Joseph L. Kissil - Publications

Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Cell Biology, Oncology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hoxha S, Shepard A, Troutman S, Diao H, Doherty JR, Janiszewska M, Witwicki RM, Pipkin ME, Ja WW, Kareta MS, Kissil JL. YAP-mediated recruitment of YY1 and EZH2 represses transcription of key cell cycle regulators. Cancer Research. PMID 32409309 DOI: 10.1158/0008-5472.CAN-19-2415  0.36
2019 Carper MB, Troutman S, Wagner BL, Byrd KM, Selitsky SR, Parag-Sharma K, Henry EC, Li W, Parker JS, Montgomery SA, Cleveland JL, Williams SE, Kissil JL, Hayes DN, Amelio AL. An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma. Cell Reports. 29: 1660-1674.e7. PMID 31693903 DOI: 10.1016/j.celrep.2019.10.005  0.36
2019 Cui Y, Groth S, Troutman S, Carlstedt A, Sperka T, Riecken LB, Kissil JL, Jin H, Morrison H. The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling. Oncogene. PMID 31312020 DOI: 10.1038/s41388-019-0883-6  0.36
2019 Cui Y, Groth S, Troutman S, Carlstedt A, Sperka T, Riecken LB, Kissil JL, Jin H, Morrison H. The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling. Oncogene. PMID 31312020 DOI: 10.1038/s41388-019-0883-6  0.36
2018 Kota S, Hou S, Guerrant W, Madoux F, Troutman S, Fernandez-Vega V, Alekseeva N, Madala N, Scampavia L, Kissil J, Spicer TP. A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype. Oncogene. PMID 29743592 DOI: 10.1038/s41388-018-0257-5  0.36
2017 Moleirinho S, Hoxha S, Mandati V, Curtale G, Troutman S, Ehmer U, Kissil JL. Regulation of localization and function of the transcriptional co-activator YAP by angiomotin. Elife. 6. PMID 28464980 DOI: 10.7554/eLife.23966  0.36
2016 Troutman S, Moleirinho S, Kota S, Nettles K, Fallahi M, Johnson GL, Kissil JL. Crizotinib inhibits NF2-associated schwannoma through inhibition of focal adhesion kinase 1. Oncotarget. PMID 27363027 DOI: 10.18632/oncotarget.10248  0.96
2016 Guerrant W, Kota S, Troutman S, Mandati V, Fallahi M, Stemmer-Rachamimov A, Kissil JL. YAP mediates tumorigenesis in neurofibromatosis type 2 by promoting cell survival and proliferation through a COX2-EGFR signaling axis. Cancer Research. PMID 27216189 DOI: 10.1158/0008-5472.CAN-15-1144  0.96
2014 Moleirinho S, Guerrant W, Kissil JL. The Angiomotins--from discovery to function. Febs Letters. 588: 2693-703. PMID 24548561 DOI: 10.1016/j.febslet.2014.02.006  0.96
2013 Yi C, Shen Z, Stemmer-Rachamimov A, Dawany N, Troutman S, Showe LC, Liu Q, Shimono A, Sudol M, Holmgren L, Stanger BZ, Kissil JL. The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis. Science Signaling. 6: ra77. PMID 24003254 DOI: 10.1126/scisignal.2004060  0.96
2013 Licciulli S, Maksimoska J, Zhou C, Troutman S, Kota S, Liu Q, Duron S, Campbell D, Chernoff J, Field J, Marmorstein R, Kissil JL. FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas. The Journal of Biological Chemistry. 288: 29105-14. PMID 23960073 DOI: 10.1074/jbc.M113.510933  0.96
2013 Licciulli S, Avila JL, Hanlon L, Troutman S, Cesaroni M, Kota S, Keith B, Simon MC, Puré E, Radtke F, Capobianco AJ, Kissil JL. Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53. Cancer Research. 73: 5974-84. PMID 23943799 DOI: 10.1158/0008-5472.CAN-13-1384  0.96
2013 Avila JL, Kissil JL. Notch signaling in pancreatic cancer: oncogene or tumor suppressor? Trends in Molecular Medicine. 19: 320-7. PMID 23545339 DOI: 10.1016/j.molmed.2013.03.003  0.96
2013 Vaira V, Faversani A, Martin NM, Garlick DS, Ferrero S, Nosotti M, Kissil JL, Bosari S, Altieri DC. Regulation of lung cancer metastasis by Klf4-Numb-like signaling. Cancer Research. 73: 2695-705. PMID 23440423 DOI: 10.1158/0008-5472.CAN-12-4232  0.96
2013 Einheber S, Meng X, Rubin M, Lam I, Mohandas N, An X, Shrager P, Kissil J, Maurel P, Salzer JL. The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons. Glia. 61: 240-53. PMID 23109359 DOI: 10.1002/glia.22430  0.96
2013 Zhou C, Licciulli S, Avila JL, Cho M, Troutman S, Jiang P, Kossenkov AV, Showe LC, Liu Q, Vachani A, Albelda SM, Kissil JL. The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Oncogene. 32: 903-9. PMID 22430205 DOI: 10.1038/onc.2012.99  0.96
2012 Avila JL, Troutman S, Durham A, Kissil JL. Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinoma. Plos One. 7: e52133. PMID 23284900 DOI: 10.1371/journal.pone.0052133  0.96
2012 Fera D, Schultz DC, Hodawadekar S, Reichman M, Donover PS, Melvin J, Troutman S, Kissil JL, Huryn DM, Marmorstein R. Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins. Chemistry & Biology. 19: 518-28. PMID 22520758 DOI: 10.1016/j.chembiol.2012.03.007  0.96
2012 Caino MC, Lopez-Haber C, Kissil JL, Kazanietz MG. Non-small cell lung carcinoma cell motility, rac activation and metastatic dissemination are mediated by protein kinase C epsilon. Plos One. 7: e31714. PMID 22384062 DOI: 10.1371/journal.pone.0031714  0.96
2011 Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL. A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell. 19: 527-40. PMID 21481793 DOI: 10.1016/j.ccr.2011.02.017  0.96
2011 Jung Y, Kissil JL, McCarty JH. β8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 271-7. PMID 21181944 DOI: 10.1002/dvdy.22513  0.96
2010 Licciulli S, Kissil JL. WT1: a weak spot in KRAS-induced transformation. The Journal of Clinical Investigation. 120: 3804-7. PMID 20972324 DOI: 10.1172/JCI44901  0.96
2010 Yi C, Kissil JL. Merlin in organ size control and tumorigenesis: Hippo versus EGFR? Genes & Development. 24: 1673-9. PMID 20713513 DOI: 10.1101/gad.1964810  0.96
2010 Mazumdar J, Hickey MM, Pant DK, Durham AC, Sweet-Cordero A, Vachani A, Jacks T, Chodosh LA, Kissil JL, Simon MC, Keith B. HIF-2alpha deletion promotes Kras-driven lung tumor development. Proceedings of the National Academy of Sciences of the United States of America. 107: 14182-7. PMID 20660313 DOI: 10.1073/pnas.1001296107  0.96
2010 Hanlon L, Avila JL, Demarest RM, Troutman S, Allen M, Ratti F, Rustgi AK, Stanger BZ, Radtke F, Adsay V, Long F, Capobianco AJ, Kissil JL. Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma. Cancer Research. 70: 4280-6. PMID 20484026 DOI: 10.1158/0008-5472.CAN-09-4645  0.96
2010 Yi C, Maksimoska J, Marmorstein R, Kissil JL. Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer. Biochemical Pharmacology. 80: 683-9. PMID 20302846 DOI: 10.1016/j.bcp.2010.03.012  0.96
2010 Horresh I, Bar V, Kissil JL, Peles E. Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2480-9. PMID 20164332 DOI: 10.1523/JNEUROSCI.5225-09.2010  0.96
2010 Kissil JL, Blakeley JO, Ferner RE, Huson SM, Kalamarides M, Mautner VF, McCormick F, Morrison H, Packer R, Ramesh V, Ratner N, Rauen KA, Stevenson DA, Hunter-Schaedle K, North K. What's new in neurofibromatosis? Proceedings from the 2009 NF Conference: new frontiers. American Journal of Medical Genetics. Part A. 152: 269-83. PMID 20082461 DOI: 10.1002/ajmg.a.33189  0.96
2009 Santos AM, Jung J, Aziz N, Kissil JL, Puré E. Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. The Journal of Clinical Investigation. 119: 3613-25. PMID 19920354 DOI: 10.1172/JCI38988  0.96
2008 Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. Journal of the American Chemical Society. 130: 15764-5. PMID 18973295 DOI: 10.1021/ja805555a  0.96
2008 Yi C, Wilker EW, Yaffe MB, Stemmer-Rachamimov A, Kissil JL. Validation of the p21-activated kinases as targets for inhibition in neurofibromatosis type 2 Cancer Research. 68: 7932-7937. PMID 18829550 DOI: 10.1158/0008-5472.CAN-08-0866  0.96
2007 Kissil JL, Walmsley MJ, Hanlon L, Haigis KM, Bender Kim CF, Sweet-Cordero A, Eckman MS, Tuveson DA, Capobianco AJ, Tybulewicz VL, Jacks T. Requirement for Rac1 in a K-ras induced lung cancer in the mouse. Cancer Research. 67: 8089-94. PMID 17804720 DOI: 10.1158/0008-5472.CAN-07-2300  0.96
2007 Wong SY, Haack H, Kissil JL, Barry M, Bronson RT, Shen SS, Whittaker CA, Crowley D, Hynes RO. Protein 4.1B suppresses prostate cancer progression and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12784-9. PMID 17640904 DOI: 10.1073/pnas.0705499104  0.96
2006 Kissil JL, Charest A. New tools for dissecting RON receptor tyrosine kinase oncogenic signaling. Cancer Biology & Therapy. 5: 1187-8. PMID 17012849  0.96
2005 Yi C, McCarty JH, Troutman SA, Eckman MS, Bronson RT, Kissil JL. Loss of the putative tumor suppressor band 4.1B/Dal1 gene is dispensable for normal development and does not predispose to cancer. Molecular and Cellular Biology. 25: 10052-9. PMID 16260618 DOI: 10.1128/MCB.25.22.10052-10059.2005  0.96
2005 Kuns R, Kissil JL, Newsham IF, Jacks T, Gutmann DH, Sherman LS. Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation. Oncogene. 24: 6502-15. PMID 16007173 DOI: 10.1038/sj.onc.1208813  0.96
2003 Kissil JL, Wilker EW, Johnson KC, Eckman MS, Yaffe MB, Jacks T. Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1. Molecular Cell. 12: 841-9. PMID 14580336 DOI: 10.1016/S1097-2765(03)00382-4  0.96
2002 Johnson KC, Kissil JL, Fry JL, Jacks T. Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene. Oncogene. 21: 5990-7. PMID 12203111 DOI: 10.1038/sj.onc.1205693  0.96
2002 Kissil JL, Johnson KC, Eckman MS, Jacks T. Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization. The Journal of Biological Chemistry. 277: 10394-9. PMID 11782491 DOI: 10.1074/jbc.M200083200  0.96
2000 Inbal B, Shani G, Cohen O, Kissil JL, Kimchi A. Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis Molecular and Cellular Biology. 20: 1044-1054. PMID 10629061 DOI: 10.1128/MCB.20.3.1044-1054.2000  0.96
1999 Cohen O, Inbal B, Kissil JL, Raveh T, Berissi H, Spivak-Kroizaman T, Feinstein E, Kimchi A. DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. The Journal of Cell Biology. 146: 141-8. PMID 10402466 DOI: 10.1083/jcb.146.1.141  0.96
1999 Kissil JL, Cohen O, Raveh T, Kimchi A. Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death. The Embo Journal. 18: 353-62. PMID 9889192 DOI: 10.1093/emboj/18.2.353  0.96
1998 Lipschutz JH, Kissil JL. Expression of β-catenin and γ-catenin in epithelial tumor cell lines and characterization of a unique cell line Cancer Letters. 126: 33-41. PMID 9563646 DOI: 10.1016/S0304-3835(97)00522-3  0.96
1997 Kissil JL, Kimchi A. Assignment of death associated protein 3(DAP3) to human chromosome 1q21 by in situ hybridization Cytogenetics and Cell Genetics. 77: 252. PMID 9284927  0.96
1997 Kissil JL, Feinstein E, Cohen O, Jones PA, Tsai YC, Knowles MA, Eydmann ME, Kimchi A. DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene. Oncogene. 15: 403-7. PMID 9242376 DOI: 10.1038/sj.onc.1201172  0.96
1995 Kissil JL, Deiss LP, Bayewitch M, Raveh T, Khaspekov G, Kimchi A. Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death. The Journal of Biological Chemistry. 270: 27932-6. PMID 7499268 DOI: 10.1074/jbc.270.46.27932  0.96
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