbiology and Immunology. 58: 600-6. PMID 25079880 DOI: 10.1111/1348-0421.12185  0.585
2014 Hatakeyama D, Shoji M, Yamayoshi S, Hirota T, Nagae M, Yanagisawa S, Nakano M, Ohmi N, Noda T, Kawaoka Y, Kuzuhara T. A novel functional site in the PB2 subunit of influenza A virus essential for acetyl-CoA interaction, RNA polymerase activity, and viral replication. The Journal of Biological Chemistry. 289: 24980-94. PMID 25063805 DOI: 10.1074/Jbc.M114.559708  0.455
2014 Herfst S, Imai M, Kawaoka Y, Fouchier RAM. Avian influenza virus transmission to mammals Current Topics in Microbiology and Immunology. 385: 137-155. PMID 25048542 DOI: 10.1007/82_2014_387  0.659
2014 Garulli B, Di Mario G, Stillitano MG, Compagnoni D, Titti F, Cafaro A, Ensoli B, Kawaoka Y, Castrucci MR. Induction of antibodies and t cell responses by a recombinant influenza virus carrying an HIV-1 Tat Δ51-59 protein in mice Biomed Research International. 2014. PMID 24949479 DOI: 10.1155/2014/904038  0.618
2014 Itoh Y, Yoshida R, Shichinohe S, Higuchi M, Ishigaki H, Nakayama M, Pham VL, Ishida H, Kitano M, Arikata M, Kitagawa N, Mitsuishi Y, Ogasawara K, Tsuchiya H, Hiono T, ... ... Kawaoka Y, et al. Protective efficacy of passive immunization with monoclonal antibodies in animal models of H5N1 highly pathogenic avian influenza virus infection. Plos Pathogens. 10: e1004192. PMID 24945244 DOI: 10.1371/Journal.Ppat.1004192  0.585
2014 Watanabe T, Zhong G, Russell CA, Nakajima N, Hatta M, Hanson A, McBride R, Burke DF, Takahashi K, Fukuyama S, Tomita Y, Maher EA, Watanabe S, Imai M, Neumann G, ... ... Kawaoka Y, et al. Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential. Cell Host & Microbe. 15: 692-705. PMID 24922572 DOI: 10.1016/J.Chom.2014.05.006  0.699
2014 Josset L, Tchitchek N, Gralinski LE, Ferris MT, Eisfeld AJ, Green RR, Thomas MJ, Tisoncik-Go J, Schroth GP, Kawaoka Y, Manuel de Villena FP, Baric RS, Heise MT, Peng X, Katze MG. Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts. Rna Biology. 11: 875-90. PMID 24922324 DOI: 10.4161/Rna.29442  0.449
2014 Kitano M, Itoh Y, Ishigaki H, Nakayama M, Ishida H, Pham VL, Arikata M, Shichinohe S, Tsuchiya H, Kitagawa N, Kobayashi M, Yoshida R, Sato A, Le QM, Kawaoka Y, et al. Efficacy of repeated intravenous administration of peramivir against highly pathogenic avian influenza A (H5N1) virus in cynomolgus macaques. Antimicrobial Agents and Chemotherapy. 58: 4795-803. PMID 24913156 DOI: 10.1128/Aac.02817-14  0.607
2014 Muramoto Y, Shoemaker JE, Le MQ, Itoh Y, Tamura D, Sakai-Tagawa Y, Imai H, Uraki R, Takano R, Kawakami E, Ito M, Okamoto K, Ishigaki H, Mimuro H, Sasakawa C, ... ... Kawaoka Y, et al. Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses. Journal of Virology. 88: 8981-97. PMID 24899188 DOI: 10.1128/Jvi.00907-14  0.558
2014 Menachery VD, Eisfeld AJ, Schäfer A, Josset L, Sims AC, Proll S, Fan S, Li C, Neumann G, Tilton SC, Chang J, Gralinski LE, Long C, Green R, Williams CM, ... ... Kawaoka Y, et al. Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses. Mbio. 5: e01174-14. PMID 24846384 DOI: 10.1128/Mbio.01174-14  0.626
2014 Kurebayashi Y, Takahashi T, Otsubo T, Ikeda K, Takahashi S, Takano M, Agarikuchi T, Sato T, Matsuda Y, Minami A, Kanazawa H, Uchida Y, Saito T, Kawaoka Y, Yamada T, et al. Imaging of influenza virus sialidase activity in living cells. Scientific Reports. 4: 4877. PMID 24786761 DOI: 10.1038/Srep04877  0.662
2014 Tani H, Iha K, Shimojima M, Fukushi S, Taniguchi S, Yoshikawa T, Kawaoka Y, Nakasone N, Ninomiya H, Saijo M, Morikawa S. Analysis of Lujo virus cell entry using pseudotype vesicular stomatitis virus. Journal of Virology. 88: 7317-30. PMID 24741091 DOI: 10.1128/Jvi.00512-14  0.544
2014 Garulli B, Di Mario G, Stillitano MG, Kawaoka Y, Castrucci MR. Exploring mucosal immunization with a recombinant influenza virus carrying an HIV-polyepitope in mice with pre-existing immunity to influenza. Vaccine. 32: 2501-6. PMID 24662706 DOI: 10.1016/J.Vaccine.2014.02.077  0.484
2014 Teijaro JR, Walsh KB, Long JP, Tordoff KP, Stark GV, Eisfeld AJ, Kawaoka Y, Rosen H, Oldstone MB. Protection of ferrets from pulmonary injury due to H1N1 2009 influenza virus infection: immunopathology tractable by sphingosine-1-phosphate 1 receptor agonist therapy. Virology. 452: 152-7. PMID 24606692 DOI: 10.1016/J.Virol.2014.01.003  0.544
2014 Sakai K, Ami Y, Tahara M, Kubota T, Anraku M, Abe M, Nakajima N, Sekizuka T, Shirato K, Suzaki Y, Ainai A, Nakatsu Y, Kanou K, Nakamura K, Suzuki T, ... ... Kawaoka Y, et al. The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses. Journal of Virology. 88: 5608-16. PMID 24600012 DOI: 10.1128/Jvi.03677-13  0.578
2014 Neumann G, Macken CA, Kawaoka Y. Identification of amino acid changes that may have been critical for the genesis of A(H7N9) influenza viruses. Journal of Virology. 88: 4877-96. PMID 24522919 DOI: 10.1128/Jvi.00107-14  0.658
2014 Liu Z, Kato A, Shindo K, Noda T, Sagara H, Kawaoka Y, Arii J, Kawaguchi Y. Herpes simplex virus 1 UL47 interacts with viral nuclear egress factors UL31, UL34, and Us3 and regulates viral nuclear egress. Journal of Virology. 88: 4657-67. PMID 24522907 DOI: 10.1128/Jvi.00137-14  0.488
2014 Wang G, Deng G, Shi J, Luo W, Zhang G, Zhang Q, Liu L, Jiang Y, Li C, Sriwilaijaroen N, Hiramatsu H, Suzuki Y, Kawaoka Y, Chen H. H6 influenza viruses pose a potential threat to human health. Journal of Virology. 88: 3953-64. PMID 24501418 DOI: 10.1128/Jvi.03292-13  0.576
2014 Castrucci MR, Facchini M, Di Mario G, Garulli B, Sciaraffia E, Meola M, Fabiani C, De Marco MA, Cordioli P, Siccardi A, Kawaoka Y, Donatelli I. Modified vaccinia virus Ankara expressing the hemagglutinin of pandemic (H1N1) 2009 virus induces cross-protective immunity against Eurasian 'avian-like' H1N1 swine viruses in mice. Influenza and Other Respiratory Viruses. 8: 367-75. PMID 24373385 DOI: 10.1111/Irv.12221  0.637
2014 Yamayoshi S, Yamada S, Fukuyama S, Murakami S, Zhao D, Uraki R, Watanabe T, Tomita Y, Macken C, Neumann G, Kawaoka Y. Virulence-affecting amino acid changes in the PA protein of H7N9 influenza A viruses. Journal of Virology. 88: 3127-34. PMID 24371069 DOI: 10.1128/Jvi.03155-13  0.616
2014 Horimoto T, Gen F, Murakami S, Iwatsuki-Horimoto K, Kato K, Akashi H, Hisasue M, Sakaguchi M, Kawaoka Y, Maeda K. Serological evidence of infection of dogs with human influenza viruses in Japan. The Veterinary Record. 174: 96. PMID 24336761 DOI: 10.1136/Vr.101929  0.661
2014 Fonseca W, Ozawa M, Hatta M, Orozco E, Martínez MB, Kawaoka Y. A recombinant influenza virus vaccine expressing the F protein of respiratory syncytial virus. Archives of Virology. 159: 1067-77. PMID 24292020 DOI: 10.1007/S00705-013-1932-Z  0.677
2014 de Vries RP, Zhu X, McBride R, Rigter A, Hanson A, Zhong G, Hatta M, Xu R, Yu W, Kawaoka Y, de Haan CA, Wilson IA, Paulson JC. Hemagglutinin receptor specificity and structural analyses of respiratory droplet-transmissible H5N1 viruses. Journal of Virology. 88: 768-73. PMID 24173215 DOI: 10.1128/Jvi.02690-13  0.449
2014 Saphire EO, Bornholdt ZA, Abelson DM, Halfmann P, Noda T, Wood M, Kawaoka Y. Structural Rearrangement of the Ebola Virus VP40 Protein Begets Multiple Functions in the Virus Life Cycle Biophysical Journal. 106: 637a. DOI: 10.1016/J.Bpj.2013.11.3524  0.498
2014 Kawaoka Y, Neumann G. Reverse genetics approaches for rational design of inactivated and live attenuated influenza vaccines Novel Technologies For Vaccine Development. 3-32. DOI: 10.1007/978-3-7091-1818-4_1  0.415
2013 Ozawa M, Kawaoka Y. Cross talk between animal and human influenza viruses. Annual Review of Animal Biosciences. 1: 21-42. PMID 25387011 DOI: 10.1146/Annurev-Animal-031412-103733  0.655
2013 Watanabe T, Watanabe S, Kawaoka Y. [Cutting-edge of medicine; pandemic potential of H5N1 influenza virus]. Nihon Naika Gakkai Zasshi. the Journal of the Japanese Society of Internal Medicine. 102: 2705-13. PMID 24400555 DOI: 10.2169/Naika.102.2705  0.654
2013 Nakayama M, Shichinohe S, Itoh Y, Ishigaki H, Kitano M, Arikata M, Pham VL, Ishida H, Kitagawa N, Okamatsu M, Sakoda Y, Ichikawa T, Tsuchiya H, Nakamura S, Le QM, ... ... Kawaoka Y, et al. Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine. Plos One. 8: e82740. PMID 24376571 DOI: 10.1371/Journal.Pone.0082740  0.638
2013 Wilker PR, Dinis JM, Starrett G, Imai M, Hatta M, Nelson CW, O'Connor DH, Hughes AL, Neumann G, Kawaoka Y, Friedrich TC. Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses. Nature Communications. 4: 2636. PMID 24149915 DOI: 10.1038/Ncomms3636  0.66
2013 Kobayashi H, Iwatsuki-Horimoto K, Kiso M, Uraki R, Ichiko Y, Takimoto T, Kawaoka Y. A replication-incompetent influenza virus bearing the HN glycoprotein of human parainfluenza virus as a bivalent vaccine. Vaccine. 31: 6239-46. PMID 24144478 DOI: 10.1016/J.Vaccine.2013.10.029  0.668
2013 Hill-Batorski L, Halfmann P, Neumann G, Kawaoka Y. The cytoprotective enzyme heme oxygenase-1 suppresses Ebola virus replication. Journal of Virology. 87: 13795-802. PMID 24109237 DOI: 10.1128/Jvi.02422-13  0.547
2013 Matsuoka Y, Matsumae H, Katoh M, Eisfeld AJ, Neumann G, Hase T, Ghosh S, Shoemaker JE, Lopes TJ, Watanabe T, Watanabe S, Fukuyama S, Kitano H, Kawaoka Y. A comprehensive map of the influenza A virus replication cycle. Bmc Systems Biology. 7: 97. PMID 24088197 DOI: 10.1186/1752-0509-7-97  0.634
2013 Sugita Y, Sagara H, Noda T, Kawaoka Y. Configuration of viral ribonucleoprotein complexes within the influenza A virion. Journal of Virology. 87: 12879-84. PMID 24067952 DOI: 10.1128/Jvi.02096-13  0.54
2013 Imai M, Herfst S, Sorrell EM, Schrauwen EJA, Linster M, De Graaf M, Fouchier RAM, Kawaoka Y. Transmission of influenza A/H5N1 viruses in mammals Virus Research. 178: 15-20. PMID 23954580 DOI: 10.1016/J.Virusres.2013.07.017  0.655
2013 Bornholdt ZA, Noda T, Abelson DM, Halfmann P, Wood MR, Kawaoka Y, Saphire EO. Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle. Cell. 154: 763-74. PMID 23953110 DOI: 10.1016/J.Cell.2013.07.015  0.48
2013 Mitchell HD, Eisfeld AJ, Sims AC, McDermott JE, Matzke MM, Webb-Robertson BJ, Tilton SC, Tchitchek N, Josset L, Li C, Ellis AL, Chang JH, Heegel RA, Luna ML, Schepmoes AA, ... ... Kawaoka Y, et al. A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses. Plos One. 8: e69374. PMID 23935999 DOI: 10.1371/Journal.Pone.0069374  0.565
2013 Fouchier RA, Kawaoka Y, Cardona C, Compans RW, García-Sastre A, Govorkova EA, Guan Y, Herfst S, Orenstein WA, Peiris JS, Perez DR, Richt JA, Russell C, Schultz-Cherry SL, Smith DJ, et al. Gain-of-function experiments on H7N9. Science (New York, N.Y.). 341: 612-3. PMID 23929965 DOI: 10.1126/science.341.6146.612  0.306
2013 Goto H, Muramoto Y, Noda T, Kawaoka Y. The genome-packaging signal of the influenza A virus genome comprises a genome incorporation signal and a genome-bundling signal. Journal of Virology. 87: 11316-22. PMID 23926345 DOI: 10.1128/Jvi.01301-13  0.405
2013 Fouchier RA, Kawaoka Y, Cardona C, Compans RW, García-Sastre A, Govorkova EA, Guan Y, Herfst S, Orenstein WA, Peiris JS, Perez DR, Richt JA, Russell C, Schultz-Cherry SL, Smith DJ, et al. Gain-of-Function Experiments on H7N9. Science (New York, N.Y.). PMID 23926190 DOI: 10.1126/Science.1243325  0.656
2013 Fouchier RA, Kawaoka Y, Cardona C, Compans RW, Fouchier RA, García-Sastre A, Govorkova EA, Guan Y, Herfst S, Kawaoka Y, Orenstein WA, Peiris JS, Perez DR, Richt JA, Russell C, et al. Avian flu: Gain-of-function experiments on H7N9. Nature. 500: 150-1. PMID 23925229 DOI: 10.1038/500150A  0.476
2013 Tchitchek N, Eisfeld AJ, Tisoncik-Go J, Josset L, Gralinski LE, Bécavin C, Tilton SC, Webb-Robertson BJ, Ferris MT, Totura AL, Li C, Neumann G, Metz TO, Smith RD, Waters KM, ... ... Kawaoka Y, et al. Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice. Bmc Systems Biology. 7: 69. PMID 23895213 DOI: 10.1186/1752-0509-7-69  0.543
2013 Watanabe T, Kiso M, Fukuyama S, Nakajima N, Imai M, Yamada S, Murakami S, Yamayoshi S, Iwatsuki-Horimoto K, Sakoda Y, Takashita E, McBride R, Noda T, Hatta M, Imai H, ... ... Kawaoka Y, et al. Characterization of H7N9 influenza A viruses isolated from humans. Nature. 501: 551-5. PMID 23842494 DOI: 10.1038/Nature12392  0.676
2013 Deng G, Tan D, Shi J, Cui P, Jiang Y, Liu L, Tian G, Kawaoka Y, Li C, Chen H. Complex reassortment of multiple subtypes of avian influenza viruses in domestic ducks at the Dongting Lake Region of China. Journal of Virology. 87: 9452-62. PMID 23804642 DOI: 10.1128/Jvi.00776-13  0.529
2013 Takahashi T, Song J, Suzuki T, Kawaoka Y. Mutations in NA that induced low pH-stability and enhanced the replication of pandemic (H1N1) 2009 influenza A virus at an early stage of the pandemic. Plos One. 8: e64439. PMID 23696893 DOI: 10.1371/Journal.Pone.0064439  0.612
2013 Takahashi K, Halfmann P, Oyama M, Kozuka-Hata H, Noda T, Kawaoka Y. DNA topoisomerase 1 facilitates the transcription and replication of the Ebola virus genome. Journal of Virology. 87: 8862-9. PMID 23658456 DOI: 10.1128/Jvi.03544-12  0.44
2013 Uraki R, Kiso M, Iwatsuki-Horimoto K, Fukuyama S, Takashita E, Ozawa M, Kawaoka Y. A novel bivalent vaccine based on a PB2-knockout influenza virus protects mice from pandemic H1N1 and highly pathogenic H5N1 virus challenges. Journal of Virology. 87: 7874-81. PMID 23658445 DOI: 10.1128/Jvi.00076-13  0.628
2013 Xiong X, Coombs PJ, Martin SR, Liu J, Xiao H, McCauley JW, Locher K, Walker PA, Collins PJ, Kawaoka Y, Skehel JJ, Gamblin SJ. Receptor binding by a ferret-transmissible H5 avian influenza virus. Nature. 497: 392-6. PMID 23615615 DOI: 10.1038/Nature12144  0.534
2013 Kageyama T, Fujisaki S, Takashita E, Xu H, Yamada S, Uchida Y, Neumann G, Saito T, Kawaoka Y, Tashiro M. Genetic analysis of novel avian A(H7N9) influenza viruses isolated from patients in China, February to April 2013. Euro Surveillance : Bulletin Europã©En Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. 18: 20453. PMID 23594575 DOI: 10.2807/Ese.18.15.20453-En  0.661
2013 Kiso M, Takano R, Sakabe S, Katsura H, Shinya K, Uraki R, Watanabe S, Saito H, Toba M, Kohda N, Kawaoka Y. Protective efficacy of orally administered, heat-killed Lactobacillus pentosus b240 against influenza A virus. Scientific Reports. 3: 1563. PMID 23535544 DOI: 10.1038/Srep01563  0.544
2013 Morita M, Kuba K, Ichikawa A, Nakayama M, Katahira J, Iwamoto R, Watanebe T, Sakabe S, Daidoji T, Nakamura S, Kadowaki A, Ohto T, Nakanishi H, Taguchi R, Nakaya T, ... ... Kawaoka Y, et al. The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza. Cell. 153: 112-25. PMID 23477864 DOI: 10.1016/J.Cell.2013.02.027  0.587
2013 Watanabe T, Tisoncik-Go J, Tchitchek N, Watanabe S, Benecke AG, Katze MG, Kawaoka Y. 1918 Influenza virus hemagglutinin (HA) and the viral RNA polymerase complex enhance viral pathogenicity, but only HA induces aberrant host responses in mice. Journal of Virology. 87: 5239-54. PMID 23449804 DOI: 10.1128/Jvi.02753-12  0.667
2013 Fan S, Macken CA, Li C, Ozawa M, Goto H, Iswahyudi NF, Nidom CA, Chen H, Neumann G, Kawaoka Y. Synergistic effect of the PDZ and p85β-binding domains of the NS1 protein on virulence of an avian H5N1 influenza A virus. Journal of Virology. 87: 4861-71. PMID 23408626 DOI: 10.1128/Jvi.02608-12  0.597
2013 Nanbo A, Watanabe S, Halfmann P, Kawaoka Y. The spatio-temporal distribution dynamics of Ebola virus proteins and RNA in infected cells. Scientific Reports. 3: 1206. PMID 23383374 DOI: 10.1038/Srep01206  0.443
2013 Fouchier RA, García-Sastre A, Kawaoka Y. H5N1 virus: Transmission studies resume for avian flu. Nature. 493: 609. PMID 23354044 DOI: 10.1038/Nature11858  0.668
2013 Ozawa M, Shimojima M, Goto H, Watanabe S, Hatta Y, Kiso M, Furuta Y, Horimoto T, Peters NR, Hoffmann FM, Kawaoka Y. A cell-based screening system for influenza A viral RNA transcription/replication inhibitors. Scientific Reports. 3: 1106. PMID 23346363 DOI: 10.1038/Srep01106  0.545
2013 Fouchier RA, García-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, et al. Transmission studies resume for avian flu. Science (New York, N.Y.). 339: 520-1. PMID 23345603 DOI: 10.1126/Science.1235140  0.519
2013 Van Kerkhove MD, Hirve S, Koukounari A, Mounts AW, Allwinn R, Bandaranayake DD, Bella AA, Bone A, Carrat F, Chadha MS, Chen M, Chi CY, Cox CMCM, Cretikos M, Crowcroft N, ... ... Kawaoka Y, et al. Estimating age-specific cumulative incidence for the 2009 influenza pandemic: A meta-analysis of A(H1N1)pdm09 serological studies from 19 countries Influenza and Other Respiratory Viruses. 7: 872-886. PMID 23331969 DOI: 10.1111/irv.12074  0.49
2013 Marzi A, Engelmann F, Feldmann F, Haberthur K, Shupert WL, Brining D, Scott DP, Geisbert TW, Kawaoka Y, Katze MG, Feldmann H, Messaoudi I. Antibodies are necessary for rVSV/ZEBOV-GP-mediated protection against lethal Ebola virus challenge in nonhuman primates. Proceedings of the National Academy of Sciences of the United States of America. 110: 1893-8. PMID 23319647 DOI: 10.1073/Pnas.1209591110  0.406
2013 Schaefer MH, Lopes TJ, Mah N, Shoemaker JE, Matsuoka Y, Fontaine JF, Louis-Jeune C, Eisfeld AJ, Neumann G, Perez-Iratxeta C, Kawaoka Y, Kitano H, Andrade-Navarro MA. Adding protein context to the human protein-protein interaction network to reveal meaningful interactions. Plos Computational Biology. 9: e1002860. PMID 23300433 DOI: 10.1371/Journal.Pcbi.1002860  0.352
2013 Fehling SK, Noda T, Maisner A, Lamp B, Conzelmann KK, Kawaoka Y, Klenk HD, Garten W, Strecker T. The microtubule motor protein KIF13A is involved in intracellular trafficking of the Lassa virus matrix protein Z. Cellular Microbiology. 15: 315-34. PMID 23279019 DOI: 10.1111/Cmi.12095  0.381
2013 Gen F, Yamada S, Kato K, Akashi H, Kawaoka Y, Horimoto T. Attenuation of an influenza A virus due to alteration of its hemagglutinin-neuraminidase functional balance in mice. Archives of Virology. 158: 1003-11. PMID 23247916 DOI: 10.1007/S00705-012-1577-3  0.638
2013 Muramoto Y, Noda T, Kawakami E, Akkina R, Kawaoka Y. Identification of novel influenza A virus proteins translated from PA mRNA. Journal of Virology. 87: 2455-62. PMID 23236060 DOI: 10.1128/Jvi.02656-12  0.63
2013 Uraki R, Kiso M, Shinya K, Goto H, Takano R, Iwatsuki-Horimoto K, Takahashi K, Daniels RS, Hungnes O, Watanabe T, Kawaoka Y. Virulence determinants of pandemic A(H1N1)2009 influenza virus in a mouse model. Journal of Virology. 87: 2226-33. PMID 23221570 DOI: 10.1128/Jvi.01565-12  0.685
2013 Ichikawa A, Kuba K, Morita M, Chida S, Tezuka H, Hara H, Sasaki T, Ohteki T, Ranieri VM, dos Santos CC, Kawaoka Y, Akira S, Luster AD, Lu B, Penninger JM, et al. CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin. American Journal of Respiratory and Critical Care Medicine. 187: 65-77. PMID 23144331 DOI: 10.1164/Rccm.201203-0508Oc  0.505
2013 Takano R, Kiso M, Igarashi M, Le QM, Sekijima M, Ito K, Takada A, Kawaoka Y. Molecular mechanisms underlying oseltamivir resistance mediated by an I117V substitution in the neuraminidase of subtype H5N1 avian influenza a viruses Journal of Infectious Diseases. 207: 89-97. PMID 23053629 DOI: 10.1093/Infdis/Jis633  0.619
2013 Ebihara H, Zivcec M, Gardner D, Falzarano D, LaCasse R, Rosenke R, Long D, Haddock E, Fischer E, Kawaoka Y, Feldmann H. A Syrian golden hamster model recapitulating ebola hemorrhagic fever. The Journal of Infectious Diseases. 207: 306-18. PMID 23045629 DOI: 10.1093/Infdis/Jis626  0.405
2013 Sakabe S, Takano R, Nagamura-Inoue T, Yamashita N, Nidom CA, Quynh Le MT, Iwatsuki-Horimoto K, Kawaoka Y. Differences in cytokine production in human macrophages and in virulence in mice are attributable to the acidic polymerase protein of highly pathogenic influenza A virus subtype H5N1 Journal of Infectious Diseases. 207: 262-271. PMID 23042757 DOI: 10.1093/Infdis/Jis523  0.594
2012 Takahashi T, Nidom CA, Quynh Le MT, Suzuki T, Kawaoka Y. Amino acid determinants conferring stable sialidase activity at low pH for H5N1 influenza A virus neuraminidase. Febs Open Bio. 2: 261-6. PMID 23650608 DOI: 10.1016/j.fob.2012.08.007  0.497
2012 Neumann G, Macken CA, Karasin AI, Fouchier RA, Kawaoka Y. Egyptian H5N1 influenza viruses-cause for concern? Plos Pathogens. 8: e1002932. PMID 23166487 DOI: 10.1371/Journal.Ppat.1002932  0.678
2012 Fouchier RAM, García-Sastre A, Kawaoka Y. The pause on avian H5N1 influenza virus transmission research should be ended Mbio. 3. PMID 23047750 DOI: 10.1128/Mbio.00358-12  0.587
2012 Kajihara M, Marzi A, Nakayama E, Noda T, Kuroda M, Manzoor R, Matsuno K, Feldmann H, Yoshida R, Kawaoka Y, Takada A. Inhibition of marburg virus budding by nonneutralizing antibodiesto the envelope glycoprotein Journal of Virology. 86: 13467-13474. PMID 23035224 DOI: 10.1128/Jvi.01896-12  0.481
2012 Bale S, Julien JP, Bornholdt ZA, Kimberlin CR, Halfmann P, Zandonatti MA, Kunert J, Kroon GJ, Kawaoka Y, MacRae IJ, Wilson IA, Saphire EO. Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism. Plos Pathogens. 8: e1002916. PMID 23028316 DOI: 10.1371/Journal.Ppat.1002916  0.428
2012 Takashita E, Muraki Y, Sugawara K, Asao H, Nishimura H, Suzuki K, Tsuji T, Hongo S, Ohara Y, Ohara Y, Kawaoka Y, Ozawa M, Matsuzaki Y. Intrinsic temperature sensitivity of influenza C virus hemagglutinin-esterase-fusion protein. Journal of Virology. 86: 13108-11. PMID 23015703 DOI: 10.1128/Jvi.01925-12  0.534
2012 Das SC, Hatta M, Wilker PR, Myc A, Hamouda T, Neumann G, Baker JR, Kawaoka Y. Nanoemulsion W805EC improves immune responses upon intranasal delivery of an inactivated pandemic H1N1 influenza vaccine. Vaccine. 30: 6871-7. PMID 22989689 DOI: 10.1016/J.Vaccine.2012.09.007  0.426
2012 Shoemaker JE, Fukuyama S, Eisfeld AJ, Muramoto Y, Watanabe S, Watanabe T, Matsuoka Y, Kitano H, Kawaoka Y. Integrated network analysis reveals a novel role for the cell cycle in 2009 pandemic influenza virus-induced inflammation in macaque lungs. Bmc Systems Biology. 6: 117. PMID 22937776 DOI: 10.1186/1752-0509-6-117  0.686
2012 Kingstad-Bakke B, Brewoo JN, Mai LQ, Kawaoka Y, Osorio JE. Effects of route and coadministration of recombinant raccoon poxviruses on immune responses and protection against highly pathogenic avian influenza in mice Vaccine. 30: 6402-6408. PMID 22921740 DOI: 10.1016/J.Vaccine.2012.08.018  0.603
2012 Ilyushina NA, Ikizler MR, Kawaoka Y, Rudenko LG, Treanor JJ, Subbarao K, Wright PF. Comparative study of influenza virus replication in MDCK cells and in primary cells derived from adenoids and airway epithelium. Journal of Virology. 86: 11725-34. PMID 22915797 DOI: 10.1128/Jvi.01477-12  0.612
2012 Imai M, Watanabe S, Kawaoka Y. The cytoplasmic tail domain of influenza B virus hemagglutinin is important for its incorporation into virions but is not essential for virus replication in cell culture in the presence of compensatory mutations Journal of Virology. 86: 11633-11644. PMID 22896616 DOI: 10.1128/Jvi.01479-12  0.631
2012 Katsura H, Iwatsuki-Horimoto K, Fukuyama S, Watanabe S, Sakabe S, Hatta Y, Murakami S, Shimojima M, Horimoto T, Kawaoka Y. A replication-incompetent virus possessing an uncleavable hemagglutinin as an influenza vaccine. Vaccine. 30: 6027-33. PMID 22867723 DOI: 10.1016/J.Vaccine.2012.07.059  0.667
2012 Inagaki A, Goto H, Kakugawa S, Ozawa M, Kawaoka Y. Competitive incorporation of homologous gene segments of influenza A virus into virions Journal of Virology. 86: 10200-10202. PMID 22740412 DOI: 10.1128/Jvi.01204-12  0.557
2012 Zhang Y, Zhang Q, Gao Y, He X, Kong H, Jiang Y, Guan Y, Xia X, Shu Y, Kawaoka Y, Bu Z, Chen H. Key molecular factors in hemagglutinin and PB2 contribute to efficient transmission of the 2009 H1N1 pandemic influenza virus. Journal of Virology. 86: 9666-74. PMID 22740390 DOI: 10.1128/Jvi.00958-12  0.675
2012 Russell CA, Fonville JM, Brown AE, Burke DF, Smith DL, James SL, Herfst S, van Boheemen S, Linster M, Schrauwen EJ, Katzelnick L, Mosterín A, Kuiken T, Maher E, Neumann G, ... ... Kawaoka Y, et al. The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host. Science (New York, N.Y.). 336: 1541-7. PMID 22723414 DOI: 10.1126/Science.1222526  0.67
2012 Imai M, Watanabe T, Hatta M, Das SC, Ozawa M, Shinya K, Zhong G, Hanson A, Katsura H, Watanabe S, Li C, Kawakami E, Yamada S, Kiso M, Suzuki Y, ... ... Kawaoka Y, et al. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets Nature. 486: 420-428. PMID 22722205 DOI: 10.1038/Nature10831  0.665
2012 Watanabe T, Imai M, Watanabe S, Shinya K, Hatta M, Li C, Neumann G, Ozawa M, Hanson A, Zhong G, Fukuyama S, Kawakami E, Simmons HA, Schenkman D, Brunner K, ... ... Kawaoka Y, et al. Characterization in vitro and in vivo of pandemic (H1N1) 2009 influenza viruses isolated from patients. Journal of Virology. 86: 9361-8. PMID 22718834 DOI: 10.1128/Jvi.01214-12  0.621
2012 Shimojima M, Kawaoka Y. Cell surface molecules involved in infection mediated by lymphocytic choriomeningitis virus glycoprotein Journal of Veterinary Medical Science. 74: 1363-1366. PMID 22673088 DOI: 10.1292/Jvms.12-0176  0.44
2012 Chu C, Fan S, Li C, Macken C, Kim JH, Hatta M, Neumann G, Kawaoka Y. Functional analysis of conserved motifs in influenza virus PB1 protein. Plos One. 7: e36113. PMID 22615752 DOI: 10.1371/Journal.Pone.0036113  0.608
2012 Noda T, Kawaoka Y. Packaging of influenza virus genome: Robustness of selection Proceedings of the National Academy of Sciences of the United States of America. 109: 8797-8798. PMID 22615368 DOI: 10.1073/Pnas.1206736109  0.584
2012 Neumann G, Ozawa M, Kawaoka Y. Reverse genetics of influenza viruses Methods in Molecular Biology. 865: 193-206. PMID 22528161 DOI: 10.1007/978-1-61779-621-0_12  0.634
2012 Kawaoka Y, Neumann G. Influenza viruses: an introduction. Methods in Molecular Biology (Clifton, N.J.). 865: 1-9. PMID 22528150 DOI: 10.1007/978-1-61779-621-0_1  0.584
2012 Kawaoka Y, Neumann G. Influenza viruses: an introduction. Methods in Molecular Biology (Clifton, N.J.). 865: 1-9. PMID 22528150 DOI: 10.1007/978-1-61779-621-0_1  0.584
2012 Kikuchi T, Iwatsuki-Horimoto K, Adachi E, Koga M, Nakamura H, Hosoya N, Kawana-Tachikawa A, Koibuchi T, Miura T, Fujii T, Kawaoka Y, Iwamoto A. Improved neutralizing antibody response in the second season after a single dose of pandemic (H1N1) 2009 influenza vaccine in HIV-1-positive adults. Vaccine. 30: 3819-23. PMID 22504038 DOI: 10.1016/J.Vaccine.2012.03.083  0.395
2012 Shinya K, Gao Y, Cilloniz C, Suzuki Y, Fujie M, Deng G, Zhu Q, Fan S, Makino A, Muramoto Y, Fukuyama S, Tamura D, Noda T, Eisfeld AJ, Katze MG, ... ... Kawaoka Y, et al. Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque. Journal of Virology. 86: 6055-66. PMID 22491448 DOI: 10.1128/Jvi.00365-12  0.642
2012 Imai M, Kawaoka Y. The role of receptor binding specificity in interspecies transmission of influenza viruses Current Opinion in Virology. 2: 160-167. PMID 22445963 DOI: 10.1016/J.Coviro.2012.03.003  0.633
2012 Gorai T, Goto H, Noda T, Watanabe T, Kozuka-Hata H, Oyama M, Takano R, Neumann G, Watanabe S, Kawaoka Y. F1Fo-ATPase, F-type proton-translocating ATPase, at the plasma membrane is critical for efficient influenza virus budding Proceedings of the National Academy of Sciences of the United States of America. 109: 4615-4620. PMID 22393008 DOI: 10.1073/Pnas.1114728109  0.604
2012 Bharat TA, Noda T, Riches JD, Kraehling V, Kolesnikova L, Becker S, Kawaoka Y, Briggs JA. Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography. Proceedings of the National Academy of Sciences of the United States of America. 109: 4275-80. PMID 22371572 DOI: 10.1073/Pnas.1120453109  0.548
2012 Nidom CA, Yamada S, Nidom RV, Rahmawati K, Alamudi MY, Kholik, Indrasari S, Hayati RS, Iwatsuki Horimoto K, Kawaoka Y. Genetic characterization of H5N1 influenza viruses isolated from chickens in Indonesia in 2010 Virus Genes. 44: 459-465. PMID 22323117 DOI: 10.1007/S11262-012-0722-0  0.655
2012 Victor ST, Watanabe S, Katsura H, Ozawa M, Kawaoka Y. A replication-incompetent PB2-knockout influenza a virus vaccine vector Journal of Virology. 86: 4123-4128. PMID 22301144 DOI: 10.1128/Jvi.06232-11  0.654
2012 Kawai Y, Kimura Y, Lezhava A, Kanamori H, Usui K, Hanami T, Soma T, Morlighem JÉ, Saga S, Ishizu Y, Aoki S, Endo R, Oguchi-Katayama A, Kogo Y, Mitani Y, ... ... Kawaoka Y, et al. One-step detection of the 2009 pandemic influenza A(H1N1) virus by the RT-SmartAmp assay and its clinical validation. Plos One. 7: e30236. PMID 22295077 DOI: 10.1371/Journal.Pone.0030236  0.654
2012 Fouchier RA, García-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, et al. Pause on avian flu transmission research. Science (New York, N.Y.). 335: 400-1. PMID 22282787 DOI: 10.1126/science.335.6067.400  0.635
2012 Shi J, Wen Z, Guo J, Zhang Y, Deng G, Shu Y, Wang D, Jiang Y, Kawaoka Y, Bu Z, Chen H. Protective efficacy of an H1N1 cold-adapted live vaccine against the 2009 pandemic H1N1, seasonal H1N1, and H5N1 influenza viruses in mice Antiviral Research. 93: 346-353. PMID 22281419 DOI: 10.1016/J.Antiviral.2012.01.001  0.677
2012 Kawaoka Y. H5N1: Flu transmission work is urgent Nature. 482: 155. PMID 22278057 DOI: 10.1038/Nature10884  0.533
2012 Noda T, Sugita Y, Aoyama K, Hirase A, Kawakami E, Miyazawa A, Sagara H, Kawaoka Y. Three-dimensional analysis of ribonucleoprotein complexes in influenza A virus. Nature Communications. 3: 639. PMID 22273677 DOI: 10.1038/Ncomms1647  0.503
2012 Fouchier RAM, García-Sastre A, Kawaoka Y. Pause on avian flu transmission studies Nature. 481: 443. PMID 22266939 DOI: 10.1038/481443A  0.41
2012 Olal D, Kuehne AI, Bale S, Halfmann P, Hashiguchi T, Fusco ML, Lee JE, King LB, Kawaoka Y, Dye JM, Saphire EO. Structure of an antibody in complex with its mucin domain linear epitope that is protective against Ebola virus. Journal of Virology. 86: 2809-16. PMID 22171276 DOI: 10.1128/Jvi.05549-11  0.458
2012 Shimojima M, Ströher U, Ebihara H, Feldmann H, Kawaoka Y. Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry Journal of Virology. 86: 2067-2078. PMID 22156524 DOI: 10.1128/Jvi.06451-11  0.474
2012 Das SC, Watanabe S, Hatta M, Noda T, Neumann G, Ozawa M, Kawaoka Y. The Highly Conserved Arginine Residues at Positions 76 through 78 of Influenza A Virus Matrix Protein M1 Play an Important Role in Viral Replication by Affecting the Intracellular Localization of M1 Journal of Virology. 86: 1522-1530. PMID 22090133 DOI: 10.1128/Jvi.06230-11  0.583
2012 Murakami S, Horimoto T, Ito M, Takano R, Katsura H, Shimojima M, Kawaoka Y. Enhanced growth of influenza vaccine seed viruses in vero cells mediated by broadening the optimal pH range for virus membrane fusion. Journal of Virology. 86: 1405-10. PMID 22090129 DOI: 10.1128/Jvi.06009-11  0.511
2012 Yamada S, Shinya K, Takada A, Ito T, Suzuki T, Suzuki Y, Le QM, Ebina M, Kasai N, Kida H, Horimoto T, Rivailler P, Chen LM, Donis RO, Kawaoka Y. Adaptation of a duck influenza A virus in quail. Journal of Virology. 86: 1411-20. PMID 22090115 DOI: 10.1128/Jvi.06100-11  0.672
2012 Shinya K, Ito M, Makino A, Tanaka M, Miyake K, Eisfeld AJ, Kawaoka Y. The TLR4-TRIF pathway protects against H5N1 influenza virus infection Journal of Virology. 86: 19-24. PMID 22031950 DOI: 10.1128/Jvi.06168-11  0.532
2012 Ginting TE, Shinya K, Kyan Y, Makino A, Matsumoto N, Kaneda S, Kawaoka Y. Amino acid changes in hemagglutinin contribute to the replication of oseltamivir-resistant H1N1 influenza viruses Journal of Virology. 86: 121-127. PMID 22013054 DOI: 10.1128/Jvi.06085-11  0.531
2012 Olal D, Kuehne A, Bale S, Halfmann P, Hashiguchi T, Fusco ML, Lee JE, King LB, Kawaoka Y, Dye JM, Saphire EO. Structure of an Ebola Virus-Protective Antibody in Complex with its Mucin-Domain Linear Epitope. Journal of Virology. 86: 2809. DOI: 10.2210/Pdb2Y6S/Pdb  0.43
2012 Takahashi T, Nidom CA, Quynh Le Mt, Suzuki T, Kawaoka Y. Amino acid determinants conferring stable sialidase activity at low pH for H5N1 influenza A virus neuraminidase Febs Open Bio. 2: 261-266. DOI: 10.1016/J.Fob.2012.08.007  0.58
2012 Menachery V, Sims A, Eisfeld A, Gralinski L, Chang J, Waters K, Metz T, Kawaoka Y, Katze M, Baric R. P115 Pathogenic Influenza A viruses and SARS-Coronaviruses modulate global interferon stimulated gene induction through diverse mechanisms Cytokine. 59: 556. DOI: 10.1016/J.Cyto.2012.06.206  0.607
2011 Tanaka M, Tsumura K, Ito H, Ito T, Ono E, Makino A, Kawaoka Y, Shinya K. Characteristics of influenza virus genome mutations Kobe Journal of Medical Sciences. 57: E116-E127. PMID 22971946  0.574
2011 Weinfurter JT, Brunner K, Capuano SV, Li C, Broman KW, Kawaoka Y, Friedrich TC. Cross-reactive T cells are involved in rapid clearance of 2009 pandemic H1N1 influenza virus in nonhuman primates. Plos Pathogens. 7: e1002381. PMID 22102819 DOI: 10.1371/Journal.Ppat.1002381  0.554
2011 Dias JM, Kuehne AI, Abelson DM, Bale S, Wong AC, Halfmann P, Muhammad MA, Fusco ML, Zak SE, Kang E, Kawaoka Y, Chandran K, Dye JM, Saphire EO. A shared structural solution for neutralizing ebolaviruses. Nature Structural & Molecular Biology. 18: 1424-7. PMID 22101933 DOI: 10.1038/Nsmb.2150  0.406
2011 Peng X, Gralinski L, Ferris MT, Frieman MB, Thomas MJ, Proll S, Korth MJ, Tisoncik JR, Heise M, Luo S, Schroth GP, Tumpey TM, Li C, Kawaoka Y, Baric RS, et al. Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection. Mbio. 2. PMID 22086488 DOI: 10.1128/Mbio.00198-11  0.46
2011 McDermott JE, Shankaran H, Eisfeld AJ, Belisle SE, Neuman G, Li C, McWeeney S, Sabourin C, Kawaoka Y, Katze MG, Waters KM. Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems. Bmc Systems Biology. 5: 190. PMID 22074594 DOI: 10.1186/1752-0509-5-190  0.529
2011 Garulli B, Di Mario G, Sciaraffia E, Kawaoka Y, Castrucci MR. Immunogenicity of a recombinant influenza virus bearing both the CD4+ and CD8+ T cell epitopes of ovalbumin Journal of Biomedicine and Biotechnology. 2011. PMID 22007143 DOI: 10.1155/2011/497364  0.433
2011 Iwasa A, Halfmann P, Noda T, Oyama M, Kozuka-Hata H, Watanabe S, Shimojima M, Watanabe T, Kawaoka Y. Contribution of sec61α to the life cycle of Ebola virus Journal of Infectious Diseases. 204: S919-S926. PMID 21987770 DOI: 10.1093/Infdis/Jir324  0.483
2011 Iwasa A, Shimojima M, Kawaoka Y. SGP serves as a structural protein in ebola virus infection Journal of Infectious Diseases. 204: S897-S903. PMID 21987767 DOI: 10.1093/Infdis/Jir313  0.384
2011 Noda T, Kolesnikova L, Becker S, Kawaoka Y. The importance of the NP: VP35 ratio in Ebola virus nucleocapsid formation Journal of Infectious Diseases. 204: S878-S883. PMID 21987764 DOI: 10.1093/Infdis/Jir310  0.42
2011 Makino A, Yamayoshi S, Shinya K, Noda T, Kawaoka Y. Identification of amino acids in marburg virus VP40 that are important for virus-like particle budding Journal of Infectious Diseases. 204: S871-S877. PMID 21987763 DOI: 10.1093/Infdis/Jir309  0.549
2011 Hatakeyama S, Iwatsuki-Horimoto K, Okamoto K, Nukui Y, Yata N, Fujita A, Inaba S, Yotsuyanagi H, Kawaoka Y. Unadjuvanted pandemic H1N1 influenza vaccine in HIV-1-infected adults Vaccine. 29: 9224-9228. PMID 21978767 DOI: 10.1016/J.Vaccine.2011.09.106  0.404
2011 Ozawa M, Kawaoka Y. Taming influenza viruses Virus Research. 162: 8-11. PMID 21968297 DOI: 10.1016/J.Virusres.2011.09.035  0.65
2011 Watanabe T, Shinya K, Watanabe S, Imai M, Hatta M, Li C, Wolter BF, Neumann G, Hanson A, Ozawa M, Yamada S, Imai H, Sakabe S, Takano R, Iwatsuki-Horimoto K, ... ... Kawaoka Y, et al. Avian-type receptor-binding ability can increase influenza virus pathogenicity in macaques. Journal of Virology. 85: 13195-203. PMID 21937653 DOI: 10.1128/Jvi.00859-11  0.6
2011 Ozawa M, Victor ST, Taft AS, Yamada S, Li C, Hatta M, Das SC, Takashita E, Kakugawa S, Maher EA, Neumann G, Kawaoka Y. Replication-incompetent influenza A viruses that stably express a foreign gene Journal of General Virology. 92: 2879-2888. PMID 21880840 DOI: 10.1099/Vir.0.037648-0  0.647
2011 Li C, Bankhead A, Eisfeld AJ, Hatta Y, Jeng S, Chang JH, Aicher LD, Proll S, Ellis AL, Law GL, Waters KM, Neumann G, Katze MG, McWeeney S, Kawaoka Y. Host regulatory network response to infection with highly pathogenic H5N1 avian influenza virus. Journal of Virology. 85: 10955-67. PMID 21865398 DOI: 10.1128/Jvi.05792-11  0.642
2011 Liu J, Chen P, Jiang Y, Wu L, Zeng X, Tian G, Ge J, Kawaoka Y, Bu Z, Chen H. A duck enteritis virus-vectored bivalent live vaccine provides fast and complete protection against H5N1 avian influenza virus infection in ducks. Journal of Virology. 85: 10989-98. PMID 21865383 DOI: 10.1128/Jvi.05420-11  0.632
2011 Fukuyama S, Kawaoka Y. The pathogenesis of influenza virus infections: The contributions of virus and host factors Current Opinion in Immunology. 23: 481-486. PMID 21840185 DOI: 10.1016/J.Coi.2011.07.016  0.678
2011 Sugita Y, Noda T, Sagara H, Kawaoka Y. Ultracentrifugation deforms unfixed influenza A virions. The Journal of General Virology. 92: 2485-93. PMID 21795472 DOI: 10.1099/Vir.0.036715-0  0.598
2011 Eisfeld AJ, Neumann G, Kawaoka Y. Human immunodeficiency virus rev-binding protein is essential for influenza a virus replication and promotes genome trafficking in late-stage infection Journal of Virology. 85: 9588-9598. PMID 21752912 DOI: 10.1128/Jvi.05064-11  0.654
2011 Cilloniz C, Ebihara H, Ni C, Neumann G, Korth MJ, Kelly SM, Kawaoka Y, Feldmann H, Katze MG. Functional genomics reveals the induction of inflammatory response and metalloproteinase gene expression during lethal Ebola virus infection. Journal of Virology. 85: 9060-8. PMID 21734050 DOI: 10.1128/Jvi.00659-11  0.543
2011 Yan P, Zhao Y, Zhang X, Xu D, Dai X, Teng Q, Yan L, Zhou J, Ji X, Zhang S, Liu G, Zhou Y, Kawaoka Y, Tong G, Li Z. An infectious disease of ducks caused by a newly emerged Tembusu virus strain in mainland China. Virology. 417: 1-8. PMID 21722935 DOI: 10.1016/J.Virol.2011.06.003  0.603
2011 Walsh KB, Teijaro JR, Wilker PR, Jatzek A, Fremgen DM, Das SC, Watanabe T, Hatta M, Shinya K, Suresh M, Kawaoka Y, Rosen H, Oldstone MB. Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus. Proceedings of the National Academy of Sciences of the United States of America. 108: 12018-23. PMID 21715659 DOI: 10.1073/Pnas.1107024108  0.633
2011 Yamaoka M, Palilingan JF, Wibisono J, Yudhawati R, Nidom RV, Alamudi MY, Ginting TE, Makino A, Nidom CA, Shinya K, Kawaoka Y. Virological surveillance of human influenza in Indonesia, October 2008-March 2010 Microbiology and Immunology. 55: 514-517. PMID 21707740 DOI: 10.1111/J.1348-0421.2011.00344.X  0.649
2011 Poetranto ED, Yamaoka M, Nastri AM, Krisna LA, Rahman MH, Wulandari L, Yudhawati R, Ginting TE, Makino A, Shinya K, Kawaoka Y. An H5N1 highly pathogenic avian influenza virus isolated from a local tree sparrow in Indonesia. Microbiology and Immunology. 55: 666-72. PMID 21699556 DOI: 10.1111/J.1348-0421.2011.00361.X  0.652
2011 Octaviani CP, Goto H, Kawaoka Y. Reassortment between seasonal H1N1 and pandemic (H1N1) 2009 influenza viruses is restricted by limited compatibility among polymerase subunits Journal of Virology. 85: 8449-8452. PMID 21680507 DOI: 10.1128/Jvi.05054-11  0.675
2011 Morlighem JÉ, Aoki S, Kishima M, Hanami M, Ogawa C, Jalloh A, Takahashi Y, Kawai Y, Saga S, Hayashi E, Ban T, Izumi S, Wada A, Mano M, Fukunaga M, ... ... Kawaoka Y, et al. Mutation analysis of 2009 pandemic influenza A(H1N1) viruses collected in Japan during the peak phase of the pandemic. Plos One. 6: e18956. PMID 21572517 DOI: 10.1371/Journal.Pone.0018956  0.626
2011 Eisfeld AJ, Kawakami E, Watanabe T, Neumann G, Kawaoka Y. RAB11A is essential for transport of the influenza virus genome to the plasma membrane Journal of Virology. 85: 6117-6126. PMID 21525351 DOI: 10.1128/Jvi.00378-11  0.486
2011 Neumann G, Kawaoka Y. The first influenza pandemic of the new millennium Influenza and Other Respiratory Viruses. 5: 157-166. PMID 21477134 DOI: 10.1111/J.1750-2659.2011.00231.X  0.677
2011 Shimizu K, Li C, Muramoto Y, Yamada S, Arikawa J, Chen H, Kawaoka Y. The nucleoprotein and matrix protein segments of H5N1 influenza viruses are responsible for dominance in embryonated eggs Journal of General Virology. 92: 1645-1649. PMID 21471324 DOI: 10.1099/Vir.0.030247-0  0.657
2011 Horimoto T, Maeda K, Murakami S, Kiso M, Iwatsuki-Horimoto K, Sashika M, Ito T, Suzuki K, Yokoyama M, Kawaoka Y. Highly pathogenic avian influenza virus infection in feral Raccoons, Japan Emerging Infectious Diseases. 17: 714-717. PMID 21470469 DOI: 10.3201/Eid1704.101604  0.675
2011 Sakabe S, Ozawa M, Takano R, Iwastuki-Horimoto K, Kawaoka Y. Mutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice Virus Research. 158: 124-129. PMID 21458512 DOI: 10.1016/J.Virusres.2011.03.022  0.64
2011 Tomita Y, Noda T, Fujii K, Watanabe T, Morikawa Y, Kawaoka Y. The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles Journal of Virology. 85: 5618-5627. PMID 21450827 DOI: 10.1128/Jvi.00846-10  0.306
2011 Shinya K, Makino A, Tanaka H, Hatta M, Watanabe T, Le MQ, Imai H, Kawaoka Y. Systemic dissemination of H5N1 influenza a viruses in ferrets and hamsters after direct intragastric inoculation Journal of Virology. 85: 4673-4678. PMID 21411541 DOI: 10.1128/Jvi.00148-11  0.611
2011 Shinya K, Makino A, Hatta M, Watanabe S, Kim JH, Hatta Y, Gao P, Ozawa M, Le QM, Kawaoka Y. Subclinical brain injury caused by H5N1 influenza virus infection. Journal of Virology. 85: 5202-7. PMID 21389133 DOI: 10.1128/Jvi.00239-11  0.579
2011 Shinya K, Okamura T, Sueta S, Kasai N, Tanaka M, Ginting TE, Makino A, Eisfeld AJ, Kawaoka Y. Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses. Virology Journal. 8: 97. PMID 21375734 DOI: 10.1186/1743-422X-8-97  0.668
2011 Sakabe S, Iwatsuki-Horimoto K, Takano R, Nidom CA, Le Mt, Nagamura-Inoue T, Horimoto T, Yamashita N, Kawaoka Y. Cytokine production by primary human macrophages infected with highly pathogenic H5N1 or pandemic H1N1 2009 influenza viruses. The Journal of General Virology. 92: 1428-34. PMID 21367984 DOI: 10.1099/Vir.0.030346-0  0.634
2011 Kiso M, Ozawa M, Le MT, Imai H, Takahashi K, Kakugawa S, Noda T, Horimoto T, Kawaoka Y. Effect of an asparagine-to-serine mutation at position 294 in neuraminidase on the pathogenicity of highly pathogenic H5N1 influenza A virus. Journal of Virology. 85: 4667-72. PMID 21367898 DOI: 10.1128/Jvi.00047-11  0.58
2011 Iwatsuki-Horimoto K, Horimoto T, Tamura D, Kiso M, Kawakami E, Hatakeyama S, Ebihara Y, Koibuchi T, Fujii T, Takahashi K, Shimojima M, Sakai-Tagawa Y, Ito M, Sakabe S, Iwasa A, ... ... Kawaoka Y, et al. Seroprevalence of pandemic 2009 (H1N1) influenza A virus among schoolchildren and their parents in Tokyo, Japan Clinical and Vaccine Immunology. 18: 860-866. PMID 21346056 DOI: 10.1128/Cvi.00428-10  0.603
2011 Ozawa M, Basnet S, Burley LM, Neumann G, Hatta M, Kawaoka Y. Impact of amino acid mutations in PB2, PB1-F2, and NS1 on the replication and pathogenicity of pandemic (H1N1) 2009 influenza viruses Journal of Virology. 85: 4596-4601. PMID 21325408 DOI: 10.1128/Jvi.00029-11  0.589
2011 Watanabe T, Kawaoka Y. Pathogenesis of the 1918 Pandemic Influenza Virus Plos Pathogens. 7. PMID 21298032 DOI: 10.1371/Journal.Ppat.1001218  0.568
2011 Hatta Y, Hatta M, Bilsel P, Neumann G, Kawaoka Y. An M2 cytoplasmic tail mutant as a live attenuated influenza vaccine against pandemic (H1N1) 2009 influenza virus. Vaccine. 29: 2308-2312. PMID 21272601 DOI: 10.1016/J.Vaccine.2011.01.023  0.649
2011 Tamura D, Sugaya N, Ozawa M, Takano R, Ichikawa M, Yamazaki M, Kawakami C, Shimizu H, Uehara R, Kiso M, Kawakami E, Mitamura K, Kawaoka Y. Frequency of drug-resistant viruses and virus shedding in pediatric influenza patients treated with neuraminidase inhibitors. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 52: 432-7. PMID 21248368 DOI: 10.1093/Cid/Ciq183  0.587
2011 Shtanko O, Watanabe S, Jasenosky LD, Watanabe T, Kawaoka Y. ALIX/AIP1 Is Required for NP Incorporation into Mopeia Virus Z-Induced Virus-Like Particles Journal of Virology. 85: 3631-3641. PMID 21248028 DOI: 10.1128/Jvi.01984-10  0.504
2011 Octaviani CP, Li C, Noda T, Kawaoka Y. Reassortment between seasonal and swine-origin H1N1 influenza viruses generates viruses with enhanced growth capability in cell culture. Virus Research. 156: 147-150. PMID 21195732 DOI: 10.1016/J.Virusres.2010.12.014  0.647
2011 Kawakami E, Watanabe T, Fujii K, Goto H, Watanabe S, Noda T, Kawaoka Y. Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA Journal of Virological Methods. 173: 1-6. PMID 21185869 DOI: 10.1016/J.Jviromet.2010.12.014  0.466
2011 Song J, Feng H, Xu J, Zhao D, Shi J, Li Y, Deng G, Jiang Y, Li X, Zhu P, Guan Y, Bu Z, Kawaoka Y, Chen H. The PA protein directly contributes to the virulence of H5N1 avian influenza viruses in domestic ducks. Journal of Virology. 85: 2180-8. PMID 21177821 DOI: 10.1128/Jvi.01975-10  0.632
2011 Watanabe T, Sakurai A, Kawaoka Y. [Identification of host factors involved in influenza virus replication]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 54: 920-5. PMID 21089518  0.569
2011 Shinya K, Yamada S, Kawaoka Y. [Receptor specificity of influenza viruses]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 53: 1520-4. PMID 21089359  0.497
2011 Safronetz D, Rockx B, Feldmann F, Belisle SE, Palermo RE, Brining D, Gardner D, Proll SC, Marzi A, Tsuda Y, Lacasse RA, Kercher L, York A, Korth MJ, Long D, ... ... Kawaoka Y, et al. Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques. Journal of Virology. 85: 1214-23. PMID 21084481 DOI: 10.1128/Jvi.01848-10  0.665
2011 Shiozaki T, Iwai A, Kawaoka Y, Takada A, Kida H, Miyazaki T. Requirement for Siva-1 for replication of influenza A virus through apoptosis induction. The Journal of General Virology. 92: 315-25. PMID 21048035 DOI: 10.1099/Vir.0.028316-0  0.653
2011 Akarsu H, Iwatsuki-Horimoto K, Noda T, Kawakami E, Katsura H, Baudin F, Horimoto T, Kawaoka Y. Structure-based design of NS2 mutants for attenuated influenza A virus vaccines. Virus Research. 155: 240-8. PMID 20970464 DOI: 10.1016/J.Virusres.2010.10.014  0.55
2011 Hatakeyama S, Ozawa M, Kawaoka Y. In vitro selection of influenza B viruses with reduced sensitivity to neuraminidase inhibitors Clinical Microbiology and Infection. 17: 1332-1335. PMID 20636420 DOI: 10.1111/J.1469-0691.2010.03313.X  0.517
2010 Takahashi T, Kurebayashi Y, Ikeya K, Mizuno T, Fukushima K, Kawamoto H, Kawaoka Y, Suzuki Y, Suzuki T. The low-pH stability discovered in neuraminidase of 1918 pandemic influenza A virus enhances virus replication. Plos One. 5. PMID 21151571 DOI: 10.1371/Journal.Pone.0015556  0.572
2010 Haraguchi H, Sudo S, Noda T, Momose F, Kawaoka Y, Morikawa Y. Intracellular localization of human immunodeficiency virus type 1 Gag and GagPol products and virus particle release: relationship with the Gag-to-GagPol ratio. Microbiology and Immunology. 54: 734-46. PMID 21091985 DOI: 10.1111/J.1348-0421.2010.00276.X  0.429
2010 Kuhn JH, Becker S, Ebihara H, Geisbert TW, Johnson KM, Kawaoka Y, Lipkin WI, Negredo AI, Netesov SV, Nichol ST, Palacios G, Peters CJ, Tenorio A, Volchkov VE, Jahrling PB. Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations. Archives of Virology. 155: 2083-103. PMID 21046175 DOI: 10.1007/S00705-010-0814-X  0.598
2010 Hatta Y, Hershberger K, Shinya K, Proll SC, Dubielzig RR, Hatta M, Katze MG, Kawaoka Y, Suresh M. Viral replication rate regulates clinical outcome and CD8 T cell responses during highly pathogenic H5N1 influenza virus infection in mice. Plos Pathogens. 6: e1001139. PMID 20949022 DOI: 10.1371/Journal.Ppat.1001139  0.612
2010 Arii J, Goto H, Suenaga T, Oyama M, Kozuka-Hata H, Imai T, Minowa A, Akashi H, Arase H, Kawaoka Y, Kawaguchi Y. Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus-1. Nature. 467: 859-62. PMID 20944748 DOI: 10.1038/Nature09420  0.443
2010 Nanbo A, Imai M, Watanabe S, Noda T, Takahashi K, Neumann G, Halfmann P, Kawaoka Y. Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. Plos Pathogens. 6. PMID 20886108 DOI: 10.1371/Journal.Ppat.1001121  0.44
2010 Nidom CA, Takano R, Yamada S, Sakai-Tagawa Y, Daulay S, Aswadi D, Suzuki T, Suzuki Y, Shinya K, Iwatsuki-Horimoto K, Muramoto Y, Kawaoka Y. Influenza A (H5N1) Viruses from Pigs, Indonesia Emerging Infectious Diseases. 16: 1515-1523. PMID 20875275 DOI: 10.3201/Eid1610.100508  0.682
2010 Kiso M, Shinya K, Shimojima M, Takano R, Takahashi K, Katsura H, Kakugawa S, Le MT, Yamashita M, Furuta Y, Ozawa M, Kawaoka Y. Characterization of oseltamivir-resistant 2009 H1N1 pandemic influenza A viruses. Plos Pathogens. 6: e1001079. PMID 20865125 DOI: 10.1371/Journal.Ppat.1001079  0.602
2010 Imai H, Shinya K, Takano R, Kiso M, Muramoto Y, Sakabe S, Murakami S, Ito M, Yamada S, Le MT, Nidom CA, Sakai-Tagawa Y, Takahashi K, Omori Y, Noda T, ... ... Kawaoka Y, et al. The HA and NS genes of human H5N1 influenza A virus contribute to high virulence in ferrets. Plos Pathogens. 6: e1001106. PMID 20862325 DOI: 10.1371/Journal.Ppat.1001106  0.676
2010 Noda T, Kawaoka Y. Structure of influenza virus ribonucleoprotein complexes and their packaging into virions. Reviews in Medical Virology. 20: 380-391. PMID 20853340 DOI: 10.1002/Rmv.666  0.492
2010 Sakabe S, Iwatsuki-Horimoto K, Horimoto T, Nidom CA, Le Mt, Takano R, Kubota-Koketsu R, Okuno Y, Ozawa M, Kawaoka Y. A cross-reactive neutralizing monoclonal antibody protects mice from H5N1 and pandemic (H1N1) 2009 virus infection. Antiviral Research. 88: 249-55. PMID 20849879 DOI: 10.1016/J.Antiviral.2010.09.007  0.649
2010 Horimoto T, Yamada S, Kawaoka Y. Virological characteristics of pandemic (H1N1) 2009 influenza virus Uirusu. 60: 3-8. PMID 20848859 DOI: 10.2222/Jsv.60.3  0.682
2010 Horimoto T, Yamada S, Kawaoka Y. [Transmissibility and pathogenicity of influenza viruses]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 68: 1616-23. PMID 20845737  0.601
2010 Noda T, Kawaoka Y. [Mechanisms of influenza virus replication]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 68: 1611-5. PMID 20845736  0.483
2010 Noda T, Kawaoka Y. [Genetic and molecular characteristics of the 2009 H1N1 pandemic influenza A virus]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 68: 1590-3. PMID 20845732  0.563
2010 Yamada S, Hatta M, Staker BL, Watanabe S, Imai M, Shinya K, Sakai-Tagawa Y, Ito M, Ozawa M, Watanabe T, Sakabe S, Li C, Kim JH, Myler PJ, Phan I, ... ... Kawaoka Y, et al. Biological and structural characterization of a host-adapting amino acid in influenza virus. Plos Pathogens. 6: e1001034. PMID 20700447 DOI: 10.1371/Journal.Ppat.1001034  0.62
2010 Iwai A, Shiozaki T, Kawai T, Akira S, Kawaoka Y, Takada A, Kida H, Miyazaki T. Influenza A virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1. The Journal of Biological Chemistry. 285: 32064-74. PMID 20699220 DOI: 10.1074/Jbc.M110.112458  0.616
2010 Octaviani CP, Ozawa M, Yamada S, Goto H, Kawaoka Y. High level of genetic compatibility between swine-origin H1N1 and highly pathogenic avian H5N1 influenza viruses. Journal of Virology. 84: 10918-10922. PMID 20686037 DOI: 10.1128/Jvi.01140-10  0.668
2010 Grandea AG, Olsen OA, Cox TC, Renshaw M, Hammond PW, Chan-Hui PY, Mitcham JL, Cieplak W, Stewart SM, Grantham ML, Pekosz A, Kiso M, Shinya K, Hatta M, Kawaoka Y, et al. Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses. Proceedings of the National Academy of Sciences of the United States of America. 107: 12658-63. PMID 20615945 DOI: 10.1073/Pnas.0911806107  0.607
2010 Le QM, Ito M, Muramoto Y, Hoang PV, Vuong CD, Sakai-Tagawa Y, Kiso M, Ozawa M, Takano R, Kawaoka Y. Pathogenicity of highly pathogenic avian H5N1 influenza A viruses isolated from humans between 2003 and 2008 in northern Vietnam. The Journal of General Virology. 91: 2485-90. PMID 20592108 DOI: 10.1099/Vir.0.021659-0  0.607
2010 Chen Y, Zhong G, Wang G, Deng G, Li Y, Shi J, Zhang Z, Guan Y, Jiang Y, Bu Z, Kawaoka Y, Chen H. Dogs are highly susceptible to H5N1 avian influenza virus. Virology. 405: 15-9. PMID 20580396 DOI: 10.1016/J.Virol.2010.05.024  0.617
2010 Sakai-Tagawa Y, Ozawa M, Tamura D, Le Mt, Nidom CA, Sugaya N, Kawaoka Y. Sensitivity of influenza rapid diagnostic tests to H5N1 and 2009 pandemic H1N1 viruses. Journal of Clinical Microbiology. 48: 2872-7. PMID 20554831 DOI: 10.1128/Jcm.00439-10  0.659
2010 Watanabe T, Watanabe S, Kawaoka Y. Cellular Networks Involved in the Influenza Virus Life Cycle Cell Host & Microbe. 7: 427-439. PMID 20542247 DOI: 10.1016/J.Chom.2010.05.008  0.642
2010 Monteerarat Y, Sakabe S, Ngamurulert S, Srichatraphimuk S, Jiamtom W, Chaichuen K, Thitithanyanont A, Permpikul P, Songserm T, Puthavathana P, Nidom CA, Mai LQ, Iwatsuki-Horimoto K, Kawaoka Y, Auewarakul P. Induction of TNF-α in human macrophages by avian and human influenza viruses Archives of Virology. 155: 1273-1279. PMID 20532927 DOI: 10.1007/S00705-010-0716-Y  0.522
2010 Tamura D, Fujino M, Ozawa M, Iwatsuki-Horimoto K, Goto H, Sakai-Tagawa Y, Horimoto T, Nirasawa M, Kawaoka Y. Significance of seasonal influenza viruses in the stool of pediatric patients. Pediatric Infectious Disease Journal. 29: 578-579. PMID 20508482 DOI: 10.1097/Inf.0B013E3181Dab225  0.593
2010 Jasenosky LD, Neumann G, Kawaoka Y. Minigenome-Based Reporter System Suitable for High-Throughput Screening of Compounds Able To Inhibit Ebolavirus Replication and/or Transcription Antimicrobial Agents and Chemotherapy. 54: 3007-3010. PMID 20421407 DOI: 10.1128/Aac.00138-10  0.307
2010 Matsuno K, Kishida N, Usami K, Igarashi M, Yoshida R, Nakayama E, Shimojima M, Feldmann H, Irimura T, Kawaoka Y, Takada A. Different Potential of C-Type Lectin-Mediated Entry between Marburg Virus Strains Journal of Virology. 84: 5140-5147. PMID 20219911 DOI: 10.1128/Jvi.02021-09  0.437
2010 Shtanko O, Imai M, Goto H, Lukashevich IS, Neumann G, Watanabe T, Kawaoka Y. A role for the C terminus of Mopeia virus nucleoprotein in its incorporation into Z protein-induced virus-like particles. Journal of Virology. 84: 5415-22. PMID 20200234 DOI: 10.1128/Jvi.02417-09  0.481
2010 Kiso M, Kubo S, Ozawa M, Le QM, Nidom CA, Yamashita M, Kawaoka Y. Efficacy of the new neuraminidase inhibitor CS-8958 against H5N1 influenza viruses. Plos Pathogens. 6: e1000786. PMID 20195462 DOI: 10.1371/Journal.Ppat.1000786  0.633
2010 Li C, Hatta M, Nidom CA, Muramoto Y, Watanabe S, Neumann G, Kawaoka Y. Reassortment between avian H5N1 and human H3N2 influenza viruses creates hybrid viruses with substantial virulence Proceedings of the National Academy of Sciences of the United States of America. 107: 4687-4692. PMID 20176961 DOI: 10.1073/Pnas.0912807107  0.689
2010 Noda T, Hagiwara K, Sagara H, Kawaoka Y. Characterization of the Ebola virus nucleoprotein-RNA complex. Journal of General Virology. 91: 1478-1483. PMID 20164259 DOI: 10.1099/Vir.0.019794-0  0.413
2010 Shinya K, Makino A, Hatta M, Watanabe S, Kim JH, Kawaoka Y. A mutation in H5 haemagglutinin that conferred human receptor recognition is not maintained stably during duck passage. The Journal of General Virology. 91: 1461-3. PMID 20130132 DOI: 10.1099/Vir.0.018572-0  0.505
2010 Kiso M, Takahashi K, Sakai-Tagawa Y, Shinya K, Sakabe S, Le QM, Ozawa M, Furuta Y, Kawaoka Y. T-705 (favipiravir) activity against lethal H5N1 influenza A viruses. Proceedings of the National Academy of Sciences of the United States of America. 107: 882-887. PMID 20080770 DOI: 10.1073/Pnas.0909603107  0.651
2010 Shinya K, Makino A, Kawaoka Y. Emerging and Reemerging Influenza Virus Infections Veterinary Pathology. 47: 53-57. PMID 20080485 DOI: 10.1177/0300985809354464  0.667
2010 Kim JH, Hatta M, Watanabe S, Neumann G, Watanabe T, Kawaoka Y. Role of host-specific amino acids in the pathogenicity of avian H5N1 influenza viruses in mice. The Journal of General Virology. 91: 1284-9. PMID 20016035 DOI: 10.1099/Vir.0.018143-0  0.628
2010 Neumann G, Chen H, Gao GF, Shu Y, Kawaoka Y. H5N1 influenza viruses: outbreaks and biological properties Cell Research. 20: 51-61. PMID 19884910 DOI: 10.1038/Cr.2009.124  0.675
2010 Horimoto T, Kawaoka Y. Pandemic Influenza~!2010-01-17~!2010-04-05~!2010-08-27~! The Open Antimicrobial Agents Journal. 2: 9-14. DOI: 10.2174/1876518101002020009  0.612
2009 Gao Y, Zhang Y, Shinya K, Deng G, Jiang Y, Li Z, Guan Y, Tian G, Li Y, Shi J, Liu L, Zeng X, Bu Z, Xia X, Kawaoka Y, et al. Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host. Plos Pathogens. 5: e1000709. PMID 20041223 DOI: 10.1371/Journal.Ppat.1000709  0.639
2009 Cillóniz C, Shinya K, Peng X, Korth MJ, Proll SC, Aicher LD, Carter VS, Chang JH, Kobasa D, Feldmann F, Strong JE, Feldmann H, Kawaoka Y, Katze MG. Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes. Plos Pathogens. 5: e1000604. PMID 19798428 DOI: 10.1371/Journal.Ppat.1000604  0.626
2009 Shinya K, Makino A, Ozawa M, Kim JH, Sakai-Tagawa Y, Ito M, Le QM, Kawaoka Y. Ostrich involvement in the selection of H5N1 influenza virus possessing mammalian-type amino acids in the PB2 protein. Journal of Virology. 83: 13015-8. PMID 19793811 DOI: 10.1128/Jvi.01714-09  0.649
2009 Horimoto T, Kawaoka Y. Designing vaccines for pandemic influenza. Current Topics in Microbiology and Immunology. 333: 165-176. PMID 19768405 DOI: 10.1007/978-3-540-92165-3_8  0.537
2009 Kashima Y, Ikeda M, Itoh Y, Sakoda Y, Nagata T, Miyake T, Soda K, Ozaki H, Nakayama M, Shibuya H, Okamatsu M, Ishigaki H, Ishida H, Sawai T, Kawaoka Y, et al. Intranasal administration of a live non-pathogenic avian H5N1 influenza virus from a virus library confers protective immunity against H5N1 highly pathogenic avian influenza virus infection in mice: comparison of formulations and administration routes of vaccines. Vaccine. 27: 7402-7408. PMID 19747993 DOI: 10.1016/J.Vaccine.2009.08.089  0.609
2009 Takahashi T, Hashimoto A, Maruyama M, Ishida H, Kiso M, Kawaoka Y, Suzuki Y, Suzuki T. Identification of amino acid residues of influenza A virus H3 HA contributing to the recognition of molecular species of sialic acid Febs Letters. 583: 3171-3174. PMID 19720062 DOI: 10.1016/J.Febslet.2009.08.037  0.492
2009 Itoh Y, Shinya K, Kiso M, Watanabe T, Sakoda Y, Hatta M, Muramoto Y, Tamura D, Sakai-Tagawa Y, Noda T, Sakabe S, Imai M, Hatta Y, Watanabe S, Li C, ... ... Kawaoka Y, et al. In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature. 460: 1021-5. PMID 19672242 DOI: 10.1038/Nature08260  0.622
2009 Zhou B, Donnelly ME, Scholes DT, George KS, Hatta M, Kawaoka Y, Wentworth DE. Single-Reaction Genomic Amplification Accelerates Sequencing and Vaccine Production for Classical and Swine Origin Human Influenza A Viruses Journal of Virology. 83: 10309-10313. PMID 19605485 DOI: 10.1128/Jvi.01109-09  0.575
2009 Neumann G, Noda T, Kawaoka Y. Emergence and pandemic potential of swine-origin H1N1 influenza virus. Nature. 459: 931-939. PMID 19525932 DOI: 10.1038/Nature08157  0.65
2009 Donis RO, Smith G, Brown IH, Capua I, Cattoli G, Chen H, Cox N, Davis CT, Fouchier RAM, Garten R, Guan Y, Hay A, Kawaoka Y, Mackenzie J, McCauley J, et al. Continuing progress towards a unified nomenclature for the highly pathogenic H5N1 avian influenza viruses: Divergence of clade 2·2 viruses Influenza and Other Respiratory Viruses. 3: 59-62. PMID 19496842 DOI: 10.1111/J.1750-2659.2009.00078.X  0.562
2009 Takano R, Nidom CA, Kiso M, Muramoto Y, Yamada S, Sakai-Tagawa Y, Macken C, Kawaoka Y. Phylogenetic characterization of H5N1 avian influenza viruses isolated in Indonesia from 2003–2007 Virology. 390: 13-21. PMID 19464724 DOI: 10.1016/J.Virol.2009.04.024  0.667
2009 Makino A, Kawaoka Y. Generation of Vero Cells Expressing Ebola Virus Glycoprotein Journal of Veterinary Medical Science. 71: 505-507. PMID 19420858 DOI: 10.1292/Jvms.71.505  0.455
2009 Fan S, Gao Y, Shinya K, Li CK, Li Y, Shi J, Jiang Y, Suo Y, Tong T, Zhong G, Song J, Zhang Y, Tian G, Guan Y, Xu XN, ... ... Kawaoka Y, et al. Immunogenicity and protective efficacy of a live attenuated H5N1 vaccine in nonhuman primates. Plos Pathogens. 5: e1000409. PMID 19412338 DOI: 10.1371/Journal.Ppat.1000409  0.62
2009 Kakugawa S, Shimojima M, Neumann G, Goto H, Kawaoka Y. RuvB-Like Protein 2 Is a Suppressor of Influenza A Virus Polymerases Journal of Virology. 83: 6429-6434. PMID 19369355 DOI: 10.1128/Jvi.00293-09  0.648
2009 Watanabe S, Watanabe T, Kawaoka Y. Influenza A Virus Lacking M2 Protein as a Live Attenuated Vaccine Journal of Virology. 83: 5947-5950. PMID 19321619 DOI: 10.1128/Jvi.00450-09  0.605
2009 Fujii K, Ozawa M, Iwatsuki-Horimoto K, Horimoto T, Kawaoka Y. Incorporation of influenza A virus genome segments does not absolutely require wild-type sequences. Journal of General Virology. 90: 1734-1740. PMID 19297607 DOI: 10.1099/Vir.0.010355-0  0.54
2009 Takano R, Nidom CA, Kiso M, Muramoto Y, Yamada S, Shinya K, Sakai-Tagawa Y, Kawaoka Y. A comparison of the pathogenicity of avian and swine H5N1 influenza viruses in Indonesia. Archives of Virology. 154: 677-681. PMID 19288052 DOI: 10.1007/S00705-009-0353-5  0.655
2009 Hatta M, Kohlmeier CK, Hatta Y, Ozawa M, Kawaoka Y. Region required for protein expression from the stop-start pentanucleotide in the M gene of influenza B virus. Journal of Virology. 83: 5939-5942. PMID 19279094 DOI: 10.1128/Jvi.00180-09  0.408
2009 Le QM, Sakai-Tagawa Y, Ozawa M, Ito M, Kawaoka Y. Selection of H5N1 Influenza Virus PB2 during Replication in Humans Journal of Virology. 83: 5278-5281. PMID 19264775 DOI: 10.1128/Jvi.00063-09  0.641
2009 Makino A, Horimoto T, Kawaoka Y. Binding properties of GP1 protein of Borna disease virus. Journal of Veterinary Medical Science. 71: 243-246. PMID 19262042 DOI: 10.1292/Jvms.71.243  0.401
2009 Tamura D, Mitamura K, Yamazaki M, Fujino M, Nirasawa M, Kimura K, Kiso M, Shimizu H, Kawakami C, Hiroi S, Takahashi K, Hata M, Minagawa H, Kimura Y, Kaneda S, ... ... Kawaoka Y, et al. Oseltamivir-resistant influenza a viruses circulating in Japan. Journal of Clinical Microbiology. 47: 1424-7. PMID 19261802 DOI: 10.1128/Jcm.02396-08  0.57
2009 Li Z, Watanabe T, Hatta M, Watanabe S, Nanbo A, Ozawa M, Kakugawa S, Shimojima M, Yamada S, Neumann G, Kawaoka Y. Mutational analysis of conserved amino acids in the influenza A virus nucleoprotein. Journal of Virology. 83: 4153-62. PMID 19225007 DOI: 10.1128/Jvi.02642-08  0.482
2009 Halfmann P, Ebihara H, Marzi A, Hatta Y, Watanabe S, Suresh M, Neumann G, Feldmann H, Kawaoka Y. Replication-deficient ebolavirus as a vaccine candidate. Journal of Virology. 83: 3810-3815. PMID 19211761 DOI: 10.1128/Jvi.00074-09  0.536
2009 Marsolais D, Hahm B, Walsh KB, Edelmann KH, McGavern D, Hatta Y, Kawaoka Y, Rosen H, Oldstone MB. A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection. Proceedings of the National Academy of Sciences of the United States of America. 106: 1560-5. PMID 19164548 DOI: 10.1073/Pnas.0812689106  0.523
2009 Ozawa M, Maeda J, Iwatsuki-Horimoto K, Watanabe S, Goto H, Horimoto T, Kawaoka Y. Nucleotide Sequence Requirements at the 5′ End of the Influenza A Virus M RNA Segment for Efficient Virus Replication Journal of Virology. 83: 3384-3388. PMID 19158245 DOI: 10.1128/Jvi.02513-08  0.469
2009 Kakugawa S, Shimojima M, Goto H, Horimoto T, Oshimori N, Neumann G, Yamamoto T, Kawaoka Y. Mitogen-Activated Protein Kinase-Activated Kinase RSK2 Plays a Role in Innate Immune Responses to Influenza Virus Infection Journal of Virology. 83: 2510-2517. PMID 19129453 DOI: 10.1128/Jvi.02416-08  0.525
2009 Fan S, Deng G, Song J, Tian G, Suo Y, Jiang Y, Guan Y, Bu Z, Kawaoka Y, Chen H. Two amino acid residues in the matrix protein M1 contribute to the virulence difference of H5N1 avian influenza viruses in mice. Virology. 384: 28-32. PMID 19117585 DOI: 10.1016/J.Virol.2008.11.044  0.591
2009 Watanabe T, Watanabe S, Shinya K, Kim JH, Hatta M, Kawaoka Y. Viral RNA polymerase complex promotes optimal growth of 1918 virus in the lower respiratory tract of ferrets. Proceedings of the National Academy of Sciences of the United States of America. 106: 588-92. PMID 19114663 DOI: 10.1073/Pnas.0806959106  0.665
2009 Sakuma T, Noda T, Urata S, Kawaoka Y, Yasuda J. Inhibition of Lassa and Marburg Virus Production by Tetherin Journal of Virology. 83: 2382-2385. PMID 19091864 DOI: 10.1128/Jvi.01607-08  0.581
2009 Murakami S, Horimoto T, Kawaoka Y. Construction and application of the recombinant influenza viruses Drug Delivery System. 24: 616-626. DOI: 10.2745/Dds.24.616  0.624
2008 Wit Ed, Kawaoka Y, Jong MDd, Fouchier RAM. Pathogenicity of highly pathogenic avian influenza virus in mammals Vaccine. 26. PMID 19230161 DOI: 10.1016/J.Vaccine.2008.07.072  0.668
2008 Horimoto T, Murakami S, Kawaoka Y. [Influenza vaccine]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 66: 2013-8. PMID 18939506  0.361
2008 Li C, Hatta M, Watanabe S, Neumann G, Kawaoka Y. Compatibility among Polymerase Subunit Proteins Is a Restricting Factor in Reassortment between Equine H7N7 and Human H3N2 Influenza Viruses Journal of Virology. 82: 11880-11888. PMID 18815312 DOI: 10.1128/Jvi.01445-08  0.632
2008 Murakami S, Iwasa A, Iwatsuki-Horimoto K, Ito M, Kiso M, Kida H, Takada A, Nidom CA, Mai LQ, Yamada S, Imai H, Sakai-Tagawa Y, Kawaoka Y, Horimoto T. Cross-clade protective immunity of H5N1 influenza vaccines in a mouse model Vaccine. 26: 6398-6404. PMID 18804131 DOI: 10.1016/J.Vaccine.2008.08.053  0.466
2008 Jia B, Shi J, Li Y, Shinya K, Muramoto Y, Zeng X, Tian G, Kawaoka Y, Chen H. Pathogenicity of Chinese H5N1 highly pathogenic avian influenza viruses in pigeons. Archives of Virology. 153: 1821-6. PMID 18779923 DOI: 10.1007/S00705-008-0193-8  0.658
2008 Murakami S, Horimoto T, Le QM, Nidom CA, Chen H, Muramoto Y, Yamada S, Iwasa A, Iwatsuki-Horimoto K, Shimojima M, Iwata A, Kawaoka Y. Growth determinants for H5N1 influenza vaccine seed viruses in MDCK cells Journal of Virology. 82: 10502-10509. PMID 18768983 DOI: 10.1128/Jvi.00970-08  0.621
2008 Hao L, Sakurai A, Watanabe T, Sorensen E, Nidom CA, Newton MA, Ahlquist P, Kawaoka Y. Drosophila RNAi screen identifies host genes important for influenza virus replication. Nature. 454: 890-3. PMID 18615016 DOI: 10.1038/Nature07151  0.666
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