Joseph L. Kissil - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Oncology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Shepard A, Kissil JL. The use of non-traditional models in the study of cancer resistance-the case of the naked mole rat. Oncogene. 39: 5083-5097. PMID 32535616 DOI: 10.1038/S41388-020-1355-8  0.302
2020 Hoxha S, Shepard A, Troutman S, Diao H, Doherty JR, Janiszewska M, Witwicki RM, Pipkin ME, Ja WW, Kareta MS, Kissil JL. YAP-mediated recruitment of YY1 and EZH2 represses transcription of key cell cycle regulators. Cancer Research. PMID 32409309 DOI: 10.1158/0008-5472.Can-19-2415  0.399
2019 Cui Y, Groth S, Troutman S, Carlstedt A, Sperka T, Riecken LB, Kissil JL, Jin H, Morrison H. The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling. Oncogene. PMID 31312020 DOI: 10.1038/S41388-019-0883-6  0.337
2019 Cui Y, Groth S, Troutman S, Carlstedt A, Sperka T, Riecken LB, Kissil JL, Jin H, Morrison H. The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling. Oncogene. PMID 31312020 DOI: 10.1038/S41388-019-0883-6  0.337
2018 Kota S, Hou S, Guerrant W, Madoux F, Troutman S, Fernandez-Vega V, Alekseeva N, Madala N, Scampavia L, Kissil J, Spicer TP. A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype. Oncogene. PMID 29743592 DOI: 10.1038/S41388-018-0257-5  0.427
2018 Chinthalapudi K, Mandati V, Zheng J, Sharff AJ, Bricogne G, Griffin PR, Kissil J, Izard T. Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2. Nature Communications. 9: 1338. PMID 29626191 DOI: 10.1038/S41467-018-03648-4  0.393
2018 Lyons J, Brubaker DK, Ghazi PC, Baldwin KR, Edwards A, Boukhali M, Strasser SD, Suarez-Lopez L, Lin YJ, Yajnik V, Kissil JL, Haas W, Lauffenburger DA, Haigis KM. Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis. Science Signaling. 11. PMID 29487189 DOI: 10.1126/Scisignal.Aan3580  0.347
2018 Carper MB, Troutman S, Byrd KM, Wagner B, Henry EC, Montgomery SA, Williams SE, Kissil JL, Amelio AL. Abstract 1032: Novel mouse models of high-risk HPV-related oral cancers Cancer Research. 78: 1032-1032. DOI: 10.1158/1538-7445.Am2018-1032  0.329
2017 Moleirinho S, Hoxha S, Mandati V, Curtale G, Troutman S, Ehmer U, Kissil JL. Regulation of localization and function of the transcriptional co-activator YAP by angiomotin. Elife. 6. PMID 28464980 DOI: 10.7554/Elife.23966  0.406
2017 Blakeley JO, Bakker A, Barker A, Clapp W, Ferner R, Fisher MJ, Giovannini M, Gutmann DH, Karajannis MA, Kissil JL, Legius E, Lloyd AC, Packer RJ, Ramesh V, Riccardi VM, et al. The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis. American Journal of Medical Genetics. Part A. PMID 28436162 DOI: 10.1002/Ajmg.A.38239  0.353
2016 Troutman S, Moleirinho S, Kota S, Nettles K, Fallahi M, Johnson GL, Kissil JL. Crizotinib inhibits NF2-associated schwannoma through inhibition of focal adhesion kinase 1. Oncotarget. PMID 27363027 DOI: 10.18632/Oncotarget.10248  0.42
2016 Guerrant W, Kota S, Troutman S, Mandati V, Fallahi M, Stemmer-Rachamimov A, Kissil JL. YAP mediates tumorigenesis in neurofibromatosis type 2 by promoting cell survival and proliferation through a COX2-EGFR signaling axis. Cancer Research. PMID 27216189 DOI: 10.1158/0008-5472.Can-15-1144  0.458
2014 Moleirinho S, Guerrant W, Kissil JL. The Angiomotins--from discovery to function. Febs Letters. 588: 2693-703. PMID 24548561 DOI: 10.1016/J.Febslet.2014.02.006  0.389
2014 Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, ... ... Kissil J, et al. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. American Journal of Medical Genetics. Part A. 164: 563-78. PMID 24443315 DOI: 10.1002/Ajmg.A.36312  0.338
2013 Yi C, Shen Z, Stemmer-Rachamimov A, Dawany N, Troutman S, Showe LC, Liu Q, Shimono A, Sudol M, Holmgren L, Stanger BZ, Kissil JL. The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis. Science Signaling. 6: ra77. PMID 24003254 DOI: 10.1126/Scisignal.2004060  0.419
2013 Licciulli S, Maksimoska J, Zhou C, Troutman S, Kota S, Liu Q, Duron S, Campbell D, Chernoff J, Field J, Marmorstein R, Kissil JL. FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas. The Journal of Biological Chemistry. 288: 29105-14. PMID 23960073 DOI: 10.1074/Jbc.M113.510933  0.457
2013 Licciulli S, Avila JL, Hanlon L, Troutman S, Cesaroni M, Kota S, Keith B, Simon MC, Puré E, Radtke F, Capobianco AJ, Kissil JL. Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53. Cancer Research. 73: 5974-84. PMID 23943799 DOI: 10.1158/0008-5472.Can-13-1384  0.617
2013 Avila JL, Kissil JL. Notch signaling in pancreatic cancer: oncogene or tumor suppressor? Trends in Molecular Medicine. 19: 320-7. PMID 23545339 DOI: 10.1016/J.Molmed.2013.03.003  0.6
2013 Vaira V, Faversani A, Martin NM, Garlick DS, Ferrero S, Nosotti M, Kissil JL, Bosari S, Altieri DC. Regulation of lung cancer metastasis by Klf4-Numb-like signaling. Cancer Research. 73: 2695-705. PMID 23440423 DOI: 10.1158/0008-5472.Can-12-4232  0.429
2013 Zhou C, Licciulli S, Avila JL, Cho M, Troutman S, Jiang P, Kossenkov AV, Showe LC, Liu Q, Vachani A, Albelda SM, Kissil JL. The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Oncogene. 32: 903-9. PMID 22430205 DOI: 10.1038/Onc.2012.99  0.643
2012 Avila JL, Troutman S, Durham A, Kissil JL. Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinoma. Plos One. 7: e52133. PMID 23284900 DOI: 10.1371/Journal.Pone.0052133  0.611
2012 Coleman N, Kissil J. Recent advances in the development of p21-activated kinase inhibitors. Cellular Logistics. 2: 132-135. PMID 23162744 DOI: 10.4161/Cl.21667  0.335
2012 Caino MC, Lopez-Haber C, Kissil JL, Kazanietz MG. Non-small cell lung carcinoma cell motility, rac activation and metastatic dissemination are mediated by protein kinase C epsilon. Plos One. 7: e31714. PMID 22384062 DOI: 10.1371/Journal.Pone.0031714  0.381
2011 Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL. A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell. 19: 527-40. PMID 21481793 DOI: 10.1016/J.Ccr.2011.02.017  0.654
2011 Jung Y, Kissil JL, McCarty JH. β8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 271-7. PMID 21181944 DOI: 10.1002/Dvdy.22513  0.311
2010 Licciulli S, Kissil JL. WT1: a weak spot in KRAS-induced transformation. The Journal of Clinical Investigation. 120: 3804-7. PMID 20972324 DOI: 10.1172/Jci44901  0.461
2010 Yi C, Kissil JL. Merlin in organ size control and tumorigenesis: Hippo versus EGFR? Genes & Development. 24: 1673-9. PMID 20713513 DOI: 10.1101/Gad.1964810  0.389
2010 Mazumdar J, Hickey MM, Pant DK, Durham AC, Sweet-Cordero A, Vachani A, Jacks T, Chodosh LA, Kissil JL, Simon MC, Keith B. HIF-2alpha deletion promotes Kras-driven lung tumor development. Proceedings of the National Academy of Sciences of the United States of America. 107: 14182-7. PMID 20660313 DOI: 10.1073/Pnas.1001296107  0.348
2010 Hanlon L, Avila JL, Demarest RM, Troutman S, Allen M, Ratti F, Rustgi AK, Stanger BZ, Radtke F, Adsay V, Long F, Capobianco AJ, Kissil JL. Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma. Cancer Research. 70: 4280-6. PMID 20484026 DOI: 10.1158/0008-5472.Can-09-4645  0.634
2010 Yi C, Maksimoska J, Marmorstein R, Kissil JL. Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer. Biochemical Pharmacology. 80: 683-9. PMID 20302846 DOI: 10.1016/J.Bcp.2010.03.012  0.349
2010 Yi C, Kissil J. Abstract 1128: The tumor suppressive function of Merlin/Nf2 is mediated by a novel tight junction-associated protein complex Cancer Research. 70: 1128-1128. DOI: 10.1158/1538-7445.Am10-1128  0.496
2009 Santos AM, Jung J, Aziz N, Kissil JL, Puré E. Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. The Journal of Clinical Investigation. 119: 3613-25. PMID 19920354 DOI: 10.1172/Jci38988  0.452
2008 Yi C, Wilker EW, Yaffe MB, Stemmer-Rachamimov A, Kissil JL. Validation of the p21-activated kinases as targets for inhibition in neurofibromatosis type 2 Cancer Research. 68: 7932-7937. PMID 18829550 DOI: 10.1158/0008-5472.Can-08-0866  0.463
2008 Stedman W, Kang H, Lin S, Kissil JL, Bartolomei MS, Lieberman PM. Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. The Embo Journal. 27: 654-66. PMID 18219272 DOI: 10.1038/Emboj.2008.1  0.331
2007 Kissil JL, Walmsley MJ, Hanlon L, Haigis KM, Bender Kim CF, Sweet-Cordero A, Eckman MS, Tuveson DA, Capobianco AJ, Tybulewicz VL, Jacks T. Requirement for Rac1 in a K-ras induced lung cancer in the mouse. Cancer Research. 67: 8089-94. PMID 17804720 DOI: 10.1158/0008-5472.Can-07-2300  0.425
2007 Wong SY, Haack H, Kissil JL, Barry M, Bronson RT, Shen SS, Whittaker CA, Crowley D, Hynes RO. Protein 4.1B suppresses prostate cancer progression and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12784-9. PMID 17640904 DOI: 10.1073/Pnas.0705499104  0.377
2006 Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, Jacks T. Mouse models of human non-small-cell lung cancer: raising the bar. Cold Spring Harbor Symposia On Quantitative Biology. 70: 241-50. PMID 16869760 DOI: 10.1101/Sqb.2005.70.037  0.36
2005 Yi C, McCarty JH, Troutman SA, Eckman MS, Bronson RT, Kissil JL. Loss of the putative tumor suppressor band 4.1B/Dal1 gene is dispensable for normal development and does not predispose to cancer. Molecular and Cellular Biology. 25: 10052-9. PMID 16260618 DOI: 10.1128/Mcb.25.22.10052-10059.2005  0.392
2005 Kuns R, Kissil JL, Newsham IF, Jacks T, Gutmann DH, Sherman LS. Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation. Oncogene. 24: 6502-15. PMID 16007173 DOI: 10.1038/Sj.Onc.1208813  0.364
2003 Kissil JL, Wilker EW, Johnson KC, Eckman MS, Yaffe MB, Jacks T. Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1. Molecular Cell. 12: 841-9. PMID 14580336 DOI: 10.1016/S1097-2765(03)00382-4  0.424
2002 Johnson KC, Kissil JL, Fry JL, Jacks T. Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene. Oncogene. 21: 5990-7. PMID 12203111 DOI: 10.1038/Sj.Onc.1205693  0.417
2002 Kissil JL, Johnson KC, Eckman MS, Jacks T. Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization. The Journal of Biological Chemistry. 277: 10394-9. PMID 11782491 DOI: 10.1074/Jbc.M200083200  0.35
2000 Inbal B, Shani G, Cohen O, Kissil JL, Kimchi A. Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis Molecular and Cellular Biology. 20: 1044-1054. PMID 10629061 DOI: 10.1128/Mcb.20.3.1044-1054.2000  0.319
1999 Cohen O, Inbal B, Kissil JL, Raveh T, Berissi H, Spivak-Kroizaman T, Feinstein E, Kimchi A. DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. The Journal of Cell Biology. 146: 141-8. PMID 10402466 DOI: 10.1083/Jcb.146.1.141  0.33
1999 Kissil JL, Cohen O, Raveh T, Kimchi A. Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death. The Embo Journal. 18: 353-62. PMID 9889192 DOI: 10.1093/Emboj/18.2.353  0.357
1998 Kissil JL, Kimchi A. Death-associated proteins: from gene identification to the analysis of their apoptotic and tumour suppressive functions. Molecular Medicine Today. 4: 268-74. PMID 9679246 DOI: 10.1016/S1357-4310(98)01263-5  0.37
1997 Kissil JL, Feinstein E, Cohen O, Jones PA, Tsai YC, Knowles MA, Eydmann ME, Kimchi A. DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene. Oncogene. 15: 403-7. PMID 9242376 DOI: 10.1038/Sj.Onc.1201172  0.369
1995 Kissil JL, Deiss LP, Bayewitch M, Raveh T, Khaspekov G, Kimchi A. Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death. The Journal of Biological Chemistry. 270: 27932-6. PMID 7499268 DOI: 10.1074/Jbc.270.46.27932  0.323
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