Year |
Citation |
Score |
2024 |
Liu T, Gu L, Mui A, Wu Z, Albadari N, Li W, Zhou M. An MDM2 degrader shows potent cytotoxicity to MDM2-overexpressing acute lymphoblastic leukemia cells with minimal toxicity to normal cells/tissues. Cancer Letters. 598: 217126. PMID 39053726 DOI: 10.1016/j.canlet.2024.217126 |
0.325 |
|
2023 |
Albadari N, Xie Y, Liu T, Wang R, Gu L, Zhou M, Wu Z, Li W. Synthesis and biological evaluation of dual MDM2/XIAP inhibitors based on the tetrahydroquinoline scaffold. European Journal of Medicinal Chemistry. 255: 115423. PMID 37130471 DOI: 10.1016/j.ejmech.2023.115423 |
0.313 |
|
2022 |
Liu T, Gu L, Wu Z, Albadari N, Li W, Zhou M. MYCN mRNA degradation and cancer suppression by a selective small-molecule inhibitor in MYCN-amplified neuroblastoma. Frontiers in Oncology. 12: 1058726. PMID 36505784 DOI: 10.3389/fonc.2022.1058726 |
0.306 |
|
2022 |
Liao Y, Chen CH, Xiao T, de la Peña Avalos B, Dray EV, Cai C, Gao S, Shah N, Zhang Z, Feit A, Xue P, Liu Z, Yang M, Lee JH, Xu H, ... Li W, et al. Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35031563 DOI: 10.1073/pnas.2105898119 |
0.485 |
|
2021 |
Niu S, Li J, Bo W, Yang W, Zuccolo A, Giacomello S, Chen X, Han F, Yang J, Song Y, Nie Y, Zhou B, Wang P, Zuo Q, Zhang H, ... ... Li W, ... ... Li W, et al. The Chinese pine genome and methylome unveil key features of conifer evolution. Cell. PMID 34965378 DOI: 10.1016/j.cell.2021.12.006 |
0.343 |
|
2021 |
Shi B, Li W, Song Y, Wang Z, Ju R, Ulman A, Hu J, Palomba F, Zhao Y, Le JP, Jarrard W, Dimoff D, Digman MA, Gratton E, Zang C, et al. UTX condensation underlies its tumour-suppressive activity. Nature. PMID 34526716 DOI: 10.1038/s41586-021-03903-7 |
0.517 |
|
2020 |
Xu L, Liu X, Peng F, Zhang W, Zheng L, Ding Y, Gu T, Lv K, Wang J, Ortinau L, Hu T, Shi X, Shi G, Shang G, Sun S, ... ... Li W, et al. Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions. Nature Cell Biology. PMID 32958856 DOI: 10.1038/S41556-020-00581-X |
0.3 |
|
2020 |
Mao Y, Guo L, Luo Y, Tang Z, Li W, Dong W. Sexual reproduction potential implied by functional analysis of SPO11 in Phaeodactylum tricornutum. Gene. 144929. PMID 32622990 DOI: 10.1016/J.Gene.2020.144929 |
0.303 |
|
2020 |
Li W, Zhang N, Jin C, Long MD, Rajabi H, Yasumizu Y, Fushimi A, Yamashita N, Hagiwara M, Zheng R, Wang J, Kui L, Singh H, Kharbanda S, Hu Q, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. Jci Insight. PMID 32427590 DOI: 10.1172/Jci.Insight.137112 |
0.322 |
|
2020 |
Shu S, Wu HJ, Ge JY, Zeid R, Harris IS, Jovanović B, Murphy K, Wang B, Qiu X, Endress JE, Reyes J, Lim K, Font-Tello A, Syamala S, Xiao T, ... ... Li W, et al. Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. Molecular Cell. PMID 32416067 DOI: 10.1016/J.Molcel.2020.04.027 |
0.324 |
|
2020 |
Liu X, Olszewski K, Zhang Y, Lim EW, Shi J, Zhang X, Zhang J, Lee H, Koppula P, Lei G, Zhuang L, You MJ, Fang B, Li W, Metallo CM, et al. Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer. Nature Cell Biology. PMID 32231310 DOI: 10.1038/S41556-020-0496-X |
0.321 |
|
2020 |
Zheng ZY, Anurag M, Lei JT, Cao J, Singh P, Peng J, Kennedy H, Nguyen NC, Chen Y, Lavere P, Li J, Du XH, Cakar B, Song W, Kim BJ, ... ... Li W, et al. Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer. Cancer Cell. PMID 32142667 DOI: 10.1016/J.Ccell.2020.02.003 |
0.309 |
|
2020 |
Yasumizu Y, Rajabi H, Jin C, Hata T, Pitroda S, Long MD, Hagiwara M, Li W, Hu Q, Liu S, Yamashita N, Fushimi A, Kui L, Samur M, Yamamoto M, et al. MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer. Nature Communications. 11: 338. PMID 31953400 DOI: 10.1038/S41467-019-14219-6 |
0.315 |
|
2019 |
Fei T, Li W, Peng J, Xiao T, Chen CH, Wu A, Huang J, Zang C, Liu XS, Brown M. Deciphering essential cistromes using genome-wide CRISPR screens. Proceedings of the National Academy of Sciences of the United States of America. PMID 31727847 DOI: 10.1073/Pnas.1908155116 |
0.589 |
|
2019 |
Hata T, Rajabi H, Takahashi H, Yasumizu Y, Li W, Jin C, Long MD, Hu Q, Liu S, Fushimi A, Yamashita N, Kui L, Hong D, Yamamoto M, Miyo M, et al. MUC1-C Activates The NuRD Complex To Drive Dedifferentiation of Triple-Negative Breast Cancer Cells. Cancer Research. PMID 31519689 DOI: 10.1158/0008-5472.Can-19-1034 |
0.312 |
|
2019 |
Rajabi H, Hata T, Li W, Long MD, Hu Q, Liu S, Raina D, Kui L, Yazumizu Y, Hong D, Samur M, Kufe D. MUC1-C represses the RASSF1A tumor suppressor in human carcinoma cells. Oncogene. PMID 31435022 DOI: 10.1038/S41388-019-0940-1 |
0.324 |
|
2019 |
Palaniappan M, Nguyen L, Grimm SL, Xi Y, Xia Z, Li W, Coarfa C. The genomic landscape of estrogen receptor α binding sites in mouse mammary gland. Plos One. 14: e0220311. PMID 31408468 DOI: 10.1371/Journal.Pone.0220311 |
0.346 |
|
2019 |
Hata T, Rajabi H, Yamamoto M, Jin C, Ahmad R, Zhang Y, Kui L, Li W, Yasumitzu Y, Hong D, Miyo M, Hiraki M, Maeda T, Suzuki Y, Takahashi H, et al. TARGETING MUC1-C INHIBITS TWIST1 SIGNALING IN TRIPLE-NEGATIVE BREAST CANCER. Molecular Cancer Therapeutics. PMID 31308076 DOI: 10.1158/1535-7163.Mct-19-0156 |
0.311 |
|
2019 |
Weng T, Ko J, Masamha CP, Xia Z, Xiang Y, Chen NY, Molina JG, Collum S, Mertens TC, Luo F, Philip K, Davies J, Huang J, Wilson C, Thandavarayan RA, ... ... Li W, et al. Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation. The Journal of Clinical Investigation. 130. PMID 30830875 DOI: 10.1172/Jci122106 |
0.308 |
|
2019 |
Cato L, de Tribolet-Hardy J, Lee I, Rottenberg JT, Coleman I, Melchers D, Houtman R, Xiao T, Li W, Uo T, Sun S, Kuznik NC, Göppert B, Ozgun F, van Royen ME, et al. ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer. Cancer Cell. PMID 30773341 DOI: 10.1016/J.Ccell.2019.01.008 |
0.535 |
|
2019 |
Wang B, Wang M, Zhang W, Xiao T, Chen CH, Wu A, Wu F, Traugh N, Wang X, Li Z, Mei S, Cui Y, Shi S, Lipp JJ, Hinterndorfer M, ... Li W, et al. Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute. Nature Protocols. PMID 30710114 DOI: 10.1038/S41596-018-0113-7 |
0.536 |
|
2019 |
Chu Y, Elrod N, Wang C, Li L, Chen T, Routh A, Xia Z, Li W, Wagner EJ, Ji P. Nudt21 regulates the alternative polyadenylation of Pak1 and is predictive in the prognosis of glioblastoma patients. Oncogene. PMID 30705404 DOI: 10.1038/S41388-019-0714-9 |
0.366 |
|
2019 |
Wang WW, Angulo-Ibanez M, Lyu J, Kurra Y, Tong Z, Wu B, Zhang L, Sharma V, Zhou J, Lin H, Gao YQ, Li W, Chua KF, Liu WR. A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7. Journal of the American Chemical Society. PMID 30653310 DOI: 10.1021/Jacs.8B12083 |
0.341 |
|
2018 |
Li L, Li L, Li W, Chen T, Bin Zou, Zhao L, Wang H, Wang X, Xu L, Liu X, Wang D, Li B, Mak TW, Du W, Yang X, et al. TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation. Nature Communications. 9: 4683. PMID 30409970 DOI: 10.1038/S41467-018-07127-8 |
0.306 |
|
2018 |
Mi W, Zhang Y, Lyu J, Wang X, Tong Q, Peng D, Xue Y, Tencer AH, Wen H, Li W, Kutateladze TG, Shi X. The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation. Nature Communications. 9: 3759. PMID 30217978 DOI: 10.1038/S41467-018-06247-5 |
0.309 |
|
2018 |
Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, Sirohi K, Li X, Wei Y, Lee H, Zhuang L, Chen G, Xiao ZD, Hung MC, Chen J, ... Li W, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nature Cell Biology. PMID 30202049 DOI: 10.1038/S41556-018-0178-0 |
0.344 |
|
2018 |
Zhang Y, Xue Y, Shi J, Ahn J, Mi W, Ali M, Wang X, Klein BJ, Wen H, Li W, Shi X, Kutateladze TG. The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3. Nature Structural & Molecular Biology. PMID 30150647 DOI: 10.1038/S41594-018-0114-9 |
0.305 |
|
2018 |
Hu Z, Xia B, Postnikoff SD, Shen ZJ, Tomoiaga AS, Harkness TA, Seol JH, Li W, Chen K, Tyler JK. Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan. Elife. 7. PMID 30117416 DOI: 10.7554/Elife.35551 |
0.325 |
|
2018 |
Chen J, Li HL, Li BB, Li W, Ma D, Li YH, Liu T. Serum- and glucocorticoid-inducible kinase 3 is a potential oncogene in nasopharyngeal carcinoma. Brazilian Journal of Otorhinolaryngology. PMID 30108027 DOI: 10.1016/j.bjorl.2018.05.012 |
0.307 |
|
2018 |
Su J, Huang YH, Cui X, Wang X, Zhang X, Lei Y, Xu J, Lin X, Chen K, Lv J, Goodell MA, Li W. Homeobox oncogene activation by pan-cancer DNA hypermethylation. Genome Biology. 19: 108. PMID 30097071 DOI: 10.1186/S13059-018-1492-3 |
0.317 |
|
2018 |
Feng X, Li L, Wagner EJ, Li W. TC3A: The Cancer 3' UTR Atlas. Nucleic Acids Research. 46: D1027-D1030. PMID 30053266 DOI: 10.1093/Nar/Gkx892 |
0.342 |
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2018 |
Gu T, Lin X, Cullen SM, Luo M, Jeong M, Estecio M, Shen J, Hardikar S, Sun D, Su J, Rux D, Guzman A, Lee M, Qi LS, Chen JJ, ... ... Li W, et al. DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells. Genome Biology. 19: 88. PMID 30001199 DOI: 10.1186/S13059-018-1464-7 |
0.331 |
|
2018 |
Zhang Y, Yang L, Kucherlapati M, Chen F, Hadjipanayis A, Pantazi A, Bristow CA, Lee EA, Mahadeshwar HS, Tang J, Zhang J, Seth S, Lee S, Ren X, Song X, ... ... Li W, et al. A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases. Cell Reports. 24: 515-527. PMID 29996110 DOI: 10.1016/J.Celrep.2018.06.025 |
0.36 |
|
2018 |
Xiao T, Li W, Wang X, Xu H, Yang J, Wu Q, Huang Y, Geradts J, Jiang P, Fei T, Chi D, Zang C, Liao Q, Rennhack J, Andrechek E, et al. Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987050 DOI: 10.1073/Pnas.1722617115 |
0.666 |
|
2018 |
Hsu CC, Zhao D, Shi J, Peng D, Guan H, Li Y, Huang Y, Wen H, Li W, Li H, Shi X. Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity. Cell Discovery. 4: 28. PMID 29900004 DOI: 10.1038/S41421-018-0027-0 |
0.3 |
|
2018 |
Chen CH, Xiao T, Xu H, Jiang P, Meyer CA, Li W, Brown M, Liu XS. Improved design and analysis of CRISPR knockout screens. Bioinformatics (Oxford, England). PMID 29868757 DOI: 10.1093/Bioinformatics/Bty450 |
0.431 |
|
2018 |
Dhar SS, Zhao D, Lin T, Gu B, Pal K, Wu SJ, Alam H, Lv J, Yun K, Gopalakrishnan V, Flores ER, Northcott PA, Rajaram V, Li W, Shilatifard A, et al. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. Molecular Cell. PMID 29861161 DOI: 10.1016/J.Molcel.2018.04.028 |
0.337 |
|
2018 |
Park HJ, Ji P, Kim S, Xia Z, Rodriguez B, Li L, Su J, Chen K, Masamha CP, Baillat D, Fontes-Garfias CR, Shyu AB, Neilson JR, Wagner EJ, Li W. 3' UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk. Nature Genetics. PMID 29785014 DOI: 10.1038/S41588-018-0118-8 |
0.338 |
|
2018 |
Jeong M, Park HJ, Celik H, Ostrander EL, Reyes JM, Guzman A, Rodriguez B, Lei Y, Lee Y, Ding L, Guryanova OA, Li W, Goodell MA, Challen GA. Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo. Cell Reports. 23: 1-10. PMID 29617651 DOI: 10.1016/J.Celrep.2018.03.025 |
0.313 |
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2018 |
Park HJ, Kim S, Li W. Model-based analysis of competing-endogenous pathways (MACPath) in human cancers. Plos Computational Biology. 14: e1006074. PMID 29565967 DOI: 10.1371/Journal.Pcbi.1006074 |
0.366 |
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2018 |
Xi Y, Shi J, Li W, Tanaka K, Allton KL, Richardson D, Li J, Franco HL, Nagari A, Malladi VS, Coletta LD, Simper MS, Keyomarsi K, Shen J, Bedford MT, ... ... Li W, et al. Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes. Bmc Genomics. 19: 150. PMID 29458327 DOI: 10.1186/S12864-018-4533-0 |
0.336 |
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2018 |
Chen M, Lyu G, Han M, Nie H, Shen T, Chen W, Niu Y, Song Y, Li X, Li H, Chen X, Wang Z, Xia Z, Li W, Tian XL, et al. 3' UTR lengthening as a novel mechanism in regulating cellular senescence. Genome Research. PMID 29440281 DOI: 10.1101/Gr.224451.117 |
0.375 |
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2018 |
Hsu CC, Shi J, Yuan C, Zhao D, Jiang S, Lyu J, Wang X, Li H, Wen H, Li W, Shi X. Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer. Genes & Development. 32: 58-69. PMID 29437725 DOI: 10.1101/Gad.303784.117 |
0.34 |
|
2018 |
Jeong M, Huang X, Zhang X, Su J, Shamim MS, Bochkov ID, Reyes JM, Jung H, Heikamp EB, Aiden AP, Li W, Aiden EL, Goodell MA. Large DNA Methylation Canyons Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity Blood. 132: 534-534. DOI: 10.1182/Blood-2018-99-119485 |
0.33 |
|
2018 |
Zhu G, Luo H, Chen S, Lai Q, Guo Y, Guryanova OA, Qiu Y, Yang F, Li W, Nimer SD, Huang S, Xu M. Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis Blood. 132: 886-886. DOI: 10.1182/Blood-2018-99-112232 |
0.332 |
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2018 |
Luo H, Zhu G, Zha J, Yan B, Guo Y, Xu J, Lai Q, Xu B, Yang F, Li W, Qiu Y, Xu M, Huang S. Activation of Hottip lncrna Perturbs HSC Function Leading to AML like Disease in Mice Blood. 132: 3877-3877. DOI: 10.1182/Blood-2018-99-110218 |
0.365 |
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2018 |
Tovy A, Park HJ, Reyes JM, Guzman A, Rau RE, Jeffries A, Jonnathan M, Baple E, Crosby A, Petljak M, Lee-Six H, Wang H, Baozhong X, Sanders MA, Campbell PJ, ... ... Li W, et al. Mosaic DNMT3A Germline Mutation As a Model for Mutant DNMT3A Competitive Advantage in the Blood Lineage Blood. 132: 173-173. DOI: 10.1182/Blood-2018-173 |
0.313 |
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2017 |
Franco HL, Nagari A, Malladi V, Li W, Xi Y, Richardson D, Allton KL, Tanaka K, Li J, Murakami S, Keyomarsi K, Bedford MT, Shi X, Li W, Barton MC, et al. Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis. Genome Research. PMID 29273624 DOI: 10.1101/Gr.226019.117 |
0.348 |
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2017 |
Mi W, Guan H, Lyu J, Zhao D, Xi Y, Jiang S, Andrews FH, Wang X, Gagea M, Wen H, Tora L, Dent SYR, Kutateladze TG, Li W, Li H, et al. YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer. Nature Communications. 8: 1088. PMID 29057918 DOI: 10.1038/S41467-017-01173-4 |
0.357 |
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2017 |
Tencer AH, Cox KL, Di L, Bridgers JB, Lyu J, Wang X, Sims JK, Weaver TM, Allen HF, Zhang Y, Gatchalian J, Darcy MA, Gibson MD, Ikebe J, Li W, et al. Covalent Modifications of Histone H3K9 Promote Binding of CHD3. Cell Reports. 21: 455-466. PMID 29020631 DOI: 10.1016/J.Celrep.2017.09.054 |
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2017 |
Cao Q, Ma J, Chen CH, Xu H, Chen Z, Li W, Liu XS. CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments. Plos One. 12: e0184281. PMID 28873439 DOI: 10.1371/Journal.Pone.0184281 |
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2017 |
Lin X, Su J, Chen K, Rodriguez B, Li W. Sparse conserved under-methylated CpGs are associated with high-order chromatin structure. Genome Biology. 18: 163. PMID 28859663 DOI: 10.1186/S13059-017-1296-X |
0.319 |
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2017 |
Jiang Z, Yang J, Dai A, Wang Y, Li W, Xie Z. Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress. Bmc Genomics. 18: 638. PMID 28826393 DOI: 10.1186/S12864-017-3996-8 |
0.33 |
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2017 |
Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, Bedford MT, Sagum CA, Jung SY, Qin J, Tsai MJ, Tsai SY, Li W, Foulds CE, O'Malley BW. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. The Journal of Biological Chemistry. 292: 14456-14472. PMID 28717009 DOI: 10.1074/Jbc.M117.802074 |
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2017 |
Lei Y, Zhang X, Su J, Jeong M, Gundry MC, Huang YH, Zhou Y, Li W, Goodell MA. Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nature Communications. 8: 16026. PMID 28695892 DOI: 10.1038/Ncomms16026 |
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2017 |
Koppula P, Zhang Y, Shi J, Li W, Gan B. The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate. The Journal of Biological Chemistry. PMID 28630042 DOI: 10.1074/Jbc.M117.798405 |
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2017 |
Fei T, Chen Y, Xiao T, Li W, Cato L, Zhang P, Cotter MB, Bowden M, Lis RT, Zhao SG, Wu Q, Feng FY, Loda M, He HH, Liu XS, et al. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proceedings of the National Academy of Sciences of the United States of America. PMID 28611215 DOI: 10.1073/Pnas.1617467114 |
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2017 |
Oegema R, Baillat D, Schot R, van Unen LM, Brooks A, Kia SK, Hoogeboom AJM, Xia Z, Li W, Cesaroni M, Lequin MH, van Slegtenhorst M, Dobyns WB, de Coo IFM, Verheijen FW, et al. Human mutations in integrator complex subunits link transcriptome integrity to brain development. Plos Genetics. 13: e1006809. PMID 28542170 DOI: 10.1371/Journal.Pgen.1006809 |
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2017 |
Li MJ, Zhang J, Liang Q, Xuan C, Wu J, Jiang P, Li W, Zhu Y, Wang P, Fernandez D, Shen Y, Chen Y, Kocher JA, Yu Y, Sham PC, et al. Exploring genetic associations with ceRNA regulation in the human genome. Nucleic Acids Research. PMID 28472449 DOI: 10.1093/Nar/Gkx331 |
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2017 |
Routh A, Ji P, Jaworski E, Xia Z, Li W, Wagner EJ. Poly(A)-ClickSeq: click-chemistry for next-generation 3΄-end sequencing without RNA enrichment or fragmentation. Nucleic Acids Research. PMID 28449108 DOI: 10.1093/Nar/Gkx286 |
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2017 |
Dai F, Lee H, Zhang Y, Zhuang L, Yao H, Xi Y, Xiao ZD, You MJ, Li W, Su X, Gan B. BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response. Proceedings of the National Academy of Sciences of the United States of America. PMID 28275095 DOI: 10.1073/Pnas.1619588114 |
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2017 |
Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, Joseph JK, Wang X, Loh YE, Erb MA, Souza AL, Bradner JE, Shen L, Li W, Li H, et al. ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia. Nature. PMID 28241141 DOI: 10.1038/Nature21687 |
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2017 |
Gao W, Li W, Xiao T, Liu XS, Kaelin WG. Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL-/- clear cell renal carcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28082722 DOI: 10.1073/Pnas.1619726114 |
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2017 |
Xiao T, Li W, Wang X, Xu H, Wu Q, Jiang P, Yang J, Fei T, Zang C, Liao Q, Rennhack J, Andrechek E, Li N, Jeselsohn R, Liu SX, et al. Abstract PR06: CRISPR screens identified drivers of endocrine resistance and synthetic lethal vulnerabilities in breast cancer Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Pr06 |
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2016 |
Jain AK, Xi Y, McCarthy R, Allton K, Akdemir KC, Patel LR, Aronow B, Lin C, Li W, Yang L, Barton MC. LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56. Molecular Cell. 64: 967-981. PMID 27912097 DOI: 10.1016/J.Molcel.2016.10.039 |
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2016 |
Zhu S, Li W, Liu J, Chen CH, Liao Q, Xu P, Xu H, Xiao T, Cao Z, Peng J, Yuan P, Brown M, Liu XS, Wei W. Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library. Nature Biotechnology. PMID 27798563 DOI: 10.1038/Nbt.3715 |
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2016 |
Mamuya FA, Cano-Peñalver JL, Li WU, Rodriguez-Puyol D, Rodríguez-Puyol M, Brown D, de Frutos S, Lu HJ. ILK and Cytoskeletal Architecture: An Important Determinant of AQP2 Recycling and Subsequent Entry into the Exocytotic Pathway. American Journal of Physiology. Renal Physiology. ajprenal.00336.2016. PMID 27760768 DOI: 10.1152/Ajprenal.00336.2016 |
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2016 |
Giudice J, Xia Z, Li W, Cooper TA. Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1. Scientific Reports. 6: 35550. PMID 27759042 DOI: 10.1038/Srep35550 |
0.335 |
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2016 |
McNair C, Urbanucci A, Comstock CE, Augello MA, Goodwin JF, Launchbury R, Zhao SG, Schiewer MJ, Ertel A, Karnes J, Davicioni E, Wang L, Wang Q, Mills IG, Feng FY, ... Li W, et al. Cell cycle-coupled expansion of AR activity promotes cancer progression. Oncogene. PMID 27669432 DOI: 10.1038/Onc.2016.334 |
0.316 |
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2016 |
Li N, Li Y, Lv J, Zheng X, Wen H, Shen H, Zhu G, Chen TY, Dhar SS, Kan PY, Wang Z, Shiekhattar R, Shi X, Lan F, Chen K, ... Li W, et al. ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes. Molecular Cell. PMID 27477906 DOI: 10.1016/J.Molcel.2016.06.035 |
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2016 |
Zhang X, Su J, Jeong M, Ko M, Huang Y, Park HJ, Guzman A, Lei Y, Huang YH, Rao A, Li W, Goodell MA. DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells. Nature Genetics. PMID 27428748 DOI: 10.1038/Ng.3610 |
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2016 |
Ma J, Köster J, Qin Q, Hu S, Li W, Chen C, Cao Q, Wang J, Mei S, Liu Q, Xu H, Liu XS. CRISPR-DO for genome-wide CRISPR design and optimization. Bioinformatics (Oxford, England). PMID 27402906 DOI: 10.1093/Bioinformatics/Btw476 |
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2016 |
Li X, Wang W, Xi Y, Gao M, Tran M, Aziz KE, Qin J, Li W, Chen J. FOXR2 Interacts with MYC to Promote Its Transcriptional Activities and Tumorigenesis. Cell Reports. PMID 27346356 DOI: 10.1016/J.Celrep.2016.06.004 |
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Chen Z, Wang L, Wang Q, Li W. Histone modifications and chromatin organization in prostate cancer. Epigenomics. 2: 551-60. PMID 21318127 DOI: 10.2217/Epi.10.31 |
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2010 |
Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, Olshen A, Ballinger T, Zhou X, Forsberg KJ, Gu J, ... ... Li W, et al. Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nature Biotechnology. 28: 1097-105. PMID 20852635 DOI: 10.1038/Nbt.1682 |
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2010 |
Kim BJ, Li Y, Zhang J, Xi Y, Li Y, Yang T, Jung SY, Pan X, Chen R, Li W, Wang Y, Qin J. Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells. The Journal of Biological Chemistry. 285: 22784-92. PMID 20501661 DOI: 10.1074/Jbc.M110.134577 |
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2010 |
Lanz RB, Bulynko Y, Malovannaya A, Labhart P, Wang L, Li W, Qin J, Harper M, O'Malley BW. Global characterization of transcriptional impact of the SRC-3 coregulator. Molecular Endocrinology (Baltimore, Md.). 24: 859-72. PMID 20181721 DOI: 10.1210/Me.2009-0499 |
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2010 |
Guo XL, Ruan HB, Li Y, Gao X, Li W. Identification of a novel nonsense mutation on the Pax3 gene in ENU-derived white belly spotting mice and its genetic interaction with c-Kit. Pigment Cell & Melanoma Research. 23: 252-62. PMID 20095975 DOI: 10.1111/J.1755-148X.2010.00677.X |
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2009 |
Huang J, Chen T, Liu X, Jiang J, Li J, Li D, Liu XS, Li W, Kang J, Pei G. More synergetic cooperation of Yamanaka factors in induced pluripotent stem cells than in embryonic stem cells. Cell Research. 19: 1127-38. PMID 19736564 DOI: 10.1038/Cr.2009.106 |
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2009 |
Xi Y, Li W. BSMAP: whole genome bisulfite sequence MAPping program Bmc Bioinformatics. 10: 232-232. PMID 19635165 DOI: 10.1186/1471-2105-10-232 |
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2009 |
Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Lupien M, Wu T, Regan MM, Meyer CA, Carroll JS, Manrai AK, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell. 138: 245-56. PMID 19632176 DOI: 10.1016/J.Cell.2009.04.056 |
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2009 |
Xia X, Lemieux ME, Li W, Carroll JS, Brown M, Liu XS, Kung AL. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 106: 4260-5. PMID 19255431 DOI: 10.1073/Pnas.0810067106 |
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2009 |
Pathiraja T, Xi Y, Lee A, Santen R, Gannon F, Kaipparettu B, Chang J, Li W, Oesterreich S. Estrogen Deprivation Results in Altered DNA Methylation Profile in Breast Cancer Cells – Role in Endocrine Resistance? Cancer Research. 69: 5127-5127. DOI: 10.1158/0008-5472.Sabcs-09-5127 |
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2008 |
Yagi S, Hirabayashi K, Sato S, Li W, Takahashi Y, Hirakawa T, Wu G, Hattori N, Hattori N, Ohgane J, Tanaka S, Liu XS, Shiota K. DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression. Genome Research. 18: 1969-78. PMID 18971312 DOI: 10.1101/Gr.074070.107 |
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2008 |
Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS. Model-based analysis of ChIP-Seq (MACS). Genome Biology. 9: R137. PMID 18798982 DOI: 10.1186/Gb-2008-9-9-R137 |
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2008 |
Agoulnik IU, Bingman WE, Nakka M, Li W, Wang Q, Liu XS, Brown M, Weigel NL. Target gene-specific regulation of androgen receptor activity by p42/p44 mitogen-activated protein kinase. Molecular Endocrinology (Baltimore, Md.). 22: 2420-32. PMID 18787043 DOI: 10.1210/Me.2007-0481 |
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2008 |
Li W, Carroll JS, Brown M, Liu xS. xMAN: extreme MApping of OligoNucleotides. Bmc Genomics. 9: S20. PMID 18366610 DOI: 10.1186/1471-2164-9-S1-S20 |
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2008 |
Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, Carroll JS, Liu XS, Brown M. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell. 132: 958-70. PMID 18358809 DOI: 10.1016/J.Cell.2008.01.018 |
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2008 |
Johnson DS, Li W, Gordon DB, Bhattacharjee A, Curry B, Ghosh J, Brizuela L, Carroll JS, Brown M, Flicek P, Koch CM, Dunham I, Bieda M, Xu X, Farnham PJ, et al. Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Research. 18: 393-403. PMID 18258921 DOI: 10.1101/Gr.7080508 |
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Gottardo R, Li W, Johnson WE, Liu XS. A flexible and powerful bayesian hierarchical model for ChIP-Chip experiments. Biometrics. 64: 468-78. PMID 17888037 DOI: 10.1111/J.1541-0420.2007.00899.X |
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2007 |
O'Neil J, Tchinda J, Gutierrez A, Moreau L, Maser RS, Wong KK, Li W, McKenna K, Liu XS, Feng B, Neuberg D, Silverman L, DeAngelo DJ, Kutok JL, Rothstein R, et al. Alu elements mediate MYB gene tandem duplication in human T-ALL. The Journal of Experimental Medicine. 204: 3059-66. PMID 18070937 DOI: 10.1084/Jem.20071637 |
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2007 |
Song JS, Johnson WE, Zhu X, Zhang X, Li W, Manrai AK, Liu JS, Chen R, Liu XS. Model-based analysis of two-color arrays (MA2C). Genome Biology. 8: R178. PMID 17727723 DOI: 10.1186/Gb-2007-8-8-R178 |
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2007 |
Wang Q, Li W, Liu XS, Carroll JS, Jänne OA, Keeton EK, Chinnaiyan AM, Pienta KJ, Brown M. A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Molecular Cell. 27: 380-92. PMID 17679089 DOI: 10.1016/J.Molcel.2007.05.041 |
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Gorodkin J, Cirera S, Hedegaard J, Gilchrist MJ, Panitz F, Jørgensen C, Scheibye-Knudsen K, Arvin T, Lumholdt S, Sawera M, Green T, Nielsen BJ, Havgaard JH, Rosenkilde C, Wang J, ... ... Li W, et al. Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags. Genome Biology. 8: R45. PMID 17407547 DOI: 10.1186/Gb-2007-8-4-R45 |
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2007 |
Song JS, Maghsoudi K, Li W, Fox E, Quackenbush J, Shirley Liu X. Microarray blob-defect removal improves array analysis. Bioinformatics (Oxford, England). 23: 966-71. PMID 17332024 DOI: 10.1093/Bioinformatics/Btm043 |
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2006 |
Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, et al. Genome-wide analysis of estrogen receptor binding sites. Nature Genetics. 38: 1289-97. PMID 17013392 DOI: 10.1038/Ng1901 |
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Johnson WE, Li W, Meyer CA, Gottardo R, Carroll JS, Brown M, Liu XS. Model-based analysis of tiling-arrays for ChIP-chip. Proceedings of the National Academy of Sciences of the United States of America. 103: 12457-62. PMID 16895995 DOI: 10.1073/Pnas.0601180103 |
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Ji X, Li W, Song J, Wei L, Liu XS. CEAS: cis-regulatory element annotation system. Nucleic Acids Research. 34: W551-4. PMID 16845068 DOI: 10.1093/Nar/Gkl322 |
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Nelson EA, Walker SR, Li W, Liu XS, Frank DA. Identification of human STAT5-dependent gene regulatory elements based on interspecies homology. The Journal of Biological Chemistry. 281: 26216-24. PMID 16840779 DOI: 10.1074/Jbc.M605001200 |
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Palomero T, Odom DT, O'Neil J, Ferrando AA, Margolin A, Neuberg DS, Winter SS, Larson RS, Li W, Liu XS, Young RA, Look AT. Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia. Blood. 108: 986-92. PMID 16621969 DOI: 10.1182/Blood-2005-08-3482 |
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Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell. 122: 33-43. PMID 16009131 DOI: 10.1016/J.Cell.2005.05.008 |
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Li W, Meyer CA, Liu XS. A hidden Markov model for analyzing ChIP-chip experiments on genome tiling arrays and its application to p53 binding sequences. Bioinformatics (Oxford, England). 21: i274-82. PMID 15961467 DOI: 10.1093/Bioinformatics/Bti1046 |
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Li W, Shi J, Wang X, Han Y, Tong W, Ma L, Liu B, Cai B. Complete nucleotide sequence and organization of the naphthalene catabolic plasmid pND6-1 from Pseudomonas sp. strain ND6. Gene. 336: 231-40. PMID 15246534 DOI: 10.1016/J.Gene.2004.03.027 |
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Qin E, Zhu Q, Yu M, Fan B, Chang G, Si B, Yang B, Peng W, Jiang T, Liu B, Deng Y, Liu H, Zhang Y, Wang C, Li Y, ... ... Li W, ... ... Li W, et al. A complete sequence and comparative analysis of a SARS-associated virus (Isolate BJ01). Chinese Science Bulletin = Kexue Tongbao. 48: 941-948. PMID 32214698 DOI: 10.1007/Bf03184203 |
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Bao Q, Tian Y, Li W, Xu Z, Xuan Z, Hu S, Dong W, Yang J, Chen Y, Xue Y, Xu Y, Lai X, Huang L, Dong X, Ma Y, et al. A complete sequence of the T. tengcongensis genome. Genome Research. 12: 689-700. PMID 11997336 DOI: 10.1101/Gr.219302 |
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Yu J, Hu S, Wang J, Wong GK, Li S, Liu B, Deng Y, Dai L, Zhou Y, Zhang X, Cao M, Liu J, Sun J, Tang J, Chen Y, ... ... Li W, ... ... Li W, et al. A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (New York, N.Y.). 296: 79-92. PMID 11935017 DOI: 10.1126/Science.1068037 |
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