| Year |
Citation |
Score |
| 2022 |
Hurley MM, Coffin JD, Doetschman T, Valera C, Clarke K, Xiao L. FGF receptor inhibitor BGJ398 partially rescues osteoarthritis-like phenotype in older high molecular weight FGF2 transgenic mice via multiple mechanisms. Scientific Reports. 12: 15968. PMID 36153352 DOI: 10.1038/s41598-022-20269-6 |
0.313 |
|
| 2019 |
Romagnolo DF, Donovan MG, Doetschman TC, Selmin OI. -6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer. Nutrients. 11. PMID 30650553 DOI: 10.3390/Nu11010171 |
0.305 |
|
| 2018 |
Burt PM, Xiao L, Doetschman T, Hurley MM. Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection. Journal of Cellular Physiology. PMID 30144364 DOI: 10.1002/Jcp.27230 |
0.438 |
|
| 2015 |
Ardila DC, Tamimi E, Danford FL, Haskett DG, Kellar RS, Doetschman T, Vande Geest JP. TGFβ2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs. Biomaterials. 37: 164-73. PMID 25453947 DOI: 10.1016/J.Biomaterials.2014.10.021 |
0.302 |
|
| 2015 |
Selmin OI, Lyon AM, Fang C, Doetschman TC, Thompson PA, Martinez JD, Smith J, Lance PM, Romagnolo DF. Abstract 905: Influence of high fat diet and APC status on epigenetic regulation of FXR in colon cells Cancer Research. 75: 905-905. DOI: 10.1158/1538-7445.Am2015-905 |
0.329 |
|
| 2014 |
Homer-Bouthiette C, Doetschman T, Xiao L, Hurley MM. Knockout of nuclear high molecular weight FGF2 isoforms in mice modulates bone and phosphate homeostasis. The Journal of Biological Chemistry. 289: 36303-14. PMID 25389287 DOI: 10.1074/Jbc.M114.619569 |
0.365 |
|
| 2014 |
Nusayr E, Sadideen DT, Doetschman TC. Erratum to: FGF2 modulates cardiac remodeling in an isoform-and sex-specific manner(Physiol Rep, (2013), 1, 4, e00088, 10.1002/phy2.88) Physiological Reports. 2. PMID 24920121 DOI: 10.14814/Phy2.12024 |
0.757 |
|
| 2013 |
Nusayr E, Doetschman T. Cardiac development and physiology are modulated by FGF2 in an isoform- and sex-specific manner. Physiological Reports. 1. PMID 24244870 DOI: 10.1002/Phy2.87 |
0.777 |
|
| 2013 |
Nusayr E, Sadideen DT, Doetschman T. FGF2 modulates cardiac remodeling in an isoform- and sex-specific manner. Physiological Reports. 1. PMID 24244869 DOI: 10.1002/Phy2.88 |
0.779 |
|
| 2012 |
Doetschman T, Azhar M. Cardiac-Specific Inducible and Conditional Gene Targeting in Mice Circulation Research. 110: 1498-1512. PMID 22628574 DOI: 10.1161/Circresaha.112.265066 |
0.385 |
|
| 2012 |
Manning JR, Carpenter G, Porter DR, House SL, Pietras DA, Doetschman T, Schultz Jel J. Fibroblast growth factor-2-induced cardioprotection against myocardial infarction occurs via the interplay between nitric oxide, protein kinase signaling, and ATP-sensitive potassium channels. Growth Factors (Chur, Switzerland). 30: 124-39. PMID 22304432 DOI: 10.3109/08977194.2012.656759 |
0.342 |
|
| 2012 |
Doetschman T, Georgieva T, Li H, Reed TD, Grisham C, Friel J, Estabrook MA, Gard C, Sanford LP, Azhar M. Generation of mice with a conditional allele for the transforming growth factor beta3 gene. Genesis (New York, N.Y. : 2000). 50: 59-66. PMID 22223248 DOI: 10.1002/Dvg.20789 |
0.432 |
|
| 2012 |
Doetschman T, Barnett JV, Runyan RB, Camenisch TD, Heimark RL, Granzier HL, Conway SJ, Azhar M. Transforming growth factor beta signaling in adult cardiovascular diseases and repair. Cell and Tissue Research. 347: 203-23. PMID 21953136 DOI: 10.1007/S00441-011-1241-3 |
0.309 |
|
| 2011 |
Fei Y, Xiao L, Doetschman T, Coffin DJ, Hurley MM. Fibroblast growth factor 2 stimulation of osteoblast differentiation and bone formation is mediated by modulation of the Wnt signaling pathway. The Journal of Biological Chemistry. 286: 40575-83. PMID 21987573 DOI: 10.1074/Jbc.M111.274910 |
0.37 |
|
| 2011 |
Conway SJ, Doetschman T, Azhar M. The inter-relationship of periostin, TGF beta, and BMP in heart valve development and valvular heart diseases. Thescientificworldjournal. 11: 1509-24. PMID 21805020 DOI: 10.1100/Tsw.2011.132 |
0.359 |
|
| 2011 |
Azhar M, Brown K, Gard C, Chen H, Rajan S, Elliott DA, Stevens MV, Camenisch TD, Conway SJ, Doetschman T. Transforming growth factor Beta2 is required for valve remodeling during heart development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 2127-41. PMID 21780244 DOI: 10.1002/Dvdy.22702 |
0.383 |
|
| 2011 |
Doetschman T, Sholl A, Chen Hdr, Gard C, Hildeman DA, Bommireddy R. Divergent effects of calcineurin Aβ on regulatory and conventional T-cell homeostasis. Clinical Immunology. 138: 321-330. PMID 21256088 DOI: 10.1016/J.Clim.2010.12.020 |
0.34 |
|
| 2010 |
House SL, House BE, Glascock B, Kimball T, Nusayr E, Schultz JE, Doetschman T. Fibroblast Growth Factor 2 Mediates Isoproterenol-induced Cardiac Hypertrophy through Activation of the Extracellular Regulated Kinase. Molecular and Cellular Pharmacology. 2: 143-154. PMID 21274419 DOI: 10.4255/Mcpharmacol.10.20 |
0.787 |
|
| 2010 |
Xiao L, Sobue T, Esliger A, Kronenberg MS, Coffin JD, Doetschman T, Hurley MM. Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells. Bone. 47: 360-70. PMID 20510392 DOI: 10.1016/J.Bone.2010.05.021 |
0.39 |
|
| 2010 |
Liao S, Bodmer JR, Azhar M, Newman G, Coffin JD, Doetschman T, Schultz Jel J. The influence of FGF2 high molecular weight (HMW) isoforms in the development of cardiac ischemia-reperfusion injury. Journal of Molecular and Cellular Cardiology. 48: 1245-54. PMID 20116383 DOI: 10.1016/J.Yjmcc.2010.01.014 |
0.433 |
|
| 2010 |
Nakao S, Maruyama K, Zandi S, Melhorn MI, Taher M, Noda K, Nusayr E, Doetschman T, Hafezi-Moghadam A. Lymphangiogenesis and angiogenesis: concurrence and/or dependence? Studies in inbred mouse strains. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 504-13. PMID 19858096 DOI: 10.1096/Fj.09-134056 |
0.75 |
|
| 2009 |
Snider P, Standley KN, Wang J, Azhar M, Doetschman T, Conway SJ. Origin of cardiac fibroblasts and the role of periostin. Circulation Research. 105: 934-47. PMID 19893021 DOI: 10.1161/Circresaha.109.201400 |
0.425 |
|
| 2009 |
Bommireddy R, Bueno OF, Martin J, Ormsby I, Chen H, Gard C, Molkentin JD, Boivin GP, Babcock GF, Doetschman T. Calcineurin deficiency decreases inflammatory lesions in transforming growth factor beta1-deficient mice. Clinical and Experimental Immunology. 158: 317-24. PMID 19747209 DOI: 10.1111/J.1365-2249.2009.04015.X |
0.372 |
|
| 2009 |
Azhar M, Runyan RB, Gard C, Sanford LP, Miller ML, Andringa A, Pawlowski S, Rajan S, Doetschman T. Ligand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 431-42. PMID 19161227 DOI: 10.1002/Dvdy.21854 |
0.43 |
|
| 2009 |
Sabbieti MG, Agas D, Xiao L, Marchetti L, Coffin JD, Doetschman T, Hurley MM. Endogenous FGF-2 is critically important in PTH anabolic effects on bone. Journal of Cellular Physiology. 219: 143-51. PMID 19107841 DOI: 10.1002/Jcp.21661 |
0.411 |
|
| 2009 |
Azhar M, Yin M, Zhou M, Li H, Mustafa M, Nusayr E, Keenan JB, Chen H, Pawlosky S, Gard C, Grisham C, Sanford LP, Doetschman T. Gene targeted ablation of high molecular weight fibroblast growth factor-2. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 351-7. PMID 19105223 DOI: 10.1002/Dvdy.21835 |
0.783 |
|
| 2009 |
Xiao L, Liu P, Li X, Doetschman T, Coffin JD, Drissi H, Hurley MM. Exported 18-kDa isoform of fibroblast growth factor-2 is a critical determinant of bone mass in mice. The Journal of Biological Chemistry. 284: 3170-82. PMID 19056741 DOI: 10.1074/Jbc.M804900200 |
0.405 |
|
| 2009 |
Liao S, Bodmer J, Pietras D, Azhar M, Doetschman T, Schultz Jel J. Biological functions of the low and high molecular weight protein isoforms of fibroblast growth factor-2 in cardiovascular development and disease. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 249-64. PMID 18773489 DOI: 10.1002/Dvdy.21677 |
0.44 |
|
| 2008 |
Chen K, Ohkubo Y, Shin D, Doetschman T, Sanford LP, Li H, Vaccarino FM. Decrease in excitatory neurons, astrocytes and proliferating progenitors in the cerebral cortex of mice lacking exon 3 from the Fgf2 gene. Bmc Neuroscience. 9: 94. PMID 18826624 DOI: 10.1186/1471-2202-9-94 |
0.443 |
|
| 2008 |
Prasad V, Bodi I, Meyer JW, Wang Y, Ashraf M, Engle SJ, Doetschman T, Sisco K, Nieman ML, Miller ML, Lorenz JN, Shull GE. Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases. The Journal of Biological Chemistry. 283: 31303-14. PMID 18779325 DOI: 10.1074/Jbc.M803706200 |
0.375 |
|
| 2008 |
Bommireddy R, Babcock GF, Singh RR, Doetschman T. TGFβ1 deficiency does not affect the generation and maintenance of CD4+CD25+FOXP3+ putative Treg cells, but causes their numerical inadequacy and loss of regulatory function Clinical Immunology. 127: 206-213. PMID 18308639 DOI: 10.1016/J.Clim.2007.12.008 |
0.315 |
|
| 2008 |
Naganawa T, Xiao L, Coffin JD, Doetschman T, Sabbieti MG, Agas D, Hurley MM. Reduced expression and function of bone morphogenetic protein-2 in bones of Fgf2 null mice. Journal of Cellular Biochemistry. 103: 1975-88. PMID 17955502 DOI: 10.1002/Jcb.21589 |
0.402 |
|
| 2007 |
Makwana M, Jones LL, Cuthill D, Heuer H, Bohatschek M, Hristova M, Friedrichsen S, Ormsby I, Bueringer D, Koppius A, Bauer K, Doetschman T, Raivich G. Endogenous transforming growth factor beta 1 suppresses inflammation and promotes survival in adult CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11201-13. PMID 17942715 DOI: 10.1523/Jneurosci.2255-07.2007 |
0.319 |
|
| 2007 |
Kaiser S, Park YK, Franklin JL, Halberg RB, Yu M, Jessen WJ, Freudenberg J, Chen X, Haigis K, Jegga AG, Kong S, Sakthivel B, Xu H, Reichling T, Azhar M, ... ... Doetschman T, et al. Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biology. 8: R131. PMID 17615082 DOI: 10.1186/Gb-2007-8-7-R131 |
0.307 |
|
| 2007 |
Okunade GW, Miller ML, Azhar M, Andringa A, Sanford LP, Doetschman T, Prasad V, Shull GE. Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes. The Journal of Biological Chemistry. 282: 26517-27. PMID 17597066 DOI: 10.1074/Jbc.M703029200 |
0.334 |
|
| 2007 |
House SL, Melhorn SJ, Newman G, Doetschman T, Schultz Jel J. The protein kinase C pathway mediates cardioprotection induced by cardiac-specific overexpression of fibroblast growth factor-2. American Journal of Physiology. Heart and Circulatory Physiology. 293: H354-65. PMID 17337596 DOI: 10.1152/Ajpheart.00804.2006 |
0.375 |
|
| 2007 |
Gawenis LR, Bradford EM, Prasad V, Lorenz JN, Simpson JE, Clarke LL, Woo AL, Grisham C, Sanford LP, Doetschman T, Miller ML, Shull GE. Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter. The Journal of Biological Chemistry. 282: 9042-52. PMID 17192275 DOI: 10.1074/Jbc.M607041200 |
0.321 |
|
| 2007 |
Brown RL, Ormsby I, Doetschman TC, Greenhalgh DG. Wound healing in the transforming growth factor-beta-deficient mouse. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 3: 25-36. PMID 17168860 DOI: 10.1046/J.1524-475X.1995.30108.X |
0.329 |
|
| 2007 |
Liao S, Porter D, Scott A, Newman G, Doetschman T, Schultz Jel J. The cardioprotective effect of the low molecular weight isoform of fibroblast growth factor-2: the role of JNK signaling. Journal of Molecular and Cellular Cardiology. 42: 106-20. PMID 17150229 DOI: 10.1016/J.Yjmcc.2006.10.005 |
0.402 |
|
| 2007 |
Liao S, Newman G, Doetschman T, Schultz JEJ. Role of high molecular weight isoforms of fibroblast growth factor-2 (FGF-2) in cardiac ischemia–reperfusion injury (I/R) Journal of Molecular and Cellular Cardiology. 42: S198. DOI: 10.1016/J.Yjmcc.2007.03.601 |
0.374 |
|
| 2006 |
Fontaine V, Filipe C, Werner N, Gourdy P, Billon A, Garmy-Susini B, Brouchet L, Bayard F, Prats H, Doetschman TC, Nickenig G, Arnal JF. Essential Role of Bone Marrow Fibroblast Growth Factor-2 in the Effect of Estradiol on Reendothelialization and Endothelial Progenitor Cell Mobilization American Journal of Pathology. 169: 1855-1862. PMID 17071606 DOI: 10.2353/Ajpath.2006.060260 |
0.431 |
|
| 2006 |
Bommireddy R, Pathak LJ, Martin J, Ormsby I, Engle SJ, Boivin GP, Babcock GF, Eriksson AU, Singh RR, Doetschman T. Self-antigen recognition by TGF beta1-deficient T cells causes their activation and systemic inflammation. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 1008-19. PMID 16865088 DOI: 10.1038/Labinvest.3700460 |
0.321 |
|
| 2006 |
Hurley MM, Okada Y, Xiao L, Tanaka Y, Ito M, Okimoto N, Nakamura T, Rosen CJ, Doetschman T, Coffin JD. Impaired bone anabolic response to parathyroid hormone in Fgf2-/- and Fgf2+/- mice. Biochemical and Biophysical Research Communications. 341: 989-94. PMID 16455048 DOI: 10.1016/J.Bbrc.2006.01.044 |
0.439 |
|
| 2005 |
House SL, Branch K, Newman G, Doetschman T, Schultz Jel J. Cardioprotection induced by cardiac-specific overexpression of fibroblast growth factor-2 is mediated by the MAPK cascade. American Journal of Physiology. Heart and Circulatory Physiology. 289: H2167-75. PMID 16040717 DOI: 10.1152/Ajpheart.00392.2005 |
0.406 |
|
| 2005 |
Gawenis LR, Greeb JM, Prasad V, Grisham C, Sanford LP, Doetschman T, Andringa A, Miller ML, Shull GE. Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger. The Journal of Biological Chemistry. 280: 12781-9. PMID 15684419 DOI: 10.1074/Jbc.M414118200 |
0.374 |
|
| 2004 |
Molin DG, Poelmann RE, DeRuiter MC, Azhar M, Doetschman T, Gittenberger-de Groot AC. Transforming growth factor beta-SMAD2 signaling regulates aortic arch innervation and development. Circulation Research. 95: 1109-17. PMID 15528466 DOI: 10.1161/01.Res.0000150047.16909.Ab |
0.322 |
|
| 2004 |
Poelmann RE, Jongbloed MR, Molin DG, Fekkes ML, Wang Z, Fishman GI, Doetschman T, Azhar M, Gittenberger-de Groot AC. The neural crest is contiguous with the cardiac conduction system in the mouse embryo: a role in induction? Anatomy and Embryology. 208: 389-93. PMID 15248063 DOI: 10.1007/S00429-004-0401-6 |
0.426 |
|
| 2004 |
Okunade GW, Miller ML, Pyne GJ, Sutliff RL, O'Connor KT, Neumann JC, Andringa A, Miller DA, Prasad V, Doetschman T, Paul RJ, Shull GE. Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4. The Journal of Biological Chemistry. 279: 33742-50. PMID 15178683 DOI: 10.1074/Jbc.M404628200 |
0.337 |
|
| 2004 |
Gawenis LR, Ledoussal C, Judd LM, Prasad V, Alper SL, Stuart-Tilley A, Woo AL, Grisham C, Sanford LP, Doetschman T, Miller ML, Shull GE. Mice with a targeted disruption of the AE2 Cl-/HCO3- exchanger are achlorhydric. The Journal of Biological Chemistry. 279: 30531-9. PMID 15123620 DOI: 10.1074/Jbc.M403779200 |
0.36 |
|
| 2004 |
Garmy-Susini B, Delmas E, Gourdy P, Zhou M, Bossard C, Bugler B, Bayard F, Krust A, Prats AC, Doetschman T, Prats H, Arnal JF. Role of Fibroblast Growth Factor-2 Isoforms in the Effect of Estradiol on Endothelial Cell Migration and Proliferation Circulation Research. 94: 1301-1309. PMID 15073041 DOI: 10.1161/01.Res.0000127719.13255.81 |
0.461 |
|
| 2004 |
Azhar M, Schultz Jel J, Grupp I, Dorn GW, Meneton P, Molin DG, Gittenberger-de Groot AC, Doetschman T. Transforming growth factor beta in cardiovascular development and function. Cytokine & Growth Factor Reviews. 14: 391-407. PMID 12948523 DOI: 10.1016/S1359-6101(03)00044-3 |
0.376 |
|
| 2004 |
Garmy-Susini B, Delmas E, Gourdy P, Zhou M, Brouchet L, Bayard F, Prats AC, Doetschman T, Prats H, Arnal JF. HIGH MW FGF2, BUT NOT LOW MW FGF2 NOR VEGF, MEDIATES THE EFFECT OF ESTRADIOL ON REENDOTHELIALIZATION Journal of Hypertension. 22: S189. DOI: 10.1097/00004872-200406002-00655 |
0.34 |
|
| 2003 |
House SL, Bolte C, Zhou M, Doetschman T, Klevitsky R, Newman G, Schultz Jel J. Cardiac-specific overexpression of fibroblast growth factor-2 protects against myocardial dysfunction and infarction in a murine model of low-flow ischemia. Circulation. 108: 3140-8. PMID 14656920 DOI: 10.1161/01.Cir.0000105723.91637.1C |
0.468 |
|
| 2003 |
Skelton MR, Ponniah S, Wang DZ, Doetschman T, Vorhees CV, Pallen CJ. Protein tyrosine phosphatase alpha (PTP alpha) knockout mice show deficits in Morris water maze learning, decreased locomotor activity, and decreases in anxiety. Brain Research. 984: 1-10. PMID 12932834 DOI: 10.1016/S0006-8993(03)02839-7 |
0.348 |
|
| 2003 |
Bommireddy R, Saxena V, Ormsby I, Yin M, Boivin GP, Babcock GF, Singh RR, Doetschman T. TGF-beta 1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 170: 4612-22. PMID 12707339 DOI: 10.4049/Jimmunol.170.9.4612 |
0.325 |
|
| 2003 |
Okada Y, Montero A, Zhang X, Sobue T, Lorenzo J, Doetschman T, Coffin JD, Hurley MM. Impaired osteoclast formation in bone marrow cultures of Fgf2 null mice in response to parathyroid hormone. The Journal of Biological Chemistry. 278: 21258-66. PMID 12665515 DOI: 10.1074/Jbc.M302113200 |
0.411 |
|
| 2003 |
Bommireddy R, Ormsby I, Yin M, Boivin GP, Babcock GF, Doetschman T. TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes. Journal of Immunology (Baltimore, Md. : 1950). 170: 3645-52. PMID 12646629 DOI: 10.4049/Jimmunol.170.7.3645 |
0.3 |
|
| 2002 |
Sullivan CJ, Doetschman T, Hoying JB. Targeted disruption of the Fgf2 gene does not affect vascular growth in the mouse ischemic hindlimb. Journal of Applied Physiology (Bethesda, Md. : 1985). 93: 2009-17. PMID 12391121 DOI: 10.1152/Japplphysiol.00451.2002 |
0.443 |
|
| 2002 |
Pietri L, Bloch-Faure M, Belair MF, Sanford LP, Doetschman T, Ménard J, Bruneval P, Meneton P. Altered renin synthesis and secretion in the kidneys of heterozygous mice with a null mutation in the TGF-beta(2) gene. Experimental Nephrology. 10: 374-82. PMID 12381922 DOI: 10.1159/000065302 |
0.331 |
|
| 2002 |
Paradis H, Liu CY, Saika S, Azhar M, Doetschman T, Good WV, Nayak R, Laver N, Kao CW, Kao WW, Gendron RL. Tubedown-1 in remodeling of the developing vitreal vasculature in vivo and regulation of capillary outgrowth in vitro. Developmental Biology. 249: 140-55. PMID 12217325 DOI: 10.1006/Dbio.2002.0757 |
0.357 |
|
| 2002 |
Lorenz JN, Baird NR, Judd LM, Noonan WT, Andringa A, Doetschman T, Manning PA, Liu LH, Miller ML, Shull GE. Impaired renal NaCl absorption in mice lacking the ROMK potassium channel, a model for type II Bartter's syndrome. The Journal of Biological Chemistry. 277: 37871-80. PMID 12122007 DOI: 10.1074/Jbc.M205627200 |
0.304 |
|
| 2002 |
Shao C, Yin M, Deng L, Stambrook PJ, Doetschman T, Tischfield JA. Loss of heterozygosity and point mutation at Aprt locus in T cells and fibroblasts of Pms2-/- mice. Oncogene. 21: 2840-5. PMID 11973643 DOI: 10.1038/Sj.Onc.1205358 |
0.364 |
|
| 2002 |
Schultz JEJ, Witt SA, Glascock BJ, Nieman ML, Reiser PJ, Nix SL, Kimball TR, Doetschman T. TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II Journal of Clinical Investigation. 109: 787-796. PMID 11901187 DOI: 10.1172/Jci14190 |
0.354 |
|
| 2001 |
Bommireddy R, Ormsby I, Yin M, Doetschman TC. Role of Transforming Growth Factor 1 in Lymphocyte Development and Death. Thescientificworldjournal. 1: 146. PMID 30147623 DOI: 10.1100/Tsw.2001.243 |
0.348 |
|
| 2001 |
Thomas RM, Belsito DV, Huang C, Chen Lz LZ, Ormsby I, Simmons WJ, Cowin P, Shaw J, Doetschman T, Thorbecke GJ. Appearance of Langerhans cells in the epidermis of Tgfb1(-/-) SCID mice: paracrine and autocrine effects of transforming growth factor-beta 1 and -beta 2(1). The Journal of Investigative Dermatology. 117: 1574-80. PMID 11886525 DOI: 10.1046/J.0022-202X.2001.01550.X |
0.38 |
|
| 2001 |
Bartram U, Molin DGM, Wisse LJ, Mohamad A, Sanford LP, Doetschman T, Speer CP, Poelmann RE, Gittenberger-de Groot AC. Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-β2-knockout mice Circulation. 103: 2745-2752. PMID 11390347 DOI: 10.1161/01.Cir.103.22.2745 |
0.393 |
|
| 2001 |
Krane CM, Melvin JE, Nguyen HV, Richardson L, Towne JE, Doetschman T, Menon AG. Salivary acinar cells from aquaporin 5-deficient mice have decreased membrane water permeability and altered cell volume regulation. The Journal of Biological Chemistry. 276: 23413-20. PMID 11290736 DOI: 10.1074/Jbc.M008760200 |
0.346 |
|
| 2001 |
Meneton P, Bloch-Faure M, Hagege AA, Ruetten H, Huang W, Bergaya S, Ceiler D, Gehring D, Martins I, Salmon G, Boulanger CM, Nussberger J, Crozatier B, Gasc JM, Heudes D, ... ... Doetschman T, et al. Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 98: 2634-2639. PMID 11226291 DOI: 10.1073/Pnas.051619598 |
0.396 |
|
| 2000 |
Crowe MJ, Doetschman T, Greenhalgh DG. Delayed wound healing in immunodeficient TGF-beta 1 knockout mice. The Journal of Investigative Dermatology. 115: 3-11. PMID 10886500 DOI: 10.1046/J.1523-1747.2000.00010.X |
0.365 |
|
| 2000 |
Montero A, Okada Y, Tomita M, Ito M, Tsurukami H, Nakamura T, Doetschman T, Coffin JD, Hurley MM. Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation. The Journal of Clinical Investigation. 105: 1085-93. PMID 10772653 DOI: 10.1172/Jci8641 |
0.332 |
|
| 2000 |
Spicer Z, Miller ML, Andringa A, Riddle TM, Duffy JJ, Doetschman T, Shull GE. Stomachs of mice lacking the gastric H,K-ATPase alpha -subunit have achlorhydria, abnormal parietal cells, and ciliated metaplasia. The Journal of Biological Chemistry. 275: 21555-65. PMID 10764766 DOI: 10.1074/Jbc.M001558200 |
0.336 |
|
| 1999 |
Abel ED, Kaulbach HC, Tian R, Hopkins JC, Duffy J, Doetschman T, Minnemann T, Boers ME, Hadro E, Oberste-Berghaus C, Quist W, Lowell BB, Ingwall JS, Kahn BB. Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. The Journal of Clinical Investigation. 104: 1703-14. PMID 10606624 DOI: 10.1172/Jci7605 |
0.412 |
|
| 1999 |
Schultz JE, Witt SA, Nieman ML, Reiser PJ, Engle SJ, Zhou M, Pawlowski SA, Lorenz JN, Kimball TR, Doetschman T. Fibroblast growth factor-2 mediates pressure-induced hypertrophic response. The Journal of Clinical Investigation. 104: 709-19. PMID 10491406 DOI: 10.1172/Jci7315 |
0.517 |
|
| 1999 |
Flagella M, Clarke LL, Miller ML, Erway LC, Giannella RA, Andringa A, Gawenis LR, Kramer J, Duffy JJ, Doetschman T, Lorenz JN, Yamoah EN, Cardell EL, Shull GE. Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf. The Journal of Biological Chemistry. 274: 26946-55. PMID 10480906 DOI: 10.1074/Jbc.274.38.26946 |
0.342 |
|
| 1999 |
Foitzik K, Paus R, Doetschman T, Dotto GP. The TGF-β2 Isoform Is Both a Required and Sufficient Inducer of Murine Hair Follicle Morphogenesis Developmental Biology. 212: 278-289. PMID 10433821 DOI: 10.1006/Dbio.1999.9325 |
0.338 |
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| 1999 |
Vaccarino FM, Schwartz ML, Raballo R, Nilsen J, Rhee J, Zhou M, Doetschman T, Coffin JD, Wyland JJ, Hung YT. Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis. Nature Neuroscience. 2: 246-53. PMID 10195217 DOI: 10.1038/6350 |
0.392 |
|
| 1999 |
Li J, Foitzik K, Calautti E, Baden H, Doetschman T, Dotto GP. TGF-beta3, but not TGF-beta1, protects keratinocytes against 12-O-tetradecanoylphorbol-13-acetate-induced cell death in vitro and in vivo. Journal of Biological Chemistry. 274: 4213-4219. PMID 9933619 DOI: 10.1074/Jbc.274.7.4213 |
0.31 |
|
| 1999 |
Periasamy M, Reed TD, Liu LH, Ji Y, Loukianov E, Paul RJ, Nieman ML, Riddle T, Duffy JJ, Doetschman T, Lorenz JN, Shull GE. Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 (SERCA2) gene. The Journal of Biological Chemistry. 274: 2556-62. PMID 9891028 DOI: 10.1074/Jbc.274.4.2556 |
0.37 |
|
| 1998 |
Paradies NE, Sanford LP, Doetschman T, Friedman RA. Developmental expression of the TGFβs in the mouse cochlea Mechanisms of Development. 79: 165-168. PMID 10349630 DOI: 10.1016/S0925-4773(98)00184-1 |
0.355 |
|
| 1998 |
Schultheis PJ, Lorenz JN, Meneton P, Nieman ML, Riddle TM, Flagella M, Duffy JJ, Doetschman T, Miller ML, Shull GE. Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule. The Journal of Biological Chemistry. 273: 29150-5. PMID 9786924 DOI: 10.1074/Jbc.273.44.29150 |
0.361 |
|
| 1998 |
Kozel PJ, Friedman RA, Erway LC, Yamoah EN, Liu LH, Riddle T, Duffy JJ, Doetschman T, Miller ML, Cardell EL, Shull GE. Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2. The Journal of Biological Chemistry. 273: 18693-6. PMID 9668038 DOI: 10.1074/Jbc.273.30.18693 |
0.391 |
|
| 1998 |
Schultheis PJ, Clarke LL, Meneton P, Miller ML, Soleimani M, Gawenis LR, Riddle TM, Duffy JJ, Doetschman T, Wang T, Giebisch G, Aronson PS, Lorenz JN, Shull GE. Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Nature Genetics. 19: 282-5. PMID 9662405 DOI: 10.1038/969 |
0.332 |
|
| 1998 |
Schultheis PJ, Clarke LL, Meneton P, Harline M, Boivin GP, Stemmermann G, Duffy JJ, Doetschman T, Miller ML, Shull GE. Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion. The Journal of Clinical Investigation. 101: 1243-53. PMID 9502765 DOI: 10.1172/Jci1249 |
0.331 |
|
| 1998 |
Zhou M, Sutliff RL, Paul RJ, Lorenz JN, Hoying JB, Haudenschild CC, Yin M, Coffin JD, Kong L, Kranias EG, Luo W, Boivin GP, Duffy JJ, Pawlowski SA, Doetschman T. Fibroblast growth factor 2 control of vascular tone. Nature Medicine. 4: 201-7. PMID 9461194 DOI: 10.1038/Nm0298-201 |
0.346 |
|
| 1998 |
Meneton P, Schultheis PJ, Greeb J, Nieman ML, Liu LH, Clarke LL, Duffy JJ, Doetschman T, Lorenz JN, Shull GE. Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice. The Journal of Clinical Investigation. 101: 536-42. PMID 9449685 DOI: 10.1172/Jci1720 |
0.312 |
|
| 1997 |
Lightfoot PS, Swisher R, Coffin JD, Doetschman TC, German RZ. Ontogenetic limb bone scaling in basic fibroblast growth factor (FGF-2) transgenic mice. Growth, Development, and Aging : Gda. 61: 127-39. PMID 9546104 |
0.302 |
|
| 1997 |
Liu LH, Paul RJ, Sutliff RL, Miller ML, Lorenz JN, Pun RY, Duffy JJ, Doetschman T, Kimura Y, MacLennan DH, Hoying JB, Shull GE. Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3. The Journal of Biological Chemistry. 272: 30538-45. PMID 9374548 DOI: 10.1074/Jbc.272.48.30538 |
0.308 |
|
| 1997 |
Boivin GP, Ormsby I, Jones-Carson J, O'Toole BA, Doetschman T. Germ-free and barrier-raised TGFβ1-deficient mice have similar inflammatory lesions Transgenic Research. 6: 197-202. PMID 9167267 DOI: 10.1023/A:1018490007745 |
0.395 |
|
| 1997 |
Davis MG, Zhou M, Ali S, Coffin JD, Doetschman T, Dorn GW. Intracrine and autocrine effects of basic fibroblast growth factor in vascular smooth muscle cells. Journal of Molecular and Cellular Cardiology. 29: 1061-72. PMID 9160859 DOI: 10.1006/Jmcc.1997.0383 |
0.361 |
|
| 1997 |
Kumar A, Crawford K, Close L, Madison M, Lorenz J, Doetschman T, Pawlowski S, Duffy J, Neumann J, Robbins J, Boivin GP, O’Toole BA, Lessard JL. Rescue of cardiac α-actin-deficient mice by enteric smooth muscle γ-actin Proceedings of the National Academy of Sciences of the United States of America. 94: 4406-4411. PMID 9114002 DOI: 10.1073/Pnas.94.9.4406 |
0.368 |
|
| 1996 |
Jones WK, Grupp IL, Doetschman T, Grupp G, Osinska H, Hewett TE, Boivin G, Gulick J, Ng WA, Robbins J. Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart. The Journal of Clinical Investigation. 98: 1906-17. PMID 8878443 DOI: 10.1172/Jci118992 |
0.339 |
|
| 1996 |
Fontaine RN, Gossett RE, Schroeder F, O'Toole BA, Doetschman T, Kier AB. Liver and intestinal fatty acid binding proteins in control and TGFβ1 gene targeted deficient mice Molecular and Cellular Biochemistry. 159: 149-153. PMID 8858565 DOI: 10.1007/Bf00420917 |
0.34 |
|
| 1996 |
Luo W, Wolska BM, Grupp IL, Harrer JM, Haghighi K, Ferguson DG, Slack JP, Grupp G, Doetschman T, Solaro RJ, Kranias EG. Phospholamban gene dosage effects in the mammalian heart. Circulation Research. 78: 839-47. PMID 8620604 DOI: 10.1161/01.Res.78.5.839 |
0.423 |
|
| 1996 |
Kallapur SG, Ormsby I, Doetschman TC. STRAIN DEPENDENCY OF TRANSFORMING GROWTH FACTOR-BETA 1 (TGF-betal) REQUIREMENT FOR PREIMPLANTATION MOUSE DEVELOPMENT. |[dagger]| 352 Pediatric Research. 39: 61-61. DOI: 10.1203/00006450-199604001-00372 |
0.319 |
|
| 1995 |
Diebold RJ, Eis MJ, Yin M, Ormsby I, Boivin GP, Darrow BJ, Saffitz JE, Doetschman T. Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated. Proceedings of the National Academy of Sciences of the United States of America. 92: 12215-9. PMID 8618872 DOI: 10.1073/Pnas.92.26.12215 |
0.375 |
|
| 1995 |
Proetzel G, Pawlowski SA, Wiles MV, Yin M, Boivin GP, Howles PN, Ding J, Ferguson MW, Doetschman T. Transforming growth factor-beta 3 is required for secondary palate fusion. Nature Genetics. 11: 409-14. PMID 7493021 DOI: 10.1038/Ng1295-409 |
0.347 |
|
| 1994 |
Luo W, Grupp IL, Harrer J, Ponniah S, Grupp G, Duffy JJ, Doetschman T, Kranias EG. Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. Circulation Research. 75: 401-9. PMID 8062415 DOI: 10.1161/01.Res.75.3.401 |
0.433 |
|
| 1993 |
Shaw-white JR, Denko N, Albers L, Doetschman TC, Stringer JR. Expression of the lacZ gene targeted to the HPRT locus in embryonic stem cells and their derivatives Transgenic Research. 2: 1-13. PMID 8513334 DOI: 10.1007/Bf01977675 |
0.35 |
|
| 1993 |
Doetschman T, Shull M, Kier A, Coffin JD. Embryonic stem cell model systems for vascular morphogenesis and cardiac disorders. Hypertension. 22: 618-29. PMID 8406668 DOI: 10.1161/01.Hyp.22.4.618 |
0.338 |
|
| 1993 |
Muthuchamy M, Pajak L, Howles P, Doetschman T, Wieczorek DF. Developmental analysis of tropomyosin gene expression in embryonic stem cells and mouse embryos Molecular and Cellular Biology. 13: 3311-3323. PMID 7684495 DOI: 10.1128/Mcb.13.6.3311 |
0.373 |
|
| 1992 |
Robbins J, Doetschman TC, Jones WK, Sánchez A. Embryonic stem cells as a model for cardiogenesis. Trends in Cardiovascular Medicine. 2: 44-50. PMID 21239273 DOI: 10.1016/1050-1738(92)90003-B |
0.315 |
|
| 1992 |
Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D, Annunziata N, Doetschman T. Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease [14] Nature. 359: 693-699. PMID 1436033 DOI: 10.1038/359693A0 |
0.336 |
|
| 1992 |
Ganim JR, Luo W, Ponniah S, Grupp I, Kim HW, Ferguson DG, Kadambi V, Neumann JC, Doetschman T, Kranias EG. Mouse phospholamban gene expression during development in vivo and in vitro. Circulation Research. 71: 1021-30. PMID 1394867 DOI: 10.1161/01.Res.71.5.1021 |
0.415 |
|
| 1988 |
Doetschman T, Williams P, Maeda N. Establishment of hamster blastocyst-derived embryonic stem (ES) cells. Developmental Biology. 127: 224-7. PMID 3360212 DOI: 10.1016/0012-1606(88)90204-7 |
0.326 |
|
| 1988 |
Doetschman T, Maeda N, Smithies O. Targeted mutation of the Hprt gene in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 8583-7. PMID 3186749 DOI: 10.1073/Pnas.85.22.8583 |
0.487 |
|
| 1987 |
Doetschman T, Gregg RG, Maeda N, Hooper ML, Melton DW, Thompson S, Smithies O. Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature. 330: 576-8. PMID 3683574 DOI: 10.1038/330576A0 |
0.508 |
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