Sheng Ding, Ph.D. - Publications

Affiliations: 
Gladstone and UCSF, San Francisco, CA, United States 
 2003 Scripps Research Institute, La Jolla, La Jolla, CA, United States 

171 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhou W, He K, Wang C, Wang P, Wang D, Wang B, Geng H, Lian H, Ma T, Nie Y, Ding S. Pharmacologically inducing regenerative cardiac cells by small molecule drugs. Elife. 13. PMID 39651957 DOI: 10.7554/eLife.93405  0.779
2024 Liu S, Wang J, Wang X, Tan L, Liu T, Wang Y, Shi Y, Zhang Z, Ding S, Hou K, Zhang W, Li F, Meng X. Smart chitosan-based nanofibers for real-time monitoring and promotion of wound healing. International Journal of Biological Macromolecules. 136670. PMID 39442852 DOI: 10.1016/j.ijbiomac.2024.136670  0.374
2024 He K, Xue Q, Zhou W, Wang P, Hu X, Lin T, Chen N, Wang B, Ma T, Ding S. Extended pegRNAs enhance the editing capability of Prime editing. Trends in Biotechnology. PMID 39341743 DOI: 10.1016/j.tibtech.2024.09.004  0.694
2024 Abujarour R, Dinella J, Pribadi M, Fong LK, Denholtz M, Gutierrez A, Haynes M, Mahmood E, Lee TT, Ding S, Valamehr B. A chemical approach facilitates CRISPRa-only human iPSC generation and minimizes the number of targeted loci required. Future Science Oa. 10: FSO964. PMID 38817352 DOI: 10.2144/fsoa-2023-0257  0.748
2024 He J, Huo X, Pei G, Jia Z, Yan Y, Yu J, Qu H, Xie Y, Yuan J, Zheng Y, Hu Y, Shi M, You K, Li T, Ma T, ... ... Ding S, et al. Dual-role transcription factors stabilize intermediate expression levels. Cell. PMID 38631355 DOI: 10.1016/j.cell.2024.03.023  0.699
2023 Wei ZQ, Ding S, Yang YC. TYROBP-positive endothelial cell-derived TWEAK as a promoter of osteosarcoma progression: insights from single-cell omics. Frontiers in Oncology. 13: 1200203. PMID 37207157 DOI: 10.3389/fonc.2023.1200203  0.347
2023 Xu T, Qin Z, Wang X, Dong C, Driggers EM, Ding S. Reply to: GOT1 constrains T17 cell differentiation, while promoting iT cell differentiation. Nature. 614: E12-E14. PMID 36725991 DOI: 10.1038/s41586-022-05603-2  0.788
2022 Lin J, Xie M, Liu D, Gao Z, Zhao X, Ma H, Ding S, Li SM, Li S, Liu Y, Zhou F, Hu H, Chen T, Chen H, Xie M, et al. Characterization of light chain c-terminal extension sequence variant in one bispecific antibody. Frontiers in Chemistry. 10: 994472. PMID 36204149 DOI: 10.3389/fchem.2022.994472  0.302
2022 Li Y, Wang C, Gao H, Gu J, Zhang Y, Zhang Y, Xie M, Cheng X, Yang M, Zhang W, Li Y, He M, Xu H, Zhang H, Ji Q, ... ... Ding S, et al. KDM4 inhibitor SD49-7 attenuates leukemia stem cell KDM4A/MDM2/p21 axis. Theranostics. 12: 4922-4934. PMID 35836814 DOI: 10.7150/thno.71460  0.8
2022 Hu Y, Yang Y, Tan P, Zhang Y, Han M, Yu J, Zhang X, Jia Z, Wang D, Li Y, Ma T, Liu K, Ding S. Induction of mouse totipotent stem cells by a defined chemical cocktail. Nature. PMID 35728625 DOI: 10.1038/s41586-022-04967-9  0.819
2022 Wei X, Cai J, Wang C, Yang K, Ding S, Tian F, Lin S. Quaternized chitosan/cellulose composites as enhanced hemostatic and antibacterial sponges for wound healing. International Journal of Biological Macromolecules. PMID 35526773 DOI: 10.1016/j.ijbiomac.2022.05.007  0.312
2021 Desai RV, Chen X, Martin B, Chaturvedi S, Hwang DW, Li W, Yu C, Ding S, Thomson M, Singer RH, Coleman RA, Hansen MMK, Weinberger LS. A DNA-repair pathway can affect transcriptional noise to promote cell fate transitions. Science (New York, N.Y.). PMID 34301855 DOI: 10.1126/science.abc6506  0.377
2021 Zhou W, Ma T, Ding S. Non-viral approaches for somatic cell reprogramming into cardiomyocytes. Seminars in Cell & Developmental Biology. PMID 34238675 DOI: 10.1016/j.semcdb.2021.06.021  0.752
2021 Lu G, Zhang X, Zheng W, Sun J, Hua L, Xu L, Chu XJ, Ding S, Xiong W. Erratum for Lu et al., "Development of a Simple Assay To Identify and Evaluate Nucleotide Analogs against SARS-CoV-2 RNA-Dependent RNA Polymerase". Antimicrobial Agents and Chemotherapy. 65: e0082021. PMID 34137638 DOI: 10.1128/AAC.00820-21  0.447
2021 Wei X, Ding S, Liu S, Yang K, Cai J, Li F, Wang C, Lin S, Tian F. Polysaccharides-modified chitosan as improved and rapid hemostasis foam sponges. Carbohydrate Polymers. 264: 118028. PMID 33910719 DOI: 10.1016/j.carbpol.2021.118028  0.345
2020 Yu C, Ding S. Therapeutic strategies targeting somatic stem cells: Chemical approaches. Bioorganic & Medicinal Chemistry. 28: 115824. PMID 33126088 DOI: 10.1016/j.bmc.2020.115824  0.59
2020 Lu G, Zhang X, Zheng W, Sun J, Hua L, Xu L, Chu XJ, Ding S, Xiong W. Development of a simple assay to identify and evaluate nucleotide analogs against SARS-CoV-2 RNA-dependent RNA polymerase. Antimicrobial Agents and Chemotherapy. PMID 33122171 DOI: 10.1128/AAC.01508-20  0.466
2020 Telpoukhovskaia MA, Liu K, Sayed FA, Etchegaray JI, Xie M, Zhan L, Li Y, Zhou Y, Le D, Bahr BA, Bogyo M, Ding S, Gan L. Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia. Scientific Reports. 10: 13688. PMID 32792571 DOI: 10.1038/S41598-020-70534-9  0.543
2020 Perry JM, Tao F, Roy A, Lin T, He XC, Chen S, Lu X, Nemechek J, Ruan L, Yu X, Dukes D, Moran A, Pace J, Schroeder K, Zhao M, ... ... Ding S, et al. Overcoming Wnt-β-catenin dependent anticancer therapy resistance in leukaemia stem cells. Nature Cell Biology. PMID 32313104 DOI: 10.1038/S41556-020-0507-Y  0.365
2019 An Z, Liu P, Zheng J, Si C, Li T, Chen Y, Ma T, Zhang MQ, Zhou Q, Ding S. Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4. Cell Reports. 29: 1986-2000.e8. PMID 31722212 DOI: 10.1016/J.Celrep.2019.10.026  0.816
2019 Liu C, Hu X, Li Y, Lu W, Li W, Cao N, Zhu S, Cheng J, Ding S, Zhang M. Conversion of mouse fibroblasts into oligodendrocyte progenitor-like cells through a chemical approach. Journal of Molecular Cell Biology. PMID 30629188 DOI: 10.1093/Jmcb/Mjy088  0.852
2018 Li F, Xu Y, Liu B, Singh PK, Zhao W, Jin J, Han G, Scott AW, Dong X, Huo L, Ma L, Pool Pizzi M, Wang Y, Li Y, Harada K, ... ... Ding S, et al. YAP1-mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer - Rationale for the combination of YAP1 and CDK4/6 inhibitors in Esophageal Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30563933 DOI: 10.1158/1078-0432.Ccr-18-1029  0.384
2018 Hou L, Yang G, Tang S, Alcazar C, Joshi P, Strassberg Z, Kim M, Kawamura M, Woo YJ, Shrager J, Ding S, Huang NF. Small Molecule Derived From Carboxyethylpyrrole Protein Adducts Promotes Angiogenesis in a Mouse Model of Peripheral Arterial Disease. Journal of the American Heart Association. 7: e009234. PMID 30371212 DOI: 10.1161/Jaha.118.009234  0.729
2018 Liu Y, Yu C, Daley TP, Wang F, Cao WS, Bhate S, Lin X, Still C, Liu H, Zhao D, Wang H, Xie XS, Ding S, Wong WH, Wernig M, et al. CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming. Cell Stem Cell. PMID 30318302 DOI: 10.1016/J.Stem.2018.09.003  0.51
2018 Qin Y, Tang S, Zhen G, Ding Q, Ding S, Cao X. Bone-targeted delivery of TGF-β type 1 receptor inhibitor rescues uncoupled bone remodeling in Camurati-Engelmann disease. Annals of the New York Academy of Sciences. PMID 30091466 DOI: 10.1111/Nyas.13941  0.698
2018 Liu P, Chen M, Liu Y, Qi LS, Ding S. CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency. Cell Stem Cell. PMID 29358044 DOI: 10.1016/J.Stem.2017.12.001  0.545
2017 Yang B, Tang S, Ma C, Li ST, Shao GC, Dang B, DeGrado WF, Dong MQ, Wang PG, Ding S, Wang L. Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions. Nature Communications. 8: 2240. PMID 29269770 DOI: 10.1038/S41467-017-02409-Z  0.726
2017 Song S, Xie M, Scott AW, Jin J, Ma L, Dong X, Skinner HD, Johnson RL, Ding S, Ajani JA. A Novel YAP1 Inhibitor targets CSCs-enriched Radiation Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma. Molecular Cancer Therapeutics. PMID 29167315 DOI: 10.1158/1535-7163.Mct-17-0560  0.542
2017 Nakamura PA, Shimchuk AA, Tang S, Wang Z, DeGolier K, Ding S, Reh TA. Small molecule Photoregulin3 prevents retinal degeneration in the Rho(P23H) mouse model of retinitis pigmentosa. Elife. 6. PMID 29148976 DOI: 10.7554/Elife.30577  0.721
2017 Ajani JA, Estrella JS, Chen Q, Correa AM, Ma L, Scott AW, Jin J, Liu B, Xie M, Sudo K, Shiozaki H, Badgwell B, Weston B, Lee JH, Bhutani MS, ... ... Ding S, et al. Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors. British Journal of Cancer. PMID 29136404 DOI: 10.1038/Bjc.2017.388  0.377
2017 Wang C, Ward ME, Chen R, Liu K, Tracy TE, Chen X, Xie M, Sohn PD, Ludwig C, Meyer-Franke A, Karch CM, Ding S, Gan L. Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening. Stem Cell Reports. PMID 28966121 DOI: 10.1016/J.Stemcr.2017.08.019  0.538
2017 Xu T, Stewart KM, Wang X, Liu K, Xie M, Kyu Ryu J, Li K, Ma T, Wang H, Ni L, Zhu S, Cao N, Zhu D, Zhang Y, Akassoglou K, ... ... Ding S, et al. Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism. Nature. PMID 28783731 DOI: 10.1038/Nature23475  0.821
2017 Xie M, Tang S, Li K, Ding S. Pharmacological Reprogramming of Somatic Cells for Regenerative Medicine. Accounts of Chemical Research. PMID 28453285 DOI: 10.1021/Acs.Accounts.7B00020  0.853
2017 Shah BS, Chen M, Suzuki T, Embree M, Kong K, Lee CH, He L, Xiang L, Ahn JA, Ding S, Mao JJ. Pyrintegrin Induces Soft Tissue Formation by Transplanted or Endogenous Cells. Scientific Reports. 7: 36402. PMID 28128224 DOI: 10.1038/Srep36402  0.448
2017 Mao L, Nie B, Nie T, Hui X, Gao X, Lin X, Liu X, Xu Y, Tang X, Yuan R, Li K, Li P, Ding K, Wang Y, Xu A, ... ... Ding S, et al. Visualization and Quantification of Browning Using a Ucp1-2A-Luciferase Knock-in Mouse Model. Diabetes. 66: 407-417. PMID 28108609 DOI: 10.2337/Db16-0343  0.747
2017 Nie B, Nie T, Hui X, Gu P, Mao L, Li K, Yuan R, Zheng J, Wang H, Li K, Tang S, Zhang Y, Xu T, Xu A, Wu D, ... Ding S, et al. Brown Adipogenic Reprogramming Induced by a Small Molecule. Cell Reports. 18: 624-635. PMID 28099842 DOI: 10.1016/J.Celrep.2016.12.062  0.799
2017 Nakamura PA, Shimchuk AA, Tang S, Wang Z, DeGolier K, Ding S, Reh TA. Author response: Small molecule Photoregulin3 prevents retinal degeneration in the RhoP23H mouse model of retinitis pigmentosa Elife. DOI: 10.7554/Elife.30577.015  0.707
2016 Nakamura PA, Tang S, Shimchuk AA, Ding S, Reh TA. Potential of Small Molecule-Mediated Reprogramming of Rod Photoreceptors to Treat Retinitis Pigmentosa. Investigative Ophthalmology & Visual Science. 57: 6407-6415. PMID 27893103 DOI: 10.1167/Iovs.16-20177  0.725
2016 Mohamed TM, Stone NR, Berry EC, Radzinsky E, Huang Y, Pratt K, Ang YS, Yu P, Wang H, Tang S, Magnitsky S, Ding S, Ivey KN, Srivastava D. Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming. Circulation. PMID 27834668 DOI: 10.1161/Circulationaha.116.024692  0.77
2016 Nie T, Hui X, Mao L, Nie B, Li K, Sun W, Gao X, Tang X, Xu Y, Jiang B, Tu Z, Li P, Ding K, Han W, Zhang S, ... ... Ding S, et al. Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis. Scientific Reports. 6: 36382. PMID 27805061 DOI: 10.1038/Srep36382  0.741
2016 Saydaminova K, Strauss R, Xie M, Bartek J, Richter M, van Rensburg R, Drescher C, Ehrhardt A, Ding S, Lieber A. Sensitizing ovarian cancer cells to chemotherapy by interfering with pathways that are involved in the formation of cancer stem cells. Cancer Biology & Therapy. 0. PMID 27574825 DOI: 10.1080/15384047.2016.1219819  0.473
2016 Liu K, Yu C, Xie M, Li K, Ding S. Chemical Modulation of Cell Fate in Stem Cell Therapeutics and Regenerative Medicine. Cell Chemical Biology. PMID 27524294 DOI: 10.1016/J.Chembiol.2016.07.007  0.771
2016 Zhang M, Lin YH, Sun YJ, Zhu S, Zheng J, Liu K, Cao N, Li K, Huang Y, Ding S. Pharmacological Reprogramming of Fibroblasts into Neural Stem Cells by Signaling-Directed Transcriptional Activation. Cell Stem Cell. PMID 27133794 DOI: 10.1016/J.Stem.2016.03.020  0.866
2016 Cao N, Huang Y, Zheng J, Spencer CI, Zhang Y, Fu JD, Nie B, Xie M, Zhang M, Wang H, Ma T, Xu T, Shi G, Srivastava D, Ding S. Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science (New York, N.Y.). PMID 27127239 DOI: 10.1126/science.aaf1502  0.84
2016 Zhang Y, Cao N, Huang Y, Spencer CI, Fu JD, Yu C, Liu K, Nie B, Xu T, Li K, Xu S, Bruneau BG, Srivastava D, Ding S. Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts. Cell Stem Cell. 18: 368-381. PMID 26942852 DOI: 10.1016/J.Stem.2016.02.001  0.829
2016 Zhu S, Russ HA, Wang X, Zhang M, Ma T, Xu T, Tang S, Hebrok M, Ding S. Human pancreatic beta-like cells converted from fibroblasts. Nature Communications. 7: 10080. PMID 26733021 DOI: 10.1038/Ncomms10080  0.834
2016 Li W, Wei W, Ding S. TGF-β Signaling in Stem Cell Regulation. Methods in Molecular Biology (Clifton, N.J.). 1344: 137-45. PMID 26520122 DOI: 10.1007/978-1-4939-2966-5_8  0.8
2015 Chang J, Wang Y, Shao L, Laberge RM, Demaria M, Campisi J, Janakiraman K, Sharpless NE, Ding S, Feng W, Luo Y, Wang X, Aykin-Burns N, Krager K, Ponnappan U, et al. Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. Nature Medicine. PMID 26657143 DOI: 10.1038/Nm.4010  0.537
2015 Ma T, Li J, Xu Y, Yu C, Xu T, Wang H, Liu K, Cao N, Nie BM, Zhu SY, Xu S, Li K, Wei WG, Wu Y, Guan KL, ... Ding S, et al. Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming. Nature Cell Biology. PMID 26502054 DOI: 10.1038/Ncb3256  0.778
2015 Tang S, Xie M, Cao N, Ding S. Patient-Specific Induced Pluripotent Stem Cells for Disease Modeling and Phenotypic Drug Discovery. Journal of Medicinal Chemistry. PMID 26322868 DOI: 10.1021/Acs.Jmedchem.5B00789  0.838
2015 Zhu S, Wang H, Ding S. Reprogramming fibroblasts toward cardiomyocytes, neural stem cells and hepatocytes by cell activation and signaling-directed lineage conversion. Nature Protocols. 10: 959-73. PMID 26042385 DOI: 10.1038/Nprot.2015.059  0.829
2015 Nie T, Hui X, Gao X, Nie B, Mao L, Tang X, Yuan R, Li K, Li P, Xu A, Liu P, Ding S, Han W, Cooper GJ, Wu D. Conversion of non-adipogenic fibroblasts into adipocytes by a defined hormone mixture. The Biochemical Journal. 467: 487-94. PMID 25730278 DOI: 10.1042/Bj20140727  0.785
2015 Yu C, Liu Y, Ma T, Liu K, Xu S, Zhang Y, Liu H, La Russa M, Xie M, Ding S, Qi LS. Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell. 16: 142-7. PMID 25658371 DOI: 10.1016/J.Stem.2015.01.003  0.817
2015 Chandrasekar T, Yang JC, Xie M, Ding S, Rosenfeld MG, Evans CP. Abstract 3453: Effect of a histone DNA demethylase on castration resistant prostate cancer cell lines, a potential therapeutic application Cancer Research. 75: 3453-3453. DOI: 10.1158/1538-7445.Am2015-3453  0.454
2015 Hu M, Hong WX, Xie M, Tang S, Rennert R, Walmsley G, Maan Z, Zimmermann A, Gurtner G, Giaccia A, Lorenz P, Ding S, Longaker M. Abstract 178 Plastic and Reconstructive Surgery. 135: 124-125. DOI: 10.1097/01.Prs.0000465626.54269.69  0.668
2015 Saydaminova K, Strauss R, Xie M, Dreshner C, Ding S, Lieber A. 458. Sensitizing Ovarian Cancer Cells To Chemotherapy By Interfering With Pathways That Are Involved in the Formation and Maintenance of Cancer Stem Cells Molecular Therapy. 23: S182. DOI: 10.1016/S1525-0016(16)34067-9  0.435
2015 Chandrasekar T, Yang JC, Xie M, Ding S, Rosenfeld MG, Evans CP. MP46-07 EFFECT OF A HISTONE DNA DEMETHYLASE ON CRPC CELL LINES, A POTENTIAL THERAPEUTIC APPLICATION. Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.1570  0.454
2014 Yu C, Liu K, Tang S, Ding S. Chemical approaches to cell reprogramming. Current Opinion in Genetics & Development. 28: 50-6. PMID 25461450 DOI: 10.1016/J.Gde.2014.09.006  0.84
2014 Dimmeler S, Ding S, Rando TA, Trounson A. Translational strategies and challenges in regenerative medicine. Nature Medicine. 20: 814-21. PMID 25100527 DOI: 10.1038/Nm.3627  0.429
2014 Ding S, Song M, Sim BC, Gu C, Podust VN, Wang CW, McLaughlin B, Shah TP, Lax R, Gast R, Sharan R, Vasek A, Hartman MA, Deniston C, Srinivas P, et al. Multivalent antiviral XTEN-peptide conjugates with long in vivo half-life and enhanced solubility. Bioconjugate Chemistry. 25: 1351-9. PMID 24932887 DOI: 10.1021/bc500215m  0.464
2014 Jin C, Yang L, Xie M, Lin C, Merkurjev D, Yang JC, Tanasa B, Oh S, Zhang J, Ohgi KA, Zhou H, Li W, Evans CP, Ding S, Rosenfeld MG. Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens. Proceedings of the National Academy of Sciences of the United States of America. 111: 9235-40. PMID 24928520 DOI: 10.1073/Pnas.1404303111  0.775
2014 Yu Y, Ding S, Liang Y, Zheng Y, Li W, Yang L, Zheng X, Jiang J. Expression of ERCC1, TYMS, TUBB3, RRM1 and TOP2A in patients with esophageal squamous cell carcinoma: A hierarchical clustering analysis. Experimental and Therapeutic Medicine. 7: 1578-1582. PMID 24926347 DOI: 10.3892/etm.2014.1659  0.448
2014 Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S. Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature. 508: 93-7. PMID 24572354 DOI: 10.1038/Nature13020  0.737
2014 Wang H, Cao N, Spencer CI, Nie B, Ma T, Xu T, Zhang Y, Wang X, Srivastava D, Ding S. Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. Cell Reports. 6: 951-60. PMID 24561253 DOI: 10.1016/J.Celrep.2014.01.038  0.823
2014 Zhao JJ, Ouyang H, Luo J, Patel S, Xue Y, Quach J, Sfeir N, Zhang M, Fu X, Ding S, Chen S, Zhang K. Induction of retinal progenitors and neurons from mammalian Müller glia under defined conditions. The Journal of Biological Chemistry. 289: 11945-51. PMID 24523410 DOI: 10.1074/Jbc.M113.532671  0.539
2014 Li K, Zhu S, Russ HA, Xu S, Xu T, Zhang Y, Ma T, Hebrok M, Ding S. Small molecules facilitate the reprogramming of mouse fibroblasts into pancreatic lineages. Cell Stem Cell. 14: 228-36. PMID 24506886 DOI: 10.1016/J.Stem.2014.01.006  0.84
2014 Xie M, Cao N, Ding S. Small molecules for cell reprogramming and heart repair: progress and perspective. Acs Chemical Biology. 9: 34-44. PMID 24372513 DOI: 10.1021/Cb400865W  0.728
2014 Zhu S, Ambasudhan R, Sun W, Kim HJ, Talantova M, Wang X, Zhang M, Zhang Y, Laurent T, Parker J, Kim HS, Zaremba JD, Saleem S, Sanz-Blasco S, Masliah E, ... ... Ding S, et al. Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells. Cell Research. 24: 126-9. PMID 24296783 DOI: 10.1038/Cr.2013.156  0.845
2014 Passegue E, Teitell M, Ding S, Rando T, Belmonte JCI, Ramalho-Santos M, Terzic A, Brunet A, Chandel NS, Bonnet D, Jasper H. Stem cell energetics Cell Metabolism. 20: 922-925. DOI: 10.1016/J.Cmet.2014.11.007  0.442
2013 Fu JD, Stone NR, Liu L, Spencer CI, Qian L, Hayashi Y, Delgado-Olguin P, Ding S, Bruneau BG, Srivastava D. Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state. Stem Cell Reports. 1: 235-47. PMID 24319660 DOI: 10.1016/J.Stemcr.2013.07.005  0.483
2013 Calvanese V, Chavez L, Laurent T, Ding S, Verdin E. Dual-color HIV reporters trace a population of latently infected cells and enable their purification. Virology. 446: 283-92. PMID 24074592 DOI: 10.1016/J.Virol.2013.07.037  0.77
2013 Lu B, Morgans CW, Girman S, Luo J, Zhao J, Du H, Lim S, Ding S, Svendsen C, Zhang K, Wang S. Neural Stem Cells Derived by Small Molecules Preserve Vision. Translational Vision Science & Technology. 2: 1. PMID 24049711 DOI: 10.1167/Tvst.2.1.1  0.572
2013 Li W, Li K, Wei W, Ding S. Chemical approaches to stem cell biology and therapeutics. Cell Stem Cell. 13: 270-83. PMID 24012368 DOI: 10.1016/J.Stem.2013.08.002  0.855
2013 Li W, Ding S. Converting mouse epiblast stem cells into mouse embryonic stem cells by using small molecules. Methods in Molecular Biology (Clifton, N.J.). 1074: 31-7. PMID 23975803 DOI: 10.1007/978-1-62703-628-3_3  0.715
2013 Yu Y, Ding S, Zheng Y, Li W, Yang L, Zheng X, Liu X, Jiang J. Esophageal rupture caused by explosion of an automobile tire tube: a case report. Journal of Medical Case Reports. 7: 211. PMID 23972148 DOI: 10.1186/1752-1947-7-211  0.407
2013 Lin C, Yu C, Ding S. Toward directed reprogramming through exogenous factors. Current Opinion in Genetics & Development. 23: 519-25. PMID 23932127 DOI: 10.1016/J.Gde.2013.06.002  0.836
2013 Wang F, Scoville D, He XC, Mahe MM, Box A, Perry JM, Smith NR, Lei NY, Davies PS, Fuller MK, Haug JS, McClain M, Gracz AD, Ding S, Stelzner M, et al. Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay. Gastroenterology. 145: 383-95.e1-21. PMID 23644405 DOI: 10.1053/J.Gastro.2013.04.050  0.42
2013 Xu T, Zhang M, Laurent T, Xie M, Ding S. Concise review: chemical approaches for modulating lineage-specific stem cells and progenitors. Stem Cells Translational Medicine. 2: 355-61. PMID 23580542 DOI: 10.5966/Sctm.2012-0172  0.872
2013 Li J, Huang NF, Zou J, Laurent TJ, Lee JC, Okogbaa J, Cooke JP, Ding S. Conversion of human fibroblasts to functional endothelial cells by defined factors. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1366-75. PMID 23520160 DOI: 10.1161/Atvbaha.112.301167  0.821
2013 Ma T, Xie M, Laurent T, Ding S. Progress in the reprogramming of somatic cells. Circulation Research. 112: 562-74. PMID 23371904 DOI: 10.1161/Circresaha.111.249235  0.862
2013 Li W, Jiang K, Wei W, Shi Y, Ding S. Chemical approaches to studying stem cell biology. Cell Research. 23: 81-91. PMID 23266890 DOI: 10.1038/Cr.2012.182  0.857
2013 Zhao J, Sun W, Cho HM, Ouyang H, Li W, Lin Y, Do J, Zhang L, Ding S, Liu Y, Lu P, Zhang K. Integration and long distance axonal regeneration in the central nervous system from transplanted primitive neural stem cells. The Journal of Biological Chemistry. 288: 164-8. PMID 23155053 DOI: 10.1074/Jbc.M112.433607  0.61
2013 Wang F, Scoville D, He X, Box AC, Mahe MM, Smith NR, Davies P, Gracz AD, Fuller MK, Haug JS, McClain M, Magness ST, Wong MH, Ding S, Helmrath MA, et al. 402 Isolation and Characterization of Intestinal Stem Cells Using Combinatorial Surface Markers and Robust Clonal Assay Gastroenterology. 144: S-78. DOI: 10.1016/S0016-5085(13)60287-5  0.445
2012 Zhang Y, Li W, Laurent T, Ding S. Small molecules, big roles -- the chemical manipulation of stem cell fate and somatic cell reprogramming. Journal of Cell Science. 125: 5609-20. PMID 23420199 DOI: 10.1242/Jcs.096032  0.875
2012 Nie B, Wang H, Laurent T, Ding S. Cellular reprogramming: a small molecule perspective. Current Opinion in Cell Biology. 24: 784-92. PMID 22959962 DOI: 10.1016/J.Ceb.2012.08.010  0.862
2012 Westenskow PD, Moreno SK, Krohne TU, Kurihara T, Zhu S, Zhang ZN, Zhao T, Xu Y, Ding S, Friedlander M. Using flow cytometry to compare the dynamics of photoreceptor outer segment phagocytosis in iPS-derived RPE cells. Investigative Ophthalmology & Visual Science. 53: 6282-90. PMID 22871841 DOI: 10.1167/Iovs.12-9721  0.761
2012 Liu K, Ding S. Target practice: modeling tumors with stem cells. Cell. 149: 1185-7. PMID 22682241 DOI: 10.1016/J.Cell.2012.05.019  0.609
2012 Kim J, Ambasudhan R, Ding S. Direct lineage reprogramming to neural cells. Current Opinion in Neurobiology. 22: 778-84. PMID 22652035 DOI: 10.1016/J.Conb.2012.05.001  0.838
2012 Krohne TU, Westenskow PD, Kurihara T, Friedlander DF, Lehmann M, Dorsey AL, Li W, Zhu S, Schultz A, Wang J, Siuzdak G, Ding S, Friedlander M. Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells. Stem Cells Translational Medicine. 1: 96-109. PMID 22532929 DOI: 10.5966/Sctm.2011-0057  0.771
2012 Li H, Zhou H, Wang D, Qiu J, Zhou Y, Li X, Rosenfeld MG, Ding S, Fu XD. Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery. Proceedings of the National Academy of Sciences of the United States of America. 109: 4609-14. PMID 22396588 DOI: 10.1073/Pnas.1200305109  0.341
2012 Li W, Jiang K, Ding S. Concise review: A chemical approach to control cell fate and function. Stem Cells (Dayton, Ohio). 30: 61-8. PMID 22028211 DOI: 10.1002/Stem.768  0.74
2012 Li L, Wang F, Scoville D, Box AC, Haug J, Gracz AD, Magness ST, Wong MH, Yu J, Ding S, He X. Mo2086 Characterizing Intestinal Stem Cells Using Robust Clonal Assay and Surface Markers Gastroenterology. 143: e27. DOI: 10.1053/J.Gastro.2012.07.087  0.46
2011 Efe JA, Yuan X, Jiang K, Ding S. Development unchained: how cellular reprogramming is redefining our view of cell fate and identity. Science Progress. 94: 298-322. PMID 22026150 DOI: 10.3184/003685011X13131588500975  0.857
2011 Perry JM, He XC, Sugimura R, Grindley JC, Haug JS, Ding S, Li L. Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion. Genes & Development. 25: 1928-42. PMID 21890648 DOI: 10.1101/Gad.17421911  0.481
2011 Liu J, Johnson K, Li J, Piamonte V, Steffy BM, Hsieh MH, Ng N, Zhang J, Walker JR, Ding S, Muneoka K, Wu X, Glynne R, Schultz PG. Regenerative phenotype in mice with a point mutation in transforming growth factor beta type I receptor (TGFBR1). Proceedings of the National Academy of Sciences of the United States of America. 108: 14560-5. PMID 21841138 DOI: 10.1073/Pnas.1111056108  0.74
2011 Ambasudhan R, Talantova M, Coleman R, Yuan X, Zhu S, Lipton SA, Ding S. Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell. 9: 113-8. PMID 21802386 DOI: 10.1016/j.stem.2011.07.002  0.833
2011 Zhang K, Ding S. Stem cells and eye development. The New England Journal of Medicine. 365: 370-2. PMID 21793749 DOI: 10.1056/Nejmcibr1105280  0.53
2011 Wang Q, Xu X, Li J, Liu J, Gu H, Zhang R, Chen J, Kuang Y, Fei J, Jiang C, Wang P, Pei D, Ding S, Xie X. Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells. Cell Research. 21: 1424-35. PMID 21727907 DOI: 10.1038/Cr.2011.108  0.666
2011 Efe JA, Ding S. The evolving biology of small molecules: controlling cell fate and identity. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2208-21. PMID 21727126 DOI: 10.1098/Rstb.2011.0006  0.867
2011 Shen Y, Shi C, Wei W, Yu W, Li W, Yang Y, Xu J, Ying W, Sui X, Fang L, Lin W, Yang H, Ding S, Shen H, Shi Y, et al. The heterogeneity and dynamic equilibrium of rat embryonic stem cells. Cell Research. 21: 1143-7. PMID 21670743 DOI: 10.1038/Cr.2011.98  0.811
2011 Xu T, Wang X, Zhong B, Nurieva RI, Ding S, Dong C. Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t protein. The Journal of Biological Chemistry. 286: 22707-10. PMID 21566134 DOI: 10.1074/Jbc.C111.250407  0.381
2011 Efe JA, Ding S. Reprogramming, transdifferentiation and the shifting landscape of cellular identity. Cell Cycle (Georgetown, Tex.). 10: 1886-7. PMID 21558807 DOI: 10.4161/Cc.10.12.15591  0.785
2011 Li W, Sun W, Zhang Y, Wei W, Ambasudhan R, Xia P, Talantova M, Lin T, Kim J, Wang X, Kim WR, Lipton SA, Zhang K, Ding S. Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 8299-304. PMID 21525408 DOI: 10.1073/Pnas.1014041108  0.846
2011 Kim J, Efe JA, Zhu S, Talantova M, Yuan X, Wang S, Lipton SA, Zhang K, Ding S. Direct reprogramming of mouse fibroblasts to neural progenitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 7838-43. PMID 21521790 DOI: 10.1073/Pnas.1103113108  0.859
2011 Zhu S, Wei W, Ding S. Chemical strategies for stem cell biology and regenerative medicine. Annual Review of Biomedical Engineering. 13: 73-90. PMID 21513460 DOI: 10.1146/Annurev-Bioeng-071910-124715  0.872
2011 Li W, Ding S. Human pluripotent stem cells: decoding the naïve state. Science Translational Medicine. 3: 76ps10. PMID 21451122 DOI: 10.1126/Scitranslmed.3000996  0.696
2011 Yuan X, Wan H, Zhao X, Zhu S, Zhou Q, Ding S. Brief report: combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts. Stem Cells (Dayton, Ohio). 29: 549-53. PMID 21425417 DOI: 10.1002/Stem.594  0.838
2011 Zhu S, Ma T, Li J, Ding S. Recent advances in chemically induced reprogramming. Cell Cycle (Georgetown, Tex.). 10: 871-2. PMID 21368574 DOI: 10.4161/Cc.10.6.15035  0.864
2011 Efe JA, Hilcove S, Kim J, Zhou H, Ouyang K, Wang G, Chen J, Ding S. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nature Cell Biology. 13: 215-22. PMID 21278734 DOI: 10.1038/Ncb2164  0.836
2011 Yuan X, Li W, Ding S. Small molecules in cellular reprogramming and differentiation. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 67: 253-66. PMID 21141734 DOI: 10.1007/978-3-7643-8989-5_13  0.802
2010 Zhu S, Li W, Zhou H, Wei W, Ambasudhan R, Lin T, Kim J, Zhang K, Ding S. Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell. 7: 651-5. PMID 21112560 DOI: 10.1016/J.Stem.2010.11.015  0.793
2010 Zhou H, Li W, Zhu S, Joo JY, Do JT, Xiong W, Kim JB, Zhang K, Schöler HR, Ding S. Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. The Journal of Biological Chemistry. 285: 29676-80. PMID 20705612 DOI: 10.1074/Jbc.C110.150599  0.863
2010 Abujarour R, Efe J, Ding S. Genome-wide gain-of-function screen identifies novel regulators of pluripotency. Stem Cells (Dayton, Ohio). 28: 1487-97. PMID 20629179 DOI: 10.1002/Stem.472  0.859
2010 Lian I, Kim J, Okazawa H, Zhao J, Zhao B, Yu J, Chinnaiyan A, Israel MA, Goldstein LS, Abujarour R, Ding S, Guan KL. The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes & Development. 24: 1106-18. PMID 20516196 DOI: 10.1101/Gad.1903310  0.8
2010 Zhou H, Ding S. Evolution of induced pluripotent stem cell technology. Current Opinion in Hematology. 17: 276-80. PMID 20442654 DOI: 10.1097/Moh.0B013E328339F2Ee  0.563
2010 Yanes O, Clark J, Wong DM, Patti GJ, Sánchez-Ruiz A, Benton HP, Trauger SA, Desponts C, Ding S, Siuzdak G. Metabolic oxidation regulates embryonic stem cell differentiation. Nature Chemical Biology. 6: 411-7. PMID 20436487 DOI: 10.1038/Nchembio.364  0.843
2010 Xu Y, Zhu X, Hahm HS, Wei W, Hao E, Hayek A, Ding S. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proceedings of the National Academy of Sciences of the United States of America. 107: 8129-34. PMID 20406903 DOI: 10.1073/Pnas.1002024107  0.829
2010 Li W, Ding S. Generation of novel rat and human pluripotent stem cells by reprogramming and chemical approaches. Methods in Molecular Biology (Clifton, N.J.). 636: 293-300. PMID 20336530 DOI: 10.1007/978-1-60761-691-7_18  0.692
2010 Desponts C, Ding S. Using small molecules to improve generation of induced pluripotent stem cells from somatic cells. Methods in Molecular Biology (Clifton, N.J.). 636: 207-18. PMID 20336525 DOI: 10.1007/978-1-60761-691-7_13  0.816
2010 Li W, Ding S. Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming. Trends in Pharmacological Sciences. 31: 36-45. PMID 19896224 DOI: 10.1016/J.Tips.2009.10.002  0.75
2009 Li W, Zhou H, Abujarour R, Zhu S, Young Joo J, Lin T, Hao E, Schöler HR, Hayek A, Ding S. Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells (Dayton, Ohio). 27: 2992-3000. PMID 19839055 DOI: 10.1002/Stem.240  0.85
2009 Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S. A chemical platform for improved induction of human iPSCs. Nature Methods. 6: 805-8. PMID 19838168 DOI: 10.1038/Nmeth.1393  0.816
2009 Brill LM, Xiong W, Lee KB, Ficarro SB, Crain A, Xu Y, Terskikh A, Snyder EY, Ding S. Phosphoproteomic analysis of human embryonic stem cells. Cell Stem Cell. 5: 204-13. PMID 19664994 DOI: 10.1016/J.Stem.2009.06.002  0.76
2009 Abujarour R, Ding S. Induced pluripotent stem cells free of exogenous reprogramming factors. Genome Biology. 10: 220. PMID 19439061 DOI: 10.1186/Gb-2009-10-5-220  0.811
2009 Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, Trauger S, Bien G, Yao S, Zhu Y, Siuzdak G, Schöler HR, Duan L, Ding S. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell. 4: 381-4. PMID 19398399 DOI: 10.1016/J.Stem.2009.04.005  0.806
2009 Wu D, Pang Y, Ke Y, Yu J, He Z, Tautz L, Mustelin T, Ding S, Huang Z, Feng GS. A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. Plos One. 4: e4914. PMID 19290061 DOI: 10.1371/Journal.Pone.0004914  0.523
2009 Li W, Wei W, Zhu S, Zhu J, Shi Y, Lin T, Hao E, Hayek A, Deng H, Ding S. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell. 4: 16-9. PMID 19097958 DOI: 10.1016/J.Stem.2008.11.014  0.804
2009 Yang W, Wei W, Shi C, Zhu J, Ying W, Shen Y, Ye X, Fang L, Duo S, Che J, Shen H, Ding S, Deng H. Pluripotin combined with leukemia inhibitory factor greatly promotes the derivation of embryonic stem cell lines from refractory strains. Stem Cells (Dayton, Ohio). 27: 383-9. PMID 19056907 DOI: 10.1634/Stemcells.2008-0974  0.78
2008 Shi Y, Desponts C, Do JT, Hahm HS, Schöler HR, Ding S. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell. 3: 568-74. PMID 18983970 DOI: 10.1016/J.Stem.2008.10.004  0.868
2008 Shi Y, Do JT, Desponts C, Hahm HS, Schöler HR, Ding S. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell. 2: 525-8. PMID 18522845 DOI: 10.1016/J.Stem.2008.05.011  0.815
2008 Xu Y, Shi Y, Ding S. A chemical approach to stem-cell biology and regenerative medicine. Nature. 453: 338-44. PMID 18480815 DOI: 10.1038/Nature07042  0.694
2007 Qyang Y, Martin-Puig S, Chiravuri M, Chen S, Xu H, Bu L, Jiang X, Lin L, Granger A, Moretti A, Caron L, Wu X, Clarke J, Taketo MM, Laugwitz KL, ... ... Ding S, et al. The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell. 1: 165-79. PMID 18371348 DOI: 10.1016/J.Stem.2007.05.018  0.637
2007 Lee J, Wu X, Pasca di Magliano M, Peters EC, Wang Y, Hong J, Hebrok M, Ding S, Cho CY, Schultz PG. A small-molecule antagonist of the hedgehog signaling pathway. Chembiochem : a European Journal of Chemical Biology. 8: 1916-9. PMID 17886323 DOI: 10.1002/Cbic.200700403  0.781
2007 Ambasudhan R, Ding S. An "Orphan" Finds a Home in NSC Regulation Chemistry and Biology. 14: 974-975. PMID 17884628 DOI: 10.1016/J.Chembiol.2007.09.001  0.805
2007 Chen S, Takanashi S, Zhang Q, Xiong W, Zhu S, Peters EC, Ding S, Schultz PG. Reversine increases the plasticity of lineage-committed mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 10482-7. PMID 17566101 DOI: 10.1073/Pnas.0704360104  0.82
2007 Zhao Y, Ding S. A high-throughput siRNA library screen identifies osteogenic suppressors in human mesenchymal stem cells Proceedings of the National Academy of Sciences of the United States of America. 104: 9673-9678. PMID 17535907 DOI: 10.1073/pnas.0703407104  0.446
2007 Emre N, Coleman R, Ding S. A chemical approach to stem cell biology Current Opinion in Chemical Biology. 11: 252-258. PMID 17493865 DOI: 10.1016/J.Cbpa.2007.04.024  0.867
2007 Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S. Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 104: 7444-8. PMID 17460038 DOI: 10.1073/Pnas.0702136104  0.779
2007 Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S. Erratum: Small-molecule synergist of the Wnt/β-catenin signaling pathway (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 18, (7444-7448) DOI: 10.1073/pnas.0702136104) Proceedings of the National Academy of Sciences of the United States of America. 104. DOI: 10.1073/Pnas.0705165104  0.752
2007 Clark JH, Ding S. Chemically-Defined Culture of Human Embryonic Stem Cells Human Embryonic Stem Cells: the Practical Handbook. 81-90. DOI: 10.1002/9780470511619.ch6  0.413
2007 Clark J, Xu Y, Hilcove S, Ding S. Exploring Stem Cell Biology with Small Molecules and Functional Genomics Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine. 187-206. DOI: 10.1002/9780470199138.ch8  0.84
2006 Wu TY, Ding S. Applying chemical tools to the discovery of novel regenerative medicine. Drug Discovery Today. Technologies. 3: 255-60. PMID 24980526 DOI: 10.1016/J.Ddtec.2006.09.001  0.699
2006 Chen S, Do JT, Zhang Q, Yao S, Yan F, Peters EC, Schöler HR, Schultz PG, Ding S. Self-renewal of embryonic stem cells by a small molecule. Proceedings of the National Academy of Sciences of the United States of America. 103: 17266-71. PMID 17088537 DOI: 10.1073/Pnas.0608156103  0.848
2006 Clark J, Ding S. Generation of RNAi libraries for high-throughput screens. Journal of Biomedicine & Biotechnology. 2006: 45716. PMID 17057364 DOI: 10.1155/Jbb/2006/45716  0.657
2006 Belvindrah R, Nalbant P, Ding S, Wu C, Bokoch GM, Müller U. Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development. Molecular and Cellular Neurosciences. 33: 109-25. PMID 16914328 DOI: 10.1016/J.Mcn.2006.06.013  0.307
2006 Chen S, Hilcove S, Ding S. Exploring stem cell biology with small molecules. Molecular Biosystems. 2: 18-24. PMID 16880919 DOI: 10.1039/B512000B  0.859
2006 Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proceedings of the National Academy of Sciences of the United States of America. 103: 6907-12. PMID 16632596 DOI: 10.1073/Pnas.0602280103  0.84
2006 Adrián FJ, Ding Q, Sim T, Velentza A, Sloan C, Liu Y, Zhang G, Hur W, Ding S, Manley P, Mestan J, Fabbro D, Gray NS. Allosteric inhibitors of Bcr-abl-dependent cell proliferation Nature Chemical Biology. 2: 95-102. PMID 16415863 DOI: 10.1038/Nchembio760  0.476
2006 Warashina M, Min KH, Kuwabara T, Huynh A, Gage FH, Schultz PG, Ding S. A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. Angewandte Chemie (International Ed. in English). 45: 591-3. PMID 16323231 DOI: 10.1002/Anie.200503089  0.777
2006 Chen S, Ding S. GSK-3 and Stem Cells Glycogen Synthase Kinase 3 (Gsk-3) and Its Inhibitors: Drug Discovery and Development. 155-171. DOI: 10.1002/0470052171.ch8  0.463
2005 Zhao Y, Clark J, Ding S. Genomic studies in stem cell systems. Current Opinion in Molecular Therapeutics. 7: 543-50. PMID 16370377  0.734
2005 Ding S, Schultz PG. Small molecules and future regenerative medicine. Current Topics in Medicinal Chemistry. 5: 383-95. PMID 15892681 DOI: 10.2174/1568026053828402  0.734
2005 Liu J, Wu X, Mitchell B, Kintner C, Ding S, Schultz PG. A small-molecule agonist of the Wnt signaling pathway. Angewandte Chemie (International Ed. in English). 44: 1987-90. PMID 15724259 DOI: 10.1002/Anie.200462552  0.642
2005 Liu J, Bang AG, Kintner C, Orth AP, Chanda SK, Ding S, Schultz PG. Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis. Proceedings of the National Academy of Sciences of the United States of America. 102: 1927-32. PMID 15677333 DOI: 10.1073/Pnas.0409472102  0.598
2004 Zheng L, Ding S. Mammalian genome-wide loss-of-function screens using arrayed small interfering RNA expression libraries. Discovery Medicine. 4: 102-5. PMID 20705002  0.43
2004 Wu X, Walker J, Zhang J, Ding S, Schultz PG. Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Chemistry & Biology. 11: 1229-38. PMID 15380183 DOI: 10.1016/J.Chembiol.2004.06.010  0.681
2004 Ding S, Schultz PG. A role for chemistry in stem cell biology. Nature Biotechnology. 22: 833-40. PMID 15229546 DOI: 10.1038/Nbt987  0.74
2004 Wu X, Ding S, Ding Q, Gray NS, Schultz PG. Small molecules that induce cardiomyogenesis in embryonic stem cells. Journal of the American Chemical Society. 126: 1590-1. PMID 14871063 DOI: 10.1021/Ja038950I  0.774
2004 Chen S, Zhang Q, Wu X, Schultz PG, Ding S. Dedifferentiation of lineage-committed cells by a small molecule. Journal of the American Chemical Society. 126: 410-1. PMID 14719906 DOI: 10.1021/Ja037390K  0.851
2004 Wu TY, Hassig C, Wu Y, Ding S, Schultz PG. Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group. Bioorganic & Medicinal Chemistry Letters. 14: 449-53. PMID 14698179 DOI: 10.1016/J.Bmcl.2003.10.055  0.792
2004 Zheng L, Liu J, Batalov S, Zhou D, Orth A, Ding S, Schultz PG. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 135-40. PMID 14688408 DOI: 10.1073/Pnas.2136685100  0.679
2003 Wu TY, Schultz PG, Ding S. One-pot two-step microwave-assisted reaction in constructing 4,5-disubstituted pyrazolopyrimidines. Organic Letters. 5: 3587-90. PMID 14507179 DOI: 10.1021/Ol035226W  0.611
2003 Ding S, Wu TY, Brinker A, Peters EC, Hur W, Gray NS, Schultz PG. Synthetic small molecules that control stem cell fate. Proceedings of the National Academy of Sciences of the United States of America. 100: 7632-7. PMID 12794184 DOI: 10.1073/Pnas.0732087100  0.86
2002 Chapman E, Ding S, Schultz PG, Wong CH. A potent and highly selective sulfotransferase inhibitor. Journal of the American Chemical Society. 124: 14524-5. PMID 12465948 DOI: 10.1021/Ja021086U  0.536
2002 Wu X, Ding S, Ding Q, Gray NS, Schultz PG. A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells. Journal of the American Chemical Society. 124: 14520-1. PMID 12465946 DOI: 10.1021/Ja0283908  0.792
2002 Ding S, Gray NS, Ding Q, Wu X, Schultz PG. Resin-capture and release strategy toward combinatorial libraries of 2,6,9-substituted purines. Journal of Combinatorial Chemistry. 4: 183-6. PMID 11886295 DOI: 10.1021/Cc010080I  0.64
2002 Chang YT, Choi J, Ding S, Prieschl EE, Baumruker T, Lee JM, Chung SK, Schultz PG. The synthesis and biological characterization of a ceramide library. Journal of the American Chemical Society. 124: 1856-7. PMID 11866590 DOI: 10.1021/Ja017576O  0.688
2002 Ding S, Gray NS, Wu X, Ding Q, Schultz PG. A combinatorial scaffold approach toward kinase-directed heterocycle libraries. Journal of the American Chemical Society. 124: 1594-6. PMID 11853431 DOI: 10.1021/Ja0170302  0.676
2001 Ding S, Gray NS, Ding Q, Schultz PG. A concise and traceless linker strategy toward combinatorial libraries of 2,6,9-substituted purines. The Journal of Organic Chemistry. 66: 8273-6. PMID 11722241 DOI: 10.1021/Jo016010F  0.597
2001 Wu TY, Ding S, Gray NS, Schultz PG. Solid-phase synthesis of 2,3,5-trisubstituted indoles. Organic Letters. 3: 3827-30. PMID 11720546 DOI: 10.1021/Ol016525T  0.658
2001 Ding S, Gray NS, Ding Q, Schultz PG. Expanding the diversity of purine libraries Tetrahedron Letters. 42: 8751-8755. DOI: 10.1016/S0040-4039(01)01925-6  0.596
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