David A. Largaespada - Publications

Affiliations: 
Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Molecular Biology, Virology Biology, Microbiology Biology

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Conboy CB, Vélez-Reyes GL, Tschida BR, Hu H, Kaufmann G, Koes N, Keller B, Alsinet C, Cornellà H, Pinyol R, Abrahante JE, Temiz NA, Linden MA, Amin K, Kuka TP, ... ... Largaespada DA, et al. R-spondin 2 Drives Liver Tumor Development in a Yes-Associated Protein-Dependent Manner. Hepatology Communications. 3: 1496-1509. PMID 31701073 DOI: 10.1002/hep4.1422  0.44
2019 Xiong Z, Ampudia Mesias E, Pluhar GE, Rathe SK, Largaespada DA, Sham YY, Moertel CL, Olin MR. CD200 Checkpoint Reversal:A Novel Approach to Immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31624103 DOI: 10.1158/1078-0432.CCR-19-2234  0.84
2019 Smeester BA, Slipek NJ, Pomeroy EJ, Bomberger HE, Shamsan GA, Peterson JJ, Crosby MR, Draper GM, Becklin KL, Rahrmann EP, McCarthy JB, Odde DJ, Wood DK, Largaespada DA, Moriarity BS. SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis. Oncogene. PMID 31582836 DOI: 10.1038/s41388-019-1041-x  0.84
2019 Huang M, Tailor J, Zhen Q, Gillmor AH, Miller ML, Weishaupt H, Chen J, Zheng T, Nash EK, McHenry LK, An Z, Ye F, Takashima Y, Clarke J, Ayetey H, ... ... Largaespada DA, et al. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. PMID 31204176 DOI: 10.1016/j.stem.2019.05.013  0.76
2019 Diessner BJ, Marko TA, Scott RM, Eckert AL, Stuebner KM, Hohenhaus AE, Selting KA, Largaespada DA, Modiano JF, Spector LG. A comparison of risk factors for metastasis at diagnosis in humans and dogs with osteosarcoma. Cancer Medicine. PMID 31006987 DOI: 10.1002/cam4.2177  0.6
2019 Chiu AP, Tschida BR, Sham TT, Lo LH, Moriarity BS, Li XX, Lo RC, Hinton DE, Rowlands DK, Chan CO, Mok DK, Largaespada DA, Warner N, Keng VW. HBx-K130M/V131I promotes liver cancer in transgenic mice via AKT/FOXO1 signaling pathway and arachidonic acid metabolism. Molecular Cancer Research : McR. PMID 30975706 DOI: 10.1158/1541-7786.MCR-18-1127  0.76
2019 Ramkissoon A, Chaney KE, Milewski D, Williams KB, Williams RL, Choi K, Miller AA, Kalin TV, Pressey JG, Szabo S, Azam M, Largaespada DA, Ratner N. Targeted inhibition of the dual specificity phosphatases DUSP1 and DUSP6 suppress MPNST growth via JNK. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30936125 DOI: 10.1158/1078-0432.CCR-18-3224  0.52
2019 Rathe SK, Popescu FE, Johnson JE, Watson AL, Marko TA, Moriarity BS, Ohlfest JR, Largaespada DA. Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas. Scientific Reports. 9: 358. PMID 30674975 DOI: 10.1038/s41598-018-36840-z  0.84
2019 Beckmann PJ, Larson JD, Larsson AT, Ostergaard JP, Wagner S, Rahrmann EP, Shamsan GA, Otto GM, Williams RL, Wang J, Lee C, Tschida BR, Das P, Dubuc AM, Moriarity BS, ... ... Largaespada DA, et al. Sleeping Beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors. Cancer Research. PMID 30674530 DOI: 10.1158/0008-5472.CAN-18-1261  0.92
2018 Li XX, Lu XY, Zhang SJ, Chiu AP, Lo LH, Largaespada DA, Chen QB, Keng VW. Sodium tanshinone IIA sulfonate ameliorates hepatic steatosis by inhibiting lipogenesis and inflammation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 111: 68-75. PMID 30576936 DOI: 10.1016/j.biopha.2018.12.019  0.44
2018 Rahrmann EP, Wolf NK, Otto GM, Heltemes Harris L, Ramsey LB, Shu J, LaRue RS, Linden MA, Rathe SK, Starr TK, Farrar MA, Moriarity BS, Largaespada DA. Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma. Molecular Cancer Research : McR. PMID 30355676 DOI: 10.1158/1541-7786.MCR-18-0582  0.84
2018 Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, ... ... Largaespada DA, et al. Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. Communications Biology. 1: 158. PMID 30302402 DOI: 10.1038/s42003-018-0163-y  0.52
2018 Razzoli M, Nyuyki-Dufe K, Gurney A, Erickson C, McCallum J, Spielman N, Marzullo M, Patricelli J, Kurata M, Pope EA, Touma C, Palme R, Largaespada DA, Allison DB, Bartolomucci A. Social stress shortens lifespan in mice. Aging Cell. e12778. PMID 29806171 DOI: 10.1111/acel.12778  0.6
2017 Paul JA, Aich A, Abrahante JE, Wang Y, LaRue RS, Rathe SK, Kalland K, Mittal A, Jha R, Peng F, Largaespada DA, Bagchi A, Gupta K. Transcriptomic analysis of gene signatures associated with sickle pain. Scientific Data. 4: 170051. PMID 29292796 DOI: 10.1038/sdata.2017.51  0.84
2017 Carlson M, Watson AL, Anderson L, Largaespada DA, Provenzano PP. Multiphoton fluorescence lifetime imaging of chemotherapy distribution in solid tumors. Journal of Biomedical Optics. 22: 1-9. PMID 29188660 DOI: 10.1117/1.JBO.22.11.116010  0.4
2017 Kurata M, Yamamoto K, Moriarity BS, Kitagawa M, Largaespada DA. CRISPR/Cas9 library screening for drug target discovery. Journal of Human Genetics. PMID 29158600 DOI: 10.1038/s10038-017-0376-9  0.76
2017 Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL. Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma. Cancer Research. PMID 29066513 DOI: 10.1158/0008-5472.CAN-17-0576  0.84
2017 Tschida BR, Temiz NA, Kuka TP, Lee LA, Riordan JD, Tierrablanca CA, Hullsiek R, Wagner S, Hudson WA, Linden MA, Amin K, Beckmann PJ, Heuer RA, Sarver AL, Yang JD, ... ... Largaespada D, et al. Sleeping Beauty insertional mutagenesis in mice identifies drivers of steatosis-associated hepatic tumor. Cancer Research. PMID 28993411 DOI: 10.1158/0008-5472.CAN-17-2281  0.44
2017 Riordan JD, Feddersen CR, Tschida BR, Jackson P, Keng VW, Linden MA, Amin K, Stipp CS, Largaespada DA, Dupuy AJ. Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma. Hepatology (Baltimore, Md.). PMID 28961327 DOI: 10.1002/hep.29565  0.44
2016 Marko TA, Shamsan GA, Edwards EN, Hazelton PE, Rathe SK, Cornax I, Overn PR, Varshney J, Diessner BJ, Moriarity BS, O'Sullivan MG, Odde DJ, Largaespada DA. Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma. Scientific Reports. 6: 39059. PMID 27966608 DOI: 10.1038/srep39059  0.84
2016 Kurata M, Rathe SK, Bailey NJ, Aumann NK, Jones JM, Veldhuijzen GW, Moriarity BS, Largaespada DA. Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML. Scientific Reports. 6: 36199. PMID 27808171 DOI: 10.1038/srep36199  0.84
2016 Eckfeldt CE, Pomeroy EJ, Lee RD, Hazen KS, Lee LA, Moriarity BS, Largaespada DA. RALB provides critical survival signals downstream of Ras in acute myeloid leukemia. Oncotarget. PMID 27556501 DOI: 10.18632/oncotarget.11431  0.76
2016 Kendall JJ, Chaney KE, Patel AV, Rizvi TA, Largaespada DA, Ratner N. CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin. Oncotarget. PMID 27448963 DOI: 10.18632/oncotarget.10668  0.32
2016 Sachs Z, Been RA, DeCoursin KJ, Nguyen HT, Mohd Hassan NA, Noble-Orcutt KE, Eckfeldt CE, Pomeroy EJ, Diaz-Flores E, Geurts JL, Diers MD, Hasz DE, Morgan KJ, MacMillan ML, Shannon KM, ... Largaespada DA, et al. Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency. Haematologica. PMID 27418650 DOI: 10.3324/haematol.2015.136002  0.48
2016 Patel AV, Chaney KE, Choi K, Largaespada DA, Kumar AR, Ratner N. An shRNA screen identifies MEIS1 as a driver of malignant peripheral nerve sheath tumors. Ebiomedicine. PMID 27333032 DOI: 10.1016/j.ebiom.2016.06.007  0.52
2016 Watson AL, Carlson DF, Largaespada DA, Hackett PB, Fahrenkrug SC. Engineered Swine Models of Cancer. Frontiers in Genetics. 7: 78. PMID 27242889 DOI: 10.3389/fgene.2016.00078  0.92
2016 Ho YY, Starr TK, LaRue RS, Largaespada DA. Case-oriented pathways analysis in pancreatic adenocarcinoma using data from a sleeping beauty transposon mutagenesis screen. Bmc Medical Genomics. 9: 16. PMID 27038937 DOI: 10.1186/s12920-016-0176-7  0.92
2016 Stoddart A, Qian Z, Fernald AA, Bergerson RJ, Wang J, Karrison T, Anastasi J, Bartom ET, Sarver AL, McNerney ME, Largaespada DA, Le Beau MM. Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms. Haematologica. PMID 26944478 DOI: 10.3324/haematol.2015.139527  0.48
2016 Wu J, Keng V, Patmore DM, Kendall JJ, Patel AV, Jousma E, Jessen WJ, Choi K, Tschida BR, Silverstein KA, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim MO, ... ... Largaespada DA, et al. Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation. Cell Reports. PMID 26904939 DOI: 10.1016/j.celrep.2016.01.074  0.92
2016 Shu J, Li L, Sarver AE, Pope EA, Varshney J, Thayanithy V, Spector L, Largaespada DA, Steer CJ, Subramanian S. Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma. Oncotarget. PMID 26802029 DOI: 10.18632/oncotarget.6965  0.92
2015 Wolf NK, Largaespada DA, Moriarity BS. Coping with cancer genes altered by copy number. Oncotarget. 6: 35155-6. PMID 26577648 DOI: 10.18632/oncotarget.6215  0.92
2015 Chiu AP, Tschida BR, Lo LH, Moriarity BS, Rowlands DK, Largaespada DA, Keng VW. Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma. World Journal of Gastroenterology. 21: 12157-70. PMID 26576100 DOI: 10.3748/wjg.v21.i42.12157  0.92
2015 Temiz NA, Moriarity BS, Wolf NK, Riordan JD, Dupuy AJ, Largaespada DA, Sarver AL. RNA sequencing of Sleeping Beauty transposon-induced tumors detect transposon-RNA fusions allowing precision analyses of forward genetic cancer screens. Genome Research. PMID 26553456 DOI: 10.1101/gr.188649.114  0.92
2015 Heltemes-Harris LM, Larson JD, Starr TK, Hubbard GK, Sarver AL, Largaespada DA, Farrar MA. Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemia. Oncogene. PMID 26500062 DOI: 10.1038/onc.2015.405  0.92
2015 Kempema AM, Widen JC, Hexum JK, Andrews TE, Wang D, Rathe SK, Meece FA, Noble KE, Sachs Z, Largaespada DA, Harki DA. Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues. Bioorganic & Medicinal Chemistry. 23: 4737-45. PMID 26088334 DOI: 10.1016/j.bmc.2015.05.037  0.92
2015 Moriarity BS, Largaespada DA. Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery. Current Opinion in Genetics & Development. 30: 66-72. PMID 26051241 DOI: 10.1016/j.gde.2015.04.007  0.92
2015 Dorr C, Janik C, Weg M, Been RA, Bader J, Kang R, Ng B, Foran L, Landman SR, O'Sullivan MG, Steinbach M, Sarver AL, Silverstein KA, Largaespada DA, Starr TK. Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor. Molecular Cancer Research : McR. 13: 1238-47. PMID 25995385 DOI: 10.1158/1541-7786.MCR-14-0674-T  0.92
2015 Hexum JK, Becker CM, Kempema AM, Ohlfest JR, Largaespada DA, Harki DA. Parthenolide prodrug LC-1 slows growth of intracranial glioma. Bioorganic & Medicinal Chemistry Letters. 25: 2493-5. PMID 25978958 DOI: 10.1016/j.bmcl.2015.04.058  0.92
2015 Becker CM, Oberoi RK, McFarren SJ, Muldoon DM, Pafundi DH, Pokorny JL, Brinkmann DH, Ohlfest JR, Sarkaria JN, Largaespada DA, Elmquist WF. Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma. Neuro-Oncology. PMID 25972455 DOI: 10.1093/neuonc/nov081  0.92
2015 Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, ... ... Largaespada DA, et al. A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. Nature Genetics. 47: 615-24. PMID 25961939 DOI: 10.1038/ng.3293  0.92
2014 Sachs Z, LaRue RS, Nguyen HT, Sachs K, Noble KE, Mohd Hassan NA, Diaz-Flores E, Rathe SK, Sarver AL, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon KM, Largaespada DA. NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia. Blood. 124: 3274-83. PMID 25316678 DOI: 10.1182/blood-2013-08-521708  0.92
2014 Rathe SK, Moriarity BS, Stoltenberg CB, Kurata M, Aumann NK, Rahrmann EP, Bailey NJ, Melrose EG, Beckmann DA, Liska CR, Largaespada DA. Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia. Scientific Reports. 4: 6048. PMID 25116387 DOI: 10.1038/srep06048  0.92
2014 Tseng YY, Moriarity BS, Gong W, Akiyama R, Tiwari A, Kawakami H, Ronning P, Reuland B, Guenther K, Beadnell TC, Essig J, Otto GM, O'Sullivan MG, Largaespada DA, Schwertfeger KL, et al. PVT1 dependence in cancer with MYC copy-number increase. Nature. 512: 82-6. PMID 25043044 DOI: 10.1038/nature13311  0.92
2014 Li MV, Shukla D, Rhodes BH, Lall A, Shu J, Moriarity BS, Largaespada DA. HomeRun Vector Assembly System: a flexible and standardized cloning system for assembly of multi-modular DNA constructs. Plos One. 9: e100948. PMID 24959875 DOI: 10.1371/journal.pone.0100948  0.92
2014 Litterman AJ, Zellmer DM, LaRue RS, Jameson SC, Largaespada DA. Antigen-specific culture of memory-like CD8 T cells for adoptive immunotherapy. Cancer Immunology Research. 2: 839-45. PMID 24852944 DOI: 10.1158/2326-6066.CIR-14-0038  0.92
2014 Rahrmann EP, Moriarity BS, Otto GM, Watson AL, Choi K, Collins MH, Wallace M, Webber BR, Forster CL, Rizzardi AE, Schmechel SC, Ratner N, Largaespada DA. Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis. The American Journal of Pathology. 184: 2082-98. PMID 24832557 DOI: 10.1016/j.ajpath.2014.04.006  0.92
2014 Been RA, Linden MA, Hager CJ, DeCoursin KJ, Abrahante JE, Landman SR, Steinbach M, Sarver AL, Largaespada DA, Starr TK. Genetic signature of histiocytic sarcoma revealed by a sleeping beauty transposon genetic screen in mice. Plos One. 9: e97280. PMID 24827933 DOI: 10.1371/journal.pone.0097280  0.92
2014 Moriarity BS, Rahrmann EP, Beckmann DA, Conboy CB, Watson AL, Carlson DF, Olson ER, Hyland KA, Fahrenkrug SC, McIvor RS, Largaespada DA. Simple and efficient methods for enrichment and isolation of endonuclease modified cells. Plos One. 9: e96114. PMID 24798371 DOI: 10.1371/journal.pone.0096114  0.92
2014 Watson AL, Anderson LK, Greeley AD, Keng VW, Rahrmann EP, Halfond AL, Powell NM, Collins MH, Rizvi T, Moertel CL, Ratner N, Largaespada DA. Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity. Oncotarget. 5: 1502-14. PMID 24681606  0.92
2014 Tschida BR, Largaespada DA, Keng VW. Mouse models of cancer: Sleeping Beauty transposons for insertional mutagenesis screens and reverse genetic studies. Seminars in Cell & Developmental Biology. 27: 86-95. PMID 24468652 DOI: 10.1016/j.semcdb.2014.01.006  0.44
2013 Litterman AJ, Dudek AZ, Largaespada DA. Alkylating chemotherapy may exert a uniquely deleterious effect upon neo-antigen-targeting anticancer vaccination. Oncoimmunology. 2: e26294. PMID 24251080 DOI: 10.4161/onci.26294  0.92
2013 Been RA, Ross JA, Nagel CW, Hooten AJ, Langer EK, DeCoursin KJ, Marek CA, Janik CL, Linden MA, Reed RC, Schutten MM, Largaespada DA, Johnson KJ. Perigestational dietary folic acid deficiency protects against medulloblastoma formation in a mouse model of nevoid basal cell carcinoma syndrome. Nutrition and Cancer. 65: 857-65. PMID 23909730 DOI: 10.1080/01635581.2013.804940  0.92
2013 Rathe SK, Johnson JE, Silverstein KA, Erdmann JJ, Watson AL, Popescu FE, Ohlfest JR, Largaespada DA. MMuFLR: missense mutation and frameshift location reporter. Bioinformatics (Oxford, England). 29: 2353-4. PMID 23825368 DOI: 10.1093/bioinformatics/btt385  0.92
2013 Rahrmann EP, Watson AL, Keng VW, Choi K, Moriarity BS, Beckmann DA, Wolf NK, Sarver A, Collins MH, Moertel CL, Wallace MR, Gel B, Serra E, Ratner N, Largaespada DA. Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis. Nature Genetics. 45: 756-66. PMID 23685747 DOI: 10.1038/ng.2641  0.92
2013 Rahrmann EP, Largaespada DA. Retrotransposons: a new and credible source of inherited and somatically acquired hepatocellular carcinoma mutations. Journal of Hepatology. 59: 616-7. PMID 23665280 DOI: 10.1016/j.jhep.2013.05.001  0.92
2013 Riordan JD, Keng VW, Tschida BR, Scheetz TE, Bell JB, Podetz-Pedersen KM, Moser CD, Copeland NG, Jenkins NA, Roberts LR, Largaespada DA, Dupuy AJ. Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis. Plos Genetics. 9: e1003441. PMID 23593033 DOI: 10.1371/journal.pgen.1003441  0.92
2013 Watson AL, Rahrmann EP, Moriarity BS, Choi K, Conboy CB, Greeley AD, Halfond AL, Anderson LK, Wahl BR, Keng VW, Rizzardi AE, Forster CL, Collins MH, Sarver AL, Wallace MR, ... ... Largaespada DA, et al. Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance. Cancer Discovery. 3: 674-89. PMID 23535903 DOI: 10.1158/2159-8290.CD-13-0081  0.92
2013 Moriarity BS, Rahrmann EP, Keng VW, Manlove LS, Beckmann DA, Wolf NK, Khurshid T, Bell JB, Largaespada DA. Modular assembly of transposon integratable multigene vectors using RecWay assembly. Nucleic Acids Research. 41: e92. PMID 23444141 DOI: 10.1093/nar/gkt115  0.92
2013 Hackett PB, Largaespada DA, Switzer KC, Cooper LJ. Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy. Translational Research : the Journal of Laboratory and Clinical Medicine. 161: 265-83. PMID 23313630 DOI: 10.1016/j.trsl.2012.12.005  0.92
2013 Omidvar N, Maunakea ML, Jones L, Sevcikova S, Yin B, Himmel KL, Tennant TR, Le Beau MM, Largaespada DA, Kogan SC. PML-RARα co-operates with Sox4 in acute myeloid leukemia development in mice. Haematologica. 98: 424-7. PMID 23144197 DOI: 10.3324/haematol.2011.057067  0.92
2013 Keng VW, Sia D, Sarver AL, Tschida BR, Fan D, Alsinet C, Solé M, Lee WL, Kuka TP, Moriarity BS, Villanueva A, Dupuy AJ, Riordan JD, Bell JB, Silverstein KA, ... ... Largaespada DA, et al. Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR. Hepatology (Baltimore, Md.). 57: 120-30. PMID 22899566 DOI: 10.1002/hep.26004  0.92
2012 Keng VW, Watson AL, Rahrmann EP, Li H, Tschida BR, Moriarity BS, Choi K, Rizvi TA, Collins MH, Wallace MR, Ratner N, Largaespada DA. Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST. Sarcoma. 2012: 620834. PMID 23319880 DOI: 10.1155/2012/620834  0.92
2012 Solyom S, Ewing AD, Rahrmann EP, Doucet T, Nelson HH, Burns MB, Harris RS, Sigmon DF, Casella A, Erlanger B, Wheelan S, Upton KR, Shukla R, Faulkner GJ, Largaespada DA, et al. Extensive somatic L1 retrotransposition in colorectal tumors. Genome Research. 22: 2328-38. PMID 22968929 DOI: 10.1101/gr.145235.112  0.92
2012 Seshagiri S, Stawiski EW, Durinck S, Modrusan Z, Storm EE, Conboy CB, Chaudhuri S, Guan Y, Janakiraman V, Jaiswal BS, Guillory J, Ha C, Dijkgraaf GJ, Stinson J, Gnad F, ... ... Largaespada DA, et al. Recurrent R-spondin fusions in colon cancer. Nature. 488: 660-4. PMID 22895193 DOI: 10.1038/nature11282  0.92
2012 Larson JD, Largaespada DA. Review: In vivo models for defining molecular subtypes of the primitive neuroectodermal tumor genome: current challenges and solutions. In Vivo (Athens, Greece). 26: 487-500. PMID 22773561  0.92
2012 Sarver AL, Erdman J, Starr T, Largaespada DA, Silverstein KA. TAPDANCE: an automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data. Bmc Bioinformatics. 13: 154. PMID 22748055 DOI: 10.1186/1471-2105-13-154  0.92
2012 Keng VW, Rahrmann EP, Watson AL, Tschida BR, Moertel CL, Jessen WJ, Rizvi TA, Collins MH, Ratner N, Largaespada DA. PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors. Cancer Research. 72: 3405-13. PMID 22700876 DOI: 10.1158/0008-5472.CAN-11-4092  0.92
2012 Pérez-Mancera PA, Rust AG, van der Weyden L, Kristiansen G, Li A, Sarver AL, Silverstein KA, Grützmann R, Aust D, Rümmele P, Knösel T, Herd C, Stemple DL, Kettleborough R, Brosnan JA, ... ... Largaespada DA, et al. The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature. 486: 266-70. PMID 22699621 DOI: 10.1038/nature11114  0.92
2012 O'Donnell KA, Keng VW, York B, Reineke EL, Seo D, Fan D, Silverstein KA, Schrum CT, Xie WR, Mularoni L, Wheelan SJ, Torbenson MS, O'Malley BW, Largaespada DA, Boeke JD. A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: E1377-86. PMID 22556267 DOI: 10.1073/pnas.1115433109  0.92
2012 Bergerson RJ, Collier LS, Sarver AL, Been RA, Lugthart S, Diers MD, Zuber J, Rappaport AR, Nixon MJ, Silverstein KA, Fan D, Lamblin AF, Wolff L, Kersey JH, Delwel R, ... ... Largaespada DA, et al. An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model. Blood. 119: 4512-23. PMID 22427200 DOI: 10.1182/blood-2010-04-281428  0.92
2012 Keng VW, Largaespada DA, Villanueva A. Why men are at higher risk for hepatocellular carcinoma? Journal of Hepatology. 57: 453-4. PMID 22425699 DOI: 10.1016/j.jhep.2012.03.004  0.44
2012 Wu X, Northcott PA, Dubuc A, Dupuy AJ, Shih DJ, Witt H, Croul S, Bouffet E, Fults DW, Eberhart CG, Garzia L, Van Meter T, Zagzag D, Jabado N, Schwartzentruber J, ... ... Largaespada DA, et al. Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature. 482: 529-33. PMID 22343890 DOI: 10.1038/nature10825  0.92
2012 Bergemann TL, Starr TK, Yu H, Steinbach M, Erdmann J, Chen Y, Cormier RT, Largaespada DA, Silverstein KA. New methods for finding common insertion sites and co-occurring common insertion sites in transposon- and virus-based genetic screens. Nucleic Acids Research. 40: 3822-33. PMID 22241771 DOI: 10.1093/nar/gkr1295  0.92
2011 Wilber A, Ulloa Montoya F, Hammer L, Moriarity BS, Geurts AM, Largaespada DA, Verfaillie CM, McIvor RS, Lakshmipathy U. Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells. Stem Cells International. 2011: 717069. PMID 21977042 DOI: 10.4061/2011/717069  0.92
2011 Wiesner SM, Geurts JL, Diers MD, Bergerson RJ, Hasz DE, Morgan KJ, Largaespada DA. Nf1 mutant mice with p19ARF gene loss develop accelerated hematopoietic disease resembling acute leukemia with a variable phenotype. American Journal of Hematology. 86: 579-85. PMID 21681782 DOI: 10.1002/ajh.22035  0.92
2011 McGrail M, Hatler JM, Kuang X, Liao HK, Nannapaneni K, Watt KE, Uhl JD, Largaespada DA, Vollbrecht E, Scheetz TE, Dupuy AJ, Hostetter JM, Essner JJ. Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish. Plos One. 6: e18826. PMID 21533036 DOI: 10.1371/journal.pone.0018826  0.92
2011 Starr TK, Scott PM, Marsh BM, Zhao L, Than BL, O'Sullivan MG, Sarver AL, Dupuy AJ, Largaespada DA, Cormier RT. A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 5765-70. PMID 21436051 DOI: 10.1073/pnas.1018012108  0.92
2011 Keng VW, Tschida BR, Bell JB, Largaespada DA. Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system. Hepatology (Baltimore, Md.). 53: 781-90. PMID 21374658 DOI: 10.1002/hep.24091  0.44
2011 Varela I, Tarpey P, Raine K, Huang D, Ong CK, Stephens P, Davies H, Jones D, Lin ML, Teague J, Bignell G, Butler A, Cho J, Dalgliesh GL, Galappaththige D, ... ... Largaespada DA, et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature. 469: 539-42. PMID 21248752 DOI: 10.1038/nature09639  0.92
2011 Carlson DF, Geurts AM, Garbe JR, Park CW, Rangel-Filho A, O'Grady SM, Jacob HJ, Steer CJ, Largaespada DA, Fahrenkrug SC. Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. Transgenic Research. 20: 29-45. PMID 20352328 DOI: 10.1007/s11248-010-9386-5  0.92
2010 Rathe SK, Largaespada DA. Deoxycytidine kinase is downregulated in Ara-C-resistant acute myeloid leukemia murine cell lines. Leukemia. 24: 1513-5. PMID 20508618 DOI: 10.1038/leu.2010.88  0.92
2010 Bender AM, Collier LS, Rodriguez FJ, Tieu C, Larson JD, Halder C, Mahlum E, Kollmeyer TM, Akagi K, Sarkar G, Largaespada DA, Jenkins RB. Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomas. Cancer Research. 70: 3557-65. PMID 20388773 DOI: 10.1158/0008-5472.CAN-09-4674  0.92
2010 Mattison J, Kool J, Uren AG, de Ridder J, Wessels L, Jonkers J, Bignell GR, Butler A, Rust AG, Brosch M, Wilson CH, van der Weyden L, Largaespada DA, Stratton MR, Futreal PA, et al. Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach. Cancer Research. 70: 883-95. PMID 20103622 DOI: 10.1158/0008-5472.CAN-09-1737  0.92
2009 Collier LS, Adams DJ, Hackett CS, Bendzick LE, Akagi K, Davies MN, Diers MD, Rodriguez FJ, Bender AM, Tieu C, Matise I, Dupuy AJ, Copeland NG, Jenkins NA, Hodgson JG, ... ... Largaespada DA, et al. Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality. Cancer Research. 69: 8429-37. PMID 19843846 DOI: 10.1158/0008-5472.CAN-09-1760  0.92
2009 Dupuy AJ, Rogers LM, Kim J, Nannapaneni K, Starr TK, Liu P, Largaespada DA, Scheetz TE, Jenkins NA, Copeland NG. A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice. Cancer Research. 69: 8150-6. PMID 19808965 DOI: 10.1158/0008-5472.CAN-09-1135  0.92
2009 Keng VW, Ryan BJ, Wangensteen KJ, Balciunas D, Schmedt C, Ekker SC, Largaespada DA. Efficient transposition of Tol2 in the mouse germline. Genetics. 183: 1565-73. PMID 19805821 DOI: 10.1534/genetics.109.100768  0.92
2009 Johnson KJ, Springer NM, Bielinsky AK, Largaespada DA, Ross JA. Developmental origins of cancer. Cancer Research. 69: 6375-7. PMID 19654290 DOI: 10.1158/0008-5472.CAN-09-1391  0.92
2009 Rahrmann EP, Collier LS, Knutson TP, Doyal ME, Kuslak SL, Green LE, Malinowski RL, Roethe L, Akagi K, Waknitz M, Huang W, Largaespada DA, Marker PC. Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screen. Cancer Research. 69: 4388-97. PMID 19401450 DOI: 10.1158/0008-5472.CAN-08-3901  0.92
2009 Starr TK, Allaei R, Silverstein KA, Staggs RA, Sarver AL, Bergemann TL, Gupta M, O'Sullivan MG, Matise I, Dupuy AJ, Collier LS, Powers S, Oberg AL, Asmann YW, Thibodeau SN, ... ... Largaespada DA, et al. A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. Science (New York, N.Y.). 323: 1747-50. PMID 19251594 DOI: 10.1126/science.1163040  0.92
2009 Keng VW, Villanueva A, Chiang DY, Dupuy AJ, Ryan BJ, Matise I, Silverstein KA, Sarver A, Starr TK, Akagi K, Tessarollo L, Collier LS, Powers S, Lowe SW, Jenkins NA, ... ... Largaespada DA, et al. A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nature Biotechnology. 27: 264-74. PMID 19234449 DOI: 10.1038/nbt.1526  0.92
2009 Wiesner SM, Decker SA, Larson JD, Ericson K, Forster C, Gallardo JL, Long C, Demorest ZL, Zamora EA, Low WC, SantaCruz K, Largaespada DA, Ohlfest JR. De novo induction of genetically engineered brain tumors in mice using plasmid DNA. Cancer Research. 69: 431-9. PMID 19147555 DOI: 10.1158/0008-5472.CAN-08-1800  0.92
2009 Kim WI, Matise I, Diers MD, Largaespada DA. RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia. Blood. 113: 1086-96. PMID 18952898 DOI: 10.1182/blood-2008-01-132316  0.92
2009 Yin B, Delwel R, Valk PJ, Wallace MR, Loh ML, Shannon KM, Largaespada DA. A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene. Blood. 113: 1075-85. PMID 18948576 DOI: 10.1182/blood-2008-03-144436  0.36
2008 Wangensteen KJ, Wilber A, Keng VW, He Z, Matise I, Wangensteen L, Carson CM, Chen Y, Steer CJ, McIvor RS, Largaespada DA, Wang X, Ekker SC. A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver. Hepatology (Baltimore, Md.). 47: 1714-24. PMID 18435462 DOI: 10.1002/hep.22195  0.92
2008 Largaespada DA, Collier LS. Transposon-mediated mutagenesis in somatic cells: identification of transposon-genomic DNA junctions. Methods in Molecular Biology (Clifton, N.J.). 435: 95-108. PMID 18370070 DOI: 10.1007/978-1-59745-232-8_7  0.92
2007 Collier LS, Largaespada DA. Transposable elements and the dynamic somatic genome. Genome Biology. 8: S5. PMID 18047697 DOI: 10.1186/gb-2007-8-s1-s5  0.92
2007 Collier LS, Largaespada DA. Transposons for cancer gene discovery: Sleeping Beauty and beyond. Genome Biology. 8: S15. PMID 18047692 DOI: 10.1186/gb-2007-8-s1-s15  0.92
2007 Yin B, Largaespada DA. PCR-based procedures to isolate insertion sites of DNA elements. Biotechniques. 43: 79-84. PMID 17695256 DOI: 10.2144/000112474  0.92
2007 Kim WI, Wiesner SM, Largaespada DA. Vav promoter-tTA conditional transgene expression system for hematopoietic cells drives high level expression in developing B and T cells. Experimental Hematology. 35: 1231-9. PMID 17560009 DOI: 10.1016/j.exphem.2007.04.012  0.92
2007 Yin B, Tsai ML, Hasz DE, Rathe SK, Le Beau MM, Largaespada DA. A microarray study of altered gene expression after cytarabine resistance in acute myeloid leukemia. Leukemia. 21: 1093-7. PMID 17301810 DOI: 10.1038/sj.leu.2404595  0.92
2007 Thielen JL, Volzing KG, Collier LS, Green LE, Largaespada DA, Marker PC. Markers of prostate region-specific epithelial identity define anatomical locations in the mouse prostate that are molecularly similar to human prostate cancers. Differentiation; Research in Biological Diversity. 75: 49-61. PMID 17244021 DOI: 10.1111/j.1432-0436.2006.00115.x  0.92
2007 Morgan KJ, Rowley MA, Wiesner SM, Hasz DE, Van Ness B, Largaespada DA. The GAP-related domain of neurofibromin attenuates proliferation and downregulates N- and K-Ras activation in Nf1-negative AML cells. Leukemia Research. 31: 1107-13. PMID 17222906 DOI: 10.1016/j.leukres.2006.11.022  0.92
2007 Kim A, Morgan K, Hasz DE, Wiesner SM, Lauchle JO, Geurts JL, Diers MD, Le DT, Kogan SC, Parada LF, Shannon K, Largaespada DA. Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice. Blood. 109: 1687-91. PMID 17090653 DOI: 10.1182/blood-2006-05-025395  0.92
2006 Score PR, Belur LR, Frandsen JL, Geurts JL, Yamaguchi T, Somia NV, Hackett PB, Largaespada DA, McIvor RS. Erratum to "Sleeping Beauty-Mediated Transposition and Long-Term Expression in Vivo: Use of the LoxP/Cre Recombinase System to Distinguish Transposition-Specific Expression". Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 149. PMID 28192690 DOI: 10.1016/j.ymthe.2006.03.011  0.48
2006 Balciunas D, Wangensteen KJ, Wilber A, Bell J, Geurts A, Sivasubbu S, Wang X, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. Plos Genetics. 2: e169. PMID 17096595 DOI: 10.1371/journal.pgen.0020169  0.92
2006 Geurts AM, Collier LS, Geurts JL, Oseth LL, Bell ML, Mu D, Lucito R, Godbout SA, Green LE, Lowe SW, Hirsch BA, Leinwand LA, Largaespada DA. Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. Plos Genetics. 2: e156. PMID 17009875 DOI: 10.1371/journal.pgen.0020156  0.92
2006 Geurts AM, Wilber A, Carlson CM, Lobitz PD, Clark KJ, Hackett PB, McIvor RS, Largaespada DA. Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon. Bmc Biotechnology. 6: 30. PMID 16800892 DOI: 10.1186/1472-6750-6-30  0.92
2006 Geurts AM, Hackett CS, Bell JB, Bergemann TL, Collier LS, Carlson CM, Largaespada DA, Hackett PB. Structure-based prediction of insertion-site preferences of transposons into chromosomes. Nucleic Acids Research. 34: 2803-11. PMID 16717285 DOI: 10.1093/nar/gkl301  0.92
2006 Yin B, Kogan SC, Dickins RA, Lowe SW, Largaespada DA. Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia. Experimental Hematology. 34: 631-41. PMID 16647569 DOI: 10.1016/j.exphem.2006.01.015  0.36
2006 Wilber A, Frandsen JL, Geurts JL, Largaespada DA, Hackett PB, McIvor RS. RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 625-30. PMID 16368272 DOI: 10.1016/j.ymthe.2005.10.014  0.92
2006 Score PR, Belur LR, Frandsen JL, Geurts JL, Guerts JL, Yamaguchi T, Somia NV, Hackett PB, Largaespada DA, McIvor RS. Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 617-24. PMID 16356773 DOI: 10.1016/j.ymthe.2005.10.015  0.92
2006 Collier LS, Largaespada DA. Transforming science: cancer gene identification. Current Opinion in Genetics & Development. 16: 23-9. PMID 16326095 DOI: 10.1016/j.gde.2005.11.001  0.92
2005 Ohlfest JR, Freese AB, Largaespada DA. Nonviral vectors for cancer gene therapy: prospects for integrating vectors and combination therapies. Current Gene Therapy. 5: 629-41. PMID 16457652 DOI: 10.2174/156652305774964749  0.92
2005 Carlson CM, Frandsen JL, Kirchhof N, McIvor RS, Largaespada DA. Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 102: 17059-64. PMID 16286660 DOI: 10.1073/pnas.0502974102  0.92
2005 Collier LS, Largaespada DA. Hopping around the tumor genome: transposons for cancer gene discovery. Cancer Research. 65: 9607-10. PMID 16266976 DOI: 10.1158/0008-5472.CAN-05-3085  0.92
2005 Ohlfest JR, Demorest ZL, Motooka Y, Vengco I, Oh S, Chen E, Scappaticci FA, Saplis RJ, Ekker SC, Low WC, Freese AB, Largaespada DA. Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 778-88. PMID 16150649 DOI: 10.1016/j.ymthe.2005.07.689  0.92
2005 Hackett PB, Ekker SC, Largaespada DA, McIvor RS. Sleeping beauty transposon-mediated gene therapy for prolonged expression. Advances in Genetics. 54: 189-232. PMID 16096013 DOI: 10.1016/S0065-2660(05)54009-4  0.92
2005 Collier LS, Carlson CM, Ravimohan S, Dupuy AJ, Largaespada DA. Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse. Nature. 436: 272-6. PMID 16015333 DOI: 10.1038/nature03681  0.92
2005 Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA. Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature. 436: 221-6. PMID 16015321 DOI: 10.1038/nature03691  0.92
2005 Carlson CM, Largaespada DA. Insertional mutagenesis in mice: new perspectives and tools. Nature Reviews. Genetics. 6: 568-80. PMID 15995698 DOI: 10.1038/nrg1638  0.92
2005 Wiesner SM, Jones JM, Hasz DE, Largaespada DA. Repressible transgenic model of NRAS oncogene-driven mast cell disease in the mouse. Blood. 106: 1054-62. PMID 15831708 DOI: 10.1182/blood-2004-08-3306  0.92
2005 Liu G, Geurts AM, Yae K, Srinivasan AR, Fahrenkrug SC, Largaespada DA, Takeda J, Horie K, Olson WK, Hackett PB. Target-site preferences of Sleeping Beauty transposons. Journal of Molecular Biology. 346: 161-73. PMID 15663935 DOI: 10.1016/j.jmb.2004.09.086  0.92
2005 Ohlfest JR, Frandsen JL, Fritz S, Lobitz PD, Perkinson SG, Clark KJ, Nelsestuen G, Key NS, McIvor RS, Hackett PB, Largaespada DA. Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system. Blood. 105: 2691-8. PMID 15576475 DOI: 10.1182/blood-2004-09-3496  0.92
2004 Ohlfest JR, Lobitz PD, Perkinson SG, Largaespada DA. Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 260-8. PMID 15294173 DOI: 10.1016/j.ymthe.2004.05.005  0.92
2003 Carlson CM, Dupuy AJ, Fritz S, Roberg-Perez KJ, Fletcher CF, Largaespada DA. Transposon mutagenesis of the mouse germline. Genetics. 165: 243-56. PMID 14504232  0.92
2003 Belur LR, Frandsen JL, Dupuy AJ, Ingbar DH, Largaespada DA, Hackett PB, Scott McIvor R. Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 501-7. PMID 12946324 DOI: 10.1016/S1525-0016(03)00211-9  0.92
2003 Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB. Gene transfer into genomes of human cells by the sleeping beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 108-17. PMID 12842434 DOI: 10.1016/S1525-0016(03)00099-6  0.92
2003 Keene CD, Ortiz-Gonzalez XR, Jiang Y, Largaespada DA, Verfaillie CM, Low WC. Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos. Cell Transplantation. 12: 201-13. PMID 12797375  0.92
2003 Roberg-Perez K, Carlson CM, Largaespada DA. MTID: a database of Sleeping Beauty transposon insertions in mice. Nucleic Acids Research. 31: 78-81. PMID 12519952 DOI: 10.1093/nar/gkg045  0.92
2002 Rizvi TA, Huang Y, Sidani A, Atit R, Largaespada DA, Boissy RE, Ratner N. A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9831-40. PMID 12427839  0.92
2002 Dupuy AJ, Clark K, Carlson CM, Fritz S, Davidson AE, Markley KM, Finley K, Fletcher CF, Ekker SC, Hackett PB, Horn S, Largaespada DA. Mammalian germ-line transgenesis by transposition. Proceedings of the National Academy of Sciences of the United States of America. 99: 4495-9. PMID 11904379 DOI: 10.1073/pnas.062630599  0.92
2002 Himmel KL, Bi F, Shen H, Jenkins NA, Copeland NG, Zheng Y, Largaespada DA. Activation of Clg, a novel Dbl family guanine nucleotide exchange factor gene, by proviral insertion at Evi24, a common integration site in B cell and myeloid leukemias Journal of Biological Chemistry. 277: 13463-13472. PMID 11839748 DOI: 10.1074/jbc.M110981200  0.92
1999 Li J, Shen H, Himmel KL, Dupuy AJ, Largaespada DA, Nakamura T, Shaughnessy JD, Jenkins NA, Copeland NG. Leukaemia disease genes: large-scale cloning and pathway predictions. Nature Genetics. 23: 348-53. PMID 10610183 DOI: 10.1038/15531  0.92
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