Sina Ghaemmaghami, Ph.D. - Publications

1996-2001 Duke University, Durham, NC 
 2001-2011 University of California, San Francisco, San Francisco, CA 
 2012- University of Rochester, Rochester, NY 
protein folding, protein translocation, bacterial infection, ribonucleoprotein assembly and cellular signaling

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhang T, Shen S, Qu J, Ghaemmaghami S. Global Analysis of Cellular Protein Flux Quantifies the Selectivity of Basal Autophagy. Cell Reports. PMID 26947064 DOI: 10.1016/j.celrep.2016.02.040  1
2015 Shen S, Li J, Hilchey S, Shen X, Tu C, Qiu X, Ng A, Ghaemmaghami S, Wu H, ZAnd M, Qu J. An Ion-Current-Based Temporal Proteomic Profiling of Influenza A Virus Infected Mouse Lungs Revealed Underlying Mechanisms of Altered Integrity of the Lung Microvascular Barrier. Journal of Proteome Research. PMID 26650791 DOI: 10.1021/acs.jproteome.5b00927  1
2014 Zhang T, Price JC, Nouri-Nigjeh E, Li J, Hellerstein MK, Qu J, Ghaemmaghami S. Kinetics of precursor labeling in stable isotope labeling in cell cultures (SILAC) experiments. Analytical Chemistry. 86: 11334-41. PMID 25301408 DOI: 10.1021/ac503067a  1
2014 Price JC, Ghaemmaghami S. Analysis of proteome dynamics in mice by isotopic labeling. Methods in Molecular Biology (Clifton, N.J.). 1156: 111-31. PMID 24791984 DOI: 10.1007/978-1-4939-0685-7_7  1
2014 Ghaemmaghami S, Russo M, Renslo AR. Successes and challenges in phenotype-based lead discovery for prion diseases. Journal of Medicinal Chemistry. 57: 6919-29. PMID 24762293 DOI: 10.1021/jm5001425  1
2013 Silber BM, Gever JR, Li Z, Gallardo-Godoy A, Renslo AR, Widjaja K, Irwin JJ, Rao S, Jacobson MP, Ghaemmaghami S, Prusiner SB. Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells. Bioorganic & Medicinal Chemistry. 21: 7999-8012. PMID 24183589 DOI: 10.1016/j.bmc.2013.09.022  1
2013 Miller-Vedam L, Ghaemmaghami S. Strain specificity and drug resistance in anti-prion therapy. Current Topics in Medicinal Chemistry. 13: 2397-406. PMID 24059341  1
2013 Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. Convergent replication of mouse synthetic prion strains. The American Journal of Pathology. 182: 866-74. PMID 23438476 DOI: 10.1016/j.ajpath.2012.11.038  1
2012 Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice. Molecular Therapy. Nucleic Acids. 1: e9. PMID 23344724 DOI: 10.1038/mtna.2011.6  1
2012 Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB. Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter. Plos One. 7: e39112. PMID 22768295 DOI: 10.1371/journal.pone.0039112  1
2012 Guan S, Price JC, Ghaemmaghami S, Prusiner SB, Burlingame AL. Compartment modeling for mammalian protein turnover studies by stable isotope metabolic labeling. Analytical Chemistry. 84: 4014-21. PMID 22444387 DOI: 10.1021/ac203330z  1
2011 Guan S, Price JC, Prusiner SB, Ghaemmaghami S, Burlingame AL. A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling. Molecular & Cellular Proteomics : McP. 10: M111.010728. PMID 21937731 DOI: 10.1074/mcp.M111.010728  1
2011 Ghaemmaghami S, Watts JC, Nguyen HO, Hayashi S, DeArmond SJ, Prusiner SB. Conformational transformation and selection of synthetic prion strains. Journal of Molecular Biology. 413: 527-42. PMID 21839745 DOI: 10.1016/j.jmb.2011.07.021  1
2011 Poncet-Montange G, St Martin SJ, Bogatova OV, Prusiner SB, Shoichet BK, Ghaemmaghami S. A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets. The Journal of Biological Chemistry. 286: 27718-28. PMID 21610081 DOI: 10.1074/jbc.M111.234393  1
2010 Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S. Analysis of proteome dynamics in the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 14508-13. PMID 20699386 DOI: 10.1073/pnas.1006551107  1
2010 Ghaemmaghami S, May BC, Renslo AR, Prusiner SB. Discovery of 2-aminothiazoles as potent antiprion compounds. Journal of Virology. 84: 3408-12. PMID 20032192 DOI: 10.1128/JVI.02145-09  1
2010 Ghaemmaghami S, Ullman J, Ahn M, St Martin S, Prusiner SB. Chemical induction of misfolded prion protein conformers in cell culture. The Journal of Biological Chemistry. 285: 10415-23. PMID 19955177 DOI: 10.1074/jbc.M109.045112  1
2009 Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB. Continuous quinacrine treatment results in the formation of drug-resistant prions. Plos Pathogens. 5: e1000673. PMID 19956709 DOI: 10.1371/journal.ppat.1000673  1
2009 Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science (New York, N.Y.). 324: 218-23. PMID 19213877 DOI: 10.1126/science.1168978  1
2007 Ghaemmaghami S, Phuan PW, Perkins B, Ullman J, May BC, Cohen FE, Prusiner SB. Cell division modulates prion accumulation in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 17971-6. PMID 17989223 DOI: 10.1073/pnas.0708372104  1
2006 Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature. 441: 840-6. PMID 16699522 DOI: 10.1038/nature04785  1
2005 Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK. Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. Comparative and Functional Genomics. 6: 2-16. PMID 18629296 DOI: 10.1002/cfg.449  1
2003 Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. Global analysis of protein expression in yeast. Nature. 425: 737-41. PMID 14562106 DOI: 10.1038/nature02046  1
2002 Powell KD, Ghaemmaghami S, Wang MZ, Ma L, Oas TG, Fitzgerald MC. A general mass spectrometry-based assay for the quantitation of protein-ligand binding interactions in solution. Journal of the American Chemical Society. 124: 10256-7. PMID 12197709 DOI: 10.1021/ja026574g  1
2001 Ghaemmaghami S, Oas TG. Quantitative protein stability measurement in vivo. Nature Structural Biology. 8: 879-82. PMID 11573094 DOI: 10.1038/nsb1001-879  1
2000 Ghaemmaghami S, Fitzgerald MC, Oas TG. A quantitative, high-throughput screen for protein stability. Proceedings of the National Academy of Sciences of the United States of America. 97: 8296-301. PMID 10890887 DOI: 10.1073/pnas.140111397  1
1998 Ghaemmaghami S, Word JM, Burton RE, Richardson JS, Oas TG. Folding kinetics of a fluorescent variant of monomeric lambda repressor. Biochemistry. 37: 9179-85. PMID 9636065 DOI: 10.1021/bi980356b  1
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