Wesley I. Sundquist - Publications

Affiliations: 
University of Utah, Salt Lake City, UT 
Area:
Biochemistry

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Scott TM, Arnold LM, Powers JA, McCann DA, Christensen DE, Zhou W, Torrez RM, Iwasa JH, Kranzusch PJ, Sundquist WI, Johnson JS. Cell-free assays reveal the HIV-1 capsid protects reverse transcripts from cGAS. Biorxiv : the Preprint Server For Biology. PMID 38712059 DOI: 10.1101/2024.04.22.590513  0.319
2023 Paine EL, Skalicky JJ, Whitby FG, Mackay DR, Ullman KS, Hill CP, Sundquist WI. The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission. Elife. 12. PMID 37772788 DOI: 10.7554/eLife.84515  0.356
2022 Wenzel DM, Mackay DR, Skalicky JJ, Paine EL, Miller MS, Ullman KS, Sundquist WI. Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission. Elife. 11. PMID 36107470 DOI: 10.7554/eLife.77779  0.366
2021 Rheinemann L, Downhour DM, Bredbenner K, Mercenne G, Davenport KA, Schmitt PT, Necessary CR, McCullough J, Schmitt AP, Simon SM, Sundquist WI, Elde NC. RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis. Cell. PMID 34597582 DOI: 10.1016/j.cell.2021.09.008  0.333
2021 Rheinemann L, Thompson T, Mercenne G, Paine EL, Peterson FC, Volkman BF, Alam SL, Alian A, Sundquist WI. Interactions between AMOT PPxY Motifs and NEDD4L WW Domains Function in HIV-1 Release. The Journal of Biological Chemistry. 100975. PMID 34284061 DOI: 10.1016/j.jbc.2021.100975  0.45
2020 Christensen DE, Ganser-Pornillos BK, Johnson JS, Pornillos O, Sundquist WI. Reconstitution and visualization of HIV-1 capsid-dependent replication and integration in vitro. Science (New York, N.Y.). 370. PMID 33033190 DOI: 10.1126/science.abc8420  0.686
2020 Link JO, Rhee MS, Tse WC, Zheng J, Somoza JR, Rowe W, Begley R, Chiu A, Mulato A, Hansen D, Singer E, Tsai LK, Bam RA, Chou CH, Canales E, ... ... Sundquist WI, et al. Clinical targeting of HIV capsid protein with a long-acting small molecule. Nature. PMID 32612233 DOI: 10.1038/S41586-020-2443-1  0.446
2020 Nguyen HC, Talledge N, McCullough J, Sharma A, Moss FR, Iwasa JH, Vershinin MD, Sundquist WI, Frost A. Membrane constriction and thinning by sequential ESCRT-III polymerization. Nature Structural & Molecular Biology. PMID 32251413 DOI: 10.1038/s41594-020-0404-x  0.303
2019 Yant SR, Mulato A, Hansen D, Tse WC, Niedziela-Majka A, Zhang JR, Stepan GJ, Jin D, Wong MH, Perreira JM, Singer E, Papalia GA, Hu EY, Zheng J, Lu B, ... ... Sundquist WI, et al. A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model. Nature Medicine. 25: 1377-1384. PMID 31501601 DOI: 10.1038/S41591-019-0560-X  0.437
2019 Han H, Fulcher JM, Dandey VP, Iwasa JH, Sundquist WI, Kay MS, Shen PS, Hill CP. Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases. Elife. 8. PMID 31184588 DOI: 10.7554/Elife.44071  0.364
2019 Nguyen HC, Talledge N, McCullough J, Sundquist WI, Frost A. The Structural Basis of a Membrane-Bound ESCRT-III Helical Assembly Biophysical Journal. 116: 180a. DOI: 10.1016/J.Bpj.2018.11.1000  0.33
2018 Sundquist WI, Pornillos O. Retrovirus Restriction by TRIM5α: RINGside at a Cage Fight. Cell Host & Microbe. 24: 751-753. PMID 30543772 DOI: 10.1016/J.Chom.2018.11.013  0.676
2018 Sadler JBA, Wenzel DM, Williams LK, Guindo-Martínez M, Alam SL, Mercader JM, Torrents D, Ullman KS, Sundquist WI, Martin-Serrano J. A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability. Proceedings of the National Academy of Sciences of the United States of America. PMID 30181294 DOI: 10.2210/Pdb5Wa1/Pdb  0.325
2018 McCullough J, Frost A, Sundquist WI. Structures, Functions, and Dynamics of ESCRT-III/Vps4 Membrane Remodeling and Fission Complexes. Annual Review of Cell and Developmental Biology. PMID 30095293 DOI: 10.1146/Annurev-Cellbio-100616-060600  0.327
2017 Wagner JM, Christensen DE, Bhattacharya A, Dawidziak DM, Roganowicz MD, Wan Y, Pumroy RA, Demeler B, Ivanov DN, Ganser-Pornillos BK, Sundquist WI, Pornillos O. A general model for retroviral capsid pattern recognition by TRIM5 proteins. Journal of Virology. PMID 29187540 DOI: 10.1128/Jvi.01563-17  0.778
2017 Han H, Monroe N, Sundquist WI, Shen PS, Hill CP. The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets. Elife. 6. PMID 29165244 DOI: 10.7554/Elife.31324  0.398
2017 Monroe N, Han H, Shen PS, Sundquist WI, Hill CP. Structural Basis of Protein Translocation by the Vps4-Vta1 AAA ATPase. Elife. 6. PMID 28379137 DOI: 10.7554/Elife.24487  0.458
2017 Gu M, LaJoie D, Chen OS, von Appen A, Ladinsky MS, Redd MJ, Nikolova L, Bjorkman PJ, Sundquist WI, Ullman KS, Frost A. LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28242692 DOI: 10.1073/Pnas.1613916114  0.429
2017 Han H, Monroe N, Sundquist WI, Shen PS, Hill CP. Author response: The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets Elife. DOI: 10.7554/Elife.31324.059  0.326
2017 Monroe N, Han H, Shen PS, Sundquist WI, Hill CP. Author response: Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase Elife. DOI: 10.7554/Elife.24487.060  0.375
2016 Votteler J, Ogohara C, Yi S, Hsia Y, Nattermann U, Belnap DM, King NP, Sundquist WI. Designed proteins induce the formation of nanocage-containing extracellular vesicles. Nature. PMID 27919066 DOI: 10.1038/Nature20607  0.422
2016 Li YL, Chandrasekaran V, Carter SD, Woodward CL, Christensen DE, Dryden KA, Pornillos O, Yeager M, Ganser-Pornillos BK, Jensen GJ, Sundquist WI. Primate TRIM5 proteins form hexagonal nets 1 on HIV-1 capsids. Elife. 5. PMID 27253068 DOI: 10.7554/Elife.16269  0.788
2016 Wagner JM, Roganowicz MD, Skorupka K, Alam SL, Christensen DE, Doss GL, Wan Y, Frank GA, Ganser-Pornillos BK, Sundquist WI, Pornillos O. Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α. Elife. 5. PMID 27253059 DOI: 10.7554/Elife.16309  0.736
2016 Wagner JM, Roganowicz MD, Skorupka K, Alam SL, Christensen D, Doss G, Wan Y, Frank GA, Ganser-Pornillos BK, Sundquist WI, Pornillos O. Author response: Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α Elife. DOI: 10.7554/Elife.16309.031  0.672
2016 Li Y, Chandrasekaran V, Carter SD, Woodward CL, Christensen DE, Dryden KA, Pornillos O, Yeager M, Ganser-Pornillos BK, Jensen GJ, Sundquist WI. Author response: Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids Elife. DOI: 10.7554/Elife.16269.022  0.721
2015 McCullough J, Clippinger AK, Talledge N, Skowyra ML, Saunders MG, Naismith TV, Colf LA, Afonine P, Arthur C, Sundquist WI, Hanson PI, Frost A. Structure and membrane remodeling activity of ESCRT-III helical polymers. Science (New York, N.Y.). PMID 26634441 DOI: 10.1126/Science.Aad8305  0.415
2015 Fletcher AJ, Christensen DE, Nelson C, Tan CP, Schaller T, Lehner PJ, Sundquist WI, Towers GJ. TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription. The Embo Journal. PMID 26101372 DOI: 10.15252/Embj.201490361  0.329
2015 Caballe A, Wenzel DM, Agromayor M, Alam SL, Skalicky JJ, Kloc M, Carlton JG, Labrador L, Sundquist WI, Martin-Serrano J. ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins. Elife. 4: e06547. PMID 26011858 DOI: 10.7554/Elife.06547  0.326
2015 Han H, Monroe N, Votteler J, Shakya B, Sundquist WI, Hill CP. Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs). The Journal of Biological Chemistry. 290: 13490-9. PMID 25833946 DOI: 10.1074/Jbc.M115.642355  0.469
2015 Mercenne G, Alam SL, Arii J, Lalonde MS, Sundquist WI. Angiomotin functions in HIV-1 assembly and budding. Elife. 4. PMID 25633977 DOI: 10.7554/Elife.03778  0.421
2015 Caballe A, Wenzel DM, Agromayor M, Alam SL, Skalicky JJ, Kloc M, Carlton JG, Labrador L, Sundquist WI, Martin-Serrano J. Author response: ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins Elife. DOI: 10.7554/Elife.06547.048  0.308
2015 Mercenne G, Alam SL, Arii J, Lalonde MS, Sundquist WI. Author response: Angiomotin functions in HIV-1 assembly and budding Elife. DOI: 10.7554/Elife.03778.023  0.409
2014 McCullough J, Sundquist WI. Putting a finger in the ring. Nature Structural & Molecular Biology. 21: 1025-7. PMID 25469842 DOI: 10.1038/Nsmb.2928  0.411
2014 Sanchez JG, Okreglicka K, Chandrasekaran V, Welker JM, Sundquist WI, Pornillos O. The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer. Proceedings of the National Academy of Sciences of the United States of America. 111: 2494-9. PMID 24550273 DOI: 10.1073/Pnas.1318962111  0.767
2014 Monroe N, Han H, Gonciarz MD, Eckert DM, Karren MA, Whitby FG, Sundquist WI, Hill CP. The oligomeric state of the active Vps4 AAA ATPase. Journal of Molecular Biology. 426: 510-25. PMID 24161953 DOI: 10.1016/J.Jmb.2013.09.043  0.426
2013 Sandrin V, Sundquist WI. ESCRT requirements for EIAV budding. Retrovirology. 10: 104. PMID 24107264 DOI: 10.1186/1742-4690-10-104  0.444
2013 Votteler J, Sundquist WI. Virus budding and the ESCRT pathway. Cell Host & Microbe. 14: 232-41. PMID 24034610 DOI: 10.1016/J.Chom.2013.08.012  0.405
2013 Lamorte L, Titolo S, Lemke CT, Goudreau N, Mercier JF, Wardrop E, Shah VB, von Schwedler UK, Langelier C, Banik SS, Aiken C, Sundquist WI, Mason SW. Discovery of novel small-molecule HIV-1 replication inhibitors that stabilize capsid complexes. Antimicrobial Agents and Chemotherapy. 57: 4622-31. PMID 23817385 DOI: 10.1128/Aac.00985-13  0.462
2013 Hill CP, Sundquist WI. Building a super elongation complex for HIV. Elife. 2: e00577. PMID 23538671 DOI: 10.7554/Elife.00577  0.44
2013 McCullough J, Colf LA, Sundquist WI. Membrane fission reactions of the mammalian ESCRT pathway. Annual Review of Biochemistry. 82: 663-92. PMID 23527693 DOI: 10.1146/Annurev-Biochem-072909-101058  0.363
2013 Effantin G, Dordor A, Sandrin V, Martinelli N, Sundquist WI, Schoehn G, Weissenhorn W. ESCRT-III CHMP2A and CHMP3 form variable helical polymers in vitro and act synergistically during HIV-1 budding. Cellular Microbiology. 15: 213-26. PMID 23051622 DOI: 10.1111/Cmi.12041  0.435
2013 Sundquist WI. The ESCRT Pathway in HIV Budding and Cell Division Biophysical Journal. 104: 12a. DOI: 10.1016/J.Bpj.2012.11.097  0.338
2013 Ganser-Pornillos BK, Pornillos O, Chandrasekaran V, Cheng A, Sundquist WI, Yeager M. The HIV-1 Capsid: Assembly and Restriction by TRIM5α Biophysical Journal. 104: 12a. DOI: 10.1016/J.Bpj.2012.11.096  0.739
2012 Dowlatshahi DP, Sandrin V, Vivona S, Shaler TA, Kaiser SE, Melandri F, Sundquist WI, Kopito RR. ALIX is a Lys63-specific polyubiquitin binding protein that functions in retrovirus budding. Developmental Cell. 23: 1247-54. PMID 23201121 DOI: 10.1016/J.Devcel.2012.10.023  0.451
2012 Lalonde MS, Sundquist WI. How HIV finds the door. Proceedings of the National Academy of Sciences of the United States of America. 109: 18631-2. PMID 23118338 DOI: 10.1073/Pnas.1215940109  0.446
2012 Skalicky JJ, Arii J, Wenzel DM, Stubblefield WM, Katsuyama A, Uter NT, Bajorek M, Myszka DG, Sundquist WI. Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport. The Journal of Biological Chemistry. 287: 43910-26. PMID 23105106 DOI: 10.1074/Jbc.M112.417899  0.804
2012 Morita E, Arii J, Christensen D, Votteler J, Sundquist WI. Attenuated protein expression vectors for use in siRNA rescue experiments. Biotechniques. 1-5. PMID 22877307 DOI: 10.2144/000113909  0.361
2012 Sundquist WI, Kräusslich HG. HIV-1 assembly, budding, and maturation. Cold Spring Harbor Perspectives in Medicine. 2: a006924. PMID 22762019 DOI: 10.1101/Cshperspect.A006924  0.467
2012 Lemke CT, Titolo S, von Schwedler U, Goudreau N, Mercier JF, Wardrop E, Faucher AM, Coulombe R, Banik SS, Fader L, Gagnon A, Kawai SH, Rancourt J, Tremblay M, Yoakim C, ... ... Sundquist WI, et al. Distinct effects of two HIV-1 capsid assembly inhibitor families that bind the same site within the N-terminal domain of the viral CA protein. Journal of Virology. 86: 6643-55. PMID 22496222 DOI: 10.1128/Jvi.00493-12  0.478
2012 Sundquist WI, Krug RM. Assemble, replicate, remodel and evade. Current Opinion in Virology. 2: 111-4. PMID 22482706 DOI: 10.1016/J.Coviro.2012.02.008  0.339
2012 Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, ... ... Sundquist WI, et al. Global landscape of HIV-human protein complexes. Nature. 481: 365-70. PMID 22190034 DOI: 10.1038/Nature10719  0.5
2012 Morita E, Sandrin V, Chung H, Morham SG, Gygi SP, Rodesch CK, Sundquist WI. Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis The Embo Journal. 31: 3228-3228. DOI: 10.1038/Emboj.2012.184  0.377
2011 Zhai Q, Landesman MB, Robinson H, Sundquist WI, Hill CP. Structure of the Bro1 domain protein BROX and functional analyses of the ALIX Bro1 domain in HIV-1 budding. Plos One. 6: e27466. PMID 22162750 DOI: 10.1371/Journal.Pone.0027466  0.832
2011 Zhai Q, Landesman MB, Chung HY, Dierkers A, Jeffries CM, Trewhella J, Hill CP, Sundquist WI. Activation of the retroviral budding factor ALIX. Journal of Virology. 85: 9222-6. PMID 21715492 DOI: 10.1128/Jvi.02653-10  0.803
2011 Morita E, Sandrin V, McCullough J, Katsuyama A, Baci Hamilton I, Sundquist WI. ESCRT-III protein requirements for HIV-1 budding. Cell Host & Microbe. 9: 235-42. PMID 21396898 DOI: 10.1016/J.Chom.2011.02.004  0.812
2011 Ganser-Pornillos BK, Chandrasekaran V, Pornillos O, Sodroski JG, Sundquist WI, Yeager M. Hexagonal assembly of a restricting TRIM5alpha protein. Proceedings of the National Academy of Sciences of the United States of America. 108: 534-9. PMID 21187419 DOI: 10.1073/Pnas.1013426108  0.769
2011 Zhai Q, Landesman MB, Robinson H, Sundquist WI, Hill CP. Identification and structural characterization of the ALIX-binding late domains of simian immunodeficiency virus SIVmac239 and SIVagmTan-1. Journal of Virology. 85: 632-7. PMID 20962096 DOI: 10.1128/Jvi.01683-10  0.817
2010 Schubert HL, Zhai Q, Sandrin V, Eckert DM, Garcia-Maya M, Saul L, Sundquist WI, Steiner RA, Hill CP. Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations. Proceedings of the National Academy of Sciences of the United States of America. 107: 17951-6. PMID 20880831 DOI: 10.1073/Pnas.1008206107  0.507
2010 Morita E, Colf LA, Karren MA, Sandrin V, Rodesch CK, Sundquist WI. Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance. Proceedings of the National Academy of Sciences of the United States of America. 107: 12889-94. PMID 20616062 DOI: 10.1073/Pnas.1005938107  0.402
2010 Zhai Q, Landesman M, Robinson H, Sundquist WI, Hill CP. Identification and Structural Characterization of the Alix-Binding Late Domains of Sivmac239 and Sivagmtan-1. Journal of Virology. 85: 632-637. DOI: 10.2210/Pdb2Xs1/Pdb  0.791
2009 Bajorek M, Schubert HL, McCullough J, Langelier C, Eckert DM, Stubblefield WM, Uter NT, Myszka DG, Hill CP, Sundquist WI. Structural basis for ESCRT-III protein autoinhibition. Nature Structural & Molecular Biology. 16: 754-62. PMID 19525971 DOI: 10.1038/Nsmb.1621  0.521
2009 Pornillos O, Ganser-Pornillos BK, Kelly BN, Hua Y, Whitby FG, Stout CD, Sundquist WI, Hill CP, Yeager M. X-ray structures of the hexameric building block of the HIV capsid. Cell. 137: 1282-92. PMID 19523676 DOI: 10.1016/J.Cell.2009.04.063  0.754
2009 Bajorek M, Morita E, Skalicky JJ, Morham SG, Babst M, Sundquist WI. Biochemical analyses of human IST1 and its function in cytokinesis. Molecular Biology of the Cell. 20: 1360-73. PMID 19129479 DOI: 10.1091/Mbc.E08-05-0475  0.467
2009 Sundquist WI. Mechanistic Studies of HIV Budding Biophysical Journal. 96: 14a. DOI: 10.1016/J.Bpj.2008.12.971  0.526
2008 Gonciarz MD, Whitby FG, Eckert DM, Kieffer C, Heroux A, Sundquist WI, Hill CP. Biochemical and structural studies of yeast Vps4 oligomerization. Journal of Molecular Biology. 384: 878-95. PMID 18929572 DOI: 10.1016/J.Jmb.2008.09.066  0.513
2008 Langelier CR, Sandrin V, Eckert DM, Christensen DE, Chandrasekaran V, Alam SL, Aiken C, Olsen JC, Kar AK, Sodroski JG, Sundquist WI. Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunodeficiency virus type 1 replication. Journal of Virology. 82: 11682-94. PMID 18799573 DOI: 10.1128/Jvi.01562-08  0.504
2008 Kieffer C, Skalicky JJ, Morita E, De Domenico I, Ward DM, Kaplan J, Sundquist WI. Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding. Developmental Cell. 15: 62-73. PMID 18606141 DOI: 10.1016/J.Devcel.2008.05.014  0.577
2008 McCullough J, Fisher RD, Whitby FG, Sundquist WI, Hill CP. ALIX-CHMP4 interactions in the human ESCRT pathway. Proceedings of the National Academy of Sciences of the United States of America. 105: 7687-91. PMID 18511562 DOI: 10.1073/Pnas.0801567105  0.56
2008 Ganser-Pornillos BK, Yeager M, Sundquist WI. The structural biology of HIV assembly. Current Opinion in Structural Biology. 18: 203-17. PMID 18406133 DOI: 10.1016/J.Sbi.2008.02.001  0.515
2008 Chung HY, Morita E, von Schwedler U, Müller B, Kräusslich HG, Sundquist WI. NEDD4L overexpression rescues the release and infectivity of human immunodeficiency virus type 1 constructs lacking PTAP and YPXL late domains. Journal of Virology. 82: 4884-97. PMID 18321968 DOI: 10.1128/Jvi.02667-07  0.562
2008 Yu Z, Gonciarz MD, Sundquist WI, Hill CP, Jensen GJ. Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p. Journal of Molecular Biology. 377: 364-77. PMID 18280501 DOI: 10.1016/J.Jmb.2008.01.009  0.449
2008 Zhai Q, Fisher RD, Chung HY, Myszka DG, Sundquist WI, Hill CP. Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV. Nature Structural & Molecular Biology. 15: 43-9. PMID 18066081 DOI: 10.1038/Nsmb1319  0.522
2007 Neil SJ, Sandrin V, Sundquist WI, Bieniasz PD. An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein. Cell Host & Microbe. 2: 193-203. PMID 18005734 DOI: 10.1016/J.Chom.2007.08.001  0.459
2007 Morita E, Sandrin V, Alam SL, Eckert DM, Gygi SP, Sundquist WI. Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. Cell Host & Microbe. 2: 41-53. PMID 18005716 DOI: 10.1016/J.Chom.2007.06.003  0.502
2007 Stuchell-Brereton MD, Skalicky JJ, Kieffer C, Karren MA, Ghaffarian S, Sundquist WI. ESCRT-III recognition by VPS4 ATPases. Nature. 449: 740-4. PMID 17928862 DOI: 10.1038/Nature06172  0.542
2007 Sundquist WI, Hill CP. How to assemble a capsid. Cell. 131: 17-9. PMID 17923081 DOI: 10.1016/J.Cell.2007.09.028  0.421
2007 Morita E, Sandrin V, Chung HY, Morham SG, Gygi SP, Rodesch CK, Sundquist WI. Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. The Embo Journal. 26: 4215-27. PMID 17853893 DOI: 10.1038/Sj.Emboj.7601850  0.512
2007 Kelly BN, Kyere S, Kinde I, Tang C, Howard BR, Robinson H, Sundquist WI, Summers MF, Hill CP. Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein. Journal of Molecular Biology. 373: 355-66. PMID 17826792 DOI: 10.1016/J.Jmb.2007.07.070  0.521
2007 Alam SL, Sundquist WI. Structural biology: ESCRT service. Nature. 447: 921-2. PMID 17581573 DOI: 10.1038/447921A  0.35
2007 De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, Kaplan J. The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Molecular Biology of the Cell. 18: 2569-78. PMID 17475779 DOI: 10.1091/Mbc.E07-01-0060  0.352
2007 Higa MM, Alam SL, Sundquist WI, Ullman KS. Molecular characterization of the Ran-binding zinc finger domain of Nup153. The Journal of Biological Chemistry. 282: 17090-100. PMID 17426026 DOI: 10.1074/Jbc.M702715200  0.408
2007 Wright ER, Schooler JB, Ding HJ, Kieffer C, Fillmore C, Sundquist WI, Jensen GJ. Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells. The Embo Journal. 26: 2218-26. PMID 17396149 DOI: 10.1038/Sj.Emboj.7601664  0.465
2007 Fisher RD, Chung HY, Zhai Q, Robinson H, Sundquist WI, Hill CP. Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding. Cell. 128: 841-52. PMID 17350572 DOI: 10.1016/J.Cell.2007.01.035  0.559
2007 Wright E, Schooler J, Ding H, Kieffer C, Fillmore C, Sundquist W, Jensen G. Electron Cryotomography of HIV-1 Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607076738  0.367
2006 Arrigoni R, Alam SL, Wamstad JA, Bardwell VJ, Sundquist WI, Schreiber-Agus N. The Polycomb-associated protein Rybp is a ubiquitin binding protein. Febs Letters. 580: 6233-41. PMID 17070805 DOI: 10.1016/J.Febslet.2006.10.027  0.431
2006 Alam SL, Langelier C, Whitby FG, Koirala S, Robinson H, Hill CP, Sundquist WI. Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nature Structural & Molecular Biology. 13: 1029-30. PMID 17057716 DOI: 10.1038/Nsmb1160  0.45
2006 Kelly BN, Howard BR, Wang H, Robinson H, Sundquist WI, Hill CP. Implications for viral capsid assembly from crystal structures of HIV-1 Gag(1-278) and CA(N)(133-278). Biochemistry. 45: 11257-66. PMID 16981686 DOI: 10.1021/Bi060927X  0.549
2006 Langelier C, von Schwedler UK, Fisher RD, De Domenico I, White PL, Hill CP, Kaplan J, Ward D, Sundquist WI. Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. Journal of Virology. 80: 9465-80. PMID 16973552 DOI: 10.1128/Jvi.01049-06  0.467
2006 Stremlau M, Perron M, Lee M, Li Y, Song B, Javanbakht H, Diaz-Griffero F, Anderson DJ, Sundquist WI, Sodroski J. Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor. Proceedings of the National Academy of Sciences of the United States of America. 103: 5514-9. PMID 16540544 DOI: 10.1073/Pnas.0509996103  0.481
2006 Arrigoni R, Alam SL, Wamstad JA, Bardwell VJ, Sundquist WI, Schreiber-Agus N. Corrigendum to "The Polycomb-associated protein Rybp is a ubiquitin binding protein" [FEBS Lett. 580 (2006) 6233-6241] (DOI:10.1016/j.febslet.2006.10.027) Febs Letters. 580: 6754. DOI: 10.1016/J.Febslet.2006.11.022  0.408
2005 Scott A, Chung HY, Gonciarz-Swiatek M, Hill GC, Whitby FG, Gaspar J, Holton JM, Viswanathan R, Ghaffarian S, Hill CP, Sundquist WI. Structural and mechanistic studies of VPS4 proteins. The Embo Journal. 24: 3658-69. PMID 16193069 DOI: 10.1038/Sj.Emboj.7600818  0.558
2005 Scott A, Gaspar J, Stuchell-Brereton MD, Alam SL, Skalicky JJ, Sundquist WI. Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A. Proceedings of the National Academy of Sciences of the United States of America. 102: 13813-8. PMID 16174732 DOI: 10.1073/Pnas.0502165102  0.568
2005 Schmitt AP, Leser GP, Morita E, Sundquist WI, Lamb RA. Evidence for a new viral late-domain core sequence, FPIV, necessary for budding of a paramyxovirus. Journal of Virology. 79: 2988-97. PMID 15709019 DOI: 10.1128/Jvi.79.5.2988-2997.2005  0.483
2005 Benjamin J, Ganser-Pornillos BK, Tivol WF, Sundquist WI, Jensen GJ. Three-dimensional structure of HIV-1 virus-like particles by electron cryotomography. Journal of Molecular Biology. 346: 577-88. PMID 15670606 DOI: 10.1016/J.Jmb.2004.11.064  0.483
2005 Ward DM, Vaughn MB, Shiflett SL, White PL, Pollock AL, Hill J, Schnegelberger R, Sundquist WI, Kaplan J. The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. The Journal of Biological Chemistry. 280: 10548-55. PMID 15644320 DOI: 10.1074/Jbc.M413734200  0.485
2004 Morita E, Sundquist WI. Retrovirus budding. Annual Review of Cell and Developmental Biology. 20: 395-425. PMID 15473846 DOI: 10.1146/annurev.cellbio.20.010403.102350  0.316
2004 Stuchell MD, Garrus JE, Müller B, Stray KM, Ghaffarian S, McKinnon R, Kräusslich HG, Morham SG, Sundquist WI. The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. The Journal of Biological Chemistry. 279: 36059-71. PMID 15218037 DOI: 10.1074/Jbc.M405226200  0.569
2004 Hatziioannou T, Cowan S, Von Schwedler UK, Sundquist WI, Bieniasz PD. Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid. Journal of Virology. 78: 6005-12. PMID 15140998 DOI: 10.1128/Jvi.78.11.6005-6012.2004  0.473
2004 Sundquist WI, Schubert HL, Kelly BN, Hill GC, Holton JM, Hill CP. Ubiquitin recognition by the human TSG101 protein. Molecular Cell. 13: 783-9. PMID 15053872 DOI: 10.1016/S1097-2765(04)00129-7  0.546
2004 Alam SL, Sun J, Payne M, Welch BD, Blake BK, Davis DR, Meyer HH, Emr SD, Sundquist WI. Ubiquitin interactions of NZF zinc fingers. The Embo Journal. 23: 1411-21. PMID 15029239 DOI: 10.1038/Sj.Emboj.7600114  0.506
2004 Ganser-Pornillos BK, von Schwedler UK, Stray KM, Aiken C, Sundquist WI. Assembly properties of the human immunodeficiency virus type 1 CA protein. Journal of Virology. 78: 2545-52. PMID 14963157 DOI: 10.1128/Jvi.78.5.2545-2552.2004  0.444
2003 von Schwedler UK, Stuchell M, Müller B, Ward DM, Chung HY, Morita E, Wang HE, Davis T, He GP, Cimbora DM, Scott A, Kräusslich HG, Kaplan J, Morham SG, Sundquist WI. The protein network of HIV budding. Cell. 114: 701-13. PMID 14505570 DOI: 10.1016/S0092-8674(03)00714-1  0.497
2003 Pornillos O, Higginson DS, Stray KM, Fisher RD, Garrus JE, Payne M, He GP, Wang HE, Morham SG, Sundquist WI. HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. The Journal of Cell Biology. 162: 425-34. PMID 12900394 DOI: 10.1083/Jcb.200302138  0.782
2003 Gu Y, Sundquist WI. Good to CU. Nature. 424: 21-2. PMID 12840737 DOI: 10.1038/424021A  0.396
2003 Ganser BK, Cheng A, Sundquist WI, Yeager M. Three-dimensional structure of the M-MuLV CA protein on a lipid monolayer: a general model for retroviral capsid assembly. The Embo Journal. 22: 2886-92. PMID 12805204 DOI: 10.1093/Emboj/Cdg276  0.785
2003 Fisher RD, Wang B, Alam SL, Higginson DS, Robinson H, Sundquist WI, Hill CP. Structure and ubiquitin binding of the ubiquitin-interacting motif. The Journal of Biological Chemistry. 278: 28976-84. PMID 12750381 DOI: 10.1074/Jbc.M302596200  0.47
2003 Howard BR, Vajdos FF, Li S, Sundquist WI, Hill CP. Structural insights into the catalytic mechanism of cyclophilin A. Nature Structural Biology. 10: 475-81. PMID 12730686 DOI: 10.1038/Nsb927  0.477
2003 von Schwedler UK, Stray KM, Garrus JE, Sundquist WI. Functional surfaces of the human immunodeficiency virus type 1 capsid protein. Journal of Virology. 77: 5439-50. PMID 12692245 DOI: 10.1128/Jvi.77.9.5439-5450.2003  0.435
2003 Wang B, Alam SL, Meyer HH, Payne M, Stemmler TL, Davis DR, Sundquist WI. Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4. The Journal of Biological Chemistry. 278: 20225-34. PMID 12644454 DOI: 10.1074/Jbc.M300459200  0.504
2002 Pornillos O, Garrus JE, Sundquist WI. Mechanisms of enveloped RNA virus budding. Trends in Cell Biology. 12: 569-79. PMID 12495845 DOI: 10.1016/S0962-8924(02)02402-9  0.688
2002 Pornillos O, Alam SL, Davis DR, Sundquist WI. Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein. Nature Structural Biology. 9: 812-7. PMID 12379843 DOI: 10.1038/Nsb856  0.775
2002 Pornillos O, Alam SL, Rich RL, Myszka DG, Davis DR, Sundquist WI. Structure and functional interactions of the Tsg101 UEV domain. The Embo Journal. 21: 2397-406. PMID 12006492 DOI: 10.1093/Emboj/21.10.2397  0.763
2002 Forshey BM, von Schwedler U, Sundquist WI, Aiken C. Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication. Journal of Virology. 76: 5667-77. PMID 11991995 DOI: 10.1128/Jvi.76.11.5667-5677.2002  0.49
2002 Bosco DA, Eisenmesser EZ, Pochapsky S, Sundquist WI, Kern D. Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A. Proceedings of the National Academy of Sciences of the United States of America. 99: 5247-52. PMID 11929983 DOI: 10.1073/Pnas.082100499  0.448
2001 Garrus JE, von Schwedler UK, Pornillos OW, Morham SG, Zavitz KH, Wang HE, Wettstein DA, Stray KM, Côté M, Rich RL, Myszka DG, Sundquist WI. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell. 107: 55-65. PMID 11595185 DOI: 10.1016/S0092-8674(01)00506-2  0.769
2001 Jenkins Y, Pornillos O, Rich RL, Myszka DG, Sundquist WI, Malim MH. Biochemical analyses of the interactions between human immunodeficiency virus type 1 Vpr and p6(Gag). Journal of Virology. 75: 10537-42. PMID 11581428 DOI: 10.1128/Jvi.75.21.10537-10542.2001  0.733
2000 Li S, Hill CP, Sundquist WI, Finch JT. Image reconstructions of helical assemblies of the HIV-1 CA protein Nature. 407: 409-413. PMID 11014200 DOI: 10.1038/35030177  0.491
2000 Von Schwedler UK, Stemmler TL, Klishko VY, Li S, Albertine KH, Davis DR, Sundquist WI. Corrigendum: Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly (The EMBO Journal (1998) 17, (1555-1568)) Embo Journal. 19: 2391.  0.426
1999 Worthylake DK, Wang H, Yoo S, Sundquist WI, Hill CP. Structures of the HIV-1 capsid protein dimerization domain at 2.6 Å resolution Acta Crystallographica Section D: Biological Crystallography. 55: 85-92. PMID 10089398 DOI: 10.1107/S0907444998007689  0.521
1999 Ganser BK, Li S, Klishko VY, Finch JT, Sundquist WI. Assembly and analysis of conical models for the HIV-1 core. Science (New York, N.Y.). 283: 80-3. PMID 9872746 DOI: 10.1126/Science.283.5398.80  0.797
1998 von Schwedler UK, Stemmler TL, Klishko VY, Li S, Albertine KH, Davis DR, Sundquist WI. Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly. The Embo Journal. 17: 1555-68. PMID 9501077 DOI: 10.1093/Emboj/17.6.1555  0.517
1997 Vajdos FF, Yoo S, Houseweart M, Sundquist WI, Hill CP. Crystal structure of cyclophilin a complexed with a binding site peptide from the HIV-1 capsid protein Protein Science. 6: 2297-2307. PMID 9385632 DOI: 10.1002/Pro.5560061103  0.491
1997 Gamble TR, Yoo S, Vajdos FF, von Schwedler UK, Worthylake DK, Wang H, McCutcheon JP, Sundquist WI, Hill CP. Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein. Science (New York, N.Y.). 278: 849-53. PMID 9346481 DOI: 10.1126/Science.278.5339.849  0.561
1997 Yoo S, Myszka DG, Yeh Cy, McMurray M, Hill CP, Sundquist WI. Molecular recognition in the HIV-1 Capsid/Cyclophilin A complex Journal of Molecular Biology. 269: 780-795. PMID 9223641 DOI: 10.1006/Jmbi.1997.1051  0.517
1996 Christensen AM, Massiah MA, Turner BG, Sundquist WI, Summers MF. Three-dimensional structure of the HTLV-II matrix protein and comparative analysis of matrix proteins from the different classes of pathogenic human retroviruses. Journal of Molecular Biology. 264: 1117-31. PMID 9000634 DOI: 10.1006/Jmbi.1996.0700  0.457
1996 Gamble TR, Vajdos FF, Yoo S, Worthylake DK, Houseweart M, Sundquist WI, Hill CP. Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid Cell. 87: 1285-1294. PMID 8980234 DOI: 10.1016/S0092-8674(00)81823-1  0.573
1996 Massiah MA, Worthylake D, Christensen AM, Sundquist WI, Hill CP, Summers MF. Comparison of the NMR and X-ray structures of the HIV-1 matrix protein: evidence for conformational changes during viral assembly. Protein Science : a Publication of the Protein Society. 5: 2391-8. PMID 8976548 DOI: 10.1002/Pro.5560051202  0.43
1996 Gitti RK, Lee BM, Walker J, Summers MF, Yoo S, Sundquist WI. Structure of the amino-terminal core domain of the HIV-1 capsid protein. Science (New York, N.Y.). 273: 231-5. PMID 8662505 DOI: 10.1126/Science.273.5272.231  0.555
1996 Hill CP, Worthylake D, Bancroft DP, Christensen AM, Sundquist WI. Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: Implications for membrane association and assembly Proceedings of the National Academy of Sciences of the United States of America. 93: 3099-3104. PMID 8610175 DOI: 10.1073/Pnas.93.7.3099  0.498
1994 Massiah MA, Starich MR, Paschall C, Summers MF, Christensen AM, Sundquist WI. Three-dimensional structure of the human immunodeficiency virus type 1 matrix protein. Journal of Molecular Biology. 244: 198-223. PMID 7966331 DOI: 10.1006/Jmbi.1994.1719  0.52
1993 Sundquist WI, Heaphy S. Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA Proceedings of the National Academy of Sciences of the United States of America. 90: 3393-3397. PMID 8475087 DOI: 10.1073/Pnas.90.8.3393  0.389
1989 Sundquist WI, Klug A. Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops. Nature. 342: 825-9. PMID 2601741 DOI: 10.1038/342825A0  0.539
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