Ursula Storb - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Molecular Biology, Cell Biology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Ratnam S, Bozek G, Payne C, Gallagher S, Martin T, Storb U. Ssm1b expression and function in germ cells of adult mice and in early embryos. Molecular Reproduction and Development. PMID 28464323 DOI: 10.1002/mrd.22826  0.48
2014 Ratnam S, Engler P, Bozek G, Mao L, Podlutsky A, Austad S, Martin T, Storb U. Identification of Ssm1b, a novel modifier of DNA methylation, and its expression during mouse embryogenesis. Development (Cambridge, England). 141: 2024-34. PMID 24803651 DOI: 10.1242/dev.105726  1
2013 Kodgire P, Mukkawar P, Ratnam S, Martin TE, Storb U. Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID. The Journal of Experimental Medicine. 210: 1481-92. PMID 23752228 DOI: 10.1084/jem.20121523  1
2012 Kodgire P, Mukkawar P, North JA, Poirier MG, Storb U. Nucleosome stability dramatically impacts the targeting of somatic hypermutation. Molecular and Cellular Biology. 32: 2030-40. PMID 22393257 DOI: 10.1128/MCB.06722-11  1
2010 Ratnam S, Bozek G, Nicolae D, Storb U. The pattern of somatic hypermutation of Ig genes is altered when p53 is inactivated. Molecular Immunology. 47: 2611-8. PMID 20691478 DOI: 10.1016/j.molimm.2010.05.291  1
2010 Tanaka A, Shen HM, Ratnam S, Kodgire P, Storb U. Attracting AID to targets of somatic hypermutation. The Journal of Experimental Medicine. 207: 405-15. PMID 20100870 DOI: 10.1084/jem.20090821  0.44
2009 Storb U, Shen HM, Nicolae D. Somatic hypermutation: processivity of the cytosine deaminase AID and error-free repair of the resulting uracils. Cell Cycle (Georgetown, Tex.). 8: 3097-101. PMID 19738437  1
2009 Shen HM, Poirier MG, Allen MJ, North J, Lal R, Widom J, Storb U. The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription. The Journal of Experimental Medicine. 206: 1057-71. PMID 19380635 DOI: 10.1084/jem.20082678  1
2008 Shen HM, Bozek G, Pinkert CA, McBride K, Wang L, Kenter A, Storb U. Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney. Molecular Immunology. 45: 1883-92. PMID 18067961 DOI: 10.1016/j.molimm.2007.10.041  0.48
2008 Longerich S, Orelli BJ, Martin RW, Bishop DK, Storb U. Brca1 in immunoglobulin gene conversion and somatic hypermutation. Dna Repair. 7: 253-66. PMID 18036997 DOI: 10.1016/j.dnarep.2007.10.002  1
2007 Longerich S, Meira L, Shah D, Samson LD, Storb U. Alkyladenine DNA glycosylase (Aag) in somatic hypermutation and class switch recombination. Dna Repair. 6: 1764-73. PMID 17681497 DOI: 10.1016/j.dnarep.2007.06.012  0.44
2007 Storb U, Shen HM, Longerich S, Ratnam S, Tanaka A, Bozek G, Pylawka S. Targeting of AID to immunoglobulin genes. Advances in Experimental Medicine and Biology. 596: 83-91. PMID 17338178 DOI: 10.1007/0-387-46530-8_8  0.48
2007 Volgina VV, Sun T, Bozek G, Martin TE, Storb U. Scarcity of lambda 1 B cells in mice with a single point mutation in C lambda 1 is due to a low BCR signal caused by misfolded lambda 1 light chain. Molecular Immunology. 44: 1417-28. PMID 16860389 DOI: 10.1016/j.molimm.2006.04.022  1
2006 Shen HM, Tanaka A, Bozek G, Nicolae D, Storb U. Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice. Journal of Immunology (Baltimore, Md. : 1950). 177: 5386-92. PMID 17015724 DOI: 10.4049/jimmunol.177.8.5386  1
2006 Longerich S, Basu U, Alt F, Storb U. AID in somatic hypermutation and class switch recombination. Current Opinion in Immunology. 18: 164-74. PMID 16464563 DOI: 10.1016/j.coi.2006.01.008  1
2006 Longerich S, Basu U, Alt F, Storb U. AID in somatic hypermutation and class switch recombination [Current Opinion in Immunology 2006, 18:164-174] (DOI:10.1016/j.coi.2006.01.008) Current Opinion in Immunology. 18: 769. DOI: 10.1016/j.coi.2006.09.017  1
2005 Shen HM, Ratnam S, Storb U. Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNA. Molecular and Cellular Biology. 25: 10815-21. PMID 16314506 DOI: 10.1128/MCB.25.24.10815-10821.2005  0.4
2005 Longerich S, Tanaka A, Bozek G, Nicolae D, Storb U. The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions. The Journal of Experimental Medicine. 202: 1443-54. PMID 16301749 DOI: 10.1084/jem.20051604  1
2005 Padjen K, Ratnam S, Storb U. DNA methylation precedes chromatin modifications under the influence of the strain-specific modifier Ssm1. Molecular and Cellular Biology. 25: 4782-91. PMID 15899878 DOI: 10.1128/MCB.25.11.4782-4791.2005  0.4
2005 Longerich S, Storb U. The contested role of uracil DNA glycosylase in immunoglobulin gene diversification. Trends in Genetics : Tig. 21: 253-6. PMID 15851057 DOI: 10.1016/j.tig.2005.02.013  0.44
2004 Shen HM, Storb U. Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled. Proceedings of the National Academy of Sciences of the United States of America. 101: 12997-3002. PMID 15328407 DOI: 10.1073/pnas.0404974101  0.4
2003 Michael N, Shen HM, Longerich S, Kim N, Longacre A, Storb U. The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription. Immunity. 19: 235-42. PMID 12932357  1
2003 Longacre A, Sun T, Goldsby RE, Preston BD, Storb U. Ig gene somatic hypermutation in mice defective for DNA polymerase delta proofreading. International Immunology. 15: 477-81. PMID 12663677 DOI: 10.1093/intimm/dxg047  1
2003 Kim N, Martin TE, Simon MC, Storb U. The transcription factor Spi-B is not required for somatic hypermutation. Molecular Immunology. 39: 577-83. PMID 12431391 DOI: 10.1016/S0161-5890(02)00201-8  1
2002 Sun T, Clark MR, Storb U. A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling. Immunity. 16: 245-55. PMID 11869685  1
2002 Michael N, Martin TE, Nicolae D, Kim N, Padjen K, Zhan P, Nguyen H, Pinkert C, Storb U. Effects of sequence and structure on the hypermutability of immunoglobulin genes. Immunity. 16: 123-34. PMID 11825571 DOI: 10.1016/S1074-7613(02)00261-3  1
2001 Sun T, Storb U. Insertion of phosphoglycerine kinase (PGK)-Neo 5′ of Jλ1 dramatically enhances VJλ1 rearrangement Journal of Experimental Medicine. 193: 699-711. PMID 11257137 DOI: 10.1084/jem.193.6.699  1
2001 Storb U, Shen HM, Michael N, Kim N. Somatic hypermutation of immunoglobulin and non-immunoglobulin genes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 13-9. PMID 11205325 DOI: 10.1098/rstb.2000.0743  1
2000 Shen HM, Michael N, Kim N, Storb U. The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells. International Immunology. 12: 1085-93. PMID 10882420  1
1999 Storb U, Peters A, Kim N, Shen HM, Bozek G, Michael N, Hackett J, Klotz E, Reynolds JD, Loeb LA, Martin TE. Molecular aspects of somatic hypermutation of immunoglobulin genes. Cold Spring Harbor Symposia On Quantitative Biology. 64: 227-34. PMID 11232290 DOI: 10.1101/SQB.1999.64.227  1
1999 Sun T, Ezekiel UR, Erskine L, Agulo R, Bozek G, Roth D, Storb U. Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends. Molecular Immunology. 36: 551-8. PMID 10475610  1
1999 Kim N, Bozek G, Lo JC, Storb U. Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications. The Journal of Experimental Medicine. 190: 21-30. PMID 10429667 DOI: 10.1084/jem.190.1.21  1
1998 Storb U, Peters A, Klotz E, Kim N, Shen HM, Hackett J, Rogerson B, O'Brien R, Martin TE. Immunoglobulin transgenes as targets for somatic hypermutation. The International Journal of Developmental Biology. 42: 977-82. PMID 9853828  1
1998 Storb U, Klotz EL, Hackett J, Kage K, Bozek G, Martin TE. A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript. The Journal of Experimental Medicine. 188: 689-98. PMID 9705951 DOI: 10.1084/JEM.188.4.689  0.48
1998 Kim N, Storb U. The role of DNA repair in somatic hypermutation of immunoglobulin genes. The Journal of Experimental Medicine. 187: 1729-33. PMID 9607914  1
1998 Storb U, Peters A, Klotz E, Kim N, Shen HM, Hackett J, Rogerson B, Martin TE. Cis-acting sequences that affect somatic hypermutation of Ig genes. Immunological Reviews. 162: 153-60. PMID 9602361 DOI: 10.1111/j.1600-065X.1998.tb01438.x  1
1998 Storb U, Peters A, Klotz E, Kim N, Shen HM, Kage K, Rogerson B, Martin TE. Somatic hypermutation of immunoglobulin genes is linked to transcription. Current Topics in Microbiology and Immunology. 229: 11-9. PMID 9479844  1
1997 Fuller K, Storb U. Identification and characterization of the murine Rag1 promoter Molecular Immunology. 34: 939-954. PMID 9464529 DOI: 10.1016/S0161-5890(97)00000-X  1
1997 Kim N, Kage K, Matsuda F, Lefranc MP, Storb U. B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes. The Journal of Experimental Medicine. 186: 413-9. PMID 9236193  1
1997 Ezekiel UR, Sun T, Bozek G, Storb U. The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences. Molecular and Cellular Biology. 17: 4191-7. PMID 9199354  1
1997 Kurtz BS, Witte PL, Storb U. γ2b provides only some of the signals normally given via μ in B cell development International Immunology. 9: 415-426. PMID 9088980 DOI: 10.1093/intimm/9.3.415  1
1996 Storb U, Peters A, Klotz E, Rogerson B, Hackett J. The mechanism of somatic hypermutation studied with transgenic and transfected target genes. Seminars in Immunology. 8: 131-40. PMID 8738912 DOI: 10.1006/smim.1996.0017  1
1993 Roth PE, Doglio L, Manz JT, Kim JY, Lo D, Storb U. Immunoglobulin gamma 2b transgenes inhibit heavy chain gene rearrangement, but cannot promote B cell development. The Journal of Experimental Medicine. 178: 2007-21. PMID 8245779 DOI: 10.1084/JEM.178.6.2007  1
1992 Rudin CM, Storb U. Two conserved essential motifs of the murine immunoglobulin lambda enhancers bind B-cell-specific factors. Molecular and Cellular Biology. 12: 309-20. PMID 1729607 DOI: 10.1128/MCB.12.1.309  0.36
1992 Hackett J, Stebbins C, Rogerson B, Davis MM, Storb U. Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism. The Journal of Experimental Medicine. 176: 225-31. PMID 1613457 DOI: 10.1084/JEM.176.1.225  1
1990 Hackett J, Rogerson BJ, O'Brien RL, Storb U. Analysis of somatic mutations in kappa transgenes. The Journal of Experimental Medicine. 172: 131-7. PMID 2358776 DOI: 10.1084/jem.172.1.131  1
1990 Hagman J, Rudin CM, Haasch D, Chaplin D, Storb U. A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B. Genes & Development. 4: 978-92. PMID 2116989 DOI: 10.1101/gad.4.6.978  1
1990 Denis KA, Witte ON, Brinster RL, Provost S, Storb U. Delay of Early B-Lymphocyte Development By Gamma 2b Immunoglobulin Transgene: Effect on Differentiation- Specific Molecules Developmental Immunology. 1: 105-112. PMID 1967016 DOI: 10.1155/1990/71584  1
1989 Hagman J, Lo D, Doglio LT, Hackett J, Rudin CM, Haasch D, Brinster R, Storb U. Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene. The Journal of Experimental Medicine. 169: 1911-29. PMID 2499652 DOI: 10.1084/jem.169.6.1911  1
1988 Manz J, Denis K, Witte O, Brinster R, Storb U. Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains. The Journal of Experimental Medicine. 168: 1363-81. PMID 3139821 DOI: 10.1084/jem.168.4.1363  1
1985 Storb U, Denis KA, Brinster RL, Witte ON. Pre-B cells in κ-transgenic mice Nature. 316: 356-358. PMID 3927171 DOI: 10.1038/316356a0  1
1982 Arp B, McMullen MD, Storb U. Sequences of immunoglobulin lambda 1 genes in a lambda 1 defective mouse strain. Nature. 298: 184-7. PMID 6806667 DOI: 10.1038/298184a0  1
1981 Near RI, Storb U. Immunoglobulin mu- and gamma-ribonucleic acid sequences in thymocytes and splenocytes from normal and hyperimmune mice. Biochemistry. 20: 2386-94. PMID 6165381 DOI: 10.1021/BI00512A004  1
1980 Storb U, Near R, Putnam D, Clagett J. Immunoglobulin messenger RNAs of T lymphocytes. Molecular Immunology. 17: 947-57. PMID 6971400 DOI: 10.1016/0161-5890(80)90043-7  1
1979 Near RI, Storb U. RNA sequences homologous to the 3' portion of immunoglobulin alpha-chain mRNA in thymus-derived lymphocytes. Biochemistry. 18: 964-72. PMID 106877 DOI: 10.1021/BI00573A005  1
1977 Storb U, Hager L, Wilson R, Putnam D. Expression of immunoglobulin and globin genes in B and T lymphocytes and other cells Biochemistry. 16: 5432-5438. PMID 303524 DOI: 10.1021/BI00644A005  1
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