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Tharan Srikumar, Ph.D. - Publications

Affiliations: 
2013 University of Toronto, Toronto, ON, Canada 
Area:
Biomechanics Biophysics
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Costanzo M, VanderSluis B, Koch EN, Baryshnikova A, Pons C, Tan G, Wang W, Usaj M, Hanchard J, Lee SD, Pelechano V, Styles EB, Billmann M, van Leeuwen J, van Dyk N, ... ... Srikumar T, et al. A global genetic interaction network maps a wiring diagram of cellular function. Science (New York, N.Y.). 353. PMID 27708008 DOI: 10.1126/Science.Aaf1420  0.558
2016 Guturi KK, Bohgaki M, Bohgaki T, Srikumar T, Ng D, Kumareswaran R, El Ghamrasni S, Jeon J, Patel P, Eldin MS, Bristow R, Cheung P, Stewart GS, Raught B, Hakem A, et al. RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation. Nature Communications. 7: 12638. PMID 27558965 DOI: 10.1038/Ncomms12638  0.569
2016 Heir P, Srikumar T, Bikopoulos G, Bunda S, Poon BP, Lee JE, Raught B, Ohh M. Oxygen-Dependent Regulation of Erythropoietin Receptor Turnover And Signaling. The Journal of Biological Chemistry. PMID 26846855 DOI: 10.1074/Jbc.M115.694562  0.558
2015 Srikumar T, Lewicki MC, Raught B. Raw data for the identification of SUMOylated proteins in S. cerevisiae subjected to two types of osmotic shock, using affinity purification coupled with mass spectrometry. Data in Brief. 2: 29-31. PMID 26217701 DOI: 10.1016/J.Dib.2014.11.003  0.581
2015 Hong JH, Ng D, Srikumar T, Raught B. The use of ubiquitin lysine mutants to characterize E2-E3 linkage specificity: Mass spectrometry offers a cautionary "tail". Proteomics. PMID 26036340 DOI: 10.1002/Pmic.201500058  0.594
2015 Matsuzaki S, Lee L, Knock E, Srikumar T, Sakurai M, Hazrati LN, Katayama T, Staniszewski A, Raught B, Arancio O, Fraser PE. SUMO1 Affects Synaptic Function, Spine Density and Memory. Scientific Reports. 5: 10730. PMID 26022678 DOI: 10.1038/Srep10730  0.549
2015 Hong JH, Kaustov L, Coyaud E, Srikumar T, Wan J, Arrowsmith C, Raught B. KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation. Molecular & Cellular Proteomics : McP. 14: 674-85. PMID 25582440 DOI: 10.1074/Mcp.M114.042168  0.62
2015 Dingar D, Kalkat M, Chan PK, Srikumar T, Bailey SD, Tu WB, Coyaud E, Ponzielli R, Kolyar M, Jurisica I, Huang A, Lupien M, Penn LZ, Raught B. BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors. Journal of Proteomics. 118: 95-111. PMID 25452129 DOI: 10.1016/J.Jprot.2014.09.029  0.622
2015 Lewicki MC, Srikumar T, Johnson E, Raught B. The S. cerevisiae SUMO stress response is a conjugation-deconjugation cycle that targets the transcription machinery. Journal of Proteomics. 118: 39-48. PMID 25434491 DOI: 10.1016/J.Jprot.2014.11.012  0.595
2015 Cubeñas-Potts C, Srikumar T, Lee C, Osula O, Subramonian D, Zhang XD, Cotter RJ, Raught B, Matunis MJ. Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes. Proteomics. 15: 763-72. PMID 25367092 DOI: 10.1002/Pmic.201400400  0.598
2015 Dingar D, Kalkat M, Chan P, Bailey SD, Srikumar T, Tu WB, Coyaud E, Ponzielli R, Kolyar M, Jurisica I, Huang A, Lupien M, Raught B, Penn LZ. Abstract B04: In vivo BioID identifies novel Myc interacting partners Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-B04  0.63
2015 Resetca D, Kalkat M, Lourenco C, Chan P, Srikumar T, Raught B, Penn L. Abstract A12: Identifying MYC post-translational modifications using a mass spectrometry-based approach Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-A12  0.615
2015 Kalkat M, Chan P, Wasylishen AR, Srikumar T, Kim SS, Ponzielli R, Bazett-Jones DP, Raught B, Penn LZ. Abstract A08: Identification of c-MYC SUMOylation by mass spectrometry Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-A08  0.631
2014 Chan PK, Srikumar T, Dingar D, Kalkat M, Penn LZ, Raught B. BioID data of c-MYC interacting protein partners in cultured cells and xenograft tumors. Data in Brief. 1: 76-8. PMID 26217692 DOI: 10.1016/J.Dib.2014.10.001  0.572
2014 Kalkat M, Chan PK, Wasylishen AR, Srikumar T, Kim SS, Ponzielli R, Bazett-Jones DP, Raught B, Penn LZ. Identification of c-MYC SUMOylation by mass spectrometry. Plos One. 9: e115337. PMID 25522242 DOI: 10.1371/Journal.Pone.0115337  0.593
2014 Bunda S, Heir P, Srikumar T, Cook JD, Burrell K, Kano Y, Lee JE, Zadeh G, Raught B, Ohh M. Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 111: E3785-94. PMID 25157176 DOI: 10.1073/Pnas.1406559111  0.514
2013 Singer AU, Schulze S, Skarina T, Xu X, Cui H, Eschen-Lippold L, Egler M, Srikumar T, Raught B, Lee J, Scheel D, Savchenko A, Bonas U. Correction: A Pathogen Type III Effector with a Novel E3 Ubiquitin Ligase Architecture. Plos Pathogens. 9. PMID 29294480 DOI: 10.1371/Annotation/8C6Eaae4-72A7-460A-8B1A-F855731F3706  0.528
2013 Bohgaki M, Bohgaki T, El Ghamrasni S, Srikumar T, Maire G, Panier S, Fradet-Turcotte A, Stewart GS, Raught B, Hakem A, Hakem R. RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks. Proceedings of the National Academy of Sciences of the United States of America. 110: 20982-7. PMID 24324146 DOI: 10.1073/Pnas.1320302111  0.543
2013 Bassi C, Ho J, Srikumar T, Dowling RJ, Gorrini C, Miller SJ, Mak TW, Neel BG, Raught B, Stambolic V. Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress. Science (New York, N.Y.). 341: 395-9. PMID 23888040 DOI: 10.1126/Science.1236188  0.567
2013 Srikumar T, Lewicki MC, Raught B. A global S. cerevisiae small ubiquitin-related modifier (SUMO) system interactome. Molecular Systems Biology. 9: 668. PMID 23712011 DOI: 10.1038/Msb.2013.23  0.632
2013 Rivkin E, Almeida SM, Ceccarelli DF, Juang YC, MacLean TA, Srikumar T, Huang H, Dunham WH, Fukumura R, Xie G, Gondo Y, Raught B, Gingras AC, Sicheri F, Cordes SP. The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature. 498: 318-24. PMID 23708998 DOI: 10.1038/Nature12296  0.587
2013 Srikumar T, Lewicki MC, Costanzo M, Tkach JM, van Bakel H, Tsui K, Johnson ES, Brown GW, Andrews BJ, Boone C, Giaever G, Nislow C, Raught B. Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. The Journal of Cell Biology. 201: 145-63. PMID 23547032 DOI: 10.1083/Jcb.201210019  0.609
2013 Singer AU, Schulze S, Skarina T, Xu X, Cui H, Eschen-Lippold L, Egler M, Srikumar T, Raught B, Lee J, Scheel D, Savchenko A, Bonas U. A pathogen type III effector with a novel E3 ubiquitin ligase architecture. Plos Pathogens. 9: e1003121. PMID 23359647 DOI: 10.1371/Journal.Ppat.1003121  0.587
2013 Rivkin E, Almeida SM, Ceccarelli DF, Juang Y-, MacLean TA, Srikumar T, Huang H, Dunham W, Fukumura R, Xie G, Gondo Y, Raught B, Gingras A-, Sicheri F, Cordes S. The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesisThe linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis Nature. DOI: 10.2210/Pdb4Ksj/Pdb  0.554
2012 Liu G, Zhang J, Choi H, Lambert JP, Srikumar T, Larsen B, Nesvizhskii AI, Raught B, Tyers M, Gingras AC. Using ProHits to store, annotate, and analyze affinity purification-mass spectrometry (AP-MS) data. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit8.16. PMID 22948730 DOI: 10.1002/0471250953.Bi0816S39  0.552
2012 Sheng Y, Hong JH, Doherty R, Srikumar T, Shloush J, Avvakumov GV, Walker JR, Xue S, Neculai D, Wan JW, Kim SK, Arrowsmith CH, Raught B, Dhe-Paganon S. A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Molecular & Cellular Proteomics : McP. 11: 329-41. PMID 22496338 DOI: 10.1074/Mcp.O111.013706  0.577
2011 Fabian MR, Cieplak MK, Frank F, Morita M, Green J, Srikumar T, Nagar B, Yamamoto T, Raught B, Duchaine TF, Sonenberg N. miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. Nature Structural & Molecular Biology. 18: 1211-7. PMID 21984185 DOI: 10.1038/Nsmb.2149  0.618
2011 Békés M, Prudden J, Srikumar T, Raught B, Boddy MN, Salvesen GS. The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteases. The Journal of Biological Chemistry. 286: 10238-47. PMID 21247896 DOI: 10.1074/Jbc.M110.205153  0.551
2010 Sydorskyy Y, Srikumar T, Jeram SM, Wheaton S, Vizeacoumar FJ, Makhnevych T, Chong YT, Gingras AC, Raught B. A novel mechanism for SUMO system control: regulated Ulp1 nucleolar sequestration. Molecular and Cellular Biology. 30: 4452-62. PMID 20647537 DOI: 10.1128/Mcb.00335-10  0.577
2010 Jeram SM, Srikumar T, Zhang XD, Anne Eisenhauer H, Rogers R, Pedrioli PG, Matunis M, Raught B. An improved SUMmOn-based methodology for the identification of ubiquitin and ubiquitin-like protein conjugation sites identifies novel ubiquitin-like protein chain linkages. Proteomics. 10: 254-65. PMID 20029837 DOI: 10.1002/Pmic.200900648  0.604
2010 Srikumar T, Jeram SM, Lam H, Raught B. A ubiquitin and ubiquitin-like protein spectral library. Proteomics. 10: 337-42. PMID 19899083 DOI: 10.1002/Pmic.200900627  0.6
2009 Jeram SM, Srikumar T, Pedrioli PG, Raught B. Using mass spectrometry to identify ubiquitin and ubiquitin-like protein conjugation sites. Proteomics. 9: 922-34. PMID 19180541 DOI: 10.1002/Pmic.200800666  0.637
2009 Makhnevych T, Sydorskyy Y, Xin X, Srikumar T, Vizeacoumar FJ, Jeram SM, Li Z, Bahr S, Andrews BJ, Boone C, Raught B. Global map of SUMO function revealed by protein-protein interaction and genetic networks. Molecular Cell. 33: 124-35. PMID 19150434 DOI: 10.1016/J.Molcel.2008.12.025  0.591
2008 McCluskey AJ, Poon GMK, Bolewska-Pedyczak E, Srikumar T, Jeram SM, Raught B, Gariépy J. The Catalytic Subunit of Shiga-like Toxin 1 Interacts with Ribosomal Stalk Proteins and is Inhibited by Their Conserved C-Terminal Domain Journal of Molecular Biology. 378: 375-386. PMID 18358491 DOI: 10.1016/J.Jmb.2008.02.014  0.595
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