| Year |
Citation |
Score |
| 2023 |
Proffitt MR, Liu X, Ortlund EA, Smith GT. Evolution of androgen receptors contributes to species variation in androgenic regulation of communication signals in electric fishes. Molecular and Cellular Endocrinology. 112068. PMID 37714403 DOI: 10.1016/j.mce.2023.112068 |
0.308 |
|
| 2023 |
Mays SG, Hercules D, Ortlund EA, Okafor CD. The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits. Protein Science : a Publication of the Protein Society. e4754. PMID 37572334 DOI: 10.1002/pro.4754 |
0.657 |
|
| 2023 |
Cato ML, D'Agostino EH, Spurlin RM, Flynn AR, Cornelison JL, Johnson AM, Fujita RA, Abraham SM, Jui NT, Ortlund EA. Comparison of Activity, Structure, and Dynamics of SF-1 and LRH-1 Complexed with Small Molecule Modulators. The Journal of Biological Chemistry. 104921. PMID 37328104 DOI: 10.1016/j.jbc.2023.104921 |
0.395 |
|
| 2023 |
Mays SG, Hercules D, Ortlund EA, Okafor CD. The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits. Biorxiv : the Preprint Server For Biology. PMID 36747705 DOI: 10.1101/2023.01.27.525934 |
0.655 |
|
| 2022 |
Cato ML, Cornelison JL, Spurlin RM, Courouble VV, Patel AB, Flynn AR, Johnson AM, Okafor CD, Frank F, D'Agostino EH, Griffin PR, Jui NT, Ortlund EA. Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket. Journal of Medicinal Chemistry. PMID 35503419 DOI: 10.1021/acs.jmedchem.2c00235 |
0.668 |
|
| 2022 |
Mays SG, D'Agostino EH, Flynn AR, Huang X, Wang G, Liu X, Millings EJ, Okafor CD, Patel A, Cato ML, Cornelison JL, Melchers D, Houtman R, Moore DD, Calvert JW, ... ... Ortlund EA, et al. A phospholipid mimetic targeting LRH-1 ameliorates colitis. Cell Chemical Biology. PMID 35316658 DOI: 10.1016/j.chembiol.2022.03.001 |
0.675 |
|
| 2021 |
Frank F, Ortlund EA, Liu X. Structural insights into glucocorticoid receptor function. Biochemical Society Transactions. PMID 34709368 DOI: 10.1042/BST20210419 |
0.317 |
|
| 2021 |
Frank F, Liu X, Ortlund EA. Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34285072 DOI: 10.1073/pnas.2024685118 |
0.359 |
|
| 2021 |
Bruno NE, Nwachukwu JC, Srinivasan S, Nettles CC, Izard T, Jin Z, Nowak J, Cameron MD, Boregowda SV, Phinney DG, Elemento O, Liu X, Ortlund EA, Houtman R, Stavreva DA, et al. Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling. Nature Chemical Biology. PMID 33510451 DOI: 10.1038/s41589-020-00719-w |
0.339 |
|
| 2020 |
Mays SG, Stec J, Liu X, D'Agostino EH, Whitby RJ, Ortlund EA. Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist. Scientific Reports. 10: 22279. PMID 33335203 DOI: 10.1038/s41598-020-79251-9 |
0.378 |
|
| 2020 |
Moody JC, Qadota H, Reedy AR, Okafor CD, Shanmugan N, Matsunaga Y, Christian CJ, Ortlund EA, Benian GM. The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells. Nature Communications. 11: 5010. PMID 33024114 DOI: 10.1038/s41467-020-18852-4 |
0.522 |
|
| 2020 |
Liu X, Wang Y, Gutierrez JS, Damsker JM, Nagaraju K, Hoffman EP, Ortlund EA. Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. Proceedings of the National Academy of Sciences of the United States of America. PMID 32917814 DOI: 10.1073/Pnas.2006890117 |
0.408 |
|
| 2020 |
Tillman MC, Imai N, Li Y, Khadka M, Okafor CD, Juneja P, Adhiyaman A, Hagen SJ, Cohen DE, Ortlund EA. Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine. Proceedings of the National Academy of Sciences of the United States of America. PMID 32820071 DOI: 10.1073/Pnas.2003877117 |
0.611 |
|
| 2020 |
Frank F, Kavousi N, Bountali A, Dammer EB, Mourtada-Maarabouni M, Ortlund EA. The lncRNA Growth Arrest Specific 5 Regulates Cell Survival via Distinct Structural Modules with Independent Functions. Cell Reports. 32: 107933. PMID 32697996 DOI: 10.1016/J.Celrep.2020.107933 |
0.336 |
|
| 2020 |
Cornelison JL, Cato ML, Johnson AM, D'Agostino EH, Melchers D, Patel AB, Mays SG, Houtman R, Ortlund EA, Jui NT. Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition. Bioorganic & Medicinal Chemistry Letters. 30: 127293. PMID 32631515 DOI: 10.1016/J.Bmcl.2020.127293 |
0.485 |
|
| 2020 |
D'Agostino EH, Flynn AR, Cornelison JL, Mays SG, Patel A, Jui NT, Ortlund EA. Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear Receptors. Acs Medicinal Chemistry Letters. 11: 365-370. PMID 32184971 DOI: 10.1021/Acsmedchemlett.9B00442 |
0.489 |
|
| 2020 |
Druzak SA, Mays S, Ortlund E. SAT-LB124 Phosphatidylcholine Transfer Protein Interacts With PPARδ to Modulate Activity Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2334 |
0.401 |
|
| 2020 |
Frank F, Kavousi N, Bountali A, Dammer E, Mourtada-Maarabouni M, Ortlund E. SAT-LB138 The LncRNA Growth Arrest Specific 5 Regulates Cell Survival via Distinct Structural Modules With Independent Functions Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2327 |
0.366 |
|
| 2020 |
Tillman MC, Li Y, Khadka MC, Imai N, Adhiyaman AC, Juneja PC, Hagen SJ, Cohen DE, Ortlund EA. Them1 Binds to Free Fatty Acids and is Allosterically Regulated by Lysophosphatidylcholine to Control Fatty Acyl‐CoA Hydrolysis in Brown Adipose Tissue The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07311 |
0.328 |
|
| 2020 |
Baqai M, Li Y, Tillman M, Ortlund EA, Cohen DE, Hagen SJ. The Them1 START Domain Regulates Nuclear Trafficking in Brown Adipocytes The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04590 |
0.302 |
|
| 2020 |
Cato ML, Cornelison J, Flynn A, D’Agostino E, Jui N, Ortlund E. Development of picomolar liver receptor homolog‐1 agonist The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02884 |
0.352 |
|
| 2019 |
Okafor CD, Hercules D, Kell SA, Ortlund EA. Rewiring Ancient Residue Interaction Networks Drove the Evolution of Specificity in Steroid Receptors. Structure (London, England : 1993). PMID 31831214 DOI: 10.1016/J.Str.2019.11.012 |
0.645 |
|
| 2019 |
Mays S, Flynn AR, Cornelison J, Okafor CD, Wang H, Wang G, Huang X, Donaldson H, Millings E, Polavarapu R, Moore D, Calvert J, Jui NT, Ortlund EA. Development of the first low nanomolar Liver Receptor Homolog-1 agonist through structure-guided design. Journal of Medicinal Chemistry. PMID 31419141 DOI: 10.1021/Acs.Jmedchem.9B00753 |
0.667 |
|
| 2019 |
Liu X, Wang Y, Ortlund EA. First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-PGC1lower case Greek alpha Complex with Endogenous and Synthetic Glucocorticoids. Molecular Pharmacology. PMID 31391291 DOI: 10.1124/Mol.119.116806 |
0.513 |
|
| 2019 |
Tillman MC, Khadka M, Duffy J, Wang MC, Ortlund EA. Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8. Scientific Reports. 9: 9966. PMID 31292465 DOI: 10.1038/S41598-019-46230-8 |
0.476 |
|
| 2019 |
Okafor CD, Colucci JK, Ortlund EA. Ligand-Induced Allosteric Effects Governing SR Signaling Nuclear Receptor Research. 6. DOI: 10.32527/2019/101382 |
0.709 |
|
| 2018 |
Flynn AR, Mays SG, Ortlund EA, Jui NT. Development of Hybrid Phospholipid Mimics as Effective Agonists for Liver Receptor Homologue-1. Acs Medicinal Chemistry Letters. 9: 1051-1056. PMID 30344916 DOI: 10.1021/Acsmedchemlett.8B00361 |
0.464 |
|
| 2018 |
Frank F, Okafor CD, Ortlund EA. The first crystal structure of a DNA-free nuclear receptor DNA binding domain sheds light on DNA-driven allostery in the glucocorticoid receptor. Scientific Reports. 8: 13497. PMID 30201977 DOI: 10.1038/S41598-018-31812-9 |
0.663 |
|
| 2018 |
Weikum ER, Liu X, Ortlund EA. The nuclear receptor superfamily: A structural perspective. Protein Science : a Publication of the Protein Society. PMID 30109749 DOI: 10.1002/Pro.3496 |
0.475 |
|
| 2018 |
Hudson WH, Vera IMS, Nwachukwu JC, Weikum ER, Herbst AG, Yang Q, Bain DL, Nettles KW, Kojetin DJ, Ortlund EA. Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements. Nature Communications. 9: 1337. PMID 29626214 DOI: 10.1038/S41467-018-03780-1 |
0.416 |
|
| 2018 |
Okafor CD, Pathak MC, Fagan CE, Bauer NC, Cole MF, Gaucher EA, Ortlund EA. Structural and Dynamics Comparison of Thermostability in Ancient, Modern, and Consensus Elongation Factor Tus. Structure (London, England : 1993). 26: 118-129.e3. PMID 29276038 DOI: 10.1016/J.Str.2017.11.018 |
0.604 |
|
| 2017 |
Weikum ER, de Vera IMS, Nwachukwu JC, Hudson WH, Nettles KW, Kojetin DJ, Ortlund EA. Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Nucleic Acids Research. PMID 28591827 DOI: 10.1093/Nar/Gkx509 |
0.456 |
|
| 2017 |
Weikum ER, Okafor DC, D'Agostino EH, Colucci JK, Ortlund EA. Structural analysis of the glucocorticoid receptor ligand-binding domain in complex with triamcinolone acetonide and a fragment of the atypical coregulator, SHP. Molecular Pharmacology. PMID 28396564 DOI: 10.1124/Mol.117.108506 |
0.536 |
|
| 2017 |
Mays SG, Okafor CD, Tuntland ML, Whitby RJ, Dharmarajan V, Stec J, Griffin PR, Ortlund EA. Structure and Dynamics of the Liver Receptor Homolog 1-PGC1α Complex. Molecular Pharmacology. PMID 28363985 DOI: 10.1124/Mol.117.108514 |
0.704 |
|
| 2017 |
Weikum ER, Knuesel MT, Ortlund EA, Yamamoto KR. Glucocorticoid receptor control of transcription: precision and plasticity via allostery. Nature Reviews. Molecular Cell Biology. PMID 28053348 DOI: 10.1038/Nrm.2016.152 |
0.409 |
|
| 2017 |
Mays SG, Okafor CD, Whitby RJ, Goswami D, Stec J, Flynn AR, Dugan MC, Jui NT, Griffin PR, Ortlund EA. Targeting the nuclear receptor LRH-1 with synthetic agonists Acta Crystallographica Section a Foundations and Advances. 73: a98-a98. DOI: 10.1107/S0108767317099020 |
0.62 |
|
| 2016 |
Weikum ER, Tuntland ML, Murphy MN, Ortlund EA. A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF) and Liver Receptor Homolog-1 (LRH-1). Journal of Molecular Biology. PMID 27984042 DOI: 10.1016/J.Jmb.2016.10.025 |
0.459 |
|
| 2016 |
Mays SG, Okafor CD, Whitby RJ, Goswami D, Stec JO, Flynn AR, Dugan MC, Jui NT, Griffin PR, Ortlund EA. Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists Reveal a Novel Mechanism of Activation. The Journal of Biological Chemistry. PMID 27694446 DOI: 10.1074/Jbc.M116.753541 |
0.718 |
|
| 2016 |
Musille PM, Kossmann BR, Kohn JA, Ivanov I, Ortlund EA. Unexpected Allosteric Network Contributes to LRH-1 Co-regulator Selectivity. The Journal of Biological Chemistry. 291: 1411-26. PMID 26553876 DOI: 10.1074/Jbc.M115.662874 |
0.533 |
|
| 2015 |
Hudson WH, Kossmann BR, de Vera IM, Chuo SW, Weikum ER, Eick GN, Thornton JW, Ivanov IN, Kojetin DJ, Ortlund EA. Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space. Proceedings of the National Academy of Sciences of the United States of America. PMID 26715749 DOI: 10.1073/Pnas.1518960113 |
0.468 |
|
| 2015 |
Yu K, Whitlock JM, Lee K, Ortlund EA, Yuan Cui Y, Hartzell HC. Identification of a lipid scrambling domain in ANO6/TMEM16F. Elife. 4. PMID 26057829 DOI: 10.7554/Elife.06901 |
0.301 |
|
| 2015 |
Brown NE, Goswami D, Branch MR, Ramineni S, Ortlund EA, Griffin PR, Hepler JR. Integration of G protein α (Gα) signaling by the regulator of G protein signaling 14 (RGS14). The Journal of Biological Chemistry. 290: 9037-49. PMID 25666614 DOI: 10.1074/Jbc.M114.634329 |
0.405 |
|
| 2015 |
Folick A, Oakley HD, Yu Y, Armstrong EH, Kumari M, Sanor L, Moore DD, Ortlund EA, Zechner R, Wang MC. Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans. Science (New York, N.Y.). 347: 83-6. PMID 25554789 DOI: 10.1126/Science.1258857 |
0.382 |
|
| 2014 |
Hudson WH, Pickard MR, de Vera IM, Kuiper EG, Mourtada-Maarabouni M, Conn GL, Kojetin DJ, Williams GT, Ortlund EA. Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate. Nature Communications. 5: 5395. PMID 25377354 DOI: 10.1038/Ncomms6395 |
0.389 |
|
| 2014 |
Hudson WH, Ortlund EA. The structure, function and evolution of proteins that bind DNA and RNA. Nature Reviews. Molecular Cell Biology. 15: 749-60. PMID 25269475 DOI: 10.1038/Nrm3884 |
0.37 |
|
| 2014 |
McKeown AN, Bridgham JT, Anderson DW, Murphy MN, Ortlund EA, Thornton JW. Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell. 159: 58-68. PMID 25259920 DOI: 10.1016/J.Cell.2014.09.003 |
0.422 |
|
| 2014 |
Hudson WH, Youn C, Ortlund EA. Crystal structure of the mineralocorticoid receptor DNA binding domain in complex with DNA. Plos One. 9: e107000. PMID 25188500 DOI: 10.1371/Journal.Pone.0107000 |
0.479 |
|
| 2014 |
Armstrong EH, Goswami D, Griffin PR, Noy N, Ortlund EA. Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway. The Journal of Biological Chemistry. 289: 14941-54. PMID 24692551 DOI: 10.1074/Jbc.M113.514646 |
0.425 |
|
| 2014 |
Musille P, Ortlund E. Structure of glycerol dehydrogenase from Serratia. Acta Crystallographica. Section F, Structural Biology Communications. 70: 166-72. PMID 24637749 DOI: 10.1107/S2053230X13034444 |
0.315 |
|
| 2014 |
Kratzer JT, Lanaspa MA, Murphy MN, Cicerchi C, Graves CL, Tipton PA, Ortlund EA, Johnson RJ, Gaucher EA. Evolutionary history and metabolic insights of ancient mammalian uricases Proceedings of the National Academy of Sciences of the United States of America. 111: 3763-3768. PMID 24550457 DOI: 10.1073/Pnas.1320393111 |
0.331 |
|
| 2014 |
Bridgham JT, Keay J, Ortlund EA, Thornton JW. Vestigialization of an allosteric switch: genetic and structural mechanisms for the evolution of constitutive activity in a steroid hormone receptor. Plos Genetics. 10: e1004058. PMID 24415950 DOI: 10.1371/Journal.Pgen.1004058 |
0.502 |
|
| 2014 |
Ren J, Pei-Chen Lin C, Pathak MC, Temple BR, Nile AH, Mousley CJ, Duncan MC, Eckert DM, Leiker TJ, Ivanova PT, Myers DS, Murphy RC, Brown HA, Verdaasdonk J, Bloom KS, ... Ortlund EA, et al. A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis. Molecular Biology of the Cell. 25: 712-27. PMID 24403601 DOI: 10.1091/Mbc.E13-11-0634 |
0.335 |
|
| 2014 |
Armstrong EH, Goswami D, Griffin PR, Noy N, Ortlund E. Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor beta / delta (FABP5-PPAR beta / delta ) signaling pathway. Journal of Biological Chemistry. 289: 14941-14954. DOI: 10.2210/Pdb4Lkp/Pdb |
0.417 |
|
| 2013 |
Colucci JK, Ortlund EA. X-ray crystal structure of the ancestral 3-ketosteroid receptor-progesterone-mifepristone complex shows mifepristone bound at the coactivator binding interface. Plos One. 8: e80761. PMID 24260475 DOI: 10.1371/Journal.Pone.0080761 |
0.548 |
|
| 2013 |
Colucci JK, Ortlund EA. Expression, purification and crystallization of the ancestral androgen receptor-DHT complex. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 994-6. PMID 23989146 DOI: 10.1107/S1744309113018745 |
0.478 |
|
| 2013 |
Harms MJ, Eick GN, Goswami D, Colucci JK, Griffin PR, Ortlund EA, Thornton JW. Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors. Proceedings of the National Academy of Sciences of the United States of America. 110: 11475-80. PMID 23798447 DOI: 10.1073/Pnas.1303930110 |
0.426 |
|
| 2013 |
Musille PM, Pathak M, Lauer JL, Griffin PR, Ortlund EA. Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors Journal of Biological Chemistry. 288: 20702-20712. PMID 23737522 DOI: 10.1074/Jbc.M113.472837 |
0.509 |
|
| 2013 |
Musille PM, Kohn JA, Ortlund EA. Phospholipid--driven gene regulation. Febs Letters. 587: 1238-46. PMID 23333623 DOI: 10.1016/J.Febslet.2013.01.004 |
0.354 |
|
| 2013 |
Hudson WH, Youn C, Ortlund EA. The structural basis of direct glucocorticoid-mediated transrepression. Nature Structural & Molecular Biology. 20: 53-8. PMID 23222642 DOI: 10.1038/Nsmb.2456 |
0.46 |
|
| 2012 |
Eick GN, Colucci JK, Harms MJ, Ortlund EA, Thornton JW. Evolution of minimal specificity and promiscuity in steroid hormone receptors. Plos Genetics. 8: e1003072. PMID 23166518 DOI: 10.1371/Journal.Pgen.1003072 |
0.49 |
|
| 2012 |
Rey J, Hu H, Kyle F, Lai CF, Buluwela L, Coombes RC, Ortlund EA, Ali S, Snyder JP, Barrett AG. Discovery of a new class of liver receptor homolog-1 (LRH-1) antagonists: virtual screening, synthesis and biological evaluation. Chemmedchem. 7: 1909-14. PMID 22961990 DOI: 10.1002/Cmdc.201200307 |
0.413 |
|
| 2012 |
Musille PM, Pathak MC, Lauer JL, Hudson WH, Griffin PR, Ortlund EA. Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation. Nature Structural & Molecular Biology. 19: 532-7, S1-2. PMID 22504882 DOI: 10.1038/Nsmb.2279 |
0.484 |
|
| 2012 |
Kohn JA, Deshpande K, Ortlund EA. Deciphering modern glucocorticoid cross-pharmacology using ancestral corticosteroid receptors. The Journal of Biological Chemistry. 287: 16267-75. PMID 22437833 DOI: 10.1074/Jbc.M112.346411 |
0.522 |
|
| 2012 |
Rey J, Hu H, Kyle F, Lai C, Buluwela L, Coombes RC, Ortlund EA, Ali S, Snyder JP, Barrett AGM. Back Cover: Discovery of a New Class of Liver Receptor Homolog-1 (LRH-1) Antagonists: Virtual Screening, Synthesis and Biological Evaluation (ChemMedChem 11/2012) Chemmedchem. 7: 2044-2044. DOI: 10.1002/Cmdc.201290058 |
0.325 |
|
| 2011 |
Ren J, Schaaf G, Bankaitis VA, Ortlund EA, Pathak MC. Crystallization and preliminary X-ray diffraction analysis of Sfh3, a member of the Sec14 protein superfamily. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1239-43. PMID 22102037 DOI: 10.1107/S1744309111027096 |
0.385 |
|
| 2011 |
Carroll SM, Ortlund EA, Thornton JW. Mechanisms for the evolution of a derived function in the ancestral glucocorticoid receptor. Plos Genetics. 7: e1002117. PMID 21698144 DOI: 10.1371/Journal.Pgen.1002117 |
0.41 |
|
| 2011 |
Lee JM, Lee YK, Mamrosh JL, Busby SA, Griffin PR, Pathak MC, Ortlund EA, Moore DD. A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature. 474: 506-10. PMID 21614002 DOI: 10.1038/Nature10111 |
0.394 |
|
| 2011 |
Schaaf G, Dynowski M, Mousley CJ, Shah SD, Yuan P, Winklbauer EM, de Campos MK, Trettin K, Quinones MC, Smirnova TI, Yanagisawa LL, Ortlund EA, Bankaitis VA. Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution. Molecular Biology of the Cell. 22: 892-905. PMID 21248202 DOI: 10.1091/Mbc.E10-11-0903 |
0.438 |
|
| 2011 |
Thiruchelvam PT, Lai CF, Hua H, Thomas RS, Hurtado A, Hudson W, Bayly AR, Kyle FJ, Periyasamy M, Photiou A, Spivey AC, Ortlund EA, Whitby RJ, Carroll JS, Coombes RC, et al. The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells. Breast Cancer Research and Treatment. 127: 385-96. PMID 20607599 DOI: 10.1007/S10549-010-0994-9 |
0.326 |
|
| 2010 |
Bridgham JT, Eick GN, Larroux C, Deshpande K, Harms MJ, Gauthier ME, Ortlund EA, Degnan BM, Thornton JW. Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor. Plos Biology. 8. PMID 20957188 DOI: 10.1371/Journal.Pbio.1000497 |
0.501 |
|
| 2010 |
Chen F, Gaucher EA, Leal NA, Hutter D, Havemann SA, Govindarajan S, Ortlund EA, Benner SA. Reconstructed evolutionary adaptive paths give polymerases accepting reversible terminators for sequencing and SNP detection. Proceedings of the National Academy of Sciences of the United States of America. 107: 1948-53. PMID 20080675 DOI: 10.1073/Pnas.0908463107 |
0.32 |
|
| 2009 |
Bridgham JT, Ortlund EA, Thornton JW. An epistatic ratchet constrains the direction of glucocorticoid receptor evolution. Nature. 461: 515-9. PMID 19779450 DOI: 10.1038/Nature08249 |
0.394 |
|
| 2008 |
Schaaf G, Ortlund EA, Tyeryar KR, Mousley CJ, Ile KE, Garrett TA, Ren J, Woolls MJ, Raetz CR, Redinbo MR, Bankaitis VA. Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily. Molecular Cell. 29: 191-206. PMID 18243114 DOI: 10.1016/J.Molcel.2007.11.026 |
0.635 |
|
| 2007 |
Ortlund EA, Bridgham JT, Redinbo MR, Thornton JW. Crystal structure of an ancient protein: evolution by conformational epistasis. Science (New York, N.Y.). 317: 1544-8. PMID 17702911 DOI: 10.1126/Science.1142819 |
0.645 |
|
| 2007 |
Chiswell B, Lovelace LL, Brannen C, Ortlund EA, Lebioda L, Sodetz JM. Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family. Biochimica Et Biophysica Acta. 1774: 637-44. PMID 17452033 DOI: 10.1016/J.Bbapap.2007.03.004 |
0.777 |
|
| 2005 |
Solomon IH, Hager JM, Safi R, McDonnell DP, Redinbo MR, Ortlund EA. Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity. Journal of Molecular Biology. 354: 1091-102. PMID 16289203 DOI: 10.1016/J.Jmb.2005.10.009 |
0.653 |
|
| 2005 |
Ortlund EA, Lee Y, Solomon IH, Hager JM, Safi R, Choi Y, Guan Z, Tripathy A, Raetz CR, McDonnell DP, Moore DD, Redinbo MR. Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP. Nature Structural & Molecular Biology. 12: 357-63. PMID 15723037 DOI: 10.1038/Nsmb910 |
0.69 |
|
| 2003 |
Chruszcz M, Laidler P, Monkiewicz M, Ortlund E, Lebioda L, Lewinski K. Crystal structure of a covalent intermediate of endogenous human arylsulfatase A. Journal of Inorganic Biochemistry. 96: 386-92. PMID 12888274 DOI: 10.1016/S0162-0134(03)00176-4 |
0.587 |
|
| 2003 |
Ortlund E, LaCount MW, Lebioda L. Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design. Biochemistry. 42: 383-9. PMID 12525165 DOI: 10.1021/Bi0265067 |
0.619 |
|
| 2002 |
Ortlund E, Parker CL, Schreck SF, Ginell S, Minor W, Sodetz JM, Lebioda L. Crystal structure of human complement protein C8γ at 1.2 Å resolution reveals a lipocalin fold and a distinct ligand binding site Biochemistry. 41: 7030-7037. PMID 12033936 DOI: 10.1021/Bi025696I |
0.679 |
|
| 2000 |
Ortlund E, Lacount MW, Lewinski K, Lebioda L. Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu. Biochemistry. 39: 1199-204. PMID 10684596 DOI: 10.1021/Bi991797D |
0.566 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2013 |
Gromiha MM, Pathak MC, Saraboji K, Ortlund EA, Gaucher EA. Hydrophobic environment is a key factor for the stability of thermophilic proteins Proteins: Structure, Function and Bioinformatics. 81: 715-721. PMID 23319168 DOI: 10.1002/Prot.24232 |
0.299 |
|
| 2014 |
Qiang G, Xue S, Yang JJ, Du G, Pang X, Li X, Goswami D, Griffin PR, Ortlund EA, Chan CB, Ye K. Identification of a small molecular insulin receptor agonist with potent antidiabetes activity. Diabetes. 63: 1394-409. PMID 24651808 DOI: 10.2337/Db13-0334 |
0.298 |
|
| 2020 |
Steensels S, Qiao J, Zhang Y, Maner-Smith KM, Kika N, Holman CD, Corey KE, Bracken WC, Ortlund EA, Ersoy BA. Acot9 traffics mitochondrial short-chain fatty acids towards de novo lipogenesis and glucose production in the liver. Hepatology (Baltimore, Md.). PMID 32498134 DOI: 10.1002/Hep.31409 |
0.298 |
|
| 2020 |
Wolfarth AA, Liu X, Darby TM, Boyer DJ, Spizman JB, Owens JA, Chandrasekharan B, Naudin CR, Hanley KZ, Robinson BS, Ortlund EA, Jones RM, Neish AS. Proline rich acidic protein-1 (PRAP1) protects the gastrointestinal epithelium from irradiation-induced apoptosis. Cellular and Molecular Gastroenterology and Hepatology. PMID 32629119 DOI: 10.1016/J.Jcmgh.2020.06.011 |
0.295 |
|
| 2014 |
Horton BM, Hudson WH, Ortlund EA, Shirk S, Thomas JW, Young ER, Zinzow-Kramer WM, Maney DL. Estrogen receptor α polymorphism in a species with alternative behavioral phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 111: 1443-8. PMID 24474771 DOI: 10.1073/Pnas.1317165111 |
0.278 |
|
| 2018 |
Alves-Bezerra M, Li Y, Acuña M, Ivanova AA, Corey KE, Ortlund EA, Cohen DE. Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids into Triglyceride Biosynthesis. Hepatology (Baltimore, Md.). PMID 30516845 DOI: 10.1002/Hep.30411 |
0.277 |
|
| 2020 |
Merritt JR, Grogan KE, Zinzow-Kramer WM, Sun D, Ortlund EA, Yi SV, Maney DL. A supergene-linked estrogen receptor drives alternative phenotypes in a polymorphic songbird. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817554 DOI: 10.1073/Pnas.2011347117 |
0.277 |
|
| 2020 |
Li Y, Imai N, Goyal S, Nicholls HT, Krisko T, Baqai M, Ang L, Tillman M, Ortlund EA, Cohen DE, Hagen SJ. Thioesterase Superfamily Member 1 Undergoes Stimulus‐coupled Reorganization to Regulate Metabolic Activity in Brown Adipose Tissue The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04503 |
0.276 |
|
| 2021 |
Liu X, Weikum ER, Tilo D, Vinson C, Ortlund EA. Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element. Nucleic Acids Research. PMID 34289059 DOI: 10.1093/nar/gkab605 |
0.271 |
|
| 2023 |
Druzak SA, Tardelli M, Mays SG, El Bejjani M, Mo X, Maner-Smith KM, Bowen T, Cato ML, Tillman MC, Sugiyama A, Xie Y, Fu H, Cohen DE, Ortlund EA. Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice. Nature Communications. 14: 2748. PMID 37173315 DOI: 10.1038/s41467-023-38010-w |
0.26 |
|
| 2015 |
Yu K, Whitlock JM, Lee K, Ortlund EA, Cui YY, Hartzell HC. Author response: Identification of a lipid scrambling domain in ANO6/TMEM16F Elife. DOI: 10.7554/Elife.06901.020 |
0.259 |
|
| 2023 |
Patel A, Kumar S, Lai L, Chakravarthy C, Valanparambil R, Reddy ES, Gottimukkala K, Bajpai P, Raju DR, Edara VV, Davis-Gardner ME, Linderman S, Dixit K, Sharma P, Mantus G, ... ... Ortlund EA, et al. Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response. Structure (London, England : 1993). PMID 37167972 DOI: 10.1016/j.str.2023.04.010 |
0.256 |
|
| 2019 |
Cordy RJ, Patrapuvich R, Lili LN, Cabrera-Mora M, Chien JT, Tharp GK, Khadka M, Meyer EV, Lapp SA, Joyner CJ, Garcia A, Banton S, Tran V, Luvira V, Rungin S, ... ... Ortlund EA, et al. Distinct amino acid and lipid perturbations characterize acute versus chronic malaria. Jci Insight. 4. PMID 31045574 DOI: 10.1172/Jci.Insight.125156 |
0.251 |
|
| 2017 |
Tillman M, Wang M, Ortlund E. Elucidating the mechanism of LBP-8 shuttling of lysosomal lipids into the nucleus in C. elegans Acta Crystallographica Section a Foundations and Advances. 73: a106-a106. DOI: 10.1107/S0108767317098944 |
0.247 |
|
| 2020 |
Maner-Smith KM, Goll JB, Khadka M, Jensen TL, Colucci JK, Gelber CE, Albert CJ, Bosinger SE, Franke JD, Natrajan M, Rouphael N, Johnson RA, Sanz P, Anderson EJ, Hoft DF, ... ... Ortlund EA, et al. Alterations in the Human Plasma Lipidome in Response to Tularemia Vaccination. Vaccines. 8. PMID 32722213 DOI: 10.3390/Vaccines8030414 |
0.247 |
|
| 2018 |
Deng W, Voos KM, Colucci JK, Legan ER, Ortlund EA, Lollar P, Li R. Delimiting the autoinhibitory module of von Willebrand factor. Journal of Thrombosis and Haemostasis : Jth. PMID 30053340 DOI: 10.1111/Jth.14251 |
0.241 |
|
| 2018 |
Mandal P, Feng Y, Lyons JD, Berger SB, Otani S, DeLaney A, Tharp GK, Maner-Smith K, Burd EM, Schaeffer M, Hoffman S, Capriotti C, Roback L, Young CB, Liang Z, ... Ortlund EA, et al. Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock. Immunity. 49: 42-55.e6. PMID 30021146 DOI: 10.1016/J.Immuni.2018.06.011 |
0.234 |
|
| 2022 |
Patel A, Kumar S, Lai L, Chakravarthy C, Valanparambil R, Reddy ES, Gottimukkala K, Bajpai P, Raju DR, Edara VV, Davis-Gardner ME, Linderman S, Dixit K, Sharma P, Mantus G, ... ... Ortlund EA, et al. Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response. Biorxiv : the Preprint Server For Biology. PMID 36324804 DOI: 10.1101/2022.10.24.513517 |
0.233 |
|
| 2020 |
Knudsen NH, Stanya KJ, Hyde AL, Chalom MM, Alexander RK, Liou YH, Starost KA, Gangl MR, Jacobi D, Liu S, Sopariwala DH, Fonseca-Pereira D, Li J, Hu FB, Garrett WS, ... ... Ortlund EA, et al. Interleukin-13 drives metabolic conditioning of muscle to endurance exercise. Science (New York, N.Y.). 368. PMID 32355002 DOI: 10.1126/Science.Aat3987 |
0.233 |
|
| 2022 |
Kumar S, Patel A, Lai L, Chakravarthy C, Valanparambil R, Reddy ES, Gottimukkala K, Davis-Gardner ME, Edara VV, Linderman S, Nayak K, Dixit K, Sharma P, Bajpai P, Singh V, ... ... Ortlund E, et al. Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody. Science Advances. 8: eadd2032. PMID 36197988 DOI: 10.1126/sciadv.add2032 |
0.233 |
|
| 2017 |
Francis JW, Goswami D, Novick SJ, Pascal BD, Weikum ER, Ortlund EA, Griffin PR, Kahn RA. Nucleotide binding to ARL2 in the TBCD∙ARL2∙β-tubulin complex drives conformational changes in β-tubulin. Journal of Molecular Biology. PMID 28970104 DOI: 10.1016/J.Jmb.2017.09.016 |
0.231 |
|
| 2017 |
Francis JW, Goswami D, Novick SJ, Pascal BD, Weikum ER, Ortlund EA, Griffin PR, Kahn RA. Nucleotide binding to ARL2 in the TBCD∙ARL2∙β-tubulin complex drives conformational changes in β-tubulin. Journal of Molecular Biology. PMID 28970104 DOI: 10.1016/J.Jmb.2017.09.016 |
0.231 |
|
| 2020 |
Naudin CR, Maner-Smith K, Owens JA, Wynn GM, Robinson BS, Matthews JD, Reedy AR, Luo L, Wolfarth AA, Darby TM, Ortlund EA, Jones RM. Lactococcus Lactis subsp. cremoris Elicits Protection Against Metabolic Changes Induced by a Western-style Diet. Gastroenterology. PMID 32169430 DOI: 10.1053/J.Gastro.2020.03.010 |
0.218 |
|
| 2023 |
He H, Sugiyama A, Snyder NW, Teneche MG, Liu X, Maner-Smith KM, Goessling W, Hagen SJ, Ortlund EA, Najafi-Shoushtari SH, Acuña M, Cohen DE. Acyl-CoA thioesterase 12 suppresses YAP-mediated hepatocarcinogenesis by limiting glycerolipid biosynthesis. Cancer Letters. 216210. PMID 37150501 DOI: 10.1016/j.canlet.2023.216210 |
0.213 |
|
| 2018 |
Collins JM, Walker DI, Jones DP, Tukvadze N, Liu KH, Tran VT, Uppal K, Frediani JK, Easley KA, Shenvi N, Khadka M, Ortlund EA, Kempker RR, Blumberg HM, Ziegler TR. High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans. Plos One. 13: e0205398. PMID 30308073 DOI: 10.1371/Journal.Pone.0205398 |
0.207 |
|
| 2022 |
Savini M, Folick A, Lee YT, Jin F, Cuevas A, Tillman MC, Duffy JD, Zhao Q, Neve IA, Hu PW, Yu Y, Zhang Q, Ye Y, Mair WB, Wang J, ... ... Ortlund EA, et al. Lysosome lipid signalling from the periphery to neurons regulates longevity. Nature Cell Biology. PMID 35681008 DOI: 10.1038/s41556-022-00926-8 |
0.204 |
|
| 2022 |
Kapoor-Vazirani P, Rath SK, Liu X, Shu Z, Bowen NE, Chen Y, Haji-Seyed-Javadi R, Daddacha W, Minten EV, Danelia D, Farchi D, Duong DM, Seyfried NT, Deng X, Ortlund EA, et al. SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks. Nature Communications. 13: 6707. PMID 36344525 DOI: 10.1038/s41467-022-34578-x |
0.202 |
|
| 2020 |
Krumm CS, Adura C, Liu X, Li Y, Bracken WC, Ginn JD, Glickman JF, Ortlund EA, Cohen DE. Fragment‐Based Screening to Identify Thioesterase Superfamily Member 2 (Them2) Inhibitors for the Management of Obesity‐Related Disorders The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03685 |
0.201 |
|
| 2023 |
Patel A, Kumar S, Lai L, Keen M, Valanparambil R, Chakravarthy C, Laughlin Z, Frank F, Cheedarla N, Verkerke HP, Neish AS, Roback JD, Davis CW, Wrammert J, Sharma A, ... ... Ortlund E, et al. Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron. Cell Reports. 42: 113150. PMID 37708028 DOI: 10.1016/j.celrep.2023.113150 |
0.193 |
|
| 2023 |
Krumm CS, Landzberg RS, Ramos-Espiritu L, Adura C, Liu X, Acuna M, Xie Y, Xu X, Tillman MC, Li Y, Glickman JF, Ortlund EA, Ginn JD, Cohen DE. High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease. Molecular Metabolism. 78: 101832. PMID 38403978 DOI: 10.1016/j.molmet.2023.101832 |
0.188 |
|
| 2021 |
Li Y, Imai N, Nicholls HT, Roberts BR, Goyal S, Krisko TI, Ang LH, Tillman MC, Roberts AM, Baqai M, Ortlund EA, Cohen DE, Hagen SJ. Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice. Nature Communications. 12: 3493. PMID 34108467 DOI: 10.1038/s41467-021-23595-x |
0.181 |
|
| 2020 |
Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of Biological Chemistry. PMID 33154163 DOI: 10.1074/jbc.RA120.016009 |
0.18 |
|
| 2020 |
Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of Biological Chemistry. 296: 100024. PMID 33410399 DOI: 10.1074/jbc.RA120.016009 |
0.179 |
|
| 2020 |
Suthar MS, Zimmerman MG, Kauffman RC, Mantus G, Linderman SL, Hudson WH, Vanderheiden A, Nyhoff L, Davis CW, Adekunle O, Affer M, Sherman M, Reynolds S, Verkerke HP, Alter DN, ... ... Ortlund E, et al. Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients. Cell Reports. Medicine. 1: 100040. PMID 32835303 DOI: 10.1016/j.xcrm.2020.100040 |
0.144 |
|
| 2024 |
Huneault HE, Chen CY, Cohen CC, Liu X, Jarrell ZR, He Z, DeSantos KE, Welsh JA, Maner-Smith KM, Ortlund EA, Schwimmer JB, Vos MB. Lipidome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys with Metabolic Dysfunction-Associated Steatotic Liver Disease. Metabolites. 14. PMID 38668319 DOI: 10.3390/metabo14040191 |
0.141 |
|
| 2023 |
Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, et al. APOE expression and secretion are modulated by mitochondrial dysfunction. Elife. 12. PMID 37171075 DOI: 10.7554/eLife.85779 |
0.14 |
|
| 2020 |
Suthar MS, Zimmerman M, Kauffman R, Mantus G, Linderman S, Vanderheiden A, Nyhoff L, Davis C, Adekunle S, Affer M, Sherman M, Reynolds S, Verkerke H, Alter DN, Guarner J, ... ... Ortlund E, et al. Rapid generation of neutralizing antibody responses in COVID-19 patients. Medrxiv : the Preprint Server For Health Sciences. PMID 32511565 DOI: 10.1101/2020.05.03.20084442 |
0.136 |
|
| 2023 |
Head PE, Kapoor-Vazirani P, Ganji NP, Zhang H, Rath SK, Luong NC, Haji-Seyed-Javadi R, Sesay F, Wang SY, Duong DM, Daddacha W, Minten EV, Song B, Danelia D, Liu X, ... ... Ortlund EA, et al. DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining. Nucleic Acids Research. PMID 37395399 DOI: 10.1093/nar/gkad549 |
0.134 |
|
| 2022 |
Heintz MM, Eccles JA, Olack EM, Maner-Smith KM, Ortlund EA, Baldwin WS. Human CYP2B6 produces oxylipins from polyunsaturated fatty acids and reduces diet-induced obesity. Plos One. 17: e0277053. PMID 36520866 DOI: 10.1371/journal.pone.0277053 |
0.129 |
|
| 2024 |
Ortlund E, Chen CY, Maner-Smith K, Khadka M, Ahn J, Gulbin X, Ivanova A, Dammer E, Seyfried N, Bennett D, Hajjar I. Integrative brain omics approach reveals key role for sn-1 lysophosphatidylethanolamine in Alzheimer's dementia. Research Square. PMID 38464293 DOI: 10.21203/rs.3.rs-3973736/v1 |
0.12 |
|
| 2022 |
Blanchard JW, Akay LA, Davila-Velderrain J, von Maydell D, Mathys H, Davidson SM, Effenberger A, Chen CY, Maner-Smith K, Hajjar I, Ortlund EA, Bula M, Agbas E, Ng A, Jiang X, et al. APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes. Nature. PMID 36385529 DOI: 10.1038/s41586-022-05439-w |
0.115 |
|
| 2021 |
Imai N, Nicholls HT, Alves-Bezerra M, Li Y, Ivanova AA, Ortlund EA, Cohen DE. Upregulation of Thioesterase Superfamily Member 2 in Skeletal Muscle Promotes Hepatic Steatosis and Insulin Resistance. Hepatology (Baltimore, Md.). PMID 34433228 DOI: 10.1002/hep.32122 |
0.108 |
|
| 2021 |
Collins JM, Jones DP, Sharma A, Khadka M, Liu KH, Kempker RR, Prideaux B, Maner-Smith K, Tukvadze N, Shah NS, Brust JCM, Sékaly RP, Gandhi NR, Blumberg HM, Ortlund EA, et al. TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis. Plos Pathogens. 17: e1009941. PMID 34559866 DOI: 10.1371/journal.ppat.1009941 |
0.108 |
|
| 2021 |
Liu KH, Owens JA, Saeedi B, Cohen CE, Bellissimo MP, Naudin C, Darby T, Druzak S, Maner-Smith K, Orr M, Hu X, Fernandes J, Camacho MC, Hunter-Chang S, VanInsberghe D, ... ... Ortlund E, et al. Microbial metabolite delta-valerobetaine is a diet-dependent obesogen. Nature Metabolism. 3: 1694-1705. PMID 34931082 DOI: 10.1038/s42255-021-00502-8 |
0.103 |
|
| 2022 |
Cheedarla N, Verkerke H, Potlapalli S, McLendon K, Patel A, Frank F, Damhorst G, Wu H, O'Sick W, Graciaa D, Hudaib F, Alter D, Bryksin J, Ortlund E, Guarner J, et al. Rapid, High Throughput, Automated Detection Of SARS-Cov-2 Neutralizing Antibodies Against Native-Like Vaccine And Delta Variant Spike Trimers. Research Square. PMID 35194599 DOI: 10.21203/rs.3.rs-1322411/v1 |
0.101 |
|
| 2022 |
Cheedarla N, Verkerke HP, Potlapalli S, McLendon KB, Patel A, Frank F, Damhorst GL, Wu H, Oâ Sick WH, Graciaa D, Hudaib F, Alter DN, Bryksin J, Ortlund EA, Guarner J, et al. Rapid, high throughput, automated detection of SARS-CoV-2 neutralizing antibodies against native-like vaccine and delta variant spike trimers. Medrxiv : the Preprint Server For Health Sciences. PMID 35132426 DOI: 10.1101/2022.02.01.22270279 |
0.101 |
|
| 2023 |
Cheedarla N, Verkerke HP, Potlapalli S, McLendon KB, Patel A, Frank F, O'Sick WH, Cheedarla S, Baugh TJ, Damhorst GL, Wu H, Graciaa D, Hudaib F, Alter DN, Bryksin J, ... Ortlund EA, et al. Rapid, high throughput, automated detection of SARS-CoV-2 neutralizing antibodies against Wuhan-WT, delta and omicron BA1, BA2 spike trimers. Iscience. 26: 108256. PMID 37965140 DOI: 10.1016/j.isci.2023.108256 |
0.101 |
|
| 2022 |
Heintz MM, Kumar R, Maner-Smith KM, Ortlund EA, Baldwin WS. Age- and Diet-Dependent Changes in Hepatic Lipidomic Profiles of Phospholipids in Male Mice: Age Acceleration in Cyp2b-Null Mice. Journal of Lipids. 2022: 7122738. PMID 35391786 DOI: 10.1155/2022/7122738 |
0.094 |
|
| 2019 |
Khadka M, Todor A, Maner-Smith KM, Colucci JK, Tran V, Gaul DA, Anderson EJ, Natrajan MS, Rouphael N, Mulligan MJ, McDonald CE, Suthar M, Li S, Ortlund EA. The Effect of Anticoagulants, Temperature, and Time on the Human Plasma Metabolome and Lipidome from Healthy Donors as Determined by Liquid Chromatography-Mass Spectrometry. Biomolecules. 9. PMID 31126114 DOI: 10.3390/biom9050200 |
0.091 |
|
| 2024 |
Many GM, Sanford JA, Sagendorf TJ, Hou Z, Nigro P, Whytock KL, Amar D, Caputo T, Gay NR, Gaul DA, Hirshman MF, Jimenez-Morales D, Lindholm ME, Muehlbauer MJ, Vamvini M, ... ... Ortlund EA, et al. Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue. Nature Metabolism. PMID 38693320 DOI: 10.1038/s42255-023-00959-9 |
0.085 |
|
| 2022 |
Frank F, Keen MM, Rao A, Bassit L, Liu X, Bowers HB, Patel AB, Cato ML, Sullivan JA, Greenleaf M, Piantadosi A, Lam WA, Hudson WH, Ortlund EA. Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests. Cell. 185: 3603-3616.e13. PMID 36084631 DOI: 10.1016/j.cell.2022.08.010 |
0.076 |
|
| 2023 |
Many GM, Sanford JA, Sagendorf TJ, Hou Z, Nigro P, Whytock K, Amar D, Caputo T, Gay NR, Gaul DA, Hirshman M, Jimenez-Morales D, Lindholm ME, Muehlbauer MJ, Vamvini M, ... ... Ortlund EA, et al. Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue. Biorxiv : the Preprint Server For Biology. PMID 36778330 DOI: 10.1101/2023.02.03.527012 |
0.072 |
|
| 2023 |
Druzak S, Iffrig E, Roberts BR, Zhang T, Fibben KS, Sakurai Y, Verkerke HP, Rostad CA, Chahroudi A, Schneider F, Wong AKH, Roberts AM, Chandler JD, Kim SO, Mosunjac M, ... ... Ortlund EA, et al. Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19. Nature Communications. 14: 1638. PMID 37015925 DOI: 10.1038/s41467-023-37269-3 |
0.072 |
|
| 2021 |
Creager R, Blackwood J, Pribyl T, Bassit L, Rao A, Greenleaf M, Frank F, Lam W, Ortlund E, Schinazi R, Greninger A, Cirrincione M, Gort D, Kennedy E, Samuta A, et al. RADx Variant Task Force Program for Assessing the Impact of Variants on SARS-CoV-2 Molecular and Antigen Tests. Ieee Open Journal of Engineering in Medicine and Biology. 2: 286-290. PMID 35257097 DOI: 10.1109/OJEMB.2021.3116490 |
0.065 |
|
| 2022 |
Farmer S, Razin V, Peagler AF, Strickler S, Fain WB, Damhorst GL, Kempker RR, Pollock NR, Brand O, Seitter B, Heilman SS, Nehl EJ, Levy JM, Gottfried DS, Martin GS, ... ... Ortlund E, et al. Don't Forget About Human Factors: Lessons Learned from COVID-19 Point-of-Care Testing. Cell Reports Methods. 100222. PMID 35527805 DOI: 10.1016/j.crmeth.2022.100222 |
0.055 |
|
| 2023 |
Rao A, Westbrook A, Bassit L, Parsons R, Fitts E, Greenleaf M, McLendon K, Sullivan JA, Oâ Sick W, Baugh T, Bowers HB, Frank F, Wang E, Le M, Frediani J, ... ... Ortlund EA, et al. Sensitivity of Rapid Antigen Tests Against SARS-CoV-2 Omicron and Delta Variants. Medrxiv : the Preprint Server For Health Sciences. PMID 36798414 DOI: 10.1101/2023.02.09.23285583 |
0.053 |
|
| 2023 |
Rao A, Westbrook A, Bassit L, Parsons R, Fitts E, Greenleaf M, McLendon K, Sullivan JA, O'Sick W, Baugh T, Bowers HB, Frank F, Wang E, Le M, Frediani J, ... ... Ortlund EA, et al. Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants. Journal of Clinical Microbiology. e0013823. PMID 37728336 DOI: 10.1128/jcm.00138-23 |
0.052 |
|
| 2023 |
Huber E, Groll M, Ortlund E. Meet the authors: Dr. Eva Huber, Dr. Michael Groll, and Dr. Eric Ortlund. Structure (London, England : 1993). 31: 762-763. PMID 37419100 DOI: 10.1016/j.str.2023.06.003 |
0.052 |
|
| 2022 |
Maner-Smith KM, Ferranti E, Dunlop A, Corwin E, Ortlund EA. African American Women with Cardiometabolic Complications of Pregnancy Have Decreased Serum Abundance of Specialized Pro-Resolving Lipid Mediators and Endocannabinoids. Nutrients. 15. PMID 36615797 DOI: 10.3390/nu15010140 |
0.051 |
|
| 2012 |
Ortlund E. Review of Origin Myths and Holy Places in the Old Testament: A Study of Aetiological Narratives (Copenhagen International Seminar; London & Oakville: Equinox, 2011). Journal of Hebrew Scriptures. 12. DOI: 10.5508/jhs.201.v12.r21 |
0.04 |
|
| 2008 |
Ortlund E. Book Review: THE OLD TESTAMENT PROPHETS AND JESUS Judith Lang, They Looked at God: The Great Prophets and Their Relation to Christ (London: New City, 2005. £9.95. pp. 208. ISBN 0—904287—95—5) The Expository Times. 119: 619-619. DOI: 10.1177/00145246081190121208 |
0.039 |
|
| 2018 |
Ortlund E. Book Review: Studies in Isaiah: Tommy Wassermann, Greger Andersson and David Willgren (eds), Studies in Isaiah: History, Theology and Reception The Expository Times. 129: 253-253. DOI: 10.1177/0014524617746830 |
0.037 |
|
| 2010 |
Ortlund E. Reversed (Chrono-)Logical Sequence in Isaiah 1-39: Some Implications for Theories of Redaction Journal For the Study of the Old Testament. 35: 209-224. DOI: 10.1177/0309089210386017 |
0.031 |
|
| 2015 |
Ortlund E. Deconstruction in Qohelet: A Response to Mark Sneed Journal For the Study of the Old Testament. 40: 239-256. DOI: 10.1177/0309089215611547 |
0.028 |
|
| 2020 |
Suthar MS, Zimmerman MG, Kauffman RC, Mantus G, Linderman SL, Hudson WH, Vanderheiden A, Nyhoff L, Davis CW, Adekunle O, Affer M, Sherman M, Reynolds S, Verkerke HP, Alter DN, ... ... Ortlund E, et al. Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients Cell Reports Medicine. 1: 100040. DOI: 10.1016/j.xcrm.2020.100040 |
0.025 |
|
| 2006 |
Ortlund E. Lack of Focus Hampers Discussion The Expository Times. 117: 281-281. DOI: 10.1177/001452460611700705 |
0.021 |
|
| 2008 |
Ortlund E. Book Review: A TEPID APOLOGY FOR GENESIS 1—3 William H. Jennings, Storms Over Genesis: Biblical Battleground in America's Wars of Religion (Minneapolis, MN: Fortress Press, 2007. $17.00. pp. 149. ISBN 978—0—8006—6211—0) The Expository Times. 120: 47-48. DOI: 10.1177/00145246081200011207 |
0.019 |
|
| 2005 |
Ortlund E. Book Review: The Theological Significance of Church Music The Expository Times. 117: 121-122. DOI: 10.1177/001452460511700315 |
0.016 |
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| 2006 |
Ortlund E. Book Review: David’s Unloved Wife: A Critique of Royal Ideology? The Expository Times. 117: 477-478. DOI: 10.1177/0014524606067970 |
0.013 |
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| 2006 |
Ortlund E. The Waters in The Old Testament The Expository Times. 117: 451-451. DOI: 10.1177/0014524606067979 |
0.011 |
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| 2008 |
Ortlund E. Book Review: What Does It Mean To Be a People? The Expository Times. 119: 353-353. DOI: 10.1177/00145246081190071107 |
0.01 |
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| 2006 |
Ortlund E. Order Out of Chaos The Expository Times. 117: 191-191. DOI: 10.1177/001452460611700507 |
0.01 |
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| Hide low-probability matches. |