| Year |
Citation |
Score |
| 2024 |
Liu ZJ, Thom C, Nitulescu II, Pelish HE, Rimsza LM, Teruel-Montoya R, Ferrer-Marin F, Shair MD, Sola-Visner M. CDK8/19 inhibition triggers a switch from mitosis to endomitosis in cord blood megakaryocytes. British Journal of Haematology. PMID 39413769 DOI: 10.1111/bjh.19836 |
0.647 |
|
| 2024 |
Lin JJ, Horan JC, Tangpeerachaikul A, Swalduz A, Valdivia A, Johnson ML, Besse B, Camidge DR, Fujino T, Yoda S, Nguyen-Phuong L, Mizuta H, Bigot L, Nobre C, Lee JB, ... ... Pelish HE, et al. NVL-655 Is a Selective and Brain-Penetrant Inhibitor of Diverse ALK-Mutant Oncoproteins, Including Lorlatinib-Resistant Compound Mutations. Cancer Discovery. OF1-OF20. PMID 39269178 DOI: 10.1158/2159-8290.CD-24-0231 |
0.622 |
|
| 2022 |
Drilon A, Horan JC, Tangpeerachaikul A, Besse B, Ou SI, Gadgeel SM, Camidge DR, van der Wekken AJ, Nguyen-Phuong L, Acker A, Keddy C, Nicholson KS, Yoda S, Mente S, Sun Y, ... ... Pelish HE, et al. NVL-520 is a selective, TRK-sparing, and brain-penetrant inhibitor of ROS1 fusions and secondary resistance mutations. Cancer Discovery. PMID 36511802 DOI: 10.1158/2159-8290.CD-22-0968 |
0.603 |
|
| 2017 |
Nitulescu II, Meyer SC, Wen QJ, Crispino JD, Lemieux ME, Levine RL, Pelish HE, Shair MD. Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation. Ebiomedicine. 26: 112-125. PMID 29239838 DOI: 10.1016/J.Ebiom.2017.11.013 |
0.676 |
|
| 2017 |
Tahara T, Streit U, Pelish HE, Shair MD. STAT3 Inhibitory Activity of Structurally Simplified Withaferin A Analogues. Organic Letters. PMID 28350459 DOI: 10.1021/Acs.Orglett.7B00332 |
0.636 |
|
| 2016 |
Poss ZC, Ebmeier CC, Odell AT, Tangpeerachaikul A, Lee T, Pelish HE, Shair MD, Dowell RD, Old WM, Taatjes DJ. Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics. Cell Reports. PMID 27050516 DOI: 10.1016/J.Celrep.2016.03.030 |
0.675 |
|
| 2015 |
Pelish HE, Liau BB, Nitulescu II, Tangpeerachaikul A, Poss ZC, Da Silva DH, Caruso BT, Arefolov A, Fadeyi O, Christie AL, Du K, Banka D, Schneider EV, Jestel A, Zou G, et al. Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature. 526: 273-6. PMID 26416749 DOI: 10.1038/Nature14904 |
0.677 |
|
| 2015 |
Liu Z, Nitulescu I, Pelish H, Shair M, Sola-Visner M. Mediator Kinase Inhibition Triggers a Phenotypic Switch from Neonatal to Adult-like Megakaryopoiesis Blood. 126: 1171-1171. DOI: 10.1182/Blood.V126.23.1171.1171 |
0.663 |
|
| 2011 |
Marks KM, Park ES, Arefolov A, Russo K, Ishihara K, Ring JE, Clardy J, Clarke AS, Pelish HE. The selectivity of austocystin D arises from cell-line-specific drug activation by cytochrome P450 enzymes. Journal of Natural Products. 74: 567-73. PMID 21348461 DOI: 10.1021/Np100429S |
0.333 |
|
| 2008 |
Kirchhausen T, Macia E, Pelish HE. Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis. Methods in Enzymology. 438: 77-93. PMID 18413242 DOI: 10.1016/S0076-6879(07)38006-3 |
0.438 |
|
| 2006 |
Xu B, Pelish H, Kirchhausen T, Hammond GB. Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading. Organic & Biomolecular Chemistry. 4: 4149-57. PMID 17312971 DOI: 10.1039/B609143A |
0.422 |
|
| 2006 |
Pelish HE, Ciesla W, Tanaka N, Reddy K, Shair MD, Kirchhausen T, Lencer WI. The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells. Biochemical Pharmacology. 71: 1720-6. PMID 16677615 DOI: 10.1016/J.Bcp.2006.03.011 |
0.641 |
|
| 2006 |
Peterson JR, Lebensohn AM, Pelish HE, Kirschner MW. Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components. Chemistry & Biology. 13: 443-52. PMID 16632257 DOI: 10.1016/J.Chembiol.2006.02.009 |
0.414 |
|
| 2006 |
Pelish HE, Peterson JR, Salvarezza SB, Rodriguez-Boulan E, Chen JL, Stamnes M, Macia E, Feng Y, Shair MD, Kirchhausen T. Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro. Nature Chemical Biology. 2: 39-46. PMID 16408091 DOI: 10.1038/Nchembio751 |
0.652 |
|
| 2001 |
Pelish HE, Westwood NJ, Feng Y, Kirchhausen T, Shair MD. Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product. Journal of the American Chemical Society. 123: 6740-1. PMID 11439080 DOI: 10.1021/Ja016093H |
0.677 |
|
| 2001 |
Tallarico JA, Depew KM, Pelish HE, Westwood NJ, Lindsley CW, Shair MD, Schreiber SL, Foley MA. An alkylsilyl-tethered, high-capacity solid support amenable to diversity-oriented synthesis for one-bead, one-stock solution chemical genetics. Journal of Combinatorial Chemistry. 3: 312-8. PMID 11350255 DOI: 10.1021/Cc000107I |
0.67 |
|
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