Dylan J. Taatjes - Publications

Chemistry University of Colorado, Boulder, Boulder, CO, United States 

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rimel JK, Poss ZC, Erickson B, Maas ZL, Ebmeier CC, Johnson JL, Decker TM, Yaron TM, Bradley MJ, Hamman KB, Hu S, Malojcic G, Marineau JJ, White PW, Brault M, ... ... Taatjes DJ, et al. Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription. Genes & Development. PMID 33060135 DOI: 10.1101/gad.341545.120  0.68
2019 Steinparzer I, Sedlyarov V, Rubin JD, Eislmayr K, Galbraith MD, Levandowski CB, Vcelkova T, Sneezum L, Wascher F, Amman F, Kleinova R, Bender H, Andrysik Z, Espinosa JM, Superti-Furga G, ... ... Taatjes DJ, et al. Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Molecular Cell. PMID 31495563 DOI: 10.1016/J.Molcel.2019.07.034  0.52
2019 Guard SE, Poss ZC, Ebmeier CC, Pagratis M, Simpson H, Taatjes DJ, Old WM. The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair. Scientific Reports. 9: 6539. PMID 31024071 DOI: 10.1038/S41598-019-42990-5  0.68
2017 Ebmeier CC, Erickson B, Allen BL, Allen MA, Kim H, Fong N, Jacobsen JR, Liang K, Shilatifard A, Dowell RD, Old WM, Bentley DL, Taatjes DJ. Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications. Cell Reports. 20: 1173-1186. PMID 28768201 DOI: 10.1016/J.Celrep.2017.07.021  0.68
2017 Audetat KA, Galbraith MD, Odell AT, Lee T, Pandey A, Espinosa JM, Dowell RD, Taatjes DJ. A kinase-independent role for CDK19 in p53 response. Molecular and Cellular Biology. PMID 28416637 DOI: 10.1128/Mcb.00626-16  0.52
2016 Passmore LA, Taatjes DJ. Macromolecular Complexes in Transcription and Co-transcriptional RNA Processing. Journal of Molecular Biology. PMID 27155574 DOI: 10.1016/J.Jmb.2016.05.001  1
2016 Poss ZC, Ebmeier CC, Odell AT, Tangpeerachaikul A, Lee T, Pelish HE, Shair MD, Dowell RD, Old WM, Taatjes DJ. Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics. Cell Reports. PMID 27050516 DOI: 10.1016/J.Celrep.2016.03.030  1
2015 Rubin JD, Taatjes DJ. Molecular biology: Mediating transcription and RNA export. Nature. 526: 199-200. PMID 26450052 DOI: 10.1038/526199A  1
2015 Pelish HE, Liau BB, Nitulescu II, Tangpeerachaikul A, Poss ZC, Da Silva DH, Caruso BT, Arefolov A, Fadeyi O, Christie AL, Du K, Banka D, Schneider EV, Jestel A, Zou G, ... ... Taatjes DJ, et al. Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature. 526: 273-6. PMID 26416749 DOI: 10.1038/Nature14904  1
2015 Luo J, Cimermancic P, Viswanath S, Ebmeier CC, Kim B, Dehecq M, Raman V, Greenberg CH, Pellarin R, Sali A, Taatjes DJ, Hahn S, Ranish J. Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH. Molecular Cell. 59: 794-806. PMID 26340423 DOI: 10.1016/J.Molcel.2015.07.016  1
2015 Fant CB, Taatjes DJ. All in the family: a portrait of a nuclear receptor co-activator complex. Molecular Cell. 57: 952-4. PMID 25794613 DOI: 10.1016/J.Molcel.2015.03.001  1
2015 Allen BL, Taatjes DJ. The Mediator complex: a central integrator of transcription. Nature Reviews. Molecular Cell Biology. 16: 155-66. PMID 25693131 DOI: 10.1038/Nrm3951  1
2014 Bunch H, Zheng X, Burkholder A, Dillon ST, Motola S, Birrane G, Ebmeier CC, Levine S, Fargo D, Hu G, Taatjes DJ, Calderwood SK. TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release. Nature Structural & Molecular Biology. 21: 876-83. PMID 25173174 DOI: 10.1038/Nsmb.2878  1
2014 Sennett NC, Taatjes DJ. Mediator redefines itself. Cell Research. 24: 775-6. PMID 24913192 DOI: 10.1038/Cr.2014.76  1
2013 Phillips AJ, Taatjes DJ. Small molecule probes to target the human Mediator complex. Israel Journal of Chemistry. 53: 588-595. PMID 25705053 DOI: 10.1002/Ijch.201300039  1
2013 Lin SC, Taatjes DJ. ΔNp53 and aging. Aging. 5: 717-8. PMID 24145197  1
2013 Poss ZC, Ebmeier CC, Taatjes DJ. The Mediator complex and transcription regulation. Critical Reviews in Biochemistry and Molecular Biology. 48: 575-608. PMID 24088064 DOI: 10.3109/10409238.2013.840259  1
2013 Lin SC, Karoly ED, Taatjes DJ. The human ΔNp53 isoform triggers metabolic and gene expression changes that activate mTOR and alter mitochondrial function. Aging Cell. 12: 863-72. PMID 23734707 DOI: 10.1111/Acel.12108  1
2013 He Y, Fang J, Taatjes DJ, Nogales E. Structural visualization of key steps in human transcription initiation. Nature. 495: 481-6. PMID 23446344 DOI: 10.1038/Nature11991  1
2013 Lai F, Orom UA, Cesaroni M, Beringer M, Taatjes DJ, Blobel GA, Shiekhattar R. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature. 494: 497-501. PMID 23417068 DOI: 10.1038/Nature11884  1
2013 Bancerek J, Poss ZC, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dölken L, Strobl B, Müller M, Taatjes DJ, Kovarik P. CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response. Immunity. 38: 250-62. PMID 23352233 DOI: 10.1016/J.Immuni.2012.10.017  0.68
2013 Davis MA, Larimore EA, Fissel BM, Swanger J, Taatjes DJ, Clurman BE. The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator. Genes & Development. 27: 151-6. PMID 23322298 DOI: 10.1101/Gad.207720.112  1
2012 Schwartz JC, Ebmeier CC, Podell ER, Heimiller J, Taatjes DJ, Cech TR. FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. Genes & Development. 26: 2690-5. PMID 23249733 DOI: 10.1101/Gad.204602.112  1
2012 Bernecky C, Taatjes DJ. Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly. Journal of Molecular Biology. 417: 387-94. PMID 22343046 DOI: 10.1016/J.Jmb.2012.02.014  1
2011 Taylor DJ, Podell ER, Taatjes DJ, Cech TR. Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA. Journal of Molecular Biology. 410: 10-7. PMID 21596049 DOI: 10.1016/J.Jmb.2011.04.049  1
2011 Bernecky C, Grob P, Ebmeier CC, Nogales E, Taatjes DJ. Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly. Plos Biology. 9: e1000603. PMID 21468301 DOI: 10.1371/Journal.Pbio.1000603  1
2011 Knuesel MT, Taatjes DJ. Mediator and post-recruitment regulation of RNA polymerase II. Transcription. 2: 28-31. PMID 21326907 DOI: 10.4161/trns.2.1.13950  1
2011 Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, Van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA. Mediator and cohesin connect gene expression and chromatin architecture (Nature (2010) 467 (430-435)) Nature. 472: 247. DOI: 10.1038/Nature09930  1
2010 De Carlo S, Lin SC, Taatjes DJ, Hoenger A. Molecular basis of transcription initiation in Archaea. Transcription. 1: 103-11. PMID 21326901 DOI: 10.4161/trns.1.2.13189  1
2010 Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA. Mediator and cohesin connect gene expression and chromatin architecture. Nature. 467: 430-5. PMID 20720539 DOI: 10.1038/nature09380  1
2010 Ebmeier CC, Taatjes DJ. Activator-Mediator binding regulates Mediator-cofactor interactions. Proceedings of the National Academy of Sciences of the United States of America. 107: 11283-8. PMID 20534441 DOI: 10.1073/Pnas.0914215107  1
2010 Meyer KD, Lin SC, Bernecky C, Gao Y, Taatjes DJ. p53 activates transcription by directing structural shifts in Mediator. Nature Structural & Molecular Biology. 17: 753-60. PMID 20453859 DOI: 10.1038/Nsmb.1816  1
2010 Taatjes DJ. The human Mediator complex: a versatile, genome-wide regulator of transcription. Trends in Biochemical Sciences. 35: 315-22. PMID 20299225 DOI: 10.1016/J.Tibs.2010.02.004  1
2010 Donner AJ, Ebmeier CC, Taatjes DJ, Espinosa JM. CDK8 is a positive regulator of transcriptional elongation within the serum response network. Nature Structural & Molecular Biology. 17: 194-201. PMID 20098423 DOI: 10.1038/Nsmb.1752  1
2009 Knuesel MT, Meyer KD, Bernecky C, Taatjes DJ. The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function. Genes & Development. 23: 439-51. PMID 19240132 DOI: 10.1101/Gad.1767009  1
2009 Knuesel MT, Meyer KD, Donner AJ, Espinosa JM, Taatjes DJ. The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator. Molecular and Cellular Biology. 29: 650-61. PMID 19047373 DOI: 10.1128/Mcb.00993-08  1
2008 Panning B, Taatjes DJ. Transcriptional regulation: it takes a village. Molecular Cell. 31: 622-9. PMID 18775322 DOI: 10.1016/J.Molcel.2008.08.013  1
2008 Meyer KD, Donner AJ, Knuesel MT, York AG, Espinosa JM, Taatjes DJ. Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3. The Embo Journal. 27: 1447-57. PMID 18418385 DOI: 10.1038/Emboj.2008.78  1
2004 Taatjes DJ, Schneider-Poetsch T, Tjian R. Distinct conformational states of nuclear receptor-bound CRSP-Med complexes. Nature Structural & Molecular Biology. 11: 664-71. PMID 15195149 DOI: 10.1038/Nsmb789  1
2004 Taatjes DJ, Tjian R. Structure and function of CRSP/Med2; a promoter-selective transcriptional coactivator complex. Molecular Cell. 14: 675-83. PMID 15175162 DOI: 10.1016/J.Molcel.2004.05.014  1
2004 Taatjes DJ, Marr MT, Tjian R. Regulatory diversity among metazoan co-activator complexes. Nature Reviews. Molecular Cell Biology. 5: 403-10. PMID 15122353 DOI: 10.1038/Nrm1369  1
2002 Dernell WS, Powers BE, Taatjes DJ, Cogan P, Gaudiano G, Koch TH. Evaluation of the epidoxorubicin--formaldehyde conjugate, epidoxoform, in a mouse mammary carcinoma model. Cancer Investigation. 20: 713-24. PMID 12197227 DOI: 10.1081/Cnv-120003540  1
2002 Näär AM, Taatjes DJ, Zhai W, Nogales E, Tjian R. Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes & Development. 16: 1339-44. PMID 12050112 DOI: 10.1101/Gad.987602  1
2002 Taatjes DJ, Näär AM, Andel F, Nogales E, Tjian R. Structure, function, and activator-induced conformations of the CRSP coactivator. Science (New York, N.Y.). 295: 1058-62. PMID 11834832 DOI: 10.1126/Science.1065249  1
2000 Kato S, Burke PJ, Fenick DJ, Taatjes DJ, Bierbaum VM, Koch TH. Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs. Chemical Research in Toxicology. 13: 509-16. PMID 10858324 DOI: 10.1021/Tx000008M  1
1999 Podell ER, Harrington DJ, Taatjes DJ, Koch TH. Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells Acta Crystallographica Section D: Biological Crystallography. 55: 1516-1523. PMID 10489446 DOI: 10.1107/S0907444999008161  1
1999 Taatjes DJ, Fenick DJ, Koch TH. Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines Chemical Research in Toxicology. 12: 588-596. PMID 10409398 DOI: 10.1021/Tx990008Q  1
1999 Taatjes DJ, Koch TH. Growth inhibition, nuclear uptake, and retention of anthracycline-formaldehyde conjugates in prostate cancer cells relative to clinical anthracyclines Anticancer Research. 19: 1201-1208. PMID 10368676  1
1998 Taatjes DJ, Fenick DJ, Gaudiano G, Koch TH. A redox pathway leading to the alkylation of nucleic acids by doxorubicin and related anthracyclines: Application to the design of antitumor drugs for resistant cancer Current Pharmaceutical Design. 4: 203-218. PMID 10197040  1
1998 Taatjes DJ, Fenick DJ, Koch TH. Epidoxoform: A hydrolytically more stable anthracycline-formaldehyde conjugate toxic to resistant tumor cells Journal of Medicinal Chemistry. 41: 1306-1314. PMID 9548820 DOI: 10.1021/Jm970739S  1
1997 Taatjes DJ, Gaudiano G, Koch TH. Production of formaldehyde and DNA-adriamycin or DNA-daunomycin adducts, initiated through redox chemistry of dithiothreitol/iron, xanthine oxidase/NADH/iron, or glutathione/iron Chemical Research in Toxicology. 10: 953-961. PMID 9305576 DOI: 10.1021/Tx970064W  1
1997 Fenick DJ, Taatjes DJ, Koch TH. Doxoform and daunoform: Anthracycline-formaldehyde conjugates toxic to resistant tumor cells Journal of Medicinal Chemistry. 40: 2452-2461. PMID 9258351 DOI: 10.1021/Jm970237E  1
1997 Taatjes DJ, Gaudiano G, Resing K, Koch TH. Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin Journal of Medicinal Chemistry. 40: 1276-1286. PMID 9111302 DOI: 10.1021/Jm960835D  1
1996 Taatjes DJ, Gaudiano G, Resing K, Koch TH. Alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin Journal of Medicinal Chemistry. 39: 4135-4138. PMID 8863788 DOI: 10.1021/Jm960519Z  1
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