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Sina Ghaemmaghami, Ph.D. - Publications

Affiliations: 
1996-2001 Duke University, Durham, NC 
 2001-2011 University of California, San Francisco, San Francisco, CA 
 2012- University of Rochester, Rochester, NY 
Area:
protein folding, protein translocation, bacterial infection, ribonucleoprotein assembly and cellular signaling
Website:
http://ghaemmaghamilab.org
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Meadow ME, Broas S, Hoare M, Alimohammadi F, Welle KA, Swovick K, Hryhorenko JR, Martinez JC, Biashad SA, Seluanov A, Gorbunova V, Buchwalter A, Ghaemmaghami S. Proteome birthdating reveals age-selectivity of protein ubiquitination. Molecular & Cellular Proteomics : McP. 100791. PMID 38797438 DOI: 10.1016/j.mcpro.2024.100791  0.428
2023 Hasper J, Welle K, Swovick K, Hryhorenko J, Ghaemmaghami S, Buchwalter A. Long lifetime and tissue-specific accumulation of lamin A/C in Hutchinson-Gilford progeria syndrome. The Journal of Cell Biology. 223. PMID 37966721 DOI: 10.1083/jcb.202307049  0.309
2023 Tan R, Hoare M, Welle KA, Swovick K, Hryhorenko JR, Ghaemmaghami S. Folding stabilities of ribosome-bound nascent polypeptides probed by mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303167120. PMID 37552756 DOI: 10.1073/pnas.2303167120  0.757
2023 Hasper J, Welle K, Swovick K, Hryhorenko J, Ghaemmaghami S, Buchwalter A. Long lifetime and selective accumulation of the A-type lamins accounts for the tissue specificity of Hutchinson-Gilford progeria syndrome. Biorxiv : the Preprint Server For Biology. PMID 37162946 DOI: 10.1101/2023.02.04.527139  0.748
2023 Hasper J, Welle K, Hryhorenko J, Ghaemmaghami S, Buchwalter A. Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes. Molecular Systems Biology. 19: e11393. PMID 36929723 DOI: 10.15252/msb.202211393  0.405
2022 Walker EJ, Bettinger JQ, Welle KA, Hryhorenko JR, Molina Vargas AM, O'Connell MR, Ghaemmaghami S. Protein folding stabilities are a major determinant of oxidation rates for buried methionine residues. The Journal of Biological Chemistry. 101872. PMID 35346688 DOI: 10.1016/j.jbc.2022.101872  0.304
2021 Swovick K, Firsanov D, Welle KA, Hryhorenko JR, Wise JP, George C, Sformo TL, Seluanov A, Gorbunova V, Ghaemmaghami S. Interspecies Differences in Proteome Turnover Kinetics Are Correlated With Life Spans and Energetic Demands. Molecular & Cellular Proteomics : McP. 20: 100041. PMID 33639418 DOI: 10.1074/mcp.RA120.002301  0.767
2020 Swovick K, Firsanov D, Welle KA, Hryhorenko J, Wise JP, George C, Sformo TL, Seluanov A, Gorbunova V, Ghaemmaghami S. Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands. Molecular & Cellular Proteomics : McP. PMID 33372049 DOI: 10.1074/mcp.RA120.002301  0.485
2020 Swovick K, Firsanov D, Welle KA, Hryhorenko J, Wise JP, George C, Sformo TL, Seluanov A, Gorbunova V, Ghaemmaghami S. Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands. Molecular & Cellular Proteomics : McP. PMID 33372049 DOI: 10.1074/mcp.RA120.002301  0.485
2020 Lin Y, Zhou X, Kato M, Liu D, Ghaemmaghami S, Tu BP, McKnight SL. Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 33144500 DOI: 10.1073/pnas.2012216117  0.594
2020 Lin Y, Zhou X, Kato M, Liu D, Ghaemmaghami S, Tu BP, McKnight SL. Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 33144500 DOI: 10.1073/pnas.2012216117  0.594
2020 Bettinger J, Ghaemmaghami S. Methionine oxidation within the prion protein. Prion. 14: 193-205. PMID 32744136 DOI: 10.1080/19336896.2020.1796898  0.404
2020 Hutti CR, Welle KA, Hryhorenko JR, Ghaemmaghami S. Publisher Correction: Global analysis of protein degradation in prion infected cells. Scientific Reports. 10: 12952. PMID 32719387 DOI: 10.1038/S41598-020-69657-W  0.394
2020 Hutti CR, Welle KA, Hryhorenko JR, Ghaemmaghami S. Global analysis of protein degradation in prion infected cells. Scientific Reports. 10: 10800. PMID 32612191 DOI: 10.1038/s41598-020-67505-5  0.365
2020 Hutti CR, Welle KA, Hryhorenko JR, Ghaemmaghami S. Global analysis of protein degradation in prion infected cells. Scientific Reports. 10: 10800. PMID 32612191 DOI: 10.1038/S41598-020-67505-5  0.467
2020 Bettinger JQ, Welle KA, Hryhorenko JR, Ghaemmaghami S. Quantitative Analysis of in Vivo Methionine Oxidation of the Human Proteome. Journal of Proteome Research. PMID 31801345 DOI: 10.1021/Acs.Jproteome.9B00505  0.301
2019 Walker EJ, Bettinger JQ, Welle KA, Hryhorenko JR, Ghaemmaghami S. Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome. Proceedings of the National Academy of Sciences of the United States of America. PMID 30846556 DOI: 10.1073/Pnas.1819851116  0.522
2018 Johnson MR, Stephenson RA, Ghaemmaghami S, Welte MA. Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in embryos. Elife. 7. PMID 30044219 DOI: 10.7554/Elife.36021  0.309
2018 Popa-Wagner A, Sandu RE, Cristin C, Uzoni A, Welle KA, Hryhorenko JR, Ghaemmaghami S. Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. Frontiers in Aging Neuroscience. 10: 32. PMID 29503614 DOI: 10.3389/Fnagi.2018.00032  0.333
2018 Swovick K, Welle KA, Hryhorenko J, Seluanov A, Gorbunova V, Ghaemmaghami S. Cross-species comparison of proteome turnover kinetics. Molecular & Cellular Proteomics : McP. PMID 29321186 DOI: 10.1074/Mcp.Ra117.000574  0.749
2017 Zhang T, Wolfe C, Pierle A, Welle KA, Hryhorenko JR, Ghaemmaghami S. Proteome-wide modulation of degradation dynamics in response to growth arrest. Proceedings of the National Academy of Sciences of the United States of America. PMID 29133406 DOI: 10.1073/Pnas.1710238114  0.607
2016 Ghaemmaghami S. Biology and Genetics of PrP Prion Strains. Cold Spring Harbor Perspectives in Medicine. PMID 27920025 DOI: 10.1101/Cshperspect.A026922  0.309
2016 Welle KA, Zhang T, Hyrohorenko JR, Shen S, Qu J, Ghaemmaghami S. Time-resolved analysis of proteome dynamics by TMT-SILAC hyperplexing. Molecular & Cellular Proteomics : McP. PMID 27765818 DOI: 10.1074/Mcp.M116.063230  0.602
2016 Zhang T, Ghaemmaghami S. Global Analysis of Cellular Protein Flux Quantifies the Selectivity of Basal Autophagy. Autophagy. 0. PMID 27248575 DOI: 10.1080/15548627.2016.1190891  0.619
2016 Zhang T, Shen S, Qu J, Ghaemmaghami S. Global Analysis of Cellular Protein Flux Quantifies the Selectivity of Basal Autophagy. Cell Reports. PMID 26947064 DOI: 10.1016/J.Celrep.2016.02.040  0.59
2015 Shen S, Li J, Hilchey S, Shen X, Tu C, Qiu X, Ng A, Ghaemmaghami S, Wu H, ZAnd M, Qu J. An Ion-Current-Based Temporal Proteomic Profiling of Influenza A Virus Infected Mouse Lungs Revealed Underlying Mechanisms of Altered Integrity of the Lung Microvascular Barrier. Journal of Proteome Research. PMID 26650791 DOI: 10.1021/Acs.Jproteome.5B00927  0.326
2014 Zhang T, Price JC, Nouri-Nigjeh E, Li J, Hellerstein MK, Qu J, Ghaemmaghami S. Kinetics of precursor labeling in stable isotope labeling in cell cultures (SILAC) experiments. Analytical Chemistry. 86: 11334-41. PMID 25301408 DOI: 10.1021/Ac503067A  0.514
2014 Price JC, Ghaemmaghami S. Analysis of proteome dynamics in mice by isotopic labeling. Methods in Molecular Biology (Clifton, N.J.). 1156: 111-31. PMID 24791984 DOI: 10.1007/978-1-4939-0685-7_7  0.374
2014 Ghaemmaghami S, Russo M, Renslo AR. Successes and challenges in phenotype-based lead discovery for prion diseases. Journal of Medicinal Chemistry. 57: 6919-29. PMID 24762293 DOI: 10.1021/Jm5001425  0.418
2014 Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S. Analysis of proteome dynamics in themouse brain (vol 107, pg 14508, 2010) Proceedings of the National Academy of Sciences of the United States of America. 111: 3645-3645. DOI: 10.1073/Pnas.1401576111  0.422
2013 Silber BM, Gever JR, Li Z, Gallardo-Godoy A, Renslo AR, Widjaja K, Irwin JJ, Rao S, Jacobson MP, Ghaemmaghami S, Prusiner SB. Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells. Bioorganic & Medicinal Chemistry. 21: 7999-8012. PMID 24183589 DOI: 10.1016/J.Bmc.2013.09.022  0.458
2013 Miller-Vedam L, Ghaemmaghami S. Strain specificity and drug resistance in anti-prion therapy. Current Topics in Medicinal Chemistry. 13: 2397-406. PMID 24059341 DOI: 10.2174/15680266113136660168  0.33
2013 Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. Convergent replication of mouse synthetic prion strains. The American Journal of Pathology. 182: 866-74. PMID 23438476 DOI: 10.1016/J.Ajpath.2012.11.038  0.526
2012 Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice. Molecular Therapy. Nucleic Acids. 1: e9. PMID 23344724 DOI: 10.1038/Mtna.2011.6  0.518
2012 Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB. Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter. Plos One. 7: e39112. PMID 22768295 DOI: 10.1371/Journal.Pone.0039112  0.414
2012 Guan S, Price JC, Ghaemmaghami S, Prusiner SB, Burlingame AL. Compartment modeling for mammalian protein turnover studies by stable isotope metabolic labeling. Analytical Chemistry. 84: 4014-21. PMID 22444387 DOI: 10.1021/Ac203330Z  0.586
2011 Guan S, Price JC, Prusiner SB, Ghaemmaghami S, Burlingame AL. A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling. Molecular & Cellular Proteomics : McP. 10: M111.010728. PMID 21937731 DOI: 10.1074/Mcp.M111.010728  0.549
2011 Ghaemmaghami S, Watts JC, Nguyen HO, Hayashi S, DeArmond SJ, Prusiner SB. Conformational transformation and selection of synthetic prion strains. Journal of Molecular Biology. 413: 527-42. PMID 21839745 DOI: 10.1016/J.Jmb.2011.07.021  0.676
2011 Poncet-Montange G, St Martin SJ, Bogatova OV, Prusiner SB, Shoichet BK, Ghaemmaghami S. A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets. The Journal of Biological Chemistry. 286: 27718-28. PMID 21610081 DOI: 10.1074/Jbc.M111.234393  0.509
2010 Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S. Analysis of proteome dynamics in the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 14508-13. PMID 20699386 DOI: 10.1073/Pnas.1006551107  0.627
2010 Ghaemmaghami S, May BC, Renslo AR, Prusiner SB. Discovery of 2-aminothiazoles as potent antiprion compounds. Journal of Virology. 84: 3408-12. PMID 20032192 DOI: 10.1128/Jvi.02145-09  0.498
2010 Ghaemmaghami S, Ullman J, Ahn M, St Martin S, Prusiner SB. Chemical induction of misfolded prion protein conformers in cell culture. The Journal of Biological Chemistry. 285: 10415-23. PMID 19955177 DOI: 10.1074/Jbc.M109.045112  0.502
2009 Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB. Continuous quinacrine treatment results in the formation of drug-resistant prions. Plos Pathogens. 5: e1000673. PMID 19956709 DOI: 10.1371/Journal.Ppat.1000673  0.454
2009 Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science (New York, N.Y.). 324: 218-23. PMID 19213877 DOI: 10.1126/Science.1168978  0.718
2007 Ghaemmaghami S, Phuan PW, Perkins B, Ullman J, May BC, Cohen FE, Prusiner SB. Cell division modulates prion accumulation in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 17971-6. PMID 17989223 DOI: 10.1073/Pnas.0708372104  0.494
2006 Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature. 441: 840-6. PMID 16699522 DOI: 10.1038/Nature04785  0.794
2005 Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK. Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. Comparative and Functional Genomics. 6: 2-16. PMID 18629296 DOI: 10.1002/Cfg.449  0.638
2003 Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. Global analysis of protein expression in yeast. Nature. 425: 737-41. PMID 14562106 DOI: 10.1038/Nature02046  0.613
2002 Powell KD, Ghaemmaghami S, Wang MZ, Ma L, Oas TG, Fitzgerald MC. A general mass spectrometry-based assay for the quantitation of protein-ligand binding interactions in solution. Journal of the American Chemical Society. 124: 10256-7. PMID 12197709 DOI: 10.1021/Ja026574G  0.683
2001 Ghaemmaghami S, Oas TG. Quantitative protein stability measurement in vivo. Nature Structural Biology. 8: 879-82. PMID 11573094 DOI: 10.1038/Nsb1001-879  0.718
2000 Ghaemmaghami S, Fitzgerald MC, Oas TG. A quantitative, high-throughput screen for protein stability. Proceedings of the National Academy of Sciences of the United States of America. 97: 8296-301. PMID 10890887 DOI: 10.1073/Pnas.140111397  0.704
1998 Ghaemmaghami S, Word JM, Burton RE, Richardson JS, Oas TG. Folding kinetics of a fluorescent variant of monomeric lambda repressor. Biochemistry. 37: 9179-85. PMID 9636065 DOI: 10.1021/bi980356b  0.604
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